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The Truth Between The Teeth: An Analysis Of Interproximal Tooth Wear At The Ables Creek Cemetery, Amy Reynolds Warren

Graduate Theses and Dissertations

Current archaeological knowledge suggests that, by the Late Mississippian period, inhabitants of the southeastern United States had adopted maize agriculture and that maize was a key component of the normal diet. However, in some regions where wild food resources were easily attainable, there is evidence that the transition to agriculture was delayed or did not occur at all. This thesis examines Late Mississippian skeletal collections from two sites in eastern Arkansas, Ables Creek and Upper Nodena. Analysis of differences in interproximal tooth wear facet size and caries rates between the two populations reveals that the diets at these roughly contemporary …

You Can Breastfeed But . . . : A Rhetorical Analysis Of Images And Commentary On Breastfeeding, Jonna Ziniel

Dissertations

This dissertation is a study of breastfeeding images and the commentary about those images, from a rhetorical perspective. Specifically, I use a feminist lens in order to analyze images of breastfeeding in both magazine and online environments, as well as online commentary about the images. I examine both celebrity and non-celebrity images of breastfeeding from popular pregnancy and parenting magazines, non-traditional parenting magazines, company web sites, and online articles and blog sites. Chapter one presents a statement of purpose, research questions, and an examination of the current literature pertinent to the study including sections on breastfeeding benefits, the sexualized woman's …

Signaling Pathways And Genetic Interactions That Lead To Metastatic Cancer In Drosophila Melanogaster, Amanda Cole

Renée Crown University Honors Thesis Projects - All

Cancer is a complex and multigenic disease, which is typically initiated by genetic mutations in tumor suppressor genes that regulate homeostatic mechanisms within cells. Oncogenic promoter mutations, like those involved in signal transduction pathways, also have the potential to induce cancer in an otherwise healthy organism. Transformation is highly dependent upon mutations to both tumor suppressor and oncogenes, as neither mutation is exclusive in its ability to generate malignant tumors. In the model organism, Drosophila melanogaster, I have generated metastatic cancer through the genetic effect of overactive Raf signaling, in conjugation with silencing selected tumor suppressor genes using RNA …

The Liminality Of Zimmedari And Its Consequences On The Water Quality And Health Of Meena Communities In Rajasthan, Firdaus Arastu

Renée Crown University Honors Thesis Projects - All

Water is an essential need for people everywhere, yet its security is increasingly becoming endangered around the world. The escalating global water crisis has profound ramifications for health and livelihood particularly in developing countries like India. India faces enormous development challenges in addressing the needs of a rapidly growing population. The world’s largest democracy, India needs to improve its delivery of public services, especially to the poor and those living in rural areas.

The present study investigates the current public health situation in Rajasthan and the challenges India faces in providing water and health services. Fieldwork was conducted in rural …

Genomic Analysis Of Immune Response Against Vibrio Cholerae Hemolysin In Caenorhabditis Elegans, Surasri N. Sahu, Jada Lewis, Isha Patel, Serdar Bozdag, Jeong H. Lee, Joseph E. Leclerc, Hediye Nese Cinar

Mathematics, Statistics and Computer Science Faculty Research and Publications

Vibrio cholerae cytolysin (VCC) is among the accessory V. cholerae virulence factors that may contribute to disease pathogenesis in humans. VCC, encoded by hlyA gene, belongs to the most common class of bacterial toxins, known as poreforming toxins (PFTs). V. cholerae infects and kills Caenorhabditis elegans via cholerae toxin independent manner. VCC is required for the lethality, growth retardation and intestinal cell vacuolation during the infection. However, little is known about the host gene expression responses against VCC. To address this question we performed a microarray study in C. elegans exposed to V. cholerae strains with intact and deleted hlyA …

Rethinking The Industrial Landscape - Revealing The Curative Potential Of Genetically Modified Plants, Susannah Horton

