Digital Commons Network^™

The Case For An Information-Forcing Regulatory Definition Of “Nanomaterials”, David A. Dana

Pace Environmental Law Review

This Article reviews regulatory attempts to define nanomaterials to date, including the European Commission’s definition. It then sets forth and explains why agencies should adopt what I am calling an information-forcing definition of nanomaterials. Nanomaterials implicate the same informational problem as many other substances or practices that are the subject of political and legal debate: that is, we (the public) know enough to know that there are some risks but not enough to specify and assess those risks. We know risks are posed by some kinds of small-scale materials in some contexts, but not enough is known to define the …

Searching For The Nano-Needle In A Green Haystack: Researching The Environmental, Health, And Safety Ramifications Of Nanotechnology, Taryn L. Rucinski

Pace Environmental Law Review

This Article will attempt to serve as a primer by demystifying the process of how to efficiently locate resources discussing the environmental health and safety (EHS) impacts of nanotechnology in the United States (U.S.). Part I of this Article begins with an examination of basic strategies for conducting research in the EHS nanotech field. Part II focuses on traditional legal resources such as texts, treatises, encyclopedias, as well as law review and journal articles. Part III examines such non-legal resources as reports, scientific studies, internet sites and other current awareness services. This last section is followed by a brief conclusion.

Removal Of Selenium From Fgd Water Streams By A Nonconventional Adsorbent By-Product, Patricia Córdoba, María Eugenia González, Aixa González, Natalia Moreno

World of Coal Ash Proceedings

No abstract provided.

Divine, Scientific, And Phrenological: A Study Of American Religion And Phrenology In The Nineteenth Century, Matthew C. Robinson

Undergraduate Library Research Awards

No abstract provided.

Cinnamon As A Prophylaxis Against Uti In Premenopausal Women, Michelle Iafe

Undergraduate Library Research Awards

No abstract provided.

The Islet Amyloid Polypeptide Hormone Amylin: Its Function, Effects And Uses In Medicine, Spencer W. Roberson

Undergraduate Library Research Awards

No abstract provided.

Executive Committee - Agenda, 4/23/2013, Academic Senate

Academic Senate Agendas

No abstract provided.

The Transcriptional Coactivation Function Of E6-Associated Protein In The Brain: Novel Insights Into The Pathobiology Of Angelman Syndrome, Jimmy El Hokayem

Open Access Dissertations

Angelman syndrome (AS) is a complex genetic disorder that affects the nervous system. AS affects an estimated 1 in 12,000 to 20,000 individuals. Characteristic features of AS includes developmental delay or intellectual disability, severe speech impairment, seizures, small head size (microcephaly), and problems with movement and balance (ataxia). AS individuals usually have microdeletion of the maternal copy of 15q11.2 -15q13 region of chromosome 15. The E6-associated protein, E6AP (an E3 ubiquitin protein ligase enzyme) gene, UBE3A is located in this region and it has been shown that deregulation of E6AP gives rise to AS and neuropathology of autism spectrum disorders …

Glycosylate Derivatives Of Mithramycin, Method Of Preparation And Uses Thereof, Jürgen Rohr, Irfan Baig, Jose Antonio Salas Fernandez, Alfredo Fernandez Brana, Maria Perez Solares

Pharmaceutical Sciences Faculty Patents

The present invention provides compounds characterized by the formula (I), where each of the substituent radicals is described in the specification. The invention also describes the use of said compounds in the treatment of various diseases, including: cancer or tumoral processes in general, Paget's disease, hypercalcaemia, hypercalciuria and neurological diseases (inter alia, Parkinson's, Alzheimer's, Huntington's).

Twenty Winthrop Retirees And 54 Employees Recognized For Service, Winthrop University

Winthrop News 2013

• Twenty Winthrop retirees and 54 university employees were honored for their service at the annual Faculty, Staff, Retirees Awards Ceremony.
• The honored retirees have collectively provided nearly 350 years of service to the state of South Carolina and Winthrop.

Winthrop Recognizes Exceptional Employees During Annual Ceremony, Winthrop University

Winthrop News 2013

• Winthrop University honored 41 employees with presidential citations during the April 23 Faculty, Staff and Retirees Awards Ceremony.
• Retirees Glenn Savage and Lynn Harand were co-recipients of the Mary Spann Richardson Award.
• Associate Professor Kristi Schoepfer received the Faculty Student Life Award.

04-23-2013 Eight Swosu Student Groups Raise $1,000 Plus In Fight Against Cancer, Southwestern Oklahoma State University

THE BARK ARCHIVE 2013

Eight Southwestern Oklahoma State University student organizations raised over $1,000 each for the recent Custer County Relay For Life event held April 19 on the SWOSU campus in Weatherford.

Ua12/2/1 Best Of The Hill Winner's Book 2013, Wku Student Affairs

WKU Administration Documents

Special award edition of the College Heights Herald for best restaurants, businesses and housing in Bowling Green.

