Digital Commons Network^™

How To Use Anti-Mullerian Hormone Testing To Diagnose Granulosa Cell Tumors In Mares, Dirk K. Vanderwall, Kerry A. Rood

All Current Publications

This fact sheet describes how to use Anti-Mullerian hormone testing to diagnose granulosa cell tumors in mares.

A Brain Computer Interface For Interactive And Intelligent Image Search And Retrieval, Shitij P. Kumar

Theses

This research proposes a Brain Computer Interface as an interactive and intelligent Image Search and Retrieval tool that allows users, disabled or otherwise to browse and search for images using brain signals. The proposed BCI system implements decoding the brain state by using a non-invasive electroencephalography (EEG) signals, in combination with machine learning, artificial intelligence and automatic content and similarity analysis of images. The user can spell search queries using a mental typewriter (Hex-O-Speller), and the resulting images from the web search are shown to the user as a Rapid Serial Visual Presentations (RSVP). For each image shown, the EEG …

A Biblical Foundation Counseling Strategy To Direct Couples To Become One Flesh In Marriage, Colin Seager

Doctoral Dissertations and Projects

This project will outline steps in counseling newly married couples to develop biblical, physical, emotional, social, and spiritual unity within marriage. A review of currently available marital and pre-marital counseling suggests the focus centers on intimacy, communication issues, and being happy together versus truly becoming one flesh. This ministry tool will enable pastors to counsel and prepare couples effectively for marriage with the richness God designed for marriage and to fortify them against marital temptation and marital fatigue. Based on a review of available resources and data collected from a control group comprised of sixty individuals, an implementable discipleship program …

A Method To Develop Neck Injury Criteria To Aid Design And Test Of Escape Systems Incorporating Helmet Mounted Displays, Jeffrey C. Parr

Theses and Dissertations

HMDs are becoming common human-machine interface equipment in manned military flight, but introducing this equipment into the overall aircraft escape system poses new and significant system design, development, and test concerns. Although HMDs add capabilities, which improve operator performance, the increased capability is often accompanied by increased head supported mass. The increased mass can amplify the risk of pilot neck injury during ejection when compared to lighter legacy helmets. Currently no adequate USAF neck injury criteria exist to effectively guide the requirements, design, and test of escape systems for pilots with HMDs. This research effort presents a novel method to …

Using Non-Environmental Law To Accomplish Environmental Objectives, Todd S. Aagaard

Faculty Publications

The current prolonged period of congressional impasse on environmental issues, in which symbolic ideological skirmishes have largely supplanted constructive engagement, makes clear that Congress is unlikely to generate progress on environmental issues any time soon. In response to this legislative stalemate, some environmental law scholars have advocated for giving the Environmental Protection Agency enhanced capability to take administrative action under the authority of existing environmental statutes.

Without disagreeing with those arguments, this article contends that we also need strategies for environmental law that transcend, not just adapt, the canonical environmental statutes that have been the field’s mainstay since the early …

Stress-Induced Cocaine Seeking Requires A Beta-2 Adrenergic Receptor-Regulated Pathway From The Ventral Bed Nucleus Of The Stria Terminalis That Regulates Crf Actions In The Ventral Tegmental Area, Oliver Vranjkovic, Paul J. Gasser, Clayton H. Gerndt, David A. Baker, John R. Mantsch

Biomedical Sciences Faculty Research and Publications

The ventral bed nucleus of the stria terminalis (vBNST) has been implicated in stress-induced cocaine use. Here we demonstrate that, in the vBNST, corticotropin releasing factor (CRF) is expressed in neurons that innervate the ventral tegmental area (VTA), a site where the CRF receptor antagonist antalarmin prevents the reinstatement of cocaine seeking by a stressor, intermittent footshock, following intravenous self-administration in rats. The vBNST receives dense noradrenergic innervation and expresses β adrenergic receptors (ARs). Footshock-induced reinstatement was prevented by bilateral intra-vBNST injection of the β-2 AR antagonist, ICI-118,551, but not the β-1 AR antagonist, betaxolol. Moreover, bilateral intra-vBNST injection of …

Cyclic Ovarian Hormone Modulation Of Supraspinal Δ9-Tetrahydrocannabinol-Induced Antinociception And Cannabinoid Receptor Binding In The Female Rat, Alexa A. Wakley, Alisha A. Mcbride, Linda K. Vaughn, Rebecca M. Craft

