Digital Commons Network^™

Polish Healthcare System In Transition - Perceptions Of The Old And New Systems, Paul Puchta

Master of Public Health Program Student Publications

Poland is the largest country in central Europe. During the Second World War (WWII) Poland lost 39% of its physicians. After WWII, Poland fell under Soviet influence. Socialist parties dominated its government until 1989. Poland was the first country from the Soviet block to adopt economic reforms and turn away from centrally planned system.

Poland is presently a stable democracy with a growing economy, and was accepted to the European Union as a full –fledged member in May 2004. Startling results of the population perception of national healthcare system were published in 2013. Polish customers rated current system poorly, giving …

Is Public Health - Dayton & Montgomery County's Level One Food Safety Certification Training Effective?, Matthew M. Tyler

Master of Public Health Program Student Publications

The objective of the culminating experience was to evaluate the effectiveness of Public Health – Dayton & Montgomery County’s (PHDMC) Level One Food Safety Certification class. Pre-training and post-training quiz score data from approximately 692 participants were examined. Paired t-tests were used to evaluate change in scores, overall, on individual questions, and by job responsibility. There was significant improvements in quiz scores both aggregately (20.6%) and also by individual questions, except for question one which assessed how people could become ill from improper food safety. The temperature related questions were answered incorrectly the most but also showed the most improvement. …

Icipe Annual Report 2014, International Centre Of Insect Physiology And Ecology (Icipe)

icipe Annual Reports

No abstract provided.

Undergraduate Research, Scholarship, Creative Activity Awards At Eiu, 1990-2014, Honors College, Eiu

Criterion 4 Documents

No abstract provided.

101 Puppy Mills: A Sampling Of Problem Puppy Mills In The United States, The Humane Society Of The United States

PUPPY MILL INFORMATION

The goal of the report is to inform consumers about widespread problems with puppy mills before they make an uninformed purchase that could potentially support animal cruelty. The report includes puppy mills from 22 states, but because most of the dealers sell online or to pet stores, their puppies could be available to unwary consumers in all 50 states and beyond.

The breeders and sellers on this list represent common issues with puppy mills and puppy mill brokers. This report is not a complete list of all puppy mills, nor a list of all problematic facilities. For more information on …

Biosecurity Challenges Of Industrial Farm Animal Production

Agribusiness Reports

No abstract provided.

Welfare Of Non-Traditional Pets, Catherine A. Schuppli, David Fraser, H. J. Bacon

Wild and Exotic Animals as Pets Collection

The keeping of non-traditional or ‘exotic’ pets has been growing in popularity worldwide. In addition to the typical welfare challenges of keeping more traditional pet species like dogs and cats, ensuring the welfare of non-traditional pets is complicated by factors such as lack of knowledge, difficulties meeting requirements in the home and where and how animals are obtained. This paper uses examples of different species to highlight three major welfare concerns: ensuring that pets under our care i) function well biologically, ii) are free from negative psychological states and able to experience normal pleasures, and iii) lead reasonably natural lives. …

Phasing Out Fossil Fuels, David M. Driesen

Nova Law Review

No abstract provided.

Creating Knowledge, Volume 7, 2014

Creating Knowledge

Dear Students, Faculty Colleagues and Friends, It is my great pleasure to introduce the seventh volume of the College of Liberal Arts and Social Sciences’ Creating Knowledge—our undergraduate student scholarship and research journal. First published in 2008, the journal is the outcome of an initiative to enhance and enrich the academic quality of the student experience within the college. Through this publication, the college seeks to encourage students to become actively engaged in creating scholarship and research and gives them a venue for the publication of their essays.

Beginning with the sixth volume of the journal, we instituted a major …

Retrospective, 2014, University Of Arkansas, Fayetteville. Libraries

Retrospective

No abstract provided.

Application Of Loop-Mediated Isothermal Amplification (Lamp) In Microbiological Water Quality Analysis, Nduta F. Mwangi

All Master’s Theses

Water is life thus access to safe drinking water is essential to health and a basic human right. Kenya is considered a water scarce country whose water sources are becoming more contaminated through changes in land use and poor solid waste management. This has in turn affected the quantity and quality of portable water available. There are nearly 1.7 billion cases of waterborne diarrheal disease every year with over 760 000 deaths of children under five years. Traditional methods of identification of waterborne pathogens are less specific, sensitive, timeconsuming and laborious, so there is a need for the development of …

The Impact Of Movements And Animal Density On Continental Scale Cattle Disease Outbreaks In The United States, Michael Buhnerkempe, Michael J. Tildesley, Tom Lindstrom, Daniel A. Grear, Katie Portacci, Ryan S. Miller, Jason E. Lombard, Marleen Werkman, Matt J. Keeling, Uno Wennergren, Colleen T. Webb

