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October 2013 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Approval And Withdrawal Of New Antibiotics And Other Antiinfectives In The U.S., 1980-2009, Kevin Outterson, John H. Powers, Enrique Seoane, Rosa Rodriguez-Monguio, Aaron S. Kesselheim

Faculty Scholarship

Concerns about a dearth of antibiotic innovation have spurred calls for incentives to speed the development of new antibiotics. Our data demonstrates that many of the new molecular entity (NME) antibioticsintroduced in the last 3 decades were withdrawn from the market, at more than triple the rate of other drug classes. Adjusted for these withdrawals, the net introduction of NME antibiotics is not as troubling of a trend. The reduction in NME antibiotics was partially offset by a surge in the introduction of NME antiretrovirals for HIV/AIDS and other drug classes (such as cardiovascular drugs) posted similar declines.

These data …

Using Role-Play To Enhance Foodborne Illness Crisis Management Capacity In The Produce Industry, Audrey Kreske, Diane Ducharme, Chris Gunter, Trevor Phister, Benjamin Chapman

Journal of Extension

Foodborne illness outbreaks have measurable public health effects and often lead to negative produce industry impacts. Reducing loss following a crisis event requires a management plan, although many fresh produce industry members don't have one. Evidence-based workshops using a role-play simulated outbreak were delivered to impact crisis management preparation. A self-reported pre-assessment demonstrated that 21% of participants had a crisis management plan in place prior to attendance, with 79% who employed GAPs. Following the role-play scenario, there was a significant increase in participants' perception of the likelihood of microbial contamination with their product and an increase in crisis planning activities.

A New Health Informatics Course: A Funded Collaboration, Xinyu Yu

SLIS Connecting

Information access is considered critical to the public health workforce, which involves informatics, communication, analytic assessment, and health education (NN/LM Public Health Training Workgroup, 2004). Information-oriented outreach to the public health workforce is challenging to libraries because the public health workforce is made up of diverse health professions and public health personnel are not aware if key information resources are available to them (Cogdill, 2007). The National Library of Medicine (NLM) funded information outreach to the public health workforce projects in different periods of time, which altogether reflect challenges of providing public health professionals with access to electronic health information …

September 30, 2013, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Effects Of Invasive Plants On Biodiversity Across Spatial Scales, Kristin Irene Powell

All Theses and Dissertations (ETDs)

Although introduced plant species are often considered to be one of the most notable anthropogenic threats to biodiversity, their influence on biodiversity remains controversial. Some studies have shown large declines in biodiversity in plant-invaded areas, whereas others have noted that plant invasions are rarely implicated as the cause of species extinctions. This dissertation aims to synthesize this seemingly conflicting literature on the effects of invasive plants on biodiversity. The overarching hypothesis in this research is that the effect of invasive plant species on biodiversity is scale-dependent, and the discrepancy among studies can be explained by a difference in the scales …

Multi-Criteria Decision Analysis As An Innovative Approach To Managing Zoonoses: Results From A Study On Lyme Disease In Canada, Cécile Aenishaenslin, Valérie Hongoh, Hassane D. Cissé, Anne Gatewood Hoen

Dartmouth Scholarship

ackground: Zoonoses are a growing international threat interacting at the human-animal-environment interface and call for transdisciplinary and multi-sectoral approaches in order to achieve effective disease management. The recent emergence of Lyme disease in Quebec, Canada is a good example of a complex health issue for which the public health sector must find protective interventions. Traditional preventive and control interventions can have important environmental, social and economic impacts and as a result, decision-making requires a systems approach capable of integrating these multiple aspects of interventions. This paper presents the results from a study of a multi-criteria decision analysis (MCDA) approach for …

Antiretroviral Therapy (Art) Side Effect Impacted On Quality Of Life, And Depressive Symptomatology: A Mixed-Method Study, Wei-Ti Chen, Cheng-Shi Shiu, Joyce Yang, Jane M. Simoni, Karen Fredriksen-Goldsen, Tony Szu-Hsien Lee, Hongxin Zhao

