Digital Commons Network^™

Greater Professional Empathy Leads To Higher Agreement About Decisions Made In The Consultation, Tracey Parkin, Looy A De, Paul Farrand

School of Health Professions

No abstract provided.

Public Perceptions Of Sharks: Gathering Support For Shark Conservation, Laura A. Friedrich, Rebecca Jefferson, Gillian Glegg

School of Biological and Marine Sciences

No abstract provided.

Comparison Of Intermittent And Continuous Exposures To Inorganic Mercury In The Mussel, Mytilus Edulis: Accumulation And Sub-Lethal Physiological Effects., D Amachree, Aj Moody, Rd Handy

School of Biological and Marine Sciences

Aquatic organisms are often subject to intermittent exposure to pollutants in real ecosystems. This study aimed to compare mercury accumulation and the physiological responses of mussels, Mytilus edulis during continuous and intermittent exposure to the metal. Mussels were treated in a semi-static, triplicated design to either a control (no added Hg) or 50 µg l(-1) Hg as HgCl2 in continuous (daily) or intermittent (2 day exposure, 2 days in clean seawater alternately) exposure for 14 days. A time-dependent increase in Hg accumulation was observed in the continuous exposure, while the intermittent treatment showed step-wise changes in Hg concentrations with the …

Effects Of Dietary Β-(1,3)(1,6)-D-Glucan Supplementation On Growth Performance, Intestinal Morphology And Haemato-Immunological Profile Of Mirror Carp (Cyprinus Carpio L.)., H. Kühlwein, D. L. Merrifield, M. D. Rawling, A. D. Foey, S. J. Davies

School of Biological and Marine Sciences

In recent years, aquaculture research has focused on probiotics, prebiotics, and β-glucans, in order to improve health status and growth performance. Information regarding the effects of β-glucan on growth performance and intestinal immunity of mirror carp (Cyprinus carpio L.) is scarce. An experiment was therefore conducted to investigate the effects of a yeast β-glucan preparation (MacroGard(®) ) on growth performance, intestinal morphology and haemato-immunological indices of mirror carp. Carp (initial weight 11.1 ± 0.0 g) were fed highly purified diets supplemented with 0% (control), 0.1%, 1% or 2% MacroGard(®) for 8 weeks. Fish fed diets containing 1% and 2% MacroGard(®) …

Factors Affecting The Levels Of Protection Transferred From Mother To Offspring Following Immune Challenge, Christina M. Coakley, Vincent Staszewski, Katherine A. Herborn, Emma J.A. Cunningham

School of Biological and Marine Sciences

No abstract provided.

Brain-Computer Music Interfacing: Interdisciplinary Research At The Crossroads Of Music, Science And Biomedical Engineering, Er Miranda

School of Art, Design and Architecture

No abstract provided.

A Descriptive Exploratory Study Of How Admissions Caused By Medication-Related Harm Are Documented Within Inpatients’ Medical Records, Matthew Reynolds, Mary Hickson, Ann Jacklin, Bryony Dean Franklin

School of Health Professions

No abstract provided.

Receptor Of Advanced Glycation Endproducts (Rage) Is Positively Correlated With Tumor Necrosis Factor-Α In Adolescents With Obesity, Tasnim Rahman, Daniel H. Conrad, Anshu Gupta

UROP Posters

Introduction: Obesity in childhood is associated with an increased prevalence of diabetes and other traditional cardiometabolic risk factors, suggesting an epidemic of premature cardiovascular disease among today’s youth. Glycotoxins, known as advanced glycationend products (AGE’s), activating via the membrane-bound receptors (mRAGE), have been implicated in the pathophysiology of inflammation, (increased tumor necrosis factor-α [TNF-α ]), insulin resistance and vascular dysfunction in adults, but the role of RAGE in the early stages of metabolic disorders is unknown. In this study, we assessed relationship of cardiometabolicrisk factors, mRNA expression of TNF-α and RAGE in peripheral monocytes in adolescents with obesity.

