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2013

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Surgical Patient Education Material And The Infection Related-Content, Dinah K. Arifulla, Helena Leino-Kilpi, Helj' Lundgren-Laine Oct 2013

Surgical Patient Education Material And The Infection Related-Content, Dinah K. Arifulla, Helena Leino-Kilpi, Helj' Lundgren-Laine

International Nursing Research Congress (INRC)

Session presented on: Friday, July 26, 2013:

Purpose: Infection control priorities have been to reduce surgical site infections and to increase patients' participatory by empowering patient education. In patient education, it is common to use written material, which should to be understandable and support patients' empowerment. Surgical patient education (PE) materials should have a good quality of the content, support patients empowerment and participation in care as well as reduce surgical site infections and improve patient safety. However, the systematic information on the infection control content and the quality of materials is missing. The purpose was to analyze the surgical …


The New Hampshire, Vol. 103 [104], No. 12 (Oct. 22, 2013), The New Hampshire Oct 2013

The New Hampshire, Vol. 103 [104], No. 12 (Oct. 22, 2013), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 103, but it is the 104th volume in the series. This was corrected in pencil.


Testing The Effectiveness Of A New Device To Prevent Medical Line Entanglement In Pediatric Patients, Heather Janiszewski Goodin, Nancy A. Ryan-Wenger, Pamela Creech, Joyce Mullet Oct 2013

Testing The Effectiveness Of A New Device To Prevent Medical Line Entanglement In Pediatric Patients, Heather Janiszewski Goodin, Nancy A. Ryan-Wenger, Pamela Creech, Joyce Mullet

International Nursing Research Congress (INRC)

Session presented on: Tuesday, July 23, 2013:

Purpose: Globally, unintentional injuries are the leading cause of death in children. In hospitalized children, unintentional injuries from medical line (ML) entanglements occur when lines become tangled, compressed, or looped around patients' necks or other body parts. The purpose of the study was to test the safety and effectiveness of a new medical device invented by a nurse called the ML Wrap, designed to prevent line entanglements in pediatric patients. The ML Wrap can be placed on intravenous lines, feeding tubes, oxygen tubes, and monitor cords to prevent patient harm such as strangulation, …


Tuberculosis In Nunavut: One Community's Initiative To Promote Awareness Through An Organized Community Health Fair, Dora Maria Carbonu Oct 2013

Tuberculosis In Nunavut: One Community's Initiative To Promote Awareness Through An Organized Community Health Fair, Dora Maria Carbonu

International Nursing Research Congress (INRC)

Session presented on: Thursday, July 25, 2013:

Purpose: Tuberculosis (TB) is a major public health problem, with a profound impact on the health of the population of Nunavut, where the highest number of 101 new active cases, were documented in 2010, a population rate 62 times the Canadian average, and involved adolescents and young adults. About 50% of the recorded cases were located in the capital city, placing a high demand on all sectors to enhance public health measures.

Methods: Evidence from one community's efforts to promote TB awareness, with related health behaviors, attitudes, and life styles, suggested that stigmatization …


Commonwealth Times 2013-10-21 Oct 2013

Commonwealth Times 2013-10-21

Commonwealth Times, 1969-

No abstract provided.


The Daily Egyptian, October 21, 2013, Daily Egyptian Staff Oct 2013

The Daily Egyptian, October 21, 2013, Daily Egyptian Staff

October 2013

No abstract provided.


Evidence Of Hantavirus Exposure In Rodents From North Texas, Richard M. Pitts, Matthew R. Mauldin, Cody W. Thompson, Jerry R. Choate Oct 2013

Evidence Of Hantavirus Exposure In Rodents From North Texas, Richard M. Pitts, Matthew R. Mauldin, Cody W. Thompson, Jerry R. Choate

Western North American Naturalist

Between 27 June 1997 and 16 May 1999, 423 rodents were collected from North Texas (Collin, Denton, and Grayson counties) by using Sherman live-traps (trapping success rate ~22%). Of the 423 rodents collected, 328 were tested for evidence of IgG antibodies to New World hantaviruses. Hantavirus antibodies were detected in 34 individuals (~10%). This is the first record of hantavirus antibody–positive rodents from the highly urbanized area of North Texas.