Biomedical Sciences Faculty Research and Publications

Estrous cycle-related fluctuations in delta-9-tetrahydrocannabinol (THC)-induced antinociception have been observed in the rat. The aim of this study was to determine which major ovarian hormone modulates the antinociceptive effects of i.c.v. THC, and whether hormone modulation of THC's behavioral effects could be due to changes in brain cannabinoid receptors (CBr). Vehicle (oil) or hormones (estradiol or progesterone, or both) were administered to female rats on days 3 and 7 post-ovariectomy. On the morning or afternoon of day 8 or day 9, vehicle or THC (100 μg) was administered i.c.v. Paw pressure, tail withdrawal, locomotor activity and catalepsy tests were conducted …

Portland State Magazine, Portland State University. Office Of University Communications

Portland State Magazine

PSU’s alumni magazine, published 2-3 times a year. In this issue: Library archivist finds old recordings of big name speakers; PSU’s new fundraising structure creates financial sustainability; sharing space with OSHU and OSU in a new building on Portland’s South Waterfront; Ann Marie Fallon shares Honors College admission essays; alumna Amelia Pape brings groceries into neighborhoods; and more

The Role Of Tight And Adherens Junctions In Cervical Neoplasia, Ciaran Cunniffe

Doctoral

Cervical cancer is the second most common cancer in women and is caused by a persistent infection of the cervical epithelium by the Human Papilloma Virus (HPV). Adherens (AJ) and tight junctions (TJ) play a key role in maintaining the apical-basolateral polarity and cohesive structure of epithelial cells. These junctions are maintained by the interaction of several key proteins including, claudins, catenins, cadherins and SNAIL. This study aims to identify the expression profile of several AJ and TJ proteins and to identify and genotype HPV DNA in several cases of cervical neoplasia. This study also aims to investigate the pathogenesis …

Niche Differentiation In Meta Bourneti And M. Menardi (Araneae, Tetragnathidae) With Notes On The Life History, Stefano Mammola, Marco Isaia

International Journal of Speleology

Meta menardi and M. bourneti are two species of spiders inhabiting caves and other subterranean habitats. The occurrence of both species within the same cave has never been proved convincingly and several authors hypothesized a complete niche differentiation mainly based on microclimatic conditions.In order to study the apparent niche differentiation of the two species, we studied several populations of M. menardi and M. bourneti occurring in six caves in the Western Italian Alps (NW Italy). A series of squared plots were monitored monthly from March 2012 to February 2013. At each survey, we counted individuals and we collected the main …

Full Issue 43(3)

International Journal of Speleology

No abstract provided.

The Experience Of Reducing Environmental Risks In An Environmental Justice Community, Gabriela Dory

Dissertations

Research on Environmental Justice (EJ) communities has focused on quantitative assessment of environmental hazards and general physical health problems. Little is known about how individuals living in EJ communities perceive their environmental risks and how they reduce environmental risks. The purpose of the study is to explore and describe the perceived environmental risks and the experience of reducing environmental risk among individuals living in an EJ community.

A qualitative and longitudinal design with a descriptive phenomenological method is used to recruit 23 participants living in a known EJ community in the urban area of New Jersey. A total of 43 …

Medical School Watercooler Newsletter - August 31, 2014, Lindsey Lyle

Watercooler Newsletter

This is the August 31, 2014 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Center for Lung Biology Hosts Lung Bowl
• Students: Mark Your Calendar for Jag Health and Wellness Day
• USA Welcomes Dr. Brett Baskovich
• TEDMED to be Streamed Live at USA Biomedical Library
• Basic Medical Sciences Graduate Program Student Receives Edwin R. Hughes Award
• Benefit of USA Children's Clinic Reading Program Validated Through New AAP Policy

Investigating Propargyl-Linked Antifolates In Inhibiting Bacterial And Fungal Dihydrofolate Reductase, Joshua Andrade

Honors Scholar Theses

Antimicrobial agents have been invaluable in reducing illness and death associated with bacterial infection. However, over time, bacteria have evolved resistance to all major drug classes as a result of selective pressure. The advancement of new drug compounds is therefore vital. The Anderson-Wright Lab has focused on developing potent and selective inhibitors of dihydrofolate reductase (DHFR), an enzyme key in cell proliferation and survival, in several pathogenic species. The lab has found that a set of compounds, known as propargyl-linked antifolates, are DHFR inhibitors that are both biologically effective and have strong pharmacokinetic properties.

