Digital Commons Network^™

Uncertainty In Population Estimates For Endangered Animals And Improving The Recovery Process, Dale D. Goble

Articles

United States recovery plans contain biological information for a species listed under the Endangered Species Act and specify recovery criteria to provide basis for species recovery. The objective of our study was to evaluate whether recovery plans provide uncertainty (e.g., variance) with estimates of population size. We reviewed all finalized recovery plans for listed terrestrial vertebrate species to record the following data: (1) if a current population size was given, (2) if a measure of uncertainty or variance was associated with current estimates of population size and (3) if population size was stipulated for recovery. We found that 59% of …

Substituent Effects On Reactivity And Allergenicity Of Benzoquinone, Wilbes Mbiya

Dissertations and Theses

Benzoquinone (BQ) is an extremely potent electrophilic contact allergen that haptenates endogenous proteins through Michael addition (MA). It is also hypothesized that BQ may haptenate proteins via free radical formation. The objective of this study was to assess the inductive effects (activating and deactivating) of substituents on BQ reactivity and the mechanistic pathway of covalent binding to nucleophilic thiols. The BQ binding by Cys34 on human serum albumin was studied, and for reactivity studies, nitrobenzenethiol (NBT) was used as a surrogate for protein binding of the BQ and benzoquinone derivatives (BQD). Stopped flow techniques were used to determine pseudo-first order …

The Efficacy Of Using Animal-Assisted Therapy To Decrease Maladaptive Behaviors In Children With Reactive Attachment Disorder, Trisha Markle, Dr. Gary Burlingame

Journal of Undergraduate Research

This study is currently still in progress. We are in the final stages of a pilot study that was supported by this ORCA grant. A new and funded version of the study will begin in January based upon the findings of the pilot. As noted in our IRB, our pilot study was conducted as a quality improvement project at Utah State hospital (USH).

Effects Of Chronic Alcohol Intoxication On The Dopaminergic Reward Pathway, Brian Hoyt, Dr. Scott Steffensen

Journal of Undergraduate Research

My research project studied the effects of chronic alcohol intoxication on the brain’s pleasure center (the mesocorticolimbic system). I worked with JungJae Park (M.S. in neuroscience) and three other undergraduate students. Because rats dislike the taste of alcohol, we injected the alcohol directly into their abdominal cavity. This was done under isoflourane anesthesia to avoid any discomfort for the animals. We injected three experimental rats an intoxicating dose of alcohol twice daily for three weeks. Three other rats were used as control subjects (received saline injections twice daily).

Reader's Theater For Deaf Students: A Tool For Developing Literacy Skills, Caroline Suggs

Undergraduate University Honors Capstones

Reader's theater is a method used in classrooms to encourage the development of literacy skills. Research has shown that the use of reader's theater in a classroom is linked to increased fluency, increased comprehension of text, and positive attitudes towards reading. Because research also shows that Deaf people are often delayed regarding literacy in English, a unit employing this method serves to bridge the gap between expected and actual levels of English literacy among deaf students. Intended for use with Deaf middle school students who sign, this unit of reader's theater is a plausible option in a bilingual approach since …

Jellyfish Body Plans Provide Allometric Advantages Beyond Low Carbon Content, Kylie A. Pitt, Carlos M. Duarte, Cathy H. Lucas, Kelly R. Sutherland, Robert H. Condon, Hermes Mianzan, Jennifer E. Purcell, Kelly L. Robinson, Shin-Ichi Uye

Faculty Publications

Jellyfish form spectacular blooms throughout the world's oceans. Jellyfish body plans are characterised by high water and low carbon contents which enables them to grow much larger than non-gelatinous animals of equivalent carbon content and to deviate from non-gelatinous pelagic animals when incorporated into allometric relationships. Jellyfish have, however, been argued to conform to allometric relationships when carbon content is used as the metric for comparison. Here we test the hypothesis that differences in allometric relationships for several key functional parameters remain for jellyfish even after their body sizes are scaled to their carbon content. Data on carbon and nitrogen …

Novel Structural And Physiological Functions Of High Conductance K+ Channels Of The Slo Family, Gonzalo Budelli

All Theses and Dissertations (ETDs)

The SLO family channels are high conductance K+ channels that are gated both by voltage and intracellular ions. Structurally they resemble voltage gated channels but have additional large conserved intracellular domains appended on the C-terminal that allow them to be gated by different intracellular ions. Two members of this unique family of K+ channels are Slo1: BK) which is activated by Ca2+, and Slo2.2: Slack) which is activated by sodium. Both channels are widely expressed in the brain and other tissues in many species from C. elegans to humans.