Entre el 27 de Junio 1997 y el 16 de Mayo 1999, 423 roedores fueron colectados usando trampas Sherman de capturas en vivo (éxito de captura ~22%) en el Norte …


Expression Of Mucoid Induction Factor Muce Is Dependent Upon The Alternate Sigma Factor Algu In Pseudomonas Aeruginosa, Yeshi Yin, F. Heath Damron, T. Ryan Withers, Christopher L. Prichett, Xin Wang, Michael J. Schurr, Hongwei Yu Oct 2013

Expression Of Mucoid Induction Factor Muce Is Dependent Upon The Alternate Sigma Factor Algu In Pseudomonas Aeruginosa, Yeshi Yin, F. Heath Damron, T. Ryan Withers, Christopher L. Prichett, Xin Wang, Michael J. Schurr, Hongwei Yu

Biochemistry and Microbiology

Background

Alginate overproduction in P. aeruginosa, also referred to as mucoidy, is a poor prognostic marker for patients with cystic fibrosis (CF). We previously reported the construction of a unique mucoid strain which overexpresses a small envelope protein MucE leading to activation of the protease AlgW. AlgW then degrades the anti-sigma factor MucA thus releasing the alternative sigma factor AlgU/T (σ22) to initiate transcription of the alginate biosynthetic operon.

Results

In the current study, we mapped the mucE transcriptional start site, and determined that PmucE activity was dependent on AlgU. Additionally, the presence of triclosan and …


October 18, 2013 Ereporter, University Of Alabama At Birmingham Oct 2013

October 18, 2013 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Population Genetics Of The Eastern Hellbender (Cryptobranchus Alleganiensis Alleganiensis) Across Multiple Spatial Scales., Shem D. Unger, Olin E. Rhodes Jr., Trent M. Sutton, Rod N. Williams Oct 2013

Population Genetics Of The Eastern Hellbender (Cryptobranchus Alleganiensis Alleganiensis) Across Multiple Spatial Scales., Shem D. Unger, Olin E. Rhodes Jr., Trent M. Sutton, Rod N. Williams

Department of Forestry & Natural Resources Faculty Publications

Conservation genetics is a powerful tool to assess the population structure of species and provides a framework for informing management of freshwater ecosystems. As lotic habitats become fragmented, the need to assess gene flow for species of conservation management becomes a priority. The eastern hellbender (Cryptobranchus alleganiensis alleganiensis) is a large, fully aquatic paedamorphic salamander. Many populations are experiencing declines throughout their geographic range, yet the genetic ramifications of these declines are currently unknown. To this end, we examined levels of genetic variation and genetic structure at both range-wide and drainage (hierarchical) scales. We collected 1,203 individuals from …


Membrane Vesicles Nucleate Mineralo-Organic Nanoparticles And Induce Carbonate Apatite Precipitation In Human Body Fluids, Cheng-Yeu Wu, Jan Martel, Wei-Yun Cheng, Chao-Chih He, David M. Ojcius, John Ding-E. Young Oct 2013

Membrane Vesicles Nucleate Mineralo-Organic Nanoparticles And Induce Carbonate Apatite Precipitation In Human Body Fluids, Cheng-Yeu Wu, Jan Martel, Wei-Yun Cheng, Chao-Chih He, David M. Ojcius, John Ding-E. Young

All Dugoni School of Dentistry Faculty Articles

Recent studies indicate that membrane vesicles (MVs) secreted by various cells are associated with human diseases, including arthritis, atherosclerosis, cancer, and chronic kidney disease. The possibility that MVs may induce the formation of mineralo-organic nanoparticles (NPs) and ectopic calcification has not been investigated so far. Here, we isolated MVs ranging in size between 20 and 400 nm from human serum and FBS using ultracentrifugation and sucrose gradient centrifugation. The MV preparations consisted of phospholipid-bound vesicles containing the serum proteins albumin, fetuin-A, and apolipoprotein A1; the mineralization-associated enzyme alkaline phosphatase; and the exosome proteins TNFR1 and CD63. Notably, we observed that …


