Digital Commons Network^™

The Effects Of Concentration, Stir Rate, And Processing Temperature On The Iridescence Of Polymethyl Methacrylate Nanoparticles, David Baruela

Materials Engineering

Synthetic opals were synthesized by creating polymethyl methacrylate (PMMA) nanospheres in order to determine which conditions would create the best iridescent samples. The factors affecting the iridescence were nanosphere concentration, stir rate, and processing temperature. PMMA solutions were made by adding 17 mg of granular azobis to a solution of 16 mL of distilled water with 3 mL of methyl methacrylate (MMA). The solution was stirred at different rates, slow and fast, and different temperatures, 70 °C and 90 °C, under a constant flow of nitrogen gas for 40 minutes until the polymerization reaction was complete. Glass substrates were prepared …

Preserving Wildlife In San Luis Obispo City By Way Of San Luis Obispo Creek, Sydni Nicolici

Liberal Arts and Engineering Studies

The effectiveness of San Luis Obispo wildlife easements and city open space utilized to preserve species of concern is correlated to the health and maintenance of the San Luis Obispo Creek. I propose that the health of the Creek be addressed before more open space is added to the green belt surrounding the city. This bottom-up approach to preservation will ensure all steps of habitat will function as they should.

The Nasa Glenn Research Center: An Economic Impact Study Fiscal Year 2011, Iryna Lendel, Sunjoo Park

All Maxine Goodman Levin School of Urban Affairs Publications

No abstract provided.

Constructing Simplicial Complexes Over Topological Spaces, Milka N. Doktorova

Dartmouth College Master’s Theses

The first step in topological data analysis is often the construction of a simplicial complex. This complex approximates the lost topology of a sampled point set. Current techniques often assume that the input is embedded in a metric -- often Euclidean -- space, and make significant use of the underlying geometry for efficient computation. Consequently, these techniques do not extend to non-Euclidean or non-metric spaces. In this thesis, we present an oracle-based framework for constructing simplicial complexes over arbitrary topological spaces. The framework consists of an oracle and an algorithm that builds the simplicial complex by making calls to the …

Evidence On The Human Health Effects Of Low-Level Methylmercury Exposure, Margaret R. Karagas, Anna L. Choi, Emily Oken, Milena Horvat, Rita Schoeny, Elizabeth Kamai, Whitney Cowell, Philippe Grandjean, Susan Korrick

Dartmouth Scholarship

Background: Methylmercury (MeHg) is a known neuro-toxicant. Emerging evidence indicates it may have adverse effects on the neuro-logic and other body systems at common low levels of exposure. Impacts of MeHg exposure could vary by individual susceptibility or be confounded by bene-ficial nutrients in fish containing MeHg. Despite its global relevance, synthesis of the available literature on low-level MeHg exposure has been limited.

Objectives: We undertook a synthesis of the current knowledge on the human health effects of low-level MeHg exposure to provide a basis for future research efforts, risk assessment, and exposure remediation policies worldwide.

Data sources and extraction: …

Challenges For Biological Interpretation Of Environmental Proteomics Data In Non-Model Organisms, Wesley W. Dowd

Biology Faculty Works

Environmental physiology, toxicology, and ecology and evolution stand to benefit substantially from the relatively recent surge of “omics” technologies into these fields. These approaches, and proteomics in particular, promise to elucidate novel and integrative functional responses of organisms to diverse environmental challenges, over a variety of time scales and at different levels of organization. However, application of proteomics to environmental questions suffers from several challenges—some unique to high-throughput technologies and some relevant to many related fields—that may confound downstream biological interpretation of the data. I explore three of these challenges in environmental proteomics, emphasizing the dependence of biological conclusions on …

Comparing Thigh Muscle Cross-Sectional Area And Squat Strength Among National Class Olympic Weightlifters, Power Lifters, And Bodybuilders, James J. Di Naso, Brian L. Pritschet, John D. Emmett, Jill W. Owen, Jeffrey Willardson, Travis W. Beck, Jason M. Defreitas, Fabio E. Fontana

