Digital Commons Network^™

Simple Objective Detection Of Human Lyme Disease Infection Using Immuno-Pcr And A Single Recombinant Hybrid Antigen, Micah D. Halpern, Claudia R. Molins, Martin Schriefer, Mollie W. Jewett

Faculty Bibliography 2010s

A serology-based tiered approach has, to date, provided the most effective means of laboratory confirmation of clinically suspected cases of Lyme disease, but it lacks sensitivity in the early stages of disease and is often dependent on subjectively scored immunoblots. We recently demonstrated the use of immuno-PCR (iPCR) for detecting Borrelia burgdorferi antibodies in patient serum samples that were positive for Lyme disease. To better understand the performance of the Lyme disease iPCR assay, the repeatability and variability of the background of the assay across samples from a healthy population (n = 36) were analyzed. Both of these parameters were …

No Evidence Of Metabolic Depression In Western Alaskan Juvenile Steller Sea Lions (Eumetopias Jubatus), Lisa A. Hoopes, Lorrie D. Rea, Aaron Christ, Graham A. J. Worthy

Faculty Bibliography 2010s

Steller sea lion (Eumetopias jubatus) populations have undergone precipitous declines through their western Alaskan range over the last four decades with the leading hypothesis to explain this decline centering around changing prey quality, quantity, or availability for this species (i.e., nutritional stress hypothesis). Under chronic conditions of reduced food intake sea lions would conserve energy by limiting energy expenditures through lowering of metabolic rate known as metabolic depression. To examine the potential for nutritional stress, resting metabolic rate (RMR) and body composition were measured in free-ranging juvenile Steller sea lions (N = 91) at three distinct geographical locations (Southeast Alaska, …

Mediators Of Monocyte Migration In Response To Recovery Modalities Following Resistance Exercise, Adam R. Jajtner, Maren S. Fragala, Jeremy R. Townsend, Adam M. Gonzalez, Adam J. Wells, David H. Fukuda, Jeffrey R. Stout, Jay R. Hoffman

Faculty Bibliography 2010s

Mediators of monocyte migration, complement receptor-3 (CR3), and chemokine ligand-4 (CCL4) were measured in response to recovery modalities following resistance exercise. Thirty resistance-trained men (23.1 +/- 2.9 y; 175.2 +/- 7.1 cm; 82.1 +/- 8.4 kg) were given neuromuscular electric stimulation (NMES), cold water immersion (CWI), or control (CON) treatments immediately following resistance exercise. Blood samples were obtained preexercise (PRE), immediately (IP), 30 minutes (30 P), 24 hours (24 H), and 48 hours (48 H) after exercise for measurement of circulating CCL4 and CR3 expression on CD14+ monocytes, by assay and flow cytometry. Circulating CCL4 showed no consistent changes. Inferential …

Lakes And Rivers As Microcosms, Version 2.0, David G. Jenkins

Faculty Bibliography 2010s

Limnology has been greatly influenced by The lake as a Microcosm (Forbes, 1887), which described a holistic focus on the internal machinations of singular, island-like aquatic ecosystems. I consider three persistent influences of The lake as a Microcosm: as an organizing paradigm for the teaching of limnology relative to its practice; the idea that inland waters are like islands, and the replicability of types of inland waters. Based on inspection of recent peer-reviewed literature and 32 limnology texts, we teach limnology according to Forbes but do not practice it in that holistic context. Instead, we practice limnology as aquatic ecology. …

Environment-Responsive Nanophores For Therapy And Treatment Monitoring Via Molecular Mri Quenching, Charalambos Kaittanis, Travis M. Shaffer, Anuja Ogirala, Santimukul Santra, J. Manuel Perez, Gabriela Chiosis, Yueming Li, Lee Josephson, Jan Grimm

Faculty Bibliography 2010s

The effective delivery of therapeutics to disease sites significantly contributes to drug efficacy, toxicity and clearance. Here we demonstrate that clinically approved iron oxide nanoparticles (Ferumoxytol) can be utilized to carry one or multiple drugs. These so called 'nanophores' retain their cargo within their polymeric coating through weak electrostatic interactions and release it in slightly acidic conditions (pH 6.8 and below). The loading of drugs increases the nanophores' transverse T2 and longitudinal T1 nuclear magnetic resonance (NMR) proton relaxation times, which is proportional to amount of carried cargo. Chemotherapy with translational nanophores is more effective than the free drug in …

Examining Emotional Responses To Effective Versus Ineffective Virtual Buddies, Kathleen Ingraham

