Digital Commons Network^™

Ipla2Β Overexpression In Smooth Muscle Exacerbates Angiotensin Ii-Induced Hypertension And Vascular Remodeling, Lindsay E Calderon, Shu Liu, Wen Su, Zhongwen Xie, Zhenheng Guo, Wanda Eberhard, Ming C. Gong

Physiology Faculty Publications

OBJECTIVES: Calcium independent group VIA phospholipase A₂ (iPLA₂β) is up-regulated in vascular smooth muscle cells in some diseases, but whether the up-regulated iPLA₂β affects vascular morphology and blood pressure is unknown. The current study addresses this question by evaluating the basal- and angiotensin II infusion-induced vascular remodeling and hypertension in smooth muscle specific iPLA₂β transgenic (iPLA₂β-Tg) mice.

METHOD AND RESULTS: Blood pressure was monitored by radiotelemetry and vascular remodeling was assessed by morphologic analysis. We found that the angiotensin II-induced increase in diastolic pressure was significantly higher in iPLA₂β-Tg …

The Collegian (2012-02-20), Rene Cardona Jr.

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 64, No. 21

Bjc Today

BJC Today

No abstract provided.

Overexpression Of Fatty Acid Amide Hydrolase Induces Early Flowering In Arabidopsis Thaliana, Neal D. Teaster, Jantana Keereetaweep, Aruna Kilaru, Yuh-Shuh Wang, Yuhong Tang, Christopher N.-Q. Tran, Brian G. Ayre, Kent D. Chapman, Elison B. Blancaflor

ETSU Faculty Works

N-Acylethanolamines (NAEs) are bioactive lipids derived from the hydrolysis of the membrane phospholipid N-acylphosphatidylethanolamine (NAPE). In animal systems this reaction is part of the “endocannabinoid” signaling pathway, which regulates a variety of physiological processes. The signaling function of NAE is terminated by fatty acid amide hydrolase (FAAH), which hydrolyzes NAE to ethanolamine and free fatty acid. Our previous work in Arabidopsis thaliana showed that overexpression of AtFAAH (At5g64440) lowered endogenous levels of NAEs in seeds, consistent with its role in NAE signal termination. Reduced NAE levels were accompanied by an accelerated growth phenotype, increased sensitivity to abscisic acid (ABA), enhanced …

Matrix Metalloproteinase Genes Are Transcriptionally Regulated By E2f Transcription Factors: A Link Between Cell Cycle Control And Metastatic Progression, Jacqueline Lea Johnson

USF Tampa Graduate Theses and Dissertations

The RbµE2F transcriptional regulatory pathway plays a critical role in the cell cycle. Rb is inactivated through multiple waves of phosphorylation, mediated mainly by cyclin D and cyclin E associated kinases. Once Rb is inactivated, cells can enter Sµphase. Collectively, three Rb family members and ten E2F proteins coordinate every additional stage of the cell cycle, from quiescence to mitosis. However the RbµE2F pathway is frequently altered in cancer. Aside from cell proliferation, the RbµE2F pathway regulates other essential cellular processes including apoptosis, cell differentiation, angiogenesis and DNA damage repair pathways, but its role in invasion and cancer progression is …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Dr. Lance McBrayer Allen E. Paulson College of Science and Technology

The Impact Of The Market Orientation Concept On Marketing Performance In The Libraries Of Jordanian Universities From The Point Of View Of Managers And Heads Of Departments, Fadel Jamil Klaib

Library Philosophy and Practice (e-journal)

This study aimed to investigate the impact of the application of the market orientation concept and its components on marketing performance in state and private university libraries in Jordan from the point of view of their managers and heads of departments. The initial study sample consisted of 170 library managers and heads of departments, of whom 95 (55.9 %) responded to the questionnaire.

The study revealed that both state and private university libraries in Jordan apply the concept of market orientation, although there are differences in the application of the components of market orientation. It also revealed that there are …

Development Of A Process For Identification Of The Operational Mode Of Industrial Sites Using High Dimensional Multi-Modal Data, Jake Clements

Theses

Many algorithms exist to determine the physical contents of an image. Target detection or anomaly detection algorithms, for example, use statistical and geometric approaches in high dimensional space to locate objects within a scene. Instead of target detection, however, it has become of interest of late to delve deeper into the field of remote sensing in order to perform textit{process detection}. Process detection refers to the ability to identify the operational mode of an industrial facility. To accurately complete this task will require a new set of analysis tools. This thesis discusses a method that can be used to perform …