All Theses

At the turn of the 21st century, much like the turn of the 20th century there has been a major shift in North America with its industries and their impact on the landscape. With a trend of massive deindustrialization of large-scale production facilities throughout the (Gibbs 2003, 222-236) United States, it has directly impacted the landscape. There are currently changes underway in the American industrial landscape emphasizing a new technology whereby pharmaceuticals are manufactured in recombinant plants. These plant-derived pharmaceuticals are poised to become the next major part of the pharmaceutical industry. By recognizing the potential and studying the possible …

Effects Of Temperature On Emergence And Seasonality Of West Nile Virus In California, David M. Hartley, Christopher M. Barker, Arnaud Le Menach, Tianchan Niu, Holly Gaff, William K. Reisen

Biological Sciences Faculty Publications

Temperature has played a critical role in the spatiotemporal dynamics of West Nile virus transmission throughout California from its introduction in 2003 through establishment by 2009. We compared two novel mechanistic measures of transmission risk, the temperature-dependent ratio of virus extrinsic incubation period to the mosquito gonotrophic period (BT), and the fundamental reproductive ratio (R₀) based on a mathematical model, to analyze spatiotemporal patterns of receptivity to viral amplification. Maps of BT and R₀ were created at 20-km scale and compared throughout California to seroconversions in sentinel chicken flocks at half-month intervals. Overall, estimates of BT and …

Faculty And Staff Perceptions Of Sustainability Initiatives On Three Arkansas Two-Year College Campuses, Kenneth Ray Warden Iii

Graduate Theses and Dissertations

The purpose of this quantitative study was to explore higher education faculty and staff perspectives on sustainability initiatives within their respective institutions. Subjects of this study were faculty and staff members from three rural two year institutions of higher education in Arkansas. Data was gathered using an electronically delivered survey instrument. The survey organized sustainability initiatives into three categories which are management, academic, and operations. The organization of the survey was based upon the National Wildlife Federation's study, Campus Environment 2008; A National Report Card on Sustainability in Higher Education. In effort to determine the relationship if any between the …

Role Of Lactic Acid Bacteria As A Bio-Sanitizer To Prevent Attachment Of Listeria Monocytogenes On Deli Slicer Contact Surfaces, And The Influence Of Listeria Innocua On The Attachment Of L. Monocytogenes On Selected Materials Located In The Food-Processing Environment, Jean Baptiste Ndahetuye

Graduate Theses and Dissertations

Listeria monocytogenes an important foodborne pathogen that continues to be a serious problem for the food industry. This pathogen contaminates food primarily during post-harvest in the food-processing environment. Its ecology in the food-processing environment is not well understood but previous research has demonstrated the ability of L. monocytogenes to survive on food contact surfaces after cleaning and disinfection. The current study explored the attachment of three lactic acid bacteria (LAB) strains, Lactobacillus animalis , Lb. amylovorus and Pediococcus acidilactici , their combination in a cocktail, and their influence to prevent the attachment of L. monocytogenes at room temperature by examining …

Aptamer-Based Spr Biosensor For Detection Of Avian Influenza Virus, Hua Bai

Graduate Theses and Dissertations

Rapid and specific detection of avian influenza (AI) virus is urgently needed with the concerns over the outbreaks of highly pathogenic H5N1 avian influenza in animal and human infection. Aptamers are artificial oligonucleic acid that can specifically bind to target molecules. They show comparable affinity for target virus and better thermal stability than monoclonal antibodies. Those advantages make aptamers promising candidates in diagnostic and detection applications. The goal of this research was to use DNA&ndashaptamer as the specific recognition element in a portable surface plasmon resonance (SPR) biosensor for detection of AI H5N1 virus in poultry.

A SPR biosensor was …

Pronthocyanidin-Rich Cranberry-Fractioninduced Alteration Of Periodontal Pathogen Lipopolysaccharide Functions, Vreiti Sangha

Theses and Dissertations (ETD)

The cranberry (species: Vaccinium macrocarpon, family: Ericaceae) is a polyphenolicrich berry fruit native to North America and exhibits numerous beneficial properties for human health, such as inhibition of human cancer cell line proliferation and prevention of urinary tract colonization by bacterial pathogens. The proanthocyanidin rich cranberry fraction has long been speculated to possess the capacity to reduce the production of inflammatory mediators by LPSstimulated macrophages and gingival fibroblasts and to inhibit host extracellular matrix destructive enzyme production and activity.