The large conductance Ca2+- activated K+ channel: Slo1 or BK for …

Ccaat/Enhancer-Binding Protein Delta (C/Ebp-Delta) Expression In Antarctic Fishes: Implications For Cell Cycle And Apoptosis, Isaac Martin Sleadd

Dissertations and Theses

Chapter 1: Antarctic fishes are extremely cold adapted. Despite their inability to upregulate heat shock proteins, recent studies have demonstrated a capacity for heat response in these animals. A cDNA microarray study looked at the Notothenioid fish Trematomus bernacchii and revealed heat sensitivities for hundreds of genes, two of which code for members of the CCAAT/Enhancer-binding protein (C/EBP) family of transcription factors. These molecular switches are best known for their roles in apoptosis, inflammation and cell cycle arrest. This dissertation further elucidates the role of C/EBP-delta in the Antarctic fishes T. bernacchii and Pagothenia borchgrevinki.

Chapter 2: C/EBP-delta is constitutively …

Colour And Odour Drive Fruit Selection And Seed Dispersal By Mouse Lemurs, Kim Valenta, Ryan J. Burke, Sarah A. Styler, Derek A. Jackson, Amanda D. Melin, Shawn M. Lehman

Dartmouth Scholarship

Animals and fruiting plants are involved in a complex set of interactions, with animals relying on fruiting trees as food resources, and fruiting trees relying on animals for seed dispersal. This interdependence shapes fruit signals such as colour and odour, to increase fruit detectability, and animal sensory systems, such as colour vision and olfaction to facilitate food identification and selection. Despite the ecological and evolutionary importance of plant-animal interactions for shaping animal sensory adaptations and plant characteristics, the details of the relationship are poorly understood. Here we examine the role of fruit chromaticity, luminance and odour on seed dispersal by …

Homecoming, Posheng Chiang

Theses

A 30-minute narrative, based on a true story, Homecoming is about a journey of a family returning to Taiwan for father's funeral and disputing on the control with the uncle because of the cultural differences between Western (USA) and Eastern (Hakka). Through this event, Christian and Hakka conventions on death would be revealed, and reflects the spirits of life in two ways. However, the two generations would eventually find each other the common thing, the love of family. Pre-production of this overseas production happened in Rochester and Taiwan. The shoot was scheduled for 6 days in Taiwan only. The Budget …

Causes, Consequences, And Treatment Of Osteoporosis In Men, Jameela Banu

Health & Biomedical Sciences Faculty Publications

Men undergo gradual bone loss with aging, resulting in fragile bones. It is estimated that one in five men will suffer an osteoporotic fracture during their lifetime. The prognosis for men after a hip fracture is very grim. A major cause is reduction of free testosterone. Many other factors result in secondary osteoporosis, including treatment for other diseases such as cancer and diabetes. Patients should be screened not only for bone density but also assessed for their nutritional status, physical activity, and drug intake. Therapy should be chosen based on the type of osteoporosis. Available therapies include testosterone replacement, bisphosphonates, …

“Forty Years On: Women Lawyers? Still On That? And Ecofeminism . . . Again?”, Daniel M. Warner, Steven Hancher

Tennessee Journal of Race, Gender, & Social Justice

Forty years ago, environmentally concerned law students put hope for sustainability in two trends. First, the burgeoning number of women law-school students held promise: upon reaching professional stride in their forties and fifties (the late 1980s and 1990s), surely their influence would disabuse law and society of enough of its patriarchal, hierarchical domination—domination over nature here—to move society toward a new, sustainable course. Second—and related—the emerging philosophy of ecofeminism promised to call out the ecocrisis and push on with positive responses. But women never assumed influential roles in the important “big firms,” and ecofeminism lost focus and dissipated in a …

A Methodology For Appraisal And Validation Of User Centered Open Innovation Programs: A Case Study Critical Analysis Of An Energy Supplier Co-Creative Innovation Program, Américo Mateus, Ana Loureiro, Carlos Alves Rosa, Susana Leonor