Medical School Watercooler Newsletter - February 19, 2012, Lindsey Lyle

Watercooler Newsletter

This is the February 19, 2012 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• Med School Café - Expert Advice for the Community
• USA Researchers' Work Featured in American Society for Microbiology Journal of Virology
• Next Week's DSS - Dr. Alan Cherrington
• It's a Marathon, Not a Sprint
• 2012 Summer Research Proposal Deadline Approaching

Advertising And Consumerism In The Food Industry, Marlene Keller

Honors Theses - Providence Campus

The eating habits of society as a whole have drastically changed over the last few decades. The influx of technology, advertising, images in the media and changes within modern cultural and family values play a big role in the psychological evolution of consumers in the food service industry. My goal is to discover how the images in advertisements and media influence our desire to purchase food and alter our perception on what makes food appealing. In this thesis paper, I will start off with an introduction of how consumerism has changed since the use of advertisements first began. I will …

Daily Eastern News: January 18, 2012, Eastern Illinois University

January

No abstract provided.

Over My Dead Body: The Legal Nightmare And Medical Phenomenon Of Posthumous Conception Through Postmortem Sperm Retrieval, Devon D. Williams

Campbell Law Review

Part I of this Comment lays a historical foundation of the gradual development of case law dealing with reproductive rights as they relate to postmortem conception and discusses uniform laws that have partially addressed the issue of PMSR. Part II explains more specifically the difficulties facing the legal community due to the lack of precedent on the topic and lack of legislation; it also delves into the problems of construing postmortem intent and how that uncertainty affects PMSR from the outset. The first three subparts of Part III discuss the public policy arguments against PMSR, while the fourth subpart takes …

The Echo: February 17, 2012, Taylor University

2011-2012 (Volume 99)

Taylor welcomes 600 – Community growers – From Marion to the hill – Creation bill killed – Top 5 News Events of the Week – Fair trading at the bookstore – The contraceptive debate – RecycleMania (Feb 5-12) – The Bubble – Department Announcements – Athens on fire – London Olympics prepares to ward off sex trafficking – Around the World In 30 Seconds – Walk-a-Mile – Taylor University: Moshier’s next adventure – Take it to the Hoop – Classes you wish you could take – Single awareness day – Trend of the Week – Life & Times Love Words …

Ua12/2/1 College Heights Herald, Vol. 87, No. 23, Wku Student Affairs

WKU Administration Documents

WKU campus newspaper reporting campus, athletic and Bowling Green, Kentucky news.

• Koch, Cameron. Gatton Academy Receives $20,000 from AT&T
• Alleyne, Zirconia. Puppy Love – Tim Straubel
• Hayden, Natalie. WKU Watching Social Media Sites for Language – Censorship
• Spees, Monica. Roller Derby Members Are Some of WKU’s Own – Alexandra Brumley, Tucker Davis
• English, Molly. Q is for Queen – George Morgan, Crossdressing
• Hilbert, Hayley. WKU App Update Released
• Vogt, Darren. Editorial Cartoon re: Apartments vs. Dorms
• Williams, Joanna. To Dorm or Not to Dorm
• West, Natalie. Store Personalizing Products for WKU Greeks
• Harrison, Taylor. Locks of Love Event to Be …

The Tiger Vol. 106 Issue 5 2012-02-17, Clemson University

Tiger Newspapers

No abstract provided.

Reporter - February 17th 2012, Rit Reporter Staff

University Publications

No abstract provided.

Halocarbocyclization Entry Into The Oxabicyclo[4.3.1]Decyl Exomethylene-Δ-Lactone Cores Of Linearifolin And Zaluzanin A - Exploiting Combinatorial Catalysis, Sandeep K. Ginotra, Jacob A. Friest, David B. Berkowitz

David Berkowitz Publications

A streamlined entry into the sesquiterpene lactones (SQL) cores of linearifolin and zaluzanin A is described. Stereochemistry is controlled through transformations uncovered by ISES (In-Situ- Enzymatic-Screening). Absolute stereochemistry derives from kinetic resolution of 5- benzyloxypentene-1,2-oxide, utilizing a β-pinene-derived-Co(III)-salen. Relative stereochemistry (1,3-cis-fusion)is set via formal halometalation/carbocyclization, mediated by [Rh(O₂CC₃F₇)₂]₂/ LiBr. Subsequent ring-closing metathesis (RCM-Grubbs II) yields the title exomethylene-δ- lactone SQL-cores. In complementary fashion, RCM with Grubbs-I catalyst provides the oxabicyclo[3.3.1]nonyl-core of xerophilusin R and zinagrandinolide.

The Utah Statesman, February 17, 2012, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Daily Gamecock, Friday, February 17, 2012, University Of South Carolina, Office Of Student Media

February

No abstract provided.

