Digital Commons Network^™

A Study Of Adiponectin In Children With Diabetes Mellitus, Basma A. Ali, Doaa M. Mahrous, Ahlam M. Fikri, Mina

Sultan Qaboos University Medical Journal

Objectives: Adiponectin is a hormone produced by adipose tissue. It is secreted exclusively by adipocytes and appears to play a role in the pathophysiology of obesity, diabetes mellitus (DM), and its comorbidities. The aim of this study was to assess adiponectin levels in diabetic children with type 1 DM (T1DM) and type 2 DM (T2DM), and to detect its prognostic role in them. Methods: This study was undertaken from April to July 2011 at Minia University Children’s Hospital, Egypt, and included 314 children aged 2–18 years divided into two patient groups. Group I consisted of 164 pre-diagnosed diabetic patients, further …

Implications Of A Chr7q21.11 Microdeletion And The Role Of The Pclo Gene In Developmental Delay, Roberto L. Mazzaschi, Fern Ashton, Salim George, Alice M., Donald R. Love

Sultan Qaboos University Medical Journal

We report here a 4-year-old boy with global developmental delay who was referred for karyotyping and fragile X studies. A small interstitial deletion on chromosome 7 at band 7q21 was detected in all cells examined. Subsequent molecular karyotype analysis gave the more detailed result of a 6.3 Mb heterozygous deletion involving the interstitial chromosome region 7q21.11. In this relatively gene-poor region, the presynaptic cytomatrix protein, Piccolo (PCLO) gene appears to be the most likely candidate for copy number loss leading to a clinical phenotype. G-banded chromosome analysis of the parents showed this deletion was inherited from the father. Molecular karyotype …

The Foreign Ear: Elizabeth Bishop's Proliferal Wit & The Chances Of Change, Kelly Barrett Brown

All Theses and Dissertations (ETDs)

Abstract

The Foreign Ear: Elizabeth Bishop's Proliferal Wit & the Chances of Change

Elizabeth Bishop has been widely celebrated as a painterly or photographic poet, a naturalist and geographer, and yet she was a subtly exquisite musician of wordplay attuned to subvocal effects. This dissertation examines a network of Bishop's affinities and aesthetic commitments, including her wish to "say the most difficult things" and "be funny, if possible." One surprising claim regarding the poet's variously called "All Eye," "the famous eye," etc., is that her sense of the spiritual is rather antithetical to an ocular regime: even those extremely fluid, …

Patterning In Placental 11-B Hydroxysteroid Dehydrogenase Methylation According To Prenatal Socioeconomic Adversity, Allison A. Appleton, David A. Armstrong, Corina Lesseur, Joyce Lee, James F. Padbury, Barry M. Lester

Dartmouth Scholarship

Background:

Prenatal socioeconomic adversity as an intrauterine exposure is associated with a range of perinatal outcomes although the explanatory mechanisms are not well understood. The development of the fetus can be shaped by the intrauterine environment through alterations in the function of the placenta. In the placenta, the HSD11B2 gene encodes the 11-beta hydroxysteroid dehydrogenase enzyme, which is responsible for the inactivation of maternal cortisol thereby protecting the developing fetus from this exposure. This gene is regulated by DNA methylation, and this methylation and the expression it controls has been shown to be susceptible to a variety of stressors from …

Above-Ground Biomass And Structure Of 260 African Tropical Forests, Simon L. Lewis, Bonaventure Sonké, Terry Sunderland, Serge K. Begne, Gabriela Lopez-Gonzalez, Der Heijden Gmf Van, Oliver L. Phillips, Kofi Affum-Baffoe, Timothy R. Baker, Lindsay Banin, Jean François Bastin, Hans Beeckman, Pascal Boeckx, Jan Bogaert, Cannière C De, Eric Chezeaux, Connie J. Clark, Murray Collins, Gloria Djagbletey, Marie Noël K. Djuikouo, Vincent Droissart, Jean Louis Doucet, Cornielle E.N. Ewango, Sophie Fauset, Ted R. Feldpausch, Ernest G. Foli, Jean François Gillet, Alan C. Hamilton, David J. Harris, Terese B. Hart, Haulleville T De, Annette Hladik, Koen Hufkens, Dries Huygens, Philippe Jeanmart, Kathryn J. Jeffery, Elizabeth Kearsley, Miguel E. Leal, Jon Lloyd, Jon C. Lovett, Jean Remy Makana, Yadvinder Malhi, Andrew R. Marshall, Lucas Ojo, Kelvin S.H. Peh, Georgia Pickavance, John R. Poulsen, Jan M. Reitsma, Douglas Sheil, Murielle Simo, Kathy Steppe, Hermann E. Taedoumg, Joey Talbot, James R.D. Taplin, David Taylor, Sean C. Thomas, Benjamin Toirambe, Hans Verbeeck, Jason Vleminckx, Lee J.T. White, Simon Willcock, Hannsjorg Woell, Lise Zemagho

