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2013

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Phylogenetic Analyses Of Tolpis Adans. (Asteraceae) Reveal Patterns Of Adaptive Radiation, Multiple Colonization And Interspecific Hybridization, Michael Gruenstaeudl, Arnoldo Santos-Guerra, Robert K. Jansen Jan 2013

Phylogenetic Analyses Of Tolpis Adans. (Asteraceae) Reveal Patterns Of Adaptive Radiation, Multiple Colonization And Interspecific Hybridization, Michael Gruenstaeudl, Arnoldo Santos-Guerra, Robert K. Jansen

Biological Sciences Faculty Publications

The plant genus Tolpis (Asteraceae) has been the subject of several investigations on the evolution of oceanic island plants. Its insular species were utilized in studies of artificial hybrid fertility, testing the validity of Baker’s law, the application of DNA barcodes, and the phylogenetic utility of inter-simple sequence repeat markers. Despite this considerable interest in Tolpis, little is known about its phylogenetic history. Past investigations were unable to resolve most of the interspecific relationships, especially within the Canary Islands, where the genus is particularly diverse. Incomplete taxon sampling, the use of ambiguous outgroups and the limited utility of slowly evolving …


Phenotypic And Genotypic Characterization Of Escherichia Coli Isolated From Untreated Surface Waters, Kai Hung, Steven Daniel, Kristopher Janezic, Blake Ferry, Eric Hendricks, Brian Janiga, Tiffany Johnson, Samantha Murphy, Morgan Roberts, Sarah Scott, Alexandra Theisen Jan 2013

Phenotypic And Genotypic Characterization Of Escherichia Coli Isolated From Untreated Surface Waters, Kai Hung, Steven Daniel, Kristopher Janezic, Blake Ferry, Eric Hendricks, Brian Janiga, Tiffany Johnson, Samantha Murphy, Morgan Roberts, Sarah Scott, Alexandra Theisen

Faculty Research & Creative Activity

A common member of the intestinal microbiota in humans and animals is Escherichia coli. Based on the presence of virulence factors, E. coli can be potentially pathogenic. The focus of this study was to isolate E. coli from untreated surface waters (37 sites) in Illinois and Missouri and determine phenotypic and genotypic diversity among isolates. Water samples positive for fecal coliforms based on the Colisure® test were streaked directly onto Eosin Methylene Blue (EMB) agar (37°C) or transferred to EC broth (44.5°C). EC broth cultures producing gas were then streaked onto EMB agar. Forty-five isolates were identified as E. coli …


The Spatial Distribution Of The Japanese Beetle, Popillia Japonica, In Soybean Fields, Stacey Sara, Emily Mccallen, Paul Switzer Jan 2013

The Spatial Distribution Of The Japanese Beetle, Popillia Japonica, In Soybean Fields, Stacey Sara, Emily Mccallen, Paul Switzer

Faculty Research & Creative Activity

The Japanese beetle, Popillia japonica Newman (Coleoptera: Scarabaeidae), is a serious pest of many agricultural and horticultural plants. Relatively little research has investigated the distributions of Japanese beetles in agricultural fields, and this lack of information makes pest management more difficult. In the present study, the spatial distribution of Japanese beetles in soybean fields was examined. Specifically, how the distribution and abundance of beetles was affected by distance from an edge, edge direction, and edge type was examined. An edge effect for density was discovered; beetle numbers decreased significantly with increasing distance from the field edge. The east and south …


Improved Tolerance To Salt And Water Stress In Drosophila Melanogaster Cells Conferred By Late Embryogenesis Abundant Protein, Matthew R. Marunde, Dilini A. Samarajeewa, John Anderson, Shumin Li, Steven C. Hand, Michael A. Menze Jan 2013

Improved Tolerance To Salt And Water Stress In Drosophila Melanogaster Cells Conferred By Late Embryogenesis Abundant Protein, Matthew R. Marunde, Dilini A. Samarajeewa, John Anderson, Shumin Li, Steven C. Hand, Michael A. Menze

