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Demam Berdarah Dengue Di Perdesaan, Erna Kusumawardani, Umar Fahmi Achmadi

Kesmas

Berbeda dengan beberapa negara, laporan kejadian kasus demam berdarah dengue (DBD) di perdesaan Indonesia belum banyak dilaporkan. Penelitian ini bertujuan untuk memberikan gambaran kejadian DBD di perdesaan di wilayah perbatasan Kabupaten Bogor dan Kabupaten Lebak, Jawa Barat. Penelitian ini menggunakan desain studi kasus seri dengan sampel seluruh penderita DBD yang tercatat di puskesmas pada periode bulan Januari 2011 sampai April 2012. Hasil penelitian menemukan 18 kasus DBD dan 4 kasus kematian (case fatality rate, CFR = 22%). Sebagian besar kasus berjenis kelamin laki-laki (58,3%), berusia > 15 tahun (58,3%), tidak bekerja/ibu rumah tangga (50%), melakukan mobilitas (66,7%), mempunyai pengetahuan yang baik …

A Case Of A Male With Fever And Fatigue, Steve Ting

The Medicine Forum

This is a case of a 78 year old Caucasian gentleman who presented to the hospital in the early summer with complaints of high fevers and progressive fatigue. The patient lives near Philadelphia and enjoys doing yard work. He reported finding a tick attached to the skin near his groin approximately 3 weeks prior to admission. The tick was removed; however the patient was unsure of the duration of the tick attachment. He also denied developing any significant rash in that area. He had no recent sick contacts and no recent history of travel. He began developing fever spikes up …

Nonspecific Interstitial Pneumonitis In Hiv-Infected Patients, Bobbak Vahid

The Medicine Forum

A 24 year old African-American male with a history of AIDS with a recent CD4 count of 57/uL, is admitted to the hospital with substernal chest pain and shortness of breath for the past two weeks. Dyspnea is mostly on exertion, and the patient denied productive cough or hemoptysis, fevers, chills, or night sweats. Three weeks prior to presentation, the patient underwent esophagogastroduodenoscopy, which revealed an esophageal ulcer. Biopsies did not show any specific pathology and cultures were negative. Outpatient medications include prednisone, rabeprazole, fluconazole, clarithromycin, and ethambutol, bactrim.

Vitals on admission were as follows: temperature 97.2, pulse 80/min, and …

Materials And Methods For Prevention And Treatment Of Rna Viral Diseases, Shyam S. Mohapatra, Aruna K. Behera

USF Patents

The subject invention concerns a method of inhibiting an RNA virus infection within a patient by increasing the amount of 2-5 oligoadenylate synthetase (2-5 AS) activity within the patient. Preferably, the preventative and therapeutic methods of the present invention involve administering a nucleotide encoding 2-5 AS, or at least one catalytically active fragment thereof, such as the p40, p69, p100 subunits, to a patient in need thereof. The present inventors have determined that overexpression of 2-5AS causes a reduction in epithelial cell damage, reduction in infiltration of mononuclear cells in the peribronchiolar and perivascular regions, and reduction in thickening of …

Chronic Care And Prevention: Evolution In Practice And Finance, John V. Jacobi

Marquette Elder's Advisor

No abstract provided.

Prevention Paradigms, Over-Diagnosis And Treatment, And Mad Men, Alison Barnes

Marquette Elder's Advisor

No abstract provided.

Is Bioethics The Engine Of Research?, Edgard Nehmé Prof.

International Arab Journal of Dentistry

«Do not try to become a man of successbut rather a man of value».Albert Einstein

Gene Expression Analysis Of A Murine Model With Pulmonary Vascular Remodeling Compared To End-Stage Ipah Lungs, Kayoko Shimodaira, Yoichiro Okubo, Eri Ochiai, Haruo Nakayama, Harutaka Katano, Megumi Wakayama, Minoru Shinozaki, Takao Ishiwatari, Daisuke Sasai, Naobumi Tochigi, Tetsuo Nemoto, Tsutomu Saji, Katsuhiko Kamei, Kazutoshi Shibuya

Microbiology, Immunology, and Molecular Genetics Faculty Publications

BACKGROUND: Idiopathic pulmonary arterial hypertension (IPAH) continues to be one of the most serious intractable diseases that might start with activation of several triggers representing the genetic susceptibility of a patient. To elucidate what essentially contributes to the onset and progression of IPAH, we investigated factors playing an important role in IPAH by searching discrepant or controversial expression patterns between our murine model and those previously published for human IPAH. We employed the mouse model, which induced muscularization of pulmonary artery leading to hypertension by repeated intratracheal injection of Stachybotrys chartarum, a member of nonpathogenic and ubiquitous fungus in our …

Research Team Sets Sights On New Era In Neuroprotection, Greg Williams

Browse All News

No abstract provided.

