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2013

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Efficacy Of Ozonation On Micro-Organisms Disinfection In Well Water Treatment, N.M. Norhayati, S.L. Yap, C.S.J. Teh, Kwai Lin Thong Jan 2013

Efficacy Of Ozonation On Micro-Organisms Disinfection In Well Water Treatment, N.M. Norhayati, S.L. Yap, C.S.J. Teh, Kwai Lin Thong

Research Publications (2011 to 2015)

No abstract provided.

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Enzymatic Characterization Of Insecticide Resistance Mechanisms In Field Populations Of Malaysian Culex Quinquefasciatus Say (Diptera: Culicidae), Van Lun Low, Chee Dhang Chen, Han Lim Lee, Tiong Kai Tan, Chin Fong Chen, Cherng Shii Leong, Yvonne Ai Lian Lim, Phaik Eem Lim, Yusoff Norma-Rashid, Mohd Sofian-Azirun Jan 2013

Enzymatic Characterization Of Insecticide Resistance Mechanisms In Field Populations Of Malaysian Culex Quinquefasciatus Say (Diptera: Culicidae), Van Lun Low, Chee Dhang Chen, Han Lim Lee, Tiong Kai Tan, Chin Fong Chen, Cherng Shii Leong, Yvonne Ai Lian Lim, Phaik Eem Lim, Yusoff Norma-Rashid, Mohd Sofian-Azirun

Research Publications (2011 to 2015)

Background: There has been no comprehensive study on biochemical characterization of insecticide resistance mechanisms in field populations of Malaysian Culex quinquefasciatus. To fill this void in the literature, a nationwide investigation was performed to quantify the enzyme activities, thereby attempting to characterize the potential resistance mechanisms in Cx. quinquefasciatus in residential areas in Malaysia. Methodology/Principal Findings: Culex quinquefasciatus from 14 residential areas across 13 states and one federal territory were subjected to esterases, mixed function oxidases, glutathione-S-transferase and insensitive acetylcholinesterase assays. Enzyme assays revealed that alpha-esterases and beta-esterases were elevated in 13 populations and 12 populations, respectively. Nine populations demonstrated …

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Fitting Multiphasic Logistic Functions To The Lactation Curves Of Gir X Friesian Crossbred Dairy Cattle In Malaysia, A.M. Majid, A.A. Shariff, A.F. Merican, Y.B. Bong Jan 2013

Fitting Multiphasic Logistic Functions To The Lactation Curves Of Gir X Friesian Crossbred Dairy Cattle In Malaysia, A.M. Majid, A.A. Shariff, A.F. Merican, Y.B. Bong

Research Publications (2011 to 2015)

The data used in this study consisted of milk yield (kg) taken at approximately fortnightly intervals from Gir x Friesian crossbred dairy cattle raised at Institut Haiwan Kluang, Malaysia. The data were first edited, smoothed and then fitted with mono-, di- and triphasic logistic functions. In general, parameter estimates for the first lactation were reasonable. However, for the second lactation the estimates were erratic and unreasonable because this was an atypical lactation for which the multiphasic functions were obviously unsuitable. Residual mean squares for the di- and triphasic functions of the first lactation were very similar (0.0002 and 0.0004, respectively) …

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Foraging Behaviour Of Five Egret Species In Pome Pond Area At Carey Island, Peninsular Malaysia, A.B.H. Aboushiba, R. Ramli, Mohd Sofian-Azirun Jan 2013

Foraging Behaviour Of Five Egret Species In Pome Pond Area At Carey Island, Peninsular Malaysia, A.B.H. Aboushiba, R. Ramli, Mohd Sofian-Azirun

Research Publications (2011 to 2015)

The foraging behaviour of five egret species in four POME ponds at Carey Island, Peninsular Malaysia was observed using 10 x 42 binoculars and digital video camera. The highest probing activity was recorded during 0900 to 1000hrs in Little Egret (Egretta garzetta; i.e. 52 probes/minute) followed by Cattle Egret (Bubulcus cormorandus; i.e. 42 probes/minute), Intermediate Egret (Mesophoyx intermedia; i.e. 20 probes/minute), Chinese Egret (Egretta eulophotes; i.e. 19 probes/minute) and Great Egret (Casmerodius albus; i.e. 5 probes/minute). In contrast, the lowest mean probing activity was recorded in Great Egret (0.4 probe/minute) as compared to Chinese Egret (1 probe/minute), Cattle Egret (2 …

