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2014

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Development Of A Prototype Lateral Flow Immunoassay (Lfi) For The Rapid Diagnosis Of Melioidosis., Raymond L. Houghton, Dana E. Reed, Mark A. Hubbard, Michael J. Dillon, Hongjing Chen, Bart J. Currie, Mark Mayo, Derek S. Sarovich, Vanessa Theobald, Direk Limmathurotsakul, Gumphol Wongsuvan, Narisara Chantratita, Sharon J. Peacock, Alex R. Hoffmaster, Brea Duval, Paul J. Brett, Mary N. Burtnick, David P. Aucoin Jan 2014

Development Of A Prototype Lateral Flow Immunoassay (Lfi) For The Rapid Diagnosis Of Melioidosis., Raymond L. Houghton, Dana E. Reed, Mark A. Hubbard, Michael J. Dillon, Hongjing Chen, Bart J. Currie, Mark Mayo, Derek S. Sarovich, Vanessa Theobald, Direk Limmathurotsakul, Gumphol Wongsuvan, Narisara Chantratita, Sharon J. Peacock, Alex R. Hoffmaster, Brea Duval, Paul J. Brett, Mary N. Burtnick, David P. Aucoin

Peninsula Medical School

Burkholderia pseudomallei is a soil-dwelling bacterium and the causative agent of melioidosis. Isolation of B. pseudomallei from clinical samples is the "gold standard" for the diagnosis of melioidosis; results can take 3-7 days to produce. Alternatively, antibody-based tests have low specificity due to a high percentage of seropositive individuals in endemic areas. There is a clear need to develop a rapid point-of-care antigen detection assay for the diagnosis of melioidosis. Previously, we employed In vivo Microbial Antigen Discovery (InMAD) to identify potential B. pseudomallei diagnostic biomarkers. The B. pseudomallei capsular polysaccharide (CPS) and numerous protein antigens were identified as potential …


Parameterization Of Pharmaceutical Emissions And Removal Rates For Use In Uk Predictive Exposure Models: Steroid Estrogens As A Case Study, Jd Heffley, Sdw Comber, Bw Wheeler, Ch Redshaw Jan 2014

Parameterization Of Pharmaceutical Emissions And Removal Rates For Use In Uk Predictive Exposure Models: Steroid Estrogens As A Case Study, Jd Heffley, Sdw Comber, Bw Wheeler, Ch Redshaw

School of Geography, Earth and Environmental Sciences

Using local population characteristics and prescription data to predict pharmaceutical concentrations in sewage influent and effluent.