Digital Commons Network^™

Effect Of Hinge Region Phosphorylation On The Localization Of Thp1 In Tetrahymena Thermophila, Emily Bulley, Emily Wiley

Scripps Senior Theses

Within the cell nucleus, there are regions of highly condensed, transcriptionally silent chromatin called heterochromatin. Heterochromatin plays an important role in both chromosomal stability and gene regulation within the cell. Heterochromatin assembly is mediated by Heterochromatin Protein 1 (HP1) binding to epigenetically marked histone tails, most notably methylated H3K9. HP1 is post-translationally phosphorylated at serine and threonine residues, and this phosphorylation has been shown to increase HP1’s binding affinity for methylated H3K9 and heterochromatin formation. To study the effect of phosphorylation on heterochromatin assembly and HP1 localization within the nucleus, the unicellular protozoan Tetrahymena thermophila was used. Tetrahymena is an …

Motivation In Athletes With And Without Autism Spectrum Disorder: Sq, Eq And Aq Relationships To Preferred Feedback, Julia C. Harreschou

Scripps Senior Theses

All athletes are driven by motivation, sources or reasons to push their bodies to their limits and continue to do so regularly. There have been several studies concerning motivation in typical athletes, and many regarding social motivation in people with High Functioning Autism (HFA), however most have been limited to children, and there have been no investigations into HFA athletes’ motivation. The current study looks into the role of social dimensions in athletics, and tests how one’s gender and placement on the Empathy Questionnaire (EQ), Systemizing Questionnaire (SQ), and on the Autism Questionnaire (AQ) affect intrinsic motivation in athletics. It …

Nutritional Status Of Orphaned And Separated Children And Adolescents Living In Community And Institutional Environments In Uasin Gishu County, Kenya, Paula Braitstein, Samuel Ayaya, Winstone M. Nyandiko, Allan Kamanda, Julius Koech, Peter Gisore, Lukoye Atwoli, Rachel C. Vreeman, Corey Duefield, David O. Ayuku

Paediatrics and Child Health, East Africa

Objective: To describe the nutritional status of orphaned and separated children and adolescents (OSCA) living in households in the community (HH), on the street, and those in institutional environments in western Kenya. Methods: The study enrolled OSCA from 300 randomly selected households (HH), 19 Charitable Children’s Institutions(CCIs), and 100 street-involved children. Measures of malnutrition were standardized with Z-scores using World Health Organization criteria; Z-scores #-2 standard deviations (sd) were moderate-severe malnutrition. Data were analyzed using multivariable logistic regression adjusting for child age, sex, HIV status, whether the child had been hospitalized in theprevious year, time living with current guardian, and …

The Spillikin (Vol. 30), Valparaiso University

The Spillikin - The Christ College Newsletter

No abstract provided.

Predicting Groundwater Trading In The Upper Republican Natural Resource District, Elizabeth M. Juchems, Karina A. Schoengold

Cornhusker Economics

While surface water trading has occurred regularly throughout the Western United States and the rest of the world for decades, the use of any type of groundwater trading has been very limited. However, groundwater is increasingly under stress from overuse and many areas are starting to regulate groundwater use. While the public benefits from efficient use of groundwater include adequate stream flow in hydrologically connected areas and future availability of groundwater supplies, there are significant private benefits to landowners, especially in water short areas. Groundwater trading can help move water from low-value to high-value areas of use. Previous work on …

Bgsu Graduate College 2013-2014 Catalog, Bowling Green State University

Course Catalogs

Bowling Green State University graduate catalog for 2013-2014.

