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2013

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Probe Immobilization Strategies And Device Optimization For Novel Transistor-Based Dna Sensors, Nicholas Michael Fahrenkopf Jan 2013

Probe Immobilization Strategies And Device Optimization For Novel Transistor-Based Dna Sensors, Nicholas Michael Fahrenkopf

Legacy Theses & Dissertations (2009 - 2024)

The research presented herein exploits the terminal phosphate group on single stranded DNA molecules for direct immobilization to surfaces utilized in semiconductor device fabrication with the end goal of transistor based DNA sensors. As a demonstration of the feasibility of this immobilization strategy DNA immobilization to a variety of surfaces was evaluated for usefulness in biosensor applications. It was determined that DNA can be directly immobilized to a variety of semiconductor surfaces through the terminal phosphate group. Further, this immobilization allows for the hybridization of the immobilized DNA to complementary target in solution. The immobilization of DNA to hafnium dioxide …

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Making Sense Of Mason Jars : A Qualitative Exploration Of Contemporary Home Canning, P. Suzanne Pennington Jan 2013

Making Sense Of Mason Jars : A Qualitative Exploration Of Contemporary Home Canning, P. Suzanne Pennington

Legacy Theses & Dissertations (2009 - 2024)

The practice and popularity of home canning in the United States has dramatically fluctuated since John Mason’s 1858 invention of the ‘fruit’ jar, influenced by cultural trends and sociopolitical events such as war, economic oscillation, activist movements such as environmentalism, and the politicization of food. The contemporary social context in which popular interest in home canning has most recently revived is an era of high cultural awareness and activity regarding multiple food issues. Traditional American foodways, including food preservation techniques such as home canning, are regaining importance as many Americans look to the past for solutions to current needs. This …

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Conditioned Arousal To Slot Machine Wins : An Examination Of Renewal Following Extinction, James Broussard Jan 2013

Conditioned Arousal To Slot Machine Wins : An Examination Of Renewal Following Extinction, James Broussard

Legacy Theses & Dissertations (2009 - 2024)

The objective of this study was to explore whether an appetitive response extinguished in one context would remain extinguished when tested in the extinction context, but show renewal when tested in a different context. Forty college students played a slot machine while their physiological arousal (skin conductance and heart rate) and desire to play were being recorded. During the acquisition phase, wins on the slot machine were associated with a tone serving as a conditioned stimulus (CS) that preceded the machine's payout (US) and elicited conditioned arousal. During the following extinction phase, the CS was presented repeatedly without the US …

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The Family And Its Effects On Intergenerational Educational Attainment In The Bahamas, Marcellus C. Taylor Jan 2013

The Family And Its Effects On Intergenerational Educational Attainment In The Bahamas, Marcellus C. Taylor

Legacy Theses & Dissertations (2009 - 2024)

This exploratory study examines the individual and family effects on intergenerational educational attainment mobility giving focus to the Commonwealth of The Bahamas, a small, newly-independent nation in the Caribbean region.

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H.D. And Freedom : Realization Through Nature, Vision, And Gender Authority, Jared Young Jan 2013

H.D. And Freedom : Realization Through Nature, Vision, And Gender Authority, Jared Young

Legacy Theses & Dissertations (2009 - 2024)

This thesis is a study in the constructs of H.D.'s poetry, and how they work in relation to the reader. Specifically, H.D.'s concern was creating a sense of freedom for her readers as a means to representation and identity. To achieve this state of consciousness, H.D. began by exploring the sacredness within nature. In the process of articulating her idea into a more exact form she turned her focus towards gender. By removing the objective aesthetics surrounding women, H.D. developed a gender authority. Through this authority she continued her quest for freedom and, in doing so, instilled a sense of …

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The Localized Manipulation Of The Extracellular Matrix Within 3d Collagen Cell Cultures Using A Biomems Device, Ashley N. Clark Jan 2013

The Localized Manipulation Of The Extracellular Matrix Within 3d Collagen Cell Cultures Using A Biomems Device, Ashley N. Clark

Legacy Theses & Dissertations (2009 - 2024)

