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Contents, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Discovery: The Student Journal Of Dale Bumpers College Of Agricultural, Food And Life Sciences - Volume 14 2013, Several Authors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Letter From The Dean, Michael Vayda

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Instructions For Authors, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

An In Silico Liver: Model Of Gluconeogenesis, Elie R. Chalhoub

ETD Archive

An in silico liver was developed in attempt to represent the in vivo state of the fasted liver. It featured two conceptual models. The first one represented carbohydrate metabolism of the human liver, which included the heterogeneous nature of the liver by incorporating spatial variation of key enzyme activities. This model was able to predict the overall fluxes in tissue and the effect of high intensity exercise on the various hepatic fluxes. A second model of hepatic metabolism was developed to represent the complex interplay between gluconeogenesis, lipid metabolism, and alcohol metabolism in the fasted rat liver. Biochemical pathways are …

Do Psychologists Demonstrate Bias Based On Female Client Weight And Ethnicity? ;An Analogue Study, Lindsay C. Varkula

ETD Archive

Although anti-fat bias and discrimination have been widely documented (see Puhl, Andreyeva, & Brownell, 2008), few studies have examined whether psychologists exhibit biases toward clients who are fat. Only one study (Locker, 2011) examined whether client characteristics of ethnicity and weight influenced therapists' bias no studies have exclusively examined psychologists. This analogue study investigated psychologists' biases toward a hypothetical client (vignette adapted from Zadroga, 2009) when the client characteristics of weight (average/obese) and ethnicity (African American/European American) were manipulated. Participants in this study included a national sample of 194 licensed, currently practicing psychologists. A 2 (client weight) x 2 (client …

Lipid Production By Scenedesmus Dimorphus: Comparison Of Extraction Techniques And Effect Of Sodium Nitrate Concentration, Bahareh Kanani

ETD Archive

No abstract provided.

Singing Behavior And Geographic Variation In The Songs Of The Veery (Catharus Fuscescens) Across The Appalachian Mountains, Courtney L. Brennan

ETD Archive

The Veery (Catharus fuscescens) is a common Neotropical migrant thrush whose breeding distribution spans the Northern United States and southern Canada and continues south through the high elevations of the Appalachian Mountains. Despite its wide distribution, many aspects of Veery biology are largely unknown, including a clear characterization of song and knowledge of geographic song variation. I describe the song structure, repertoire size, and patterns of song delivery in the songs of the Veery and describe geographic song variation across four regions along the Appalachian Mountains. Visual analysis of song spectrogram images of territorial males revealed that Veeries' repertoire ranges …

Emerging Imagery: The Great Famine In Nineteenth Century Irish Lit, Barbara A. Pitrone

ETD Archive

The critical debate surrounding the Great Famine in Irish Literature centers on the notion of a perceived silence. While some scholars claim that there is a literary void in Irish Literature following this cataclysmic event, others wonder whether language is even capable of describing the extreme physical, emotional, and psychological suffering that is inflicted upon the victims when such tragedies occur. Centuries of imperialism and colonialism had created a class divide so wide and an Irish economy so fragile that when a calamity such as famine occurred, it was the poverty-stricken, predominately Irish-Catholic peasantry that suffered most. Poor and illiterate, …

Assessment Of Verbal And Nonverbal Memory And Learning In Abstinent Alcoholics, Alyson L. Phelan

ETD Archive

Neuropsychological performance was measured in chronic alcoholics who maintained abstinence for at least six months and with matched controls. Specifically, measures of verbal memory were assessed utilizing the Rey Auditory Verbal Learning Test (RAVLT) and measures of nonverbal memory with the Rey Osterreith Complex Figure Test (ROCF) and a new measure, the Poreh Nonverbal Memory Test (PNMT). In addition, both the RAVLT and the PNMT provide a measure of operationalized learning, as they are multi-trial tasks utilizing five trials to assess recall in each trial. Verbal memory includes the ability to encode, store and retrieve information for words, language and …

Assessment Of Freshwater Mussel Communities Of Small Stream Mouths Along Lake Erie, Trevor J. Prescott

ETD Archive

Invasion of lakes and rivers by dreissenid mussels pushed out native species, particularly freshwater mussels in the Unionidae, across the northern hemisphere, and perhaps most infamously, within the Laurentian Great Lakes. However, several coastal areas along the shallowest of these lakes, Lake Erie, may be refugia for native species, but the conditions under which native species persist are unknown. I surveyed river mouths of small streams along the Lake Erie coastline and compared species abundance to land use assessed by remote sensing techniques and to standard measures of water chemistry. Sampling focused on stream zones influenced by lake-water levels for …