School of Geography, Earth and Environmental Sciences

We report above-ground biomass (AGB), basal area, stem density and wood mass density estimates from 260 sample plots (mean size: 1.2 ha) in intact closed-canopy tropical forests across 12 African countries. Mean AGB is 395.7 Mg dry mass ha −1 (95% CI: 14.3), substantially higher than Amazonian values, with the Congo Basin and contiguous forest region attaining AGB values (429 Mg ha −1 ) similar to those of Bornean forests, and significantly greater than East or West African forests. AGB therefore appears generally higher in palaeo- compared with neotropical forests. However, mean stem density is low (426 ± 11 stems …

The Daily Egyptian, September 04, 2013, Daily Egyptian Staff

September 2013

No abstract provided.

Volume 105 Issue 1, Southwestern Oklahoma State University

The Southwestern - Archive

No abstract provided.

Prospectus, September 4, 2013, Ted Sutterlund, Matthew Jackson, Alex Wallner, Mace Mackiewicz

Prospectus 2013

CARPOOL PARKING: EASY ALTERNATIVE FOR DRIVERS?; The right reasons to pick a college; 200 years very Grimm trivia; CAS a good resource for students; Before the missiles fly against Syria; Down with the patent trolls; Cobra volleyball continues hot start; Parkland Art Gallery features new fall exhibits

The Murray Ledger And Times, September 4, 2013, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Skin Lesions In European Hibernating Bats Associated With Geomyces Destructans, The Etiologic Agent Of White-Nose Syndrome, Gudrun Wibbelt, Sébastien J. Puechmaille, Bernd Ohlendorf, Kristin Mühldorfer, Thijs Bosch, Tamás Görföl, Karsten Passior, Andreas Kurth, Daniel Lacremans, Frédéric Forget

KIP Articles

No abstract provided.

The Winonan, Winona State University

The Winonan - 2010s

No abstract provided.

Independent - Sep. 4, 2013, Jacklyn Nowotnik

The Independent (1988-present)

No abstract provided.

Human-Swarm Interaction: Effects On Operator Workload, Scale, And Swarm Topology, Brian O. Pendleton

Theses and Dissertations

Robots, including UAVs, have found increasing use in helping humans with dangerous and difficult tasks. The number of robots in use is increasing and is likely to continue increasing in the future. As the number of robots increases, human operators will need to coordinate and control the actions of large teams of robots. While multi-robot supervisory control has been widely studied, it requires that an operator divide his or her attention between robots. Consequently, the use of multi-robot supervisory control is limited by the number of robots that a human or team of humans can reasonably control. Swarm robotics -- …

Ancient Lineage, Young Troglobites: Recent Colonization Of Caves By Nesticella Spiders, Yuanyuan Zhang, Shuqiang Li

KIP Articles

Background: The evolution and origin of cave organisms is a recurring issue in evolutionary studies, but analyses are often hindered by the inaccessibility of caves, morphological convergence, and complex colonization processes. Here we investigated the evolutionary history of Nesticella cave spiders, which are mainly distributed in the Yunnan–Guizhou Plateau, China. With comprehensive sampling and phylogenetic and coalescent-based analyses, we investigated the tempo and mode of diversification and the origins of these troglobites. We also aimed to determine which factors have influenced the diversification of this little-known group. Results: Coalescent-based species delimitation validated the 18 species recognized by morphological inspection and …

Gm Minutes 9/4/2013, Brandon Telchi

Judicial Branch Publications

No abstract provided.

Volume 51, Number 3: September 04, 2013, University Of North Dakota

University Letter Archive

No abstract provided.

The Parthenon, September 4, 2013, Bishop Nash

The Parthenon

The Parthenon, Marshall University’s student newspaper, is published by students Monday through Friday during the regular semester and weekly Thursday during the summer. The editorial staff is responsible for the news and the editorial content.

