Digital Commons Network^™

Second Graders’ Recycled/Craft Item Products Demonstrate Life Cycle Content Knowledge And Creativity Skills, Angela Naomi Webb, Audrey C. Rule

Curriculum & Instruction Faculty Publications

Creativity is a necessary skill for students to become problem solvers in the rapidly changing 21^st century. This study’s main activity allowed students to demonstrate their content knowledge in an engaging way while also exhibiting creative strengths. Twenty-two second grade students (15 female, 7 male) of mixed ability levels at a Title 1 school produced projects using identical sets of recycled and craft items. They incorporated vocabulary words and images associated with the life cycles of four organisms: horse, dragonfly, sea turtle, and bean plant. Projects were analyzed for creative strengths as well as science concept integration. Student-made products …

Responses Of Common Diving Petrel Chicks (Pelecanoides Urinatrix) To Burrow And Colony Specific Odours In A Simple Wind Tunnel, Gregory B. Cunningham, Richard W. Van Buskirk, Mark J. Hodges, Gabrielle A. Nevitt

Biology Faculty/Staff Publications

Researchers have previously assumed that common diving petrels (Pelecanoides urinatrix) have a limited sense of smell since they have relatively small olfactory bulbs. A recent study, however, showed that adult diving petrels prefer the scent of their own burrow compared to burrows of other diving petrels, implying that personal scents contribute to the burrow’s odour signature. Because diving petrels appear to be adapted to use olfaction in social contexts, they could be a useful model for investigating how chemically mediated social recognition develops in birds. A first step is to determine whether diving petrel chicks can detect familiar and unfamiliar …

Graduate Catalog. 2012, Fall., University Of Mississippi. Graduate School

Catalogs

No abstract provided.

Managed Relocation: Integrating The Scientific, Regulatory, And Ethical Challenges, Mark W. Schwartz, Jessica J. Hellmann, Jason M. Mclachlan, Dov F. Sax, Justin O. Borevitz, Jean Brennan, Alejandro E. Camacho, Gerardo Ceballos, Jamie R. Clark, Holly Doremus, Regan Early, Julie R. Etterson, Dwight Fielder, Jacquelyn L. Gill, Patrick Gonzalez, Nancy Green, Lee Hannah, Dale W. Jamieson, Debra Javeline, Ben A. Minteer, Jay Odenbaugh, Stephen Polasky, David M. Richardson, Terry L. Root, Hugh D. Safford, Osvaldo Sala, Stephen H. Schneider, Andrew R. Thompson, John W. Williams, Mark Vellend, Pati Vitt, Sandra Zellmer

Nebraska College of Law: Faculty Publications

Managed relocation is defined as the movement of species, populations, or genotypes to places outside the areas of their historical distributions to maintain biological diversity or ecosystem functioning with changing climate. It has been claimed that a major extinction event is under way and that climate change is increasing its severity. Projections indicating that climate change may drive substantial losses of biodiversity have compelled some scientists to suggest that traditional management strategies are insufficient. The managed relocation of species is a controversial management response to climate change. The published literature has emphasized biological concerns over difficult ethical, legal, and policy …

Sillica Nanoporous Materials Adsorption And Release Study, Gang Wang

Chemistry - Dissertations

The lower efficiency of the current common ways of delivering drugs to humans like oral administration and injection make it necessary to find more efficient delivery systems. In this regard, a class of nanostructured materials called mesoporous silicates such as MCM-41, SBA-15 has attracted the attention of many scientists as drug delivery vehicles for their outstanding features like high surface area, high porosity, well-ordered, tunable nanometer pores and "non-cytotoxic" properties.

In this dissertation, comparative investigations of the adsorption capacity and drug release properties of these materials whose surfaces were functionalized with judiciously chosen organic groups via either post-grafting or co-condensation …

Wednesday Communiqué, 8/1/2012, Chaouki Abdallah

Publications of the Provost's Office

The One Question We Should Ask: I read recently that each organization needs to have one question that can guide it through challenges and changes. I believe that UNMs question should be: Is it good for our students?'

Evaluation Of The Effects Of September Hunting Seasons On Canada Geese In Nebraska, Scott R. Groepper, Mark P. Vrtiska, Larkin A. Powell, Scott E. Hygnstrom

School of Natural Resources: Faculty Publications

Populations of temperate-nesting Canada geese (Branta canadensis) have increased in Nebraska, USA, resulting in an increased number of nuisance and damage complaints. September hunting seasons were initiated in southeastern Nebraska in 2004 to reduce populations of Canada geese. We analyzed band recoveries from Canada geese banded in southeastern Nebraska during their hatch-year (HY) or after-hatch-year (AHY) to determine whether September hunting seasons affected survival, harvest, and recovery rates. Survival analyses revealed that HY geese had higher survival than AHY geese (SAHY = 0.696, 95% CI = 0.679–0.713; SHY = 0.896, 95% CI = 0.786–0.953) and September seasons did …

Undergraduate Catalog - The School Year 2012-2013, Prairie View A&M University

Undergraduate Catalog

No abstract provided.