Learn X Design Conference Series

Design thinking programs for innovation in accordance to a servicedominant logic (S-D logic) in co-creation with stakeholders is often described in the literature as an adequate procedure for added value and sustainability (Vargo & Webster, 2011; Mateus & Rosa, 2011; Ostrom et al., 2010; Brown, 2009; Vargo & Lusch, 2004, 2006, 2008a, 2008b). However, it seems to be absent from research robust validation methodologies. This article describes an empirically developed methodology for validation of design thinking Ideas(R) Evolution methodology applied to a User Centered Open Innovation Program for a more efficient behavior consumption of home energy. This program was developed …

Biofouling : A Means Of Aquatic Species Transfer, Anne Bouyssou, Josefin Madjidian

NSBWO

Ships carry seawater in their ballast tanks when they are not fully loaded with cargo, in order to maintain adequate trim, draught and stability, adjust list and limit stresses on the hull. It is now well documented that the water pumped into the ship contains aquatic organisms – which can also sink to the sediments at the bottom of tanks – and that these organisms are thereby transferred from the port of origin to the destination. But it is seldom mentioned that aquatic organisms are also found on the outside of ships, attached on their hulls and appendages, as a …

A Note On Pigs’ Knowledge Of Hidden Objects, Christian Nawroth, Mirjam Ebersbach, Eberhard Von Borell

Memory Collection

Object permanence is the notion that objects continue to exist even when they are out of observer’s sight. This ability is adaptive for free ranging animals who have to cope with a dangerous and highly changeable environment and allows them to be aware of predators sneaking in their proximity or to keep track of conspecifics or food sources, even when out of sight. Farm animals might also benefit from object permanence because the ability to follow the trajectory of hidden food or objects may lead to a higher predictability of subjects’ environment, which in turn might affect the level of …

Puppy Mill Closure: The Economic Impact On A Local Community, The Humane Society Of The United States

PUPPY MILL REPORTS

When a substandard dog-breeding facility (a puppy mill) closes, removing the dogs can drain the financial resources of a community, local animal welfare entities, and large humane organizations. Towns rarely derive any benefit from puppy mills, as they employ few staff, often don’t pay required taxes or license fees, generate much animal waste and pollution, and cause unpleasant odors and noise. Once a major puppy mill enterprise is discovered, many communities don’t have the necessary resources to handle the situation. Prevention is the key, and communities should discourage large scale breeding facilities from locating in their area.

Periphyton And Phytoplankton Chlorophyll A Levels In The Little Bear River And Hyrum Reservoir, Utah, Katie Fisher

Natural Resources and Environmental Issues

This study was conducted to assess the applicability of the River Continuum and Serial Discontinuity Concepts to the Little Bear River, using chlorophyll a values along the gradient of the river and within Hyrum Reservoir. Periphyton was analyzed from seven sites and phytoplankton from nine sites (including Hyrum Reservoir) in September 2012. The lower parts of the Little Bear River is heavily influenced by agricultural and anthropogenic sources of nutrients and other pollution, creating poor water quality in its lower reaches. Periphyton levels in the river increased along the gradient, peaking just below Hyrum reservoir, and then decreased with distance …

Algal Nutrient Limitation Throughout The Little Bear River Watershed, Jared Baker

Natural Resources and Environmental Issues

The objective of this study was to use a 5 day bioassay experiment to assess whether nitrogen or phosphorus limited the growth of algae in the Little Bear River watershed. Four sites were sampled along the river in September 2012. The locations of the sites were south of Avon (Station 2), near Paradise, UT (Station 6), downstream of Hyrum Reservoir (Station 7), and downstream of the Waste Water Treatment Facility in Wellsville (Station 10). Chlorophyll a analysis was conducted prior to, after 2.5 days, and at the conclusion of the 5 days. Varying combinations of nitrogen and phosphorus were added …

Ecomorphology And Mating Behavior Of Two Species Of Night-Stalking Tiger Beetles, Omus Audouini And O. Dejeanii, Robert Kent Richardson

Dissertations and Theses

Night-stalking tiger beetles (Cicindelinae: Omus) are among the least studied members of the highly diverse Carabid sub-family Cicindelinae, the tiger beetles. Despite populations of Omus being common in the forest floor habitats of the west coast of North America and their conspicuous predatory role within terrestrial arthropod communities, little is known about the biology and ecology of Omus.

