Digital Commons Network^™

A Simulation-Based Approach For Evaluating And Comparing The Environmental Footprints Of Beef Production Systems, C. A. Rotz, B. J. Isenberg, K. R. Stackhouse-Lawson, E. J. Pollak

Roman L. Hruska U.S. Meat Animal Research Center: Reports

A methodology was developed and used to determine environmental footprints of beef cattle produced at the U.S. Meat Animal Research Center (U.S. Meat Animal Research Center) in Clay Center, NE, with the goal of quantifying improvements achieved over the past 40 yr. Information for U.S. Meat Animal Research Center operations was gathered and used to establish parameters representing their production system with the Integrated Farm System Model. The U.S. Meat Animal Research Center farm, cow–calf, and feedlot operations were each simulated over recent historical weather to evaluate performance, environmental impact, and economics. The current farm operation included 841 ha of …

Breeding And Genetics Symposium: Networks And Pathways To Guide Genomic Selection, W. M. Snelling, R. A. Cushman, J. W. Keele, C. Maltecca, M. G. Thomas, M. R. S. Fortes, A. Reverter

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Many traits affecting profitability and sustainability of meat, milk, and fiber production are polygenic, with no single gene having an overwhelming influence on observed variation. No knowledge of the specific genes controlling these traits has been needed to make substantial improvement through selection. Significant gains have been made through phenotypic selection enhanced by pedigree relationships and continually improving statistical methodology. Genomic selection, recently enabled by assays for dense SNP located throughout the genome, promises to increase selection accuracy and accelerate genetic improvement by emphasizing the SNP most strongly correlated to phenotype although the genes and sequence variants affecting phenotype remain …

Ec13-872 Nebraska 2013 Crop Budgets, Robert N. Klein, Roger K. Wilson

University of Nebraska-Lincoln Extension: Historical Materials

This publication contains crop production budgets for 13 crops and 51 cropping systems, as well as tables of power, machinery, labor, and input costs used to develop these budgets. Each budget consists of five sections:

• Heading
• List of representative field operations
• List of materials and services used
• Operations and interest tabulations
• Overhead costs including real estate taxes and opportunity­ charges

The budgets are presented in a worksheet format with a “Your Estimate’’ column for recording cost modifications.

Cyclic Peptides Containing Tryptophan And Arginine As Src Kinase Inhibitors, Amir Nasrolahi Shirazi, Rakesh Kumar Tiwari, Alex Brown, Dindyal Mandal, Gongqin Sun, Keykavous Parang

Cell and Molecular Biology Faculty Publications

A number of cyclic and linear peptides containing various combinations of amino acids were evaluated for their Src kinase inhibitory potency. Among all the peptides, cyclic decapeptide C[RW]₅ containing alternative arginine (R) and tryptophan (W) residues was found to be the most potent Src kinase inhibitor. C[RW]₅ showed higher inhibitory activity (IC₅₀ = 2.8 μM) than C[KW]₅, L(KW)₅, C[RW]₄, and C[RW]₃ with IC₅₀ values of 46.9, 69.1, 21.5, and 25.0 μM, respectively, as determined in a fluorescence intensity-based assay. Thus, the cyclic nature, the presence of arginine, ring size, …

The Scientist, Spring 2013, San Jose State University, College Of Science

The Scientist (College of Science)

No abstract provided.

University Update - September 6, 2013, Academic Affairs

University Updates & Communications from the University President

Included in this update are:

• Institutional Priorities
• Investment in Human Resources
• Financial Strength
• Strengthening Student Success
• Strengthening Academic Excellence
• Hunger Action Month

