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Full-Text Articles in Entire DC Network
Usable Security For Wireless Body-Area Networks, Cory Cornelius
Usable Security For Wireless Body-Area Networks, Cory Cornelius
Dartmouth College Ph.D Dissertations
We expect wireless body-area networks of pervasive wearable devices will enable in situ health monitoring, personal assistance, entertainment personalization, and home automation. As these devices become ubiquitous, we also expect them to interoperate. That is, instead of closed, end-to-end body-worn sensing systems, we envision standardized sensors that wirelessly communicate their data to a device many people already carry today, the smart phone. However, this ubiquity of wireless sensors combined with the characteristics they sense present many security and privacy problems. In this thesis we describe solutions to two of these problems. First, we evaluate the use of bioimpedance for recognizing …
Framing Preglimony: Exploring The Implications Of Pregnancy Support Models Through Family Law Values, Candice Marie Reder
Framing Preglimony: Exploring The Implications Of Pregnancy Support Models Through Family Law Values, Candice Marie Reder
Duke Journal of Gender Law & Policy
No abstract provided.
Metadata Services, Sai Deng
Metadata Services, Sai Deng
Faculty Scholarship and Creative Works
No abstract provided.
Biotic Potential And Reproductive Parameters Of Spodoptera Eridania (Stoll) (Lepidoptera, Noctuidae) In The Laboratory, Débora G. Montezano, Alexandre Specht, Daniel Ricardo Sosa-Gómez, Vânia F. Roque-Specht, Neiva M. Barros
Biotic Potential And Reproductive Parameters Of Spodoptera Eridania (Stoll) (Lepidoptera, Noctuidae) In The Laboratory, Débora G. Montezano, Alexandre Specht, Daniel Ricardo Sosa-Gómez, Vânia F. Roque-Specht, Neiva M. Barros
Department of Entomology: Faculty Publications
Biotic potential and reprodutcive parameters of Spodoptera eridania (Stoll) (Lepidoptera, Noctuidae) in the laboratory: This study aimed to evaluate the biotic potential and reproductive parameters of Spodoptera eridania (Stoll, 1782) under controlled conditions (25 ± 1°C, 70 ± 10% RH and 14 hour photophase). The longevity, pre-, post- and oviposition periods, fecundity and fertility of 15 couples was evaluated. The longevity of females (10.80 days) was not significantly higher than those of males (9.27 days). The mean durations of the pre, post and oviposition periods were 2.067, 0.600 and 8.133 days, respectively. The mean fecundity per female was 1,398 eggs …
Retention Of Structure, Antigenicity, And Biological Function Of Pneumococcal Surface Protein A (Pspa) Released From Polyanhydride Nanoparticles, Shannon L. Haughney, Latrisha K. Petersen, Amy D. Schoofs, Amanda Ramer-Tait, Janice King, David Briles, Michael J. Wannemuehler, Balaji Narasimhan
Retention Of Structure, Antigenicity, And Biological Function Of Pneumococcal Surface Protein A (Pspa) Released From Polyanhydride Nanoparticles, Shannon L. Haughney, Latrisha K. Petersen, Amy D. Schoofs, Amanda Ramer-Tait, Janice King, David Briles, Michael J. Wannemuehler, Balaji Narasimhan
Department of Food Science and Technology: Faculty Publications
Pneumococcal surface protein A (PspA) is a choline-binding protein which is a virulence factor found on the surface of all Streptococcus pneumoniae strains. Vaccination with PspA has been shown to be protective against a lethal challenge with S. pneumoniae, making it a promising immunogen for use in vaccines. Herein, the design of a PspA-based subunit vaccine using polyanhydride nanoparticles as a delivery platform is described. Nanoparticles based on sebacic acid (SA), 1,6-bis-(p-carboxyphenoxy)hexane (CPH) and 1,8-bis-(p-carboxyphenoxy)-3,6- dioxaoctane (CPTEG), specifically 50:50 CPTEG:CPH and 20:80 CPH:SA, were used to encapsulate and release PspA. The protein released from the nanoparticle …
Kshv Encoded Rta Induces Cell Cycle Arrest, Pankaj Kumar, Charles Wood