Department Of Chemistry News, Fall 2012, Illinois State University, Department Of Chemistry

Chem Letter

Newsletter of the Illinois State University Department of Chemistry

Bulletin Ammp Centre, Issue 3, 2012, Faculty Of Engineering University Of Malaya

Archival Material (2010s)

No abstract provided.

Fabrication And Characterization Of Thermomechanically Processed Sulfur And Boron Doped Amorphous Carbon Films, Lonnie Carlson

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Small scale, high power density, reliable, and long-life power supplies would be useful or even critical for space missions or the growing number of microdetectors, microsensors, and miniature vehicles. Alpha or beta particle voltaic devices could satisfy these requirements but have been shown to degrade quickly due to radiation damage. Amorphous carbon (a-C) PN junctions or PIN devices could provide radiation hardness and sufficiently high efficiency. As the range of alpha and beta particles in a-C is ~20-120μm, much thicker films than are typical are needed to maximize collection of the particle energy.

In this work, the fabrication of thermomechanically …

2012-13 Graduate Bulletin

Graduate Bulletins

After 2003 the University of Dayton Bulletin went exclusively online. This copy was downloaded from the University of Dayton's website.

A New Algorithm For Dna Motif Detection, Ran Ding

Theses and Dissertations - UTB/UTPA

Nowadays, people are more and more concentrated on the research of deoxyribonucleic acid(DNA). And a very important problem is how to identify the DNA performance. A DNA sequence contains lots of genes, and every gene has a regulatory region. This regulatory region contains the transcription factor binding sites (TFBS) which is also known as motif. How to identify this motif becomes a very important problem. There are many efficient methods and tools are dedicated to the research of DNA motif detection. In this paper, we will introduce a new method of DNA motif detection which basically is an advanced approximate …

The Neurobiology Of Attachment To Nurturing And Abusive Caregivers, Regina M. Sullivan

UC Law Journal

Decades of research have shown that childhood experiences interact with our genetics to change the structure and function of the brain. Within the range of normal experiences, this system enables the brain to be modified during development to adapt to various environments and cultures. Experiences with and attachment to the caregiver appear particularly important, and recent research suggests this may be due, in part, to the attachment circuitry within the brain. Children have brain circuitry to ensure attachment to their caregivers. Attachment depends on the offspring learning about the caregiver in a process that begins prenatally and continues through most …

Augf2012, Robert Kelly

Robert Kelly Manuscripts

From August 2012 Robert Kelly Archives

Breastfeeding Success Among Infants With Phenylketonuria, Sandra Banta-Wright, Kathleen C. Shelton, Nancy D. Lowe, Kathleen A. Knafl, Gayle M. Houck

Faculty Publications - College of Nursing

Breast milk is the nutrition of choice for human infants (American Academy of Pediatrics, 2005; American Association of Family Physicians, 2008; Association of Women’s Health Obstetric and Neonatal Nurses, 2005; Canadian Paediatric Society, 2005; U.S. Preventive Services Task Force, 2008; World Health Organization, 2009). The literature on the benefits of breast milk and breastfeeding for infants and mothers has established multiple positive outcomes for infants (Hoddinott, Tappin, & Wright, 2008; Horta, Bahl, Martines, & Victora, 2007; Ip et al., 2007). Breast milk has advantages for infants that distinguish it from standard commercial infant formulas. These advantages include growth factors, hormones, …

Pnpla3 Polymorphisms And Liver Aminotransferase Levels In A Mexican American Population, Quan Li, Hui-Qi Qu, Anne R. Rentfro, Megan L. Grove, S. Mirza, Yang Lu, Craig Hanis, Michael B. Fallon, Eric Boerwinkle, Susan P. Fisher-Hoch, Joseph B. Mccormick

School of Nursing Faculty Publications

Purpose: This study examined genetic associations of patatin-like phospholipase domain containing 3 gene (PNPLA3) polymorphisms and liver aminotransferases in an extensively documented, randomly recruited Mexican American population at high risk of liver disease.

Methods: Two single nucleotide polymorphisms (SNP) in the PNPLA3 gene (i.e., rs738409 and rs2281135) were genotyped in 1532 individuals. Population stratification was corrected by the genotyping of 103 ancestry informative markers (AIMs) for Mexican Americans.