Zoonotics and Wildlife Disease: Publications

Globalization has increased the potential for the introduction and spread of novel pathogens over large spatial scales necessitating continental-scale disease models to guide emergency preparedness. Livestock disease spread models, such as those for the 2001 foot-and-mouth disease (FMD) epidemic in the United Kingdom, represent some of the best case studies of large-scale disease spread. However, generalization of these models to explore disease outcomes in other systems, such as the United States’s cattle industry, has been hampered by differences in system size and complexity and the absence of suitable livestock movement data. Here, a unique database of US cattle shipments allows …

Pathogens At The Livestock-Wildlife Interface In Western Alberta: Does Transmission Route Matter?, Mathieu Pruvot, Susan Kutz, Frank Van Der Meer, Marco Musiani, Herman W. Barkema, Karin Orsel

Zoonotics and Wildlife Disease: Publications

In southwestern Alberta, interactions between beef cattle and free-ranging elk (Cervus elaphus) may provide opportunities for pathogen transmission. To assess the importance of the transmission route on the potential for interspecies transmission, we conducted a cross-sectional study on four endemic livestock pathogens with three different transmission routes: Bovine Viral Diarrhea Virus and Bovine Herpesvirus 1 (predominantly direct transmission), Mycobacterium avium subsp. paratuberculosis (MAP) (indirect fecal-oral transmission), Neospora caninum (indirect transmission with definitive host). We assessed the occurrence of these pathogens in 28 cow-calf operations exposed or non-exposed to elk, and in 10 elk herds exposed or not to cattle. We …

Clinical Features And Genetic Analysis Of 20 Chinese Patients With X-Linked Hyper-Igm Syndrome, Lin-Lin Wang, Wei Zhou, Wei Zhao, Zhi-Qing Tian, Wei-Fan Wang, Xiao-Fang Wang, Tong-Xin Chen

Pediatrics Publications

X-linked hyper-IgM syndrome (XHIGM) is one type of primary immunodeficiency diseases, resulting from defects in the CD40 ligand/CD40 signaling pathways. We retrospectively analyzed the clinical and molecular features of 20 Chinese patients diagnosed and followed up in hospitals affiliated to Shanghai Jiao Tong University School of Medicine from 1999 to 2013. The median onset age of these patients was 8.5 months (range: 20 days–21 months). Half of them had positive family histories, with a shorter diagnosis lag. The most common symptoms were recurrent sinopulmonary infections (18 patients, 90%), neutropenia (14 patients, 70%), oral ulcer (13 patients, 65%), and protracted diarrhea …

Medical Education, Pdas And Smartphones: Welcome To The 21st Century, David P. Paul, Nicole Moussa, Sara Asad, Brad Pershing, Alberto Coustasse

Management Faculty Research

PDAs and Smartphones allow medical professionals to access medical information more easily than ever before. This literature review examines use of these devices and associated “apps” in medical education, finding widespread use by medical students, residents, and faculty. Surprisingly, little generational bias was noted.

Measuring Hiv Stigma At The Family Level: Psychometric Assessment Of The Chinese Courtesy Stigma Scales (Ccsss), Hongjie Liu, Yongfang Xu, Yehuan Sun, Levent Dumenci

Social and Behavioral Sciences Publications

Courtesy stigma is the stigmatization a person perceives or experiences due to their association with a stigmatized individual or group. Most HIV-related stigma scales have been developed for people living with HIV/AIDS (PLWHAs), but not for their HIV-uninfected family members. To date, few measurement scales have been designed to measure the degree of stigma among both PLWHAs and their HIV-uninfected family members at the family level. We developed a set of courtesy stigma scales and estimated their reliability and validity from 256 PLWHAs and 256 of their HIV-uninfected family members. Exploratory and confirmatory factor analyses were performed in two independent …

Functional Evolution Of Plp-Dependent Enzymes Based On Active-Site Structural Similarities, Jonathan Catazaro, Adam Caprez, Ashu Guru, David Swanson, Robert Powers

Holland Computing Center: Faculty Publications

Families of distantly related proteins typically have very low sequence identity, which hinders evolutionary analysis and functional annotation. Slowly evolving features of proteins, such as an active site, are therefore valuable for annotating putative and distantly related proteins. To date, a complete evolutionary analysis of the functional relationship of an entire enzyme family based on active-site structural similarities has not yet been undertaken. Pyridoxal-5’-phosphate (PLP) dependent enzymes are primordial enzymes that diversified in the last universal ancestor. Using the Comparison of Protein Active Site Structures (CPASS) software and database, we show that the active site structures of PLP-dependent enzymes can …

Increasing Chlamydia Retesting Rates In Std Clinics, Michelle L. Bellando

Master of Public Health Program Student Publications

Background: Chlamydia is the most common STD in the United States (Mishori, McClaskey, & WinklerPrins, 2012). Due to the high reinfection rate of Chlamydia, the CDC recommends retesting three months after initial treatment (Park, Amey, Creegan, Barandas, & Bauer, 2010).