Approximately 90% of all cancer related deaths can be attributed to the occurrence of metastasis. There are multiple changes that occur within the tumor microenvironment that have been correlated with the onset of metastasis. Different cell types, extracellular matrices, blood vessels, and soluble factors are some of the various components that make up the complex, heterogeneous microenvironment that exists within a tumor. The dynamic relationship between tumor cells and their surrounding environment makes it an ideal environment to study triggers of metastasis, such as the modification of the extracellular matrix. Changes in the multiple aspects of extracellular matrix composition have …

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Raman Spectroscopy For The Identification Of Body Fluid Traces : Mixtures And Contaminations, Race And Gender Differentation, Aliaksandra Sikirzhytskaya Jan 2013

Raman Spectroscopy For The Identification Of Body Fluid Traces : Mixtures And Contaminations, Race And Gender Differentation, Aliaksandra Sikirzhytskaya

Legacy Theses & Dissertations (2009 - 2024)

Body fluid traces are an important type of forensic evidence, which play a significant role in the reconstruction of a violent crime and often help to identify a victim or suspect based on DNA analysis. Despite a great need, there is no a single method, which could identify multiple body fluids. In addition, majority of current methods are destructive for the evidence. For about eight years, our laboratory has been working on the development of a new nondestructive method for identification of body fluid traces based on Raman microspectroscopy combined with advanced statistics. High differentiation power of the method has …

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The Sxrna Platform : Biophysical Characterization Of Trans-Acting Rna Switches For Gene Expression Control, Christine Bazinet Jan 2013

The Sxrna Platform : Biophysical Characterization Of Trans-Acting Rna Switches For Gene Expression Control, Christine Bazinet

Legacy Theses & Dissertations (2009 - 2024)

In the past decade, microRNAs (miRNAs) have become a hot topic in biochemical research. These very short ~ 22 nucleotide strands of RNA have been recognized as a functional RNA group and found to play a key role in mediating gene regulation along with RNA-binding proteins (RBPs). For example, by binding to the histone stem-loop (HSL) region of the target mRNA, normally in the 3'- untranslated region (UTR), gene expression can either be activated or deactivated for up or down regulation of the gene product. The majority of miRNAs have been found to down regulate gene expression upon binding to …

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Is Translation Enough? : A Study Of The Item Characteristics Which Influence Equivalence Between English And Spanish Versions Of A Selection Test, Andrea Valentine Jan 2013

Is Translation Enough? : A Study Of The Item Characteristics Which Influence Equivalence Between English And Spanish Versions Of A Selection Test, Andrea Valentine

Legacy Theses & Dissertations (2009 - 2024)

The goal of this study was to investigate the equivalence between an English and Spanish version of a selection test that was used to hire entry-level employees for a nationwide retail organization. By using a test that was back translated from English to Spanish, this study aimed at understanding whether different item characteristics are related to differential item functioning (DIF) and whether these item characteristics moderate the degree of equivalence between IRT item parameters. An understanding of which item characteristics influence equivalence can help guide researchers and practitioners in deciding on which items require test adaptation and which can simply …

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Using Administrative Data To Estimate The Burden Of Chlamydia Among Medicaid Managed Care Enrollees In New York State, Lindsay W. Cogan Jan 2013

Using Administrative Data To Estimate The Burden Of Chlamydia Among Medicaid Managed Care Enrollees In New York State, Lindsay W. Cogan

Legacy Theses & Dissertations (2009 - 2024)

Infection with Chlamydia trachomatis is of public health concern because of its adverse effects on reproduction. Women infected with Chlamydia can develop pelvic inflammatory disease, which can lead to serious reproductive system morbidity including ectopic pregnancy and infertility.

