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2013

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Metabolic Engineering Of Flavonoid Biosynthesis In Scutellaria Lateriflora Hairy Roots By Ectopic Expression Of The Atmyb12 Transcription Factor, Tianhong Yang May 2013

Metabolic Engineering Of Flavonoid Biosynthesis In Scutellaria Lateriflora Hairy Roots By Ectopic Expression Of The Atmyb12 Transcription Factor, Tianhong Yang

Student Theses and Dissertations

American skullcap (Scutellaria lateriflora), a perennial herb native to America, is rich in specialized metabolites that have shown various biological activities. In particular, the flavonoids wogonin, baicalein and baicalin have proven anticancer properties in vitro. However, the regulatory mechanisms and biosynthetic steps leading to these specialized metabolites have not been elucidated. To address this issue, hairy root cultures of S. lateriflora expressing the flavonoid-specific transcription factor AtMYB12 from Arabidopsis thaliana were developed using Agrobacterium rhizogenes ATCC 15834 containing a binary vector harboring the AtMYB12 cDNA under the control of the SuperP:TEV expression system. In this study, three AtMYB12 transgenic hairy …

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Predictors For An Autism Spectrum Disorder Diagnosis: A Risk Modeling Endeavor, Cristy S. Phillips May 2013

Predictors For An Autism Spectrum Disorder Diagnosis: A Risk Modeling Endeavor, Cristy S. Phillips

Student Theses and Dissertations

The purpose of this study was to derive one or more single indicators or sets of correlated indicators that could predict a heightened probability for an autism spectrum disorder (ASD) diagnosis, a critical first step in the development of a risk-model. Educators need a risk-model that will identify infants and young children with ASD before their symptoms are fully manifested. Such a model would help educators to fulfill their federal mandate to provide timely identification and early-intervention services, improving long-term outcomes for affected children. Fortunately, advanced statistical modeling techniques and extant early-intervention data suggest a solution: Exploratory latent class factor …

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Partial Incubation, Hatching Asynchrony, And Sibling Aggression In The Red-Shouldered Hawk (Buteo Lineatus), Sara Johnson Miller May 2013

Partial Incubation, Hatching Asynchrony, And Sibling Aggression In The Red-Shouldered Hawk (Buteo Lineatus), Sara Johnson Miller

Student Theses and Dissertations

I used video monitoring to quantify egg-laying intervals, partial incubation, hatching asynchrony, feeding rates, sibling aggression, and causes of mortality or nest failure in a suburban population of Red-shouldered Hawks (Buteo lineatus). The egg-laying interval and parents' partial incubation behavior during egg-laying resulted in a significant correlation between the sum of incubation time during egg-laying and the hatching span (r2 = 0.83, p <0.0001). Hatch rank was the most significant predictor for both the amount of food consumed and the number of aggressive acts displayed by a nestling. First-hatched senior nestlings received significantly more food and were significantly more aggressive than junior nestlings. Broods of three displayed significantly more aggression than broods of two, and aggression decreased significantly from week two to three. There was no significant relationship between the total amount of food consumed and the total amount of aggression in each nest, which rejects the food amount hypothesis.

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The Relationship Between Gender Identity And Flirting Style, Michael Gray May 2013

The Relationship Between Gender Identity And Flirting Style, Michael Gray

Student Theses and Dissertations

This study investigates the relationship between gender identity and flirting styles. Data analysis on a sample (N=227) revealed the existence of a relationship between gender identity and the sincere style and between gender identity and the physical style, but not between gender identity and the playful, polite, and traditional styles. Masculine and Androgynous individuals are more likely than Feminine or Undifferentiated individuals to employ the physical style. Androgynous individuals are more likely to employ the sincere style than masculine or undifferentiated individuals. Feminine individuals are more likely to employ the sincere style than masculine individuals. Further analysis found that there …

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Identification Of Shiga Toxin - Producing Escherichia Coli In Beef Cattle Of Northeast - Arkansas Using Cultural Methods, Harneet Kaur May 2013