Faculty Research & Creative Activity

Mechanisms that govern anhydrobiosis involve the accumulation of highly hydrophilic macromolecules, such as late embryogenesis abundant (LEA) proteins. Group 1 LEA proteins comprised of 181 (AfLEA1.1) and 197 (AfLEA1.3) amino acids were cloned from embryos of Artemia franciscana and expressed in Drosophila melanogaster cells (Kc167). Confocal microscopy revealed a construct composed of green fluorescence protein (GFP) and AfLEA1.3 accumulates in the mitochondria (AfLEA1.3-GFP), while AfLEA1.1-GFP was found in the cytoplasm. In the presence of mixed substrates, oxygen consumption was statistically identical for permeabilized Kc167 control and Kc167-AfLEA1.3 cells. Acute titrations of permeabilized cells with NaCl up to 500 mM led …


Gulf-Wide Decreases In The Size Of Large Coastal Sharks Documented By Generations Of Fishermen, Sean P. Powers, F. Joel Frodrie, Steven B. Scyphers, J. Marcus Drymon, Robert L. Shipp, Gregory W. Stunz Jan 2013

Gulf-Wide Decreases In The Size Of Large Coastal Sharks Documented By Generations Of Fishermen, Sean P. Powers, F. Joel Frodrie, Steven B. Scyphers, J. Marcus Drymon, Robert L. Shipp, Gregory W. Stunz

University Faculty and Staff Publications

Large sharks are top predators in most coastal and marine ecosystems throughout the world, and evidence of their reduced prominence in marine ecosystems has been a serious concern for fisheries and ecosystem management. Unfortunately, quantitative data to document the extent, timing, and consequences of changes in shark populations are scarce, thwarting examination of long-term (decadal, century) trends, and reconstructions based on incomplete data sets have been the subject of debate. Absence of quantitative descriptors of past ecological conditions is a generic problem facing many fields of science but is particularly troublesome for fisheries scientists who must develop specific targets for …


Virulence Of Xanthomonas Translucens Pv. Poae Isolated From Poa Annua, Arielle Chaves, Nathaniel Mitkowski Jan 2013

Virulence Of Xanthomonas Translucens Pv. Poae Isolated From Poa Annua, Arielle Chaves, Nathaniel Mitkowski

Plant Sciences and Entomology Faculty Publications

Bacterial wilt is a vascular wilt disease caused by Xanthomonas translucens pv. poae that infects Poa annua, a grass that is commonly found on golf course greens throughout the world. Bacterial wilt causes symptoms of etiolation, wilting, and foliar necrosis. The damage is most prevalent during the summer and the pathogen can kill turf under conditions optimal for disease development. Fifteen isolates of X. translucens pv. poae were collected from northern regions in the United States and tested for virulence against P. annua. All 15 isolates were pathogenic on P. annua, but demonstrated variable levels of …


Beyond Humanization And De-Immunization: Tolerization As A Method For Reducing The Immunogenicity Of Biologics, Anne S. De Groot, Frances Terry, Leslie Cousens, William Martin Jan 2013

Beyond Humanization And De-Immunization: Tolerization As A Method For Reducing The Immunogenicity Of Biologics, Anne S. De Groot, Frances Terry, Leslie Cousens, William Martin

Institute for Immunology and Informatics Faculty Publications

Immune responses to some monoclonal antibodies (mAbs) and biologic proteins interfere with their efficacy due to the development of anti-drug antibodies (ADA). In the case of mAbs, most ADA target ‘foreign’ sequences present in the complementarity determining regions (CDRs). Humanization of the mAb sequence is one approach that has been used to render biologics less foreign to the human immune system. However, fully human mAbs can also drive immunogenicity. De-immunization (removing epitopes) has been used to reduce biologic protein immunogenicity. Here, we discuss a third approach to reducing the immunogenicity of biologics: introduction of Treg epitopes that stimulate …


Immunopathogenesis Versus Protection In Dengue Virus Infections, Alan L. Rothman, Carey L. Medin, Heather Friberg, Jeffery R. Currier Jan 2013

