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Faculty Senate Meeting Agenda And Minutes, June 4, 2012

Faculty Senate Minutes and Agendas

Agenda and minutes from the Wright State University Faculty Senate Meeting held on, June 4, 2012.

Selective Impact Of Hiv Disease Progression On The Innate Immune System In The Human Female Reproductive Tract., Timothy Lahey, Mimi Ghosh, John V. Fahey, Zheng Sheng, Lucy R. Mukura, Yan Song, Susan Cu-Uvin, Kenneth H. Mayer, Peter F. Wright, John C. Kappes, Christina Ochsenbauer, Charles R. Wira

Epidemiology Faculty Publications

Background

We have previously demonstrated intrinsic anti-HIV activity in cervicovaginal lavage (CVL) from HIV-infected women with high CD4 counts and not on antiretroviral therapy. However, the impact of HIV disease progression on CVL innate immune responses has not been delineated.

Methods

CVL from 57 HIV-infected women not on antiretroviral therapy were collected by washing the cervicovaginal area with 10 ml of sterile normal saline. We characterized subject HIV disease progression by CD4 count strata: >500 cells/µl, 200–500 cells/µl, or <200 cells/µl of blood. To assess CVL anti-HIV activity, we incubated TZM-bl cells with HIV plus or minus CVL. Antimicrobials, cytokines, chemokines and anti-gp160 HIV IgG antibodies were measured by ELISA and Luminex.

Results

CVL exhibited broad anti-HIV activity against multiple laboratory-adapted and transmitted/founder (T/F) viruses, with anti-HIV activity ranging from 0 to 100% …

Exposure To Dietary Selenium And Soy Isoflavones In Utero Provides Greater Protection Against Prostate Cancer Risk Factors In Tramp Mice Than Exposure Beginning At 6 Weeks, Heather Schofield Lindsay

Theses and Dissertations

Prostate cancer is the second most commonly occurring cancer in men in the United States. Generally, an extended period of time is needed for a mutation to develop into a full scale tumor. Because of this long latency period, lifestyle and environmental factors, such as diet, may play an important role in the development and progression of the disease. Diet is one factor that has been implicated in the risk for developing prostate cancer. We previously showed that diets high in soy isoflavones and selenium (Se) decreased androgen receptor expression and expression of androgen regulated genes in healthy rat prostates. …

Optimizing Pentose Utilization In Clostridia For Improved Solvents Production From Lignocellulosic Hydrolysates, Sheng Yang

Metabolic Engineering IX

No abstract provided.

Coordinating Environmental Genomics And Geochemistry Reveals Metabolic Transitions In A Hot Spring Ecosystem, Wesley D. Swingley, D'Arcy R. Meyer-Dombard, Everett Shock, Eric B. Alsop, Heinz D. Falenski, Jeff R. Havig, Jason Raymond

Faculty Articles, Papers, and Other Scholarship

We have constructed a conceptual model of biogeochemical cycles and metabolic and microbial community shifts within a hot spring ecosystem via coordinated analysis of the ‘‘Bison Pool’’ (BP) Environmental Genome and a complementary contextual geochemical dataset of ,75 geochemical parameters. 2,321 16S rRNA clones and 470 megabases of environmental sequence data were produced from biofilms at five sites along the outflow of BP, an alkaline hot spring in Sentinel Meadow (Lower Geyser Basin) of Yellowstone National Park. This channel acts as a .22 m gradient of decreasing temperature, increasing dissolved oxygen, and changing availability of biologically important chemical species, such …

Shaping The Way Of Instruction: Fusion Of Games, Lecture And Theatrical Techniques Vs. Traditional Lecture Type Of Library Instruction: Examining Its Effectiveness In Undergraduate Library Instruction, Harold T. Franco, Bob P. Cauilan

Proceedings of the IATUL Conferences

Nowadays, traditional lecture type of library instruction may work only to few audiences. Students exhibit various learning styles and along with this instruction, librarians are also faced with users of new generations. Users who are capable of multitasking, tech-savvy and are more inclined to surfing the net and engaging much on online chat, Internet discussion forums and online games, may find traditional type of instructions ineffective and boring.

