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December Agenda, Wku Graduate Council

Graduate School

Meeting agenda.

A Tale Of Two Cities: Differences In Wine-Drinking Habits In Nice And London, Lacey S. Gibson

Honors Theses

The French Paradox is the theory that, despite consumption of classically-condoned fatty foods, the French remain in excellent health in comparison with citizens of other nations. This notion has been the subject of worldwide media fascination with publication of a plethora of journal articles and novels. A growing body of evidence supports a role for moderate consumption of wine in conferring health benefits. The role of wine in health may be especially prevalent in the French Riviera, a region whose regime is dominated by the French-Mediterranean Diet. I sought to determine the role of wine in the French Paradox by …

The Role Of Chemokine Receptor Cxcr7 With Egfr In Breast Cancer Cell Proliferation, Nicole Salazar

Open Access Dissertations

Recent advances have revealed a significant contribution of chemokines and their receptors in tumor growth, survival after chemotherapy and organ-specific metastasis. The CXC chemokine receptor-7 (CXCR7) is the latest chemokine receptor implicated in cancer. Although over expressed in breast cancer cell lines and tumor tissues, its mechanism of action in breast cancer (BrCa) growth and metastasis was not clear. Studies in other cancers have implicated CXCR7 in cell proliferation, anti-apoptotic activity and cell-cell adhesion. The present study was initiated to examine the pattern of CXCR7 expression and its role in regulation of growth signaling in breast cancer. The contribution of …

Genome-Wide Analysis Of Drosophila Circular Rnas Reveals Their Structural And Sequence Properties And Age-Dependent Neural Accumulation, Sarah Olson, Brenton R. Graveley

UCHC Articles - Research

Circularization was recently recognized to broadly expand transcriptome complexity. Here, we exploit massive Drosophila total RNA-sequencing data, >5 billion paired-end reads from >100 libraries covering diverse developmental stages, tissues, and cultured cells, to rigorously annotate >2,500 fruit fly circular RNAs. These mostly derive from back-splicing of protein-coding genes and lack poly(A) tails, and the circularization of hundreds of genes is conserved across multiple Drosophila species. We elucidate structural and sequence properties of Drosophila circular RNAs, which exhibit commonalities and distinctions from mammalian circles. Notably, Drosophila circular RNAs harbor >1,000 well-conserved canonical miRNA seed matches, especially within coding regions, and coding …

Physical Therapy Management Of A Patient After A Subacromial Decompression With Acromioplasty And Bursectomy: A Case Report, Brianne Landholt

Case Report Posters

Background: Subacromial impingement results from repetitive trauma to structures underneath the subacromial arch which can lead to: A decrease in the subacromial space, impingement of the soft tissue, a decrease in functional abilities. Conservative treatment can include: Physical therapy, nonsteroidal anti-inflammatory drugs (NSAIDS), corticosteriod injections, surgical option includes a subacromial decompression (SAD). There is conflicting evidence on the benefits of surgery. Literature is lacking supportive evidence of SAD without RTC repair or performing SAD with both an acromioplasty and bursectomy. Purpose: The purpose of this case report was to investigate the functional outcomes of a patient after SAD with an …

Physical Therapy Management Of A Manual Laborer With Chronic Rotator Cuff Tendinopathy: A Case Report, Samuel Lasher

Case Report Papers

Background and Purpose: Rotator cuff tendinopathy (RCT) is a chronic tendon injury that can have significant impact on an individual’s occupation, recreation and personal life. Currently there is a paucity of information detailing physical therapy (PT) interventions for individuals with RCT, who must continue working. The purpose of this case report was to report a clinical experience detailing the PT management of a patient with RCT, who secondary to occupational obligations must continue to participate in activities harmful to her condition. Case Description: The patient was a 44 year-old, female, who worked as a manual laborer. She was diagnosed with …

Physical Therapy Management Of A Patient With Stroke Utilizing Muscular Facilitation Techniques In A Skilled Nursing Facility: A Case Report, Erin Bayne

Case Report Papers

Background and Purpose: Stroke is the leading cause of long term disability in the United States. Hemiparesis is an impairment following stroke, however trunk musculature asymmetry is also common and is often overlooked when assessing a patient’s muscular control. Trunk musculature is an essential link between the upper and lower extremities during activities of daily living and impairments in trunk musculature can result in decreased safety and balance. The purpose of this case report is to provide the framework for treatment and an overview of the care plan for a patient following stroke, with special attention to trunk musculature facilitation. …

