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2013

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Modeling Sediment Accumulation In North American Playa Wetlands In Response To Climate Change, 1940–2100, Lucy Burris, Susan K. Skagen Jan 2013

Modeling Sediment Accumulation In North American Playa Wetlands In Response To Climate Change, 1940–2100, Lucy Burris, Susan K. Skagen

United States Geological Survey: Staff Publications

Playa wetlands on the west-central Great Plains of North America are vulnerable to sediment infilling from upland agriculture, putting at risk several important ecosystem services as well as essential habitats and food resources of diverse wetland-dependent biota. Climate predictions for this semi-arid area indicate reduced precipitation which may alter rates of erosion, runoff, and sedimentation of playas. We forecasted erosion rates, sediment depths, and resultant playa wetland depths across the west-central Great Plains and examined the relative roles of land use context and projected changes in precipitation in the sedimentation process. We estimated erosion with the Revised Universal Soil Loss …

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Tracking Transplanted Bone Marrow Stem Cells And Their Effects In The Rat Mcao Stroke Model., Gregory V Goldmacher, Rena Nasser, Daniel Y Lee, Sargon Yigit, Robert Rosenwasser, Lorraine Iacovitti Jan 2013

Tracking Transplanted Bone Marrow Stem Cells And Their Effects In The Rat Mcao Stroke Model., Gregory V Goldmacher, Rena Nasser, Daniel Y Lee, Sargon Yigit, Robert Rosenwasser, Lorraine Iacovitti

Farber Institute for Neuroscience Faculty Papers

In this study, rat bone marrow stromal stem cells (BMSCs) were tracked after IV administration to rats with experimental stroke caused by middle cerebral artery occlusion (MCAO). In addition, the effects of BMSC treatment on blood cell composition, brain glia and sensorimotor behavior was studied and compared to that which occurred spontaneously during the normal recovery process after stroke. We found that the vast majority of radiolabeled or fluorescently labeled BMSCs traveled to and remained in peripheral organs (lungs, spleen, liver) 3 days after IV injection in the MCAO rat. Once in the circulation, BMSCs also produced rapid alterations in …

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The Effectiveness Of Virtual Learning Tools For Millennial Generation Students In A Community College Criminal Justice Degree Program, Lawrence Snyder Jan 2013

The Effectiveness Of Virtual Learning Tools For Millennial Generation Students In A Community College Criminal Justice Degree Program, Lawrence Snyder

CCAC Theses and Dissertations

An analysis of data from the Community College Survey of Student Engagement and multiyear analysis of pretest/posttest scores in introductory criminal justice courses revealed there was a systemic decline in student engagement and achievement. Because of this analysis, a commercial virtual learning tool (CJI) that purported great success in improving student engagement and performance was identified and implemented on the college's course management application in the spring of 2010. CJI, a comprehensive learning tool that incorporated Web 2.0 activities, such as video, simulations, and study aids, was designed to improve student engagement and performance. The inclusion of Web 2.0 activities …

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Online Deception Detection Using Bdi Agents, Richard Alan Merritts Jan 2013

Online Deception Detection Using Bdi Agents, Richard Alan Merritts

CCAC Theses and Dissertations

This research has two facets within separate research areas. The research area of Belief, Desire and Intention (BDI) agent capability development was extended. Deception detection research has been advanced with the development of automation using BDI agents. BDI agents performed tasks automatically and autonomously. This study used these characteristics to automate deception detection with limited intervention of human users. This was a useful research area resulting in a capability general enough to have practical application by private individuals, investigators, organizations and others. The need for this research is grounded in the fact that humans are not very effective at detecting …

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Revisiting The Meaning Of Marriage: Immigration For Same-Sex Spouses In A Post-Windsor World, Scott Titshaw Jan 2013

Revisiting The Meaning Of Marriage: Immigration For Same-Sex Spouses In A Post-Windsor World, Scott Titshaw

Vanderbilt Law Review En Banc

No abstract provided.