Using Microbial Source Tracking Techniques To Identify Fecal Indicator Bacteria In The Horse Creek Watershed In Aiken, Sc, Pamela W. Steen, Paul Thomas, S Michele Harmon

S.C. Water Resources Conference

2012 S.C. Water Resources Conference - Exploring Opportunities for Collaborative Water Research, Policy and Management

Borrowing Information Across Populations In Estimating Positive And Negative Predictive Values, Ying Huang, Youyi Fong, John Wei, Ziding Feng

UW Biostatistics Working Paper Series

A marker's capacity to predict risk of a disease depends on disease prevalence in the target population and its classification accuracy, i.e. its ability to discriminate diseased subjects from non-diseased subjects. The latter is often considered an intrinsic property of the marker; it is independent of disease prevalence and hence more likely to be similar across populations than risk prediction measures. In this paper, we are interested in evaluating the population-specific performance of a risk prediction marker in terms of positive predictive value (PPV) and negative predictive value (NPV) at given thresholds, when samples are available from the target population …

Activation Of Amp-Activated Protein Kinase By 3,39-Diindolylmethane (Dim) Is Associated With Human Prostate Cancer Cell Death In Vitro And In Vivo, Di Chen, Sanjeev Banerjee, Qiuzhi C. Cui, Dejuan Kong, Fazlul H. Sarkar, Q. Ping Dou

Oncology Faculty Publications

There is a large body of scientific evidence suggesting that 3,39-Diindolylmethane (DIM), a compound derived from the digestion of indole-3-carbinol, which is abundant in cruciferous vegetables, harbors anti-tumor activity in vitro and in vivo. Accumulating evidence suggests that AMP-activated protein kinase (AMPK) plays an essential role in cellular energy homeostasis and tumor development and that targeting AMPK may be a promising therapeutic option for cancer treatment in the clinic. We previously reported that a formulated DIM (BR-DIM; hereafter referred as B-DIM) with higher bioavailability was able to induce apoptosis and inhibit cell growth, angiogenesis, and invasion of prostate cancer cells. …

A Preliminary Qualitative Evaluation Of The Virginia Gold Quality Improvement Program, Gerald A. Craver, Amy K. Burkett

The Qualitative Report

Certified nursing assistants (CNAs) perform an important role in the long-term care system because they provide the majority of paid care to nursing facility residents. Unfortunately, annual CNA turnover often exceeds 100 percent nationally. Many factors account for this, including stressful working conditions, low pay, and limited benefits. The end result of high turnover is compromised continuity of care for residents, which often leads to poor quality and substandard care. In an effort to improve quality of care and staffing, the Virginia Department of Medical Assistance Services in 2009 implemented a pilot program, known as the Virginia Gold Quality Improvement …

Influenza-Infected Neutrophils Within The Infected Lungs Act As Antigen Presenting Cells For Anti-Viral Cd8+ T Cells, Matthew M. Hufford, Graham Richardson, Haixia Zhou, Balaji Manicassamy, Adolfo Garcia-Sastre, Richard I. Enelow, Thomas J. Braciale

Dartmouth Scholarship

Influenza A virus (IAV) is a leading cause of respiratory tract disease worldwide. Anti-viral CD8⁺ T lymphocytes responding to IAV infection are believed to eliminate virally infected cells by direct cytolysis but may also contribute to pulmonary inflammation and tissue damage via the release of pro-inflammatory mediators following recognition of viral antigen displaying cells. We have previously demonstrated that IAV antigen expressing inflammatory cells of hematopoietic origin within the infected lung interstitium serve as antigen presenting cells (APC) for infiltrating effector CD8⁺ T lymphocytes; however, the spectrum of inflammatory cell types capable of serving as APC was not …

Beyond Biases And Barriers: Incorporating Women Into International Clinical Research, Bridget R. Nugent

Journal of Interdisciplinary Feminist Thought

The application of ethical principles in medical research has been a challenging issue because of the multiplicity of health care systems and the variations that exist in standards of care around the globe. This paper addresses the human rights issues that arise from the unethical treatment of women in clinical research worldwide. It includes the history of international human rights legislation as well as the problems that arose because of the exclusion of women from clinical trials. This paper includes a model for ethical clinical research based on the theories of a biologist and human rights scholar and a bio-ethicist, …

Volume Cxxx, Number 2, October 5, 2012, Lawrence University

The Lawrentian

No abstract provided.

