Digital Commons Network^™

Distinguishing West Nile Virus Infection Using A Recombinant Envelope Protein With Mutations In The Conserved Fusion-Loop, Stefan Chabierski, Luisa Barzon, Anna Papa, Matthias Niedrig, Jonathan L. Bramson, Justin M. Richner, Giorgio Palu, Michael S. Diamond, Sebastian Ulbert

Open Access Publications

No abstract provided.

Genome-Wide Association Study Of Arabidopsis Thaliana Leaf Microbial Community, Matthew W. Horton, Natacha Bodenhausen, Kathleen Beilsmith, Dazhe Meng, Brian D. Muegge, Sathish Subramanian, M. Madlen Vetter, Bjarni J. Vilhjálmsson, Magnus Nordborg, Jeffrey I. Gordon, Joy Bergelson

Open Access Publications

No abstract provided.

Bhlhe40 Controls Cytokine Production By T Cells And Is Essential For Pathogenicity In Autoimmune Neuroinflammation, Chih-Chung Lin, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Julia Sim, Javier A. Carrero, Chun Chou, Lindsey E. Cook, Takeshi Egawa, Reshma Taneja, Theresa L. Murphy, John H. Russell, Brian T. Edelson

Open Access Publications

No abstract provided.

Francisella Tularensis Schu S4 Lipopolysaccharide Core Sugar And O-Antigen Mutants Are Attenuated In A Mouse Model Of Tularemia, Jed A. Rasmussen, Deborah M.B. Post, Bradford W. Gibson, Stephen R. Lindemann, Michael A. Apicella, David K. Meyerholz, Bradley D. Jones

Open Access Publications

No abstract provided.

Enterotoxigenic Escherichia Coli Secretes A Highly Conserved Mucin-Degrading Metalloprotease To Effectively Engage Intestinal Epithelial Cells, Qingwei Luo, Pardeep Kumar, Tim J. Vickers, Alaullah Sheikh, Warren G. Lewis, David A. Rasko, Jeticia Sistrunk, James M. Fleckenstein

Open Access Publications

No abstract provided.

Genome-Wide Rnai Screen Identifies Broadly-Acting Host Factors That Inhibit Arbovirus Infection, Ari Yasunaga, Sheri L. Hanna, Jianqing Li, Hyelim Cho, Patrick P. Rose, Anna Spiridigliozzi, Beth Gold, Michael S. Diamond, Sara Cherry

Open Access Publications

No abstract provided.

Absence Of Calcium‐Independent Phospholipase A2Β Impairs Platelet‐Activating Factor Production And Inflammatory Cell Recruitment In Trypanosoma Cruzi‐Infected Endothelial Cells, Janhavi Sharma, Christopher S. Eickhoff, Daniel F. Hoft, John O. Marentette, John Turk, Jane Mchowat

Open Access Publications

No abstract provided.

Pulmonary Phaeohyphomycosis Caused By Phaeoacremonium In A Kidney Transplant Recipient: Successful Treatment With Posaconazole, Saivaralaxmi Monaganti, Carlos A Q Santos, Andrea Markwardt, Morgan A. Pence, Daniel C. Brennan

Open Access Publications

No abstract provided.

Congenitally Acquired Persistent Lymphocytic Choriomeningitis Viral Infection Reduces Neuronal Progenitor Pools In The Adult Hippocampus And Subventricular Zone, Tony Sun, Michael J. Vasek, Robyn S. Klein

Open Access Publications

No abstract provided.

Metabolic Control Of Dendritic Cell Activation And Function: Recent Advances And Clinical Implications, Bart Everts, Edward J. Pearce

Open Access Publications

No abstract provided.

Integrated School-Based Surveillance For Soil-Transmitted Helminth Infections And Lymphatic Filariasis In Gampaha District, Sri Lanka, Sharmini Guanwardena, Nipul K. Guanawardena, Ganga Kahathuduwa, Nadira D. Karunaweera, Nilanthi R. De Silva, Udaya B. Ranasinghe, Sandhya D. Samarasekara, Kumara C. Nagodavithana, Ramakrishna U. Rao, Maria P. Rebollo, Gary J. Weil

Open Access Publications

No abstract provided.

Molecular Epidemiology Of Carbapenem-Nonsusceptible Acinetobacter Baumannii In The United States, Jennifer M. Adams-Haduch, Ezenwa O. Onuoha, Tatiana Bogdanovich, Guo-Bao Tian, Jonas Marschall, Carl M. Urban, Brad J. Spellberg, Diane Rhee, Diane C. Halstead, Anthony W. Pasculle, Yohei Doi

Open Access Publications

No abstract provided.