Electronic Theses and Dissertations

The purpose of this research study was to explore the impact of virtual character design on user emotional experience and user behavior in a simulated environment. With simulation training increasing in popularity as a tool for teaching social skills, it is essential that social interactions in virtual environments provide authentic opportunities for practice (Swartout et al., 2006). This study used Interactive Performance Theory (Wirth, 2012) to examine the effect of designing a virtual buddy character with ineffective traits instead of effective or expert traits. The sample population for this study (n = 145) consisted of first year university students enrolled …

Bioarchaeological Assessment Of Diet And Changes In Femoral And Humeral Stable Isotopic Values Among Subadults At Medieval Alytus, Lithuania., Katherine Page

Electronic Theses and Dissertations

Establishing a chronology of variation in isotopic values can reveal frailty associated with biological and social age, as well as highlight individuals who vary from typical patterns. Although general dietary characteristics and infant feeding practices were previously unknown for subadults excavated from the cemetery at Alytus, Lithuania (14th-18th centuries), previous research concludes that Alytus' subadults experienced high rates of physiological, metabolic, non-specific stress, in addition to specific diseases like tuberculosis. To investigate nuanced relationships between diet and mortality, nitrogen and carbon stable isotopes from the femoral and humeral midshaft diaphyses of 70 subadults (32 weeks gestation to16 years) were analyzed. …

Host And Bacterial Determinants Of Staphylococcus Aureus Nasal Colonization In Humans, Gowrishankar Muthukrishnan

Electronic Theses and Dissertations

Staphylococcus aureus (SA), an opportunistic pathogen colonizing the anterior nares in approximately 30% of the human population, causes severe hospital-associated and community-acquired infections. SA nasal carriage plays a critical role in the pathogenesis of staphylococcal infections and SA eradication from the nares has proven to be effective in reducing endogenous infections. To understand SA nasal colonization and its relation with consequent disease, assessment of nasal carriage dynamics among a diverse population and determining factors responsible for SA nasal carriage have become major imperatives. Here, we report on an extensive longitudinal monitoring of SA nasal carriage in 109 healthy individuals over …

Effects Of Weaning Age On Body Composition And Growth Of Ex Situ California Sea Lion (Zalophus Californianus) Pups, Brandon Davis

Electronic Theses and Dissertations

Pinnipeds exhibit a wide range of lactation strategies that vary from just a few days to nearly three years in duration. Phocids have a relatively short, intense nursing period culminating with weaning after just a few days or weeks, while dependent otariids generally take several months of consuming a combined milk and solid food diet before being completely independent. The transition to nutritional independence can be particularly challenging for newly weaned pups, which must adjust to behavioral, physiological and nutritional changes as a milk diet is replaced with solid food. An interruption in energy resources during this formative stage could …

The Design And Evaluation Of A Video Game To Help Train Perspective-Taking And Empathy In Children With Autism Spectrum Disorder, Darin Hughes

Electronic Theses and Dissertations

This paper discusses the design, implementation, and evaluation of a serious game intended to reinforce applied behavior analysis (ABA) techniques used with children with autism spectrum disorder (ASD) by providing a low cost and easily accessible supplement to traditional methods. Past and recent research strongly supports the use of computer assisted instruction in the education of individuals with ASD (Moore & Calvert, 2000; Noor, Shahbodin, & Pee, 2012). Computer games have been shown to boost confidence and provide calming mechanisms (Griffiths, 2003) while being a safe environment for social exploration and learning (Moore, Cheng, McGrath, & Powell, 2005). Games increase …

Creating And Examining An Online Advising Module For Graduate Students: A Usability Study, Leah Mitchell

Electronic Theses and Dissertations

Advisors are always examining best practices when serving students with technology. Online instruction has become a popular choice for students in higher education, and educators and other student personnel are looking to further accommodate their students by including academic services as part of a virtual environment. This study examines the usefulness of an online advising module geared at graduate students. I conducted a usability study of an online advising module created for graduate students in the College of Education and Human Performance (CEDHP) at the University of Central Florida. The online advising module was presented to current graduate students in …

Twitter Implementation Within Megachurches: An Examination Of The Social Media's Effectiveness, Andrea Thompson

Electronic Theses and Dissertations

This study identified what Twitter followers were discussing in reference to the top five megachurches in size. The methods utilized within this study involved an examination of all tweets hashtagging the top five megachurches over a sixteen day timeframe. The first research question was answered by categorizing tweets into predetermined content categories. This study also addressed the second research question by determining if Twitter implementation was beneficial in executing the missions of the top five megachurches. This question was answered by analyzing tweets using a five point Likert scale measuring how reflective each tweet was to the mission statement of …

Student Engagement And Ethical Care In A Title I Middle School Program, Marguerite Anderson