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Synthesis And Evaluation Of Some 17-Acetamidoandrostane And N,N-Dimethyl-7-Deoxycholic Amide Derivatives As Cytotoxic Agents: Structure/Activity Studies, Yanmin Huang, Jianguo Cui, Linyi Jia, Chunfang Gan, Huacan Song, Chun Zeng, Aimin Zhou Jan 2013

Synthesis And Evaluation Of Some 17-Acetamidoandrostane And N,N-Dimethyl-7-Deoxycholic Amide Derivatives As Cytotoxic Agents: Structure/Activity Studies, Yanmin Huang, Jianguo Cui, Linyi Jia, Chunfang Gan, Huacan Song, Chun Zeng, Aimin Zhou

Chemistry Faculty Publications

Using pregnenolone and 7-deoxycholic acid as starting materials, some 17-acetamidoandrostane and N,N-dimethyl-7-deoxycholic amide derivatives were synthesized. The cytotoxicity of the synthesized compounds was tested in vitro against two tumor cell lines: SGC 7901 (human gastric carcinoma) and Bel 7404 (human liver carcinoma). The result showed that the blockage of the interaction of the amide group with outside groups might cause a decrease of the cytotoxicity, and an O-benzyloximino group at the 3-position of N,N-dimethyl-7-deoxycholic amide could enhance the cytotoxic activity of the compound. The information obtained from the studies provides the structure-activity relationship for these compounds and may be useful …

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Emerging In The Image Of God: From Evolution To Ethics In A Second Naïveté Understanding Of Christian Anthropology, Jason Paul Roberts Jan 2013

Emerging In The Image Of God: From Evolution To Ethics In A Second Naïveté Understanding Of Christian Anthropology, Jason Paul Roberts

Dissertations (1934 -)

Through a careful integration of theological, philosophical, and the natural scientific sources, the biblical concepts of the image of God and the knowledge of good and evil have the potential to remain important and appropriate descriptors of the human condition, including the possibility and necessity of human morality. This study employs French philosopher Paul Ricoeur's notion of "second naïveté" understanding to demonstrate the hermeneutical significance of contemporary biocultural evolutionary theory for reinterpreting and reappropriating these ancient symbols of Christian anthropology as terms equipped to encapsulate a morally fruitful and intellectually honest conceptual framework for constructing, conducting, and evaluating theological anthropology …

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Commencement 2013, Sacred Heart University Jan 2013

Commencement 2013, Sacred Heart University

Commencement Programs

Program for the Graduate and Undergraduate ceremonies held May 18-19 2013.

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Toward Comprehensive Reform Of America's Emergency Law Regime, Patrick A. Thronson Jan 2013

Toward Comprehensive Reform Of America's Emergency Law Regime, Patrick A. Thronson

University of Michigan Journal of Law Reform

Unbenownst to most Americans, the United States is presently under thirty presidentially declared states of emergency. They confer vast powers on the Executive Branch, including the ability to financially incapacitate any person or organization in the United States, seize control of the nation's communications infrastructure, mobilize military forces, expand the permissible size of the military without congressional authorization, and extend tours of duty without consent from service personnel. Declared states of emergency may also activate Presidential Emergency Action Documents and other continuity-of-government procedures, which confer powers on the President-such as the unilateral suspension of habeas corpus-that appear fundamentally opposed to …

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2013 Biennial Faculty Activities Report, University Of Northern Iowa, University Of Iowa, Iowa State University Jan 2013

2013 Biennial Faculty Activities Report, University Of Northern Iowa, University Of Iowa, Iowa State University

Institutional Effectiveness & Planning Documents

Report of faculty activity broken down by rank and compared to the other Regents institutions

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Population Briefs, Vol. 19, No. 3, Population Council Jan 2013

Population Briefs, Vol. 19, No. 3, Population Council

Population Briefs

IN THIS ISSUE: Family planning road map points way to equitable access | Improving adherence in microbicide clinical trials: Lessons learned and recommendations | Increasing girls’ protective assets in rural Upper Egypt | Menstruation accounts for only small proportion of girls’ absenteeism in Malawi, study suggests

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Best Practices In Writing Assessment For Instruction, Robert C. Calfee, Roxanne Greitz Miller Jan 2013