Results: Both PNPLA3 SNPs showed highly significant association with alanine aminotransferase (ALT) levels, but was also, in males, associated with aspartate aminotransferase (AST) levels. Haplotypic association test of the two SNPs suggested …

Population-Based Risk Factors For Elevated Alanine Aminotransferase In A South Texas Mexican-American Population, Hui-Qi Qu, Quan Li, Megan L. Grove, Yang Lu, Jen-Jung Pan, Anne R. Rentfro, Perry E. Bickel, Michael B. Fallon, Craig L. Hanis, Eric Boerwinkle, Joseph B. Mccormick, Susan P. Fisher-Hoch

School of Nursing Faculty Publications

Background and aims: Elevated alanine aminotransferase (ALT >40 IU/mL) is a marker of liver injury but provides little insight into etiology. We aimed to identify and stratify risk factors associated with elevated ALT in a randomly selected population with a high prevalence of elevated ALT (39%), obesity (49%) and diabetes (30%).

Methods: Two machine learning methods, the support vector machine (SVM) and Bayesian logistic regression (BLR), were used to capture risk factors in a community cohort of 1532 adults from the Cameron County Hispanic Cohort (CCHC). A total of 28 predictor variables were used in the prediction models. The recently …

Understanding The Molecular Determinants Of Substrate And Inhibitor Specificities In The Carbapenemase Kpc-2: Exploring The Roles Of Arg220 And Glu276

Chemistry Faculty Publications

β-Lactamases are important antibiotic resistance determinants expressed by bacteria. By studying the mechanistic properties of β-lactamases, we can identify opportunities to circumvent resistance through the design of novel inhibitors. Comparative amino acid sequence analysis of class A β-lactamases reveals that many enzymes possess a localized positively charged residue (e.g., R220, R244, or R276) that is critical for interactions with β-lactams and β-lactamase inhibitors. To better understand the contribution of these residues to the catalytic process, we explored the roles of R220 and E276 in KPC-2, a class A β-lactamase that inactivates carbapenems and β-lactamase inhibitors. Our study reveals that substitutions …

Histomorphometric Differences In Tibial Cortical Bone Based On Sampling Location, Stepahnie Nicole Blatch

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Histomorphometric analysis of cortical bone is often used to estimate age at death of skeletons or to make inferences about mobility in past populations. Although previous studies have indicated that remodeling is variable within a single cross-section of bone, there has been little examination of the nature of these differences in the human tibia. This study investigated whether there are differences in remodeling based on sampling location in human tibiae, specifically examining inter-quadrant differences (anterior, posterior, medial, and lateral) as well as differences between periosteal, endosteal, and midcortical sampling locations. Slides of undecalcified sections of human tibiae at midshaft (N=10) …

Breaking The Genomic Cis-Regulatory Code By An Experimental And Theoretical Analysis Of Eve Enhancer Fusions, Ah-Ram Kim

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Encoded within DNA sequence is the cis-regulatory logic responsible for controlling gene expression in metazoans. The precise and predictive decryption of this code is on going endeavor at the heart of modern genomics. Even though state of the art technologies in genomics have been generated tremendous amount of data, how the interplay of multiple transcriptional mechanisms give rise to the complex expression changes has remain elusive. This dissertation presents a theoretical model that reconstitutes even-skipped transcriptional control in silico by implementing molecular regulatory mechanisms that are essential for the even-skipped gene expression, then applies the model to even-skipped enhancer fusions …

Morphological Correlates Of Primate Hallucal Grasping, Katherine Elizabeth Goodenberger

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Primates are unusual among mammals in having a well-developed hallucal grasping mechanism. Hallucal grasping has been featured in many adaptive scenarios of primate evolution. Some authors have suggested that primates possess more powerful hallucal grasping than non-primate euarchontans and that there are variations in hallucal grasping power and grasping type among primates. In these scenarios, powerful grasping is associated with the use of different substrate size and orientation and some authors have argued that these differences should be reflected in the morphology of the hallucal metatarsal (Mt1). Using data taken from the primate behavior literature, this thesis examines the morphology …

Cis-Regulatory Contributions To The Regulation Of Sloppy-Paired 1 Transcription Initiation And Elongation, Saiyu Hang

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

The expression of the sloppy-paired 1 (slp1) gene in the gastrula stage Drosophila embryo is controlled by the interplay of four transcription factors Runt, Even-skipped (Eve), Fushi-tarazu (Ftz), and Odd-paired (Opa) with two distinct cis-regulatory enhancer elements, the distal early stripe element (DESE) and the proximal early stripe element (PESE). The stripe pattern of slp1 is the result of non-additive interactions between these two enhancers and is context-dependent. Using chromatin immunoprecipitation (ChIP) to examine a number of reporter constructs, I found DESE mediates Runt dependent activation by facilitating pre-initiation complex formation on the slp1 promoter. This DESE-dependent activation is influenced …

Transmembrane Domain Structure And Function In The Erythropoietin Receptor, Ian Christopher Brett