Computational Fluid Dynamics Modeling Of A Gravity Settler For Algae Dewatering, Scott A. Hug

ETD Archive

Algae are the future of lipid sources for biodiesel production. Algae can produce more biodiesel than soybean and canola oil and can be grown in more diverse locations. Algae concentrations are naturally around 0.1 by weight. Enough water must be removed for the algae level to reach 5 , the minimum concentration in which lipids can be used in the transesterification process for biofuel production is 5 . Current dewatering methods involve the use of settling tanks and centrifugation. The costs of centrifugation limit the commercial viability of algae based biodiesel. A novel inclined gravity settler design at Cleveland State …

Identification Of New Genes Involved In Meiosis By A Genetic Screen, Sneharthi Banerjee

ETD Archive

Budding yeast Saccharomyces cerevisiae contains a group of proteins named ZMM that constitutes a link between recombination and Synaptonemal Complex (SC) assembly. Yeast mutants that lack ZMM proteins have defects in recombination, SC formation and nuclear division progression. Meiotic cell cycle progression in zmm mutants is modulated by temperature. This conditional behavior is different at high and low temperatures. In my work so far, I have tried to identify new zmm-like genes involved in meiosis. To that end, I have carried out a genome-wide screen in the budding yeast S. cerevisiae. I have identified sporulation temperature sensitive zmm-like truncation mutants …

Dakota, Norman K. Risjord

University of Nebraska Press: Sample Books and Chapters

The northern plains are often ignored by the rest of the nation or, if not, are mentioned in the context of the weather, Mount Rushmore, or the Black Hills. However, North Dakota and South Dakota have a colorful past—and present—deserving of greater recognition. Norman K. Risjord relates the remarkable histories of these two states, from the geological formation of the Great Plains to economic changes in the twenty-first century. Risjord takes the reader on a journey through the centuries detailing the first human inhabitants of the northern plains, the Lewis and Clark expedition, homesteading and railroad building, the political influence …

Unopa 50th Anniversary Booklet

UNOPA: Special Events

No abstract provided.

Hospitality Management: A Guide To Key Reference Works, Tim Bottorff

Faculty Scholarship and Creative Works

Purpose
– This paper aims to provide an overview of the field of hospitality management and a guide to the major books, databases, web sites, and other resources that comprise a quality hospitality management reference collection.

Design/methodology/approach
– Following a short introduction and overview, key sources and annotations are presented in categories that will help reference and collection librarians to better understand and serve hospitality management students. The sources were identified through the author's experience, library research guides and web sites, bibliographies, and other standard sources.

Findings
– Hospitality management is growing and maturing as an academic discipline, aided by …

Divided Diasporas: Southern Africans In Canada, Jonathan Crush, Abel Chikanda, Wade Pendleton, Mary Caesar, Sujata Ramachandran, Cassandra Eberhardt, Ashley Hill

Southern African Migration Programme

The protracted economic and political crisis in Zimbabwe led directly to a major increase in mixed migration flows to South Africa. Migrants were drawn from every sector of society, all education and skill levels, equal numbers of both sexes, and all ages (including unaccompanied child migration). Many migrants claimed asylum in South Africa which gave them the right to work while they waited for a refugee hearing. Many others were arrested and deported back to Zimbabwe. Migrants who were unable to find employment in the formal economy turned to employment and self-employment in the informal economy. These migrant entrepreneurs used …

No. 17: The State Of Food Insecurity In Gaborone, Botswana, Ben Acquah, Stephen Kapunda, Alexander Legwegoh, Thando Gwebu, Tirelo Modie-Moroka, Kesitegile Gobotswang, Aloysius Mosha

African Food Security Urban Network

The results of AFSUN’s study of the food security situation of the poor in Gaborone show that not everyone is benefitting from Botswana’s strong and growing economy and that many of the urban poor experience extremely high levels of food insecurity. The study, which formed part of AFSUN’s baseline survey of 11 Southern African cities, collected data on a broad range of issues that affect household food insecurity and found that four out of five households in the surveyed areas in Gaborone reported severe or moderate food insecurity. Only 18% were either food secure or mildly food insecure. Income level …

Multiple Environmental Chemical Exposures To Lead, Mercury And Polychlorinated Biphenyls Among Childbearing-Aged Women (Nhanes 1999–2004): Body Burden And Risk Factors, Marcella Remer Thompson, Kim Boekelheide

College of Nursing Faculty Publications

Background: Lead, mercury and polychlorinated biphenyls (PCBs) are neurotoxicants with intergenerational health consequences from maternal body burden and gestational exposures. Little is known about multiple chemical exposures among childbearing-aged women.