The purpose of this investigation was to examine the effect of cranberry non dialyzable material (NDM), which was shown to be …

Variables Associated With Critical Illness Among Clark County Residence Hospitalized With H1n1 Influenza A Virus During The 2009 Influenza Season., Jonathan P. Hyatt

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background:In 2009, a novel H1N1 Influenza A virus was detected in the population. Because it can potentially affect a different population than the influenza strains circulating for the past 35 years, it is critical for physicians, practitioners and public health organizations to understand who is susceptible to this disease, and which sub-populations are most likely to suffer critical illness. The objective of this study was to examine the factors unique to 2009 H1N1 infection, with the goal of finding the variables associated with ICU admission (Critical Illness) in the Clark County 2009 H1N1 patient.

Methods:Factors that were assessed in this …

Modeling The Effects Of Substance Dependence On General Self-Reported Health Using Nominal Regression, Taylor Moseley

UNLV Theses, Dissertations, Professional Papers, and Capstones

The goal of this research project was to produce a model of the effects of drug dependence on general self-rated health. Due to power issues, two additional models, one for cocaine and one for heroin, were required. The models used data from the 2005-2009 National Survey on Drug Use and Health. The result of this effort was a ranking of the effects of drug dependence on general health for individuals and for the study population. The model controlled for infectious, chronic and mental illness as well as sociodemographic variables. Significantly increased odds ratios were found for alcohol, marijuana, analgesics, and …

Clinical Practice Guidelines For Primary Care Providers' Evaluation Of Patient Fitness To Fly, Kerry Colleen Palakanis

UNLV Theses, Dissertations, Professional Papers, and Capstones

Commercial air travel is amongst the safest forms of transportation yet the environment within the aircraft cabin to which the passenger is exposed may have adverse physiological and psychological effects on passengers, especially for those with pre-existing medical issues. A comprehensive, systematic review and analysis of current literature was performed to develop evidenced-based guidelines for evaluation of passenger fitness to fly for integration into primary care practice. Recommendations from the most current fitness to fly guidelines and disease-specific published research related to in-flight medical issues were evaluated and the Grades of Recommendation Assessment, Development and Evaluation (GRADE) method was utilized …

Motivating Men Who Have Sex With Men To Get Tested For Hiv, Magaly M. Blas, Luis A. Menacho, Isaac E. Alva, E. Roberto Orellana

School of Social Work Faculty Publications and Presentations

Although men who have sex with men (MSM) have the highest HIV prevalence in Peru, they are underserved by traditional preventive programs. Interestingly, in Peru the Internet and cell-phones have emerged as a convenient tool to reach this population.

Therapist Characteristics Influencing Physical Therapy Non-Treatment In The Acute Care Setting, Daniel Mcgarvey, Colby Olsen, Aaron Van Wagoner

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background and Purpose: Research has found that participation in physical therapy (PT) services in the acute care setting increases functional outcomes and decreases patient length of stay. Certain physical therapist characteristics could be a potential source of influence on patient non-participation in physical therapy in the acute care setting. The purpose of this study was to determine whether specific characteristics of therapists and patients are predictive of physical therapy non-treatment.

Subjects: Subjects included 16 physical therapists or physical therapist assistants and 1225 patients at a community acute care hospital.

Methods: Characteristics of each therapist and their corresponding patient data were …

Exitus: An Agent-Based Evacuation Simulation Model For Heterogeneous Populations, Matthew T. Manley

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Evacuation planning is important for businesses given the continuing occurrence of both natural and human-caused disasters throughout the world. Unfortunately, the traditional fire-drill approach is impractical for many large organizations but especially those responsible for airports and sports arenas. The purpose of this research was to develop a new computer program capable of simulating large scale evacuations in such buildings. The program, called Exitus, is different from other evacuation simulators in the way it considers the physical, psychological, and social characteristics of individuals with disabilities during emergency situations.

In this research, Exitus was used to simulate evacuations of three buildings …

Global Food Security: In Our National Interest, David P. Lambert

Journal of Food Law & Policy

All Americans have a direct stake in the problem of global hunger, which has many dimensions. For most of us it is a profound moral issue, and we are guided by our faith to respond.