In order to give an answer to the effectiveness of the library instruction being conducted in each term at the De La Salle University –Manila, a study has been made to compare …

Magnet: Microarray Gene Expression And Network Evaluation Toolkit, George C. Linderman, Mark R. Chance, Gurkan Bebek

Faculty Scholarship

MicroArray Gene expression and Network Evaluation Toolkit (MAGNET) is a web-based application that provides tools to generate and score both protein-protein interaction networks and coexpression networks. MAGNET integrates user-provided experimental measurements with high-throughput proteomic datasets, generating weighted gene-gene and protein-protein interaction networks. MAGNET allows users to weight edges of protein-protein interaction networks using a logistic regression model integrating tissue-specific gene expression data, sub-cellular localization data, co-clustering of interacting proteins and the number of observations of the interaction. This provides a way to quantitatively measure the plausibility of interactions in protein-protein interaction networks given protein/gene expression measurements. Secondly, MAGNET generates filtered …

State V. Schulz Appellant's Brief Dckt. 39000

Not Reported

No abstract provided.

Selective Impact Of Hiv Disease Progression On The Innate Immune System In The Human Female Reproductive Tract, Timothy Lahey, Mimi Ghosh, John V. Fahey, Zheng Shen, Lucy R. Mukura, Yan Song, Susan Cu-Uvin, Kenneth H. Mayer, Peter F. Wright, John C. Kappes, Christina Ochsenbauer, Charles R. Wira

Dartmouth Scholarship

Background: We have previously demonstrated intrinsic anti-HIV activity in cervicovaginal lavage (CVL) from HIV-infected women with high CD4 counts and not on antiretroviral therapy. However, the impact of HIV disease progression on CVL innate immune responses has not been delineated.

Methods: CVL from 57 HIV-infected women not on antiretroviral therapy were collected by washing the cervicovaginal area with 10 ml of sterile normal saline. We characterized subject HIV disease progression by CD4 count strata: >500 cells/µl, 200-500 cells/µl, or <200 cells/µl of blood. To assess CVL anti-HIV activity, we incubated TZM-bl cells with HIV plus or minus CVL. Antimicrobials, cytokines, chemokines and anti-gp160 HIV IgG antibodies were measured by ELISA and Luminex.

Effect Of Antioxidants And Oxidative Stress On Different Cancer Cell Types, Gaytri Devi Gupta Elera

Theses and Dissertations

Vaccinium cyanococcus, most commonly known as blueberry, is a fruit native to North America that is known for its unique taste and high antioxidant content. The skin, seed and juice of both organically and conventionally grown blueberry extract were analyzed for antioxidant content using both the Hydrophilic and Lipophilic Oxygen Radical Absorbance Capacity (ORAC) assays. Results from the Hydrophilic ORAC test showed that conventionally grown blue berries had a higher antioxidant capacity across all samples, while the Lipophilic ORAC assay showed that the antioxidant concentration of organically cultivated blueberry juice was highest, but conventionally grown blueberry seed and skin …

Yale’S Partnership Against Huntington’S Disease: An Alumnus Reconnects And Finds Hope As Scientists Pursue 'Viagra For The Brain' And Other Solutions, Kenneth P. Serbin

At Risk for Huntington's Disease

No abstract provided.

Wright State Core With Iw And Mc Designations And List Of Course Syllabi

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A list of Wright State Core designations, class titles, and links to course syllabi.