Kshv Encoded Rta Induces Cell Cycle Arrest, Pankaj Kumar, Charles Wood
Nebraska Center for Virology: Faculty Publications
The Kaposi's sarcoma-associated herpesvirus (KSHV) encoded immediate early gene, replication and transcription activator (K-Rta) is a key viral protein that serves as the master regulator for viral lytic replication. In this study, we investigated the role of K-Rta in cell cycle regulation and found that the expression of K-Rta in doxycycline (Dox)-inducible BJAB cells induced cell cycle arrest in G0/G1 phase. Western blot analysis of key cell cycle regulators revealed that K-Rta mediated cell cycle arrest was associated with a decrease in Cyclin A and phosphorylated Rb (pS807/ pS811) protein levels, both markers of S phase progression and an increase …
Therapeutic Modalities In Systemic Lupus Erythematosus, Naveen K. Tyagi, Robert G. Lahita
Therapeutic Modalities In Systemic Lupus Erythematosus, Naveen K. Tyagi, Robert G. Lahita
Saudi Medical Journal
Systemic lupus erythematosus (SLE) is a complex autoimmune disease with significant clinical heterogeneity. Its pathogenesis is complex and involves multigenic components, dysregulation of T and B lymphocytes and the presence of autoantibodies, which form the basis for inflammation, and the pathology found in the various organ systems. Traditional treatments for SLE have included non-steroidal anti-inflammatory drugs, antimalarials, corticosteroids, and cytotoxic/immunosuppressants, but a recent emphasis on the development of biological agents that inhibit autoreactive B cells, interrupt cytokine signaling and facilitate the development of regulatory T cells has become a new modality in treating the disease. This review will delve into …
Climate Change And North American Rangelands: Assessment Of Mitigation And Adaptation Strategies, Linda A. Joyce, David D. Briske, Joel R. Brown, H. Wayne Polley, Bruce A. Mccarl, Derek W. Bailey
Climate Change And North American Rangelands: Assessment Of Mitigation And Adaptation Strategies, Linda A. Joyce, David D. Briske, Joel R. Brown, H. Wayne Polley, Bruce A. Mccarl, Derek W. Bailey
United States Department of Agriculture, Forest Service / University of Nebraska-Lincoln: Faculty Publications
Recent climatic trends and climate model projections indicate that climate change will modify rangeland ecosystem functions and the services and livelihoods that they provision. Recent history has demonstrated that climatic variability has a strong influence on both ecological and social components of rangeland systems and that these systems possess substantial capacity to adapt to climatic variability. Specific objectives of this synthesis are to: 1) evaluate options to mitigate greenhouse gas emissions and future climate change; 2) survey actions that individuals, enterprises, and social organizations can use to adapt to climate change; and 3) assess options for system transformation when adaptation …
Real-Time Quantitative Pcr Assays For Evaluation Of Soybean Varieties For Resistance To The Stem And Root Rot Pathogen Phytophthora Sojae, Mursel Catal, Fedai Erler, Dennis W. Fullbright, Gerard C. Adams
Real-Time Quantitative Pcr Assays For Evaluation Of Soybean Varieties For Resistance To The Stem And Root Rot Pathogen Phytophthora Sojae, Mursel Catal, Fedai Erler, Dennis W. Fullbright, Gerard C. Adams
Department of Plant Pathology: Faculty Publications
Phytophthora root and stem rot caused by Phytophthora sojae is one of the most destructive disease of soybeans in the world. Effective management of the disease depends on selection and use of soybean varieties resistant to the disease. Fast and reliable procedures are vital to screen soybean varieties against the pathogen. Novel real-time quantitative (qPCR) assays were developed for both absolute and relative quantification of P. sojae in infected root tissues. QPCR assays were based on the detection of the internal transcribed spacer (ITS) gene of the pathogen and 18S ribosomal gene of the host plant. Absolute qPCR allowed the …