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White Noise : Negotiating Boundaries And Constructing Whiteness In Hip-Hop America, Carolyn Corrado Jan 2013

White Noise : Negotiating Boundaries And Constructing Whiteness In Hip-Hop America, Carolyn Corrado

Legacy Theses & Dissertations (2009 - 2024)

This dissertation examines the ways in which white hip-hop youth negotiate racial boundaries in their daily lives, and how this process of racial boundary negotiation in turn influences their construction of white racial identities. By focusing on white youth who mark their racial identity to varying degrees based on their level of involvement in hip-hop culture, and comparing and contrasting white hip-hop kids from a suburban area who live their lives in a homogenous, mostly white racial context to their counterparts from an urban area who live their lives in a heterogeneous, multiracial context, I have been able to parse …

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Functional Roles Of The Insulin-Regulated Glucose Transporter-4 In The Hippocampus, Jiah Pearson-Leary Jan 2013

Functional Roles Of The Insulin-Regulated Glucose Transporter-4 In The Hippocampus, Jiah Pearson-Leary

Legacy Theses & Dissertations (2009 - 2024)

Although a great deal of research has elucidated both localization and function of many glucose transporters (GluTs) throughout the brain, the function of brain insulin-responsive glucose transporter-4 (GluT4) remains unclear (McEwen & Reagan, 2004). Because type 2 diabetes mellitus (T2DM; insulin resistance, i.e., impaired insulin signaling) is a risk factor for Alzheimer's disease (AD), and because the signaling mechanisms insulin uses to mediate hippocampal processes and memory are unclear, a major purpose of this dissertation was to determine whether hippocampal GluT4, which is responsible for insulin's glucoregulatory and canonical effects in the periphery, is necessary for insulin's effects in the …

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Population Genetics And Ecology Of Regional Malaria Vectors In Amazonian Brazil, Sascha Naomi Mckeon Jan 2013

Population Genetics And Ecology Of Regional Malaria Vectors In Amazonian Brazil, Sascha Naomi Mckeon

Legacy Theses & Dissertations (2009 - 2024)

Species complexes are common among anopheline mosquitoes, but only some members of complexes are disease vectors. Research involving overall patterns of divergence, phylogenetic relationships and population structure is partly driven by the operational need to be able to reliably distinguish component taxa that may be involved in malaria transmission. Anopheles triannulatus, An. nuneztovari and An. albitarsis are broadly distributed species complexes that contain local and regionally important malaria vectors, whose genetic diversity has been largely overshadowed by studies involving An. darlingi, the principal vector of Central and South America. I have analyzed the ecological suitability of habitats and geographical ranges …

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Does Intimate Partner Violence Affect The Acceptability Of Expedited Partner Therapy?, Suzanne Elizabeth Beck Jan 2013

Does Intimate Partner Violence Affect The Acceptability Of Expedited Partner Therapy?, Suzanne Elizabeth Beck

Legacy Theses & Dissertations (2009 - 2024)

Background: Studies have identified associations between intimate partner violence (IPV) and elevated risk of sexually transmitted infections (STI). An estimated 6% of women in the United States have experienced physical and/or sexual assault inflicted by an intimate partner in the previous year. Of those with an STI, chlamydia is disproportionately reported for women. In 2009, New York State legalized Expedited Partner Therapy (EPT) for chlamydial infections; however clinicians are lacking guidance with respect to appropriate use of EPT when IPV is a concern.

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Impact Of Gender Inequality And Religion On How States Experience Terrorism, Aneela Salman Jan 2013

Impact Of Gender Inequality And Religion On How States Experience Terrorism, Aneela Salman

Legacy Theses & Dissertations (2009 - 2024)

This dissertation includes three essays that present a quantitative analysis of the policy implications of gender equality and religious attitudes as predictors of terrorism at the state level using a broad dataset. Essay one focuses on impact of gender equality, especially women's political empowerment on terrorism, both domestic and transnational. The second essay examines both gender equality attitudes and actual outcomes in social, economic and political spheres, to measure their effect on terrorism. The third essay analyzes the relation of religiousness in a society with incidents and lethality of terrorism. The overall findings of this thesis suggest that attitudes and …

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Feeling Knowledge : How Emotion And Identity Inform Student Learning, Rebecca M. Ossorio Jan 2013

Feeling Knowledge : How Emotion And Identity Inform Student Learning, Rebecca M. Ossorio

