Digital Commons Network^™

Determining Dna Damage Prevention Mechanisms For Multifunctional Selenium And Sulfur Antioxidants And The Dna-Damaging Capabilities Of Clotrimadozle And Pseudoephedrine-Derived Metal Complexes, Matthew Todd Zimmerman

All Dissertations

DNA damage by reactive oxygen species (ROS) is a cause of many chronic diseases. This work examines the ability of sulfur and selenium antioxidants to prevent oxidative DNA damage and the mechanisms for this activity. Although iron- and copper-generated hydroxyl radical are primary causes of damage under oxidative stress conditions, studies typically focus on ROS scavenging rather than antioxidant-metal binding as a mechanism for sulfur and selenium antioxidant behavior. Mass spectrometry studies of sulfur and selenoamino acids (Chapter 2) show that most form CuI and FeII complexes, regardless of their metal-mediated DNA damage prevention abilities. Because their electrochemical properties do …

Perceived Health Status, Health Values And Health Goals As Influences On Individual Pursuit Of Dtc Genome Testing: Implications For Healthcare Of Ill & Healthy, Carolyn Marie Dachs Farrell

All Dissertations

This dissertation examines an individual’s perceived health status, and health values, as influences on self-initiated health action, specifically the pursuit of Direct-to-consumer (DTC) genome testing. Motivation for this independent health action may also have implications for other individual health behaviors, including the potential for positive changes that are lasting rather than temporary. Health Capability, the conceptual framework, supports individual health values and goals, ability to access valued healthcare services and includes measures of health status. However, Health Capability lacks an operationalized mapping of its major concepts. This dissertation proposes and evaluates an original concept mapping and relationships. An overview of …

Consumer Acceptance And Willingness To Pay For Genetically Modified Rice In China: A Double Bounded Dichotomous Choic Contingent Valuation Survey Calibrated By Cheap Talk, Jing Jin

Graduate Theses and Dissertations

Considering population growth, limitations on land and water resources, and contamination to the ecosystem due to agricultural activities, current rice production in China is facing pressure to fulfill national demand. Self-sufficiency of rice has been a long-held political objective of the Chinese government and it is national goal to maintain the equilibrium between the national production and consumption or even achieve a supply surplus in rice. With the developing bio-technology of genetic modification (GM), scientists believe that using genetically modified cultivars may ease the pressure mentioned above. However, both the government and the people are very cautious about large-scale cultivation …

Identification And The Significance Of Selective Proteins In Bile And Plasma Of Normal And Health-Compromised Chickens, Balamurugan Packialakshmi

Graduate Theses and Dissertations

During the last 50 years, animal breeding programs in commercial poultry have made significant progress in the bodyweight gain of broilers but led to several metabolic and skeletal disorders. Lameness associated with proximal femur known as femoral head separation (FHS) or femoral head necrosis (FHN) is one of the major metabolic disorders in poultry industry. In order to select for healthy chickens, markers that can distinguish between healthy and affected birds are required. Biomarkers from blood represent an ideal and rich source of markers which can be obtained using minimally invasive methods. The biomarkers were explored in an experimental model …

Regulation Of Phialide Morphogenesis In Aspergillus Nidulans, Hu Yin

School of Biological Sciences: Dissertations, Theses, and Student Research

Filamentous fungi have two distinctive life cycles, vegetative growth and development for sexual or asexual spore formation. The asexual reproduction in development as conidiation in Aspergillus nidulans is the dominant form of producing spores effectively. A complex conidiophore structure is developed during asexual reproduction process. The conidiophore is formed from hyphal cell and consists of stalk, vesicle, metulae, phialide and conidial spores. Phialides are essential sporogenous cells in the conidiophore structure. The growth pattern is switched from acropetal to basipetal between phialide and spores, which makes phialide a unique cell type in A. nidulans and other phialide producing fungi. …

Cointegration Analysis Of Public Expenditure On Tertiary Education And Economic Growth In Nigeria, Japheth T. Torruam, Moses A. Chiawa, Cyprian C. Abur

CBN Journal of Applied Statistics (JAS)

The paper investigates the Impact of public expenditure on tertiary education and economic growth in Nigeria using time series data for the period 1990- 2011.The econometric methodology employed was cointegration and error correction technique. The study concludes that public expenditure on tertiary education has positive impact on economic growth in Nigeria. The study recommended that government and private sectors should partner by mobilizing resources to furnish tertiary institutions and equip them with adequate facilities in order to enhance tertiary education development for sustainable economic growth.