Food, Parasites, And Epidemiological Transitions: A Broad Perspective, Karl Reinhard, Luis Fernando Ferreira, Françoise Bouchet, L. Sianto, J. M.F. Dutra, A. Iniguez, Daniela Leles, M. Le Bailley, Martín Horacio Fugassa, Elisa Pucu, Adauto Araújo
Food, Parasites, And Epidemiological Transitions: A Broad Perspective, Karl Reinhard, Luis Fernando Ferreira, Françoise Bouchet, L. Sianto, J. M.F. Dutra, A. Iniguez, Daniela Leles, M. Le Bailley, Martín Horacio Fugassa, Elisa Pucu, Adauto Araújo
Karl Reinhard Publications
Pathoecology provides unique frameworks for understanding disease transmission in ancient populations. Analyses of Old and New World archaeological samples contribute empirically to our understanding of parasite infections. Combining archaeological and anthropological data, we gain insights about health, disease, and the way ancient people lived and interacted with each other and with their environments. Here we present Old and New World parasite evidence, emphasizing how such information reflects the different ways ancient populations exploited diverse environments and became infected with zoonotic parasites. It is clear that the most common intestinal helminthes (worm endoparasites) were already infecting ancient inhabitants of the New …
Sensory-Specific Appetition: Postingestive Detection Of Glucose Rapidly Promotes Continued Consumption Of A Recently Encountered Flavor, Kevin P. Myers, Marisa S. Taddeo, Emily K. Richards
Sensory-Specific Appetition: Postingestive Detection Of Glucose Rapidly Promotes Continued Consumption Of A Recently Encountered Flavor, Kevin P. Myers, Marisa S. Taddeo, Emily K. Richards
Faculty Journal Articles
It is generally thought that macronutrients stimulate intake when sensed in the mouth (e.g., sweet taste) but as food enters the GI tract its effects become inhibitory, triggering satiation processes leading to meal termination. Here we report experiments extending recent work (see [1]) showing that under some circumstances nutrients sensed in the gut produce a positive feedback effect, immediately promoting continued intake. In one experiment, rats with intragastric (IG) catheters were accustomed to consuming novel flavors in saccharin daily while receiving water infused IG (5 ml/15 min). The very first time glucose (16% w/w) was infused IG instead of water, …
Bulletin Ninth District Ny September 2013
Bulletin Ninth District Ny September 2013
Bulletin of the Ninth District Dental Association
The Bulletin of the Ninth District Dental Association is published four times annually in the months of March, May, September and November. It is distributed to all Association members from the counties of Dutchess, Orange, Putnam, Rockland and Westchester in the state of New York.
The Bulletin keeps our members up-to-date on NDDA activities as well as on a variety of topics important to the profession.
Force Sensing Surgical Scissor Blades Using Fibre Bragg Grating Sensors, Dean Callaghan
Force Sensing Surgical Scissor Blades Using Fibre Bragg Grating Sensors, Dean Callaghan
Doctoral
This thesis considers the development and analysis of unique sensorised surgical scissor blades for application in minimally invasive robotic surgery (MIRS). The lack of haptic (force and tactile) feedback to the user is currently an unresolved issue with modern MIRS systems. This thesis presents details on smart sensing scissor blades which enable the measurement of instrument-tissue interaction forces for the purpose of force reflection and tissue property identification. A review of current literature established that there exists a need for small compact, biocompatible, sterilisable and robust sensors which meet the demands of current MIRS instruments. Therefore, the sensorised blades exploit …
Conversion Of Greenhouse Gasses Into Energy, Sarah C. Rippe
Conversion Of Greenhouse Gasses Into Energy, Sarah C. Rippe
Social Sciences
No abstract provided.