Hidden Markov Models For Estimating Animal Mortality From Anthropogenic Hazards, Matthew A. Etterson

United States Environmental Protection Agency: Publications

Carcass searches are a common method for studying the risk of anthropogenic hazards to wildlife, including nontarget poisoning and collisions with anthropogenic structures. Typically, numbers of carcasses found must be corrected for scavenging rates and imperfect detection. Parameters for these processes (scavenging and detection) are often estimated using carcass distribution trials in which researchers place carcasses in the field at known times and locations. In this manuscript I develop a variety of estimators based on multi-event or hidden Markov models for use under different experimental conditions. I apply the estimators to two case studies of avian mortality, one from pesticide …

A Perspective On Multiple Waves Of Influenza Pandemics, Anna Mummert, Howard Weiss, Li-Pong Long, Jose´ M. Amigo´, Xiu-Feng Wan

Mathematics Faculty Research

Background: A striking characteristic of the past four influenza pandemic outbreaks in the United States has been the multiple waves of infections. However, the mechanisms responsible for the multiple waves of influenza or other acute infectious diseases are uncertain. Understanding these mechanisms could provide knowledge for health authorities to develop and implement prevention and control strategies. Materials and Methods: We exhibit five distinct mechanisms, each of which can generate two waves of infections for an acute infectious disease. The first two mechanisms capture changes in virus transmissibility and behavioral changes. The third mechanism involves population heterogeneity (e.g., demography, geography), where …

The Prospector, April 23, 2013, Utep Student Publications

The Prospector

Headline: Art Issue

Method Of Ameliorating Oxidative Stress And Supplementing The Diet, Boyd E. Haley, Niladrl Narayan Gupta

Chemistry Faculty Patents

A method of supplementing a diet and ameliorating oxidative stress in a mammal includes administering a pharmaceutically effective amount of lipid soluble, hydrophobic active compounds having a chemical structure . . .

To see the remainder of this abstract, please download this patent.

Daily Eastern News: April 23, 2013, Eastern Illinois University

April

No abstract provided.

The Hemophore Hasa From Yersinia Pestis (HasaYp) Coordinates Hemin With A Single Residue, Tyr75, And With Minimal Conformational Change, Ritesh Kumar, Scott Lovell, Hirotoshi Matsumura, Kevin P. Battaile, Pierre Moënne-Loccoz, Mario Rivera

Faculty Publications

Hemophores from Serratia marcescens (HasAsm) and Pseudomonas aeruginosa (HasAp) bind hemin between two loops, which harbor the axial ligands H32 and Y75. Hemin binding to the Y75 loop triggers closing of the H32 loop and enables binding of H32. Because Yersinia pestis HasA (HasA yp) presents a Gln at position 32, we determined the structures of apo- and holo-HasAyp. Surprisingly, the Q32 loop in apo-HasA yp is already in the closed conformation, but no residue from the Q32 loop binds hemin in holo-HasAyp. In agreement with the minimal reorganization between the apo- and holo-structures, the hemin on-rate is too fast …

A Perspective On Multiple Waves Of Influenza Pandemics, Anna Mummert, Howard Weiss, Li-Ping Long, José M. Amigó, Xiu-Feng Wan

CVM Publications

BACKGROUND: A striking characteristic of the past four influenza pandemic outbreaks in the United States has been the multiple waves of infections. However, the mechanisms responsible for the multiple waves of influenza or other acute infectious diseases are uncertain. Understanding these mechanisms could provide knowledge for health authorities to develop and implement prevention and control strategies. MATERIALS AND METHODS: We exhibit five distinct mechanisms, each of which can generate two waves of infections for an acute infectious disease. The first two mechanisms capture changes in virus transmissibility and behavioral changes. The third mechanism involves population heterogeneity (e.g., demography, geography), where …

The Advocate, April 23, 2013, Minnesota State University Moorhead

The Advocate

No abstract provided.

Mesobiliverdin Ixα Enhances Rat Pancreatic Islet Yield And Function, Taihei Ito, Dong Chen, Cheng-Wei Tom Chang, Takashi Kenmochi, Tomonori Saito, Satoshi Suzuki, Jon Y. Takemoto

Chemistry and Biochemistry Faculty Publications

The aims of this study were to produce mesobiliverdin IXα, an analog of anti-inflammatory biliverdin IXα, and to test its ability to enhance rat pancreatic islet yield for allograft transplantation into diabetic recipients. Mesobiliverdin IXα was synthesized from phycocyanobilin derived from cyanobacteria, and its identity and purity were analyzed by chromatographic and spectroscopic methods. Mesobiliverdin IXα was a substrate for human NADPH biliverdin reductase. Excised Lewis rat pancreata infused with mesobiliverdin IXα and biliverdin IXα-HCl (1–100 μM) yielded islet equivalents as high as 86.7 and 36.5%, respectively, above those from non-treated controls, and the islets showed a high degree of …