The Role And Impact Of Student Leadership On Participants In A Healthy Eating And Physical Activity Programme, Lila Gutuskey, Nate Mccaughtry, Bo Shen, Erin Centeio, Alex Garn

Kinesiology, Health and Sport Studies

Objective: In the USA there are rising rates of obesity among children, at least in part due to unhealthy eating and physical inactivity. Implementing school-based health interventions with elementary school children focused on youth empowerment could lead to improved health environments and behaviours. The purpose of the present study was to examine elementary students’ perceptions of participating in a student-led school health improvement team. Empowerment theory guided the research, specifically the concept of including participants in programming to identify possible individual-level outcomes. Design: Qualitative research. Setting: One US elementary school formed a student-led school health improvement team, …

Higher-Order Targeted Minimum Loss-Based Estimation, Marco Carone, Iván Díaz, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Common approaches to parametric statistical inference often encounter difficulties in the context of infinite-dimensional models. The framework of targeted maximum likelihood estimation (TMLE), introduced in van der Laan & Rubin (2006), is a principled approach for constructing asymptotically linear and efficient substitution estimators in rich infinite-dimensional models. The mechanics of TMLE hinge upon first-order approximations of the parameter of interest as a mapping on the space of probability distributions. For such approximations to hold, a second-order remainder term must tend to zero sufficiently fast. In practice, this means an initial estimator of the underlying data-generating distribution with a sufficiently large …

12-11-2014 Swosu Alumni Association Adds Six New Directors, Southwestern Oklahoma State University

THE BARK ARCHIVE 2014

Six outstanding graduates of Southwestern Oklahoma State University in Weatherford have been named to the SWOSU Alumni Association Board of Directors.

The South Has Not Risen In Nhl Attendance Numbers Compared To The North, Kyle Stich

Sport Management Undergraduate

This research looked at attendance capacity for traditional and non-traditional hockey markets. The aim was to attempt to determine the extent the attendance capacities differed between the two markets. Previously, there had not been any quantitative analyses done comparing traditional and non-traditional hockey markets so this study aimed to add new knowledge to that area. The National Hockey League (NHL) grapples with the validity of some of the current markets, with many observers calling for some teams to relocate to new markets. This research aimed to attempt to determine how justified those criticisms were.

Kim, Trail, & Magnusen (2013) have …

P53 And Cancer-Associated Sialylated Glygans Are Surrogate Markers Of Cancerization Of The Bladder Associated With Schistosoma Haematobium Infection, Julio Santos, Elisabete Fernandes, Jose Alexandre Ferreira, Luis Lima, Ana Tavares, Andreia Peixoto, Beatriz Parreira, Jose Manuel Correia Da Costa, Paul J. Brindley, Carlos Lopes, Lucio L. Santos

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly understood. Bladder cancers in infected populations are generally diagnosed at a late stage since there is a lack of non-invasive diagnostic tools, hence enforcing the need for early carcinogenesis markers.

Methodology/Principal Findings

Forty-three formalin-fixed paraffin-embedded bladder biopsies of S. haematobium-infected patients, consisting of bladder tumours, tumour adjacent mucosa and pre-malignant/malignant urothelial lesions, were screened for bladder …

Fit To Focus: Measuring The Effects Of Physical Activity On Behavior Management, Kaylee Vaughan

Education Undergraduate Research

No abstract provided.

The Public Health Exposome: A Population-Based, Exposure Science Approach To Health Disparities Research, Paul D. Juarez, Patricia Matthews-Juarez, Darryl B. Hood, Wansoo Im, Robert S. Levine, Barbara J. Kilbourne, Michael A. Langston, Mohammad Z. Al-Hamdan, William L. Crosson, Maurice G. Estes, Sue M. Estes, Vincent K. Agboto, Paul Robinson, Sacoby Wilson, Maureen Y. Lichtveld

Sociology Faculty Research

The lack of progress in reducing health disparities suggests that new approaches are needed if we are to achieve meaningful, equitable, and lasting reductions. Current scientific paradigms do not adequately capture the complexity of the relationships between environment, personal health and population level disparities. The public health exposome is presented as a universal exposure tracking framework for integrating complex relationships between exogenous and endogenous exposures across the lifespan from conception to death. It uses a social-ecological framework that builds on the exposome paradigm for conceptualizing how exogenous exposures “get under the skin”. The public health exposome approach has led our …

The Principle Of Reciprocity In Hospitality Contexts: The Relationship Between Tipping Behavior And Food Servers’ Approaches To Handling Leftovers, John S. Seiter, Harry Weger

Languages, Philosophy, and Communication Studies Faculty Publications

Based on the norm of reciprocity, this study hypothesized that food servers would earn higher tips when they boxed customers’ leftovers compared to having customers box leftovers themselves. In addition, the effect of writing messages (i.e., the date and/or customer’s name) on boxes of leftovers was explored. Two female food servers waited on 608 diners and boxed or did not box leftovers, and wrote or did not write messages on boxes. The hypothesis was supported. However, writing messages was not associated with tipping behavior.