Trust In Health Care Providers: Factors Predicting Trust Among Homeless Veterans Over Time, Carrisa Van Den Berk-Clark, James Mcguire

Open Access Publications

No abstract provided.

The Triggering Receptor Expressed On Myeloid Cells 2 Inhibits Complement Component 1q Effector Mechanisms And Exerts Detrimental Effects During Pneumococcal Pneumonia, Susan Gilfillan, Marco Colonna, Et Al

Open Access Publications

No abstract provided.

Parallels Between Cancer And Infectious Disease, Richard S. Hotchkiss, Lyle L. Moldawer

Open Access Publications

No abstract provided.

Whole-Genome Analyses Of Enterococcus Faecium Isolates With Diverse Daptomycin Mics, Lorena Diaz, Truc T. Tran, Jose M. Munita, William R. Miller, Sandra Rincon, Lina P. Carvajal, Aye Wollam, Jinnethe Reyes, Diana Panesso, Natalia L. Rojas, Yousif Shamoo, Barbara E. Murray, George M. Weinstock, Cesar A. Arias

Open Access Publications

No abstract provided.

Knowledge, Attitudes And Practices Of Parents Regarding Antibiotic Use In Children, Saad Siddiqui, Mubeen Sultan Cheema, Romana Ayub, Noreen Shah, Ameer Hamza, Sheraz Hussain, Muhammad Hamza Khan, Syed Musa Raza

Department of Radiology

Background: Emerging resistance to antimicrobial chemotherapy is becoming a challenge for medicine in recent times. Un-prescribed use of antibiotics is a major contributor to development of this problem. In Pakistan access to antibiotics remains unchecked and hence results in it are over use. The aim of this study was to assess knowledge of parents regarding use of antibiotics, its associated problems, their source of information and their expectations from Paediatricians for prescription of anti-biotics.Methods: This is a questionnaire based cross sectional study conducted in Hayatabad town, District Peshawar. Parents who were consenting, had children aged between 0-16 years, and were …

Organ Transplants For Prisoners: The Incompatibility Of Incarceration And Health Care, Sameer Singh

Student Works

No abstract provided.

Continuous Subglottic Suctioning Of Intubated Patients In The Icu, Dan Deutsch

Physician Assistant Scholarly Project Posters

Ventilator associated pneumonia (VAP) is a common complication in mechanically ventilated patients. It causes substantial morbidity and mortality, as well as substantial cost to the patients and healthcare systems. One of the major risk factors identified for risk of VAP is the aspiration of secretions from the oropharynx. One intervention aimed at decreasing the incidence of secretion aspiration is an endotracheal tube (ETT) that can be hooked up to suction, providing continuous subglottic suctioning. The purpose of this paper was to explore the use of continuous subglottic suctioning and its effects on the incidence of ventilator-associated pneumonia. Review of literature …

Comparing Fecal Microbiota Transplant (Fmt) To Vancomycin: In Treatment Of Recurrent Clostridium Difficile Infections (Cdi), Christopher Seil

Physician Assistant Scholarly Project Posters

• Clostridium difficile infection (CDI) is the main cause of antibiotic-associated pseudomembranous colitis.

• CDI has tripled over the last ten years due to the increased use of broad spectrum antibiotics. CDI has become increasingly difficult to manage with traditional therapies such as metronidazole and vancomycin due to mutations in the pathogen, resulting in resistant organisms.

• The purpose of this review was to determine if fecal microbiota transplantation (FMT) is more effective in treating and curing CDIs than traditional vancomycin therapy.

• The hypothesis was that FMT will have better treatment outcomes than traditional vancomycin therapy.

• The findings …

Lyme Disease Outcomes With Immediate, Short Duration Antibiotic Use Versus Delayed, Longer Duration Use, Lori A. Steinley

Physician Assistant Scholarly Project Posters

Lyme disease is the fastest growing vector-borne disease in the United States, according to the Infectious Disease Society of America (IDSA). The guidelines for diagnosis provided by the IDSA include evidence of erythema migrans rash with validation of a positive two-tier serology testing. With no established treatment standards, decreased sensitivity of testing and inconsistency of observing the rash, practitioners following the guidelines may delay treatment of antibiotics. This delay could cause progression of severity of symptoms.

