Digital Commons Network^™

Staff Council Meeting, 2/21/2012, Unm Staff Council

UNM Staff Council

No abstract provided.

Fabrication And Performance Of A Microfluidic Traveling-Wave Electrophoresis System, K. D. Jo, J. E. Schiffbauer, Boyd F. Edwards, R. Lloyd Carroll, A. T. Timperman

All Physics Faculty Publications

A microfluidic traveling-wave electrophoresis (TWE) system is reported that uses a locally defined traveling electric field wave within a microfluidic channel to achieve band transport and separation. Low voltages, over a range of-0.5 to +0.5 V, are used to avoid electrolysis and other detrimental redox reactions while the short distance between electrodes, ∼25 μm, provides high electric fields of ∼200 V cm ^-1. It is expected that the low voltage requirements will simplify the future development of smaller portable devices. The TWE device uses four interdigitated electrode arrays: one interdigitated electrode array pair is on the top of the …

Curriculum Committee Course Proposals 02/21/12, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Polyamides Containing Amino Butyric Acid-Based Building Blocks, James K. Bashkin, Koeller J. Kevin, Terri G. Edwards, Christopher Fisher

UMSL Patents

The present invention relates to polyamide compositions and therapies for treating cells infected with papilloma virus.

For the most up-to-date information about these patents, including the availability of Certificates of Correction, be sure to check the United States Patent and Trademark Office's free, publicly accessible database: Patent Public Search https://ppubs.uspto.gov/pubwebapp/static/pages/landing.html

Stony Brook Press, V. 33, N. 09, Stony Brook University. Stony Brook Press.

Stony Brook Press

v. 33, n. 09, v.:ill. ; 38 cm (original analog pub.)

General Education Subcommittee Agenda, February 21, 2012, Utah State University

Educational Policies Committee

Course Approvals

Course Removals

Syllabi Approvals

Business

• Update on proposed USU 1370/3070
• Report on USU 1360 faculty meeting
• Review of Depth Courses

Other Business

Flyer News, Vol. 59, No. 29 (Feb. 21, 2012), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton.

Inactivation Of Androgen-Induced Regulator Ard1 Inhibits Androgen Receptor Acetylation And Prostate Tumorigenesis, Zehua Wang, Zemin Wang, Jianhui Guo, Yingchun Li, Jasmin H. Bavarva, Chiping Qian, M. Christiane Brahimi-Horn, Deyong Tan, Wanguo Liu

Faculty Publications

Androgen signaling through androgen receptor (AR) is critical for prostate tumorigenesis. Given that AR-mediated gene regulation is enhanced by AR coregulators, inactivation of those coregulators is emerging as a promising therapy for prostate cancer (PCa). Here, weshowthat the N-acetyltransferase arrest-defect 1 protein (ARD1) functions as a unique AR regulator in PCa cells. ARD1 is up-regulated in human PCa cell lines and primary tumor biopsies. The expression of ARD1 was augmented by treatment with synthetic androgen (R1881) unless AR is deficient or is inhibited by AR-specific siRNA or androgen inhibitor bicalutamide (Casodex). Depletion of ARD1 by shRNA suppressed PCa cell proliferation, …

De Novo Transcriptome Of Safflower And The Identification Of Putative Genes For Oleosin And The Biosynthesis Of Flavonoids, Haiyan Li, Yuanyuan Dong, Jing Yang, Xiuming Liu, Yanfang Wang, Na Yao, Lili Guan, Nan Wang, Jinyu Wu, Xiaokun Li

Physics Faculty Publications and Presentations

Safflower (Carthamus tinctorius L.) is one of the most extensively used oil crops in the world. However, little is known about how its compounds are synthesized at the genetic level. In this study, Solexa-based deep sequencing on seed, leaf and petal of safflower produced a de novo transcriptome consisting of 153,769 unigenes. We annotated 82,916 of the unigenes with gene annotation and assigned functional terms and specific pathways to a subset of them. Metabolic pathway analysis revealed that 23 unigenes were predicted to be responsible for the biosynthesis of flavonoids and 8 were characterized as seed-specific oleosins. In addition, a …

The Parthenon, February 21, 2012, Crystal Myers

The Parthenon

The Parthenon, Marshall University’s student newspaper, is published by students Monday through Friday during the regular semester and weekly Thursday during the summer. The editorial staff is responsible for the news and the editorial content.

The Current Volume 22 : Issue 21, Nova Southeastern University

Student Newspapers

No abstract provided.