Draft Genome Sequences Of Burkholderia Cenocepacia Et12 Lineage Strains K56-2 And Bc7, John J. Varga, Liliana Losada, Adrian M. Zelazny, Maria Kim, Jamison Mccorrison, Lauren Brinkac, Elizabeth P. Sampaio, David E. Greenberg, Indresh Singh, Cheryl Heiner, Meredith Ashby, William C. Nierman, Steven M. Holland, Joanna B. Goldberg Oct 2013

Draft Genome Sequences Of Burkholderia Cenocepacia Et12 Lineage Strains K56-2 And Bc7, John J. Varga, Liliana Losada, Adrian M. Zelazny, Maria Kim, Jamison Mccorrison, Lauren Brinkac, Elizabeth P. Sampaio, David E. Greenberg, Indresh Singh, Cheryl Heiner, Meredith Ashby, William C. Nierman, Steven M. Holland, Joanna B. Goldberg

Biochemistry and Molecular Medicine Faculty Publications

The Burkholderia cepacia complex (BCC) is a group of closely related bacteria that are responsible for respiratory infections in immunocompromised humans, most notably those with cystic fibrosis (CF). We report the genome sequences forBurkholderia cenocepacia ET12 lineage CF isolates K56-2 and BC7.


Reassessing Google Flu Trends Data For Detection Of Seasonal And Pandemic Influenza: A Comparative Epidemiological Study At Three Geographic Scales, Donald R. Olson, Kevin J. Konty, Marc Paladini, Cecile G. Viboud, Lone Simonsen Oct 2013

Reassessing Google Flu Trends Data For Detection Of Seasonal And Pandemic Influenza: A Comparative Epidemiological Study At Three Geographic Scales, Donald R. Olson, Kevin J. Konty, Marc Paladini, Cecile G. Viboud, Lone Simonsen

Global Health Faculty Publications

The goal of influenza-like illness (ILI) surveillance is to determine the timing, location and magnitude of outbreaks by monitoring the frequency and progression of clinical case incidence. Advances in computational and information technology have allowed for automated collection of higher volumes of electronic data and more timely analyses than previously possible. Novel surveillance systems, including those based on internet search query data like Google Flu Trends (GFT), are being used as surrogates for clinically-based reporting of influenza-like-illness (ILI). We investigated the reliability of GFT during the last decade (2003 to 2013), and compared weekly public health surveillance with search query …


Patent Protection For Pharmaceuticals: Ensuring Access To Enabling Innovation, Kim Speer Oct 2013

Patent Protection For Pharmaceuticals: Ensuring Access To Enabling Innovation, Kim Speer

Health Law and Policy Brief

No abstract provided.


Helminth Parasites Of The Raccoon (Procyon Lotor), Virginia Opossum (Didelphis Virginiana), And Striped Skunk (Mephitis Mephitis) From Keith County, Nebraska, Dennis J. Richardson Oct 2013

Helminth Parasites Of The Raccoon (Procyon Lotor), Virginia Opossum (Didelphis Virginiana), And Striped Skunk (Mephitis Mephitis) From Keith County, Nebraska, Dennis J. Richardson

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

Nine raccoons (Procyon lotor), 6 Virginia opossums (Didelphis virginiana), and 1 striped skunk (Mephitis mephitis) collected from Keith County, Nebraska were examined for helminth parasites. Raccoons were infected with the nematodes Arthrocephalus lotoris, Baylisascaris procyonis, and Capillaria plica, the trematode Fibricola cratera, and the tapeworm Atriotaenia procyonis. Opossums were infected with 1 nematode, 1 trematode, and 1 cestode species: Physaloptera turgida, Plagiorhchis elegans, and Oochoristica sp., respectively. The single striped skunk was infected with the nematode Physaloptera maxillaris and the cestodes Mesocestoides sp. and Oochoristica sp.