Electronic Theses and Dissertations

The purpose of this dissertation was to determine if the foundational constructs (student engagement and ethical care) were experienced by the 8th grade students that participated in a morning tutoring program: Future Problem Solvers. A mixed methods design was adopted for the purpose of this study including raw data, survey data, informal observations, and face-to-face interviews. The goal was to determine if the 28 participants (male and female) demonstrated academic success on the Florida Comprehensive Achievement Test (Science). The study was also conducted in order to explore the level of student engagement and the development of reciprocating relationships based ethical …

Biomarkers Of Muscle Quality: N-Terminal Propeptide Of Type Iii Procollagen And C-Terminal Agrin Fragment Responses To Resistance Exercise Training In Older Adults, Maren S. Fragala, Adam R. Jajtner, Kyle S. Beyer, Jeremy R. Townsend, Nadia S. Emerson, Tyler C. Scanlon, Leonardo P. Oliveira, Jay R. Hoffman, Jeffrey R. Stout

Faculty Bibliography 2010s

Background N-terminal peptide of procollagen type III (P3NP) and C-terminal agrin fragment (CAF) are circulating biomarkers that are related to lean body mass in older adults. P3NP is a circulating marker reflective of muscular structural remodeling while CAF is a circulating marker of neuromuscular remodeling. As resistance exercise is an established intervention that can effectively improve muscle quality, we sought to evaluate circulating biomarker changes corresponding to a resistance exercise intervention in older adults. Methods Twenty-three older adults (aged 61 to 85 years) were randomized into an intervention (6-week resistance training) or control group. Resting circulating P3NP, CAF, lean body …

Proteasome Inhibition Augments Cigarette Smoke-Induced Gm-Csf Expression In Trophoblast Cells Via The Epidermal Growth Factor Receptor, Ya-Yuan Fu, Jennifer C. Nergard, Nicole K. Barnette, Yan-Ling Wang, Karl X. Chai, Li-Mei Chen

Faculty Bibliography 2010s

Maternal cigarette smoking has adverse effects on pregnancy outcomes. The granulocyte-macrophage colony-stimulating factor (GM-CSF) is an essential cytokine for a normal pregnancy. We investigated the impact of cigarette smoke extract (CSE) on GM-CSF expression in human cytotrophoblast cells and suggested a cellular mechanism underlying the CSE-induced GM-CSF expression. An immortalized normal human trophoblast cell line (B6Tert-1) was treated with CSE. The viability and proliferation of the CSE-treated B6Tert-1 cells were evaluated, and the expression of GM-CSF in these cells was quantified at the mRNA and the protein levels by means of reverse-transcription and quantitative polymerase chain reaction (RT-qPCR); and enzyme-linked …

Comparison Of Traditional Educative Delivery To Online Education In United States History As Measured By Florida's End-Of-Course Examinations In A Large Urban School District In Central Florida, William Wilson

Electronic Theses and Dissertations

Student participation in online courses has been growing steadily for the past decade, and the trend appears to continue the growth in this form of instructional delivery method for the foreseeable future (iNACOL, 2012). To date, little research exploring student success rates exists in the social studies. This particular study was conducted to examine what differences, if any, existed in the End-Of-Course (EOC) scores of 11th grade United States history students who took the course in a traditional, face-to-face format versus students who took the same course online through Florida Virtual School. For this study, proper permission was received from …

Human Detection, Tracking And Segmentation In Surveillance Video, Guang Shu

Electronic Theses and Dissertations

This dissertation addresses the problem of human detection and tracking in surveillance videos. Even though this is a well-explored topic, many challenges remain when confronted with data from real world situations. These challenges include appearance variation, illumination changes, camera motion, cluttered scenes and occlusion. In this dissertation several novel methods for improving on the current state of human detection and tracking based on learning scene-specific information in video feeds are proposed. Firstly, we propose a novel method for human detection which employs unsupervised learning and superpixel segmentation. The performance of generic human detectors is usually degraded in unconstrained video environments …

Examining The Effects Of Interactive Dynamic Multimedia And Direct Touch Input On Performance Of A Procedural Motor Task, Matthew Marraffino

Electronic Theses and Dissertations

Ownership of mobile devices, such as tablets and smartphones, has quickly risen in the last decade. Unsurprisingly, they are now being integrated into the training and classroom setting. Specifically, the U.S. Army has mapped out a plan in the Army Learning Model of 2015 to utilize mobile devices for training purposes. However, before these tools can be used effectively, it is important to identify how the tablets' unique properties can be leveraged. For this dissertation, the touch interface and the interactivity that tablets afford were investigated using a procedural-motor task. The procedural motor task was the disassembly procedures of a …