Identification Of Shiga Toxin - Producing Escherichia Coli In Beef Cattle Of Northeast - Arkansas Using Cultural Methods, Harneet Kaur

Student Theses and Dissertations

Pathogenic E.coli that produce a class of cytotoxins, called shiga toxin, are known as shiga toxigenic E. coli (STEC). Beef cattle and its products are the main vehicle for STEC transmission. These bacteria cause human illnesses ranging from mild diarrhea to life-threatening diseases such as hemorrhagic colitis, and hemolytic uremic syndrome. The purpose of this study is to use effective methods to determine STEC prevalence in northeast Arkansas. Samples (rectal swabs, feed, soil, and water) were collected from 18 farms. STEC strains were identified using cultural methods involving enrichment, and plating on CT-SMAC and CT-Rainbow agar. Isolate identities were confirmed …

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Microglial Activation By Amyloid-Beta, Geeta Subhash Paranjape May 2013

Microglial Activation By Amyloid-Beta, Geeta Subhash Paranjape

Dissertations

Paranjape, Geeta S.,Ph.D.,University of Missouri-Saint Louis, May 2012. Aβ(1-42) Protofibrils But Not Fibrils Activate Microglia. Major Professor: Michael R. Nichols. One of the hallmark features of the Alzheimer’s disease (AD) brain is the extracellular deposition of amyloid-β protein (Aβ) in both fibrillar (senile plaques) and diffuse forms. Significant proinflammatory markers including activated microglia and cytokines have been detected surrounding the plaques but are absent in diffuse areas suggesting that microglial activation is sensitive to Aβ structure. Since Aβ displays structural polymorphism in vitro, we sought to determine the relationship between Aβ aggregation state and microglial proinflammatory response. Size exclusion chromatography …

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Binding Energies And Solvation Of Organic Molecular Ions, Reactions Of Transition Metal Ions With, And Plasma Discharge Ionization Of Molecular Clusters, Isaac Kwame Attah May 2013

Binding Energies And Solvation Of Organic Molecular Ions, Reactions Of Transition Metal Ions With, And Plasma Discharge Ionization Of Molecular Clusters, Isaac Kwame Attah

Theses and Dissertations

In this dissertation, different approaches have been employed to address the quest of understanding the formation and growth mechanisms of carbon-containing molecular ions with relevance to astrochemistry. Ion mobility mass spectrometry and DFT computations were used to investigate how a second nitrogen in the pyrimidine ring will affect the formation of a covalent bond between the benzene radical cation and the neutral pyrimidine molecule, after it was shown that a stable covalent adduct can be formed between benzene radical cation and the neutral pyridine. Evidence for the formation of a more stable covalent adduct between the benzene radical cation and …

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Soundings 2013-05-03, N/A N/A May 2013

Soundings 2013-05-03, N/A N/A

Soundings

No abstract provided.

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Eastern Kentucky Farmer's Willingness To Grow Biomass For Emergy Production, Austin P. Jacobs May 2013

Eastern Kentucky Farmer's Willingness To Grow Biomass For Emergy Production, Austin P. Jacobs

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Austin P. Jacobs in May of 2013.

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Stepwise Acquisition Of Vocal Combinatorial Capacity In Songbirds And Human Infants, Dina Lipkind, Gary F. Marcus, Douglas Bemis, Kazutoshi Sasahara, Nori Jacoby, Miki Takahashi, Kenta Suzuki, Olga Feher, Primoz Ravbar, Kazuo Okanoya, Ofer Tchernichovski May 2013

Stepwise Acquisition Of Vocal Combinatorial Capacity In Songbirds And Human Infants, Dina Lipkind, Gary F. Marcus, Douglas Bemis, Kazutoshi Sasahara, Nori Jacoby, Miki Takahashi, Kenta Suzuki, Olga Feher, Primoz Ravbar, Kazuo Okanoya, Ofer Tchernichovski

Publications and Research

Human language, as well as birdsong, relies on the ability to arrange vocal elements in novel sequences. However, little is known about the ontogenetic origin of this capacity. We tracked the development of vocal combinatorial capacity in three species of vocal learners, combining an experimental approach in zebra finches with an analysis of natural development of vocal transitions in Bengalese finches and pre-lingual human infants and found a common, stepwise pattern of acquiring vocal transitions across species. In our first study, juvenile zebra finches were trained to perform one song and then the training target was altered, prompting the birds …

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Newroom: Rwu Law Lighting At Waterfire Providence, Roger Williams University School Of Law May 2013

Newroom: Rwu Law Lighting At Waterfire Providence, Roger Williams University School Of Law

Life of the Law School (1993- )

No abstract provided.