Medical School Watercooler Newsletter - June 3, 2012, Lindsey Lyle

Watercooler Newsletter

This is the June 3, 2012 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA College of Medicine Scientists Receive Historic $9 Million Research NIH Grant
• Community Leaders, Residents Meet at USA Medical Center to Discuss Crichton Beautification Initiative
• Snapshots: 1st Lung Bowl Competition
• Mark Your Calendars: AOA Visiting Professorship Lectures

The Emotions And Two Aesthetic Paradoxes, Nicholas James Curry

Theses

The purpose of this paper is to show that the shape of the dispute over a central issue in the philosophy of emotion—namely, the disagreement over the role of cognition in emotion—provides a useful way of seeing the twin aesthetic paradoxes of horror and tragedy. Recent theories of emotion can be helpfully divided into two camps, the affective and the cognitive. Affective theories hold that emotions consist of bodily affect alone, and are therefore cognitively impenetrable. Cognitive theories hold that emotions are or entail cognition. To discuss the differences between affective and cognitive views, I consider the theories of Jesse …

Developing Industrial Biotechnology Through Partnerships, Vincent Schachter

Metabolic Engineering IX

No abstract provided.

Conference Program, Engineering Conferences International

Metabolic Engineering IX

No abstract provided.

Genomics Based Engineering For The Identification And Optimization Of Bioactive Microbial Natural Products, Rolf Müller

Metabolic Engineering IX

No abstract provided.

Semester Courses And Course Equivalents: Graduate Courses Summary

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A list comprised of summaries of all graduate courses and course equivalents at Wright State University.

Semester Courses And Course Equivalents: Graduate Courses Detailed

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A list detailed information about all graduate courses and course equivalents at Wright State University.

Semester Courses And Course Equivalents: All Undergraduate Courses Detailed

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A list detailed information about all undergraduate courses and course equivalents at Wright State University.

Summary Cognos Program Files: Undergraduate Programs

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A summary list of all undergraduate programs at Wright State University.

College Admission Requirements Policies: Cosm

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A list of college admission requirements for quarters and semesters for the College of Science and Mathematics at Wright State University.

Summary Cognos Program Files: Graduate Programs

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A summary list of all graduate programs at Wright State University.

Semester Courses And Course Equivalents: All Undergraduate Courses Summary

Undergraduate Curriculum and Academic Policy Committee Wright State University Quarter to Semester Transition

A list comprised of summaries of all undergraduate courses and course equivalents at Wright State University.

Caudate Nucleus Volume Mediates The Link Between Cardiorespiratory Fitness And Cognitive Flexibility In Older Adults, Timothy D. Verstynen, Brighid Lynch, Destiny L. Miller, Michelle W. Voss, Ruchika Shaurya Prakash, Laura Chaddock, Chandramallika Basak, Amanda Szabo, Erin A. Olson, Thomas R. Wojcicki, Jason Fanning, Neha P. Gothe, Edward Mcauley, Arthur F. Kramer, Kirk I. Erickson

Kinesiology, Health and Sport Studies

The basal ganglia play a central role in regulating the response selection abilities that are critical formental flexibility. In neocortical areas, higher cardiorespiratory fitness levels are associated with increased gray matter volume, and these volumetric differences mediate enhanced cognitive performance in a variety of tasks. Here we examine whether cardiorespiratory fitness correlates with the volume of the subcortical nuclei that make up the basal ganglia and whether this relationship predicts cognitive flexibility in older adults. Structural MRI was used to determine the volume of the basal ganglia nuclei in a group of older, neurologically healthy individuals (mean age 66 years, …

Herbaceous 2012 (June 3), Amy L. Myers, Julia I. Chapman, Ryan W. Mcewan

Data Files: Drew Woods Permanent Plots

Herbaceous vegetation data collected in 2012 at Drew Woods State Nature Preserve in Darke County, OH. Data key is provided in a supplemental file.