The Myth Of Generic Pharmaceutical Competition Under The Hatch-Waxman Act, Emily Michiko Morris

Fordham Intellectual Property, Media and Entertainment Law Journal

Without a doubt, health care costs are on the rise, and how to reduce those costs is of great concern to many. The Hatch-Waxman Act attempts to reduce pharmaceutical costs by encouraging market entry by lower-priced generic pharmaceuticals and without a doubt has been successful in doing so over the last three decades. The question is, at what price? Although designed to balance greater generic market entry with stronger incentives for brand-name pharmaceutical innovators to continue developing new drugs, the Act appears to have fall short of making those incentives nearly strong enough and, indeed, likely weakens them. Perhaps more …

The Interaction Between An Omnivorous Mud Snail And Bloom-Forming Macroalgae Is Context-Dependent In Shallow Estuaries, Charles Yarrington

Theses

Eutrophication due to anthropogenic nutrient enrichment is the greatest factor leading to estuarine degradation. Even after external nutrient loading has been reduced, internal nutrient recycling has the potential to keep the system in a eutrophic state. In field studies, an association between the Eastern Mud Snail, Ilyanassa obsoleta (Say), and the opportunistic green macroalgae Ulva sp., has been observed and attributed to the detrital food source associated with the algal mat. In this study, we sought to determine the spatial and temporal context-dependence of this relationship, the reciprocal benefits of the association, and the potential feedbacks to macroalgal bloom formation …

Using Plant Canopy Temperature To Improve Irrigated Crop Management, Paul D. Colaizzi, Susan A. O'Shaughnessy, Steven R. Evett, Terry A. Howell

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Remotely sensed plant canopy temperature has long been recognized as having potential as a tool for irrigation management. However, a number of barriers have prevented its routine use in practice, such as the spatial and temporal resolution of remote sensing platforms, limitations in computing capacity and algorithm accuracy, and the cost and ruggedness of sensors and related components that can transmit and receive data wirelessly. Recent advances in all of these areas have made remote sensing more feasible in providing real-time feedback of field conditions. This can potentially reduce management time, maintain crop yield and crop water productivity, and detect …

A Putative P-Type Atpase Required For Virulence And Resistance To Haem Toxicity In Listeria Monocytogenes, Rosemary Rea, Roy D. Sleator, Et. Al.

Department of Biological Sciences Publications

Regulation of iron homeostasis in many pathogens is principally mediated by the ferric uptake regulator, Fur. Since acquisition of iron from the host is essential for the intracellular pathogen Listeria monocytogenes, we predicted the existence of Fur-regulated systems that support infection. We examined the contribution of nine Fur-regulated loci to the pathogenicity of L. monocytogenes in a murine model of infection. While mutating the majority of the genes failed to affect virulence, three mutants exhibited a significantly compromised virulence potential. Most striking was the role of the membrane protein we designate FrvA (Fur regulated virulence factor A; encoded by …

Lianas Have A Greater Competitive Effect Than Trees Of Similar Biomass On Tropical Canopy Trees, Michael F. Tobin, Alexandra Wright, Scott A. Mangan, Stefan A. Schnitzer

Biological Sciences Faculty Research and Publications

Lianas (woody vines) reduce growth and survival of host trees in both temperate and tropical forests; however, the relative strength of liana‐tree competition in comparison to tree‐tree competition remains unexplored. When controlling for biomass, lianas may have greater competitive effects than trees because the unique morphology of lianas allows them to reach the forest canopy at relatively small stem diameters and deploy a substantial crown above their host. We tested the hypothesis that lianas have a greater negative effect on canopy trees than do trees of similar biomass with a liana‐ and tree sapling‐cutting experiment in a seasonal tropical moist …

The George-Anne, Georgia Southern University

The George-Anne

• 'The Buried Life' Visits GSU
• Opinions
• Arts
• Classifieds
• Puzzles/ Comics
• Sports

The Mechanical Behavior Of Mutant K14-R125p Keratin Bundles And Networks In Neb-1 Keratinocytes, Daniel R. Beriault, Oualid Haddad, John V. Mccuaig, Zachary J. Robinson, David Russell, E. Birgitte Lane, Douglas S. Fudge

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Epidermolysis bullosa simplex (EBS) is an inherited skin-blistering disease that is caused by dominant mutations in the genes for keratin K5 or K14 proteins. While the link between keratin mutations and keratinocyte fragility in EBS patients is clear, the exact biophysical mechanisms underlying cell fragility are not known. In this study, we tested the hypotheses that mutant K14-R125P filaments and/or networks in human keratinocytes are mechanically defective in their response to large-scale deformations. We found that mutant filaments and networks exhibit no obvious defects when subjected to large uniaxial strains and have no negative effects on the ability of human …