Determinants Of Economic Growth In Nigeria, Kazeem B. Ajide

CBN Journal of Applied Statistics (JAS)

This paper investigates the role of Frazer Economic Freedom Index on FDI-growth relationship over the period spanning 1980 through 2010 using annual time series data. A Multivariate Regression approach was employed to estimate augmented growth models. Quite intriguingly, the impact of disaggregated economic freedom over aggregated composite index was found profoundly revealing. Emanated results show that the same set of variables like labour, life expectancy, degree of openness and economic freedom are factors affecting the level of economic growth in both but at different levels of significance. However, the estimates of disaggregated components of economic freedom data show that the …

Government Efforts And Personal Opinion Explain The Medicalization Of Pregnancy And Childbirth Through Time In Lower Mustang, Nepal, Ruth Baker

Independent Study Project (ISP) Collection

The way that women approach pregnancy and childbirth in rural Nepal has seen an amazing change in the past twenty to thirty years. The medicalization of this entire process, from pre-­‐ to post-­‐natal care, comes with government efforts for the increased education of women about family planning, nutrition, hygiene, and the proposed benefits of institutional versus in-­‐home delivery. In 9 villages of Lower Mustang, interviews conducted with Government Health Post workers, Female Health Volunteers, and women of different ages sought to discern personal experience and opinion about pregnancy and childbirth from the perspective of both local women and those with …

The End Of An Era: The Cancer Stem Cell Hypothesis And Its Therapeutic Implications, Emily Paton

Independent Study Project (ISP) Collection

Cancer, a leading cause of death in many developed countries, has become a global health burden. Much of the drain on healthcare systems has resulted from the high cost and ineffectiveness of conventional cancer treatments, which often lead to cancer relapse or metastasis. The failures of chemotherapy, radiation, and surgery have been elucidated by the cancer stem cell (CSC) hypothesis, which postulates that a small percentage of tumor cells drive tumorigenesis. These cells can sustain cancer through their capacity to self-renew and differentiate into specialized tumor cell types, similar to how healthy stem cells maintain healthy tissues. Conventional cancer treatments …

Premature Births And Maternal Health: An Analysis Of Risk Factors That Affect The Rate Of Prematurity / Los Nacimientos Prematuros Y La Salud Materna: Un Análisis De Los Factores De Riesgo Que Afecta La Tasa De Prematuridad, Alexandria Mickler

Independent Study Project (ISP) Collection

Research Question: What are the major socio-demographic risk factors influencing the rate of preterm birth in Valparaiso, Chile? Objectives: The objective of this study is to identify risk factors that influence the rate of preterm birth in an urban population of women living in Valparaiso, Chile. This study aims to understand whether a relationship exists between socio-demographic characteristics, such as economic level, education, lifestyle, access to medical attention and resources and the risk of prematurity. The outcomes of this study seek to determine the major biological, cultural, and social relationships and identify at-risk social groups. Additionally, this study considers the …

Educar Para Liberar Una Investigación Del Sistema De Educación En Ex. Penitenciario Y Colina 2 Y Sus Efectos / Educating For Liberty An Investigation Of The Education System In Ex. Prison And Hill 2 And Its Effects, Patrick Miller

Independent Study Project (ISP) Collection

El objetivo de esta investigación es determinar cómo funciona el sistema de educación en las cárceles de Chile y aprender los efectos de educación en los hombres encarcelados. La investigación trata de responder las siguientes preguntas: 1) ¿Qué es la motivación del estado para educar personas encarceladas? 2) ¿Qué efectos tiene educación en las cárceles? 3) ¿Cuáles son los efectos en las personas una vez que salen en libertad? Son preguntas profundas y ésta investigación solo ofrece una breve respuesta a cada uno. Esta investigación realizó entrevistas formales con un director y sub director de un liceo dentro de un …