Prevalence And Determinants Of Human Papillomavirus Infection And Cervical Lesions In Hiv-Positive Women In Kenya, H De Vuyst, N R. Mugo, M H. Chung, K P. Mckenzie, E Nyongesa-Malava, V Tenet, J W. Njoroge, S R. Sakr, C Jlm Meijer, P Jf Snijders, Farzana Rana, S Franceschi

Pathology, East Africa

Background: We assessed the association of human papillomavirus (HPV) infection and cervical intraepithelial neoplasia (CIN) with various characteristics, CD4 count and use of combination antiretroviral therapy (cART) among HIV-positive women.

Methods: Cross-sectional study of 498 HIV-positive women who underwent HPV PCR-based testing, cytology, and systematic cervical biopsy.

Results: In all, 68.7% of women were HPV-positive, 52.6% had high-risk (hr) HPV, and 40.2% multiple type infections. High-risk human papillomavirus-positivity did not vary significantly by age but it was negatively associated with education level. The most frequent types in 113 CIN2/3 were HPV16 (26.5%), HPV35 (19.5%), and HPV58 (12.4%). …

Hsv-1 Latent Rabbits Shed Viral Dna Into Their Saliva, James M. Hill, Nicole M. Nolan, Harris E. Mcferrin, Christian Clement, Timothy P. Foster, William P. Halford, Konstantin G. Kousoulas, Walter J. Lukiw, Hilary W. Thompson, Ethan M. Stern, Partha S. Bhattacharjee

Faculty Publications

Background: Rabbits latent with HSV-1 strain McKrae spontaneously shed infectious virus and viral DNA into their tears and develop recurrent herpetic-specific corneal lesions. The rabbit eye model has been used for many years to assess acute ocular infections and pathogenesis, antiviral efficacy, as well as latency, reactivation, and recurrent eye diseases. This study used real-time PCR to quantify HSV-1 DNA in the saliva and tears of rabbits latent with HSV-1 McKrae. Methods. New Zealand white rabbits used were latent with HSV-1 strain McKrae and had no ocular or oral pathology. Scarified corneas were topically inoculated with HSV-1. Eye swabs and …

Clostridium Septicum Growth From A Total Knee Arthroplasty Associated With Intestinal Malignancy: A Case Report, Demetri M. Economedes, Jerome Santoro, Carl A. Deirmengian

PCOM Scholarly Works

BACKGROUND: Previous reports of infection with Clostridium septicum have identified an unexpected association with concurrent malignancy. The reported rate of associated malignancy has been found to be as high as 81 percent. The purpose of this case report was to present a case of a total knee arthroplasty infected with C. septicum and the subsequent finding of an occult colonic malignancy.

CASE PRESENTATION: A 74 year-old man underwent uneventful bilateral total knee arthroplasties. Two weeks post-operatively, he presented with acute swelling, redness and pain of the left knee. Aspiration of the knee was sent for cell count and …

Clinic Connection: Fall 2012, Centracare Clinic

Clinic Connection

• President’s Message: "Transitioning into retirement"
• Meet our new Clinic President
• Introducing our new CentraCare Clinic Specialists
• Bariatric surgery indications for patients with diabetes
• The penumbra is key in stroke treatment
• New, Web-based tool helps to calculate fracture risk

Tlr8: The Forgotten Relative Revindicated, Jorge L. Cervantes, Bennett Weinerman, Chaitali Basole, Juan C. Salazar

UCHC Articles - Research

The endosomal Toll-like receptors (TLRs) TLR3, TLR7, TLR8 and TLR9 are important in sensing foreign nucleic acids encountered by phagocytes. Because TLR8 was initially thought to be non-functional in mice, less is known about TLR8 than the genetically and functionally related TLR7. Originally associated with the recognition of single-stranded RNA of viral origin, there is now evidence that human TLR8 is also able to sense bacterial RNA released within phagosomal vacuoles, inducing the production of both nuclear factor (NF)-κB-dependent cytokines and type I interferons (IFNs), such as IFN-β. The functions of TLR8 extend beyond the recognition of foreign pathogens and …