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Gastroprotection Studies Of Schiff Base Zinc (Ii) Derivative Complex Against Acute Superficial Hemorrhagic Mucosal Lesions In Rats, S. Golbabapour, N.S. Gwaram, P. Hassandarvish, M. Hajrezaie, B. Kamalidehghan, M.A. Abdulla, H.M. Ali, A.H.A. Hadi, N.A. Majid Jan 2013

Gastroprotection Studies Of Schiff Base Zinc (Ii) Derivative Complex Against Acute Superficial Hemorrhagic Mucosal Lesions In Rats, S. Golbabapour, N.S. Gwaram, P. Hassandarvish, M. Hajrezaie, B. Kamalidehghan, M.A. Abdulla, H.M. Ali, A.H.A. Hadi, N.A. Majid

Research Publications (2011 to 2015)

Background: The study was carried out to assess the gastroprotective effect of the zinc (II) complex against ethanol-induced acute hemorrhagic lesions in rats. Methodology/Principal Finding: The animals received their respective pre-treatments dissolved in tween 20 (5% v/v), orally. Ethanol (95% v/v) was orally administrated to induce superficial hemorrhagic mucosal lesions. Omeprazole (5.79061025 M/kg) was used as a reference medicine. The pre-treatment with the zinc (II) complex (2.18161025 and 4.36261025 M/kg) protected the gastric mucosa similar to the reference control. They significantly increased the activity levels of nitric oxide, catalase, superoxide dismutase, glutathione and prostaglandin E2, and decreased the level of …

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Gene Expression Profiling Reveals Underlying Molecular Mechanism Of Hepatoprotective Effect Of Phyllanthus Niruri On Thioacetamide-Induced Hepatotoxicity In Sprague Dawley Rats, Z.A. Amin, M.A. Alshawsh, M. Kassim, Mahmood Ameen Abdulla, H.M. Ali Jan 2013

Gene Expression Profiling Reveals Underlying Molecular Mechanism Of Hepatoprotective Effect Of Phyllanthus Niruri On Thioacetamide-Induced Hepatotoxicity In Sprague Dawley Rats, Z.A. Amin, M.A. Alshawsh, M. Kassim, Mahmood Ameen Abdulla, H.M. Ali

Research Publications (2011 to 2015)

Background: The liver plays an essential role in the body by regulating several important metabolic functions. Liver injury is associated with the distortion of these functions causing many health problems. Pharmaceutical drugs treat liver disorders but cause further damage to it. Hence, herbal drugs are used worldwide and are becoming increasingly popular. Methods: The hepatoprotective activity of Phyllanthus niruri (PN) was evaluated against liver cirrhosis induced by thioacetamide (TAA) in male Sprague Dawley rats. Rats received intraperitoneal injections of thioacetamide (TAA, 200 mg/kg, b.w. three times weekly) for eight weeks. Daily treatments with plant extract (200 mg/kg) were administered orally …

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Genome Wide Analysis Of Chromosomal Alterations In Oral Squamous Cell Carcinomas Revealed Over Expression Of Mgam And Adam9, V.K. Vincent-Chong, A. Anwar, L.P. Karen-Ng, S.C. Cheong, Y.H. Yang, P.J. Pradeep, Z.A.A. Rahman, S.M. Ismail, Z.M. Zaini, N. Prepageran, T.G. Kallarakkal, A. Ramanathan, N.A.B.M Mohayadi, N.S.B.M. Rosli, W.M.W. Mustafa, M.T. Abraham, K.K. Tay, R.B. Zain Jan 2013

Genome Wide Analysis Of Chromosomal Alterations In Oral Squamous Cell Carcinomas Revealed Over Expression Of Mgam And Adam9, V.K. Vincent-Chong, A. Anwar, L.P. Karen-Ng, S.C. Cheong, Y.H. Yang, P.J. Pradeep, Z.A.A. Rahman, S.M. Ismail, Z.M. Zaini, N. Prepageran, T.G. Kallarakkal, A. Ramanathan, N.A.B.M Mohayadi, N.S.B.M. Rosli, W.M.W. Mustafa, M.T. Abraham, K.K. Tay, R.B. Zain

Research Publications (2011 to 2015)