Animal Health Matters, Russ Daly Oct 2013

Animal Health Matters, Russ Daly

Animal Health MATTERS Newsletter

[Page] 1- Hennings named Veterinary and Biomedical Sciences Department Head [Page] 2- Director's Message: How Can We Serve You Better? [Page] 2- SDSU Pre-Veterinary Students Accepted to Veterinary Schools for Fall 2013 [Page] 3- SDVMA and SDSU Honor Pre-Veterinary Students with Stethoscopes [Page] 3- 2013-2014 SDSU Veterinary and Biomedical Sciences Department Scholarship Award Winners [Page] 4- Molecular Diagnostics Section Remains on the Cutting Edge [Page] 5- SDSU’s ADRDL Demonstrates Rapid Response to Need for Porcine Epidemic Diarrhea Virus (PEDV) Diagnostic Tests [Page] 6- Comings and Goings [Page] 6- New Faces Medicine [Page] 7- ADRDL Participates in SDVMA Annual Meeting [Page] …


Motivation To Reduce Risk Behaviors While In Prison: Qualitative Analysis Of Interviews With Current And Formerly Incarcerated Women, Neetu Abad, Monique Carry, Jeffrey H. Herbst, Catherine I. Fogel Oct 2013

Motivation To Reduce Risk Behaviors While In Prison: Qualitative Analysis Of Interviews With Current And Formerly Incarcerated Women, Neetu Abad, Monique Carry, Jeffrey H. Herbst, Catherine I. Fogel

Qualitative Criminology (QC)

"Prison is an environment in which programs can be implemented to change harmful behaviors among high-risk populations. Incarcerated women experience high rates of HIV and other sexually transmitted diseases (STDs), yet little research has examined women’s motivation to reduce risky behaviors during incarceration. In-depth individual interviews were conducted with former and current women prisoners in two North Carolina correctional facilities and analyzed to identify barriers and facilitators of behavior change while in prison. Analyses revealed key motivators of behavior change: Viewing prison as a place to recover from past trauma, removing oneself from negative social networks, gaining access to needed …


Sylvatic Species Of Echinococcus From Rodent Intermediate Hosts In Asia And South America, Scott Lyell Gardner, Altangerel T. Dursahinhan, Gábor R. Rácz, Nyamsuren Batsaikhan, Sumiya Ganzorig, David S. Tinnin, Darmaa Damdinbazar, Charles Wood, A. Townsend Peterson, Erika Alandia, José Luís Mollericona, Jorge Salazar-Bravo Oct 2013

Sylvatic Species Of Echinococcus From Rodent Intermediate Hosts In Asia And South America, Scott Lyell Gardner, Altangerel T. Dursahinhan, Gábor R. Rácz, Nyamsuren Batsaikhan, Sumiya Ganzorig, David S. Tinnin, Darmaa Damdinbazar, Charles Wood, A. Townsend Peterson, Erika Alandia, José Luís Mollericona, Jorge Salazar-Bravo

Harold W. Manter Laboratory of Parasitology: Faculty Publications

During a global survey of the diversity of vertebrates and their parasites including the Gobi and desert/steppe biomes ranging from south central to western Mongolia, we found metacestodes (larvae) of Echinococcus multilocularis (Leuckart 1863) in the liver of an individual vole (Microtus limnophilus Büchner 1889) collected in grassland habitat at Har Us Lake, southeast of Hovd, Mongolia. Positive identification of E. multilocularis from near Hovd was made via comparative cyst morphology, study of hooks from the rostellum derived from protoscolexes, and DNA sequencing of the COX1 mitochondrial gene extracted from tissue of the cysts frozen in the field. This …


