Digital Commons Network^™

An Hsus Report: Industrial Farm Animal Production And Livestock Associated Mrsa (Methicillin Resistant Staphylococcus Aureus), The Humane Society Of The United States

Impact of Animal Agriculture

Staphylococcus aureus is a leading cause of bacterial infection and is increasingly found to be resistant to antibiotic therapy. A newly described type of Methicillin Resistant Staphylococcus aureus carried by farm animals, Livestock Associated MRSA (LA-MRSA), is now causing infections in humans with and without direct livestock contact. A reduction in the non-therapeutic use of antibiotics in feed would likely reduce the capacity of industrial animal agriculture to continue to create, disseminate, and perpetuate a large reservoir of LA-MRSA on a global scale, but more fundamental changes in the way animals are raised for food may be necessary forestall a …

Industrial Farm Animal Production And Livestock Associated Mrsa (Methicillin Resistant Staphylococcus Aureus)

Agribusiness Reports

Staphylococcus aureus is a leading cause of bacterial infection and is increasingly found to be resistant to antibiotic therapy. A newly described type of Methicillin Resistant Staphylococcus aureus carried by farm animals, Livestock Associated MRSA (LA-MRSA), is now causing infections in humans with and without direct livestock contact. A reduction in the non-therapeutic use of antibiotics in feed would likely reduce the capacity of industrial animal agriculture to continue to create, disseminate, and perpetuate a large reservoir of LA-MRSA on a global scale, but more fundamental changes in the way animals are raised for food may be necessary forestall a …

Illuminated Magazine, School Of Graduate Studies, East Tennessee State University

Illuminated: Graduate Student Research Magazine

Super Plants [Biology, M.S. (Biology Concentration) Graduate Student: Richard Sante]; Where Are They Now? [Neal Calvin Peterson]; Navigating Through Financial Aid [a Step-By-Step Guide]; Pregnancy and Violence in Appalachia [Psychology, Experimental Psychology Concentration, Ph.D. Graduate Student: Tifani Fletcher]; Where Are They Now? [Dr. Margie Tucker]; Nutrition and Dentistry [Clinical Nutrition, M.S. Graduate Student: Monique Richard]; Where Are They Now? [Meylin Mejia]; What Are You Looking At? [Professional Communication, M.A. Graduate Student: Mariam Ayad]; Research Grant Awards [2013-2014]

The College Of Pharmacy, South Dakota State University

Jackrabbits Script and Scope (Formerly called College of Pharmacy and Allied Health Professions Magazine)

[Page] 2 Endowed professorship created A trust created by a pharmacist who never attended college is providing the funds for the college’s first endowed professorship.
[Page] 3 Berry power The inaugural speaker at the Francis Miller Lecture extols the value of blueberries in fighting cancer — and he’s got the research to prove it. [Page] 4 Medication safety Deidra Van Gilder and Tasha Rausch are part of a national effort to curb medication mistakes through the Patient and Clinical Pharmacy Service Collaborative.
[Page] 6 Ashley Potter The P3 student took a rather indirect route to leadership in a student pharmaceutical …

Research Credit: A Journey Of Uncertainty, Lisa Pan

The Contemporary Tax Journal

No abstract provided.

Resveratrol And Its Metabolites Modulate Cytokine-Mediated Induction Of Eotaxin-1 In Human Pulmonary Artery Endothelial Cells, Joseph M. Wu, Tze-Chen Hsieh, Ching-Jen Yang, Susan C. Olson

NYMC Faculty Publications

Coronary heart disease (CHD) is a leading cause of death in many developed countries. Evidence has long implicated endothelial injury and inflammation as apical events in the pathogenesis of atherosclerosis, the primary cause of CHD. Numerous risk factors contribute to a damaged, inflamed endothelium. Conversely, cardioprotective agents targeting the dysfunctional endothelium have also been identified, notably from dietary sources. We have used cultured human pulmonary artery endothelial cells (HPAECs) to test the diet-mediated cardioprotective hypothesis. In this review, we summarize our recent findings on control of transcription and expression of inflammation biomarker eotaxin-1 in HPAECs exposed to single or combined …

Β-Adrenergic Blockade In Cardiovascular Disease, William H. Frishman

NYMC Faculty Publications

The development and subsequent clinical application of the β-adrenergic receptor blocking drugs represent one of the major advances in human pharmacotherapeutics. No other class of synthetic drugs has demonstrated such widespread therapeutic utility for the treatment and prevention of so many cardiovascular diseases. In addition, these drugs have proven to be molecular probes that have contributed to our understanding of the disease, and on the molecular level, both the structure and function of the 7 transmembrane G protein receptors that mediate the actions of many different hormones, neurotransmitters, and drugs. The evolution of β-blocker drug development has led to refinements …