Impact Of Pre-Columbian Agriculture, Climate Change, And Tectonic Activity Inferred From A 5,700-Year Paleolimnological Record From Lake Nicaragua, Jennifer E. Slate, Thomas C. Johnson, Ted C. Moore

Biology Faculty Publications

Lake Nicaragua, the largest lake in Central America, is a promising site for paleolimnological study of past climate change, tectonic and volcanic activity, and pre-Columbian agriculture in the region. It is near the northern limit of the Intertropical Convergence Zone (ITCZ), which brings the rainy season to the tropics, so effects of decreasing precipitation due to southern migration of the ITCZ through the Holocene should be observable. Because fault zones and an active volcano lie within the lake, the long-term impact of tectonic and volcanic activity can also be examined. Finally, the fertile volcanic soils near the lake may have …

Ricean Over Gaussian Modelling In Magnitude Fmri Analysis—Added Complexity With Negligible Practical Benefits, Daniel W. Adrian, Ranjan Maitra, Daniel B. Rowe

Mathematics, Statistics and Computer Science Faculty Research and Publications

It is well known that Gaussian modelling of functional magnetic resonance imaging (fMRI) magnitude time-course data, which are truly Rice distributed, constitutes an approximation, especially at low signal-to-noise ratios (SNRs). Based on this fact, previous work has argued that Rice-based activation tests show superior performance over their Gaussian-based counterparts at low SNRs and should be preferred in spite of the attendant additional computational and estimation burden. Here, we revisit these past studies and, after identifying and removing their underlying limiting assumptions and approximations, provide a more comprehensive comparison. Our experimental evaluations using Receiver Operating Characteristic (ROC) curve methodology show that …

Recent Advances In Energy-Efficient Sensor Networks, Sheikh Iqbal Ahamed, Wei Wang, Jiman Hong

Mathematics, Statistics and Computer Science Faculty Research and Publications

No abstract provided.

Cross‐Campus Collaboration: A Scientometric And Network Case Study Of Publication Activity Across Two Campuses Of A Single Institution, Jeremy Birnholtz, Shion Guha, Y. Connie Yuan, Geri Gay, Caren Heller

Mathematics, Statistics and Computer Science Faculty Research and Publications

Team science and collaboration have become crucial to addressing key research questions confronting society. Institutions that are spread across multiple geographic locations face additional challenges. To better understand the nature of cross‐campus collaboration within a single institution and the effects of institutional efforts to spark collaboration, we conducted a case study of collaboration at Cornell University using scientometric and network analyses. Results suggest that cross‐campus collaboration is increasingly common, but is accounted for primarily by a relatively small number of departments and individual researchers. Specific researchers involved in many collaborative projects are identified, and their unique characteristics are described. Institutional …

Genome-Wide Associations Of Signaling Pathways In Glioblastoma Multiforme, Serdar Bozdag, Stefan Wuchty, Alexei Vazquez, Peter O. Bauer

Mathematics, Statistics and Computer Science Faculty Research and Publications

Background: eQTL analysis is a powerful method that allows the identification of causal genomic alterations, providing an explanation of expression changes of single genes. However, genes mediate their biological roles in groups rather than in isolation, prompting us to extend the concept of eQTLs to whole gene pathways. Methods: We combined matched genomic alteration and gene expression data of glioblastoma patients and determined associations between the expression of signaling pathways and genomic copy number alterations with a non-linear machine learning approach. Results: Expectedly, over-expressed pathways were largely associated to tag-loci on chromosomes with signature alterations. Surprisingly, tag-loci that were associated …

A Proposal For A Problem-Driven Mathematics Curriculum Framework, Judith S. Zawojewski, Marta Magiera, Richard Lesh

Mathematics, Statistics and Computer Science Faculty Research and Publications

A framework for a problem-driven mathematics curriculum is proposed, grounded in the assumption that students learn mathematics while engaged in complex problem-solving activity. The framework is envisioned as a dynamic technologicallydriven multi-dimensional representation that can highlight the nature of the curriculum (e.g., revealing the relationship among modeling, conceptual, and procedural knowledge), can be used for programmatic, classroom and individual assessment, and can be easily revised to reflect ongoing changes in disciplinary knowledge development and important applications of mathematics. The discussion prompts ideas and questions for future development of the envisioned software needed to enact such a framework.