Pritchardia Boliviensis N. Gen., N. Sp. (Anoplocephalidae: Linstowinae), A Tapeworm From Opossums (Didelphidae) In The Yungas And Lowlands Of Bolivia And Atlantic Forest Of Paraguay, Scott Lyell Gardner, F. Agustín Jiménez Ruiz, Mariel L. Campbell Oct 2013

Pritchardia Boliviensis N. Gen., N. Sp. (Anoplocephalidae: Linstowinae), A Tapeworm From Opossums (Didelphidae) In The Yungas And Lowlands Of Bolivia And Atlantic Forest Of Paraguay, Scott Lyell Gardner, F. Agustín Jiménez Ruiz, Mariel L. Campbell

Harold W. Manter Laboratory of Parasitology: Faculty Publications

Pritchardia boliviensis n. gen. n. sp. (Anoplocephalidae: Linstowiinae) is described from marsupials (Marmosops noctivagus, Metachirus nudicaudatus, Gracilinanus sp.) collected in Bolivia and Paraguay. These cestodes have a very small strobila with only three segments, regularly alternating genital pores, genital ducts crossing excretory canals ventrally, ovoid to pyriform cirrus sac, three to five testes, external seminal vesicle present and separated from cirrus sac by long seminal duct surrounded by glandular material, uterus ephemeral, eggs forming rapidly in gravid segments, and seminal receptacle present. Pritchardia boliviensis n. sp. includes a single species that occurs in small marsupials in the family …


A Framework To Evaluate Wildlife Feeding In Research, Wildlife Management, Tourism And Recreation, Sara Dubois, David Fraser Oct 2013

A Framework To Evaluate Wildlife Feeding In Research, Wildlife Management, Tourism And Recreation, Sara Dubois, David Fraser

Wildlife Population Management Collection

Feeding of wildlife occurs in the context of research, wildlife management, tourism and in opportunistic ways. A review of examples shows that although feeding is often motivated by good intentions, it can lead to problems of public safety and conservation and be detrimental to the welfare of the animals. Examples from British Columbia illustrate the problems (nuisance animal activity, public safety risk) and consequences (culling, translocation) that often arise from uncontrolled feeding. Three features of wildlife feeding can be distinguished: the feasibility of control, the effects on conservation and the effects on animal welfare. An evaluative framework incorporating these three …


Mycological Study For A Management Plan Of A Neotropical Show Cave (Brazil), Erika Linzi Silva Taylor, Maria Aparecida De Resende Stoianoff, Rodrigo Lopes Ferreira Oct 2013

Mycological Study For A Management Plan Of A Neotropical Show Cave (Brazil), Erika Linzi Silva Taylor, Maria Aparecida De Resende Stoianoff, Rodrigo Lopes Ferreira

International Journal of Speleology

Caves are stable environments with characteristics favoring the development of microorganisms. The allocthonous input of organic matter and microbes into the warm Neotropical caves may favor the development of filamentous fungi, including pathogenic species. Histoplasma capsulatum is a pathogenic species commonly found in caves and associated with bat and bird guano. Many Brazilian caves have been historically visited due to scenic and religious tourism. The objective of this study was to perform a microbiology study for a management plan of a show cave in Brazil, focusing on the presence and distribution of pathogenic and opportunistic fungi in the cave. Statistics …


Shaken Baby Syndrome, Wrongful Convictions, And The Dangers Of Aversion To Changing Science In Criminal Law, Cassandra Ann Jenecke Oct 2013

Shaken Baby Syndrome, Wrongful Convictions, And The Dangers Of Aversion To Changing Science In Criminal Law, Cassandra Ann Jenecke

University of San Francisco Law Review

No abstract provided.