Transcriptome Profiling Of Hippocampal Ca1 After Early-Life Seizure-Induced Preconditioning May Elucidate New Genetic Therapies For Epilepsy, L K. Friedman, J Mancuso, A Patel, V Kudur, J R. Leheste, S Iacobas, J Botta, D A. Iacobas, D C. Spray

NYMC Faculty Publications

Injury of the CA1 subregion induced by a single injection of kainic acid (1 × KA) in juvenile animals (P20) is attenuated in animals with two prior sustained neonatal seizures on P6 and P9. To identify gene candidates involved in the spatially protective effects produced by early-life conditioning seizures we profiled and compared the transcriptomes of CA1 subregions from control, 1 × KA- and 3 × KA-treated animals. More genes were regulated following 3 × KA (9.6%) than after 1 × KA (7.1%). Following 1 × KA, genes supporting oxidative stress, growth, development, inflammation and neurotransmission were upregulated (e.g. Cacng1, …

Evaluating Itpr-Dependence Of Apoptotic Signaling From The Endoplasmic Reticulum, Agustin Vargas, Jay L. Brewster

Featured Research

Stress within the endoplasmic reticulum (ER) can be induced by misfolded proteins accumulating in the lumen of this organelle. Signaling of ER stress to other parts of the cell results in altered gene expression, physiological adaptation, and with sustained stress, apoptosis (cell suicide). ER stress is often studied with highly toxic compounds that create severe ER stress rapidly, and a condition that is likely not physiologically relevant within an organism. In this study, we examine the apoptotic signaling induced by moderate ER stress, and in particular the inositol 1,4,5-trisphosphate receptor (ITPR). The ITPR regulates Ca2+ release from the ER lumen, …

Lysophosphatidic Acid Stimulates Lymphangiogenesis In Human Lymphatic Endothelial Cells, John Macbeth, Donna Nofziger-Plank

Featured Research

Lymphangiogenesis is the process by which new lymphatic vessels sprout and grow from existing vessels whether under developmental, immunological, or cancerous conditions. Proper lymphatic vessel formation is important in working alongside normal angiogenesis in order to help regulate the body’s tissue fluid as well as aid in immunosurveillance. Various factors regulate lymphangiogenesis such as members of the vascular endothelial growth factor family (VEGF). Another factor that has recently been identified to play a role in lymphangiogenesis is the bio-active phospholipid lysophosphatidic acid (LPA) however the molecular mechanism by which LPA regulates lymphangiogenesis has not been well characterized. In this study, …

Leaf Mechanical Strength Corresponds To Water Relations In Twelve Species Of California Ferns, Breahna Gillespie

Featured Research

Mentor: Stephen D. Davis

In angiosperms and gymnosperms, mechanically strong leaves are positively correlated with dehydration-tolerance. In general, leaves that are stronger mechanically tend to be evergreen while those that are not are usually mechanically weak and deciduous in response to water stress. Avoiding water stress, especially in a chaparral Mediterranean-type climate, which receives less than 500 mm of water per year, requires energy-intensive adaptation. Ferns residing in the chaparral are presumed to adopt a similar strategy: either they maintain or abscise their pinnae in drought. It was reasoned that ferns with lower water potential and able to survive in …

An Ethnobotanical Approach To Finding Antimicrobial Compounds In Wooly Blue Curls (Trichostema Lanatum) Using A Kirby-Bauer Disc Diffusion Assay, Matthew C. Fleming, P. Matthew Joyner

Featured Research

Plants can be an important source of creativity and production of new drugs. In this study, extracts of wooly blue curls (Trichostema lanatum) were made using DMSO and tested for antimicrobial activity on a panel of bacteria commonly found in separate ecological niches. Wooly blue curls (WBC) was chosen due to its being recorded as a strong disinfectant by the Chumash people. It was found that WBC does exhibit antimicrobial activity against gram positive bacteria and not against gram negative bacteria. However, gram negative bacteria with reduced drug efflux function became susceptible to the WBC extract.

Minor Fitness Benefits For Edge Avoidance In Nesting Grassland Birds In The Northeastern United States, David G. Perkins, Noah G. Perlut, Allan M. Strong

Environmental Studies Faculty Publications

Grassland birds are often affected negatively by habitat fragmentation. Outcomes include greater nest predation and brood parasitism, decreased colonization rates of small, isolated patches, and greater nest density in remnant core habitats. These effects have been well documented in the Midwest, but little is known about fragmentation and edge effects on grassland birds in the fragmented agricultural fields within the forested landscapes of the northeastern United States. From 2002 to 2010, we assessed how edges and edge types affected nest-site location and daily nest survival (DNS) of Savannah Sparrows (Passerculus sandwichensis) and Bobolinks (Dolichonyx oryzivorus) breeding …

Religion And Spiritual Experience: Revisiting Key Assumptions In Sociology, Steven F. Cohn, Kyriacos C. Markides

International Journal of Transpersonal Studies

In this paper, we examine the dominant materialist assumption that there is an inherent conflict between sociology, religion, and spirituality. We will suggest that such a conflict is not fundamental and that accepting the possibility that religious experiences might reflect contact with a transcendent reality can enrich the theoretical possibilities of sociology, supplementing rather than replacing existing insights.