What A Girl Wants: Female Mate Selection In Terms Of Monetary Resources And Number Of Children, Stefanit Tucker
What A Girl Wants: Female Mate Selection In Terms Of Monetary Resources And Number Of Children, Stefanit Tucker
Modern Psychological Studies
Several evolutionary theories provide the framework for assessing modern mate selection. Previous research in female mate selection has left a gap in whether and how number of children a male has can impact the perception of monetary resources he possesses and subsequently his desirability as a mate. The present investigation thus set out to examine resource-related differences among males with average ($50,001-75,000) and above average incomes (>$150,000) by analyzing data available through the online dating website, match.com. Furthermore, the geographic locations of New York, New York and Louisville, Kentucky were used to both refine results but also maintain genera …
An Introspective Analysis Of The Etiological Relationships Of Psychopathy In Serial Killers And Successful Business Men, Krystina L. Quow
An Introspective Analysis Of The Etiological Relationships Of Psychopathy In Serial Killers And Successful Business Men, Krystina L. Quow
Modern Psychological Studies
Ted Bundy. Jeffrey Dahmer. Charles Manson. Decades following their acts of violence, their names continue to incite fear as well as perplexity into the motivations that brought about their heinous crimes. As individuals possessing psychopathic personalities, they used their charm and quick wit to both manipulate and gain the trust of their victims. While their names do not elicit the same emotional response as Bundy or Manson, Bernie Madoff and Steve Jobs may also express the symptomology characteristic of psychopathy. But rather than committing violent crimes, they channeled their talents to the advancement of their careers and toward financial gain. …
Personality As A Moderator Of The Relationship Between Stress And Academic Deviance, Aaron Williams
Personality As A Moderator Of The Relationship Between Stress And Academic Deviance, Aaron Williams
Modern Psychological Studies
Academic deviance poses a continual threat to the education system from its persistence through generations and its presence in almost every form of institutionalized education (Davis et al., 1992). The aim of the present study was to integrate both situational and individual components of stress to examine their influence on academic deviance while testing the moderating role of trait impulsiveness on the degree of academic deviance displayed. Participants were 125 (98 women, 27 men) college students at a private university in the southern region of the United States. The Academic Dishonesty Inventory (Lucas, 2005) was used to measure academic deviance, …
The Right Not To Use In Property And Patent Law, Oskar Liivak, Eduardo M. Peñalver
The Right Not To Use In Property And Patent Law, Oskar Liivak, Eduardo M. Peñalver
Cornell Law Faculty Publications
In Continental Paper Bag Co. v. Eastern Paper Bag Co., the Supreme Court held (1) that patent owners have an absolute right not to practice their patent and (2) that even these nonpracticing patent owners are entitled to the liberal use of injunctive relief against infringers. Both of these holdings have been very important to the viability of patent assertion entities, the so-called patent trolls. In eBay Inc. v. MercExchange, L.L.C., the Supreme Court softened the injunction rule. In this Article, we argue that Congress or the Court should reconsider Continental Paper Bag’s embrace of an absolute right …
The Role Of Flow Sensing By The Lateral Line System In Prey Detection In Two African Cichlid Fishes, Margot Anita Bergstrom Schwalbe
The Role Of Flow Sensing By The Lateral Line System In Prey Detection In Two African Cichlid Fishes, Margot Anita Bergstrom Schwalbe
Open Access Dissertations
The mechanosensory lateral line system is found in all fishes and mediates critical behaviors, including prey detection. Widened canals, one of the four patterns of cranial lateral line canals found among teleosts, tend to be found in benthic fishes and/or fishes that live in hydrodynamically quiet or light-limited environments, such as the deep sea. Little is known about the functional significance of widened canals because most fishes with this morphology are inaccessible for laboratory study. A representative of one genus of Lake Malawi cichlid fishes, Aulonocara, has widened canals and provides an opportunity to investigate the role of widened …
Between Stonewall And Aids: Initial Efforts To Establish Gay And Lesbian Social Services, Michael G. Lee
Between Stonewall And Aids: Initial Efforts To Establish Gay And Lesbian Social Services, Michael G. Lee
The Journal of Sociology & Social Welfare
Little has been written about gay and lesbian communities' efforts to address health and human service concerns prior to the HIV/AIDS crisis. This article analyzes content from The Advocate along with organizational documents from the early 1970s to explore the health issues addressed by these fledgling providers. Major concerns identified include social adjustment to a gay or lesbian identity, chemical health, sexual health, and family supports. These findings depict a service context strained by funding instability, workplace turmoil, neighborhood hostility, and high levels of consumer needs that would later come to characterize the complex nature of AIDS service work.
Fear And Loathing: Shame, Shaming, And Intellectual Property, Elizabeth L. Rosenblatt
Fear And Loathing: Shame, Shaming, And Intellectual Property, Elizabeth L. Rosenblatt
DePaul Law Review
No abstract provided.