A Selection Of Biomechanical Research Problems : From Modeling To Experimentation, Cyrus Abbasi

Mechanical Engineering ETDs

The research undertakings within this manuscript illustrate the importance of biomechanics in todays science. Without doubt, biomechanics can be utilized to obtain a better understanding of many unsolved mysteries involved in the field of medicine. Moreover, biomechanics can be used to develop better prosthetic or surgical devices as well. Chapter 2 represents a medical problem, which has not been solved for more than a century. With the use of fundamental principles of biomechanics, a better insight of this problem and its possible causes were obtained. Chapter 3 investigates the mechanical interaction between the human teeth and some processed food products …

The Daily Gamecock, Wednesday, September 4, 2013, University Of South Carolina, Office Of Student Media

August

No abstract provided.

Pseudomonas Aeruginosa Exotoxin Y-Mediated Tau Hyperphosphorylation Impairs Microtubule Assembly In Pulmonary Microvascular Endothelial Cells, Ron Balczon, Nutan Prasain, Cristhiaan Ochoa, Jason Prater, Bing Zhu, Mikhail Alexeyev, Sarah Sayner, Dara W. Frank, Troy Stevens

University Faculty and Staff Publications

Pseudomonas aeruginosa uses a type III secretion system to introduce the adenylyl and guanylyl cyclase exotoxin Y (ExoY) into the cytoplasm of endothelial cells. ExoY induces Tau hyperphosphorylation and insolubility, microtubule breakdown, barrier disruption and edema, although the mechanism(s) responsible for microtubule breakdown remain poorly understood. Here we investigated both microtubule behavior and centrosome activity to test the hypothesis that ExoY disrupts microtubule dynamics. Fluorescence microscopy determined that infected pulmonary microvascular endothelial cells contained fewer microtubules than control cells, and further studies demonstrated that the microtubule-associated protein Tau was hyperphosphorylated following infection and dissociated from microtubules. Disassembly/reassembly studies determined that …

Metagenomic Profiling Reveals Lignocellulose Degrading System In A Microbial Community Associated With A Wood-Feeding Beetle, Erin D. Scully, Scott M. Geib, Kelli Hoover, Ming Tien, Susannah G. Tringe, Kerrie W. Barry, Tijana Glavina Del Rio, Mansi Chovatia, Joshua R. Herr, John E. Carlson

Department of Plant Pathology: Faculty Publications

The Asian longhorned beetle (Anoplophora glabripennis) is an invasive, wood-boring pest that thrives in the heartwood of deciduous tree species. A large impediment faced by A. glabripennis as it feeds on woody tissue is lignin, a highly recalcitrant biopolymer that reduces access to sugars and other nutrients locked in cellulose and hemicellulose. We previously demonstrated that lignin, cellulose, and hemicellulose are actively deconstructed in the beetle gut and that the gut harbors an assemblage of microbes hypothesized to make significant contributions to these processes. While lignin degrading mechanisms have been well characterized in pure cultures of white rot basidiomycetes, little …

A Mechanochemical Study Into The Growth And Shape Maintenance Of Rod-Shaped Bacteria, Akeisha Belgrave

Doctoral Dissertations

Rod-shaped bacteria grow in length without changing their width [1, 2]. A major feature of bacterial cell growth is the remodeling of the cell wall, the primary structure giving the bacterium its shape and structural integrity. In many rod-shaped bacteria, the process by which the cell wall gets larger as the cell grows involves severing bonds that link the existing cell wall material together in order to insert and bind new material. Coordination between severing and insertion is likely necessary in order to prevent the cell wall from rupturing due to the large pressure difference between the inside and outside …

Designing The Wheel: Built-In Instructional Technology, Pat Reid, Donalee Attardo

IMPACT Publications

Like many higher education institutions, Purdue University struggles to provide faculty with the support they need to incorporate sound use of instructional technologies in their courses. Two years ago Provost Tim Sands made a commitment to both instructional technologies and active learning, which included $100,000 funding for Instruction Matters: Purdue Academic Course Transformation (IMPACT). Goals of the IMPACT project include:

• Develop a network of faculty knowledgeable in teaching and learning best practices and passionate about teaching through faculty learning communities
• Base course redesign on best practices and sound research
• Support faculty-led course redesign with campus-wide resources