Objective: The purpose of this study is to investigate strategies that might improve STD follow-up rates in a clinic setting.

Methods: Public Health - Dayton and Montgomery County STD clinic patients 18 years and older who tested positive for NonGonococcal Urethritis (NGU) or Mucopurulent Cervicitis (MPC) and who agreed to participate were given an opinion survey.

Results: Of the 31 …

Interaction Between Climatic, Environmental, And Demographic Factors On Cholera Outbreaks In Kenya, James D. Stoltzfus, Jane Y. Carter, Muge Akpinar-Elci, Martin Matu, Victoria Kimotho, Mark J. Giganti, Daniel Langat, Omur C. Elsi

Community & Environmental Health Faculty Publications

Background:

Cholera remains an important public health concern in developing countries including Kenya where 11,769 cases and 274 deaths were reported in 2009 according to the World Health Organization (WHO). This ecological study investigates the impact of various climatic, environmental, and demographic variables on the spatial distribution of cholera cases in Kenya.

Methods:

District-level data was gathered from Kenya’s Division of Disease Surveillance and Response, the Meteorological Department, and the National Bureau of Statistics. The data included the entire population of Kenya from 1999 to 2009.

Results:

Multivariate analyses showed that districts had an increased risk of cholera outbreaks when …

Use Of Web-Based Learning Modules For A General Medicine Advanced Pharmacy Practice Experience., Sarah A. Nisly, Alex N. Issacs, Kathryn Givens Merkel

Scholarship and Professional Work – COPHS

Objective. To implement and assess web-based learning modules on baseline pharmacy student knowledge prior to a general medicine advanced pharmacy practice experience (APPE).

Methods. Three web-based learning modules were developed for use prior to a general medicine APPE. Students completed pre- and post-assessments specific to each learning module. Additionally, students completed perception surveys at the conclusion of the APPE to determine the utility of these modules and the impact on student learning experiences.

Results. Use of the web-based training (WBT) modules resulted in a statistically significant improvement in post-assessment scores for two of the three modules (p < 0.001). Student participants found the modules easy to use and helpful in APPE preparation.

Conclusions. Utilization …

Are Elevated Vancomycin Serum Trough Concentrations Achieved Within The First 7 Days Of Therapy Associated With Acute Kidney Injury In Children?, Chad A. Knoderer, Kristen R. Nichols, Kelsey C. Lyon, Megan M. Veverka, Amy C. Wilson

Scholarship and Professional Work – COPHS

Background In 2008, the empiric vancomycin dosing recommendation in children at our institution was changed from 40 to 60 mg/kg per day. Subsequently, an increased incidence of acute kidney injury (AKI) in patients receiving vancomycin was suspected. The objective of this study was to evaluate AKI in children receiving vancomycin and to determine risk factors for AKI development.

Methods Medical records of patients aged 30 days through 17 years who received vancomycin for at least 72 hours between January and December 2007 (40 mg/kg per day) and January and December 2010 (60 mg/kg per day) were reviewed. Patients with cystic …

A Retrospective Comparison Of Daptomycin Thrice-Weekly Versus Q48h Dosing In Hemodialysis Patients With Vancomycin-Resistant Enterococcus (Vre) Or Methicillin-Resistant Staphylococcus Aureus (Mrsa) Bacteremia, Katie L. Axford, Dane L. Shiltz

Scholarship and Professional Work – COPHS

Background. Multi-drug resistant bacteria are a growing concern in healthcare. Daptomycin is being used with increasing frequency in the treatment of vancomycin-resistant enterococci (VRE) and methicillin-resistant Staphylococcus aureus (MRSA) bacteremias in hemodialysis (HD) patients. Thrice-weekly dosing of daptomycin in this population would allow for coordination of dosing with common outpatient HD schedules. The aim of this study is to determine if thrice-weekly dosing of daptomycin is equivalent to dosing every 48 hours in patients receiving chronic intermittent hemodialysis. Equivalence will be assessed with regard to microbiological cure, clinical cure, hospital length of stay, and mortality. Methods. All patients with positive …

Optimized Antimicrobial Dosing Strategies: A Survey Of Pediatric Hospitals, Chad A. Knoderer, Kristen R. Nichols, Elaine G. Cox

Scholarship and Professional Work – COPHS

Background

Extended-interval aminoglycoside (EIAG) and extended- and continuous-infusion β-lactam (EIBL and CIBL) dosing strategies are increasingly used in adults, but pediatric literature is limited.