Adolescent Steroid Use : A Logistic Regression Analysis., Anthony Gennaro Vito 1987-

Electronic Theses and Dissertations

This study compared the criminological theories of peer association and low self-control and its effect on adolescent steroid use. The data for this study comes from the 12th grade survey of the 2009 Monitoring the Future Project Form 6. The purpose of the Monitoring the Future Project (MTF) is to understand changes in values, behaviors, and lifestyle orientations of the American youth. The study found that peer association, low self-control and the sex of the adolescent are all significant predictors of adolescent steroid use.

Parasitic Nematodes In Humans : Exploring The Host-Parasite Dynamic Through Historical, Biological, And Public Health Evaluations Of Infection., Erin Christine Welsh 1987-

Electronic Theses and Dissertations

This thesis investigated infection dynamics of parasitic nematodes at both the population and individual levels by exploring evolutionary and historical aspects of infection as well as how host-parasite interactions influence virulence. In particular, this thesis sought to answer questions of how host populations have influenced the spread of infection and how transmission determines infection virulence, with a final goal of understanding how eradication programs for parasites can be developed or improved with this knowledge. The host-parasite dynamic was explored throughout history, with particular focus on the ways host populations have shaped infection distribution in present, historic, and prehistoric times. Then, …

Antibody-Mediated Protection Against Pulmonary Infection With Virulent Type A Francisella Tularensis, Gopi Mara-Koosham

Biomedical Sciences ETDs

Respiratory infections with the virulent type A strains of Francisella tularensis (Ft) cause pneumonic tularemia, an illness which results in high case fatalities in the absence of timely antibiotic treatment. Although immunization is an effective countermeasure, vaccines against pulmonary tularemia are currently unavailable. A better understanding of protective immune components is therefore needed to develop licensable vaccines against pulmonary tularemia. While the indispensability of cell-mediated immunity in protection against this gram-negative intracellular bacterium is well-documented, the protective role of antibodies (Abs) is unclear. Hence we examined the role of humoral immunity by developing a passive immunization model of respiratory tularemia …

Cell-Mediated Immunity In Porcine Reproductive And Respiratory Syndrome Virus, Rajeshwari Parida

School of Veterinary and Biomedical Sciences: Dissertations, Theses, and Student Research

Porcine reproductive and respiratory syndrome virus is a significant swine pathogen which exhibits considerable sequence diversity. In an attempt to identify highly conserved T-cell epitopes contained in proteins of this virus, we examined heptadecamer peptides spanning the sequence of the PRRSV nonstructural proteins 9, 10 and 11, all of them are highly conserved, for their ability to elicit a recall proliferative and interferon-gamma response in peripheral blood mononuclear cells obtained from pigs immunized against the type-II PRRSV strain FL-12. These studies led to the identification of seven peptides, two from each NSP 9 and NSP 10 and, three from NSP …

Acetaldehyde And Epithelial Junctions: Role Of Pp2a And Occludin Phosphorylation, Mitzi Dunagan

Theses and Dissertations (ETD)

Chronic alcohol consumption causes health problems including cancers, liver damage, and cirrhosis.These problems are exacerbated by endotoxins from the bacterial population of the colon, which can enter the bloodstream when gastrointestinal tight junctions, protein complexes that prevent paracellular passage of molecules, are compromised. The mechanisms of this barrier disruption are the subject of current study.

Acetaldehyde, produced as a result of ethanol breakdown by intestinal microflora as well as intestinal epithelia, is a known carcinogen. It compromises the barrier function of intestinal epithelial cells by causing irregularities in the phosphorylation of tight junction proteins. It also reacts with proteins, lipids, …

The Molecular Basis Of Fitness And Transmissibility Of Neuraminidase Inhibitor Resistant Influenza A Viruses, Susu Duan

Theses and Dissertations (ETD)