Faculty Research and Creative Activity

Few studies have compared anthropometric characteristics among national class athletes from different resistance training disciplines, such as Olympic Weightlifting (OL), Power Lifting (PL), and Bodybuilding (BB). Objective: The purpose of the current study was to determine if significant differences exist in the relationship between thigh muscle cross-sectional area and back squat strength among national class athletes from the sports of OL, PL, and BB. Methods: Fifteen national class athletes were assessed for back squat strength, mid-thigh circumference, and mid-thigh skinfold from which total thigh cross-sectional was estimated. A series of One-Way ANOVAs and Pearson Product Moment Correlations were used to …

Notes: Red-Tailed Hawk Predation Of A Striped Skunk, Steven G. Platt, Thomas R. Rainwater

The Prairie Naturalist

Skunks (Mephitidae) are capable of projecting pungent, oily musk from paired anal glands (Verts 1967), which acts as a central nervous system depressant (Wade- Smith and Verts 1982), and can incapacitate birds of prey if directed into the eyes (Garcelon 1981). Consequently, few raptors are known to prey on striped skunks (Mephitis mephitis). Great horned owls (Bubo virginianus) are the only raptor that regularly preys on skunks (Bent 1938b, Lowery 1974, Houston et al. 1998), although occasional instances of predation by golden eagles (Aquila chrysaetos; Olendorff 1976, Palmer 1988a), bald eagles (Haliaeetus leucocephalis; Broley 1952, Wade-Smith and Verts 1982), northern …

Least And Merriam’S Shrews From Banner County, Nebraska, Jennifer N. Merlino, Alexandra R. Frohberg, Jamie Harmon, Keith Geluso

The Prairie Naturalist

Four species of shrews occur in the panhandle of western Nebraska – the masked shrew (Sorex cinereus), Merriam’s shrew (S. merriami), dwarf shrew (S. nanus), and least shrew (Cryptotis parva; Genoways et al. 2008). Little information is known regarding the distribution and habitat of those species due to few captures of individuals throughout the region (e.g., Jones 1964, Freeman et al. 1993, Benedict et al. 1999, 2000, Geluso et al. 2004). To date, no shrew has been reported from the southwestern part of the panhandle in Banner, Kimball, or Cheyenne counties. Here we present distributional records for the least shrew …

Grass And Canada Goldenrod (Solidago Canadensis) Competition And Implications For Management In The Northern Tallgrass Prairie, Alexander J. Smart, Gary E. Larson, Peter J. Bauman

The Prairie Naturalist

Canada goldenrod (Solidago canadensis L.) is a native perennial forb that can form dense clonal patches and become weedy in pastures of the Northern Tallgrass Prairie Ecoregion. Our objectives were to determine 1) the competitive effects between Canada goldenrod and grass, 2) the relationship between Canada goldenrod stem density and grass biomass, and 3) the distribution of Canada goldenrod stem density at the pasture scale. We used regression analysis to develop a relationship between Canada goldenrod stem density and grass biomass. Additionally, we estimated the frequency distribution of Canada goldenrod stem density categories using three evenly distributed 100 × 100-m …

Spatiotemporal Variation In Vegetation Structure Resulting From Pyric-Herbivory, Sherry Leis, Lloyd W. Morrison, Michael D. Debacker

The Prairie Naturalist

Pyric-herbivory is a process that is widely assumed to create greater habitat heterogeneity in grasslands at the landscape scale than could be achieved by either fire or grazing alone. Yet, few studies have actually quantified the effects of pyric- herbivory on vegetation structure within layers of the grass canopy. Here we quantify the effects of pyric-herbivory on a pasture at Tallgrass Prairie National Preserve in Kansas. We subdivided the pasture into three patches and burned one patch each year in a three-year rotation. We estimated visual obstruction for 25-cm strata and recorded maximum vegetation height. We found that recently burned …

Sickleweed On The Fort Pierre National Grassland: An Emerging Threat, Jack L. Bulter, Stefanie D. Wacker