Best Practices In Writing Assessment For Instruction, Robert C. Calfee, Roxanne Greitz Miller

Education Faculty Books and Book Chapters

Our assignment in this chapter is to discuss best practices in writing assessment, a task that poses a twofold challenge for teachers-first, the task of providing authentic opportunities for students to acquire skill in writing while covering an ever-increasing array of other curriculum demands; second, the overriding pressures to ensure that students perform well on the standardized tests that have become the primary accountability index. As we complete this chapter, few state testing systems rely to any significant degree on performance tests for measuring student achievement. Multiple-choice tests dominate, and on-demand writing tests (including the SAT) generally contravene the counsel …

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Impairment Of Trkb-Psd-95 Signaling In Angelman Syndrome, Cong Cao, Mengia S. Rioult-Pedotti, Paolo Migani, Crystal J. Yu, Rakesh Tiwari, Keykavous Parang, Mark R. Spaller, Dennis J. Goebel, John Marshall Jan 2013

Impairment Of Trkb-Psd-95 Signaling In Angelman Syndrome, Cong Cao, Mengia S. Rioult-Pedotti, Paolo Migani, Crystal J. Yu, Rakesh Tiwari, Keykavous Parang, Mark R. Spaller, Dennis J. Goebel, John Marshall

Pharmacy Faculty Articles and Research

Angelman syndrome (AS) is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the proteasomal degradation of proteins implicated in synaptic plasticity, such as the activity-regulated cytoskeletal-associated protein (Arc/Arg3.1). Mice deficient in maternal Ube3A express elevated levels of Arc in response to synaptic activity, which coincides with severely impaired long-term potentiation (LTP) in the hippocampus and deficits in learning behaviors. In this study, we sought to test whether elevated levels of Arc interfere with brain-derived neurotrophic factor (BDNF) …

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Calcium Phosphate Nanoparticles: A Future Therapeutic Platform For The Treatment Of Osteomyelitis?, Tejal A. Dasai, Vuk Uskoković Jan 2013

Calcium Phosphate Nanoparticles: A Future Therapeutic Platform For The Treatment Of Osteomyelitis?, Tejal A. Dasai, Vuk Uskoković

Pharmacy Faculty Articles and Research

No abstract provided.

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Transcriptome Characterization And Detection Of Gene Expression Differences In Aspen (Populus Tremuloides), Hardeep S. Rai, Karen E. Mock, Bryce A. Richardson, Richard C. Cronn, Katherine J. Hayden, Jessica W. Wright, Brian J. Knaus, Paul G. Wolf Jan 2013

Transcriptome Characterization And Detection Of Gene Expression Differences In Aspen (Populus Tremuloides), Hardeep S. Rai, Karen E. Mock, Bryce A. Richardson, Richard C. Cronn, Katherine J. Hayden, Jessica W. Wright, Brian J. Knaus, Paul G. Wolf

Aspen Bibliography

No abstract provided.

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Wolf Creek Ranch Aspen Monitoring Report, Paul C. Rogers, Allison Jones, James Catlin, James Shuler, Arthur Morris, Michael Kuhns Jan 2013

Wolf Creek Ranch Aspen Monitoring Report, Paul C. Rogers, Allison Jones, James Catlin, James Shuler, Arthur Morris, Michael Kuhns

Aspen Bibliography

In the summer of 2012 we undertook a landscape assessment of aspen forest conditions at Wolf Creek Ranch (WCR) near Kamas, Utah. Using a geographic information system (GIS) coverage of predicted aspen coverage, fifty systematically selected field "plots" were located and mapped with aspen stands around WCR. Seven plots were eventually discarded from our survey due to lack of aspen cover. Volunteer field crews, mostly WCR homeowners, collected aspen data documenting tree sizes, height/age groups, diameters, reproduction, mortality, browse levels, and browse animal use levels.