The purpose of this study is to compare implementation and duration time of antibiotics and establish the treatment protocol for best clinical outcomes for …

Novel Strategies To Develop Better Brucellosis Vaccines Using Brucella Abortus Rb51 And B. Neotomae, Neha Dabral

Open Access Dissertations

The genus Brucella consists of Gram-negative, facultative intracellular coccobacilli that can cause chronic infections in several mammals. Brucella spp. can exhibit a smooth or rough phenotype; smooth Brucella spp. contain a surface-exposed O-polysaccharide in their cell wall structure while the rough Brucella spp. are devoid of the O-polysaccharide. Acquired immunity against Brucella infection is primarily cell-mediated and involves both CD4+ T cells and CD8+ T cell responses. However, antibodies to the O-polysaccharide also play a role in enhancing the protection against infections by virulent Brucella species in some hosts. B. abortus strain RB51 is a stable rough attenuated mutant which …

The Impact Of Down Syndrome And Folate Depletion On Genomic Stabilizing Pathways Of Lymphoblastoid Cells, Khadijah Ibrahim Alnabbat

Wayne State University Theses

Understanding the role of nutrition plays in Down syndrome (DS) could help in the development and implementation of strategies that help overcome the negative consequences phenotypes of Down syndrome. Conserving genome integrity is crucial for cells to survive, and thus understanding how genetic defects induce damage to genomic DNA and impair subsequent repair of this damage is important. Evidence accumulated points to increased DNA damage and mutation accumulation associated with a decline in DNA repair capacity, Base Excision Repair (BER) in particular. Thus, the successful clinical management of DS resides in understanding the metabolic imbalance provoked by overexpression of genes …

Do Tell! The Rights Of Donor-Conceived Offspring, Naomi Cahn

Hofstra Law Review

The article discusses the legal rights of donor-conceived children in America, and it mentions U.S. constitutional rights, the laws associated with donor conception in the country, and the concept of double disclosure. Parental rights and children's interests are mentioned, along with respect for familial autonomy and various aspects of U.S. family and health laws. Sperm and egg (ovum) donations are examined, along with the nation's fertility industry and assisted reproductive technology.

Class Notes

DePaul Magazine

Alumni information from the 1950s through the 2010s; DePaul banner at the University Club of Chicago; and in memoriam listings; Reunion Weekend; Career Week 2014; Blue Demon Day 2014; Alumni & Friends Reception With the President; DePaul Pride photos from around the world

Health And Human Rights, Jonathan Todres

Faculty Publications By Year

No abstract provided.

Ethics Consultations And Conflict Engagement In Health Care, Charity Scott

Faculty Publications By Year

This article explores the intersection of two professional fields - bioethics and clinical ethics consultation in health care on one hand, and alternative dispute resolution ("ADR") and conflict management on the other - which until recent years remained relatively unknown to each other. It marries the literatures and lessons of these two fields in order to promote the quality of ethics consultations in hospitals and other health care organizations. * Increasingly, health care ethics committees and consultants acknowledge the need to employ the frameworks, approaches, and tools of good conflict management to do their work effectively. Similarly, conflict specialists and …

Behavioral Response Of N. Spring Peepers (Pseudacris Crucifer) To A Common Road De-Icer, Nacl, Kara Lindstrom

Theses, Dissertations and Culminating Projects

Amphibians are highly susceptible to environmental degradation in the form of pollution and are therefore considered an indicator for pollutants. Amphibian populations have been on the decline in recent years and possible causes have been subject of much recent research. One possible contributor to the decline is the effect of the use of road de-icing salts on the availability of viable habitat choices. Road salt, primarily NaCl, is one of the leading contributors of chloride in aquatic environments in northern climates. Salt from road run-off has the ability to affect amphibians directly by causing a reduction in offspring fitness, resulting …

High-Level Expression Of The Brugia Malayi Protein Kinase, Bm-Mpk 1, In Insect Sf9 Cells, Arti Rana

Theses, Dissertations and Culminating Projects

Lymphatic Filariasis (elephantiasis) is a neglected tropical disease caused by the filarial nematodes Brugia malayi (B. malayi), Brugia timori, and Wuchererici Bancrofti (1,8). These parasites are present in over 83 counties in the tropics and sub-tropics where more than 1.4 billion people are at risk of infection and 130 million people are presently infected (1,7). Previous work from our lab has led to the identification and expression of a B. malayi stress-activated protein kinase, Bm-MPKl (a human p38/C. elegans PMK-1 ortholog). Bm-MPKl plays an important role in the parasites’ protection against oxidative stress (1), and as such is a potential …

Implementing The Food Safety Modernization Act: An Examination Of The Inequitable Impact Of The Proposed Preventive Controls And Produce Safety Rules, Ben Metzger

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.