Neuraminidase (NA) inhibitors including oral oseltamivir and inhaled zanamivir are among the first line of defense against influenza virus infection. Development of resistance to NA inhibitors is a huge drawback for limited options for the control of influenza. During the first decade of NA inhibitor use, the detection rates of resistance to both NA inhibitors had remained low in circulating influenza viruses. However, the 2008~2009 season was marked by a radical increase of prevalence of oseltamvir resistance from <1% to >90% in worldwide surveillance in less than a year. The resistance was solely linked to NA H275Y variants of seasonal H1N1 viruses, …

Effects Of Thymus Size And Involution On The Contribution Of Recent Thymic Emigrants To The Peripheral T Cell Pool, Michelle L. Bolner

Dissertations and Theses (Open Access)

The contribution of recent thymic emigrants (RTEs) to the peripheral naïve T cell population is necessary to maintain diversity of the T cell receptor (TCR) repertoire and produce immune responses against newly encountered antigens.

The thymus involutes with age, after irradiation or chemotherapy, and due to severe viral infections. Thymus involution results in decreased thymopoiesis and RTE output leading to a reduced diversity of peripheral T cells. This increases susceptibility to disease and impairs immune responsiveness to vaccines. Therefore, studies aimed at maintaining or regenerating thymic function are integral for maintaining and restoring peripheral TCR diversity.

Mice that express a …

Evidence Of Human Endogenous Retrovirus K Involvement In Human Cancer, Joshua B. Plummer

Dissertations and Theses (Open Access)

Many lines of clinical and experimental evidence indicate a viral role in carcinogenesis (1-6). Our access to patient plasma, serum, and tissue samples from invasive breast cancer (N=19), ductal carcinoma

in situ (N=13), malignant ovarian cancer (N=12), and benign ovarian tumors (N=9), via IRB-approved and informed consent protocols through M.D. Anderson Cancer Center, as well as normal donor plasmas purchased from Gulf Coast Regional Blood Center (N=6), has allowed us to survey primary patient blood and tissue samples, healthy donor blood from the general population, as well as commercially available human cell lines for the presence of human endogenous retrovirus …

Assessing African National Adaptation Programmes Of Action: Giving A Voice To The Voiceless, Natalia Valenzuela-Cevallos

All Theses

ABSTRACT
The earth continues to experience climate change. Although it is occurring worldwide, the Least Developed Countries (LDCs) are particularly in danger from various adverse consequences due to their low adaptive capability. In order to assist LDCs prepare for climate change, the United Nations (UN) established the National Adaptation Programmes of Action (NAPAs). Part of the rationale behind the creation of the NAPAs was to help LDCs prepare for climate change effects, while protecting the poor and using sound environmental management. To date, 47 LDCs have submitted NAPAs to the UN, from which 32 are African LDCs.
Prior to this …

Quantitative Workload, Physical Activity, And Quality Of Sleep: An Investigation Of Nurses Working The Night Shift And 10 Hour Or Longer Shifts, Kyle Stanyar

All Theses

Approximately 30% to 40% of adults suffer from some form of insomnia in any given year. Insomnia-related productivity losses for organizations are estimated at $5 billion dollars annually. Long work weeks, shift work, and high workload have been linked to poor sleep quality. Currently, there is a gap in research on how physical activity affects quality of sleep among nurses who work long hours and nurses who work the night shift. Therefore two samples of nurses were examined; nurses who work 10 hour or longer shifts (N = 222) and nurses who work the night shift (N = 97). This …

The Effect Of Cockpit Noise On The Temporary Threshold Shift Of Cessna 172sp Flight Instructors, Andrew Robert Bellini

Doctoral Dissertations and Master's Theses

The purpose of this thesis was to study the temporary threshold shift of general aviation flight instructors resulting from their working environment. Exposure to noise before a temporary threshold shift completely recovers can cause a permanent threshold shift with no possibility of recovery, resulting in permanent hearing loss. A result showing minimal to no temporary threshold shift would indicate that hearing personal protective equipment is working properly. This study used sound-level measurements, and audiometric testing, together with survey data to determine whether or not flight instructors were at risk for potential hearing impairment due to temporary threshold shift. Independent t …

International Adoption And Language Development, Stacy L. Nelson

Research Papers

No abstract provided.