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Aberrant Proliferation In Cxcr7+ Endothelial Cells Via Degradation Of The Retinoblastoma Protein, Jennifer Totonchy, Jessica M. Osborn, Sara Botto, Lisa Clepper, Ashlee V. Moses Jan 2013

Aberrant Proliferation In Cxcr7+ Endothelial Cells Via Degradation Of The Retinoblastoma Protein, Jennifer Totonchy, Jessica M. Osborn, Sara Botto, Lisa Clepper, Ashlee V. Moses

Pharmacy Faculty Articles and Research

Angiogenesis is a critical factor in the growth and dissemination of solid tumors. Indeed, tumor vasculature is abnormal and contributes to the development and spread of malignancies by creating a hostile microenvironment. The alternative SDF-1/CXCL12 receptor, CXCR7, is frequently and specifically expressed in tumor-associated vessels. In this study, we examine the role of endothelium-expressed CXCR7 in tumor vascular dysfunction by specifically examining the contribution of CXCR7 to endothelial cell (EC) proliferation. We demonstrate that CXCR7 expression is sufficient to drive post-confluent growth in EC cultures. Further, we provide a novel mechanism for CXCR7-mediated proliferation via proteasomal degradation of the tumor …

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Corneal Gene Therapy: Basic Science And Translational Perspective, Rajiv R. Mohan, Jason T. Rodier, Ajay Sharma Jan 2013

Corneal Gene Therapy: Basic Science And Translational Perspective, Rajiv R. Mohan, Jason T. Rodier, Ajay Sharma

Pharmacy Faculty Articles and Research

Corneal blindness is the third leading cause of blindness worldwide. Gene therapy is an emerging technology for corneal blindness due to the accessibility and immune-privileged nature of the cornea, ease of vector administration and visual monitoring, and ability to perform frequent noninvasive corneal assessment. Vision restoration by gene therapy is contingent upon vector and mode of therapeutic gene introduction into targeted cells/tissues. Numerous efficacious vectors, delivery techniques, and approaches have evolved in last decade for developing gene-based interventions for corneal diseases. Maximizing the potential benefits of gene therapy requires efficient and sustained therapeutic gene expression in target cells, low toxicity, …

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Parsing Parenthood, Cynthia Godsoe Jan 2013

Parsing Parenthood, Cynthia Godsoe

Faculty Scholarship

No abstract provided.

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The Architecture Of Ignorance, Gregg P. Macey Jan 2013

The Architecture Of Ignorance, Gregg P. Macey

Faculty Scholarship

No abstract provided.

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2012 Breeding Raptor Survey Of The Upper Rio Grande Gorge, Hawks Aloft, Inc. Jan 2013

2012 Breeding Raptor Survey Of The Upper Rio Grande Gorge, Hawks Aloft, Inc.

Multi-Species Reports (Hawks Aloft)

No abstract provided.

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Comparison Of A Plant Based Natural Surfactant With Sds For Washing Of As(V) From Fe Rich Soil, S. Mukhopadhyay, Mohd Ali Hashim, J.N. Sahu, Ismail Yusoff, B. Sen Gupta Jan 2013

Comparison Of A Plant Based Natural Surfactant With Sds For Washing Of As(V) From Fe Rich Soil, S. Mukhopadhyay, Mohd Ali Hashim, J.N. Sahu, Ismail Yusoff, B. Sen Gupta

Research Publications (2011 to 2015)

BACKGROUND: This study explores the possible application of a biodegradable plant based surfactant, obtained from Sapindus mukorossi, for washing low levels of arsenic (As) from an iron (Fe) rich soil. Natural association of As(V) with Fe(III) makes the process difficult. Soapnut solution was compared to anionic surfactant sodium dodecyl sulfate (SDS) in down-flow and a newly introduced suction mode for soil column washing. RESULTS: It was observed that soapnut attained up to 86% efficiency with respect to SDS in removing As. Full factorial design of experiment revealed a very good fit of data. The suction mode generated up to 83 …

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Contour Analysis Of An Implant-Soft Tissue Interface, W.L. Chai, K. Moharamzadeh, R. Van Noort, L. Emanuelsson, A. Palmquist, I.M. Brook Jan 2013

Contour Analysis Of An Implant-Soft Tissue Interface, W.L. Chai, K. Moharamzadeh, R. Van Noort, L. Emanuelsson, A. Palmquist, I.M. Brook