Methods: Thirty …

Disordered Eating From Interpersonal Relationships And Body Comparisons, Taylor L. Dawson

UROP Posters

The purpose of this paper is to discuss how women's relationships (with sisters, mothers, female friends and significant others) along with thin ideal media shape beauty ideals and contribute to eating disorders. I studied scholarly articles pertaining to exposure to underweight and healthy weight models and its effect on women. I also examined articles that discussed different types of comparisons that women made on themselves against the female figures in their lives. I examined studies on parental disordered eating and perceived body image. My preliminary conclusion is that women's comparisons in their interpersonal relationships have more of an effect on …

Aftermath Of The Hobby Lobby Decision: Implications For Women In The Workforce, Hirsh Shah

UROP Posters

Burwell v. Hobby Lobby Stores, Inc. is a landmark Supreme Court case in which it was ruled that the contraceptive mandate from the Affordable Care Act was an unnecessary and substantial burden on Hobby Lobby’s corporate exercise of religious freedom. This is the latest of many court cases that have expanded corporation’s rights to equal those of humans, giving them individual status without the responsibilities that come along with it. By citing religious liberty rights, closely held corporations such as Hobby Lobby can impose their religious viewpoints on their employees, specifically by not providing certain contraceptive care coverage. Other corporations …

Integrating Phage Therapy Into Western Medicine, Jacob B. Jaminet

UROP Posters

The World Health Organization has described the rise of antibiotic use as a “global heath security emergency” (who.int). With the growing concern about antibiotic resistant bacteria, there has been an increased interest in bacteriophages. Bacteriophages are high-specific viruses that only infect bacteria. The use of bacteriophages medicinally to treat bacteria is called phage therapy. Research in phage therapy gained momentum until the introduction of antibiotics. While the USA and other Western countries accepted antibiotics, the Soviet Union and their satellite nations still continued to research phages. Since the funding for research was supplied by the Soviet military, the results of …

Minimal Effects Of Waterborne Exposure To Single-Walled Carbon Nanotubes On Behaviour And Physiology Of Juvenile Rainbow Trout (Oncorhynchus Mykiss)., D Boyle, Je Fox, Jm Akerman, Ka Sloman, Tb Henry, Rd Handy

School of Biological and Marine Sciences

Fish behaviours are often considered to be sensitive endpoints of waterborne contaminants, but little attention has been given to engineered nanomaterials. The present study aimed to determine the locomotor and social behaviours of rainbow trout (Oncorhynchus mykiss) during waterborne exposure to single-walled carbon nanotubes (SWCNTs), and to ascertain the physiological basis for any observed effects. Dispersed stock suspensions of SWCNTs were prepared by stirring in sodium dodecyl sulphate (SDS), an anionic surfactant, on an equal w/w basis. Trout were exposed to control (no SWCNT or SDS), 0.25 mg L(-1) SDS (dispersant control), or 0.25 mg L(-1) of SWCNT for 10 …

Uptake Epithelia Behave In A Cell-Centric And Not Systems Homeostatic Manner In Response To Zinc Depletion And Supplementation, D Zheng, Gp Feeney, Rd Handy, C Hogstrand, P Kille

School of Biological and Marine Sciences

No abstract provided.

Effects Of Silver Nanoparticles (Nm-300k) On Lumbricus Rubellus Earthworms And Particle Characterization In Relevant Test Matrices Including Soil, Der Ploeg Mjc Van, Rd Handy, Pl Waalewijn-Kool, Den Berg Jhj Van, Zeh Rivera, J Bovenschen, B Molleman, Jm Baveco, P Tromp, Rjb Peters, Gf Koopmans, Imcm Rietjens, Den Brink Nw Van

School of Biological and Marine Sciences

No abstract provided.

Moving Beyond Too Little, Too Late: Managing Emerging Infectious Diseases In Wild Populations Requires International Policy And Partnerships, Jamie Voyles, A. Marm Kilpatrick, James P. Collins, Matthew C. Fisher, Winifred F. Frick, Hamish Mccallum, Craig K.R. Willis, David S. Blehert, Kris A. Murray, Robert Puschendorf, Erica Bree Rosenblum, Benjamin M. Bolker, Tina L. Cheng, Kate E. Langwig, Daniel L. Lindner, Mary Toothman, Mark Q. Wilber, Cheryl J. Briggs

School of Biological and Marine Sciences

Emerging infectious diseases (EIDs) are on the rise due to multiple factors, including human facilitated movement of pathogens, broad-scale landscape changes, and perturbations to ecological systems (Jones et al. 2008; Fisher et al. 2012). Epidemics in wildlife are problematic because they can lead to pathogen spillover to new host organisms, erode biodiversity and threaten ecosystems that sustain human societies (Fisher et al. 2012; Kilpatrick 2011). There have been recent calls for large-scale research approaches to combat the threats EIDs pose to wildlife (Sleeman 2013). While it is true that developing new analytical models, diagnostic assays and molecular tools will significantly …

Steps Toward A Shared Governance Response For Achieving Good Environmental Status In The Mediterranean Sea, Sergio Cinnirella, R Sarda, Suarez De Vivero J Luis, Ruth Brennan, Alberto Barausse, John Icely, Tiziana Luisetti, David March, Carla Murciano, Alice Newton, T O'Higgins, Luca Palmeri, Maria Giovanna Palmieri, Pascal Raux, Sian Rees, J Albaiges, Nicola Pirrone, Kerry Turner

School of Biological and Marine Sciences

No abstract provided.

