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2013

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Complementarity In Public Health Systems: Using Redundancy As A Tool Of Public Health Governance, Lance Gable, Benjamin Mason Meier Jan 2013

Complementarity In Public Health Systems: Using Redundancy As A Tool Of Public Health Governance, Lance Gable, Benjamin Mason Meier

Law Faculty Research Publications

No abstract provided.


The Potent And Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1c19 Reveals A Unique Cross-Reactive Epitope On The Bc Loop Of Domain Ii Of The Envelope Protein, Scott A. Smith, A. Ruklanthi De Alwis, Nurgun Kose, Eva Harris, Kristie D. Ibarra, Kristen M. Kahle, Jennifer M. Pfaff, Xiaoxiao Xiang, Benjamin J. Doranz, Aravinda M. De Silva, S. Kyle Austin, Soila Sukupolvi-Petty, Michael S. Diamond, James E. Crowe Jr. Jan 2013

The Potent And Broadly Neutralizing Human Dengue Virus-Specific Monoclonal Antibody 1c19 Reveals A Unique Cross-Reactive Epitope On The Bc Loop Of Domain Ii Of The Envelope Protein, Scott A. Smith, A. Ruklanthi De Alwis, Nurgun Kose, Eva Harris, Kristie D. Ibarra, Kristen M. Kahle, Jennifer M. Pfaff, Xiaoxiao Xiang, Benjamin J. Doranz, Aravinda M. De Silva, S. Kyle Austin, Soila Sukupolvi-Petty, Michael S. Diamond, James E. Crowe Jr.

Open Access Publications

No abstract provided.


Development Of A Highly Protective Combination Monoclonal Antibody Therapy Against Chikungunya Virus, Pankaj Pal, Kimberly A. Dowd, James D. Brien, Melissa A. Edeling, Sergey Gorlatov, Syd Johnson, Iris Lee, Wataru Akahata, Gary J. Nabel, Mareike K. S. Richter, Jolanda M. Smit, Daved H. Fremont, Theodore C. Pierson, Mark T. Heise, Michael S. Diamond Jan 2013

Development Of A Highly Protective Combination Monoclonal Antibody Therapy Against Chikungunya Virus, Pankaj Pal, Kimberly A. Dowd, James D. Brien, Melissa A. Edeling, Sergey Gorlatov, Syd Johnson, Iris Lee, Wataru Akahata, Gary J. Nabel, Mareike K. S. Richter, Jolanda M. Smit, Daved H. Fremont, Theodore C. Pierson, Mark T. Heise, Michael S. Diamond

Open Access Publications

No abstract provided.


Blockade Ofthe Negative Co-Stimulatory Molecules Pd-1 And Ctla-4 Improves Survival In Primary And Secondary Fungal Sepsis, Katherine C. Chang, Carey-Ann Burnham, Stephanie M. Compton, David P. Rasche, Richard J. Mazuski, Jacquelyn S. Mcdonough, Jacqueline Unsinger, Alan J. Korman, Jonathan M. Green, Richard S. Hotchkiss Jan 2013

Blockade Ofthe Negative Co-Stimulatory Molecules Pd-1 And Ctla-4 Improves Survival In Primary And Secondary Fungal Sepsis, Katherine C. Chang, Carey-Ann Burnham, Stephanie M. Compton, David P. Rasche, Richard J. Mazuski, Jacquelyn S. Mcdonough, Jacqueline Unsinger, Alan J. Korman, Jonathan M. Green, Richard S. Hotchkiss

Open Access Publications

No abstract provided.


Structural Analyses At Pseudo Atomic Resolution Of Chikungunya Virus And Antibodies Show Mechanisms Of Neutralization, Siyang Sun, Ye Xiang, Wataru Akahata, Heather Holdaway, Pankaj Pal, Xinzheng Zhang, Michael S. Diamond, Gary J. Nabel Jan 2013

Structural Analyses At Pseudo Atomic Resolution Of Chikungunya Virus And Antibodies Show Mechanisms Of Neutralization, Siyang Sun, Ye Xiang, Wataru Akahata, Heather Holdaway, Pankaj Pal, Xinzheng Zhang, Michael S. Diamond, Gary J. Nabel

Open Access Publications

No abstract provided.