Immunopathogenesis Versus Protection In Dengue Virus Infections, Alan L. Rothman, Carey L. Medin, Heather Friberg, Jeffery R. Currier

Institute for Immunology and Informatics Faculty Publications

Dengue viruses (DENV) are mosquito-borne viruses that cause significant morbidity. The existence of four serotypes of DENV with partial immunologic cross-reactivity creates the opportunity for individuals to experience multiple acute DENV infections over the course of their lifetimes. Research over the past several years has revealed complex interactions between DENV and the human innate and adaptive immune systems that can have either beneficial or detrimental influences on the outcome of infection. Further studies that seek to distinguish protective from pathological immune responses in the context of natural DENV infection as well as clinical trials of candidate DENV vaccines have an …


Tregitope Peptides: The Active Pharmaceutical Ingredient Of Ivig?, Anne S. De Groot, Leslie Cousens, Federico Mingozzi, William Martin Jan 2013

Tregitope Peptides: The Active Pharmaceutical Ingredient Of Ivig?, Anne S. De Groot, Leslie Cousens, Federico Mingozzi, William Martin

Institute for Immunology and Informatics Faculty Publications

Five years ago, we reported the identification and characterization of several regulatory T-cell epitopes (now called Tregitopes) that were discovered in the heavy and light chains of IgG (De Groot et al. Blood, 2008). When added ex vivo to human PBMCs, these Tregitopes activated regulatory T cells (Tregs), increased expression of the transcription factor FoxP3, and induced IL- 10 expression in CD4+ T cells. We have now shown that coadministration of the Tregitopes in vivo, in a number of different murine models of autoimmune disease, can suppress immune responses to antigen in an antigen-specific manner, and that this response is …


Report From The Field - Overview Of The Sixth Annual Vaccine Renaissance Conference, Denice Spero, Lauren Levitz, Anne S. De Groot Jan 2013

Report From The Field - Overview Of The Sixth Annual Vaccine Renaissance Conference, Denice Spero, Lauren Levitz, Anne S. De Groot

Institute for Immunology and Informatics Faculty Publications

The Sixth Annual Vaccine Renaissance Conference, hosted by the Institute for Immunology and Informatics (iCubed) at the University of Rhode Island (URI), took place on October 15–17, 2012. This conference provides a forum for the review of current progress in the discovery and development of vaccines, and creates an environment for the exchange of ideas. Dr. Joel McCleary opened the conference with a warning about the importance of preparing for well-defined biowarfare threats, including tularemia and Staphylococcal enterotoxin B. Following the keynote address, sessions explored biodefense and preparation for pandemic and biowarfare threats; vaccines for emerging and re-emerging neglected …


Low Immunogenicity Predicted For Emerging Avian-Origin H7n9, Anne S. De Groot, Matthew Ardito, Frances Terry, Lauren Levitz, Ted Ross, Leonard Moise, William Martin Jan 2013

Low Immunogenicity Predicted For Emerging Avian-Origin H7n9, Anne S. De Groot, Matthew Ardito, Frances Terry, Lauren Levitz, Ted Ross, Leonard Moise, William Martin

Institute for Immunology and Informatics Faculty Publications

A new avian-origin influenza virus emerged near Shanghai in February 2013, and by the beginning of May it had caused over 130 human infections and 36 deaths. Human-to-human transmission of avian-origin H7N9 influenza A has been limited to a few family clusters, but the high mortality rate (27%) associated with human infection has raised concern about the potential for this virus to become a significant human pathogen. European, American, and Asian vaccine companies have already initiated the process of cloning H7 antigens such as hemagglutinin (HA) into standardized vaccine production vehicles. Unfortunately, previous H7 HA-containing vaccines have been poorly immunogenic. …


Virginia Commonwealth University Undergraduate Bulletin Courses [2013], Virginia Commonwealth University Jan 2013

Virginia Commonwealth University Undergraduate Bulletin Courses [2013], Virginia Commonwealth University

VCU Bulletins

Listing of undergraduate courses for 2013-2014.