The efficacy of novel propargyl-linked antifolates …

Translation And Transcription Are Required For Endogenous Bursting After Long Term Removal Of Neuromodulators, Stefanie Eisenbach

Theses

Motor pattern-generating networks depend on neuromodulatory inputs to regulate the network activity. The pyloric network of the Cancer borealis stomatogastric ganglion (STG), a rhythmic motor pattern-generating network, requires modulatory inputs to generate this activity. When neuromodulatory inputs are removed, the pyloric network falls silent. However, patterned pyloric activity recovers spontaneously in about 24 hours in organ culture. To determine if synthesis of new proteins are involved in the recovery of pyloric activity after prolonged elimination of neuromodulators, translation inhibitors are tested on the recovery process of pyloric activity in C. borealis. In vitro experiments are conducted; the STG is …

Formation Of Branching Angles At Bifurcations Of Ant Trail Networks, Subash Kusum Ray

Theses

Ants form dendritic trail networks around the nest to search for and exploit food sources located at the periphery of the network. Studies found these trail networks to be very efficient for the ants in terms of time and energy, which later was found stored in the bifurcation angle (θ) of the branches of these trail networks. It has been observed, that bifurcations are symmetrical when moving from the nest to the food source, while are asymmetrical when moving back towards the nest. The mean bifurcation angles have been found to be 50° - 80° for networks radiating out from …

Preparation And Characterization Of Fast Dissolving Pullulan Films Containing Griseofulvin Nanoparticles For Bioavailability Enhancement, Zhelun Ma

Theses

The aim of this study is to enhance the bioavailability of griseofulvin, a model poorly water-soluble drug, via increasing drug dissolution rate through preparation of drug nanoparticle-laden, pullulan-based strip films. The work entails (i) wet-milling griseofulvin in a stirred media mill using pullulan (polymer) along with sodium dodecyl sulfate (surfactant) as stabilizers, (i i) preparing strip films by casting-drying a precursor suspension consisting of the mixture of the milled drug suspension and a film-forming pul l ul an–xanthan gum-glycerin solution, (iii) characterizing the suspensions and the films, and (iv) exploring the effects of film thickness, drug and xanthan gum loadings, …

The Relationship Between Traumagenic Dynamic Responses Towards Childhood Sexual Abuse, Ethnic Identity, Social Support, Trauma Severity, And Attitudes Towards Interpersonal Relationships In Adolescent Females, Nita J. Makhija

Seton Hall University Dissertations and Theses (ETDs)

This study used the theory of traumagenic dynamics (TD) to examine how symptomatology resulting childhood sexual abuse (CSA) are related to the attitudes adolescent females have towards interpersonal relationships. The ultimate goal being that this understanding can inform the creation and implementation of empirically based clinical interventions that specifically target CSA-related symptoms which are associated with the endorsement of unhealthy attitudes towards romantic relationships. In examining this relationship, family support and ethnic identity were examined as protective factors against the endorsement of unhealthy attitudes towards romantic relationships, and trauma severity and the presence of domestic violence in the home were …

“So Succeeded By A Kind Providence”: Communities Of Color In Eighteenth Century Boston, Eric M. Hanson Plass

Graduate Masters Theses

The Freedom Trail has become an iconic symbol and major tourist attraction in the City of Boston. Yet since its Cold War-era inception, the Freedom Trail has remained problematically focused on a consensus history of leading white men who brought forth the American Revolution. Other heritage trails - most notably the Black Heritage Trail - have been established to correct the deficiencies of the Freedom Trail. These organizations have attempted to provide a revisionist counter-point by telling stories of internal struggle and by exploring groups traditionally overlooked by historians. However, with so many trails possessing so many particularized foci, many …

Transcriptional Regulation Of Sinorhizobium Meliloti Cell Cycle-Related Genes In The Δcbra Mutant And Root Nodules Of Medicago Sativa, Corey S. Hazekamp

Graduate Masters Theses

Sinorhizobium meliloti is a Gram-negative alphaproteobacterium and nitrogen-fixing symbiont, which undergoes a novel cell cycle modification during its' host-microbe interaction. I intend to monitor the transcriptional regulation of cell cycle-related genes during free-loving growth, in addition to monitoring their expression during symbiosis. Using genes known to be regulated by CtrA in C. crescentus or predicted to be regulated by CtrA in S. meliloti, I aim to show how certain cell cycle genes are regulated in S. meliloti. In C. crescentus, CtrA acts as a transcription factor that is active when phosphorylated and inactive when not phosphorylated. In …

From Horse To Electric Power At The Metropolitan Railroad Company Site: Archaeology And The Narrative Of Technological Change, Miles Shugar

Graduate Masters Theses

The Metropolitan Railroad Company Site in Roxbury (Boston), Massachusetts, was first excavated in the late 1970s by staff of the Museum of Afro American History. Researchers recovered nearly 20,000 artifacts related to the site's life as a horsecar street railway station and carriage manufacturer from 1860 to 1891, its subsequent conversion into an electric street railway until around 1920, and finally its modern use as an automobile garage. Using the framework of behavioral archaeology, this project uses GIS-based spatial methods and newly collected documentary evidence to reexamine the site's assemblage of horse accoutrements and carriage manufacturing byproducts. Artifact distribution maps …

Aboriginal Maple Syrup Values Report, Annette Chrétien

Contemporary Studies

This report examines the values associated with maple syrup practices in Aboriginal contexts. It is based on fifteen interviews conducted with Aboriginal people who have knowledge of maple syrup practices in Ontario. The interviewees included both First Nations and Metis people.