Sex-Stratified Genome-Wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism In Genetic Loci For Anthropometric Traits, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province, Et Al Jan 2013

Sex-Stratified Genome-Wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism In Genetic Loci For Anthropometric Traits, Mary F. Feitosa, Aldi T. Kraja, Michael A. Province, Et Al

Open Access Publications

No abstract provided.


Cytosolic Phospholipasea2 Inhibition With Pla-695 Radiosensitizes Tumors In Lung Cancer Animal Models, Dinesh Thotala, Jeffrey M. Craft, Daniel J. Ferraro, Rama P. Kotipatruni, Sandeep R. Bhave, Jerry J. Jaboin, Dennis E. Hallahan Jan 2013

Cytosolic Phospholipasea2 Inhibition With Pla-695 Radiosensitizes Tumors In Lung Cancer Animal Models, Dinesh Thotala, Jeffrey M. Craft, Daniel J. Ferraro, Rama P. Kotipatruni, Sandeep R. Bhave, Jerry J. Jaboin, Dennis E. Hallahan

Open Access Publications

No abstract provided.


Cache Valley Virus In A Patient Diagnosed With Aseptic Meningitis, Nang L. Nguyen, Guoyan Zhao, Rene Hull, Mark A. Shelly, Susan J. Wong, Guang Wu, Kirsten St. George, David Wang, Marilyn A. Menegus Jan 2013

Cache Valley Virus In A Patient Diagnosed With Aseptic Meningitis, Nang L. Nguyen, Guoyan Zhao, Rene Hull, Mark A. Shelly, Susan J. Wong, Guang Wu, Kirsten St. George, David Wang, Marilyn A. Menegus

Open Access Publications

No abstract provided.


Myxomavirus-Derived Serpin Prolongs Survival And Reduces Inflammation And Hemorrhage In An Unrelated Lethal Mouse Viral Infection, Herbert W. Virgin, Et Al Jan 2013

Myxomavirus-Derived Serpin Prolongs Survival And Reduces Inflammation And Hemorrhage In An Unrelated Lethal Mouse Viral Infection, Herbert W. Virgin, Et Al

Open Access Publications

No abstract provided.


A Successful Strategy For Increasing The Influenza Vaccination Rate Of Healthcare Workers Without A Mandatory Policy Outside Of The United States: A Multifaceted Intervention In A Japanese Tertiary Care Center, Hitoshi Honda, Yumiko Sato, Akinori Yamazaki, Simi Padival, Akira Kumagai, Hilary Babcock Jan 2013

A Successful Strategy For Increasing The Influenza Vaccination Rate Of Healthcare Workers Without A Mandatory Policy Outside Of The United States: A Multifaceted Intervention In A Japanese Tertiary Care Center, Hitoshi Honda, Yumiko Sato, Akinori Yamazaki, Simi Padival, Akira Kumagai, Hilary Babcock

Open Access Publications

No abstract provided.


Coreceptor Affinity For Mhc Defines Peptide Specificity Requirements For Tcr Interaction With Coagonist Peptide–Mhc, John A H Hoerter, Joanna Brzostek, Maxim N. Artyomov, Steven M. Abel, Javier Casas, Vasily Rybakin, Jeanette Ampudia, Carina Lotz, Janet M. Connolly, Arup K. Chakraborty, Keith G. Gould, Nicholas R J Gascoigne Jan 2013

Coreceptor Affinity For Mhc Defines Peptide Specificity Requirements For Tcr Interaction With Coagonist Peptide–Mhc, John A H Hoerter, Joanna Brzostek, Maxim N. Artyomov, Steven M. Abel, Javier Casas, Vasily Rybakin, Jeanette Ampudia, Carina Lotz, Janet M. Connolly, Arup K. Chakraborty, Keith G. Gould, Nicholas R J Gascoigne

Open Access Publications

No abstract provided.


Discontinuation Of Reflex Testing Of Stool Samples For Vancomycin-Resistant Enterococci Resulted In Increased Prevalence, Mandy Bodily, Kathleen M. Mcmullen, Anthony J. Russo, Nupur D. Kittur, Joan Hoppe-Bauer, David K. Warren Jan 2013

Discontinuation Of Reflex Testing Of Stool Samples For Vancomycin-Resistant Enterococci Resulted In Increased Prevalence, Mandy Bodily, Kathleen M. Mcmullen, Anthony J. Russo, Nupur D. Kittur, Joan Hoppe-Bauer, David K. Warren

Open Access Publications

No abstract provided.