Despite the advances in diagnosis and treatment of oral squamous cell carcinoma (OSCC), mortality and morbidity rates have not improved over the past decade. A major drawback in diagnosis and treatment of OSCC is the lack of knowledge relating to how genetic instability in oral cancer genomes affects oral carcinogenesis. Hence, the key aim of this study was to identify copy number alterations (CNAs) that may be cancer associated in OSCC using high-resolution array comparative genomic hybridization (aCGH). To our knowledge this is the first study to use ultra-high density aCGH microarrays to profile a large number of OSCC genomes …

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Health Innovation For Patient Safety Improvement, Renukha Sellappans, Siew Siang Chua, Nur Amani Ahmad Tajuddin, Pauline Siew Mei Lai Jan 2013

Health Innovation For Patient Safety Improvement, Renukha Sellappans, Siew Siang Chua, Nur Amani Ahmad Tajuddin, Pauline Siew Mei Lai

Research Publications (2011 to 2015)

Medication error has been identified as a major factor affecting patient safety. Many innovative efforts such as Computerised Physician Order Entry (CPOE), a Pharmacy Information System, automated dispensing machines and Point of Administration Systems have been carried out with the aim of improving medication safety. However, areas remain that require urgent attention. One main area will be the lack of continuity of care due to the breakdown of communication between multiple healthcare providers. Solutions may include consideration of "health smart cards" that carry vital patient medical information in the form of a "credit card" or use of the Malaysian identification …

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High Quality Cdna Synthesis And Amplification Of Chalcone Synthase Gene (Chs) From Justicia Gendarussa Burm. F., B. Arman Amani, M. S. Faezah Jan 2013

High Quality Cdna Synthesis And Amplification Of Chalcone Synthase Gene (Chs) From Justicia Gendarussa Burm. F., B. Arman Amani, M. S. Faezah

Research Publications (2011 to 2015)

Chalcone synthase (CHS) (EC 2.3.1.74) catalyzes the first committed step of flavonoid biosynthesis pathway. It combines 4-coumaroyl-CoA with three C2 units from malonyl-CoA to produce naringenin chalcone which transforms to various numbers of flavonoids. In this work, we attempt to isolate the CHS gene from Gendarusa, which could serve as a preliminary study to elucidate the CHS gene regulation in the flavonoid biosynthetic pathway of Malaysian medicinal plants generally, and in Justicia gendarussa Burm. F. species specifically. The total RNA was isolated from the mature leaves of Justicia gendarussa Burm. F. using the modified CTAB method. Extracted RNA, treated with …

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Immune Response In Infants After Universal Hepatitis B Vaccination: A Community-Based Study In Malaysia, H.K. Cheang, H.T. Wong, S.C. Ho, K.S. Chew, W.S. Lee Jan 2013

Immune Response In Infants After Universal Hepatitis B Vaccination: A Community-Based Study In Malaysia, H.K. Cheang, H.T. Wong, S.C. Ho, K.S. Chew, W.S. Lee

Research Publications (2011 to 2015)

INTRODUCTION This study aimed to assess the immune response in infants who received the three-shot hepatitis B vaccine in Malaysia. METHODS Consecutive infants born between March 2002 and April 2010 who received three doses of hepatitis B vaccine at a community clinic in Malaysia were enrolled in the study. Screening for hepatitis B surface antigen (HBsAg) and antibody against HBsAg (anti-HBs) was performed after the completion of primary immunisation, at approximately one year of age. RESULTS A total of 572 infants (median age 9.3 +/- 2.7 months; range 6.3-48 months) were screened for immune response to hepatitis B vaccination - …

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In Vitro Induction And Proliferation Of Adventitious Roots In Pineapple (Ananas Comosus L.) Cultivars Of Smooth Cayenne And Morris, A.H.M. Hamad, R.M. Taha, S. Mohajer Jan 2013

In Vitro Induction And Proliferation Of Adventitious Roots In Pineapple (Ananas Comosus L.) Cultivars Of Smooth Cayenne And Morris, A.H.M. Hamad, R.M. Taha, S. Mohajer

Research Publications (2011 to 2015)

The effect of shoot age (6 and 10-month-old) in quarter, half and full strength of two MS medium types (solid, liquid) supplemented with different concentrations of auxins and cytokinins on two pineapple cultivars (Smooth Cayenne and Morris) were examined to identify the optimal combination for root formation. All the shoots of both cultivars rooted in solid medium enriched with 2.0 mg/L IBA at quarter strength for Smooth Cayenne and half strength for Morris. Full strength solid medium enriched with 1.0 mg/L NAA was the best choice for rooting of both Smooth Cayenne and Morris, resulting in the tallest plantlets (74.1 …