Snapin, Positive Regulator Of Stimulation- Induced Ca(2+) Release Through Ryr, Is Necessary For Hiv-1 Replication In T Cells., Shigemi M Kinoshita, Amane Kogure, Shizuka Taguchi, Garry P Nolan Oct 2013

Snapin, Positive Regulator Of Stimulation- Induced Ca(2+) Release Through Ryr, Is Necessary For Hiv-1 Replication In T Cells., Shigemi M Kinoshita, Amane Kogure, Shizuka Taguchi, Garry P Nolan

Department of Microbiology and Immunology Faculty Papers

To identify critical host factors necessary for human immunodeficiency virus 1 (HIV-1) replication, large libraries of short-peptide-aptamers were expressed retrovirally. The target of one inhibitor peptide, Pep80, identified in this screen was determined to be Snapin, a protein associated with the soluble N-ethyl maleimide sensitive factor adaptor protein receptor (SNARE) complex that is critical for calcium-dependent exocytosis during neurotransmission. Pep80 inhibited Ca(2+) release from intracellular stores and blocked downstream signaling by direct interruption of the association between Snapin and an intracellular calcium release channel, the ryanodine receptor (RyR). NFAT signaling was preferentially abolished by Pep80. Expression of Snapin overcame Pep80-mediated …


Community Water Fluoridation Around The Nation: Significant Case Law And Legislation, Jeff Wurzburg, Corrine Propas Parver Oct 2013

Community Water Fluoridation Around The Nation: Significant Case Law And Legislation, Jeff Wurzburg, Corrine Propas Parver

Health Law and Policy Brief

No abstract provided.


State Obligations To Guarantee The Human Right To Health And The Derivative Right To Access Medicines, Ophelie Garnier, Chelsea Masters, Natassia Rozario, Mina Trudeau Oct 2013

State Obligations To Guarantee The Human Right To Health And The Derivative Right To Access Medicines, Ophelie Garnier, Chelsea Masters, Natassia Rozario, Mina Trudeau

Health Law and Policy Brief

No abstract provided.


An Assessment Of Hepatitis E Virus (Hev) In Us Blood Donors And Recipients: No Detectable Hev Rna In 1939 Donors Tested And No Evidence For Hev Transmission To 362 Prospectively Followed Recipients., Chenyu Xu, Richard Y. Wang, Cathy A. Schechterly, Shengxiang Ge, James W. Shih, Ning-Shao Xia, Naomi L. Luban, Harvey J. Alter Oct 2013

An Assessment Of Hepatitis E Virus (Hev) In Us Blood Donors And Recipients: No Detectable Hev Rna In 1939 Donors Tested And No Evidence For Hev Transmission To 362 Prospectively Followed Recipients., Chenyu Xu, Richard Y. Wang, Cathy A. Schechterly, Shengxiang Ge, James W. Shih, Ning-Shao Xia, Naomi L. Luban, Harvey J. Alter

Pediatrics Faculty Publications

BACKGROUND:

Hepatitis E virus (HEV) infection has become relevant to blood transfusion practice because isolated cases of blood transmission have been reported and because HEV has been found to cause chronic infection and severe liver disease in immunocompromised patients.

STUDY DESIGN AND METHODS:

We tested for immunoglobulin (Ig)G and IgM antibodies to the HEV and for HEV RNA in 1939 unselected volunteer US blood donors. Subsequently, we tested the same variables in pre- and serial posttransfusion samples from 362 prospectively followed blood recipients to assess transfusion risk.

RESULTS:

IgG anti-HEV seroprevalence in the total 1939 donations was 18.8%: 916 of …


A Cross-Cultural Health Care Approach To Improve Veteran Health Services In An Academic Community Hospital, Judith Sabino Mph, Eric Johnson Mpsa, Cps, Caama, Chs, Chep, Cdp, James F. Geiger Mpa, Fache Oct 2013

A Cross-Cultural Health Care Approach To Improve Veteran Health Services In An Academic Community Hospital, Judith Sabino Mph, Eric Johnson Mpsa, Cps, Caama, Chs, Chep, Cdp, James F. Geiger Mpa, Fache

Administration & Leadership

No abstract provided.