Fall 2013
Scientia
Exciting start to the year at CSH; Science program offers a college sneak peek for Southside youth; The math class you've been waiting for; Nursing Double Demon shares story of success; Lab notes; Accolades; Many Dreams, One Mission campaign for DePaul University
Large Scale Full-Length Cdna Sequencing Reveals A Unique Genomic Landscape In A Lepidopteran Model Insect, Bombyx Mori, Yoshitaka Suetsugu, Ryo Futahashi, Hiroyuki Kanamori, Keiko Kadono-Okuda, Shun-Ichi Sasanuma, Junko Narukawa, Masahiro Ajimura, Nobukazu Namiki, Michihiko Shimomura, Hideki Sezutsu, Mizuko Osanai-Futahashi, Masataka G. Suzuki, Takaaki Daimon, Tetsuro Shinoda, Kiyoko Taniai, Kiyoshi Asaoka, Ryusuke Niwa, Shinpei Kawaoka, Susumu Katsuma, Toshiki Tamura, Hiroaki Noda, Masahiro Kasahara, Sumio Sugano, Yutaka Suzuki, Haruhiko Fujiwara, Kallare P. Arunkumar, Archana Tomar, Javaregowda Nagaraju, Marian R. Goldsmith, Qili Feng, Qingyou Xia, Kimiko Yamamoto, Toru Shimada, Kazuei Mita
Large Scale Full-Length Cdna Sequencing Reveals A Unique Genomic Landscape In A Lepidopteran Model Insect, Bombyx Mori, Yoshitaka Suetsugu, Ryo Futahashi, Hiroyuki Kanamori, Keiko Kadono-Okuda, Shun-Ichi Sasanuma, Junko Narukawa, Masahiro Ajimura, Nobukazu Namiki, Michihiko Shimomura, Hideki Sezutsu, Mizuko Osanai-Futahashi, Masataka G. Suzuki, Takaaki Daimon, Tetsuro Shinoda, Kiyoko Taniai, Kiyoshi Asaoka, Ryusuke Niwa, Shinpei Kawaoka, Susumu Katsuma, Toshiki Tamura, Hiroaki Noda, Masahiro Kasahara, Sumio Sugano, Yutaka Suzuki, Haruhiko Fujiwara, Kallare P. Arunkumar, Archana Tomar, Javaregowda Nagaraju, Marian R. Goldsmith, Qili Feng, Qingyou Xia, Kimiko Yamamoto, Toru Shimada, Kazuei Mita
Biological Sciences Faculty Publications
The establishment of a complete genomic sequence of silkworm, the model species of Lepidoptera, laid a foundation for its functional genomics. A more complete annotation of the genome will benefit functional and comparative studies and accelerate extensive industrial applications for this insect. To realize these goals, we embarked upon a large-scale full-length cDNA collection from 21 full-length cDNA libraries derived from 14 tissues of the domesticated silkworm and performed full sequencing by primer walking for 11,104 full-length cDNAs. The large average intron size was 1904 bp, resulting from a high accumulation of transposons. Using gene models predicted by GLEAN and …
Functional Dna Methylation Differences Between Tissues, Cell Types, And Across Individuals Discovered Using The M&M Algorithm, Bo Zhang, Nan Lin, Rebecca F. Lowdon, Daofeng Lil, Michael Stevens, Hyung Joo Lee, Xiaoyun Xing, Jia Zhou, Vasavi Sundaram, Ginell Elliott, Junchen Gu, Pamela A.F. Madden, Ting Wang, Et Al
Functional Dna Methylation Differences Between Tissues, Cell Types, And Across Individuals Discovered Using The M&M Algorithm, Bo Zhang, Nan Lin, Rebecca F. Lowdon, Daofeng Lil, Michael Stevens, Hyung Joo Lee, Xiaoyun Xing, Jia Zhou, Vasavi Sundaram, Ginell Elliott, Junchen Gu, Pamela A.F. Madden, Ting Wang, Et Al
Open Access Publications
No abstract provided.
Bves And Ndrg4 Regulate Directional Epicardial Cell Migration Through Autocrine Extracellular Matrix Deposition, Emily C. Benesh, Paul M. Miller, Elise R. Pfaltzgraff, Nathan E. Grega-Larson, Hillary A. Hager, Bong Hwan Sung, Xianghu Qu, H. Scott Baldwin, Alissa M. Weaver, David M. Bader
Bves And Ndrg4 Regulate Directional Epicardial Cell Migration Through Autocrine Extracellular Matrix Deposition, Emily C. Benesh, Paul M. Miller, Elise R. Pfaltzgraff, Nathan E. Grega-Larson, Hillary A. Hager, Bong Hwan Sung, Xianghu Qu, H. Scott Baldwin, Alissa M. Weaver, David M. Bader
Open Access Publications
No abstract provided.