Fructose-2,6-Bisphosphate Synthesis By 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase 4 (Pfkfb4) Is Required For The Glycolytic Response To Hypoxia And Tumor Growth, Jason Chesney, Jennifer Clark, Alden C. Klarer, Yoannis Imbert-Fernandez, Andrew N. Lane, Sucheta Telang

Markey Cancer Center Faculty Publications

Fructose-2,6-bisphosphate (F2,6BP) is a shunt product of glycolysis that allosterically activates 6-phosphofructo-1-kinase (PFK-1) resulting in increased glucose uptake and glycolytic flux to lactate. The F2,6BP concentration is dictated by four bifunctional 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) with distinct kinase:phosphatase activities. PFKFB4 is over-expressed in human cancers, induced by hypoxia and required for survival and growth of several cancer cell lines. Although PFKFB4 appears to be a rational target for anti-neoplastic drug development, it is not clear whether its kinase or phosphatase activity is required for cancer cell survival. In this study, we demonstrate that recombinant human PFKFB4 kinase activity is 4.3-fold greater than …

Religious Beliefs About Suffering: Measure Validation And Relationships With Well-Being, Amy Hale

Doctoral Dissertations

Beliefs are central to all world religions, but there is limited data on the relationships between specific religious beliefs and well-being. This dissertation presents findings from two studies of beliefs about suffering using the Views of Suffering Scale (VOSS; Hale-Smith, Park, & Edmondson, 2012).

Study 1 was a cross-sectional validation study using an online sample of 1000 participants self-identified as Catholic, Protestant, Atheist/Agnostic, Hindu, Muslim, or Jewish. Measures included information regarding demographics and measures of religious history and beliefs. Results of Study 1 indicated differences in beliefs based on age, geographic region, religious affiliation, and how religious or spiritual participants …

Comparative Molecular Docking Studies With Abcc1 And Aquaporin 9 In The Arsenite Complex Efflux, Shiv Poojan, Anupam Dhasmana, Qazi Mohammad Sajid Jamal, Mohd Haneef, Mohtashim Lohani

School of Medicine Publications

Arsenic is the most toxic metalloid present in the natural environment in both organic and inorganic arsenic forms. Inorganic arsenic is often more hazardous than the organic form. Arsenite and arsenate compounds are the major inorganic forms which are toxic causing severe human health dysfunction including cancer. Excretion of arsenic from the system is found elusive. Therefore, it is of interest to screen channel proteins with the arsenic complex in the different combination of arsenic, GSH (glutathione) and arsenic, selenium using docking methods. The mode of arsenic removal. The complex structure revealed the mode of arsenic binding efficiency with the …

Reveal, Rudith Senam Abla Akorli

Theses

The thesis work named Reveal is a sculptural jewelry series that has a subtle tone of contemporary fashion. Reveal was created by studying traditional African art techniques for adorning the head and hair. The work analyzes the symbolic meaning of various hair styles and headgears within African cultures, by specifically zooming in on different threading hairstyles and free flowing sculptural headgears.

This thesis highlights the importance and evolution of color within African cultures and how color symbolically reflects status and behavior of individuals within Africa. Reveal exposes the time intensive practices characteristic of Ghanaian daily life and juxtaposes them to …

Joint Turbary: Heaney’S “Digging” And Eoghan Rua Ó Súilleabháin’S “A Shéamais, Déan Dom”, Cóilín Owens

Irish Studies South (Archived)

No abstract provided.

The Murray Ledger And Times, August 29, 2014, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

The Bison, August 29, 2014

The Bison Newspapers

No abstract provided.

The Virtues Of Law In The Politics Of Religious Freedom, Benjamin Berger

Articles & Book Chapters

The moral force and capacity for inspiration of both religion and politics alike arise in part from the sense that they authentically map the world as we nd it, yielding claims about how it should be. This paper asks what role we might imagine for law in this “hyperreal” world of religion and politics, arguing that law can display distinctive virtues linked to its capacity for strategic agnosticism about the real. Applying Sunstein’s idea of “incompletely theorized agreements” to the politics of religious freedom, the paper examines the role of law as a tool of adhesion in two very different …