Trauma History And Depression Predict Incomplete Adherence To Antiretroviral Therapies In A Low Income Country, Kathryn Whetten, Kristen Shirey, Brian Wells Pence, Jia Yao, Nathan Thielman, Rachel Whetten, Julie Adams, Bernard Agala, Jan Ostermann, Karen O'Donnell, Amy Hobbie, Venance Maro, Dafrosa Itemba, Elizabeth Reddy, Chat Research Team Oct 2013

Trauma History And Depression Predict Incomplete Adherence To Antiretroviral Therapies In A Low Income Country, Kathryn Whetten, Kristen Shirey, Brian Wells Pence, Jia Yao, Nathan Thielman, Rachel Whetten, Julie Adams, Bernard Agala, Jan Ostermann, Karen O'Donnell, Amy Hobbie, Venance Maro, Dafrosa Itemba, Elizabeth Reddy, Chat Research Team

Faculty Publications

Background: As antiretroviral therapy (ART) for HIV becomes increasingly available in low and middle income countries (LMICs), understanding reasons for lack of adherence is critical to stemming the tide of infections and improving health. Understanding the effect of psychosocial experiences and mental health symptomatology on ART adherence can help maximize the benefit of expanded ART programs by indicating types of services, which could be offered in combination with HIV care. Methodology: The Coping with HIV/AIDS in Tanzania (CHAT) study is a longitudinal cohort study in the Kilimanjaro Region that included randomly selected HIV-infected (HIV+) participants from two local hospital-based HIV …


Identification Of Leptospira Interrogans Phospholipase C As A Novel Virulence Factor Responsible For Intracellular Free Calcium Ion Elevation During Macrophage Death, Jing-Fang Zhao, Hong-Hu Chen, David M. Ojcius, Xin Zhao, Dexter Sun, Yu-Mei Ge, Lin-Li Zheng, Xu'ai Lin, Lan-Juan Li, Jie Yan Oct 2013

Identification Of Leptospira Interrogans Phospholipase C As A Novel Virulence Factor Responsible For Intracellular Free Calcium Ion Elevation During Macrophage Death, Jing-Fang Zhao, Hong-Hu Chen, David M. Ojcius, Xin Zhao, Dexter Sun, Yu-Mei Ge, Lin-Li Zheng, Xu'ai Lin, Lan-Juan Li, Jie Yan

All Dugoni School of Dentistry Faculty Articles

Background: Leptospira-induced macrophage death has been confirmed to play a crucial role in pathogenesis of leptospirosis, a worldwide zoonotic infectious disease. Intracellular free Ca2+ concentration ([Ca2+]i) elevation induced by infection can cause cell death, but [Ca2+]i changes and high [Ca2+]i-induced death of macrophages due to infection of Leptospira have not been previously reported.

Methodology/Principal Findings: We first used a Ca2+-specific fluorescence probe to confirm that the infection of L. interrogans strain Lai triggered a significant increase of [Ca2+]i in mouse J774A.1 or human THP-1 macrophages. Laser confocal microscopic examination …


Addressing The Health Of Hispanic Migrant Farmworkers In Rural East Tennessee Through Interprofessional Education, Experiential Learning, And A University/Community Partnership, Sharon Loury, Mchael Bradfield, Joseph Florence, Kenneth Silver, Karin Hoffman, Alexis Andino Oct 2013

Addressing The Health Of Hispanic Migrant Farmworkers In Rural East Tennessee Through Interprofessional Education, Experiential Learning, And A University/Community Partnership, Sharon Loury, Mchael Bradfield, Joseph Florence, Kenneth Silver, Karin Hoffman, Alexis Andino

International Journal of Health Sciences Education

The concept of interprofessional practice and education is not new but has recently gained attention as the result of a paradigm shift in the future of healthcare and how it is delivered and financed. Universities are now addressing ways to incorporate interprofessional education and learning experiences into the curriculum to ensure graduating healthcare professionals are competent to collaborate as a team and deliver quality effective healthcare.

A regional research university in East Tennessee with health programs across five Health Science colleges (Clinical and Rehabilitative Health Sciences, Medicine, Nursing, Pharmacy, and Public Health), Psychology, and Social Work has offered an interprofessional …