Histone Posttranslational Modifications And Cell Fate Determination: Lens Induction Requires The Lysine Acetyltransferases Cbp And P300, Louise Wolf, Wilbur Harrison, Jie Huang, Qing Xie, Ningna Xiao, Jian Sun, Lingkun Kong, Salil A. Lachke, Murali R. Kuracha, Venkatesh Govindarajan, Paul K. Brindle, Ruth Ashery-Padan, David C. Beebe, Paul A. Overbeek, Ales Cvekl
Histone Posttranslational Modifications And Cell Fate Determination: Lens Induction Requires The Lysine Acetyltransferases Cbp And P300, Louise Wolf, Wilbur Harrison, Jie Huang, Qing Xie, Ningna Xiao, Jian Sun, Lingkun Kong, Salil A. Lachke, Murali R. Kuracha, Venkatesh Govindarajan, Paul K. Brindle, Ruth Ashery-Padan, David C. Beebe, Paul A. Overbeek, Ales Cvekl
Open Access Publications
No abstract provided.
An Analysis Of Eliminating Electroosmotic Flow In A Microfluidic Pdms Chip, Cecile D. Redington
An Analysis Of Eliminating Electroosmotic Flow In A Microfluidic Pdms Chip, Cecile D. Redington
Master's Theses
The goal of this project is to eliminate electroosmotic flow (EOF) in a microfluidic chip. EOF is a naturally occurring phenomenon at the fluid-surface interface in microfluidic chips when an electric field is applied across the fluid. When isoelectric focusing (IEF) is carried out to separate proteins based on their surface charge, the analytes must remain in the separation chamber, and not migrate to adjacent features in the microfluidic chip, which happens with EOF.
For this project, a microfluidic chip was designed and commissioned to be photolithographically transferred onto a Si wafer. A PDMS component was then casted on the …
Draft Genome Sequence Of Xylella Fastidiosa Subsp. Multiplex Strain Griffin-1 From Quercus Rubra In Georgia, Jianchi Chen, Hong Huang, Chung-Jan Chang, Drake C. Stenger
Draft Genome Sequence Of Xylella Fastidiosa Subsp. Multiplex Strain Griffin-1 From Quercus Rubra In Georgia, Jianchi Chen, Hong Huang, Chung-Jan Chang, Drake C. Stenger
School of Information Faculty Publications
The draft genome sequence of Xylella fastidiosa subsp. multiplex strain Griffin-1, isolated from a red oak tree (Quercus rubra) in Georgia, is reported here. The bacterium has a genome size of 2,387,314 bp, with a G+C content of 51.7%. The Griffin-1 strain genome contains 2,903 predicted open reading frames and 50 RNA genes.
Getting To Evo-Devo: Concepts And Challenges For Students Learning Evolutionary Developmental Biology, Anna Hiatt, Gregory K. Davis, Caleb Trujillo, Mark Terry, Donald P. French, Rebecca M. Price, Kathryn E. Perez, Diane Ebert-May
Getting To Evo-Devo: Concepts And Challenges For Students Learning Evolutionary Developmental Biology, Anna Hiatt, Gregory K. Davis, Caleb Trujillo, Mark Terry, Donald P. French, Rebecca M. Price, Kathryn E. Perez, Diane Ebert-May
School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)
In this study we used surveys of evo-devo experts to identify the core concepts of evo-devo and outline an underlying conceptual framework. We also use interviews and surveys of conceptual difficulties with these concepts.
To examine how well biology majors have achieved the necessary foundation in evolution, numerous studies have examined how students learn natural selection. However, no studies to date have examined how students learn developmental aspects of evolution (evo-devo). Although evo-devo plays an increasing role in undergraduate biology curricula, we find that instruction often addresses development cursorily, with most of the treatment embedded within instruction on evolution. Based …
Practical And Theoretical Implications Of Digitizing The Middle Ages, Roberta Capelli
Practical And Theoretical Implications Of Digitizing The Middle Ages, Roberta Capelli
CLCWeb: Comparative Literature and Culture
In her article "Practical and Theoretical Implications of Digitalizing the Middle Ages" Roberta Capelli discusses scholarship about and the teaching of medieval culture in digital humanities. While every medieval manuscript is an individual entity, displaying a series of unique and unrepeatable material, structural and aesthetic characteristics, digital devices are able to generate only two-dimensional photographic reproductions. However, the digital medium brings about some major improvements in the study — and teaching — of medieval manuscripts because the hypertextual nature of its applications allows us to analyse simultaneously synchronic and the diachronic dynamics. From a theoretical point of view, the difference …