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Giant Ants And Killer Children: Fear And Popular Culture In 1950s America, Kathleen Elizabeth Ford May 2013

Giant Ants And Killer Children: Fear And Popular Culture In 1950s America, Kathleen Elizabeth Ford

Masters Theses, 2010-2019

This public history thesis consists of three main sections that combine to form a complete plan for a museum exhibit on 1950s American fears as seen through the lens of popular culture. In American popular memory, postwar America often emerges as a somewhat simplistic time in which every citizen was mired in conservatism and concerned only for communist spies and nuclear devastation. Though these were very real fears for the majority of the population, their fears also went much deeper than this. Through the museum exhibit medium, this thesis explores fears of loneliness, humanity’s capacity for evil, and societal collapse …

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Examining The Effects Of D-Amphetamine On Discounting In Spontaneously Hypertensive Rats (Shr), Daniel Joseph Peterson May 2013

Examining The Effects Of D-Amphetamine On Discounting In Spontaneously Hypertensive Rats (Shr), Daniel Joseph Peterson

Masters Theses, 2010-2019

This experiment examined d-amphetamine’s effect on discounting of delayed and probabilistic outcomes in spontaneously hypertensive rats (SHRs), a purported animal model of Attention Deficit/Hyperactivity Disorder (ADHD), with two control strains. Stimulants such as d-amphetamine are commonly administered in humans diagnosed with ADHD, thus resulting in increases in self-controlled responding on delay tasks. However, very little has been done examining the effects of d-amphetamine on delay tasks using the SHR strain, a purported animal model of ADHD. Recent research has also suggested that responses on delay and probability discounting procedures are mediated by the same underlying mechanism in animal models (Green, …

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To Move Or Not To Move: The Impact Of Instruction On Planning And The Role Of Inhibitory Control, Sarah Anne Marrs May 2013

To Move Or Not To Move: The Impact Of Instruction On Planning And The Role Of Inhibitory Control, Sarah Anne Marrs

Masters Theses, 2010-2019

The purpose of this study was to investigate the impact of instructing 7- and 8-year old children to plan their moves prior to beginning Tower of London (TOL) problems and the degree to which inhibitory control ability was related to performance on the TOL. Half of the sample received explicit instructions to plan their moves while half of the sample did not. The results indicate that the two groups of children do not differ significantly in their TOL performance. Thus, prompting children to use more efficient problem solving strategies may not result in improved problem solving ability. Contrary to previous …

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Supporting The Well Being Of University Student Survivors Of Cancer, Janice Lewis May 2013

Supporting The Well Being Of University Student Survivors Of Cancer, Janice Lewis

Educational Specialist, 2009-2019

Young adult survivors of cancer present a unique set of needs and developmental factors to consider when working to support their well being (physical, mental, emotional, and social health). The experiences of these individuals can vary in many ways. This variety might include variables such as: age of diagnosis, type of cancer, type of treatment, resources available, family support, etc. The intent of this project is to examine and review the needs of young adult university student cancer survivors and address important considerations for professionals working to support their well being. Interviews with cancer survivors and a supportive professional were …

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Current Needs And Response To Suicidal Behavior At The Elementary School Level: A Survey Of Virginia School Psychologists, Kelsey R. Cutchins May 2013

Current Needs And Response To Suicidal Behavior At The Elementary School Level: A Survey Of Virginia School Psychologists, Kelsey R. Cutchins