Through The Body: Corporeality, Subjectivity, And Empathy In Contemporary American Art, Elissa Yukiko Weichbrodt

All Theses and Dissertations (ETDs)

This dissertation considers the relationship between embodied experience, subjectivity, and empathy expressed in artworks created and exhibited in New York in the early 1990s and linked with identity politics. I focus on works that represented or evoked bodies and elicited viscerally somatic responses from viewers. As I demonstrate, the multicultural and post-structuralist interpretive frameworks applied to these artworks hinged on implicitly antagonistic notions of subjectivity which undercut the works' affective potential. In particular, such models disregarded the powerful epistemological import of corporeality in favor of discursive constructions. Through three paired case studies, I investigate how these artists engaged with emerging …

Comparative Analysis Of Fungal Genomes Reveals Different Plant Cell Wall Degrading Capacity In Fungi, Zhongtao Zhao, Huiquan Liu, Chenfang Wang, Jin-Rong Xu

Department of Botany and Plant Pathology Faculty Publications

EDITOR'S NOTE

Readers are alerted that there is currently a discussion regarding the use of some of the unpublished genomic data presented in this manuscript. Appropriate editorial action will be taken once this matter is resolved.

Background

Fungi produce a variety of carbohydrate activity enzymes (CAZymes) for the degradation of plant polysaccharide materials to facilitate infection and/or gain nutrition. Identifying and comparing CAZymes from fungi with different nutritional modes or infection mechanisms may provide information for better understanding of their life styles and infection models. To date, over hundreds of fungal genomes are publicly available. However, a systematic comparative analysis …

Collaboration: The Effects Of Joint Agency Training For Both National Guard And Department Of Homeland Security, Benjamin J. Rogers

Purdue Polytechnic Directed Projects

Rogers, Benjamin J. M.S., Purdue University, May 2013. Collaboration: The Effects of

Joint Agency Training for Both National Guard and Department of Homeland Security.

Major Professor: Daniel Lybrook.

Using subject matter experts and responders in the field of incident response, this study

was designed to ascertain whether there is a need for more collaborative training among

both National Guard responders and Department of Homeland Security responders. It

did this by answering the key questions of:

1. What areas within training can be collaborative?

2. What are the effects of joint training on first responders?

3. What training processes can be …

Independent - Apr. 23, 2013, Emily N Haddad

The Independent (1988-present)

No abstract provided.

Divergent Protein Motifs Direct Ef-P Mediated Translational Regulation In Salmonella And Escherichia Coli, Steven J. Hersch, Mengchi Wang, S. Betty Zou, Kyung-Mee Moon, Leonard J. Foster, Michael Ibba, William Wiley Navarre

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Elongation factor P (EF-P) is a universally conserved bacterial translation factor homologous to eukaryotic/archaeal initiation factor 5A. In Salmonella, deletion of the efp gene results in pleiotropic phenotypes, including increased susceptibility to numerous cellular stressors. Only a limited number of proteins are affected by the loss of EF-P, and it has recently been determined that EF-P plays a critical role in rescuing ribosomes stalled at PPP and PPG peptide sequences. Here we present an unbiased in vivo investigation of the specific targets of EF-P by employing stable isotope labeling of amino acids in cell culture (SILAC) to compare the …

If The Shoe Fits…An Artistic Analysis Of The Classic Fairy Talecharacter Cinderella, Corinne Andrew

Honors Theses

No abstract provided.

Patent Protection Of Pharmacologically Active Metabolites: Theoretical And Technological Analysis On The Jurisprudence Of Four Regions, Richard Li-Dar Wang, Pei-Chen Huang

Santa Clara High Technology Law Journal

Active metabolite patents have been instrumental for brandname pharmaceutical companies to maintain their exclusivity even after the drug patents expire. This strategy obstructs market entry of generic medicine and reduces affordable drugs. The authors review jurisprudence from the United States, Europe, India, and Taiwan in search for practical solutions to confront this problem. Given the unique pharmacological value that active metabolites may possess, patent protection for those purified or synthesized in vitro should be preserved, but for those produced by metabolism should be declined. Except India, most countries under investigation comport with this dichotomy. Their jurisprudence may be subsumed into …

The Effect Of Contextual Variables On Intraspecific Interactions And Space-Use In Meadow Voles, Microtus Pennsylvanicus, Christian Thomas Vlautin

Electronic Theses and Dissertations Archive

The outcomes of social interactions may depend on the circumstances of the encounter. Using a variety of social and environmental cues, I tested the hypothesis that the responses of meadow voles to conspecifics would be affected by the context in which that encounter occurred. Chapter two describes experiments showing that unlike long-photoperiod (LP) voles, which prefer the top-scent donor to the bottom-scent donor of an over-mark, only some short-photoperiod (SP) males showed such preferences, and no SP females preferred the top-scent donor to the bottom-scent donor of an over-mark. Chapter three details experiments demonstrating that periods of food deprivation did …