Plant-Symbiotic Fungi As Chemical Engineers: Multi-Genome Analysis Of The Clavicipitaceae Reveals Dynamics Of Alkaloid Loci, Christopher L. Schardl, Carolyn A. Young, Uljana Hesse, Stefan G. Amyotte, Kalina Andreeva, Patrick J. Calie, Damien J. Fleetwood, David C. Haws, Neil Moore, Birgitt Oeser, Daniel G. Panaccione, Kathryn K. Schweri, Christine R. Voisey, Mark L. Farman, Jerzy W. Jaromczyk, Bruce A. Roe, Donal M. O'Sullivan, Barry Scott, Paul Tudzynski, Zhiqiang An, Elissaveta G. Arnaoudova, Charles T. Bullock, Nikki D. Charlton, Li Chen, Murray Cox, Randy D. Dinkins, Simona Florea, Anar K. Khan, Eckhard Leistner, Adrian Leuchtmann, Chunjie Li, Jinge Liu, Jinze Liu, Miao Liu, Wade Mace, Caroline Machado, Ella V. Wilson, Jennifer L. Wiseman, Ruriko Yoshida, Zheng Zheng

Faculty & Staff Scholarship

The fungal family Clavicipitaceae includes plant symbionts and parasites that produce several psychoactive and bioprotective alkaloids. The family includes grass symbionts in the epichloae clade (Epichloë and Neotyphodium species), which are extraordinarily diverse both in their host interactions and in their alkaloid profiles. Epichloae produce alkaloids of four distinct classes, all of which deter insects, and some—including the infamous ergot alkaloids—have potent effects on mammals. The exceptional chemotypic diversity of the epichloae may relate to their broad range of host interactions, whereby some are pathogenic and contagious, others are mutualistic and vertically transmitted (seed-borne), and still others vary in pathogenic …

Genomic Insights Into Salt Adaptation In A Desert Poplar, Tao Ma, Junyi Wang, Gongke Zhou, Zhen Yue, Quanjun Hu, Yan Chen, Bingbing Liu, Qiang Qiu, Zhuo Wang, Jian Zhang, Kun Wang, Dechun Jiang, Caiyun Gou, Lili Yu, Dongliang Zhan, Ran Zhou, Wenchun Luo, Hui Ma, Yongzhi Yang, Shengkai Pan, Dongming Fang, Yandan Luo, Xia Wang, Gaini Wang, Juan Wang, Qian Wang, Xu Lu, Zhe Chen, Jinchao Liu, Yao Lu, Ye Yin, Huanming Yang, Richard J. Abbott, Yuxia Wu, Dongshi Wan, Jia Li, Tongming Yin, Martin Lascoux, Stephen P. Difazio, Gerald A. Tuskan, Jun Wang, Jianquan Liu

Faculty & Staff Scholarship

Despite the high economic and ecological importance of forests, our knowledge of the genomic evolution of trees under salt stress remains very limited. Here we report the genome sequence of the desert poplar, Populus euphratica, which exhibits high tolerance to salt stress. Its genome is very similar and collinear to that of the closely related mesophytic congener, P. trichocarpa. However, we find that several gene families likely to be involved in tolerance to salt stress contain significantly more gene copies within the P. euphratica lineage. Furthermore, genes showing evidence of positive selection are significantly enriched in functional categories …

Creation Of An Open-Access, Mutation-Defined Fibroblast Resource For Neurological Disease Research, Selina Wray, Matthew Self, Ninds Parkinson's Disease Ipsc Consortium, Ninds Huntington's Disease Ipsc Consortium, Ninds Als Ipsc Consortium, Patrick A. Lewis, Jan-Willem Taanman, Natalie S. Ryan, Colin J. Mahoney, Yuying Liang, Michael J. Devine, Una-Marie Sheerin, Henry Houlden, Huw R. Morris, Daniel Healy, Jose-Felix Marti-Masso, Elisavet Preza, Suzanne Barker, Margret Sutherland, Roderick A. Corriveau, Michael D'Andrea, Anthony H V Schapira, Ryan J. Uitti, Jaroslaw Slawek, Ludwig Gutmann, Bradley F. Boeve, Kevin Boylan, A Jon Stoessl, Owne A. Ross, Nicholas J. Maragakis, Serge E. Przedborski, Steven Finkbeiner, Jeffery D. Rothstein, Zbigniew K. Wszolek, Martin N. Rossor, John Hardy