Volume Cxxix, Number 15, February 17, 2012, Lawrence University

The Lawrentian

No abstract provided.

Daily Eastern News: January 17, 2012, Eastern Illinois University

January

No abstract provided.

Sendai Virus-Based Liposomes Enable Targeted Cytosolic Delivery Of Nanoparticles In Brain Tumor-Derived Cells, Veronica Dudu, Veronica Rotari, Maribel Vazquez

Publications and Research

BACKGROUND: Nanotechnology-based bioassays that detect the presence and/or absence of a combination of cell markers are increasingly used to identify stem or progenitor cells, assess cell heterogeneity, and evaluate tumor malignancy and/or chemoresistance. Delivery methods that enable nanoparticles to rapidly detect emerging, intracellular markers within cell clusters of biopsies will greatly aid in tumor characterization, analysis of functional state and development of treatment regimens.

RESULTS: Experiments utilized the Sendai virus to achieve in vitro, cytosolic delivery of Quantum dots in cells cultured from Human brain tumors. Using fluorescence microscopy and Transmission Electron Microscopy, in vitro experiments illustrated that these virus-based …

Uab Students Mingle With World's Best Immunologists, Tyler Greer

Browse All News

No abstract provided.

Chancellor's Report 2012-02, John Pugh

Chancellor's Report

No abstract provided.

Illinois State University Board Of Trustees Meeting Materials, February 17, 2012, Board Of Trustees

Illinois State University Board of Trustees (1995-2013)

Minutes, reports, and action items relating to the February 17, 2012 meeting of the Illinois State University Board of Trustees.

Coupling Of Fog And Marine Microbial Content In The Near-Shore Coastal Environment, M. E. Ducker, Gregory D. O'Mullan, K. C. Weathers, A. R. Juhl, M. Uriarte

Publications and Research

Microbes in the atmosphere (microbial aerosols) play an important role in climate and provide an ecological and biogeochemical connection between oceanic, atmospheric, and terrestrial environments. However, the sources and environmental factors controlling the concentration, diversity, transport, and viability of microbial aerosols are poorly understood. This study examined culturable microbial aerosols from a coastal environment in Maine (USA) and determined the effect of onshore wind speed and fog presence on deposition rate, source, and community composition. During fog events with low onshore winds (

Taming Twombly: An Update After Matrixx, Edward A. Hartnett

Law and Contemporary Problems

No abstract provided.

A Placebo-Controlled, Double-Blind, Dose-Escalation Study To Assess The Safety, Tolerability And Pharmacokinetics/Pharmacodynamics Of Single And Multiple Intravenous Infusions Of Azd9773 In Patients With Severe Sepsis And Septic Shock, Peter E. Morris, Brian Zeno, Andrew C. Bernard, Xiangning Huang, Shampa Das, Timi Edeki, Steven G. Simonson, Gordon R. Bernard

Surgery Faculty Publications

INTRODUCTION: Tumor necrosis factor-alpha (TNF-α), an early mediator in the systemic inflammatory response to infection, is a potential therapeutic target in sepsis. The primary objective of this study was to determine the safety and tolerability of AZD9773, an ovine, polyclonal, anti-human TNF-α Fab preparation, in patients with severe sepsis. Secondary outcomes related to pharmacokinetic (PK) and pharmacodynamic (PD) parameters.

METHODS: In this double-blind, placebo-controlled, multicenter Phase IIa study, patients were sequentially enrolled into five escalating-dose cohorts (single doses of 50 or 250 units/kg; multiple doses of 250 units/kg loading and 50 units/kg maintenance, 500 units/kg loading and 100 units/kg maintenance, …

Homeopoesis: Aristotle On Nutrition And Growth, John Thorp

The Society for Ancient Greek Philosophy Newsletter

This paper seeks to understand how Aristotle’s ideas about nutrition avoid cancerous growth: why does the flesh that is distilled out of the digestive process, and that travels out to the various parts of the body, not just produce formless growth? De Anima II.5 gives a purely formal reply ("limit and ratio:") Using GA and GC I try to put together Aristotle's schematic account of the process.

Integrating Advanced Writing Content Into A Scholarly Inquiry In Nursing Course, Barbara L. Madleco

Faculty Publications

Since there are few data examining methods to help students learn to write in a scholarly manner, the purposes of this project were to (1) evaluate students’ learning of writing content integrated into a Scholarly Inquiry in Nursing course by examining differences in scores on a writing assessment taken at the beginning and end of the course; and (2) examine student confidence ratings relative to writing to see if it improved during the course. After obtaining IRB approval and informed consent, the CLIPS pre and post assessment mean scores of 82 students in a Scholarly Inquiry in Nursing course were …