Digital Commons Network^™

Justice William J. Brennan, Jr., James Wilson, And The Pursuit Of Equality And Liberty, Deborah A. Roy

Cleveland State Law Review

This Article analyzes the jurisprudence of one of the most transformative Supreme Court Justices, William J. Brennan, Jr., from the perspective of his vision that the United States Constitution is founded on Human Dignity. Justice Brennan expressed this principle in his opinions that advanced the realization of individual rights for each and every American. The principle of human dignity invokes the values of equality and liberty. The article shows that Justice Brennan traced the principle of human dignity back to the Founding Fathers and the constitutional government that they established. Rather than being unhinged from the Constitution as his critics …

Table Of Contents, Cleveland State Law Review

Cleveland State Law Review

No abstract provided.

Calypso: Effecting Conflict Transformation Through The Indigenous Calypso Art-Form, Edward M. Phillips

Journal of Global Initiatives: Policy, Pedagogy, Perspective

The calypso, which forms an integral part of the carnival celebrations of the Republic of Trinidad and Tobago, is a syncretic popular art-form that has its origin in Africa. The art-form, having been influenced and adapted by the experiences of enslaved Africans in the Diaspora, has been fused in the vortex of plantation society. Today, the music of carnival has evolved considerably, with the calypso becoming one of the cornerstones of the carnival celebration. This paper looks at aspects of the subset of political calypsos that offer commentary on the socio-political and/or economic issues in the Republic of Trinidad and …

Introduction: The Year Of Ghana At Kennesaw State University, Dan Paracka, Sam Abaidoo

Journal of Global Initiatives: Policy, Pedagogy, Perspective

Introduction to the issue.

Simulating Land Use Land Cover Change Using Data Mining And Machine Learning Algorithms, Amin Tayyebi

Open Access Dissertations

The objectives of this dissertation are to: (1) review the breadth and depth of land use land cover (LUCC) issues that are being addressed by the land change science community by discussing how an existing model, Purdue's Land Transformation Model (LTM), has been used to better understand these very important issues; (2) summarize the current state-of-the-art in LUCC modeling in an attempt to provide a context for the advances in LUCC modeling presented here; (3) use a variety of statistical, data mining and machine learning algorithms to model single LUCC transitions in diverse regions of the world (e.g. United States …

Fate Of 17Α-Estradiol, 17Β-Estradiol, And Estrone In Agricultural Soils And Sediments, Michael L. Mashtare Jr

Open Access Dissertations

The shift to concentrated animal production facilities and increasing rural-urban migration has increased the localized land application of nearly 1 billion tons of manure and biosolids annually. Although these applications provide nutrients and contribute to soil tilth, they also serve as a source for an estimated 49 tons of the natural manure-borne estrogens, 17α-estradiol (17α-E2), 17β-estradiol (17β-E2), and estrone (E1). While these estrogens are critical to endocrine systems, the low concentrations observed in the environment can disrupt endocrine function in non-target organisms, e.g., altering secondary sex characteristics which can lead to changes in wildlife communities.

Research presented here focuses on …

Understanding Osmoregulation And Immunity In Heteromyid Rodents Through Insights Gained From Rna-Seq, Nicholas John Marra

Open Access Dissertations

Understanding the genetic basis of adaptation is one of the central questions of evolutionary genetics. In the face of selective pressure, individuals with adaptive phenotypes survive and pass on their beneficial alleles that conferred this fitness advantage. Over sufficient time scales and under strong selection, differences accumulate between taxa in the form of physical and/or behavioral traits that have been shaped differently. By looking at the transcriptomes of related taxa we can identify sequence and regulatory differences that represent molecular signatures of these different selection regimes. When we study these differences between taxa that have evolved under opposing selective forces …

Neuroprotection By Chitosan And Chitosan Nanoparticles, Bojun Chen

Open Access Dissertations

In the U.S., about 200,000 people are currently living with spinal cord injury (SCI). An estimated of 50%-70% of all SCI cases occurs in the range of ages between 15-35 years old. The destructive neurotrauma results in the majority of adult disability, even after patients suffering with SCI survived from the acute death. There are two stages involved in the progression of SCI, the primary stage and the secondary stage. The primary stage is mainly the mechanical damage to the central nervous system. The rapid collapse of the integrity of cell membrane and tissue is often one of the initial …

The Journal Of Social Theory In Art Education

Journal of Social Theory in Art Education

No abstract provided.