Equity On The Extended Continental Shelf? How An Obscure Provision In Unclos Provides New Challenges For Ocean Governance, Aldo Chircop

Reports & Public Policy Documents

One of the major novelties of the United Nations Convention on the Law of the Sea, 1982 is the legitimizing of coastal State claims to large areas of continental margins in all oceans by virtue of Article 76. In addition to exclusive economic zones (EEZs) of 200 nautical miles, coastal States whose continental margins extend beyond the EEZ limit are able to further claim the seabed and subsoil beyond the EEZ limit to 350 nautical miles from the base lines of the territorial sea or 100 nautical miles from the 2,500 metre isobath. The UN Convention established a procedure for …

Influences Of Ecological Light Pollution On Advertisement Calls Of Spea Multiplicata (Amphibia: Anura: Scaphiopodidae) In Rural And Urban Populations In The Northern Chihuahuan Desert And An Evaluation Of Hybrid S. Bombifrons X S. Multiplicata Calls, Katie Anderson

Open Access Theses & Dissertations

Spea is a genus of toad-like, arid adapted frogs distributed throughout much of the western U.S. and northern Mexico. Two species, (S. Bombifrons and S. Multiplicata) are syntopic throughout most of the northern Chihuahuan Desert, a region that is experiencing rapid urbanization. For this study, I examined 936 male advertisement calls from urban and rural populations of S. multiplicata, and a rural population of S. bombifrons in west Texas and south-central New Mexico. Advertisement calls from urban and rural S. multiplicata were compared against light level to assess the potential influence ecological light pollution plays in sexual …

Interaction Of Ceo2 And Zno Nanoparticles Towards The Symbiotic Association Of Alfalfa (Medicago Sativa) And Sinorhizobium Meliloti In Soil, Susmita Bandyopadhyay

Open Access Theses & Dissertations

The production of engineered nanoparticles (ENPs) has rapidly increased due to their wide range of applications in the field of electronics, medicine, chemistry and biology. Consequently, concerns have risen about the environmental release and potential negative impact of NPs. A few reports have described the effects of TiO2 NPs and quantum dots upon nitrogen fixing bacteria. However, the understanding of the interaction of NPs in plant-microbe interface (symbiotic association), like alfalfa (Medicago sativa L.)-Sinorhizobium meliloti, is still in its infancy. Alfalfa is the world's most important forage crop. It grows in association with S. meliloti, which is very important in …

Expression And Characterization Of The Major Capsid Protein (Mcp) Of A Giant Marine Virus: Cafeteria Roenbergensis Virus, Sayan Chakraborty

Open Access Theses & Dissertations

The oceans play significant roles in maintaining the climate on Earth and providing nutrients to the whole biosphere. Oceanic microbes produce approximately half of the Earth's oxygen. It has been shown that the populations of microbial communities in oceans are largely regulated by viral infection and thus affect the marine ecosystem. Cafeteria roenbergensis Virus (CroV) is a giant marine virus with a linear, double stranded, and AT-rich DNA genome. The genome of CroV has a size of 744kb and encodes for 544 predicted genes. CroV derived its name from its host, a unicellular marine zooplankton Cafeteria roenbergensis (Cro) that is …

Post-Pareto Optimality Methods For The Analysis Of Large Pareto Sets In Multi-Objective Optimization, Victor Manuel Carrillo

Open Access Theses & Dissertations

Multiple objective optimization involves the simultaneous optimization of more than one, possibly conflicting, objectives. Multiple objective optimization problems arise in a variety of real-world applications. In general, the main difference between single and multi-objective optimization is that in multi-objective optimization there is usually no single optimal solution, but a set of equally good alternatives with different trade-offs, also known as Pareto-optimal solutions. There are two general approaches to solve multiple objective optimization problems: mathematical methods and meta-heuristic methods. The first approach involves the aggregation of the attributes into a linear combination of the objective functions, also known as scalarization. The …

Low Birth Weight, Prenatal Smoking, Pest Exposure And Breastfeeding Modify The Effect Of Acculturation On Hispanic Children's Asthma, Paola Chavez Payan