Discovery Of Anthelmintic Drug Targets And Drugs Using Chokepoints In Nematode Metabolic Pathways, Christina M. Taylor, Qi Wang, Bruce A. Rosa, Stanley Ching-Cheng Huang, Kerrie Powell, Tim Schedl, Edward J. Pearce, Sahar Abubucker, Makedonka Mitreva Jan 2013

Discovery Of Anthelmintic Drug Targets And Drugs Using Chokepoints In Nematode Metabolic Pathways, Christina M. Taylor, Qi Wang, Bruce A. Rosa, Stanley Ching-Cheng Huang, Kerrie Powell, Tim Schedl, Edward J. Pearce, Sahar Abubucker, Makedonka Mitreva

Open Access Publications

No abstract provided.


Prevalence And Predictors Of Compliance With Discontinuation Of Airborne Isolation In Patients With Suspected Pulmonary Tuberculosis, Benjamin S. Thomas, Erlaine F. Bello, Todd B. Seto Jan 2013

Prevalence And Predictors Of Compliance With Discontinuation Of Airborne Isolation In Patients With Suspected Pulmonary Tuberculosis, Benjamin S. Thomas, Erlaine F. Bello, Todd B. Seto

Open Access Publications

No abstract provided.


Genome Sequences Of Three Hpafrica2 Strains Of Helicobacter Pylori, Stacy S. Duncan, M Teresita Bertoli, Dangeruta Kersulyte, Pieter L. Valk, Sravya Tamma, Issy Segal, Mark S. Mcclain, Timothy L. Cover, Douglas E. Berg Jan 2013

Genome Sequences Of Three Hpafrica2 Strains Of Helicobacter Pylori, Stacy S. Duncan, M Teresita Bertoli, Dangeruta Kersulyte, Pieter L. Valk, Sravya Tamma, Issy Segal, Mark S. Mcclain, Timothy L. Cover, Douglas E. Berg

Open Access Publications

No abstract provided.


Using Existing Drugs As Leads For Broad Spectrum Anthelmintics Targeting Protein Kinases, Christina M. Taylor, John Martin, Ramakrishna U. Rao, Kerrie Powell, Sahar Abubucker, Makedonka Mitreva Jan 2013

Using Existing Drugs As Leads For Broad Spectrum Anthelmintics Targeting Protein Kinases, Christina M. Taylor, John Martin, Ramakrishna U. Rao, Kerrie Powell, Sahar Abubucker, Makedonka Mitreva

Open Access Publications

No abstract provided.


Clinical Features Of Bacterial Vaginosis In A Murine Model Of Vaginal Infection With Gardnerella Vaginalis, Nicole M. Gilbert, Warren G. Lewis, Amanda L. Lewis Jan 2013

Clinical Features Of Bacterial Vaginosis In A Murine Model Of Vaginal Infection With Gardnerella Vaginalis, Nicole M. Gilbert, Warren G. Lewis, Amanda L. Lewis

Open Access Publications

No abstract provided.


Protection By Immunoglobulin Dual-Affinity Retargeting Antibodies Against Dengue Virus, James D. Brien, Soila Sukupolvi-Petty, Katherine L. Williams, Chia-Ying Kao Lam, Michael A. Schmid, Syd Johnson, Eva Harris, Michael S. Diamond Jan 2013

Protection By Immunoglobulin Dual-Affinity Retargeting Antibodies Against Dengue Virus, James D. Brien, Soila Sukupolvi-Petty, Katherine L. Williams, Chia-Ying Kao Lam, Michael A. Schmid, Syd Johnson, Eva Harris, Michael S. Diamond

Open Access Publications

No abstract provided.


Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-Mediated Neuronal Responses That Are Cytoprotective, Interferon Independent, And Inhibited By Western Equine Encephalitis Virus Capsid, Daniel C. Peltier, Helen M. Lazear, Jocelyn R. Farmer, Michael S. Diamond, David J. Miller Jan 2013

Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-Mediated Neuronal Responses That Are Cytoprotective, Interferon Independent, And Inhibited By Western Equine Encephalitis Virus Capsid, Daniel C. Peltier, Helen M. Lazear, Jocelyn R. Farmer, Michael S. Diamond, David J. Miller

Open Access Publications

No abstract provided.