Calamity Of The White Picket, Garnelo Harstien

Electronic Theses and Dissertations

Calamity of the White Picket is a collection of essays that portray how perfection-whether a perfect image, perfect relationship, perfect friendship, or perfect family-becomes withered down, destroyed, and turned into something else. They explore how the idealized image of a family surrounded by a cute white picket fence is dismantled and rearranged through theft, addiction, and a disintegrated family. The essays explore drug addictions, childhood nostalgia, the relationship between heritage and property, innocence, and a stolen best friend. The collection is a train ride of family problems, broken friendships, lying and stealing, and hidden secrets about love and sex. Through …

Performing On The Screen: An Exploration Of Gender Representation In Technology Video Advertisements, Subriena Persaud

Electronic Theses and Dissertations

This study investigates the representation of gender in technology-related video advertisements. This thesis quantitatively and qualitatively examined 54 of the most recent commercials by the top nine Fortune 500 technology companies. A total of 407 characters were coded and quantitatively analyzed while the videos themselves were qualitatively assessed with particular attention given to the videos' themes and the interactions between the characters and the technology products and services. Results of the analyses showed that there were more male, Caucasian characters than any other character type based on gender and race/ethnicity. Females were mainly characterized according to traditional stereotypes, such as …

Patents As Business Intelligence Tools, Amy Jansen

Librarian Publications

As most entrepreneurs and business owners can tell you, one of the most significant considerations that companies face is how to protect their work. Managing intellectual property is now integrated with overall business models and corporate strategy. For this reason, patents have become crucial strategic pieces in business and competitive intelligence in the twenty-first century. Having the right patents, and even more importantly, knowing how to use them can either bolster or harm a company. As technology and rapid advancements in innovation become the cornerstone of corporate success, companies’ research and development (R & D) and patent spending have become …

Taking The Strict Account Of Techne Seriously: An Interpretive Direction In Plato's Republic, Kenneth Knies

Philosophy, Theology and Religious Studies Faculty Publications

I argue that the strict account of techne agreed to by Socrates and Thrasymachus in Republic I provides a useful framework for addressing a central question of the dialogue as a whole: how philosophy might belong to the polis. This view depends upon three positions: 1) that Plato invites us to interpret the relationship between techne and polis outside the terms of the city-soul analogy, 2) that the strict account contributes to a compelling description of vocational work, and 3) that this description determines what Socrates means by a true polis, and thus frames the problem of philosophy’s political inclusion.

Causes And Consequences Of Diversity Within Experimental Biofilms Of Pseudomonas Aeruginosa, Kenneth Mark Flynn

Doctoral Dissertations

Currently, we do not understand how much biodiversity may be maintained in any environment, especially not in the structured environments of biofilms, which constitute the dominant mode of microbial life. Although maintenance is associated with the complex spatial structure of biofilm architecture and resulting ecological opportunities, how both the abiotic and biotic environment defines available niches remains poorly understood. Here, we experimentally evolved three replicate populations founded by Pseudomonas aeruginosa strain PA14 for 540 generations under conditions favoring a regular cycle of biofilm formation and dispersal. Utilizing a variety of laboratory and genomic sequencing approaches, we characterize the population genetic …

Conserving Wetlands For Humans And Amphibians: A Multidisciplinary Approach To Understanding The Social And Ecological Effectiveness Of New England's Wetland Policies, Jessica Veysey Powell

Doctoral Dissertations

Freshwater wetland ecosystems are a valuable resource, but current policies fail to prevent their continuing destruction. Policy-makers increasingly use decentralized wetland-buffer programs to address such policy failings, but scant research has evaluated whether these programs are both ecologically and socially effective. In the following dissertation, I address this gap using two complementary projects.

For the first project, I assessed whether forested buffers are an effective tool for maintaining viable populations of pool-breeding amphibians. Such species spend their early life stages in vernal pools, which are small, highly productive wetlands, but use the surrounding forest during juvenile and adult life-stages. Though …

Bronze Statuettes From The Athenian Agora: Evidence For Domestic Cults In Roman Greece, Heather F. Sharpe

Art + Design Faculty Publications

No abstract provided.

The End Of Religious Freedom: What Is At Stake?, Nelson Tebbe

Faculty Scholarship

No abstract provided.

Psyx 250n.01: Fundamentals Of Biological Psychology, Erin Yosai

University of Montana Course Syllabi

No abstract provided.

Mart 111a.01m: Integrated Digital Art, Joey N. Walker

University of Montana Course Syllabi

No abstract provided.

Mar 101l.01m: Introduction To Media Arts, Michael R. Murphy

University of Montana Course Syllabi

No abstract provided.

Mart 302.02: Introduction To Motion Design, Wesley S. Meeks

University of Montana Course Syllabi

No abstract provided.