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Infection Of Burkholderia Cepacia Induces Homeostatic Responses In The Host For Their Prolonged Survival: The Microarray Perspective, V. Mariappan, K.M. Vellasamy, J. Thimma, Onn Haji Hashim, J. Vadivelu Jan 2013

Infection Of Burkholderia Cepacia Induces Homeostatic Responses In The Host For Their Prolonged Survival: The Microarray Perspective, V. Mariappan, K.M. Vellasamy, J. Thimma, Onn Haji Hashim, J. Vadivelu

Research Publications (2011 to 2015)

Burkholderia cepacia is an opportunistic human pathogen associated with life-threatening pulmonary infections in immunocompromised individuals. Pathogenesis of B. cepacia infection involves adherence, colonisation, invasion, survival and persistence in the host. In addition, B. cepacia are also known to secrete factors, which are associated with virulence in the pathogenesis of the infection. In this study, the host factor that may be the cause of the infection was elucidated in human epithelial cell line, A549, that was exposed to live B. cepacia (mid-log phase) and its secretory proteins (mid-log and early-stationary phases) using the Illumina Human Ref-8 microarray platform. The non-infection A549 …

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Intimate Coupling Of Electro And Biooxidation Of Tannery Wastewater, S. Kanagasabi, Y.L. Kang, M. Manickam, S. Ibrahim, S. Pichiah Jan 2013

Intimate Coupling Of Electro And Biooxidation Of Tannery Wastewater, S. Kanagasabi, Y.L. Kang, M. Manickam, S. Ibrahim, S. Pichiah

Research Publications (2011 to 2015)

Tannery wastewater contains high organic loadings and other pollutants, making it challenging to be treated efficiently. A combined process involving both advance oxidation process and biological treatment seems to be the best solution to achieve the regulatory standard for discharge. This investigation reports on the degradation of tannery wastewater which was represented by the removal Chemical Oxygen Demand (COD) using electrochemical process, biological degradation and finally, the combination of both processes. Electrolysis was carried out in batch reactor under different current density and dilution. Biological degradation was carried out with three isolated microbial strain and optimization of pH, nutrients, and …

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Knowledge Of Sexually Transmitted Diseases And Sexual Behaviours Among Malaysian Male Youths, H. Awang, L.P. Wong, R. Jani, W.Y. Low Jan 2013

Knowledge Of Sexually Transmitted Diseases And Sexual Behaviours Among Malaysian Male Youths, H. Awang, L.P. Wong, R. Jani, W.Y. Low

Research Publications (2011 to 2015)

Summary This study examines the knowledge of sexually transmitted diseases (STDs) among male youths in Malaysia. A self-administered survey was carried out on a sample of 952 never-married males aged 15-24 years. The respondents were asked about their knowledge of STDs, how these diseases get transmitted and their sexual behaviours. The data showed that 92 of the respondents knew of at least one STD (syphilis, gonorrhoea, chlamydia, herpes, genital warts, yeast infection, trichomoniasis or HIV/AIDS). About 95 of them knew of at least one method of STD transmission. Urban and tertiary-educated male youths showed a substantially higher proportion of awareness …

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Lack Of Association Between Tyk2 And Stat3 Genes And Crohn's Disease In The Malaysian Population, L.H. Lian, T.P. Lau, V.L. Lee, W.S. Lee, I. Hilmi, K.L. Goh, K.H. Chua Jan 2013

Lack Of Association Between Tyk2 And Stat3 Genes And Crohn's Disease In The Malaysian Population, L.H. Lian, T.P. Lau, V.L. Lee, W.S. Lee, I. Hilmi, K.L. Goh, K.H. Chua

Research Publications (2011 to 2015)

This study aimed to investigate the potential association of TYK2 and STAT3 genes with the susceptibility to Crohn's disease (CD) among Malaysians. DNA samples were obtained from 80 CD patients and 100 healthy controls. Polymerase chain reaction-restriction fragment length polymorphism methods were employed for genotyping, followed by statistical analysis. In our current study, none of the single nucleotide polymorphisms of either TYK2 or STAT3 was statistically associated with the susceptibility to CD in our local population (P > 0.05). In contrast, there was a statistically significant association between the G/G homozygotes of the STAT3 rs2293152 and the healthy control group (chi(2) …

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Loop-Mediated Isothermal Amplification Assay For Rapid Detection Of Staphylococcus Aureus, K.T. Lim, C.S.J. Teh, Kwai Lin Thong Jan 2013

Loop-Mediated Isothermal Amplification Assay For Rapid Detection Of Staphylococcus Aureus, K.T. Lim, C.S.J. Teh, Kwai Lin Thong

Research Publications (2011 to 2015)

No abstract provided.