Psychology

Antiretroviral therapy (ART) is known for its side effects. In this paper, we describe ART side effects as experienced by Chinese HIV+ individuals. This study presents two stages of a research project, combining qualitative in-depth interviews (29 HIV+ participants) with quantitative statistical data analysis (N = 120). All data was collected between July 2005 to March 2008 at Beijing's Ditan Hospital. Consent was obtained from each participant for the qualitative interview and again for the quantitative survey. During in-depth interviews, Chinese HIV+ patients reported experiencing digestive discomfort, skin rashes, numbness, memory loss, nightmares, and dizziness, which not only brought them …

Support And Barriers To Help Seeking In Latina/O Migrant Workers, Rachel Becker

Open Access Dissertations

This dissertation explored help seeking for mental health concerns in migrant workers using a community-based mixed-methods design. Specifically, the study asked two sets of questions; the first explored individual-level predictors of help seeking and the second focused on contextual-level factors related to mental health, well-being, and help seeking. Participants were 95 Latina/o migrant workers living in South Florida. A portion of these individuals participated in the qualitative phase. Hierarchical regression analyses were used to answer the first set of questions. Results indicated informal help seeking was predicted by gender, acculturation, coping strategy, depressive symptomology, and attitudes toward seeking professional help. …

Infection Blocks Trash Removal To Cause Ulcers, Cancer, Greg Williams

Browse All News

No abstract provided.

A Novel Subnetwork Alignment Approach Predicts New Components Of The Cell Cycle Regulatory Apparatus In Plasmodium Falciparum, Hong Cai, Changjin Hong, Timothy G. Lilburn, Armando L. Rodriguez, Sheng Chen, Jianying Gu, Rui Kuang, Yufeng Wang

Publications and Research

Background According to the World Health organization, half the world's population is at risk of contracting malaria. They estimated that in 2010 there were 219 million cases of malaria, resulting in 660,000 deaths and an enormous economic burden on the countries where malaria is endemic. The adoption of various high-throughput genomics-based techniques by malaria researchers has meant that new avenues to the study of this disease are being explored and new targets for controlling the disease are being developed. Here, we apply a novel neighborhood subnetwork alignment approach to identify the interacting elements that help regulate the cell cycle of …

September 23, 2013 Aasu Faculty Senate Agenda, Armstrong State University

Armstrong Faculty Senate: Armstrong Faculty Senate Agenda (Archived)

September 23, 2013 AASU Faculty Senate Agenda

Faculty Senate Bill Fsb-2013-09-23-02: Graduate Affairs Committee, Armstrong Atlantic State University

Armstrong Faculty Senate: Bills, Motions & Resolutions (Archived)

Faculty Senate Bill FSB-2013-09-23-02: Graduate Affairs Committee

2013 Student Center For Science Engagement Fifth Annual Research Symposium, Student Center For Science Engagement

Student Center for Science Engagement Research Symposium

Featuring student presentations in: Biology, Chemistry, Computer Science, Earth Science, Mathematics, Physics, and Psychology

Reported Incidences Of Parasitic Infections In Marine Mammals From 1892 To 1978, John R. Felix

Zea E-Books Collection

The role of parasites in the lives and deaths of marine mammals has been scrutinized by biologists for decades, but the scientific literature prior to 1978 has been difficult to acquire and time-consuming to search. Now this new and extensive bibliography gives researchers a convenient resource for reviewing the classical literature on parasites of marine mammals so that historical infection prevalence and geographical distribution can be easily and properly assessed. This book contains detailed information about accepted (or suspected) taxonomic synonyms and geographical information about the host and/or parasite, covering the parasite groups Acanthocephala, Acarina, Anoplura, Cestoda, Nematoda, and Trematoda, …

Senior Biology Major Earns Undergraduate Microbiology Award, Winthrop University

Winthrop News 2013

• The biology major has worked in faculty member Matt Heard’s lab for a year where she is studying whether there is a link between the introduction of exotic mammals and the emergence of infectious diseases in humans.
• Hardwick also is an undergraduate teaching assistant working with Vicki Frost in her microbiology classes in a job that is normally reserved for a graduate student.