Faculty Promotion And Tenure Recipients, 2013, University Of Arkansas, Fayetteville. Libraries, University Of Arkansas, Fayetteville. Provost And Vice Chancellor For Academic Affairs, University Of Arkansas, Fayetteville. Office Of The Chancellor Jan 2013

Faculty Promotion And Tenure Recipients, 2013, University Of Arkansas, Fayetteville. Libraries, University Of Arkansas, Fayetteville. Provost And Vice Chancellor For Academic Affairs, University Of Arkansas, Fayetteville. Office Of The Chancellor

Faculty Promotion and Tenure Reception

Event was sponsored by Chancellor and Provost


Arkansas Women's Cross Country, 2013, University Of Arkansas, Fayetteville. Athletics Media Relations Jan 2013

Arkansas Women's Cross Country, 2013, University Of Arkansas, Fayetteville. Athletics Media Relations

Arkansas Women's Cross Country

No abstract provided.


Dynamic Energy Federalism, Hannah J. Wiseman, Hari M. Osofsky Jan 2013

Dynamic Energy Federalism, Hannah J. Wiseman, Hari M. Osofsky

Scholarly Publications

United States energy law and the scholarship analyzing it are deeply fragmented. Each source of energy has a distinct legal regime, and limited federal regulation in some areas has resulted in divergent state and local approaches to regulation. Much of the existing energy law literature reflects these substantive and structural divisions, and focuses on particular aspects of the energy system and associated federalism disputes. However, in order to meet modern energy challenges—such as reducing risks from deepwater drilling and hydraulic fracturing, maintaining the reliability of the electricity grid in this period of rapid technological change, and producing cleaner energy—we need …


Team-Based Learning In Medical Education, Kathryn W. Smith Jan 2013

Team-Based Learning In Medical Education, Kathryn W. Smith

Theses

The main purpose of this study is to determine if the use of Team-Based Learning as a method of instruction is more effective in terms of student achievement than the traditional lecture method in an anatomy course at a state university medical school. Student scores from two academic years (2011-2012 academic year and the 2012-2013 academic year) for the average of four exams were analyzed using an independent sample t-test to determine if the intervention of Team-Based Learning made a difference on student achievement. Students were paired from each academic year based on final entering MCAT score, age at matriculation, …


Biocompatibility Of Magnesium-Based Biomaterials For Airway Stent Applications, Sara Dolly Tatum Jan 2013

Biocompatibility Of Magnesium-Based Biomaterials For Airway Stent Applications, Sara Dolly Tatum

Theses

Tracheomalacia, stenosis and other traumatic airway injuries (e.g., obstructive tracheobronchial tumors) often require airway stenting. Traditional polymeric stents are prone to cause infection, do not ‘grow’ with a child and often require surgical removal. Therefore, resorbable biometallics are ideal materials for tracheal stent devices. Magnesium (Mg) is an attractive material because of its biocompatibility, abundance within the human body, and intrinsic corrosive nature can be overcome via alloying elements. We hypothesize that resorbable magnesium-based materials can be utilized for the development of tracheal stents. The objective of the present study was to determine cytocompatibility of Mg alloys with fully differentiated …


Production Of Canola As A Biofuel Feedstock In The Piedmont Region Of North Carolina, Matthew Rhyan Miller Jan 2013

Production Of Canola As A Biofuel Feedstock In The Piedmont Region Of North Carolina, Matthew Rhyan Miller

Theses

Canola in the past and present has been evaluated as a domestic fuel source and a means to stimulate rural economic development. In order to ease the transition of the economy in North Carolina new rotational crops can be looked upon as sources of additional revenue. Canola Brassica napus (L.) production was evaluated for cultivation in a Piedmont soil (Mecklenburg Sandy Clay Loam) at NC A&T State University research farm located in Greensboro, NC (Guilford County). The experiment was conducted using a split plot design with main plot factor cultivar (Virginia and DKW 46-15) and subplot factor fertilizer: (N-P2O5-K2O) in …