Craft As Activism, Elizabeth Garber

Journal of Social Theory in Art Education

Craft activists work outside the mainstream of consumer society, in grass-roots efforts, to create social change that positions individuals and groups of people as reflective contributors who occupy a participatory democracy. These activities connect to and draw from feminist and other civil rights movements, sustainability, and do-it-yourself [DIY] activities. They are forms of affective labor. The crafted products are considered in terms of whether they contribute (or do not) to the surplus economy, in terms of class taste, and vis-à-vis their ability to connect people and contribute to social change. Education of craft activists and audiences takes informal forms, such …

Cardioprotective Effects Of Mitochondrial-Targeted Antioxidants In Myocardial Ischemia/Reperfusion (I/R) Injury, Regina Ondrasik

PCOM Biomedical Studies Student Scholarship

Reactive oxygen species (ROS) generated during myocardial I/R contribute to post-reperfused cardiac contractile dysfunction. Damaged cardiomyocyte mitochondria are major sites of excess ROS generation during reperfusion. We hypothesized that reducing mitochondrial ROS formation should attenuate myocardial I/R injury and thereby improve function of isolated perfused rat hearts subjected to I(30min)/R(45min) compared to untreated I/R hearts. Mitoquinone (MitoQ, MW=579g/mol; complexed with cyclodextrin (MW=1135g/mol) to improve water solubility, total MW=1714g/mol), a coenzyme Q derivative, and SS-31 (Szeto-Schiller) peptide ((D-Arg)-Dmt-Lys-Phe-Amide, MW=639g/mol, Genemed Synthesis, Inc., San Antonio, TX), an alternating cationic-aromatic peptide, are selective mitochondrial ROS inhibitors which significantly improved post-reperfused cardiac function compared …

Effect Of Ergot Alkaloids On Bovine Foregut Vasculature, Nutrient Absorption, And Epithelial Barrier Function, Andrew P. Foote

Theses and Dissertations--Animal and Food Sciences

Ergot alkaloids present in endophyte-infected (E+) tall fescue are thought to be the causative agent of fescue toxicosis, a syndrome affecting cattle in the eastern United States. Many of the observed signs of fescue toxicosis are thought to be attributed to peripheral vasoconstriction; however, there are data indicating that ergot alkaloids can alter blood flow to the gut. An experiment was conducted using right ruminal artery and vein collected from heifers shortly after slaughter. Vessels were mounted in a multi-myograph to determine the vasoconstrictive potentials of ergot alkaloids present in E+ tall fescue. Results indicated ergot alkaloids have the potential …

Evaluating Food Safety Systems Development And Implementation By Quantifying Haccp Training Durability, Marienne A. Anandappa

Theses and Dissertations--Animal and Food Sciences

HACCP-based food safety programs have been widely acclaimed, accepted and implemented as an effective means of managing food safety risks. While HACCP training is a cornerstone of managing HACCP programs, there is little information about the effectiveness of HACCP training and the durability of HACCP knowledge. Findings reveal a link between involvement level in HACCP activities and the accuracy of HACCP knowledge over time. Opportunities for peer training in HACCP, irrespective of overall experience in the food industry provide favorable circumstances for maintaining accuracy of HACCP knowledge. The optimal window for engaging employees in HACCP is directly following the completion …

Estimating The Economic Losses From Diseases And Extended Days Open With A Farm-Level Stochastic Model, Di Liang

Theses and Dissertations--Animal and Food Sciences

This thesis improved a farm-level stochastic model with Monte Carlo simulation to estimate the impact of health performance and market conditions on dairy farm economics. The main objective of this model was to estimate the costs of seven common clinical dairy diseases (mastitis, lameness, metritis, retained placenta, left displaced abomasum, ketosis, and milk fever) in the U.S. An online survey was conducted to estimate veterinary fees, treatment costs, and producer labor data. The total disease costs were higher in multiparous cows than in primiparous cows. Left displaced abomasum had the greatest costs in all parities ($404.74 in primiparous cows and …

Effects Of Endophyte Infected Fescue Alkaloid Ingestion On Energy Metabolism, Nitrogen Balance, In Situ Feed Degradation, And Ruminal Passage Rates, Anne F. Koontz

Theses and Dissertations--Animal and Food Sciences

The decrease in productivity caused by fescue toxicosis has been estimated to cost the United States livestock industry more than $1 billion per year due to reduced growth and diminished reproductive efficiency. This goal of the research presented in this dissertation is to enhance the knowledge base concerning the underlying physiological changes that occur during fescue toxicosis that lead to reduced intake and weight gain in cattle.