Stonehill Alumni Magazine Summer/Fall 2012, Stonehill College Office Of Communications And Media Relations

Stonehill Alumni Magazine

This issue of the magazine includes the following features:

• Who Knew?: What do the Tin Man, Aerosmith's Steven Tyler and a bull cemetery all have in common? You'll see on page 14, as SAM highlights some little-known facts and obscurities about Stonehill. By Martin McGovern
• Lost But Found: How Alina Favazza '14 arrived at Stonehill is anything but a typical story. Read about her journey from a Romanian orphanage to her family in America, who never stopped searching for her. By Maura King Scully
• Mass Effect: With Election Day around the corner, Stonehill experts weigh in on why Bay State …

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Benchmarks 2012, October 5, The Rockefeller University

BenchMarks 2012

BenchMarks. Friday, October 5, 2012

The community newsletter of The Rockefeller University

BenchMarks is published monthly and is distributed on the campus of The Rockefeller University. It produced by the Office of Communications and Public Affairs

Epidemiology Of Tuberculosis In Ohio, Usha Bala Vayuvegula

Master of Public Health Program Student Publications

Background: Tuberculosis (TB) is a global infectious disease often associated with HIV. Study of the distribution and epidemiologic trends may help target prevention and control measures towards high risk areas and groups.

Objective: To determine TB trends in four counties in Ohio, i.e. Franklin, Cuyahoga, Hamilton and Montgomery counties, and to explore differences in distribution of cases across gender, age groups and races.

Methods: TB surveillance data was collected from the Ohio Department of Health website for 12 years (1999-2011). Mean TB rates across gender were compared using the two sample t-test. One way ANOVA was used to compare means …

Living What You Learn

Madison Magazine

Huber Residential Learning Community

The Western Michigan University Magazine, Fall 2012, Western Michigan University

Western Michigan University Magazine (1997-present)

• Learning in the 21st Century: Initiative promotes teaching, student services that keep pace with a changing student body
• International Odysseys: Student’s studies take him across the globe in a year
• Gerontology Center: New center created ahead of predicted population boom in elder adults
• Overcoming Bias: Professor’s book addresses threats to journalistic objectivity
• Distinguished alumni winners: Two are honored with annual award
• Reporting in Post-War Iraq: Alumnus creates news outlet covering oil in the war-torn nation
• From Scientist to Schoolteacher? WMU prepares engineers and other technical professionals to teach in “high-need” public schools
• New Sangren
• University News
• Campus Quick Reads
• Classnotes …

Pharmacy Matters - October 2012, University Of Mississippi. School Of Pharmacy

Pharmacy Matters Newsletters

Featured stories: "Hospital pharmacist receives UM's Outstanding Young Alumni Award," "New assistant dean has passion for helping students," "Former dean honored for 'shaping' pharmacy profession," "RxSync ® helps improve community pharmacy care," "Presidential Scholarship winner honored at NCPA convention," "Faculty recognized for research, innovation and service"

Dipl 6277 Aa Global Health, Bioterrorism, And International Security, Li-Wen Zhang Phd

Diplomacy Syllabi

In today’s world, international trade and travel threaten epidemics by transporting and spreading infectious disease globally at jet speed. The growing risk of exposure to infectious disease, coupled with the looming threat of bioterrorism, creates a situation in which health and security are intersecting with greater frequency. This development parallels post-Cold War efforts to redefine the concept of security to encompass new global challenges. To what extent does health fit this new security agenda? What are the major linkages between health and security? Should other global health challenges (e.g., non-communicable chronic diseases) be framed as security problems that demand attention …

Awareness Of Type Ii Diabetes In The Developing World: Case Study In Binh Du’O’Ng, Vietnam, Anna Hong Le

Independent Study Project (ISP) Collection

Vietnam’s rapid economic development after 1986 forever changed the lifestyle of the Vietnamese. Economic development has highly impacted behavior, “changing from a traditional lifestyle to an industrial lifestyle [increasing] noncommunicable diseases (NCDs) : diabetes, overweight, high blood pressure, and high cholesterol disorders” (Danh, Personal Interview). With the increase of NCDs within the country, it is important to focus on awareness education that motivates the population especially those living in the urban sector to practice healthy behaviors. This study project focuses on the evaluating the reach and effectiveness of current diabetes awareness educational materials. One week was spent in Ha Noi, …