Effects Of Vegetation, Corridor Width And Regional Land Use On Early Successional Birds On Powerline Corridors, Robert A. Askins, Corrine M. Folsom-O'Keefe, Margaret C. Hardy

Biology Faculty Publications

Powerline rights-of-way (ROWs) often provide habitat for early successional bird species that have suffered long-term population declines in eastern North America. To determine how the abundance of shrubland birds varies with habitat within ROW corridors and with land use patterns surrounding corridors, we ran Poisson regression models on data from 93 plots on ROWs and compared regression coefficients. We also determined nest success rates on a 1-km stretch of ROW. Seven species of shrubland birds were common in powerline corridors. However, the nest success rates for prairie warbler (Dendroica discolor) and field sparrow (Spizella pusilla) were

Division Of Undergraduate Education Proposal To The University Of Kentucky Faculty Senate Council: Establishing Policy And Guidelines For University Of Kentucky Dual Credit Partnerships With Secondary Schools, Randolph Hollingsworth

Undergraduate Education White Papers

This proposal was presented via handouts and accompanying slides to the University of Kentucky Faculty Senate Council on February 20, 2012. The proposal hinges on two main purposes:

1. an alternative for Kentucky's high school students that choose to accelerate their time to degree by completing a challenging course at UK; and,
2. a strategic improvement to existing enrollments at UK by high school students that would lead to more long-term relationships and shorten time to a college degree from UK.

The proposal includes definitions of terms commonly used, a few examples from UK benchmark institutions and an example lifecycle for the …

Gsu View, 2012-02-20, Office Of Marketing And Communications

GSU View

Newsletter published by Governors State University 2007-current.

Lanthorn, Vol. 46, No. 44, February 20, 2012, Grand Valley State University

Volume 46, July 14, 2011 - June 18, 2012

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

Spartan Daily February 20, 2012, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 138, Issue 12

Commonwealth Times 2012-02-20

Commonwealth Times, 1969-

No abstract provided.

February 20, 2012, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Columbia Chronicle (02/20/2012), Columbia College Chicago

Columbia Chronicle

Student newspaper from February 20, 2012 entitled The Columbia Chronicle. This issue is 44 pages and is listed as Volume 47, Number 21. Cover story: "City balancing act" Editor-in-Chief: Brianna Wellen

Independent Recruitment Of A Flavin-Dependent Monooxygenase For Safe Accumulation Of Sequestered Pyrrolizidine Alkaloids In Grasshoppers And Moths, Linzhu Wang, Till Beuerle, James Timbilla, Dietrich Ober

Publications and Research

Several insect lineages have developed diverse strategies to sequester toxic pyrrolizidine alkaloids from food-plants for their own defense. Here, we show that in two highly divergent insect taxa, the hemimetabolous grasshoppers and the holometabolous butterflies, an almost identical strategy evolved independently for safe accumulation of pyrrolizidine alkaloids. This strategy involves a pyrrolizidine alkaloid N-oxygenase that transfers the pyrrolizidine alkaloids to their respective N-oxide, enabling the insects to avoid high concentrations of toxic pyrrolizidine alkaloids in the hemolymph. We have identified a pyrrolizidine alkaloid N-oxygenase, which is a flavin-dependent monooxygenase, of the grasshopper Zonocerus variegatus. After heterologous expression in E. coli, …

February 20, 2012 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Daily Eastern News: February 20, 2012, Eastern Illinois University

February

No abstract provided.

Bmi-1 Absence Causes Premature Brain Degeneration, Guangliang Cao, Minxia Gu, Min Zhu, Junying Gao, Ying Yin, Charles Marshall, Ming Xiao, Jiong Ding, Dengshun Miao

Physical Therapy Faculty Publications

Bmi-1, a polycomb transcriptional repressor, is implicated in cell cycle regulation and cell senescence. Its absence results in generalized astrogliosis and epilepsy during the postnatal development, but the underlying mechanisms are poorly understood. Here, we demonstrate the occurrence of oxidative stress in the brain of four-week-old Bmi-1 null mice. The mice showed various hallmarks of neurodegeneration including synaptic loss, axonal demyelination, reactive gliosis and brain mitochondrial damage. Moreover, astroglial glutamate transporters and glutamine synthetase decreased in the Bmi-1 null hippocampus, which might contribute to the sporadic epileptic-like seizures in these mice. These results indicate that Bmi-1 is required for maintaining …