Faculty & Staff Scholarship

Our understanding of the molecular mechanisms of many neurological disorders has been greatly enhanced by the discovery of mutations in genes linked to familial forms of these diseases. These have facilitated the generation of cell and animal models that can be used to understand the underlying molecular pathology. Recently, there has been a surge of interest in the use of patient-derived cells, due to the development of induced pluripotent stem cells and their subsequent differentiation into neurons and glia. Access to patient cell lines carrying the relevant mutations is a limiting factor for many centres wishing to pursue this research. …

Occupational Therapy Program 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Cardiovascular Sonography Tampa 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.

Predictable Materiality: A Need For Common Criteria Governing The Disclosure Of Clinical Trial Results By Publicity-Traded Pharmaceutical Companies, Katherine Cohen, Joseph W. Cormier, Mahnu V. Davar

Journal of Contemporary Health Law & Policy (1985-2015)

No abstract provided.

"Rethinking" Embryo Disposition Upon Divorce, Michael T. Flannery

Journal of Contemporary Health Law & Policy (1985-2015)

No abstract provided.

Synthesis And Evaluation Of Cytotoxic Activity Of Substituted N-(9-Oxo-9h-Xanthen-4-Yl)Benzenesulfonamides, Somayeh Motavallizadeh, Asal Asal Fallah-Taftia, Saeedeh Maleki, Amir Nasrolahi Shirazi, Mahboobeh Pordeli, Maliheh Safavi, Sussan Kabudanian Ardestani, Shaaban Asd, Rakesh Tiwari, Donghoon Oh, Abbas Shafiee, Alireza Foroumadi, Keykavous Parang, Tahmineh Akbarzadeh

Biomedical and Pharmaceutical Sciences Faculty Publications

Several novel N-(9-oxo-9H-xanthen-4-yl)benzenesulfonamides derivatives were prepared as potential antiproliferative agents. The in vitro antiproliferative activity of the synthesized compounds was investigated against a panel of tumor cell lines including breast cancer cell lines (MDA-MB-231, T-47D) and neuroblastoma cell line (SK-N-MC) using MTT colorimetric assay. Etoposide, a well-known anticancer drug, was used as a positive standard drug. Among synthesized compounds, 4-methoxy-N-(9-oxo-9H-xanthen-4-yl)benzenesulfonamide (5i) showed the highest antiproliferative activity against MDA-MB-231, T-47D, and SK-N-MC cells. Furthermore, pentafluoro derivatives 5a and 6a exhibited higher antiproliferative activity than doxorubicin against human leukemia cell line (CCRF-CEM) and breast adenocarcinoma …

Surface Decorated Gold Nanoparticles By Linear And Cyclic Peptides As Molecular Transporters, Amir Nasrolahi Shirazi, Rakesh Kumar Tiwari, Donghoon Oh, Brian Sullivan, Kellen Mccaffrey, Dindyal Mandal, Keykavous Parang

Biomedical and Pharmaceutical Sciences Faculty Publications

Gold nanoparticles (AuNPs) were synthesized in situ in a green and rapid method from the reaction of reducing linear and cyclic peptides containing tryptophan and lysine residues, (KW)₅ and cyclic [KW]₅, with an aqueous solution of HAuCl₄ and were evaluated as cellular nanodrug delivery systems. The cyclic or linear nature of the peptide was found to determine the morphology and size of the formed peptide-AuNPs and their in vitro molecular transporting efficiency. While cyclic [KW]₅-AuNPs formed sponge-like agglomerates, linear (KW)₅-AuNPs demonstrated ball-shaped structures. A comparative flow cytometry study showed that the cellular …

Madison Magazine, Vol. 36, No. 1, Winter 2013 Full Issue

Madison Magazine

No abstract provided.