Immunization With Cross-Conserved H1n1 Influenza Cd4+ T-Cell Epitopes Lowers Viral Burden In Hla Dr3 Transgenic Mice, Leonard Moise, Ryan Tassone, Howard Latimer, Frances Terry, Lauren Levitz, John P. Haran, Ted M. Ross, Christine Boyle, William D. Martin, Anne S. De Groot

Cell and Molecular Biology Faculty Publications

The emergence of the pandemic H1N1 strain of influenza in 2009 was associated with a unique w-shaped age-related susceptibility curve, with higher incidence of morbidity and mortality among young persons and lower incidence among older persons, also observed during the 1918 influenza pandemic. Pre-existing H1N1 antibodies were not cross-reactive with the prior seasonal vaccine, forcing influenza experts to scramble to develop a new vaccine specific for the pandemic virus. We hypothesized that response to T-cell epitopes that are cross-conserved between pandemic H1N1 and the 2008 seasonal influenza vaccine strains might have contributed to partial protection from clinical illness among older …

Method For Enhancing Specific Immunotherapies In Cancer Treatment, Peter G. Traber, William L. Redmond, Eliezer Zomer, Anatole Klyosov, Stefanie N. Linch

Technology Transfer - Patents

Methods and compositions of the invention relate to the enhancement of specific immunotherapies in cancer treatment. In particular, aspects of the invention relate to novel approaches to boost immune function using a complex carbohydrate pharmaceutical compound alone or in combination with other targeted immunotherapy to increase the efficacy of immunotherapy of cancer.

Critical Connectivity In Banking Networks, Agam Gupta, Molly M. King, James Magdanz, Regina Martinez, Matteo Smerlak, Brady Stoll

Sociology

The financial crisis of 2007-2009 demonstrated the need to understand the macrodynamics of interconnected financial systems. A fruitful approach to this problem regards financial infrastructures as weighted directed networks, with banks as nodes and loans as links. Using a simple banking model in which banks are linked through interbank lending, with an exogenous shock applied to a single bank, we find a closedform analytical solution for the degree at which failures begin to propagate in the network. This critical degree is expressed as a function of four financial parameters: banking leverage; interbank exposure; return on the investment opportunity; and interbank …

A Study On The Geophylogeny Of Clinical And Environmental Vibrio Cholerae In Kenya, J. Kiiru, A. Mutreja, A. A. Mohamed, R. W. Kimani, J. Mwituria, R. O. Sanaya, J. Muyodi, Gunturu Revathi, J. Parkhill, N. Thomson, G. Dougan, S. Kariuki

Pathology, East Africa

Cholera remains a significant public health challenge in many sub-Saharan countries including Kenya. We have performed a combination of phylogenetic and phenotypic analysis based on whole genome DNA sequences derived from 40 environmental and 57 clinical V. cholerae from different regions of Kenya isolated between 2005 and 2010. Some environmental and all clinical isolates mapped back onto wave three of the monophyletic seventh pandemic V. cholerae El Tor phylogeny but other environmental isolates were phylogenetically very distinct. Thus, the genomes of the Kenyan V. cholerae O1 El Tor isolates are clonally related to other El Tor V. cholerae isolated elsewhere …

Comparison Of Hpv Dna Testing In Cervical Exfoliated Cells And Tissue Biopsies Among Hiv-Positive Women In Kenya, Hugo De Vuyst, Michael Chung, Lacopo Baussano, Nelly R. Mugo, Vanessa Tenet, Folkert J. Van Kemenade, Farzana S. Rana, Samah R. Sakr, Chris J.L.M. Meijer, Peter J.F. Snijders, Silvia Franceschi

Pathology, East Africa

HIV-positive women are infected with human papillomavirus (HPV) (especially with multiple types), and develop cervical intraepithelial neoplasia (CIN) and cervical cancer more frequently than HIV-negative women. We compared HPV DNA prevalence obtained using a GP5+/6+ PCR assay in cervical exfoliated cells to that in biopsies among 468 HIV-positive women from Nairobi, Kenya. HPV prevalence was higher in cells than biopsies and the difference was greatest in 94 women with a combination normal cytology/normal biopsy (prevalence ratio, PR = 3.7; 95% confidence interval, CI: 2.4-5.7). PR diminished with the increase in lesion severity (PR in 58 women with high-grade squamous intraepithelial …

Averting Hiv Infections In New York City: A Modeling Approach Estimating The Future Impact Of Additional Behavioral And Biomedical Hiv Prevention Strategies, Jason Kessler, Julie E. Myers, Kimberly A. Nucifora, Nana Mensah, Alexis Kowalski, Monica Sweeney, Christopher Toohey, Amin Khademi, Colin Shepard, Blayne Cutler, R. Scott Braithwaite

Publications

Background: New York City (NYC) remains an epicenter of the HIV epidemic in the United States. Given the variety of evidence-based HIV prevention strategies available and the significant resources required to implement each of them, comparative studies are needed to identify how to maximize the number of HIV cases prevented most economically.