The Prairie Naturalist

We report the first detailed field survey of sickleweed (Falcaria vulgaris L.) in the United States. Sickleweed is native to Europe, the Mediterranean, Asia Minor, and Iran and was first reported in the United States in 1922. It is listed by the Nebraska Invasive Species Council as a Category II invasive plant species. In recent years, abundance and distribution of sickle- weed has increased dramatically in and around the Fort Pierre National Grassland (FPNG), South Dakota. Management of such a rapidly expanding population is hampered by a general lack of baseline information on the biology and ecology of sickleweed. We …

Spatial Ecology Of Urban Raccoons In Northeastern Ohio: Implications For Oral Rabies Vaccination, Are R. Berentsen, Mike R. Dunbar, Chadd E. Fitzpatrick, W. David Walter

The Prairie Naturalist

In 1977, rabies was detected in a raccoon (Procyon lotor) in West Virginia, and since the mid-1980s raccoon variant rabies has spread throughout the eastern United States and moved west as far as the eastern edge of Cleveland, Ohio. The primary tool to combat this spread is the distribution of oral rabies vaccine (ORV) baits. A thorough knowledge of raccoon space use is critical in determining bait placement, particularly in urban areas. We monitored nine raccoons in urban areas of Cleveland, Ohio, calculated home range sizes, monitored raccoon movement with respect to potential movement barriers, and used resource selection functions …

The Effect Of Various Chemical Factors On Angiogenesis In The Chick Chorio-Allantoic Membrane, Heather Hammond

Theses and Dissertations

The chick chorio-allantoic membrane (CAM) contains a complex vascular network commonly used to study angiogenesis. The application of chemical factors and oxygen barrier films onto this tissue can easily influence the process of angiogenesis. In this study, oxygen barrier film patches (Krehalon, polyvinylidene chloride, 12 μm thick, O2 transmission rate = 2.19 cm3•ml/100 in2•day•atm) were applied to areas of the CAM. Holes were made in the film and alginate beads incubated in various chemical factors were placed in the holes. After 24 and 48 hours of exposure to the alginate beads, images were taken of the tissue using a stereomicroscope …

Malignant Peripheral Nerve Sheath Tumor (Mpnst): An Overview With Emphasis On Pathology, Imaging And Management Strategies, Timothy C. Beer

Department of Neurosurgery Faculty Papers

Presentation: 20 slides

MPNSTs are rare malignancies that are classically associated with pre-existing plexiform neurofibromas in neurofibromatosis type 1 (NF-1) patients, but also occur in association with radiation as well as sporadically in patients with no known risk factors. The typical presentation of sporadic MPNST is a new painless enlarging mass. The typical presentation of MPNST in an NF-1 patient is rapid enlargement or new onset of pain associated with a pre-existing plexiform neurofibroma. Although both MPNST and benign neurofibromas share in common the absence of neurofibromin function due to loss of both NF-1 alleles, malignant transformation to MPNST requires …

A Name I Call Myself: Creativity And Naming, Laura A. Heymann

Faculty Publications

In recent years, various disputes involving the use of creative works have demonstrated how trademark-related concerns lurk at the heart of what are ostensibly copyright-related claims. When recording artists such as Jackson Browne or the members of Heart object to the unauthorized use of their songs in connection with a political campaign, they are most likely not troubled about the loss of revenue resulting from the use; rather, they are likely concerned that the public will wrongly assume that the use of the song indicates that they have endorsed the political candidate. But because it is sometimes easier for them …

Glutathione-Mediated Neuroprotection Against Methylmercury Neurotoxicity In Cortical Culture Is Dependent On Mrp1, Travis Rush, Xiaoqian Liu, Andrew B. Nowakowski, David H. Petering, Doug Lobner

Biomedical Sciences Faculty Research and Publications

Methylmercury (MeHg) exposure at high concentrations poses significant neurotoxic threat to humans worldwide. The present study investigated the mechanisms of glutathione-mediated attenuation of MeHg neurotoxicity in primary cortical culture. MeHg (5 μM) caused depletion of mono- and disulfide glutathione in neuronal, glial and mixed cultures. Supplementation with exogenous glutathione, specifically glutathione monoethyl ester (GSHME) protected against the MeHg induced neuronal death. MeHg caused increased reactive oxygen species (ROS) formation measured by dichlorodihydrofluorescein (DCF) fluorescence with an early increase at 30 min and a late increase at 6 h. This oxidative stress was prevented by the presence of either GSHME or …