Educational Specialist, 2009-2019

While minimal information on suicidal behavior at the elementary school level is available, a review of the existing literature demonstrates the erroneous belief that children lack the developmental maturity to understand the concept of death and suicide. To better understand prevalence rates of suicidal behavior in elementary school-aged children, interventions offered to those children, reported levels of practitioner competence, and overall preparedness of elementary school personnel in appropriately addressing suicidal behavior demonstrated by their students, the researcher surveyed 155 Virginia school psychologists. Results from the online survey revealed that while suicidal behavior in elementary school-aged students is rare, school-based professionals …

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Wired To Bond: The Influence Of Computer-Mediated Communication On Relationships, Jennifer Lynn Cline May 2013

Wired To Bond: The Influence Of Computer-Mediated Communication On Relationships, Jennifer Lynn Cline

Dissertations, 2014-2019

The purpose of this study was to examine young adults’ use of social media, qualities of their interpersonal relationships, and the intersection of the two. This primarily qualitative research study set out to investigate the qualities of relationships under the theoretical umbrellas of attachment, existentialism, and neuroscience. In particular, this grounded theory study examined how relationships might differ in on-line and face-to-face interactions, and answered the broad question, “What is the impact of increased engagement with others through computer-mediated communication, which involves less sharing of physical space and real time, on one’s perception of others and self?” The research design …

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Emotion Regulation In European American And Hong Kong Chinese Middle School Children, Kayan Phoebe Wan May 2013

Emotion Regulation In European American And Hong Kong Chinese Middle School Children, Kayan Phoebe Wan

Dissertations, 2014-2019

This study explored emotion regulation strategies in middle school European American (N = 54) and Hong Kong Chinese (N =89) children. Based on Gross’s theory (1998), the Survey of Emotion Regulation Strategies was designed to study children’s perceived effectiveness of emotion regulation strategies (deep breathing, thinking positively, situation avoidance, talking and suppression) in three fictitious scenarios associated with sadness, anger, and fear. Five mixed ANOVAs were conducted to evaluate the effect of culture, gender and the type of emotion on each emotion regulation strategy. The results demonstrated that American children considered deep breathing more effective in dealing with anger than …

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The Potential For Replication And Transmission Of Antibiotic Resistance Plasmids In An E. Coli Population In Agriculturally Impacted Stream Sediment, Erika Gehr May 2013

The Potential For Replication And Transmission Of Antibiotic Resistance Plasmids In An E. Coli Population In Agriculturally Impacted Stream Sediment, Erika Gehr

Masters Theses, 2010-2019

The use of antibiotics in agriculture is thought to be a major cause of resistance in microorganisms found in the environment. Horizontal transfer of genetic information from transient to native and from native to transient bacterial populations may enhance the spread and recombination of resistance genes and might play a role in the formation of multi-resistant organisms in environmental reservoirs. Tetracycline resistance plasmids were compared using three isolation techniques -- traditional “endogenous” extraction from isolates, “exogenous” plasmid capture, and direct plasmid extraction from sediment --to determine the potential for plasmid born resistance in an E. coli population found in agriculturally-impacted …

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Occurrence, Survival, And Persistence Of The Fecal Indicator Bacterium, Enterococcus Mundtii, In Soils Of A Contaminated Watershed, Marc Carpenter May 2013

Occurrence, Survival, And Persistence Of The Fecal Indicator Bacterium, Enterococcus Mundtii, In Soils Of A Contaminated Watershed, Marc Carpenter

Masters Theses, 2010-2019

The Clean Water Act of 1972 raised awareness of the extent of the pollution in U.S. waters and the need for monitoring and identifying sources of contamination. Surface water quality is routinely evaluated using fecal indicators, such as Enterococcus spp. Recent studies in a south Texas watershed showed that fecal bacteria were being transported to water via agricultural land runoff following rainfall, suggesting that soil may be a source of these bacteria. In this study, soils from fields under different crop covers were sampled to determine seasonal levels of enterococci and species of enterococci were identified using the BIOLOG™ Microbial …

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Probiotic Bioaugmentation Of An Anti-Bd Bacteria, Janthinobacterium Lividum, On The Amphibian, Notophthalmus Viridescens: Transmission Efficacy And Persistence Of The Probiotic On The Host And Non-Target Effects Of Probiotic Addition On Ecosystem Components, Molly Bletz May 2013