Objective

The objective of this study was to describe the use of EIAG, EIBL, and CIBL dosing in pediatric hospitals in the USA.

Study Design, Setting, and Participants

A national survey of children’s hospitals was conducted. A single practitioner from each target hospital was identified through the Children’s Hospital Association. Practice-based survey questions identified whether hospitals utilize EIAG, EIBL, and CIBL dosing.

Main Outcome Measure

The main outcome measure was the percentage utilization of the dosing …

Correlation Of Adherence To The 2012 Infectious Diseases Society Of America Practice Guidelines With Patient Outcomes In The Treatment Of Diabetic Foot Infections In An Outpatient Parenteral Antimicrobial Programme, L. M. Pence, C. M. Mock, M. B. Kays, Kendra M. Damer, E. W. Muloma, S. M. Erdman

Scholarship and Professional Work – COPHS

Aim

To evaluate adherence to the 2012 Infectious Diseases Society of America practice guidelines for the management of patients with diabetic foot infections and to determine an association between adherence and clinical outcome.

Methods

A retrospective chart review was performed to evaluate the management and clinical outcomes of patients with diabetic foot infections treated with outpatient parenteral antimicrobial therapy between 1 January 2011 and 30 June 2012 at Wishard Health Services/Eskenazi Health. Adherence to individual Infectious Diseases Society of America diabetic foot infection treatment guideline recommendations was measured, and then assessed in relation to clinical outcome.

Results

A total of …

Broad And Direct Interaction Between Tlr And Siglec Families Of Pattern Recognition Receptors And Its Regulation By Neu1., Guo-Yun Chen, Nicholas K. Brown, Wei Wu, Zahra Khedri, Hai Yu, Xi Chen, Diantha Van De Vlekkert, Alessandra D'Azzo, Pan Zheng, Yang Liu

Pediatrics Faculty Publications

Both pathogen- and tissue damage-associated molecular patterns induce inflammation through toll-like receptors (TLRs), while sialic acid-binding immunoglobulin superfamily lectin receptors (Siglecs) provide negative regulation. Here we report extensive and direct interactions between these pattern recognition receptors. The promiscuous TLR binders were human SIGLEC-5/9 and mouse Siglec-3/E/F. Mouse Siglec-G did not show appreciable binding to any TLRs tested. Correspondingly, Siglece deletion enhanced dendritic cell responses to all microbial TLR ligands tested, while Siglecg deletion did not affect the responses to these ligands. TLR4 activation triggers Neu1 translocation to cell surface to disrupt TLR4:Siglec-E interaction. Conversely, sialidase inhibitor Neu5Gc2en prevented TLR4 ligand-induced …

Graduate Medical Education 2013-2014 Annual Report, Children's Mercy Hospital

GME Annual Reports

Annual report of the Children's Mercy Hospital Graduate Medical Education department, including pediatric residency, internal medicine/pediatrics residency, fellowship programs, medical students, continuing medical education, and library services.

Uncle Sam Knows What’S In Your Medicine Cabinet: The Security And Privacy Protection Of Health Records Under The Hitech Act, 30 J. Marshall J. Info. Tech. & Privacy L. 667 (2014), Ranjit Janardhanan

UIC John Marshall Journal of Information Technology & Privacy Law

No abstract provided.

Repurposing - Finding New Uses For Old (And Patented) Drugs: Bridging The "Valley Of Death," To Translate Academic Research Into New Medicines, Daniel S. Sem

Marquette Intellectual Property Law Review

None.

Ip Policy Forum: Repurposing & Collaborative Drug Development For Rare Diseases, Ramaiah Muthyala

Marquette Intellectual Property Law Review

None.

Winter 2014 Shsp Alumni Connections, New York Medical College

School of Health Sciences and Practice

• NYMC Announces the Appointment of New Dean of the School of Medicine
• Guests Enjoy Elegant Evening at the Founder’s Dinner
• NYMC Launches BioInc@NYMC
• Join Us For the Alumni House 30th Anniversary Celebration
• NYMC Announces Academic Affiliation with Beckley VA Medical Center
• NYMC Hosts Second Annual Drs. Gabor and Harriette Kaley Endowed Lectureship
• D.P.T. Students Run a Successful Race for Rehab and Celebrate National Physical Therapy Month
• Center for Disaster Medicine Provides PPE Training for Ebola
• Pharmacology Research Day Pays Tribute to the late John C. McGiff, M.D.
• NYMC Welcomes Joel Kupersmith, M.D. ’64, Back to Campus for Special Dean’s Lecture …