IMPACT funding has …

The Power Of The Claw, Bruce M. Rothschild, Bill Bryant, Christopher Hubbard, Kent Tuxhorn, Ginny Penn Kilgore, Larry Martin, Virginia L. Naples

Faculty Articles, Papers, and Other Scholarship

Scratches on bones have routinely been attributed to tooth marks (a predominantly untested speculation), ignoring the effects of claws, perhaps because of the general assumption that claws are too soft to damage bone. However, some pathologies appears to be more compatible with claw rather than tooth impacts. Therefore, it is critical to determine if the claws of any animal are capable of scratching into the surface of any bone – a test and proof of concept. A tiger enrichment program was used to document actual bone damage unequivocally caused by claws, by assuring that the tiger had access to bones …

Juvenile King Scallop, Pecten Maximus, Is Potentially Tolerant To Low Levels Of Ocean Acidification When Food Is Unrestricted, Mb Sanders, Tp Bean, Th Hutchinson, Quesne Wjf Le

School of Geography, Earth and Environmental Sciences

No abstract provided.

Predicting Free-Space Occupancy On Novel Artificial Structures By An Invasive Intertidal Barnacle Using A Removal Experiment, Sa Bracewell, La Robinson, Lb Firth, Am Knights

School of Biological and Marine Sciences

Artificial structures can create novel habitat in the marine environment that has been associated with the spread of invasive species. They are often located in areas of high disturbance and can vary significantly in the area of free space provided for settlement of marine organisms. Whilst correlation between the amount of free space available and recruitment success has been shown in populations of several marine benthic organisms, there has been relatively little focus on invasive species, a group with the potential to reproduce in vast numbers and colonise habitats rapidly. Invasion success following different scales of disturbance was examined in …

Spatially Explicit Data: Stewardship And Ethical Challenges In Science, Joel N. Hartter, Sadie J. Ryan, Catrina A. Mackenzie, John N. Parker, Carly A. Strasser

Geography

Scholarly communication is at an unprecedented turning point created in part by the increasing saliency of data stewardship and data sharing. Formal data management plans represent a new emphasis in research, enabling access to data at higher volumes and more quickly, and the potential for replication and augmentation of existing research. Data sharing has recently transformed the practice, scope, content, and applicability of research in several disciplines, in particular in relation to spatially specific data. This lends exciting potentiality, but the most effective ways in which to implement such changes, particularly for disciplines involving human subjects and other sensitive information, …

Incorporating Household Pets And Service Animals: Local Government Emergency Preparedness In New Mexico, Jesse Austin Sievers

Public Administration ETDs

Public Law 109-308, the Pet Evacuation and Transportation Standards Act of 2006 (PETS Act), requires states and local governments seeking federal assistance to have emergency preparedness operational plans address the needs of individuals with household pets and service animals prior to a disaster. This thesis examines how local government emergency managers in New Mexico are preparing to address the needs of individuals with household pets and service animals prior to a disaster. This research was an exploratory case study that addressed two study goals: 1) to develop a baseline to measure preparedness activity surrounding the PETS Act implementation in New …

A Novel Mglur5 Antagonist, Mfz 10-7, Inhibits Cocaine-Taking And Cocaine-Seeking Behavior In Rats, Thomas Keck, Mu-Fa Zou, Gui-Hua Bi, Hai-Ying Zhang, Xiao-Fei Wang, Hong-Ju Yang, Ratika Srivastava, Elliott L. Gardner, Zheng-Xiong Xi, Amy Hauck Newman

College of Science & Mathematics Departmental Research

Pre-clinical studies suggest that negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 5 (mGluR5), including 2-methyl-6-(phenylethynyl)pyridine (MPEP), 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine (MTEP) and fenobam are highly effective in attenuating drug-taking and drug-seeking behaviors. However, both MPEP and MTEP have no translational potential for use in humans because of their off-target effects and short half-lives. Here, we report that 3-fluoro-5-[(6-methylpyridin-2-yl)ethynyl]benzonitrile (MFZ 10-7), a novel mGluR5 NAM, is more potent and selective than MPEP, MTEP and fenobam in both in vitro binding and functional assays. Similar to MTEP, intraperitoneal administration of MFZ 10-7 inhibited intravenous cocaine self-administration, cocaine-induced reinstatement of drug-seeking behavior and …

Current, September 03, 2013, University Of Missouri-St. Louis

Current (2010s)

No abstract provided.