Developing A New, National Approach To Surveillance For Ventilator-Associated Events: Executive Summary, Marin Kollef, Shelley S. Magill, Michael Klompas, Robert Balk, Suzanne M. Burns, Clifford S. Deutschman, Daniel Diekema, Scott Fridkin, Linda Greene, Alice Guh, David Gutterman, Beth Hammer, David Henderson, Dean R. Hess Jan 2013

Developing A New, National Approach To Surveillance For Ventilator-Associated Events: Executive Summary, Marin Kollef, Shelley S. Magill, Michael Klompas, Robert Balk, Suzanne M. Burns, Clifford S. Deutschman, Daniel Diekema, Scott Fridkin, Linda Greene, Alice Guh, David Gutterman, Beth Hammer, David Henderson, Dean R. Hess

Open Access Publications

No abstract provided.


Optimization Of Routine Identification Of Clinically Relevant Gram-Negative Bacteria By Use Of Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry And The Bruker Biotyper, Bradley A. Ford, Carey-Ann D. Burnham Jan 2013

Optimization Of Routine Identification Of Clinically Relevant Gram-Negative Bacteria By Use Of Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry And The Bruker Biotyper, Bradley A. Ford, Carey-Ann D. Burnham

Open Access Publications

No abstract provided.


The Absence Of Myocardial Calcium-Independent Phospholipase A2Γ Results In Impaired Prostaglandin E2 Production And Decreased Survival In Mice With Acute Trypanosoma Cruzi Infection, Janhavi Sharma, Christopher S. Eickhoff, Daniel F. Hoft, David A. Ford, Richard W. Gross, Jane Mchowat Jan 2013

The Absence Of Myocardial Calcium-Independent Phospholipase A2Γ Results In Impaired Prostaglandin E2 Production And Decreased Survival In Mice With Acute Trypanosoma Cruzi Infection, Janhavi Sharma, Christopher S. Eickhoff, Daniel F. Hoft, David A. Ford, Richard W. Gross, Jane Mchowat

Open Access Publications

No abstract provided.


A Colanic Acid Operon Deletion Mutation Enhances Induction Of Early Antibody Responses By Live Attenuated Salmonella Vaccine Strains, Shifeng Wang, Huoying Shi, Yuhua Li, Zhaoxing Shi, Xin Zhang, Chang-Ho Baek, Tabor Mothershead, Roy Curtiss Iii Jan 2013

A Colanic Acid Operon Deletion Mutation Enhances Induction Of Early Antibody Responses By Live Attenuated Salmonella Vaccine Strains, Shifeng Wang, Huoying Shi, Yuhua Li, Zhaoxing Shi, Xin Zhang, Chang-Ho Baek, Tabor Mothershead, Roy Curtiss Iii

Open Access Publications

No abstract provided.


Estrogenic Modulation Of Uropathogenic Escherichia Coli Infection Pathogenesis In A Murine Menopause Model, Caihong Wang, Jane W. Symington, Emily Ma, Indira U. Mysorekar Jan 2013

Estrogenic Modulation Of Uropathogenic Escherichia Coli Infection Pathogenesis In A Murine Menopause Model, Caihong Wang, Jane W. Symington, Emily Ma, Indira U. Mysorekar

Open Access Publications

No abstract provided.


Sequence Divergence And Conservation In Genomes Of Helicobacter Cetorum Strains From A Dolphin And A Whale, Dangeruta Kersulyte, Mirko Rossi, Douglas E. Berg Jan 2013

Sequence Divergence And Conservation In Genomes Of Helicobacter Cetorum Strains From A Dolphin And A Whale, Dangeruta Kersulyte, Mirko Rossi, Douglas E. Berg

Open Access Publications

No abstract provided.


Atg5 Regulates Plasma Cell Differentiation, Kara L. Conway, Petric Kuballa, Bernard Khor, Mei Zhang, Hai Ning Shi, Herbert W. Virgin, Ramnik J. Xavier Jan 2013

Atg5 Regulates Plasma Cell Differentiation, Kara L. Conway, Petric Kuballa, Bernard Khor, Mei Zhang, Hai Ning Shi, Herbert W. Virgin, Ramnik J. Xavier

Open Access Publications

No abstract provided.