As one of the factors associated with fescue toxicosis is a reduction in feed intake, achieving a consistent and adequate intake of toxins can be a complication. Results from experiment 1demonstrate that ruminal …

Evaluation Of The Effects Of Vitamin K On Growth Performance And Bone Health In Swine, James S. Monegue

Theses and Dissertations--Animal and Food Sciences

The role of vitamin K in the blood clotting cascade has been well documented. Vitamin K has recently been implicated in improving bone health. The current studies were conducted to determine the effects of vitamin K in diets with and without mycotoxin contaminated corn on growth performance, bone characteristics, and related blood metabolites in pigs from weaning to market. Menadione sodium bisulfite complex (MSBC, 33% vitamin K) was chosen as the source of supplemental vitamin K because it is the most common form fed to swine. Vitamin K was tested at 0, 0.5, and 2.0 ppm in a corn-soybean meal …

Paper Moon, Teresa Bramlette Reeves, Kirstie Tepper, Jessica Stephenson

Exhibition Publications

Paper Moon focused on work that, in one way or another, served as a substitute for the real thing. The emphasis of this exchange was not on artifice but rather on a sincere effort to imitate an ideal, the desire for which may be motivated by limited circumstances, need, adoration, and longing, rather than greed or irony. The show examined how these substitutes were intended to function, the nature of their appeal, and what role authenticity and our ability to “make believe” played in the proffered illusion.

The idea for this exhibition began with a documentary about teenage magicians and …

Brady, Arkansas Rule 17.1, And Disclosure Of Scientific Evidence And Expert Opinion, J. Thomas Sullivan

University of Arkansas at Little Rock Law Review

The United States Constitution as well as state procedural rules require prosecutorial authorities to disclose evidence to the defense as a means for ensuring fairness in the prosecution of individuals charged with criminal offenses. When prosecutorial authorities fail to disclose evidence as required, the integrity of the criminal justice system is threatened and the defense is unable to adequately prepare for trial. This threat is illustrated and magnified by the substantiation of prosecutorial misconduct claims in high profile trials where prosecutors have been unable to resist the temptation not to disclose evidence that could damage the prosecution's case, or, where …

The Rise And Demise Of The Absolute Dominion Doctrine For Groundwater, Joseph W. Dellapenna

University of Arkansas at Little Rock Law Review

Increased human populations, together with increased per capita water usage and climate changes, have resulted in our planet coping with greater water shortages than ever before. Groundwater has played, and will continue to play, a critical role in dealing with water shortages. Consequently, more and more attention, legal and otherwise, is being given to groundwater across the United States.

Much legal confusion about groundwater exists. For starters, there is no single legal definition for groundwater. Moreover, the law has developed legal categories such as percolating water and underground streams which, while contradictory to scientific hydrology, remain embedded in the law. …

Western Universalism And African Homosexualties, Nicholas Kahn-Fogel

Law Faculty Scholarship

This article draws on original historical research, queer theory, communitarian philosophy, and an array of anthropological sources to suggest that efforts by Western liberals to protect practitioners of same-sex intimate conduct in Africa may be relatively unsuccessful and could further endanger the intended beneficiaries of advocacy.

Brady, Arkansas Rule 17.1, And Disclosure Of Scientific Evidence And Expert Opinion, J. Thomas Sullivan

Law Faculty Scholarship

No abstract provided.

It’S (Not) Just A Figure Of Speech: Rescuing Metaphor, Anna O. Soter

The Journal of the Assembly for Expanded Perspectives on Learning

Look for ways that students can study metaphor in everyday language, rather than confine its study to poetry.

Number 54 (January 2013)

Southeastern Fishes Council Proceedings

Reproductive Biology of the Frecklebelly Darter, Percina stictogaster (Teleostei: Percidae) by David J. Eisenhour, Audrey M. Richter, Lynn V. Eisenhour, and Carol-Rose Gingra

Post-Hurricane Katrina Survey for the Blackmouth Shiner (Notropis melanostomus) at Historical Localities in Mississippi by Martin T. O’Connell and Ann M. Usee O’Connell

Rediscovery of a lost Paratype of the Boulder Darter, Etheostoma wapiti by Michael H. Doosey

Minutes, Business Meeting, 37th Annual Meeting, Southeastern Fishes Council

2011 Treasurer's Report for the Southeastern Fishes Council

Rediscovery Of A Lost Paratype Of The Boulder Darter, Etheostoma Wapiti, Michael H. Doosey

Southeastern Fishes Council Proceedings

No abstract provided.