Of Heart, Mind & Belonging: Reflections On Anti-Racist White Identity Development, Jessica V. Havens

College of Liberal Arts & Social Sciences Theses and Dissertations

Anti-racist white activists have actively participated within movements for racial justice in the United States, in both the pre-and post-civil rights era. Inspired by the voices, work and leadership of people of color, as well as through multiracial coalition building, anti-racist white activism has taken many forms over the years. In some instances, this activism has involved educating and engaging with other white people in examining their white privilege and strategies for accountability, as a means for incorporating an awareness of whiteness and privilege into their multiracial social justice organizing. This thesis examines the stories of present-day white anti-racists in …

Roles Of Resveratrol And Genistein In Invasion And Metastasis Of Breast Cancer, Brittany Wolfe

College of Science and Health Theses and Dissertations

Breast cancer is a cellular disease characterized by the exploitation of several cellular and molecular mechanisms involved in cell proliferation, apoptosis, motility, and invasion. Effective treatment is available for non-invasive breast cancer at diagnosis, leading to a very high survival rate compared to the low survival rate for those where the breast cancer has spread. Thus, identifying effective therapies and preventative agents is imperative to successfully treat breast cancer. Since diet compromises a large component of the risk factors for breast cancer, it would be beneficial to examine dietary compounds that could potentially play a beneficial role in inhibiting cancer …

There's No Place Like Home: Realizing The Vision Of Community-Based Mental Health Treatment For Children, Yael Zakai Cannon

DePaul Law Review

No abstract provided.

Mid-Twentieth Century Residential Development In San Luis Obispo, Allison Dean Zike

Master's Theses

San Luis Obispo’s mid-century spanned the years beginning in the Great Depression and ending during the post-World War II housing boom. During this time the City grew in population and in size, adding several acres of land and thousands of single-family residential parcels. This research presents a chronological representation of the City’s growth, as well as key events in the City’s history. Residential development in the mid-century brought several new styles of architecture to the City including Mid-century Modern and Prairie homes among others. These architectural styles are detailed and presented in order to identify and guide the preservation of …

Growing Gardens: Botanical Gardens, Public Space And Conservation, Terra Celeste Colburn

Master's Theses

This thesis examines the history of botanical gardens and their evolution

from ancient spaces to the modern gardens of the 20th century. I provide a brief

overview of botanical gardens, with a focus on the unique intersection of public

participation and scientific study that started to occur within garden spaces during

the 20th century, which still continues today. I reveal the history of gardens that

influenced the uses of gardens today, with a focus on: the first ancient gardens

and the dependency societies had on them, the influence of science in gardens

starting in the Enlightenment period, the shift away …

Assessment Of Site And Soil Characteristics Of Rill Erosion Following The Lockheed Fire In The Little Creek Watershed, Swanton Pacific Ranch, Lynette Kristine Niebrugge

Master's Theses

The Lockheed Fire occurred in August 2009, burning 7,819 acres of the coastal mountains north of Santa Cruz, California. The fire burned a large portion of the Scotts Creek watershed, including over 90 % of the Little Creek watershed, much of which is on Cal Poly’s Swanton Pacific Ranch (SPR). After intense winter rains in 2010 there was a significant amount of hillslope-derived sediment deposited on the roads and in the creek. A large portion of this material was derived from two chaparral hillslopes. These hillslopes were identified as the only two hillslopes within the Little Creek subwatershed where an …

Application Of A Heuristic Method To A Water Distribution System For Determining Optimal Water Quality Monitoring Locations, Lawrence David Johnson

Master's Theses

Although regulations and requirements for water quality source monitoring have increased, drinking water distribution systems can still be considered vulnerable to purposeful or accidental contamination.