Legacy Theses & Dissertations (2009 - 2024)

The exploratory and descriptive purpose of this work is to better understand what might be happening when students have an emotional response to learning in school and to offer a way of conceptualizing emotion, identity and student learning as deeply interrelated. The data for this study comes from four in-depth, phenomenological interviews where contemplative educators were asked to recollect emotional experiences from their formal education and tell the story of how those experiences impacted their learning. Evidence suggests that when students have an emotional response to learning it is like a beacon alerting them to the self-relevance of what they …

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Acculturation, Family Dynamics And Psychological Well-Being Among Asian And Hispanic Adolescents In Immigrant Families : A Comparative Analysis, Yong Li Jan 2013

Acculturation, Family Dynamics And Psychological Well-Being Among Asian And Hispanic Adolescents In Immigrant Families : A Comparative Analysis, Yong Li

Legacy Theses & Dissertations (2009 - 2024)

Past research has consistently supported the view that adolescents in both Asian and Hispanic immigrant families may experience mental health problems such as depression and low self-esteem. The mechanisms influencing psychological well-being (PWB) may be conditioned by unique aspects of Asian and Hispanic culture. Based on the ecological systems framework, family systems theories, acculturation theories, and relevant literature, factors such as family dynamics, acculturation and their interactions may be important in shaping adolescent PWB. Examining these factors from a comparative perspective, between Asian and Hispanic adolescents, could provide new insights into the ways culturally responsive and competent services are planned …

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Cultural Control And Agency : A Quantitative Analysis Of Mazama Sp. And Odocoileus Sp. Osteological Remains From MayapáN, Yucatan, Mexico, Vivian S. James Jan 2013

Cultural Control And Agency : A Quantitative Analysis Of Mazama Sp. And Odocoileus Sp. Osteological Remains From MayapáN, Yucatan, Mexico, Vivian S. James

Legacy Theses & Dissertations (2009 - 2024)

Mayan management of deer populations at Mayapán in the Yucatán, México has been suggested by historical texts, iconography, and archaeological investigation. Therefore, the main research question of this thesis is: Was deer management or husbandry practiced at Mayapán? Two Cervidae species are identified in the Mayapán faunal assemblage, Odocoileus virginianus (white-tailed deer) and Mazama americana (brocket deer). It is likely that Mazama pandora (Yucatan brocket deer) is also present and possibly another Odocoileus subspecies. Consequently, the second research question of this thesis is: How many deer species or subspecies were present in Postclassic Period Mayapán? There is a considerable non-overlapping …

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The Songs Of Science : Rilke, Orpheus, And The Poetic Transformation Of The Natural Scientist, Evan Michael Gromel Jan 2013

The Songs Of Science : Rilke, Orpheus, And The Poetic Transformation Of The Natural Scientist, Evan Michael Gromel

Legacy Theses & Dissertations (2009 - 2024)

This thesis will attempt to illustrate a connection between both the creative and trying experiences of certain natural scientists surrounding their discoveries and Rilke's vision of poetry. It will explore the implications of Rilke's figure of Orpheus, which has been characterized in part as a symbol for art's "search in which something essential is at stake" (Blanchot 215), on the poetic potential of those whose perception is grounded in the psychology of modern scientific discovery and theory; In other words, how a scientist comes to make the turn which takes them from "the work" to "the work of art".

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Function And Regulation Of Intestinal P450 Enzymes : Insights From Conditional Cytochrome P450 Reductase Knockout Mouse Models, Yi Zhu Jan 2013

Function And Regulation Of Intestinal P450 Enzymes : Insights From Conditional Cytochrome P450 Reductase Knockout Mouse Models, Yi Zhu

Legacy Theses & Dissertations (2009 - 2024)

The overall goal of this thesis work was to investigate the function and regulation of intestinal P450 enzymes (P450s). The central hypotheses are that 1) small intestinal (SI) P450s play an important role in the first-pass clearance of oral drugs and in bioactivation of chemicals that cause intestinal toxicity, 2) endogenous regulatory compounds produced by intestinal P450s are important for protection against chemical-induced colon inflammation, and 3) there is a cross talk between the liver and the SI that helps to maintain the overall xenobiotic-metabolism capacity of the digestive tract.