Molecular Staging Of Node Negative Patients With Colorectal Cancer., Terry Hyslop, Scott A Waldman

Department of Pharmacology and Experimental Therapeutics Faculty Papers

Metastatic disease is the principle cause of death from colorectal cancer. In that context, the most significant indicator of overall survival and therapeutic response to adjuvant chemotherapy is the presence of metastatic tumor cells in regional lymph nodes. Although histopathologic analysis of lymph nodes is central to all colorectal cancer staging paradigms, its prognostic and predictive value is limited. Indeed, about 30% of patients with histopathology-negative lymph nodes (pN0) die from metastatic disease, reflected by microscopic lymph node metastases that are overlooked by standard techniques. These unrecognized tumor cells are especially important when considering racial disparities in outcomes in colorectal …

Loss Of Mef2d Expression Inhibits Differentiation And Contributes To Oncogenesis In Rhabdomyosarcoma Cells., Meiling Zhang, Jamie Truscott, Judith Davie

Articles

BACKGROUND: Rhabdomyosarcoma (RMS) is a highly malignant pediatric cancer that is the most common form of soft tissue tumors in children. RMS cells have many features of skeletal muscle cells, yet do not differentiate. Thus, our studies have focused on the defects present in these cells that block myogenesis.

METHODS: Protein and RNA analysis identified the loss of MEF2D in RMS cells. MEF2D was expressed in RD and RH30 cells by transient transfection and selection of stable cell lines, respectively, to demonstrate the rescue of muscle differentiation observed. A combination of techniques such as proliferation assays, scratch assays and soft …

Exploring Linkages Between Consumer Food Co-Operatives And Domestic Fair Trade In The United States, Leslie Duram

Publications

Consumer Food Co-operatives (co-ops) have provided consumers an alternative to corporate supermarkets and big-box stores since the 1960s. Producers seeking broader marketing opportunities often turn to co-ops. This study examines how, within Alternative Food Networks (AFNs), co-ops play a role in the emergence of the Domestic Fair Trade movement in the US. The Domestic Fair Trade (DFT) movement is based on the idea that family farms and small- to mid-sized farms in the global north are facing many of the same pressures as producers in the global south. The Domestic Fair Trade Association (DFTA) in the United States is the …

Additional Quantitative Trait Loci And Candidate Genes For Seed Isoflavone Content In Soybean, M Akond, Bazelle Richard, Bobby Ragin, Harmin Herrera, Umerah Kaodi, Cevdet Akbay, Stella K. Kantartzi, Victor Njiti, Abdelali Barakat, Khalid Meksem, David A. Lightfoot, My Abdelmajid Kassem

Articles

Seed isoflavone content of soybean (Glycine max L. Merr.) is a trait of moderate heritablity and an ideal target for marker selection. To date over 20 QTL have been identified underlying this trait among seven populations. The objectives of this study were to identify additional QTL and candidate genes controlling isoflavone content in a set of recombinant inbred line (RIL) populations of soybean grown in two different seasons. Variations of isoflavones namely daidzein, glycitein and genistein contents over two growing seasons and locations suggests that isoflavones are influenced by both genes and environments. Six QTL were identified on five …

Intrinsic Disorder In Pten And Its Interactome Confers Structural Plasticity And Functional Versatility, Prerna Malaney, Ravi Ramesh Pathak, Bin Xue, Vladimir N. Uversky, Vrushank Davé

Molecular Medicine Faculty Publications

IDPs, while structurally poor, are functionally rich by virtue of their flexibility and modularity. However, how mutations in IDPs elicit diseases, remain elusive. Herein, we have identified tumor suppressor PTEN as an intrinsically disordered protein (IDP) and elucidated the molecular principles by which its intrinsically disordered region (IDR) at the carboxyl-terminus (C-tail) executes its functions. Post-translational modifications, conserved eukaryotic linear motifs and molecular recognition features present in the C-tail IDR enhance PTEN's protein-protein interactions that are required for its myriad cellular functions. PTEN primary and secondary interactomes are also enriched in IDPs, most being cancer related, revealing that PTEN functions …

Alpha 1-Antichymotrypsin, An Inflammatory Protein Overexpressed In The Brains Of Patients With Alzheimer’S Disease, Induces Tau Hyperphosphorylation Through C-Jun N-Terminal Kinase Activation, Ethika Tyagi, Tina Fiorelli, Michelle Norden, Jaya Padmanabhan

Molecular Medicine Faculty Publications

The association of inflammatory proteins with neuritic plaques in the brains of Alzheimer’s disease (AD) patients has led to the hypothesis that inflammation plays a pivotal role in the development of pathology in AD. Earlier studies have shown that alpha 1-antichymotrypsin (ACT) enhances amyloid beta fibrillization and accelerated plaque formation in APP transgenic mice. Later studies from our laboratory have shown that purified ACT induces tau hyperphosphorylation and degeneration in neurons. In order to understand the mechanisms by which inflammatory proteins enhance tau hyperphosphorylation, we injected interleukin-1β (IL-1β) intracerebroventricularly into mice expressing human ACT, human tau, or …