The Deep Sea Is A Major Sink For Microplastic Debris, Lucy C. Woodall, Anna Sanchez-Vidal, Miquel Canals, Gordon L.J. Paterson, Rachel Coppock, Victoria Sleight, Antonio Calafat, Alex D. Rogers, Bhavani E. Narayanaswamy, Richard C. Thompson

School of Biological and Marine Sciences

Marine debris, mostly consisting of plastic, is a global problem, negatively impacting wildlife, tourism and shipping. However, despite the durability of plastic, and the exponential increase in its production, monitoring data show limited evidence of concomitant increasing concentrations in marine habitats. There appears to be a considerable proportion of the manufactured plastic that is unaccounted for in surveys tracking the fate of environmental plastics. Even the discovery of widespread accumulation of microscopic fragments (microplastics) in oceanic gyres and shallow water sediments is unable to explain the missing fraction. Here, we show that deep-sea sediments are a likely sink for microplastics. …

Methodologies To Assess Muscle Co-Contraction During Gait In People With Neurological Impairment – A Systematic Literature Review, Mcn Rosa, A Marques, S Demain, Cd Metcalf, J Rodrigues

School of Health Professions

No abstract provided.

Climate Change And Environmental Justice: Lessons From The California Lawsuits, Alice Kaswan

San Diego Journal of Climate & Energy Law

This essay does not debate the political wisdom of suing; instead, it takes the suits as a given and attempts to enhance understanding of the environmental justice community’s climate justice agenda. It describes the role of environmental justice in the development of California’s climate law, AB 32, describes the lawsuits, and suggests some of the larger lessons about climate policy, cap-and-trade, and environmental justice that these lawsuits reveal. Ultimately, the environmental justice lawsuits highlight two primary themes: (1) the importance of a holistic approach to climate change policy that recognizes and integrates its multiple dimensions, including co-pollutant implications; and (2) …

Electric Power Resource "Shuffling" And Subnational Carbon Regulation: Looking Upstream For A Solution, Jim Rossi, Andrew J.D. Smith

San Diego Journal of Climate & Energy Law

The potential for shuffling in wholesale power markets thwarts California’s ability to meet its AB 32 GHG emission reduction goals, and may even lead to emissions increases. Yet, as California’s efforts illustrate, resource shuffling is extremely difficult to regulate at the state level. Short of California aggressively reducing its emissions limits to reflect the leakage problem of shuffling, the state is incapable of solving the problem on its own.
As states follow California’s lead in crafting their own approaches to regulating GHG emissions, national solutions will be necessary to address the problem of resource shuffling, given interstate markets in wholesale …

Carbonite Legal Conflict In California, Steven Ferrey

San Diego Journal of Climate & Energy Law

This Article thaws several legal layers of California carbonite, tranche- by-tranche, and examines the legal fabric. First, in Section II we examine federal Constitutional challenges to California’s A.B. 32 and sustainable energy statutes under the Supremacy Clause. Section III analyzes litigation against California carbon control pursuant to the Commerce Clause of the Constitution. Section IV analyzes challenges to the California regulation pursuant to state law violations, distinguishing those which proceed from the California Environmental Quality Act (CEQA) and those which utilize other state administrative laws to challenge California’s carbon choices and implementation. Section V examines the trilogy of litigation set …

Energy Policy, Extraterritoriality, The Dormant Commerce Clause, Alexandra B. Klass, Elizabeth Henley

San Diego Journal of Climate & Energy Law

This Article will focus specifically on potential challenges to state energy policy based on the “extraterritoriality doctrine” of the dormant Commerce Clause. In doing so, it considers two recent lawsuits involving dormant Commerce Clause challenges to state energy policy. The first is the lawsuit against the State of California over its Low Carbon Fuels Standard (LCFS) program on grounds that it discriminates against Midwest ethanol producers in favor of California ethanol producers and regulates extraterritorially in violation of the dormant Commerce Clause. The second is the lawsuit by the State of North Dakota, the North Dakota lignite coal industry, and …

She Sells Seawalls Down By The Seashore, Tricia Lee

San Diego Journal of Climate & Energy Law

This Comment argues that a bill similar to Assembly Bill 2943 should be proposed today because there has been a drastic shift towards a general acceptance of global warming since 2002. In addition, new environmental studies support the idea of curbing seawall construction along the California coast.