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Molecular Characterization Of Salmonella Enterica Serovar Typhimurium Isolated From Human, Food, And Animal Sources In Malaysia, Soo Tein Ngoi, Bjørn-Arne Lindstedt, Haruo Watanabe, Kwai Lin Thong Jan 2013

Molecular Characterization Of Salmonella Enterica Serovar Typhimurium Isolated From Human, Food, And Animal Sources In Malaysia, Soo Tein Ngoi, Bjørn-Arne Lindstedt, Haruo Watanabe, Kwai Lin Thong

Research Publications (2011 to 2015)

Salmonella Typhimurium is an important nontyphoidal Salmonella serovar associated with foodborne diseases in many parts of the world. This organism is the major causative agent of nontyphoidal salmonellosis in Malaysia. We aimed to investigate the genetic profiles of the strains isolated from clinical, zoonotic, and dietary sources in Malaysia using multilocus variable number tandem repeat analysis (MLVA) and pulsed-field gel electrophoresis (PFGE). By focusing on the 5 common variable number tandem repeat (VNTR) loci, we found that PFGE (D = 0.99) was more discriminative than MLVA (D = 0.76). The low MLVA score might be because of a lack of …

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Molecular Signatures Of T-Cell Inhibition In Hiv-1 Infection, M. Larsson, E.M. Shankar, K.F. Che, A. Saeldi, R. Ellegard, M. Barathan, V. Velu, A. Kamarulzaman Jan 2013

Molecular Signatures Of T-Cell Inhibition In Hiv-1 Infection, M. Larsson, E.M. Shankar, K.F. Che, A. Saeldi, R. Ellegard, M. Barathan, V. Velu, A. Kamarulzaman

Research Publications (2011 to 2015)

Cellular immune responses play a crucial role in the control of viral replication in HIV-infected individuals. However,the virus succeeds in exploiting the immune system to its advantage and therefore, the host ultimately fails to control the virus leading to development of terminal AIDS. The virus adopts numerous evasion mechanisms to hijack the host immune system. We and others recently described the expression of inhibitory molecules on T cells as a contributing factor for suboptimal T-cell responses in HIV infection both in vitro and in vivo. The expression of these molecules that negatively impacts the normal functions of the host immune …

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Mosquito Species And Outdoor Breeding Places In Residential Areas In Malaysia, S.N.R. Saleeza, Y. Norma-Rashid, Mohd Sofian-Azirun Jan 2013

Mosquito Species And Outdoor Breeding Places In Residential Areas In Malaysia, S.N.R. Saleeza, Y. Norma-Rashid, Mohd Sofian-Azirun

Research Publications (2011 to 2015)

We conducted mosquito surveillance at outdoor breeding habitat in 459 households at 7 urban locations in Putrajaya, Malaysia from January to December 2010 to determine the predominant species and breeding locations. The most common species found at all locations was Aedes albopictus. Gardening utensils were the most common breeding sites. Of the 1,885 mosquito larvae specimens found, 1,774 (94.1) were Ae. albopictus larvae, 84 (4) were Ae. aegypti larvae and 27 (1) were Culex quinquefasciatus larvae. The Aedes index for each of the locations was higher than the goal set by the Ministry of Health for Malaysia. However, the container …

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Multi-Level 3d Implementation Of Thermo-Pneumatic Pumping On Centrifugal Microfluidic Cd Platforms, T.H.G. Thio, F. Ibrahim, W. Al-Faqheri, N. Soin, M.K.B. Abdul Kahar, M. Madou Jan 2013

Multi-Level 3d Implementation Of Thermo-Pneumatic Pumping On Centrifugal Microfluidic Cd Platforms, T.H.G. Thio, F. Ibrahim, W. Al-Faqheri, N. Soin, M.K.B. Abdul Kahar, M. Madou

Research Publications (2011 to 2015)