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Second Generation Indo-Guyanese Adolescent Identity, Caitlin Irene Janiszewski Jan 2013

Second Generation Indo-Guyanese Adolescent Identity, Caitlin Irene Janiszewski

Legacy Theses & Dissertations (2009 - 2024)

This thesis investigates the lives of second generation Indo-Guyanese immigrants in Schenectady, New York. Through the creative means of playwriting, I demonstrate how these subjects saw identified racially, ethnically, nationally, and how gender is implicated in these identifications. I argue that the force of "colorblind" discourse and multicultural language in the context the United States promotes an ambiguous sense of racial, ethnic, and national identification. I argue that a Foucauldian framework which I call the "deployment of race" is what manages this ambiguity and disciplines subjects to use a "colorblind" grammar. This thesis/project also makes a methodological argument. The stage …

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Literature Of Exhaustion : The Comic, Decolonial Politics And Healing In Pedro Pietri's Puerto Rican Obituary, Tito Núñez Jan 2013

Literature Of Exhaustion : The Comic, Decolonial Politics And Healing In Pedro Pietri's Puerto Rican Obituary, Tito Núñez

Legacy Theses & Dissertations (2009 - 2024)

Abstract

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Outcome Expectancies Mediate The Impact Of Olfactory Cues On Marijuana Craving, Mallory Loflin Jan 2013

Outcome Expectancies Mediate The Impact Of Olfactory Cues On Marijuana Craving, Mallory Loflin

Legacy Theses & Dissertations (2009 - 2024)

Current work suggests that the presence of "craving" may be a significant indicator of problematic substance use. Nevertheless, little work has examined how cannabis users experience and develop craving. Most relevant studies focus on samples in treatment. Previous work suggests that cues for marijuana might activate outcome expectancies that contribute to the development of craving. The present study sought to test whether an olfactory marijuana cue would create changes in expectancy, mood, and craving in a non-treatment seeking sample representing both users and non-users. Unlike control cues, olfactory cues for marijuana increased perceptions of the likelihood of marijuana-induced positive outcomes …

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Study Of Key Factors Influencing Dust Emission : An Assessment Of Geos-Chem And Dead Simulations With Observations, Kevin Scott Bartlett Jan 2013

Study Of Key Factors Influencing Dust Emission : An Assessment Of Geos-Chem And Dead Simulations With Observations, Kevin Scott Bartlett

Legacy Theses & Dissertations (2009 - 2024)

Mineral dust aerosols can impact air quality, climate change, biological cycles, tropical cyclone development and flight operations due to reduced visibility. Dust emissions are primarily limited to the extensive arid regions of the world, yet can negatively impact local to global scales, and are extremely complex to model accurately. Within this dissertation, the Dust Entrainment And Deposition (DEAD) model was adapted to run, for the first known time, using high temporal (hourly) and spatial (0.3°x0.3°) resolution data to methodically interrogate the key parameters and factors influencing global dust emissions. The dependence of dust emissions on key parameters under various conditions …

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A Multiple Case Study Exploring The Intervention Processes Influencing Success For Dd/Mi Dually Diagnosed Adolescents, Julanne Colvin Jan 2013

A Multiple Case Study Exploring The Intervention Processes Influencing Success For Dd/Mi Dually Diagnosed Adolescents, Julanne Colvin

Legacy Theses & Dissertations (2009 - 2024)

Given what has been described in the literature about the life circumstances of youth who are dually diagnosed with a developmental disability and a mental or behavior disorder, we know that in the trajectory of their lives they are likely to live out of their homes and communities for lengthy periods of time in order to receive specialized treatment. The Intervention and Supports for Adolescents and Families (ISAF) program, an integrated multi-disciplinary treatment approach, was designed to cross over multiple service systems to address the challenges of delivering services to dually diagnosed youth and their families and reduce the risk …