Probiotic Bioaugmentation Of An Anti-Bd Bacteria, Janthinobacterium Lividum, On The Amphibian, Notophthalmus Viridescens: Transmission Efficacy And Persistence Of The Probiotic On The Host And Non-Target Effects Of Probiotic Addition On Ecosystem Components, Molly Bletz

Masters Theses, 2010-2019

Amphibians worldwide are threatened by the fungal disease chytridiomycosis, caused by the skin pathogen Batrachochytrium dendrobatidis. Mutualistic skin bacteria are a critical element in amphibians’ defenses against chytridiomycosis. Probiotic bioaugmentation of beneficial, anti-Bd bacteria on amphibians is a potential conservation strategies. Outdoor experimental ponds were used to investigate transmission efficacy and persistence of the anti-Bd bacteria, Janthinobacterium lividum, on the amphibian, Notophthalmus viridescens. More specifically, this research investigated whether a short-term individual bath, environmental bioaugmentation, or both are necessary to afford transmission and persistence of J. lividum on N. viridescens. Additionally, this research investigated the effectiveness of these different probiotic …

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A Board Game Simulator For Promoting System Thinking For Sustainable Pastoralism Among Maasai In Southern Kenya, Jacob Loorimirim Mayiani May 2013

A Board Game Simulator For Promoting System Thinking For Sustainable Pastoralism Among Maasai In Southern Kenya, Jacob Loorimirim Mayiani

Masters Theses, 2010-2019

A culturally-anchored board game simulator named ERAMAT! was created in cooperation with faculty members and members of the Maasai community and then piloted with US students and members of Maasai communities in southern Kenya during the summer of 2012. The game provides an alternative to a computer-based simulator, and hence provides a culturally credible simulation of the system dynamics associated with an accelerating boom/bust cycle of drought and hunger in the region. Factors driving the phenomena include greatly increased population densities, pastoralist cultural values, evolving pastoral practices, the ebb and flow of the semi-arid environment in which Maasai pastoralists live, …

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Economic Life Cycle Assessment Of Aeration Blowers Used In Waste Water Treatment Systems, Manogaran Shriram May 2013

Economic Life Cycle Assessment Of Aeration Blowers Used In Waste Water Treatment Systems, Manogaran Shriram

Masters Theses, 2010-2019

Economic Life Cycle Assessment of Aeration Blowers used in Waste Water Treatment systems A substantial amount of energy is needed in water supply and treatment systems to convert the unprocessed water into safe drinking water or to purify wastewater prior to discharge to the environment. There is lot of water and energy lost in the process of collection, discharge and delivery of the treated drinking water as well. Therefore the energy and water consumption by these systems have an indirect effect on the local municipality in terms of high energy consumption and in permissive waste of water. Thus, an exhaustive …

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Agricultural/Forestal Districts: Surveying Afd Landowners In Augusta County And The City Of Staunton To Determine Areas For Program Improvement And Program Promotion Strategies, Martin Driver May 2013

Agricultural/Forestal Districts: Surveying Afd Landowners In Augusta County And The City Of Staunton To Determine Areas For Program Improvement And Program Promotion Strategies, Martin Driver

Masters Theses, 2010-2019

Agricultural/Forestal Districts (AFDs) are rural conservation zones reserved for the production of agricultural products and function to protect agricultural and forestal lands as important natural resources. These districts are formed voluntarily by Virginia landowners and provide a number of important benefits to the landowners and surrounding communities. From a stewardship and administration standpoint, it would benefit both landowners and administrators to determine areas needing improvement within the AFD program. Also, it would be beneficial to these same parties to determine optimal methods for promoting the program to landowners who are not currently AFD members. The evaluation and understanding of these …

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The Identity Of Rana Margaritifera Laurenti, 1768 (Anura, Bufonidae), Esteban O. Lavilla, Ulisses Caramaschi, José A. Langone, José P. Pombal Jr., Rafael O. De Sá May 2013