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Activation of the erythropoietin receptor (EpoR) by the soluble cytokine erythropoietin (Epo) is essential for the differentiation of erythrocyte progenitors and their development into red blood cells. The single transmembrane (TM) helix of the EpoR mediates dimerization of the receptor in the inactive state and is responsible for coupling ligand binding to activation of an intracellular Janus kinase. Neither the structure of the inactive dimer nor the structural changes in the TM region that occur upon ligand binding are known. This work presents the solution NMR structures of peptides corresponding to the TM and juxtamembrane (JM) sequences that bridge the …

Novel Ways To Generate Polypropionates For The Synthesis Of Polyketide Natural Products, Matthew Calder

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Novel Ways to Generate Polypropionates for the Synthesis of Polyketide Natural Products by Matthew Edward Calder Doctor of Philosophy in Chemistry Stony Brook University 2012 Polyketide natural products are desirable targets due to their interesting biological and pharmacological properties. Polyketides contain synthetically challenging propionate subunits, which are comprised of alternating methyl and hydroxyl stereogenic centers. The synthesis of polypropionate subunits is the central theme of this work. The first project focused on employing the stereopentad and stereotetrad of the broad-spectrum antibiotic oleandomycin for the total synthesis of the polyketide natural product discodermolide. Our strategy involved a deconstruction/reconstruction process to access …

The Effects Of Habitat And Predation On Bay Scallop Populations In New York, John Michael Carroll

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Bay scallops once supported a vibrant fishery on Long Island. Populations crashed in the mid 1980s due to a series of brown tides, and while blooms haven't occurred within the Peconic Estuary since 1995, scallops have not naturally recovered. Concomitant with the loss of scallops due to the blooms was the disappearance of eelgrass, often called the "preferred" scallop habitat, possibly explaining the lack of recovery. Current restoration efforts have produced over 6 million scallops for deployment to the estuaries, leading to significant increases in the local scallop population. However, it is possible that the loss of seagrass might limit …

Expression And Function Of Rest In Oligodendrocyte Lineage Cells, Lisa Marie Dewald

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

The RE1-silencing transcription factor (REST) regulates the expression of neural specific genes by acting as a transcriptional repressor in non-neuronal cells. REST binds to repressor elements (RE1s) in the DNA and recruits histone deacetylases (HDACs) and other histone modifying and chromatin remodeling proteins through its corepressors mSin3 and CoREST. RE1s are located on a large number of genes that are required for the development and maintenance of the neuronal phenotype and are normally repressed in non-neural cells. By regulating gene expression, REST participates in the orderly developmental transition from a neuroepithelial precursor or stem cell to a functional neuron. Glial …

Examining The Ecological Role Of White Perch (Morone Americana) Using Acoustic Telemetry In The Great South Bay Estuary, New York., Martha Marie Divver

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Acoustic telemetry was used to investigate movement and behavior of the semi-anadromous white perch (Morone americana) in the Great South Bay system. Fifteen Vemco?? VR2 acoustic receivers were deployed in the Carmans River and another fifteen were placed in tributaries throughout the Bay. Forty fish were tagged with Vemco?? V9 acoustic transmitters from August 2010 - 2011, fifteen of which returned 28+ days of movement data. Spatial use of the River varied seasonally with an expanded range during autumn and spring and contracted range during summer and winter. Both residential and dispersive individuals existed within the population, suggesting connectivity between …

Automatic Mesh Generation And Processing For Biomedical Geometries, Volodymyr Dyedov

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Introduction of advantages of fluid dynamics simulations into clinical practice depends on ability to quickly create patient-specific computational models from computed tomography or magnetic resonance images with minimal human interaction. Our research addresses three steps in this process. First is identifying lung airways in radiological images. Our approach is based on a combination of geometric analysis of gradient vector flow and graph-based algorithms. Second is a novel method for robust and efficient computation of medial curves for complex biomedical geometries. This algorithm is based on three key concepts: a local orthogonal decomposition of geometry into substructures, a differential concept called …

Regulation Of Isg54-Mediated Apoptosis By Antioxidants Prdx5 And Sod2, Mel Pilar Espaillat

Stony Brook Theses and Dissertations Collection, 2006-2020 (closed to submissions)

Interferons (IFNs) are the most potent mediators of antiviral activities in the immune system. Viral molecular patterns are detected by receptors of the innate immune system, resulting in IFN production and subsequent IFN-stimulated gene (ISG) expression. The production of IFN serves as a danger signal that triggers a cascade of molecular events in the cell for the induction of antiviral mechanisms. The ISG products protect cells against viral replication, induce anti-proliferative mechanisms, and modulate the development of innate and adaptive immunity. The expression of ISG54 is mediated by type I IFN signaling and results in inducement of apoptosis via a …