Vol.42 N.20 December 11th 2014, Voice Media Ventures

Black Voice News

No abstract provided.

Examination Of Capital Murder Jurors’ Deliberations: Methods And Issues, Keith Price, Susan Coleman, Gary R. Byrd

Administrative Issues Journal

The study of capital juries remains a subject of critical interest for the public and for legislative and judicial policy makers as well as legal scholars and social scientists. Cowan, Thompson, and Ellsworth established one of the standard methodologies for examination of this topic in their 1984 seminal study by observing the subjects’ debate about conviction in a death penalty case utilizing mock juries; other scholars employed different techniques to add more information in the late 1990s. Yet, the question of death qualification and prosecutorial bias remains open to inquiry. This preliminary study found evidence to support bias toward conviction …

Physical Therapy Management Of A Manual Laborer With Chronic Rotator Cuff Tendinopathy: A Case Report, Samuel Lasher

Case Report Posters

Background: Tendinopathy is characterized by tendon thickening, localized pain and chronic degeneration reflective of failed healing. 38% of manual laborers who participate in daily moderate to heavy lifting will experience Rotator Cuff Tendinopathy(RCT). There is a lack of research investigating the PT management of manual laborers who have RCT, but must continue to participate in harmful activities to fulfill occupational responsibilities. Purpose: The purpose of this case report was to describe the PT management of a patient with rotator cuff tendinopathy who, due to work requirements continued to participate in activities detrimental to the health of the supraspinatus and function …

Expression Of Suppressor Of Cytokine Signaling 1 (Socs1) Impairs Viral Clearance And Exacerbates Lung Injury During Influenza Infection., Keer Sun, Sharon Salmon, Vijaya Kumar Yajjala, Christopher Bauer, Dennis W. Metzger

Journal Articles: Pathology and Microbiology

Suppressor of cytokine signaling (SOCS) proteins are inducible feedback inhibitors of cytokine signaling. SOCS1-/- mice die within three weeks postnatally due to IFN-γ-induced hyperinflammation. Since it is well established that IFN-γ is dispensable for protection against influenza infection, we generated SOCS1-/-IFN-γ-/- mice to determine whether SOCS1 regulates antiviral immunity in vivo. Here we show that SOCS1-/-IFN-γ-/- mice exhibited significantly enhanced resistance to influenza infection, as evidenced by improved viral clearance, attenuated acute lung damage, and consequently increased survival rates compared to either IFN-γ-/- or WT animals. Enhanced viral clearance in SOCS1-/-IFN-γ-/- mice coincided with a rapid onset of adaptive immune …

Exploring The Intersection Between Folk And Conventional Medicine In Albany, Kentucky, Chloe J. Brown

Mahurin Honors College Capstone Experience/Thesis Projects

Approximately 60% of patients surveyed (in Albany, KY) practice folk medicine, which suggests that a significant segment of the population may practice folk medicine. Patients typically use folk medical treatments concurrently with conventional medical treatments; while the interaction of these treatments is generally innocuous or positive, folk medical treatments can sometimes be harmful, lead to negative interactions with other drugs prescribed by a conventional medical professional. Since folk medicine and conventional medicine frequently interact, it is important for medical professionals to be aware of and address folk medical practices in a conventional medical environment. In order to better address folk …

Academic Standards Subcommittee Agenda, December 11, 2014, Utah State University

Educational Policies Committee

• International Baccalaureate Organization (IBO) Awarding of Credit Policy
• Excused Absence Policy

Hip Fracture Evaluation With Alternatives Of Total Hip Arthroplasty Versus Hemiarthroplasty (Health): Protocol For A Multicentre Randomised Trial, Mohit Bhandari, P. J. Devereaux, Thomas A. Einhorn, Lehana Thabane, Emil H. Schemitsch, Kenneth J. Koval, Frede Frihagen, Rudolf W. Poolman, Kevin Tetsworth, Ernesto Guerra-Farfán, Kim Madden, Sheila Sprague, Gordon Guyatt, Ali Oliasharazi, Franklin D. Shuler, Jonathon Salva, James Day, Tigran Garabekyan, Felix Cheung, Linda Morgan, Timothy Wilson-Byrne Md, Mary Beth Cordle