This study analyzes the transport of the hypothetical contaminant Cryptosporidium through the distribution system of a city with a population of 30,000 to 50,000 in an attempt to locate the optimal monitoring locations in the distribution system. Cryptosporidium was selected due to its resistance to chlorine and it’s conservative properties for vulnerability assessments. The method for selecting the optimal monitoring locations was taken from Chastain (2004) which developed and examined the method for a virtual …

A New Computational Model To Augment The Design Of Microfluidic Separations: Electric Field Assisted, Hydrodynamic Chromatography, Jeffrey D. Wells

Master's Theses

This project encompasses the implementation of a computational model to simulate the microfluidic separation of like-charged particles in a continuous flow environment. By accomplishing this task the model can be used to optimize future fractionations by tailoring the process parameters to the properties of the target particles. The primary goal of this project is to develop a vectorized code within Matlab® that captures a sufficient quantity of the physics in separations to assist with the optimization and design of microfluidic systems.

This project differs from other computational models in that it utilizes a personal computer to run the simulation in …

Cascaded High Voltage Converter With Variable Control For Pulsed Electric Field Applications, Emmanuel Loza

Master's Theses

Living a sustainable lifestyle while facing increasing population and decreasing natural resources has become one of humanity’s largest challenges. Locating fossil fuels is becoming more difficult while the demand for them to power our societies is ever increasing. Instead of finding more efficient methods of extracting fossil fuels, developing technologies that create renewable substitutes for fossil fuels is now the strategy. Algae biofuel matches fossil fuel performance while also meeting the criteria for renewable energy. The focus now shifts to finding methods for commercially producing algae biofuel. Therefore, the objective of this thesis is to develop a system that provides …

Feasibility Study Into The Use Of 3d Printed Materials In Cubesat Flight Missions, Daniel Fluitt

Master's Theses

The CubeSat Program has provided access to space for many universities, private companies, and government institutions primarily due to the low cost of CubeSat satellite development. While these costs are orders of magnitude lower than similarly capable nano-satellite missions, they are still outside of the budgetary constraints of many potential developers including university and high school clubs. Using 3D printed plastics in the production of CubeSat structures and mechanisms presents a large cost savings opportunity that will allow these institutions to participate in the development of these satellites, expanding the educational and scientific impact of the CubeSat Program.

Five rapid …

The Characterization Of Biofilm Attachment To Metal Interfaces: Effects Of Substratum Properties, Marcel D. Mendes

Master's Theses

Bacteria are among the most abundant microorganisms on earth, and can be found in essentially every environment. When a clean surface is exposed to media containing planktonic bacteria, the bacterial cells will attach to the surface and aggregate to form what is known as a biofilm. Biofilms have been shown to negatively affect many industries including medical, industrial, and food science applications. While biofilms have been well characterized from a microbiology perspective, there has been much less research from a materials science standpoint. It is hypothesized that the material properties of the substratum (such as the micro-structure) have a significant …

Preparation And Characterization Of Electrospun Poly(D, L-Lactide-Co-Glycolide) Scaffolds For Vascular Tissue Engineering And The Advancement Of An In Vitro Blood Brain Barrier Model, Deven Chandrakant Patel

Master's Theses

Developing an in vitro Blood Brain Barrier model that will replicate the physiological, anatomical, and functional characteristics of the native BBB has gained significant attention. Such a model would enable prediction of the penetration of CNS targeting drug candidates across the BBB, allow pre-screening and optimization strategies to be developed for new drugs and gene delivery formulations, and permit research groups to further understand how a dysfunctional BBB is involved in the pathogenesis of several neurological diseases.

The Tissue Engineering laboratory at the California Polytechnic State University, San Luis Obispo is currently in the process of developing a dynamic in …

A Proteomic Analysis Of Differentiation In The Mammary Epithelium, Laura Therese Strand

Master's Theses

While a great deal is known about the changing hormonal environment and the structural development of the mammary gland from pregnancy to lactation, very little is known about the molecular mechanisms governing differentiation of the mammary epithelium into a milk-secreting phenotype. It is important to acknowledge the diversity among the mammary glands of different species in order to better understand applications in human health and the dairy industry. In this study, we examined global protein expression during two states of differentiation in mammary epithelial cells from two species: in vitro proliferating and differentiated MAC-T cells (a bovine immortal cell-line), and …