Research Publications (2011 to 2015)

Background and Objective: Studies of peri-implant soft tissue on invivo models are commonly based on histological sections prepared using undecalcified or fracture' techniques. These techniques require the cutting or removal of implant during the specimen preparation process. The aim of this study is to explore a new impression technique that does not require any cutting or removal of implant for contour analysis of soft tissue around four types of titanium (Ti) surface roughness using an invitro three-dimensional oral mucosal model (3D OMM). Methods: The 3D OMM was constructed by co-culturing a keratinocyte cell line TR146 and human oral fibroblasts on …

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Critical Considerations For Fast And Accurate Regiospecific Analysis Of Triacylglycerols Using Quantitative ¹³C Nmr, C.H. Chuah, S.W. Gouk, S.F. Cheng, M. Malon, A.S.H. Ong Jan 2013

Critical Considerations For Fast And Accurate Regiospecific Analysis Of Triacylglycerols Using Quantitative ¹³C Nmr, C.H. Chuah, S.W. Gouk, S.F. Cheng, M. Malon, A.S.H. Ong

Research Publications (2011 to 2015)

Quantitative ¹³C NMR (qCNMR) has been used as an appealing methodology for regiospecific analysis of triacylglycerols in edible oils and fats. It has advantages of shorter analysis time, precision and accuracy over laborious conventional Grignard or enzymatic hydrolysis method. Previous reported studies have recommended diversified NMR acquisition and processing parameters for the same quantification work. Different quantitative data were obtained by using a distinct sets of NMR parameters. To overcome this problem, we conducted a systematic investigation to examine the role of each acquisition and processing parameters to obtain high accuracy and repeatability data. Principal acquisition parameters, for instance pulse …

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Dna Methylation Profiling Revealed Promoter Hypermethylation-Induced Silencing Of P16, Ddah2 And Dusp1 In Primary Oral Squamous Cell Carcinoma, Goot Heah Khor, Gabriele Ruth Anisah Froemming, R.B. Zain, Mannil Thomas Abraham, Effat Omar, Su Keng Tan, Aik Choon Tan, Vincent Vui King Chong, Kwai Lin Thong Jan 2013

Dna Methylation Profiling Revealed Promoter Hypermethylation-Induced Silencing Of P16, Ddah2 And Dusp1 In Primary Oral Squamous Cell Carcinoma, Goot Heah Khor, Gabriele Ruth Anisah Froemming, R.B. Zain, Mannil Thomas Abraham, Effat Omar, Su Keng Tan, Aik Choon Tan, Vincent Vui King Chong, Kwai Lin Thong

Research Publications (2011 to 2015)

BACKGROUND: Hypermethylation in promoter regions of genes might lead to altered gene functions and result in malignant cellular transformation. Thus, biomarker identification for hypermethylated genes would be very useful for early diagnosis, prognosis, and therapeutic treatment of oral squamous cell carcinoma (OSCC). The objectives of this study were to screen and validate differentially hypermethylated genes in OSCC and correlate the hypermethylation-induced genes with demographic, clinocopathological characteristics and survival rate of OSCC. METHODS: DNA methylation profiling was utilized to screen the differentially hypermethylated genes in OSCC. Three selected differentially-hypermethylated genes of p16, DDAH2 and DUSP1 were further validated for methylation status …

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Dna Typing Of Calliphorids Collected From Human Corpses In Malaysia, R. Kavitha, T.C. Tan, H.L. Lee, W.A. Nazni, Mohd Sofian-Azirun Jan 2013

Dna Typing Of Calliphorids Collected From Human Corpses In Malaysia, R. Kavitha, T.C. Tan, H.L. Lee, W.A. Nazni, Mohd Sofian-Azirun

Research Publications (2011 to 2015)

Estimation of post-mortem interval (PMI) is crucial for time of death determination. The advent of DNA-based identification techniques forensic entomology saw the beginning of a proliferation of molecular studies into forensically important Calliphoridae (Diptera). The use of DNA to characterise morphologically indistinguishable immature calliphorids was recognised as a valuable molecular tool with enormous practical utility. The local entomofauna in most cases is important for the examination of entomological evidences. The survey of the local entomofauna has become a fundamental first step in forensic entomological studies, because different geographical distributions, seasonal and environmental factors may influence the decomposition process and the …