The Relationship Between Collegiate Band Members’ Preferences Of Teacher Interpersonal Behavior And Perceived Self-Efficacy, Natalie Steele Royston

Research & Issues in Music Education

The purposes of this study were to describe collegiate band members’ preferred teacher interpersonal behaviors and perceptions of self-efficacy based on the gender, year in college, instrument, and major and to measure the relationship between preferences of interpersonal teacher behavior and self-efficacy scores. The sample (N = 1,020) was composed of band members at 12 universities from different regions of the United States. Participants completed the Teacher Interaction Preference Questionnaire (TIPQ) and the Self-Efficacy Questionnaire (SEQ). Descriptive statistics were calculated for each of the questionnaires. Results for the TIPQ showed that all sub-groups most preferred the dominant-cooperative behaviors, followed …

A Portrait Of The Insider Trader As A Woman, Joan Macleod Heminway

Book Chapters

No abstract provided.

Ovaries, Testicles, And Uteruses, Oh My! Regulating Reproductive Tissue Transplants, Valarie K. Blake

Scholarly Works

This article will explore key regulatory and ethical challenges presented by reproductive tissue transplants (RTTs) as they are currently developing, recognizing that additional issues may reveal themselves as the technologies progress. Part I of this article will begin with a discussion of the current status of the technology, including the results and status of animal and human experiments for all three types of transplants. Part II will explore the demand for RTTs — who might consider such a transplant and why RTTS might be considered by some patients as more favorable than other reproductive options. Part III will explore the …

Community And Ecosystem Effects Of Buffelgrass (Pennisetum Ciliare) And Nitrogen Deposition In The Sonoran Desert, Kelly G. Lyons, B. G. Maldonado-Leal, G. Owen

Biology Faculty Research

Buffelgrass is a non-indigenous, invasive, C₄ grass that was introduced throughout much of southern Texas, the Southwestern United States, and northern and central Mexico to improve degraded rangelands. The successful introduction and spread of buffelgrass follows a trajectory similar to that of other invasive C₄ grasses in arid and semiarid ecosystems. In the Plains of Sonora of the Sonoran Desert (Mexico) buffelgrass is favored by widespread removal of native vegetation and seeding, but, why, following initial introduction, the species persists remains unclear. In this study, we addressed two concerns associated with buffelgrass invasion in the Plains of Sonora. …

Broadly Applicable Methodology For The Rapid And Dosable Small Molecule-Mediated Regulation Of Transcription Factors In Human Cells, M. D. Shoulders, L. M. Ryno, Christina B. Cooley, J. W. Kelly, R. L. Wiseman

Chemistry Faculty Research

Direct and selective small molecule control of transcription factor activity is an appealing avenue for elucidating the cell biology mediated by transcriptional programs. However, pharmacologic tools to modulate transcription factor activity are scarce because transcription factors are not readily amenable to small molecule-mediated regulation. Moreover, existing genetic approaches to regulate transcription factors often lead to high nonphysiologic levels of transcriptional activation that significantly impair our ability to understand the functional implications of transcription factor activity. Herein, we demonstrate that small molecule-mediated conformational control of protein degradation is a generally applicable, chemical biological methodology to obtain small molecule-regulated transcription factors that …

A Macrophysiological Analysis Of Energetic Constraints On Geographic Range Size In Mammals, Salvatore J. Agosta, Joseph Bernado, Gerardo Ceballos, Michael A. Steele

Biology Publications

Physiological processes are essential for understanding the distribution and abundance of organisms, and recently, with widespread attention to climate change, physiology has been ushered back to the forefront of ecological thinking. We present a macrophysiological analysis of the energetics of geographic range size using combined data on body size, basal metabolic rate (BMR), phylogeny and range properties for 574 species of mammals. We propose three mechanisms by which interspecific variation in BMR should relate positively to geographic range size: (i) Thermal Plasticity Hypothesis, (ii) Activity Levels/Dispersal Hypothesis, and (iii) Energy Constraint Hypothesis. Although each mechanism predicts a positive correlation between …

Characterization And Generation Of Male Courtship Song In Cotesia Congregata (Hymenoptera: Braconidae), Justin P. Bredlau, Yasha J. Mohajer, Timothy M. Cameron, Karen M. Hester, Michael L. Fine

Biology Publications

Background

Male parasitic wasps attract females with a courtship song produced by rapid wing fanning. Songs have been described for several parasitic wasp species; however, beyond association with wing fanning, the mechanism of sound generation has not been examined. We characterized the male courtship song of Cotesia congregata (Hymenoptera: Braconidae) and investigated the biomechanics of sound production.