New Study Of Altitude And Butterfly Diversity Evaluation Of Butterfly Diversity In La Hesperia And Influence Of Altitude On Diversity, Savannah Artusi

Independent Study Project (ISP) Collection

Due to the increasing effects of climate change, studies focusing on bioindicator species are becoming more necessary than ever. Additionally, knowledge about global biodiversity can be very useful to conservation organizations because it helps them determine what areas need to be conserved the most .Butterflies are useful as bioindicators due to their complex life cycles, importance in the food chain, and sensitivity to environmental changes. This project focused on studying the overall biodiversity of butterflies in the La Hesperia reserve. In addition, this study aimed to determine how butterfly diversity varies at different altitudes. To do this, the reserve was …

Protecting Human Rights During Emergencies: Delegation, Derogation, And Deference, Evan J. Criddle

Faculty Publications

Leading human rights treaties permit states as a temporary measure to suspend a variety of human rights guarantees during national crises. This chapter argues that human rights derogation is best justified as a temporary mechanism for empowering states to protect human rights, rather than as a device for enabling national authorities to advance their own interests in a manner that compromises human rights protection. Human rights treaties use broad legal standards to entrust states with responsibility for deciding what measures are best calculated to maximize human right protection during emergencies. For this delegation of authority to operate effectively, international tribunals …

Violence And Disruptive Behavior On The Difficult Trail To Utah, 1847–1868, David L. Clark

BYU Studies

One aspect of the Mormon pioneer experience has not been studied: violence. Did the pioneers have problems with fighting and other aggressive behavior? How did company leaders prevent problems and handle disputes when they inevitably arose? This article reports pioneer records mentioning arguments, punishments, and other violent actions. The stories range from a threatened whipping for children who dallied behind their group to the heartbreaking tale of handcart pioneers being whipped to keep them moving along a frozen trail. While sickness, hunger, accidents, and weather took their toll on the Mormon pioneers, violence was not a major issue. Although records …

The Children Of Lehi And The Jews Of Sepharad, Shon D. Hopkins, D. Chad Richardson

BYU Studies

The Book of Mormon strongly asserts a gathering, not only of Lehi's scattered seed but also of the "Jews." Both Lehi (quoting Joseph of Egypt) and the Old Testament prophet Ezekiel prophesied of a running together of the children of Joseph and the children of Judah. This paper proposes one way in which this prophesied unification of Joseph and Judah into "one nation" may have been in part fulfilled, namely in a joining of the Jews of Sepharad (Sephardic Jews) with the children of Lehi. This occurred when the Sephardic Jews (coming primarily from Spain and Portugal) intermarried with the …

The Mormons: An Illustrated History Of The Church Of Jesus Christ Of Latter-Day Saints, Roy A. Prete, Herman Du Toit

BYU Studies

Many predicted that the printed book would be doomed by developments in digital media. Far from it. This sumptuously illustrated "coffee table" hardcover publication by Merrell, an independent British publisher, testifies to the value of the printed book. The materiality of the medium emphasizes the synthesis of the complex visual and textual content of this publication--stressing the fact that this is a book and not a digital file after all. Stephen Hales Creative Inc., a design company in Provo, Utah, was responsible for the appealing visual design and layout of the book. The hard cover and dust jacket are both …

Educator Mindset: Perceptions Of Economic Inequality And Awareness Of Poverty On Student Potential, Cindy B. Copich

Student Work

Due to growing economic inequality and the increase of child poverty rates within the U.S., teachers today are more likely to work with students and families with increasingly complex and diverse economic needs. This study examines the significance of the relationship between educators’ awareness of poverty, perceptions of economic inequality, and mindset about talent and intelligence. The participants (N = 71) were adult students attending a Midwestern metropolitan public university’s summer educational leadership graduate course. Survey results revealed that only two of the 71 study participants had a growth mindset. Individuals with a growth mindset generally believe that through effort, …

An Exploration Of High School Engagement Factors And Their Relationship To College Completion Rates, Tamela J. Wegener