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Vibrational Spectroscopic Analysis Of Gunshot Residue : A Novel Approach For Detection And Characterization, Justin J. Bueno Jan 2013

Vibrational Spectroscopic Analysis Of Gunshot Residue : A Novel Approach For Detection And Characterization, Justin J. Bueno

Legacy Theses & Dissertations (2009 - 2024)

Due to the increasing prevalence of firearm related crimes, there is a need for an all-encompassing analytical technique which can rapidly detect and analyze trace crime scene firearm evidence. There are several forms of ballistics and trace evidence associated with firearm offenses. Historically, the most neglected piece of evidence has ironically been the most prevalent. Each firearm discharge produces a so called gunshot residue (GSR) sample, expelling dust and particles numbering from hundreds to thousands throughout the shooting environment. The detection of GSR at a crime scene or on a suspect is critical for determining what actually happened during a …

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A Multilevel Investigation Of The Influence Of Family And School Level Factors On Age Of Sexual Initiation : A Focus On Sex Differences, Candace White Jan 2013

A Multilevel Investigation Of The Influence Of Family And School Level Factors On Age Of Sexual Initiation : A Focus On Sex Differences, Candace White

Legacy Theses & Dissertations (2009 - 2024)

Background and Purpose: Early sexual initiation is associated with unwanted pregnancy, depression, and other health risks, yet sexual intercourse is occurring at earlier ages than in past decades and teen pregnancy rates in the U.S are the highest in the

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An Implementation Study Of The Science And Technology Entry Program (Step) In New York State, Susan C. Perkins Jan 2013

An Implementation Study Of The Science And Technology Entry Program (Step) In New York State, Susan C. Perkins

Legacy Theses & Dissertations (2009 - 2024)

As global demands for workers in the science, technology, engineering and math (STEM) fields persist, there are increased opportunities for historically underrepresented African-American and Latino youth to fill STEM career pipelines. African-American and Latino youth have long faced disproportionately high unemployment rates. Joblessness has been complicated by lower high school graduation rates for African-American and Latino youth. Significant federal and state funding has been allocated to address this state of affairs. Research findings on STEM career development programs for historically underrepresented youth can inform public policy and resource allocation.

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Developmental Adaptation Hypothesis : Aerobic Capacity, Submaximal Arterial Saturation And Pulmonary Volumes In Peruvian Quechua Natives, Melisa Kiyamu Tsuchiya Jan 2013

Developmental Adaptation Hypothesis : Aerobic Capacity, Submaximal Arterial Saturation And Pulmonary Volumes In Peruvian Quechua Natives, Melisa Kiyamu Tsuchiya

Legacy Theses & Dissertations (2009 - 2024)

The Quechua populations have inhabited the Andes for hundreds of generations. The ability to thrive in this hostile environment, leading an active and healthy life has generated research questions about the special phenotype of Andean highlanders compared to their sea-level counterparts, such as their higher pulmonary volumes and their outstanding work capacity in spite of the challenge of oxygen transport and delivery in hypoxia. In high altitude natives, there have been two main explanations for the origins of the aforementioned traits: genetic adaptation through natural selection and developmental adaptation through the exposure to hypoxia during growth.

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The Anti-Abortion Legislation In Nicaragua : Gender Hierarchies And Ideologies In Reproduction, Ilona M. Flores Jan 2013

The Anti-Abortion Legislation In Nicaragua : Gender Hierarchies And Ideologies In Reproduction, Ilona M. Flores

Legacy Theses & Dissertations (2009 - 2024)

This research examines the anti-abortion legislation that was passed in Nicaragua in 2006. The methods of investigation involve participant/observation and collaboration, semi-structured interviews, and content analysis. Through examination of the legal and medical implications of criminalizing therapeutic abortions, this research demonstrates that the anti-abortion law attempts to enforce traditional gender roles. The abortion debate inspired many questions of morality and motherhood, and that access to therapeutic abortions meant denying `normal' gender roles. While some women internalized these notions, others did not. However, Nicaraguans use the conceptual framework of `salir adelante' as a way to practice agency.

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