Methods and Principal Findings

Courtship songs were recorded using high-speed videography (2,000 fps) and audio recordings. The song consists of a long duration amplitude-modulated “buzz” followed by a series of pulsatile higher amplitude “boings,” each decaying into a terminal buzz followed by a …

When Data Curation Isn’T: A Redefinition For Liberal Arts Universities, Megan Toups, Michael J. Hughes

Library Faculty Research

Data curation is one way that libraries are extending traditional services to meet the changing needs of patrons. Requirements from research funders have placed increased pressure on grant recipients to create Data Management Plans and to securely store raw data. Research universities have stepped up to provide comprehensive data support services. Despite discrepancies in funding and staff, smaller institutions can similarly provide robust services by focusing on their strengths, such as interdepartmental collaboration, flexibility, and rapid turnaround time. This article details how librarians at Trinity University adapted the larger practice of curation to meet local data management needs.

Training Students At Small & Medium Sized Colleges In Information Literacy (Chapter Excerpt), D. Russell Bailey, Julie Decesare

Library Faculty and Staff papers

No abstract provided.

Fairness And Antitrust Reconsidered: An Evolutionary Perspective, Thomas J. Horton

McGeorge Law Review

No abstract provided.

State Interests And The Duration Of Abortion Rights, Randy Beck

McGeorge Law Review

No abstract provided.

Endangered And Threatened Wildlife And Plants; Designation Of Critical Habitat For Gunnison Sage-Grouse; Proposed Rule, Patty Gelatt

United States Fish and Wildlife Service: Publications

We, the U.S. Fish and Wildlife Service, propose to designate critical habitat for the Gunnison sagegrouse (Centrocercus minimus) under the Endangered Species Act of 1973, as amended (Act). If we finalize this rule as proposed, it would extend the Act’s protections to this species’ critical habitat. The effect of this regulation is to designate critical habitat for the Gunnison sage-grouse under the Act. In total, approximately 689,675 hectares (ha) (1,704,227 acres (ac)) are being proposed for designation as critical habitat in Chaffee, Delta, Dolores, Gunnison, Hinsdale, Mesa, Montrose, Ouray, Saguache, and San Miguel Counties in Colorado, and in …

50 Cfr Part 17: Endangered And Threatened Wildlife And Plants; Endangered Status For Gunnison Sage-Grouse; Proposed Rule, Patty Gelatt

United States Fish and Wildlife Service: Publications

We, the U.S. Fish and Wildlife Service, propose to list the Gunnison sage-grouse (Centrocercus minimus) as endangered under the Endangered Species Act of 1973, as amended (Act). The effect of this regulation would be to add the Gunnison sage-grouse to the Lists of Endangered and Threatened Wildlife under the Act.

Review Of Captive-Reared Mallard Regulations On Shooting Preserves- Final Report

United States Fish and Wildlife Service: Publications

As numbers of wild ducks declined and hunting opportunities became more restricted in the mid- 1980s, interest in shooting captive-reared mallards on shooting preserves increased dramatically. In 1985, the U. S. Fish and Wildlife Service (Service) received a series of letters regarding the interpretation of regulations in 50 CFR 21.13 and the practice in Maryland of releasing captive-reared mallards in a freeflying condition on their State-licensed shooting preserves. Prior to this time, shooting preserves released flighted mallards from towers as a general practice to be shot immediately after release and maintained tighter control to prevent these birds from escaping to …