Field studies showed that two species of Omus existed in the forested areas of Powell Butte Nature Park, Portland, Oregon, USA: Omus audouiniand O. dejeanii. The co-occurrence of sympatric, and likely syntopic, species allowed for a comparative approach in examining and analyzing …

Candidatus Syngnamydia Venezia, A Novel Member Of The Phylum Chlamydiae From The Broad Nosed Pipefish, Syngnathustyphle Typhle, Alexander Fehr, Elisabeth Walther, Heike Schmidt-Posthaus, Lisbeth Nufer, Anthony B. Wilson, Miroslav Svercel, Denis Richter, Helmut Segner, Andreas Pospischil, Lloyd Vaughan

Publications and Research

Chlamydia are obligate intracellular bacteria and important pathogens of humans and animals. Chlamydia-related bacteria are also major fish pathogens, infecting epithelial cells of the gills and skin to cause the disease epitheliocystis. Given the wide distribution, ancient origins and spectacular diversity of bony fishes, this group offers a rich resource for the identification and isolation of novel Chlamydia. The broad-nosed pipefish (Syngnathus typhle) is a widely distributed and genetically diverse temperate fish species, susceptible to epitheliocystis across much of its range. We describe here a new bacterial species, Candidatus Syngnamydia venezia; epitheliocystis agent of S. typhle and close relative to …

The Misapplication Of Dna Barcodes To Taxonomic Classification, Taylor Southwick, Dr. Keith Crandall

Journal of Undergraduate Research

The classification of organisms into different taxa is a central issue in biology. If similar organisms are grouped together, then comparative analyses can be used from the genome to the systems level to understand how they work, both biologically and behaviorally. There are two ways to perform this classification: morphologically and phylogenetically. Morphological demarcations are based on visual differences in anatomical structure and physiological function. Phylogenetic classification is based upon the evolutionary relationship among the individuals in the population quantified by the similarity or dissimilarity of their DNA strands.

Quantification Of Kaposi’S Sarcoma Herpesvirus Gene Expression In Infected Humanized Mice, Mark Rowan, Dr. Bradford K. Berges

Journal of Undergraduate Research

Kaposi’s Sarcoma Herpesvirus (KSHV) is a prevalent disease around the world. Some Sub- Saharan African countries have infection levels as high as 40 percent. Usually the effects of this disease are not fatal unless the infected person has already been infected with HIV or has some other immunodeficiency. If both of these problems exist, deadly cancers can form within the infected person1. Studies have shown that people with HIV are 200,000 times more likely to have Kaposi’s sarcoma (a cancer caused by KSHV) than those not infected. Until now, no competent animal model existed to study KSHV pathogenesis.

Does Selenium Alter The Expression Of The Large T Antigen In Tramp Mice?, Britlyn Orgill, Dr. Merrill Christensen

Journal of Undergraduate Research

Prostate cancer is the second most common cancer in American men. The American Cancer Society predicts that 217,730 cases of prostate cancer will be diagnosed and that 32,050 men will die from the disease in the year 2010 (1). Since prostate cancer has a long latency period, it is a prime candidate for dietary prevention. Isoflavones, natural compounds found in soy, and selenium, a trace element, have both been previously shown to have protective effects against prostate cancer. The lab of Dr. Merrill Christensen has been studying the effects of these compounds using the Transgenic Adenocarcinoma of the Mouse Prostate …

The Role Of Rage In Inflammatory Lung Disease Induced By Diesel Particulate Matter, Karisa Wasley, Dr. Paul Reynolds

Journal of Undergraduate Research

The causes of high morbidity and mortality associated with inflammatory respiratory diseases are not well understood. My research project helped to shed light on cellular signaling pathways associated with inflammatory disease, particularly those caused by or worsened by air pollutants. Asthmatics, in particular, have a difficult time dealing with common pollutants found in cities, including diesel particulate matter (PM). I focused specifically on the inflammation induced by air pollutants such as diesel PM and the activation of signaling pathways initiated by their binding with the receptors for advanced glycation end-products (RAGE). RAGE is involved developmentally in the lungs and specifically …

Establishing The Spondyloepiphyseal Congenita Heterozygous Mouse As An Animal Model For Human Osteoarthritis, Michael Henderson, Dr. Robert Seegmiller

Journal of Undergraduate Research

Osteoarthritis (OA) causes discomfort and immobility to millions of Americans every year. Due to the high demand for patient pain relief and improved mobility, scientists are seeking to understand the pathway of OA and develop drugs which would illuminate the onset of, and/or the progression of, OA.