Student Work

Today our global economy is demanding a work force that is highly educated and skilled; yet many of our students entering college are not college ready despite all the assessments, increased requirements and state standards work this country has undertaken. The bridge between high school and post-secondary education needs to be built in order for this nation to move forward. This research investigates the predictors of college success. The findings indicate five critical components: (1) academic preparation; (2) demographic characteristics; (3) local and total scholarship amounts; (4) parent engagement; and (5) student engagement as measured by high school participation in …

The Art Of Motions: Understanding Illinois Civil Pretrial Motions, Steve L. Dellinger

Southern Illinois University Law Journal

This Article explores common civil pretrial motions in Illinois, primarily substantive motions under sections 2-615, 2-619, and 2-1005 of the Code of Civil Procedure.  It briefly addresses procedural motions, ethical aspects of motion practice, and how to draft and respond to a motion.  It relies on recent case law to articulate the distinctions between the substantive motions and provide the practitioner with an up-to-date understanding.  Examples are used to explain the various distinctions and what motion is appropriate in certain circumstances.  A section 2-615 motion is used to challenge the legal sufficiency of the complaint.  A section 2-619 motion is …

Shared Responsibility: Time For Illinois To Adopt The Income Shares Model Of Child Support, J. David Sanders

Southern Illinois University Law Journal

Illinois child support laws are outdated and inconsistent with the majority of child support laws in other states.  Adopted by forty states and territories, the leading child support guideline is the Income Shares Model.  The design of the Income Shares Model is to level the financial playing field for both parents by considering both parents’ incomes as well as the financial and non-financial contributions of both parents.  Unlike the Income Shares Model, Illinois’ current child support model fails to recognize the existing societal change of both parents earning an income due to the subjective focus on the non-custodial parent’s net …

A Portrait Of The New York City Lunatic Asylum On Blackwell's Island, Austin C. Labau

Undergraduate Honors Capstone Projects

Statement of Purpose

"Insanity is a subject which touches our civil rights at so many different points, that it may be said to have a place in every problem involving human responsibility." -John Ordronaux, New York State Commissioner in Lunacy, 1878.

Mental illness can reduce even the strongest person to a state of helplessness. The way in which a society treats individuals with mental illness provides a window into what that society most values - what behaviors it approves, what people it sees as most valuable, and how much society is willing to sacrifice to help those who may or …

Creation As An Ecumenical Problem: Renewed Belief Through Green Experience, Thomas Hughson

Theology Faculty Research and Publications

Loss of a sense of creaturehood and of members has occurred across the lines of divided churches in a secular context. The author explores the question whether green experience of nature can be a path toward a renewed sense of creaturehood. Bernard Lonergan’s distinction between faith and belief allows for identifying a primordial faith that interprets the cosmos as numinous. Ignatius of Loyola’s Spiritual Exercises interprets primordial faith with the biblical word of God as Creator. Why not develop local ecumenical experiments in reevangelization that address green experience?

Virginia Accomplishments Since The 2008 Climate Action Plan Release, Center For Coastal Resources Management, Virginia Institute Of Marine Science, Governor's Climate Change And Resiliency Update Commission

2014, Adaptive Planning for Flooding and Coastal Change in Virginia: Next Steps for the Commonwealth

No abstract provided.

Epistemological Realism And Onto-Relations, Max Lewis Edward Andrews

Liberty Theological Review

The traditional concept of knowledge is a justified true belief. The bulk of contemporary epistemology has focused primarily on that task of justification. Truth seems to be a quite obvious criterion—does the belief in question correspond to reality? My contention is that the aspect of ontology is far too separated from epistemology. This onto-relationship of between reality and beliefs require the epistemic method of epistemological realism. This is not to diminish the task of justification. I will then discuss the role of inference from the onto-relationships of free invention and discovery and whether it is best suited for a foundationalist …

December 2014 Commencement Program, Bowling Green State University

Commencement Programs

No abstract provided.