Objectives: To determine the percentage of women aged 16–49 of diverse races and ethnicities whose body burdens for all three xenobiotics were at or above the median; to identify mixed exposures; and to describe those women disproportionately burdened by two or more of these chemicals based on susceptibility- and exposure-related attributes, socioeconomic factors and race-ethnicity.

Methods: Secondary data analysis of National Health and Nutrition Examination Survey (1999–2004).

Results: The best-fit …

Factors Influencing The Implementation Of Organized Physical Activity And Fruit And Vegetable Snacks In The Hop'n After-School Obesity Prevention Program, Tanis J. Hastmann, Melissa Bopp, Elizabeth A. Fallon, Richard R. Rosenkranz, David A. Dzewaltowski

Public Health Faculty Publications

Objective: To identify barriers and facilitators for improving the after-school organized physical activity (PA) and snack quality.

Methods: After-school staff (Year 1, n = 20; Year 2, n = 17) participated in qualitative, semistructured interviews about the implementation of an after-school obesity prevention intervention. Interviews were recorded, transcribed, coded for common themes, and analyzed using NVivo software.

Results: Several factors influencing implementation of PA and fruit and vegetable (FV) consumption were revealed. Facilitators for PA included: staff training, equipment/gym space, and scheduling organized PA. Physical activity barriers included prioritizing PA and lack of school administration support. Fruit and vegetable facilitators …

Assessment Of The Dining Environment On And Near The Campuses Of Fifteen Post-Secondary Institutions, Tanya M. Horacek, Maria B. Erdman, Carol Byrd-Bredbenner, Gale Carey, Sarah M. Colby, Geoffrey W. Greene, Wen Guo, Kendra K. Kattlemann, Melissa Olfert, Jennifer Walsh, Adrienne B. White

Nutrition Faculty Publications

Objective:

The present study evaluated the restaurant and dining venues on and near post-secondary campuses varying in institution size.

Design:

The Nutrition Environment Measures Survey for Restaurants (NEMS-R) was modified to evaluate restaurants as fast food, sit down and fast casual; and campus dining venues as dining halls, student unions and snack bar/cafés. ANOVA with post hoc Tukey's B and T tests were used to distinguish differences between dining venues and associated institutions by size.

Setting:

The study was conducted at fifteen US post-secondary institutions, 2009–2011.

Subjects:

Data presented are from a sample of 175 restaurants …

The Lived Experience Of Weight Retention Among Postpartum African American Adolescents, Thelma Mae Phillips

Wayne State University Dissertations

Background: Obesity presents a public health challenge and is a serious chronic medical condition, which is associated with multiple co-morbidities and reduced survivability/longevity (Davis, Stange, & Howitz, 2010). African American adolescents who retain weight after pregnancy are at the highest risk of becoming obese adults. Obesity is expected to cost the United States health care system over 237 million dollars (National Institutes of health, 2011) within the next decade.

The prevalence of obesity is cause for concern because of its costs to the economic base of the country and its toll in human suffering due to related morbidity and mortality. …

Socioeconomic Differences In Body Mass Index, Neighborhood Satisfaction, Stress, And Perceived Racism Among African Americans In Metropolitan Detroit, Corey Zolondek

Wayne State University Dissertations

This exploratory study tested the research hypothesis that among African Americans in Metropolitan Detroit, neighborhood satisfaction, stress and perception of racism influence obesity differently based on income. The three expected results for the data were as follows: income does not have a link to obesity; links between BMI and the study variables (neighborhood satisfaction, stress, and perceived racism) vary according to income category; and the study variables (neighborhood satisfaction, stress, and perceived racism) influence the variability of BMI differently according to income category. The results indicate that there are no income differences in how the study variables influence obesity. Therefore, …

The Role Of Cardiolipin In Iron Homeostasis And Glutathione Metabolism, Vinay A. Patil

Wayne State University Dissertations

Cardiolipin (CL) is the signature phospholipid of mitochondrial membranes, where it is synthesized locally and plays a critical role in mitochondrial bioenergetic functions. Inside the mitochondria, CL is a critical target of mitochondrial generated reactive oxygen species (ROS) and regulates signaling events related to apoptosis and aging. CL deficiency causes perturbation of signaling pathways outside the mitochondria, including the PKC-Slt2 cell integrity pathway and the high osmolarity glycerol (HOG) pathway, and is a key player in the cross-talk between the mitochondria and the vacuole. The importance of CL in human health is underscored by the observation that perturbation of CL …

Characterization Of Antimicrobial-Resistant Staphylococcus Spp. In Food Animals And Retail Meat, Kanika Bhargava

Wayne State University Dissertations

Antimicrobial resistance in Staphylococcus spp. is a worldwide epidemic concern in hospital and community settings. Food animals and retail meat are important reservoirs of these pathogens that can pose potential threat to humans. In this dissertation, we aimed to investigate the molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Coagulase-negative Staphylococci (MRCoNS) in food animals and retail meat to provide insight into the role of agricultural environment in transmitting bacteria of human clinical significance. Furthermore, the potential application of phytochemicals as antimicrobials and antimicrobial adjuvants to control MRSA infections was explored.