Thermo-pneumatic (TP) pumping is a method employing the principle of expanding heated air to transfer fluids back towards the CD center on the centrifugal microfluidic CD platform. While the TP features are easy to fabricate as no moving parts are involved, it consumes extra real estate on the CD, and because heating is involved, it introduces unnecessary heating to the fluids on the CD. To overcome these limitations, we introduce a multi-level 3D approach and implement forced convection heating. In a multi-level 3D CD, the TP features are relocated to a separate top level, while the microfluidic process remains on …

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Muscle Spindle Discharge Pattern From Jaw-Closing Muscles During Chewing Different Hardness Of Foods In Awake Rabbits., H.M. Zakir Jan 2013

Muscle Spindle Discharge Pattern From Jaw-Closing Muscles During Chewing Different Hardness Of Foods In Awake Rabbits., H.M. Zakir

Research Publications (2011 to 2015)

No abstract provided.

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Novel Liquid Equilibrium Valving On Centrifugal Microfluidic Cd Platform, W. Al-Faqheri, F. Ibrahim, T.H.G. Thio, Hamzah Arof, M. Madou Jan 2013

Novel Liquid Equilibrium Valving On Centrifugal Microfluidic Cd Platform, W. Al-Faqheri, F. Ibrahim, T.H.G. Thio, Hamzah Arof, M. Madou

Research Publications (2011 to 2015)

One of the main challenges faced by researchers in the field of microfluidic compact disc (CD) platforms is the control of liquid movement and sequencing during spinning. This paper presents a novel microfluidic valve based on the principle of liquid equilibrium on a rotating CD. The proposed liquid equilibrium valve operates by balancing the pressure produced by the liquids in a source and a venting chamber during spinning. The valve does not require external forces or triggers, and is able to regulate burst frequencies with high accuracy. In this work, we demonstrate that the burst frequency can be significantly raised …

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Numerical Investigation Of The Plasma-Aided Fabrication Of Stoichiometric Inas Nanodots At Early Stage Of The Growth, M. Alizadeh, H. Mehdipour, B.T. Goh, S.A. Rahman Jan 2013

Numerical Investigation Of The Plasma-Aided Fabrication Of Stoichiometric Inas Nanodots At Early Stage Of The Growth, M. Alizadeh, H. Mehdipour, B.T. Goh, S.A. Rahman

Research Publications (2011 to 2015)

Using numerical modeling of the plasma sheath and key surface processes, the plasma-aided fabrication of InAs nanodots is investigated at early stage of the growth. Roles of different plasma process parameters, such as electron temperature, electron number density, and ion-to-electron density ratio, in achieving the stoichiometric growth of the nanodots are explored and conditions to achieve a highly stoichiometric InAs composition are discussed. It is shown that the nanodots get larger with increasing the electron temperature and electron number density, whereas they shrink in size with increasing the ion-to-electron density ratio. Moreover, it is shown that with increase in the …

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Optimization Of Reactive Dyes Degradation By Fenton Oxidation Using Response Surface Method, Archina Buthiyappan, Abdul Aziz Abdul Raman, Wan Mohd Ashri Wan Daud Jan 2013

Optimization Of Reactive Dyes Degradation By Fenton Oxidation Using Response Surface Method, Archina Buthiyappan, Abdul Aziz Abdul Raman, Wan Mohd Ashri Wan Daud

Research Publications (2011 to 2015)

The objective of this study is to determine the influence of various parameters on the degradation of dye (with high COD value) by using Fenton process. Design of experiment was applied for the optimization with respect to: initial concentration of Fe2+ and H2O2 to ascertain their respective effects on the treatment efficiency. The progress of dye degradation was analyzed by monitoring the Chemical Oxygen Demand (COD). The experimental results show that the initial concentration of H2O2, and Fe2+, had great influence on degradation of dye by Fenton process. Application of optimum operation conditions of: Fe2+/Dye = 10 and Fe2+/H2O2= 25 …

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Oral Cancer Prognosis Based On Clinicopathologic And Genomic Markers Using A Hybrid Of Feature Selection And Machine Learning Methods, S.W. Chang, S. Abdul-Kareem, A.F. Merican, R.B. Zain Jan 2013

Oral Cancer Prognosis Based On Clinicopathologic And Genomic Markers Using A Hybrid Of Feature Selection And Machine Learning Methods, S.W. Chang, S. Abdul-Kareem, A.F. Merican, R.B. Zain