A Study Protocol: Using Demand-Side Financing To Meet The Birth Spacing Needs Of The Underserved In Punjab Province In Pakistan, Syed Khurram Azmat, Moazzam Ali, Waqas Hameed, Ghulam Mustafa, Ghazanfer Abbas, Muhammad Ishaque, Mohsina Bilgrami, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: High fertility rates, unwanted pregnancies, low modern contraceptive prevalence and a huge unmet need for contraception adversely affect women’s health in Pakistan and this problem is compounded by limited access to reliable information and quality services regarding birth spacing especially in rural and underserved areas. This paper presents a study protocol that describes an evaluation of a demand-side financing (DSF) voucher approach which aims to increase the uptake of modern contraception among women of the lowest two wealth quintiles in Punjab Province, Pakistan.

Methods/Design: This study will use quasi-experimental design with control arm and be implemented in: six government …

Sexual Violence And Sub-Saharan Migrants In Morocco: A Community-Based Participatory Assessment Using Respondent Driven Sampling, Ines Keygnaert, Abdessamad Dialmy, Altay Manço, Jeroen Keygnaert, Nicole Vettenburg, Kristien Roelens, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: The European Union contracted Morocco to regulate migration from so-called “transit migrants” from Morocco to Europe via the European Neighbourhood Policy. Yet, international organisations signal that human, asylum and refugee rights are not upheld in Morocco and that many sub-Saharan migrants suffer from ill-health and violence. Hence, our study aimed at 1) investigating the nature of violence that sub-Saharan migrants experience around and in Morocco, 2) assessing which determinants they perceive as decisive and 3) formulating prevention recommendations.

Methods: Applying Community-Based Participatory Research, we trained twelve sub-Saharan migrants as Community Researchers to conduct in-depth interviews with peers, using Respondent …

Maternal And Perinatal Health Research Priorities Beyond 2015: An International Survey And Prioritization Exercise, Joao Paulo Souza, Mariana Widmer, Ahmet Metin Gülmezoglu, Theresa Anne Lawrie, Ebunoluwa Aderonke Adejuyigbe, Guillermo Carroli, Caroline Crowther, Sheena M. Currie, Therese Dowswell, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: Maternal mortality has declined by nearly half since 1990, but over a quarter million women still die every year of causes related to pregnancy and childbirth. Maternal-health related targets are falling short of the2015 Millennium Development Goals and a post-2015 Development Agenda is emerging. In connection with this, setting global research priorities for the next decade is now required.

Methods: We adapted the methods of the Child Health and Nutrition Research Initiative (CHNRI) to identify and set global research priorities for maternal and perinatal health for the period 2015 to 2025. Priority research questions were received from various international …

Newborn Care In Indonesia, Lao People’S Democratic Republic And The Philippines: A Comprehensive Needs Assessment, Els Duysburgh, Birgit Kerstens, Melissa Diaz, Vini Fardhdiani, Katherine Ann Reyes, Khamphong Phommachanh, Marleen Temmerman, Basil Rodriques, Nabila Zaka

Obstetrics and Gynaecology, East Africa

Background: Between 1990 and 2011, global neonatal mortality decline was slower than that of under-five mortality. As a result, the proportion of under-five deaths due to neonatal mortality increased. This increase is primarily a consequence of decreasing post-neonatal and child under-five mortality as a result of the typical focus of child survival programmes of the past two decades on diseases affecting children over four weeks of age. Newborns are lagging behind in improved child health outcomes. The aim of this study was to conduct a comprehensive, equity-focussed newborn care assessment and to explore options to improve newborn survival in Indonesia, …

Implementation Of Evidence-Based Antenatal Care In Mozambique: A Cluster Randomized Controlled Trial: Study Protocol, Leonardo Chavane, Mario Merialdi, Ana Pilar Betrán, Jennifer Requejo-Harris, Eduardo Bergel, Alicia Aleman, Mercedes Colomar, Maria Luisa Cafferata, Alicia Carbonell, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Background: Antenatal care (ANC) reduces maternal and perinatal morbidity and mortality directly through the detection and treatment of pregnancy-related illnesses, and indirectly through the detection of women at increased risk of delivery complications. The potential benefits of quality antenatal care services are most significant in low-resource countries where morbidity and mortality levels among women of reproductive age and neonates are higher. WHO developed an ANC model that recommended the delivery of services scientifically proven to improve maternal, perinatal and neonatal outcomes. The aim of this study is to determine the effect of an intervention designed to increase the use of …