Open Access Theses & Dissertations

Prior research suggests that Hispanic migrants in the U.S. experience better respiratory health than their U.S.-born counterparts; this is reflective of a Hispanic health paradox (HHP). I address the following research questions with a focus on the HHP among children in the urban US border setting of El Paso, Texas: 1) Does acculturation relate to current asthma symptoms and diagnosed asthma? 2) Does the relationship between acculturation and current asthma symptoms and diagnosed asthma persist when controlling for relevant risk factors? 3) How does acculturation modify the relationships between the risk factors and current asthma symptoms and diagnosed asthma? Data …

Development Of A New Genetic Algorithm To Solve The Feedstock Scheduling Problem In An Anaerobic Digester, Ana Cram

Open Access Theses & Dissertations

Genetic Algorithm

Scheduling

Anaerobic digester

Stress Appraisal, Coping Response, And Acculturation Level As Predictors Of Postpartum Depression Symptoms In Women Of Mexican Origin, Rena M. Digregorio

Open Access Theses & Dissertations

Transition into motherhood may be a time of mixed emotion. Though most women embrace motherhood and are optimistic about the role, approximately 13% of all women who give birth suffer from postpartum depression (Beck, C.T., 2001; Beck, C.T., 1996; O'Hara & Swain, 1996). However, some studies report women of Mexican origin suffer postpartum depressive symptoms at much higher rates than other racial and ethnic groups (Diaz, Huynh-Nhu, Cooper, & Munoz, 2007). Understanding how and to what extent postpartum depressive symptoms affect mothers of Mexican origin remains incomplete. This 10 month prospective, repeated measures, proxy pretest study of pregnant and postpartum …

Lead And Associated Heavy Metal Distribution In El Paso, Texas, Ali Ragab Elkekli

Open Access Theses & Dissertations

Contamination by lead and other heavy metals is one of the most important environmental concerns of today, locally and globally. This issue has led scientists and researchers to study the effect of heavy metals and their distribution in the environment. The aim of the present research is to document the concentration and geographic distribution of heavy metals in El Paso.

The selected heavy metals in the El Paso soil are lead, cadmium, chromium, zinc, antimony and copper. The soil sample for the study was collected during a previous community lead study (RO1 ESO11367; 2001-2006). 500 superficial soils samples were collected …

The Association Of Vitamin D Status With Allergy And Asthma In Children: Findings From The National Health And Nutrition Examination Survey (Nhanes) 2005-2006, Silvia Flores

Open Access Theses & Dissertations

About 23 million people, including almost 10 million children, have asthma in the United States. Asthma prevalence is higher among families with lower incomes living at the US/ Mexico Border and represents the most common serious chronic diseases of childhood. It is the third-ranking cause of hospitalization among children under 15, (De Frances, 2007) as well as the cause of seven million physician visits and nearly 200,000 hospitalizations every year. An average of one out of every ten school-aged children has asthma and, 13 million school days are missed each year due to asthma symptoms (Akinbami, 2006). According to the …

Urban Impact Of Dissolved Metals In The Paso Del Norte Segment Of The Rio Grande, Sumayeh Ahmad Freiwan

Open Access Theses & Dissertations

The Paso del Norte segment of the Rio Grande experiences two seasons per year; the (wet) irrigation season and the (dry) non-irrigation season. The goal of this study was to improve the understanding of occurrence and contribution of dissolved metals in this region during the non-irrigation season. The objectives of this study were to (1) evaluate the impact of anthropogenic sources of metals on the Rio Grande water quality during the non-irrigation season, and (2) estimate the metal loads carried by the flow to the downstream region of El Paso. In order to evaluate the surface water quality of the …

A Semantic Web-Based Methodology For Describing Scientific Research Efforts, Aida Gandara

Open Access Theses & Dissertations

Scientists produce research resources that are useful to future research and innovative efforts. In a typical scientific scenario, the results created by a collaborative team often include numerous artifacts, observations and relationships relevant to research findings, such as programs that generate data, parameters that impact outputs, workflows that describe processes, and publications, posters and presentations that explain results and findings. Scientists have options in what results to share and how to share them, however, there is no systematic approach to documenting scientific research and sharing it on the Web.