A Declaration Of Interdependence: Peace, Social Justice, And The “Spirit Wrestlers”, John Elfers

International Journal of Transpersonal Studies

The struggle between the Doukhobors, a nonviolent society committed to communal values, and the Canadian Government epitomizes the tension between values of personal rights and independence on the one hand, and social obligation on the other. The immigration of the Doukhobors from Russia to the Canadian prairies in 1899 precipitated a centurylong struggle that brings issues of social justice, moral obligation, political authority, and the rule of law into question. The fundamental core of Western democracies, founded on the sanctity of individual rights and equal opportunity, loses its potency in a community that holds to the primacy of interdependence and …

Carbon Black And Titanium Dioxide Nanoparticles Differentially Activate Oxidative Stress And Apoptosis In A549 Human Alveolar Epithelial Cells, Sarah Alvarado, Brianna Manes, Jay L. Brewster

Featured Research

Recent studies have demonstrated that variation between particulate matter compositions have universally adverse effects on cells and living tissues. Carbon black and titanium dioxide are two such particulates that we are continuously exposed to, yet there is limited research to examine the potential deleterious effects on living tissue. The objective of this study is to characterize the effect of carbon black (CB) and titanium dioxide (TiO2) particulates on A549 human alveolar epithelial lung cells. CB and TiO2 powders were dispersed throughout a solution of water and bovine serum albumin by high-powered sonication. The effects of these particulates on A549 cells …

Policy On Restocking And Stock Enhancement In Western Australia, Department Of Fisheries Western Australia.

Fisheries Management Papers

The practice of releasing hatchery-reared fish into existing populations to augment fishing (stock enhancement) or restore depleted spawning biomass (restocking) has occurred around the world for decades with varying degrees of success. The underpinning concept is to produce and release fish into wild populations to increase their abundance, catch rates and/or fishery yields

If restocking and stock enhancement activities are to be successful, they should have clear objectives and be well planned and targeted at situations where there is a reasonable expectation of having a beneficial effect.

Plant Micrornas Display Differential 3' Truncation And Tailing Modifications That Are Argonaute1 Dependent And Conserved Across Species, Jixian Zhai, Yuanyuan Zhao, Stacey A. Simon, Sheng Huang, Katherine Petsch, Siwaret Arikit, Manoj Pillay, Lijuan Ji, Meng Xie, Xiaofeng Cao, Bin Yu, Marja Timmermans, Bing Yang, Xuemei Chen, Blake C. Meyers

Center for Plant Science Innovation: Faculty Publications

Plant small RNAs are 3' methylated by the methyltransferase HUA1 ENHANCER1 (HEN1). In plant hen1 mutants, 3' modifications of small RNAs, including oligo-uridylation (tailing), are associated with accelerated degradation of microRNAs (miRNAs). By sequencing small RNAs of the wild type and hen1 mutants from Arabidopsis thaliana, rice (Oryza sativa), and maize (Zea mays), we found 39 truncation prior to tailing is widespread in these mutants. Moreover, the patterns of miRNA truncation and tailing differ substantially among miRNA families but are conserved across species. The same patterns are also observable in wild-type libraries from a broad …

Environmental Factors Associated With Toxic Cyanobacteria In Pinto Lake, A Coastal Lake In The Monterey Bay Area, Erin Stanfield

SNS Master's Theses

Cyanobacterial harmful algal blooms (CHABs) dominate and disrupt aquatic ecosystems by virtue of their rapidly expanding biomass and the production of secondary metabolites, including potent toxins. Since 2007, toxin-producing CHABs have been documented in freshwater bodies draining into the Monterey Bay National Marine Sanctuary (MBNMS) located on the California Central Coast. In this study, we combined freshwater ecology and molecular biology approaches to characterize the abundance of potentially toxic cyanobacteria, intracellular microcystin levels, and presence of microcystin synthesis genes in association with environmental factors in Pinto Lake, located in Watsonville, CA, a freshwater body seasonally draining into the MBNMS. We …

Benchmarks 2013, July 26, The Rockefeller University

BenchMarks 2013

BenchMarks. Friday, July 26, 2013

The community newsletter of The Rockefeller University

BenchMarks is published monthly and is distributed on the campus of The Rockefeller University. It produced by the Office of Communications and Public Affairs

Action Items, Wku Graduate Council

Graduate School

Overview of action items handled by the Graduate Council.