The Role Of Htra1, Ddr2, And Mmp-13 Proteins In The Mechanistic Pathway Leading To Osteoarthritis In Sedc Mice, David Holt, Robert Seegmiller

Journal of Undergraduate Research

In the present study, we report OA in a mouse model that, like the human families presented by Kannu et al., bears a heterozygous mutation in the Col2a1 gene but has a phenotypically normal skeleton.1 The mouse mutation was named sedc by Donahue et al. because when homozygous, it produces feature that resemble the most common clinical phenotypes of SED congenita in humans, including abnormal epiphyses, flattened vertebral bodies, and problems with the eyes and ears.2 The mutation consists of a single base pair substitution in exon 48 of the Col2a1 gene, which changes an arginine to a cysteine in …

Transcriptome Deep-Sequencing And Clustering Of Expressed Isoforms From Favia Corals, Shaadi F. Pooyaei Mehr, Rob Desalle, Hung-Teh Kao, Apurva Narechania, Zhou Han, Dan Tchernov, Vincent A. Pieribone, David F. Gruber

Publications and Research

Background: Genomic and transcriptomic sequence data are essential tools for tackling ecological problems. Using an approach that combines next-generation sequencing, de novo transcriptome assembly, gene annotation and synthetic gene construction, we identify and cluster the protein families from Favia corals from the northern Red Sea.

Results: We obtained 80 million 75 bp paired-end cDNA reads from two Favia adult samples collected at 65 m (Fav1, Fav2) on the Illumina GA platform, and generated two de novo assemblies using ABySS and CAP3. After removing redundancy and filtering out low quality reads, our transcriptome datasets contained 58,268 (Fav1) and 62,469 (Fav2) contigs …

Fast Segmentation And High-Quality Three-Dimensional Volume Mesh Creation From Medical Images For Diffuse Optical Tomography, Michael Jermyn, Hamid Ghadyani, Michael A. Mastanduno, Wes Turner, Scott C. Davis, Hamid Dehghani, Brian W. Pogue

Dartmouth Scholarship

Multimodal approaches that combine near-infrared (NIR) and conventional imaging modalities have been shown to improve optical parameter estimation dramatically and thus represent a prevailing trend in NIR imaging. These approaches typically involve applying anatomical templates from magnetic resonance imaging/computed tomography/ultrasound images to guide the recovery of optical parameters. However, merging these data sets using current technology requires multiple software packages, substantial expertise, significant time-commitment, and often results in unacceptably poor mesh quality for optical image reconstruction, a reality that represents a significant roadblock for translational research of multimodal NIR imaging. This work addresses these challenges directly by introducing automated digital …

An Excerpt From Al-Sayyid Asghar Akbar By Murtedha Gzar, Yasmeen S. Hanoosh

World Languages and Literatures Faculty Publications and Presentations

The following is a translation of an excerpt from the novel Al-Sayyid Asghar Ak bar (Dar al-Tanwir, 2012) by Iraqi author Murtedha Gzar. This recent work by a young engineer from the southern city of Basra has received considerable attention in literary circles at home and abroad, significantly for the ways in which it departs from the mimetic norms of social realism that were found in the established narratological models of the pre-2003 U.S. occupation era, such as the varieties cultivated in the 1960s and 1970s in Iraq by seminal authors lik e Gha’ib Ṭu`mah Farman, Mahdi Isa al-Saqr, and …

The Genus Odontophrynus (Anura: Odontophrynidae): A Larval Perspective, Filipe Augusto C. Do Nascimento, Tamí Mott, José A. Langone, Christine A. Davis, Rafael O. De Sá

Biology Faculty Publications

The genus Odontophrynus consists of 11 species of medium-sized frogs distributed across south and east South America. This study examines and describes the chondrocrania and oral cavities of 0. americanus, 0. maisuma, 0. carvalhoi, and 0. cu/tripes, and reviews current knowledge about the larval external morphology of the genus. Twenty-one tadpoles were cleared and double-stained for chondrocranium description and five tadpoles were dissected for analysis in a scanning electron microscope. The presence of a tectum parientale may be considered here as a putative synapomorphy of the genus. The 0. americanus and 0. cu/tripes species groups were partially differentiated by the …