Synthesis Of Pcl/Keratin Composite Nanofibers For Nerve Repair Application, Angela Michelle Edwards Jan 2013

Synthesis Of Pcl/Keratin Composite Nanofibers For Nerve Repair Application, Angela Michelle Edwards

Theses

In the past decade, a wide variety of biomaterials comprised of both synthetic and natural polymers have been used to promote restoration of injured peripheral nerves. Despite making advances, none have matched performance of autographs, a gold standard in nerve repair. Mammalian-derived, protein-based conduits have shown good tissue biocompatibility and safe degradation products, but are mechanically fragile. Synthetic materials such as Polycaprolactone (PCL) typically have advantage of suitable mechanical properties and fine degradation rate tunability, but lack cell recognition signaling. Recent studies have shown that keratin promotes nerve cell attachment, differentiation and growth, but alone, it cannot be used as …


The Effectiveness Of Small Scale Photovoltaic (Pv) Systems Design And Cost Analysis Simulation On Saudi Arabian Economy, Faris Abdullah Almansour Jan 2013

The Effectiveness Of Small Scale Photovoltaic (Pv) Systems Design And Cost Analysis Simulation On Saudi Arabian Economy, Faris Abdullah Almansour

Theses

The advantages of Renewable Energy Sources (RES) are much more than the disadvantages, RES such as solar, wind energy, biomass, and geothermal, which can be used for generating distributed power but cannot directly replace the existing electric energy grid technologies. The latter are far too well established to abandon, while the new RES technologies are not sufficiently developed to meet the total energy demand. Therefore, it is sensible to gradually infuse RES into existing grids and transform the system over time Saudi Arabia (SA) is a semi-developed nation with a population of over twenty nine million people. It is the …


Synthesis And Characterization Of Boronic Acid Chalcones As Potential Cancer Chemoprevention Drug Candidates, Davia Lauren Mckoy Jan 2013

Synthesis And Characterization Of Boronic Acid Chalcones As Potential Cancer Chemoprevention Drug Candidates, Davia Lauren Mckoy

Theses

Carcinogenesis is the transformation of a normal cell into a cancerous cell. Cancer chemoprevention is the use of natural and synthetic compounds to stop carcinogenesis. These compounds have been labeled chemopreventives and they take advantage of the human body's natural defenses to stop carcinogenesis. Chalcones have demonstrated antibacterial, antifungal, antitumor, and anti-inflammatory properties. In this project, chalcones and their derivatives are synthesized with the goal to be used as possible chemopreventives. We believe that when tested on cancer cell lines, the boronic acid derivative will show greater chemopreventive activity because of the boronic acid's increased bioavailability. We have synthesized and …


Synthesis Of Biodiesel From Animal Fat And Polymerization Of Glycerin, Zixu Zhang Jan 2013

Synthesis Of Biodiesel From Animal Fat And Polymerization Of Glycerin, Zixu Zhang

Theses

Biodiesel was synthesized using raw beef fat using esterification and transesterification reaction. The obtained biodiesel-glycerin mixture was tested using Fourier transform infrared resonance (FT-IR) and compared with the FT-IR of raw beef fat, glycerin, biodiesel made from vegetable oil and commercial biodiesel. The FT-IR spectrum of the synthesized biodiesel was identical to that of biodiesel made from vegetable oil. Poly-glycerin was synthesized from glycerin by water elimination reaction, where solid NaOH was used as a catalyst under a stream of nitrogen gas. The water-elimination reaction obeys the "N-1" rule. "N-1" is the degree of polymerization and "N" is the number …


Application Of Adaptive Extended Kalman Filtering Scheme To Improve The Efficiency Of A Groundwater Contaminant Transport Model, Elvis Boamah Addai Jan 2013

Application Of Adaptive Extended Kalman Filtering Scheme To Improve The Efficiency Of A Groundwater Contaminant Transport Model, Elvis Boamah Addai