Political Violence, Collective Functioning And Health: A Review Of The Literature, Cindy A. Sousa Jan 2013

Political Violence, Collective Functioning And Health: A Review Of The Literature, Cindy A. Sousa

Graduate School of Social Work and Social Research Faculty Research and Scholarship

Political violence is implicated in a range of mental health outcomes, including PTSD, depression, and anxiety. The social and political contexts of people’s lives, however, offer considerable protection from the mental health effects of political violence. In spite of the importance of people’s social and political environments for health, there is limited scholarship on how political violence compromises necessary social and political systems and inhibits individuals from participating in social and political life. Drawing on literature from multiple disciplines, including public health, anthropology, and psychology, this narrative review uses a multi-level, social ecological framework to enhance current knowledge about the …


The Effect Of Vitamin D On Human T Regulatory Cell Differentiation, Stephanie Anne Chapman Jan 2013

The Effect Of Vitamin D On Human T Regulatory Cell Differentiation, Stephanie Anne Chapman

Master's Theses

Regulatory T cells (Tregs) are required for the induction and maintenance of immune homeostasis. Singh et al. demonstrated that depletion of Tregs in mice results in a loss of self-tolerance that manifests in the development of autoimmune diseases such as Inflammatory Bowel Disease (IBD). In humans, autoimmune diseases such as IBD, Multiple Sclerosis (MS), and Type 1 Diabetes are thought to occur due to a deficiency in the number or function of Tregs. The importance of Tregs in modulating the human immune system is perhaps best exemplified by IPEX (immune dysregulation, polyendocrinopathy, enteropathy, x-linked syndrome), a severe autoimmune disease characterized …


Use Of Ethanol Extract Of Mycobacterium Bovis For Detection Of Specific Antibodies In Sera Of Farmed Red Deer (Cervus Elaphus) With Bovine Tuberculosis, Ashutosh Wadhwa, Rachel E. Johnson, C. G. Mackintosh, J Frank Griffin, W Ray Waters, John Bannantine, Shigetoshi Eda Jan 2013

Use Of Ethanol Extract Of Mycobacterium Bovis For Detection Of Specific Antibodies In Sera Of Farmed Red Deer (Cervus Elaphus) With Bovine Tuberculosis, Ashutosh Wadhwa, Rachel E. Johnson, C. G. Mackintosh, J Frank Griffin, W Ray Waters, John Bannantine, Shigetoshi Eda

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Background: Bovine tuberculosis (bTB) in wildlife species poses a threat to domestic livestock in many situations. Control programs for bTB in livestock depend on testing and slaughtering the positive animals; however, the currently available diagnostic tests often have poor specificity. In our previous study, we developed a specific and sensitive enzyme linked immunosorbent assay (ELISA) for another mycobacterial disease – Johne’s disease, using surface antigens of Mycobacterium avium ssp. paratuberculosis (MAP) extracted by briefly agitating the bacilli in 80% ethanol solution. The ELISA test was named ethanol vortex ELISA (EVELISA). The objective of this study is to examine whether EVELISA …


High-Impact Animal Health Research Conducted At The Usda’S National Animal Disease Center, J. P. Bannantine, Steven C. Olsen, Marcus E. Kehrli Jr., Thad B. Stanton, Eduardo Casas, Diana L. Whipple, Kurt A. Zuelke Jan 2013

High-Impact Animal Health Research Conducted At The Usda’S National Animal Disease Center, J. P. Bannantine, Steven C. Olsen, Marcus E. Kehrli Jr., Thad B. Stanton, Eduardo Casas, Diana L. Whipple, Kurt A. Zuelke

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Commissioned by President Dwight Eisenhower in 1958 and opened with a dedication ceremony in December 1961, the USDA, Agricultural Research Service (ARS), National Animal Disease Center (NADC) celebrated its 50-year anniversary in November 2011. Over these 50 years, the NADC established itself among the world’s premier animal health research centers. Its historic mission has been to conduct basic and applied research on selected endemic diseases of economic importance to the U.S. livestock and poultry industries. Research from NADC has impacted control or management efforts on nearly every major animal disease in the United States since 1961. For example, diagnostic tests …