Orthopaedics

Introduction: Hip fractures are a leading cause of mortality and disability worldwide, and the number of hip fractures is expected to rise to over 6 million per year by 2050. The optimal approach for the surgical management of displaced femoral neck fractures remains unknown. Current evidence suggests the use of arthroplasty; however, there is lack of evidence regarding whether patients with displaced femoral neck fractures experience better outcomes with total hip arthroplasty (THA) or hemiarthroplasty (HA). The HEALTH trial compares outcomes following THA versus HA in patients 50 years of age or older with displaced femoral neck fractures.

Methods and …

Functional Lung Avoidance For Individualized Radiotherapy (Flair): Study Protocol For A Randomized, Double-Blind Clinical Trial., Douglas A Hoover, Dante Pi Capaldi, Khadija Sheikh, David A Palma, George B Rodrigues, A Rashid Dar, Edward Yu, Brian Dingle, Mark Landis, Walter Kocha, Michael Sanatani, Mark Vincent, Jawaid Younus, Sara Kuruvilla, Stewart Gaede, Grace Parraga, Brian P Yaremko

Medical Biophysics Publications

BACKGROUND: Although radiotherapy is a key component of curative-intent treatment for locally advanced, unresectable non-small cell lung cancer (NSCLC), it can be associated with substantial pulmonary toxicity in some patients. Current radiotherapy planning techniques aim to minimize the radiation dose to the lungs, without accounting for regional variations in lung function. Many patients, particularly smokers, can have substantial regional differences in pulmonary ventilation patterns, and it has been hypothesized that preferential avoidance of functional lung during radiotherapy may reduce toxicity. Although several investigators have shown that functional lung can be identified using advanced imaging techniques and/or demonstrated the feasibility and …

Identifying Which Patients With Asymptomatic Carotid Stenosis Could Benefit From Intervention, Kosmas I. Paraskevas, J. David Spence, Frank J. Veith, Andrew N. Nicolaides

Department of Medicine Publications

No abstract provided.

Guatemalan Government Mired In Financial Problems, Louisa Reynolds

NotiCen

No abstract provided.

Gw Health Workforce Research Center: Year 1 Results, Leighton Ku, Patricia Pittman, Leah E. Masselink, Bianca K. Frogner

Health Workforce Speaker Series

No abstract provided.

Ifn-Γ Causes Aplastic Anemia By Altering Hematopoietic Stem/Progenitor Cell Composition And Disrupting Lineage Differentiation, Fan Ching Lin, Megan Karwan, Bahara Saleh, Deborah L. Hodge, Tim Chan, Kimberly C. Boelte, Jonathan R. Keller, Howard A. Young

United States Public Health Resources

Aplastic anemia (AA) is characterized by hypocellular marrow and peripheral pancytopenia. Because interferon gamma (IFN-γ) can be detected in peripheral blood mononuclear cells of AA patients, it has been hypothesized that autoreactive T lymphocytes may be involved in destroying the hematopoietic stem cells. We have observed AA-like symptoms in our IFN-γ adenylate-uridylate-rich element (ARE)-deleted (del) mice, which constitutively express a low level of IFN-γ under normal physiologic conditions. Because no T-cell autoimmunity was observed, we hypothesized that IFN-γ may be directly involved in the pathophysiology of AA. In these mice, we did not detect infiltration of T cells in bone …

Changes In Coral Community Composition At Devil's Crown, Galapagos Islands, Ecuador: A 7,700 Year Perspective, Katharine Jane Hendrickson

HCNSO Student Theses and Dissertations

Coral mortality caused by El Niño–Southern Oscillation (ENSO) activity and its related disturbances has been researched throughout the Eastern Pacific. In the past three decades, disturbances related to the El Niño–Southern Oscillation (ENSO) have been shown to influence coral growth in the Eastern Pacific. In the Galápagos Islands, Ecuador, more than 97% of corals experienced mortality after the severe 1982-1983 ENSO episode. However, two of the most dominant coral species found in a coral community adjacent to Devil’s Crown; Psammocora stellata and Diaseris distorta survived this severe ENSO event. By reconstructing sediment cores of the coral community, this study assessed …

Seven Faculty Awarded Emeritus Status, Natalie Wade

Browse All News

No abstract provided.

Faculty Senate Meeting Minutes December 11, 2014, University Of Rhode Island Faculty Senate

Faculty Senate Meeting Minutes

No abstract provided.