The goal of this research is to define a systematic approach …

Optimization Of Bioprinting Process Using Design Of Experiments (Doe) And Taguchi Method, Maria Veronica Gonzalez

Open Access Theses & Dissertations

At this time there is a need for new fabrication techniques for engineering complex biological structures related to regenerative medicine, in vitro tissue analysis, and pharmaceutical testing with the purpose of placing specific cells in specific target locations. Right now, there is no enough conventional cell seeding methods that can achieve it. In order to achieve it, bio-fabrication, which is a delivery mechanism capable of placing biomaterials, cells, and bioactive macromolecules in specific target locations, comes to play an important role in this area. Among different approaches, bioprinting is one of the most useful processes that use drop-on-demand delivery mechanisms …

Lead And Associated Heavy Metal Distribution In Ciudad Juarez, Mexico, Samia Elfituri Grimida

Open Access Theses & Dissertations

Concern over the extent and sources of heavy metals exposure has arisen worldwide since their significant effects have been discovered in the environment. There is general agreement that research is needed to examine the residual lead and its association to heavy metals contamination in soil and quantify the health hazards. This research was directed to quantify and document the geographic distribution of lead and associated heavy metals concentration in Ciudad Juarez, Mexico. Lead, cadmium, chromium, zinc, and copper were selected to analysis. The soil samples used in this research were collected during a previous Encountors Binational Community Lead Study (RO1ES …

Development Of `Lick And Stick' Passive Wireless Temperature Sensor For Harsh Environment, Hasanul Karim

Open Access Theses & Dissertations

Wireless passive temperature sensors have been receiving increasing attention due to the ever-growing need of higher energy efficient and precise monitoring of temperatures in high temperature energy conversion systems such as gas turbines and coal-based power plants. Unfortunately, the harsh environment such as high temperature and corrosive atmosphere present in these systems has significantly limited the reliability and increased the cost of current solutions. Therefore, this research project presents the concept and design of a low cost, passive, and wireless temperature sensor that can withstand high temperature and harsh environment. The temperature sensor was designed following the principle of metamaterials …

Toward New Data And Information Management Solutions For Data-Intensive Ecological Research, Christine Marie Laney

Open Access Theses & Dissertations

Ecosystem health is deteriorating in many parts of the world due to direct and indirect anthropogenic pressures. Generating accurate, useful, and impactful models of past, current, and future states of ecosystem structure and function is a complex endeavor that often requires vast amounts of data from multiple sources and knowledge from collaborating researchers. Ecological data collection has improved rapidly over the past few decades due to the development, innovation, and large scale deployment of automated sensors, which are capable of measuring a gamut of ecosystem properties over broad spatiotemporal scales. Although complex ecosystem models and analyses are increasingly parameterized with …

A Revision Of The New World Ants Of The Genus Platythyrea Roger 1863 (Hymenoptera: Formicidae), Mayra Janett Leyva

Open Access Theses & Dissertations

The genus Platythyrea consists of arboreal ants that are rarely collected. The genus was last partially revised in 1975 by Brown. Since that revision two additional species have been described. The New World genus Platythyrea now includes nine species: P. angusta Forel, P. exigua Kempf, P. lenca De Andrade, P. pilosula (Smith), P. prizo Kugler, P. punctata (Smith), P. sinuata (Roger), P. strenua Wheeler and P. zodion Brown. A new key, illustrations, diagnoses and distributions of the ants are provided.

Method Development For A Chemical And Biological Analysis Of Glucocorticoids In Wastewater, Maria Carmen Lozano

Open Access Theses & Dissertations

Glucocorticoids are a class of steroid hormones that can either be produced synthetically or naturally by the adrenal glands. The synthetic glucocorticoids are highly prescribed in the United States for their anti-inflammatory and immunosuppressive properties to treat a variety of ailments and diseases; however, these have been implicated in a number of adverse human conditions such as obesity, metabolic syndrome, immune-suppression, delayed puberty, adrenal insufficiency and Cushing Syndrome, among others. Ongoing research has shown that synthetic and natural hormones are transported to aquatic environments via mammalian excretion or wastewater effluent, and as a result, the release of glucocorticoids into the …