Theses

Pollution of groundwater can be harmful to the environment. The use of subsurface contaminant transport models, combined with stochastic data assimilation schemes, can give on-target predictions of contaminant transport to enhance the reliability of risk assessment in the area of environmental remediation. Observation data are required to guide the deterministic system model to assimilate the true state of the contaminant. Modeling the behavior of contaminant in groundwater is imperative in predicting the fate of the pollutant, in risk assessment, and as a preceding step of the remission process. In this study a two-dimensional transport model with advection and dispersion is …


Alzheimer's Disease Literacy In The African American Community, Angel Mckenzie Watson Jan 2013

Alzheimer's Disease Literacy In The African American Community, Angel Mckenzie Watson

Theses

Alzheimer's disease (AD) is a public health crisis in the African American (AA) community, as evidenced by both increased prevalence and familial risk among African Americans. African Americans are two times as likely to suffer with this disease, are diagnosed later in the disease process, and are considered to have less factual information about AD when compared to their white counterparts. Late diagnosis has been associated with significantly higher dementia-related morbidity and health care costs. Moreover, studies have shown that patients with increased health literacy have better health outcomes. Therefore, we want to assess how well African Americans understand Alzheimer's …


2013-2014 Operating Budget, Morehead State University. Budget & Financial Planning Office. Jan 2013

2013-2014 Operating Budget, Morehead State University. Budget & Financial Planning Office.

Morehead State University Operating Budgets Archive

2013-2014 Operating Budget of Morehead State University.


The Importance Of Female Choice: Evolutionary Perspectives On Constraints, Expressions, And Variations, David Frederick, Tania A. Reynolds, Maryanne L. Fisher Jan 2013

The Importance Of Female Choice: Evolutionary Perspectives On Constraints, Expressions, And Variations, David Frederick, Tania A. Reynolds, Maryanne L. Fisher

Psychology Faculty Books and Book Chapters

This chapter introduces the reader to some of the influential perspectives on female mate choice in human evolutionary biology, including parental investment theory. We then present two key theories in evolutionary psychology that have been applied to understand variations in women’s mating preferences and choices: sexual strategies theory and strategic pluralism theory. Although the importance of female choice has gained widespread acceptance in the biological sciences, the influence that female choice has on mating systems can be limited by many factors, such as control over mating decisions by parents and men’s control over women’s sexuality. Despite these constraints on female …


College Of Dental Medicine Overview 2013, Nova Southeastern University Jan 2013

College Of Dental Medicine Overview 2013, Nova Southeastern University

Health Professions Divisions Course Catalogs and Course Descriptions

No abstract provided.


Table Of Contents Jan 2013

Table Of Contents

Virginia Journal of Science

Table of Contents for Virginia Journal of Science, vol. 64, no. 1 & 2, Spring/Summer 2013


The Beverton–Holt Q-Difference Equation, Martin Bohner, Rotchana Chieochan Jan 2013

The Beverton–Holt Q-Difference Equation, Martin Bohner, Rotchana Chieochan

Mathematics and Statistics Faculty Research & Creative Works

The Beverton–Holt model is a classical population model which has been considered in the literature for the discrete-time case. Its continuous-time analogue is the well-known logistic model. In this paper, we consider a quantum calculus analogue of the Beverton–Holt equation. We use a recently introduced concept of periodic functions in quantum calculus in order to study the existence of periodic solutions of the Beverton–Holt q-difference equation. Moreover, we present proofs of quantum calculus versions of two so-called Cushing–Henson conjectures. © 2013 The Author(s). Published by Taylor & Francis.


Counselling And Storytelling: How Did We Get Here?, Suzanne Jenkins Jan 2013

Counselling And Storytelling: How Did We Get Here?, Suzanne Jenkins

Arts Papers and Journal Articles

We are a species of story-makers and storytellers. Stories are central to our development of self concept and identity and how we distinguish ourselves from others - a process central to our wellbeing. Counselling through storytelling is both an ancient activity and an emerging conceptual model. As an ancient activity it finds its origins in some very old cultural traditions. Australian Aboriginal people have long been telling stories in which they have created a sense of landscape, community and place. These stories hold a significance that stretches from the dawn of time, from the stories of the Dreamtime. The invitation …