The Identity Of Rana Margaritifera Laurenti, 1768 (Anura, Bufonidae), Esteban O. Lavilla, Ulisses Caramaschi, José A. Langone, José P. Pombal Jr., Rafael O. De Sá

Biology Faculty Publications

Rana margaritifera was described by Laurenti in 1768 and currently is associated to the genus Rhinella, under the combination Rhinella margaritifera. Currently, the R. margaritifera species group consists of 16 recognized species. Further-more, many additional species have been suggested to exist in this group which highlights the ambiguity surrounding the identity of Rhinella margaritifera and impend further description of the species in this group. After an exhaustive bibliographic review, we concluded that the recent designation of a lectotype for R. margaritifera is invalid according with Art. 73, ICZN, 1999. Herein, we designate and provide the description of a …

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Oral Contraceptives, Stephenie G. Fortier May 2013

Oral Contraceptives, Stephenie G. Fortier

Senior Honors Theses

Cyclic oral contraceptive and continuous oral contraceptives have many similarities yet a few distinct differences. One of the major differences between cyclic and continuous oral contraceptives is that cyclic oral contraceptive pills have twenty one active pills and seven inactive pills versus the new continuous oral contraceptive pills which have 28 active pills and no inactive pills. However, though cyclic and continuous oral contraceptives do have a few differences, both types of oral contraceptives affect a woman’s body in similar ways. When choosing between cyclic and continuous oral contraceptives, it is important for women to be informed about the advantages …

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The New Hampshire, Vol. 102 [103], No. 49 (May 3, 2013), The New Hampshire May 2013

The New Hampshire, Vol. 102 [103], No. 49 (May 3, 2013), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 102, but it is the 103rd volume in the series. This was corrected in pencil.

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Oxygen Tomography By Čerenkov-Excited Phosphorescence During External Beam Irradiation, Rongxiao Zhang, Scott C. Davis, Jennifer-Lynn H. Demers, Adam K. Glaser, David J. Gladstone, Tatiana V. Esipova, Sergei A. Vinogradov, Brian W. Pogue May 2013

Oxygen Tomography By Čerenkov-Excited Phosphorescence During External Beam Irradiation, Rongxiao Zhang, Scott C. Davis, Jennifer-Lynn H. Demers, Adam K. Glaser, David J. Gladstone, Tatiana V. Esipova, Sergei A. Vinogradov, Brian W. Pogue

Dartmouth Scholarship

The efficacy of radiation therapy depends strongly on tumor oxygenation during irradiation. However, current techniques to measure this parameter in vivo do not facilitate routine monitoring in patients. Herein, we demonstrate a noninvasive method for tomographic imaging of oxygen partial pressure (pO2 ) in deep tissue using the phosphorescence decay of an oxygen-sensitive probe excited by Čerenkov radiation induced by external beam radiotherapy. Tissue-simulating scattering phantoms (60 mm diameter with a 20 mm anomaly) containing platinum(II)-G4 (PtG4), a dendritic porphyrin-based phosphor, whose phosphorescence is quenched in the presence of oxygen, were irradiated with a clinical linear accelerator. The …

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Anne Weston Mcgowan, Anne Mcgowan '76, Abigail Szunyogh 2014 May 2013

Anne Weston Mcgowan, Anne Mcgowan '76, Abigail Szunyogh 2014

All oral histories

Anne Weston McGowan graduated with a BA in English in 1976. She moved to Bloomington-Normal when her husband James joined the English Department faculty in 1969. Anne is a former Board member of the community organization Ecology Action Center (founded in 1971 and called Operation Recycle). She remains active in that and other community organizations.

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James Mcgowan, James Mcgowan, Elissa Ledvort 2013 May 2013

James Mcgowan, James Mcgowan, Elissa Ledvort 2013

All oral histories

James McGowan, Professor of English Emeritus, joined IWU's faculty in 1969 and retired in 2000. He and Anne (Class of 1976) remain active in the community. Dr. McGowan read his original poem commemorating the inauguration of IWU's 15th President Richard F. Wilson may be found at http://digitalcommons.iwu.edu/wilson_inauguration/15

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