A Biochemical Study For Evaluation And Analysis Of Serum Protein Of Patients With Different Kidney Tumors, Rasha Hassan Jsiem, Hathama Razoki Hasan, Majid Kadhum Husain

Baghdad Science Journal

The amount of protein in the serum depends on the balance between the rate of its synthesis, and that of its catabolism or loss. Abnormal metabolism may result from nutritional deficiency, enzyme deficiency, abnormal secretion of hormones, or the actions of drugs and toxins. Renal cancer is the third most common malignancy of the genitourinary system, and accounts for 3% of adult malignancies globally. Total serum proteins were measured in malignant kidney tumor, benign kidney tumors, and non tumoral kidney diseases patient groups, as well as in healthy individuals. A significant decrease (p< 0.001) of total serum protein levels in patients with malignant kidney tumors when compared with those of benign tumors, non tumoral diseases, and healthy individuals. The lowest serum protein levels were found in patients with stage IV, regardless their genders. Analysis of total serum proteins using PAGE revealed clear differences in the number and shape of the bands in patients with different kidney diseases compared with healthy controls.

Study The Effect Of The Mixture Aquatic Extract Of Peganum Harmala Seeds And Pericarp Of Punica Granutum On Viability Of Protoscolices Of Echinococcus Granulosus In Vitro And In Vivo, Fawzia Ahmed Al-Shanawi, Noor Nihad Baker, Amjed Qays Ibrahim

Baghdad Science Journal

This study included the preparation of the mixture aquatic extracts of Peganum harmala seeds and Pericarp of Punica granutum at concentration (10+50) ?(15+55)? (20+60) mgml .To study the influence of the mixture on the percentage of vitality of the protoscolices of E. granulosus In vitro, as the vitality of protoscolices had caused complete death when the using concentration at time 120,90,60 minute respectively. Also study the effect of mixture in white mice with infectious protoscolices In vivo and study the change occurred in the averages of the weights of the liver and spleen and the averages of its distension In …

Study Of Liver And Kidney Functions In Non-Pregnant, Pregnant And Preeclamptic Women, Zainab G. Hussein

Baghdad Science Journal

Three groups of subjects have been divided (25/group):healthy normotensive non-pregnant women (Group A), normal normotensive pregnant women (Group B), and women with preeclampsia (Group C).The levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST),total bilirubin , creatinine , blood urea nitrogen,triglyceride , totalcholesterol and glucose have beenestimated in all subjects.All measuredparameters were determined by spectrophotometric analysis. The results showed a significant(P<0.05) increase in serum ALT, AST,blood urea nitrogen,triglyceride and total cholesterol levels in group B as compared to group A. However creatinine, total bilirubin and glucose levels did not show any statisticalsignificant alterations. The women in group C showed to beassociated with a significant(P<0.05) rise in all measured parameters except total bilirubin as compared towomenin group A.The preeclamptic women (group C)showed significant (P<0.05)increase in serum alanine aminotransferase , blood urea nitrogen , triglyceride , total cholesterol and glucose levels as compared to womenin groupB. While serum aspartate aminotransferase, total bilirubinand creatinine levels did not show any statisticalsignificant alteration.(P

Evaluation The Levels Of Serum Hormones (Progesterone, Estradiol, And Hcg) In Preeclamptic Iraqipregnancies, Suaad A. Brakhas, Abbass M. Rahmah, Amna N Jassim

Baghdad Science Journal

This study aimedto evaluate serumlevels of steroid hormones and human chorionic gonadotropin (hCG) hormonein preeclamptic Iraqi pregnancies compared to those of healthy pregnancies.This study enrolled 120 pregnant women, divided into four groups:1.30 healthy pregnant women.2.37 pregnant women with mild preeclampsia3.53 pregnant women with severe preeclampsia4.90 pregnant women with preeclampsiaPreeclamptic women and their severe cases but not mild caseshad significantly(P<0.01)increased levels of serumhCGas compared with healthy pregnancies. By contrast, seralevels of estradiolwere significantly (P<0.01) decreasedin total preeclamptic groups and their severe cases but not in mild group as compared tohealthy pregnant women(controls) , while there were no significant differences in the levels of serum progesterone in all preeclamptic groups as compared with controls.This study that concludes Preeclampsia is associated with increased levels of hCG hormone and decreased levels of estradiol hormone and these support thesuggestion of the role of hormonesin preeclampsia.