CoNS recovered from food animals were characterized by …

Striatal Dopamine Dynamics Upon Manganese Accumulation, Madiha Khalid

Wayne State University Dissertations

STRIATAL DOPAMINE DYNAMICS UPON MANGANESE ACCUMULATION

by MADIHA KHALID

August 2013

Advisor: Dr. Tiffany Mathews

Major: Chemistry (Analytical)

Degree: Doctor of Philosophy

Although manganese (Mn) is fundamental for many biological processes, exposure to excess amounts leads to a neurological disorder termed manganism. Due to its symptomatic similarity to Parkinson's disease, as well its preferential accumulation in dopamine rich brain regions, alterations in the dopamine system are implicated in the onset of manganism. In my research, Mn overexposure is mimicked via subcutaneous administration of manganese chloride to C57BL/6 mice over the course of seven days using a protocol that has been …

Linking Environmental Toxicant Exposure To Diabetes Susceptibility, Jannifer Beth Tyrrell

Wayne State University Dissertations

An important and unresolved question in the environmental health field is whether exposure to common environmental toxicants, such as dioxin and heavy metals like Pb, increase the risk of developing diabetes, especially in combination with other common metabolic stressors such as obesity.

Previous studies suggested that dioxin exposure increased peripheral insulin resistance but did not appear to cause fasting hyperglycemia or elevated hepatic glucose output. In concordance with those findings we observed that dioxin treatment caused a strong suppression of the expression of the key hepatic gluconeogenic genes PEPCK and G6Pase. However, this suppression was not solely mediated by the …

The Effect Of Proalgazyme And Its Subfractions On Lipid Metabolism In Diet Induced Hypercholesterolemic Hamsters: Correlation With Plasma Metabolomic Profile, Andreea Geamanu

Wayne State University Dissertations

ABSTRACT

THE EFFECT OF PROALGAZYME AND ITS SUBFRACTIONS ON LIPID METABOLISM IN DIET INDUCED HYPERCHOLESTEROLEMIC HAMSTRES:

CORREALTION WITH PLASMA METABOLOMIC PROFILE

by

ANDREEA GEAMANU

December 2013

Advisor: Dr. Smiti Gupta

Major: Nutrition and Food Science

Degree: Doctor of Philosophy

Background: Plasma HDL cholesterol levels are inversely related to cardiovascular disease, which is the leading cause of death worldwide. This study investigated the preventative effect of an algae infusion, ProAlgaZyme (PAZ) and its subfractions (F1, F2, F3, F4) on plasma HDL in a hamster model. Further, the study aimed to identify the biologically active fraction of PAZ and to determine the …

Desensitization Of Basal Cell Carcinoma To The Anti-Tumoral Effect Of Vitamin D, Rawia Khasawneh

Wayne State University Dissertations

The relationship between Vitamin D and NMSC is not very clear. Most of human studies in literature in regards to vitamin D and NMSC are epidemiological which are inconsistent and inconclusive. Mechanistic studies about BCC are few, and mostly are animal models or cell cultures. The main goal for this study is to interpret the impact of vitamin D status on the onset and progression and possibly treatment of basal cell carcinoma. Three tissue samples were collected from BCC patients (Cancer, Proximal, and Distal), and from cancer-free individuals from southeast Michigan. This study design helps identifying alterations in the genetic …

Sleep Homeodynamics And Wellbeing In Asymptomatic Hiv-Seropositive African American Women, Tabetha Lynn Gayton

Wayne State University Dissertations

SLEEP HOMEODYNAMICS AND WELLBEING IN ASYMPTOMATIC HIV–SEROPOSITIVE AFRICAN AMERICAN WOMEN

by

TABETHA LYNN GAYTON

December 2013

Advisor: Hossein N. Yarandi, PhD

Major: Nursing (Urban Health)

Degree: Doctor of Philosophy

BACKGROUND: HIV–related sleep disruption is a common complaint of persons with HIV infection. With the demographical shifts, African American women have now emerged as one of the fastest growing HIV populations today, yet they remain a vulnerable and underrepresented population in the sleep literature.

OBJECTIVE: The purpose of this pilot study was to explore the dynamics of HIV–related sleep disruption and wellbeing in asymptomatic HIV–seropositive AA women of childbearing age within …