Section I will provide data regarding rising sea levels and the current state of seawall construction along the California coast. It will then explain why seawall construction is not a viable adaptation strategy and delve into its negative social, environmental, and economic impacts.

Section II will examine California’s current policies for protecting coastal …

The Lacey Act Amendments Of 2008: The World's First Ban On Illegal Logging Combats Deforestation But Gets Stumped By Foreign Laws, Yijin J. Lee

San Diego Journal of Climate & Energy Law

By exploring the history of the United States’ legislative efforts in dealing with the problems deforestation has caused and the origins of the Lacey Act, it is possible to understand the inspiration behind the 2008 amendments to the act. Further, exploring the minute details of the Lacey Act amendments and understanding how the amendments have changed the power and meaning behind the original Lacey Act highlights the amendments’ strengths and weaknesses. Also, in understanding how the new amendments are being implemented and enforced, it is possible to see which federal agencies are putting force behind the words of the Lacey …

Jms At 50: Trends Over Time, Timothy Adrian Robert Clark, Mike Wright, Zilia Iskaujina, Philip Garnett

Research Collection Lee Kong Chian School Of Business

We present an analysis of the articles published in the Journal of Management Studiessince its inception to assess to what extent JMS has: maintained its leading international ranking; maintained its founding mission as a broad based management journal; and remained a broad based management journal compared to other general management journals. In terms of its impact factor and citations despite reaching a low point in 2001, we find that JMS today ranks higher than it has ever done throughout its 50‐year history. From our content analysis covering the life‐cycle of JMS, we find four areas have been the most frequently …

Fault-Tolerant Trajectory Tracking Of Unmanned Aerial Vehicles Using Immunity-Based Model Reference Adaptive Control, Brenton K. Wilburn

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation presents the design, development, and simulation testing of an adaptive trajectory tracking algorithm capable of compensating for various aircraft subsystem failures and upset conditions. A comprehensive adaptive control framework, here within referred to as the immune model reference adaptive control (IMRAC) algorithm, is developed by synergistically merging core concepts from the biologically- inspired artificial immune system (AIS) paradigm with more traditional optimal and adaptive control techniques. In particular, a model reference adaptive control (MRAC) algorithm is enhanced with the detection and learning capabilities of a novel, artificial neural network augmented AIS scheme. With the given modifications, the MRAC …

Visible Light Mediated Intermolecular [3 + 2] Annulation Of Cyclopropylanilines With Alkynes, Theresa H. Nguyen, Soumitra Maity, Nan Zheng

Chemistry & Biochemistry Faculty Publications and Presentations

Intermolecular [3 + 2] annulation of cyclopropylanilines with alkynes is realized using visible light photoredox catalysis, yielding a variety of cyclic allylic amines in fair to good yields. This method exhibits significant group tolerance particularly with heterocycles. It can also be used to prepare complex heterocycles such as fused indolines.

Life Transitions In America, Francesco Duina

All Faculty Scholarship

No abstract provided.

The Use Of Hand Bacteria As A Human Biometric Identifier, Amanda Holbert

Graduate Theses, Dissertations, and Problem Reports (ETD)

Molecular and bio-molecular biometrics are an advancing field that involves the analysis of a person's unique biological markers at a molecular level to ascertain identity. Bacteria communities found on the skin of the human hand have shown to be highly diverse and to have a low percentage of similarity between individuals. The goal of this research effort is to see if a person's demographics, primarily ethnicity, share a relationship with the bacteria communities that exist on their hand. A sample collection was carried out in which the left and right inner palms of 250 individuals were swabbed to obtain a …

An Overview Of Acute Myeloid Leukemia And Cancer Immunology: (I) Concepts And Therapeutic Strategies And (Ii) Repsox As A Candidate Cell-Engineering Tool, Audrey Nadine Jajosky

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation is intentionally broad in scope and describes the conceptual frameworks, research advances, and clinical successes that inspired a therapeutic vision that, in turn, prompted specific RepSox experiments (Jajosky, 2014). The goal of this dissertation is to guide and encourage students interested in engineering anti-cancer immune therapies by providing perspective and suggestions. Chapter I provides background on acute myeloid leukemia (AML), the cancer stem cell (CSC) theory, and the chemical reprogramming tool "RepSox." Chapter II describes how tumor cells passively evade immune recognition and actively suppress immune cells to escape destruction. Immunotherapeutic strategies are described that increase tumor-cell immunogenicity …