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Effect Of Gelam Honey On The Oxidative Stress-Induced Signaling Pathways In Pancreatic Hamster Cells, I.S. Ismail, K. Batumalaie, S.Z. Safi, K. Mohd Yusof, S.D. Sekaran, R. Qvist Jan 2013

Effect Of Gelam Honey On The Oxidative Stress-Induced Signaling Pathways In Pancreatic Hamster Cells, I.S. Ismail, K. Batumalaie, S.Z. Safi, K. Mohd Yusof, S.D. Sekaran, R. Qvist

Research Publications (2011 to 2015)

Oxidative stress induced by reactive oxygen and nitrogen species is critically involved in the impairment of

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Effects Of The Phytoestrogen Genistein On The Development Of The Reproductive System Of Sprague Dawley Rats, S.R.M. Zin, S.Z. Omar, N.L.A. Khan, N.I. Musameh, S. Das, N.M. Kassim Jan 2013

Effects Of The Phytoestrogen Genistein On The Development Of The Reproductive System Of Sprague Dawley Rats, S.R.M. Zin, S.Z. Omar, N.L.A. Khan, N.I. Musameh, S. Das, N.M. Kassim

Research Publications (2011 to 2015)

OBJECTIVES: Genistein is known to influence reproductive system development through its binding affinity for estrogen receptors. The present study aimed to further explore the effect of Genistein on the development of the reproductive system of experimental rats. METHODS: Eighteen post-weaning female Sprague Dawley rats were divided into the following groups: (i) a control group that received vehicle (distilled water and Tween 80); (ii) a group treated with 10 mg/kg body weight (BW) of Genistein (Gen 10); and (iii) a group treated with a higher dose of Genistein (Gen 100). The rats were treated daily for three weeks from postnatal day …

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Efficacy Of Ozonation On Micro-Organisms Disinfection In Well Water Treatment, N.M. Norhayati, S.L. Yap, C.S.J. Teh, Kwai Lin Thong Jan 2013

Efficacy Of Ozonation On Micro-Organisms Disinfection In Well Water Treatment, N.M. Norhayati, S.L. Yap, C.S.J. Teh, Kwai Lin Thong

Research Publications (2011 to 2015)

No abstract provided.

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Enzymatic Characterization Of Insecticide Resistance Mechanisms In Field Populations Of Malaysian Culex Quinquefasciatus Say (Diptera: Culicidae), Van Lun Low, Chee Dhang Chen, Han Lim Lee, Tiong Kai Tan, Chin Fong Chen, Cherng Shii Leong, Yvonne Ai Lian Lim, Phaik Eem Lim, Yusoff Norma-Rashid, Mohd Sofian-Azirun Jan 2013

Enzymatic Characterization Of Insecticide Resistance Mechanisms In Field Populations Of Malaysian Culex Quinquefasciatus Say (Diptera: Culicidae), Van Lun Low, Chee Dhang Chen, Han Lim Lee, Tiong Kai Tan, Chin Fong Chen, Cherng Shii Leong, Yvonne Ai Lian Lim, Phaik Eem Lim, Yusoff Norma-Rashid, Mohd Sofian-Azirun

Research Publications (2011 to 2015)

Background: There has been no comprehensive study on biochemical characterization of insecticide resistance mechanisms in field populations of Malaysian Culex quinquefasciatus. To fill this void in the literature, a nationwide investigation was performed to quantify the enzyme activities, thereby attempting to characterize the potential resistance mechanisms in Cx. quinquefasciatus in residential areas in Malaysia. Methodology/Principal Findings: Culex quinquefasciatus from 14 residential areas across 13 states and one federal territory were subjected to esterases, mixed function oxidases, glutathione-S-transferase and insensitive acetylcholinesterase assays. Enzyme assays revealed that alpha-esterases and beta-esterases were elevated in 13 populations and 12 populations, respectively. Nine populations demonstrated …

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