Research Publications (2011 to 2015)

Background: Machine learning techniques are becoming useful as an alternative approach to conventional medical diagnosis or prognosis as they are good for handling noisy and incomplete data, and significant results can be attained despite a small sample size. Traditionally, clinicians make prognostic decisions based on clinicopathologic markers. However, it is not easy for the most skilful clinician to come out with an accurate prognosis by using these markers alone. Thus, there is a need to use genomic markers to improve the accuracy of prognosis. The main aim of this research is to apply a hybrid of feature selection and machine …

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Patronage Politics, Plantation Fires And Transboundary Haze, H. Varkkey Jan 2013

Patronage Politics, Plantation Fires And Transboundary Haze, H. Varkkey

Research Publications (2011 to 2015)

Since 1982, haze pollution has become an almost annual occurrence in Southeast Asia, with the worst episodes being in the period of 1997–1998 and in 2006–2007. Haze originates from peat and forest fires, mostly in Indonesia. The negative effects of haze can be observed at the global level, with increased carbon emissions exacerbating climate change, and more importantly at the regional level, with serious environmental and socioeconomic effects in Indonesia and its neighbouring countries. Most of these fires are manmade, and can be traced back to land clearing activities of commercial oil palm plantations. This article questions why these companies …

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Persistent Immune Activation In Chronic Hiv Infection: Do Any Interventions Work?, R. Rajasuriar, G. Khoury, A. Kamarulzaman, M.A. French, P.U. Cameron, S.R. Lewin Jan 2013

Persistent Immune Activation In Chronic Hiv Infection: Do Any Interventions Work?, R. Rajasuriar, G. Khoury, A. Kamarulzaman, M.A. French, P.U. Cameron, S.R. Lewin

Research Publications (2011 to 2015)

No abstract provided.

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Prevalence And Antimicrobial Susceptibility Of Salmonella Spp. Isolated From Snakes In Peninsular, Malaysia, M.G. Abatcha, Z. Zakaria, D.G. Kaur, Kwai Lin Thong Jan 2013

Prevalence And Antimicrobial Susceptibility Of Salmonella Spp. Isolated From Snakes In Peninsular, Malaysia, M.G. Abatcha, Z. Zakaria, D.G. Kaur, Kwai Lin Thong

Research Publications (2011 to 2015)

No abstract provided.

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Protein Markers Useful In Authenticating Eurycoma Longifolia Contained Herbal Aphrodisiac Products, J. Vejayan, V. Iman, S.L. Foong, H. Ibrahim Jan 2013

Protein Markers Useful In Authenticating Eurycoma Longifolia Contained Herbal Aphrodisiac Products, J. Vejayan, V. Iman, S.L. Foong, H. Ibrahim

Research Publications (2011 to 2015)

Eurycoma longifolia has been widely recognized for its aphrodisiac benefits and many herbal products incorporated with its extract been sold worldwide. The products in various forms of capsules or spherical tablets were appropriately solubilized in water and their protein content were separated using two dimensional electrophoresis (IPG strip of pI 3-10; 15% homogenous gel) and stained in coomassie blue. In this study using a standardized extract known for its biological activity, CFPR-JV1, two distinctive protein markers were detected within 2DE gel. The markers were spots found approximately at molecular weight of 14kDa at the basic extremities. The markers were not …

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Push Pull Microfluidics On A Multi-Level 3d Cd, T.H.G. Thio, F. Ibrahim, W. Al-Faqheri, J. Moebius, N.S. Khalid, N. Soin, M.K.B.A. Kahar, M. Madou Jan 2013

Push Pull Microfluidics On A Multi-Level 3d Cd, T.H.G. Thio, F. Ibrahim, W. Al-Faqheri, J. Moebius, N.S. Khalid, N. Soin, M.K.B.A. Kahar, M. Madou

Research Publications (2011 to 2015)

A technique known as thermo-pneumatic (TP) pumping is used to pump fluids on a microfluidic compact disc (CD) back towards the CD center against the centrifugal force that pushes liquids from the center to the perimeter of the disc. Trapped air expands in a TP air chamber during heating, and this creates positive pressure on liquids located in chambers connected to that chamber. While the TP air chamber and connecting channels are easy to fabricate in a one-level CD manufacturing technique, this approach provides only one way pumping between two chambers, is real-estate hungry and leads to unnecessary heating of …

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