Methods: A new model of HIV disease transmission was developed integrating information from a previously validated micro-simulation HIV disease progression model. Specification and parameterization of the model and its inputs, including the intervention portfolio, intervention effects and costs were conducted through a collaborative process between the academic modeling …

Antibiotic Thin Films, Timothy Jennings, Jason Nielsen, Brian Ratcliff, Nina Wallace, Xin Zhong Lai, Paul B. Savage

Journal of Undergraduate Research

Nosocomial infections lead to septicemia, a severe problem in the United States. The Savage group has developed a novel class of antibiotics (CSAs) that can be attached to polymers. Invasive medical equipment can be coated with CSA polymers, forming an antibiotic thin film. Testing has shown the ability of CSA polymers to kill bacteria, which will lead to further testing and future use in the medical field.

Accreditation And Standardization In Local Public Health, Glen P. Mays

Health Management and Policy Presentations

Reducing harmful, wasteful, and inequitable variation in public health delivery is a central objective for administrative and policy decision-makers in public health, and is embedded in the national accreditation movement. The challenge lies in accomplishing this objective while preserving the benefits of customization in public health delivery that accrue through tailoring and targeting of resources to unique community needs and risks. Public health services and systems research (PHSSR) can help determine the optimal balance between standardization and customization in public health delivery.

Multidrug-Resistant Tuberculosis: Strategies For Identification And Control, Wendy Chao, Dr. Richard Robison

Journal of Undergraduate Research

After over a century of decline, tuberculosis (TB) has re-emerged as the leading killer among infectious diseases. In addition, Mycobacterium tuberculosis, the causative agent of TB, has developed strains resistant to multiple antibiotics, making the disease increasingly difficult to treat.

More Than Just An Exchange : How Does Access To Syringe Exchange Impact Actively Using Participants' Emotional Well-Being, Melissa A. Morelli

Theses, Dissertations, and Projects

This qualitative, exploratory study examines how accessing Syringe Access Services (SAS) directly impacts program participants' emotional well-being. The purpose of this research is to give voice to individuals who utilize SAS services; to gain personal and valuable information about the nature of the participant; and to reveal the emotional and mental health outcomes linked with SEP's. Twelve individuals who have been program participants of SAS for over a year were interviewed for this study. Participants were interviewed indoors at one of the SAS's fixed needle exchange sites in the Bay Area. In-person semi-structured interview questions elicited participants' experience with various …

Ki Moun Mwen Ye? : Who Am I? : Factors Associated With Cultural Identity Formation In First Generation Haitian Americans, Joan V. Monplaisir

Theses, Dissertations, and Projects

This qualitative study explores the factors associated with cultural identity formation among first generation Haitian Americans (FGHA) born in the United States between 1975 and 1990. The purpose of this study is to inform clinical social work practice with immigrants and their families in a range of areas including the experience of cultural identity development and the process and effects of acculturation in the U.S. Audiotaped in-person and telephone semi-structured interviews elicited participant perceptions of, and connection to, a range of aspects of Haitian culture. Participants' experience of dominant U.S. cultural views of Haiti and the Haitian people, understanding of …

Weekly News Digest 09/11/2013, Jenna Ray

Weekly Bulletin Archive

In this issue:

● Thursday Afternoon Faculty Seminars Resume

● Morris to Host Gloria Ladson-Billings This Fall

● Morris Named a Top 10 Public Liberal Arts College

● Livingston Receives Pay it Forward Stevens County Award

Volume 51, Number 4: September 11, 2013, University Of North Dakota

University Letter Archive

No abstract provided.

Strengthening The Evidence Base For Accreditation: Progress In Phssr And Pbrns, Glen P. Mays

Health Management and Policy Presentations

With the launch of a voluntary national accreditation program for public health agencies, the field requires an expanding evidence base concerning which public health strategies work best, for which populations, and under what circumstances. The field of public health services and systems research (PHSSR) and practice-based research networks (PBRNs) are producing applied studies that can inform the future development and implementation of accreditation standards, and evaluate the impact of accreditation on the field of practice.