Toni M. Conley - An Empirical Analysis Of How Purchase Decision Makers Arrive At A Fair Price For Subscription-Based Crm, Toni M. Conley

Ronald E. McNair Scholars Program 2013

Internet based technologies have played an important role in the development of modern CRM applications over the last several years. They have been the critical driving force behind the rise of on-demand CRM, and have also enabled on-premise CRM vendors to dramatically simplify deployment and administration. As a result of this, business purchase decision makers are in the midst of a recent and accelerating shift in how they acquire marketing support solutions for their enterprises. They are moving from a CAPEX (capital expenditure) to an OPEX (operational expenditure) model. Many time, marketing support solutions acquired via an on-demand model (OPEX) …

Will Hubbard Brook Soils Be A Source Or Sink Of Carbon In A Changing Climate?, Chris E. Johnson

Civil and Environmental Engineering - All Scholarship

No abstract provided.

You've Gotta Read This: Summer Reading At Musselman Library (2013), Musselman Library

You’ve Gotta Read This: Summer Reading at Musselman Library

Each year Musselman Library asks Gettysburg College faculty, staff, and administrators to help create a suggested summer reading list to inspire students and the rest of the campus community to take time in the summer to sit back, relax, and read. These summer reading picks are guaranteed to offer much adventure, drama, and fun!

A Mathematical Model And Numerical Method For Thermoelectric Dna Sequencing, Liwei Shi

Doctoral Dissertations

DNA sequencing is the process of determining the precise order of nucleotide bases, adenine, guanine, cytosine, and thymine within a DNA molecule. It includes any method or technology that is used to determine the order of the four bases in a strand of DNA. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery. Thermoelectric DNA sequencing is a novel method to sequence DNA by measuring the heat that is released when DNA polymerase inserts a deoxyribonucleoside triphosphate into a growing DNA strand. The thermoelectric device for this project is composed of four parts: …

"The Library Is Like Her House": Reimagining Youth Of Color In Lis Discourses, Kafi D. Kumasi

School of Information Sciences Faculty Research Publications

No abstract provided.

Transpersonal Sociology: Origins, Development, And Theory, Ryan Rominger, Harris L. Friedman

International Journal of Transpersonal Studies

Transpersonal theory formally developed within psychology through the initial definition of the field in the publishing of the Journal of Transpersonal Psychology. However, transpersonal sociology also developed with the Transpersonal Sociology Newsletter, which operated through the middle 1990s. Both disciplines have long histories, while one continues to flourish and the other, comparatively, is languishing. In order to encourage renewed interest in this important area of transpersonal studies, we discuss the history, and further define the field of transpersonal sociology, discuss practical applications of transpersonal sociology, and introduce research approaches that might be of benefit for transpersonal sociological researchers and practitioners.

Pharmacy Matters - July 2013, University Of Mississippi. School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: "Pharmacy school creates scholarship to honor Marvin Wilson," "Two students sponsor a child after mission trip," "Book teaches pharmacists how to fill health care gap," "Researcher receives Lifetime Achievement Award," "Educational foundation establishes scholarship in alum's memory," "Pharmacognosist garners medals for natural products research"

"Every 'One' And Every 'Thing' Can Be Loved": A Rhetorical Analysis Of Networked Self-Representation By The Objectùm Sexuality Community, Kristen L. Cole

Communication ETDs

Using rhetorical criticism informed by actor-network theory (ANT), in this dissertation I explore the emergence of queer identity and queer community building within the Objectùm Sexuality Internationale Web site (OSI)--the largest source of information related to a community of over 300 hundred individuals who experience emotional and romantic desire towards objects. My goals in this study are (1) to identify and understand how rhetorical strategies are emergent and networked (rather than individually enacted) within the OSI Web site; and (2) how these emergent rhetorical strategies promote multiplicity of sexual desire and identity through the challenging of heteronormative and anthropocentric binaries …

Putting Regulatory Data To Work At The Service Of Public Health: Utilizing Data Collected Under The Clean Water Act, Jyotsna S. Jagai, Barbara J. Rosenbaum, Suzanne M. Pierson, Lynne C. Messer, Kristen M. Rappazzo, Elena N. Naumova, Danelle T. Lobdell

Community Health Faculty Publications and Presentations

Under the Clean Water Act, the US Environmental Protection Agency (EPA) collects information from states on intended use and impairment of each water body. We explore the feasibility of using these data, collected for regulatory purposes, for public health analyses. Combining EPA impairment data and stream hydrology information we estimated the percent of stream length impaired for any use, recreational use, or drinking water use per county in the US as exposure variables. For health outcomes we abstracted county-level hospitalization rates of gastrointestinal infections, GI (ICD-9CM 001-009 excluding 008.45) and gastrointestinal symptoms, GS (ICD-9CM 558.9, 787) among US adults aged …