Digital Commons Network^™

Dermatophytic Contaminations In Sport Centres Of Jundishapur University Of Medical Sciences, Ahvaz, Iran, Ali Zarei Mahmoudabadi, Sara Rahnemaei

Turkish Journal of Medical Sciences

No abstract provided.

Determination Of Changes In The Basal Metabolic Rate And Body Composition Of Patients With Chronic Active And Inactive Hepatitis B Infection Using Bioelectrical Impedance Analysis*, Gökhan Unutmaz, Süda Teki̇n Koruk, Cemi̇l Sert

Turkish Journal of Medical Sciences

To examine changes in the basal metabolic rate and body composition of patients with chronic inactive and active hepatitis B (HBV) infection as measured using single frequency bioelectrical impedance analysis (BIA) and to investigate the convenience of this method for follow-up with these patients. Materials and methods: Twenty patients with chronic inactive HBV infection, 22 with chronic active HBV infection, and 43 healthy subjects were enrolled in the study. Using single frequency BIA and basal metabolic rate (BMR), the resistance and body composition of all participants were measured. Results: A total of 85 subjects (31 female and 54 male) with …

Evaluation Of Radiological Findings In 160 Adult Patients With Tuberculous Meningitis, Kadri̇ye Yaşar, Fi̇li̇z Pehli̇vanoğlu, Ahmet Şengöz, Gönül Şengöz

Turkish Journal of Medical Sciences

To evaluate the radiological findings of 160 adult patients with tuberculous meningitis (TBM). Materials and methods: Using a standard data collection form, 160 patients with TBM who had been followed for 11 years were assessed retrospectively. Cranial imaging results were obtained by computed tomography (CT) and magnetic resonance imaging (MRI), and pulmonary findings were obtained by chest X-ray and CT. Tuberculomas were assessed with a nominal tuberculoma classification index (TCI) scale. Results: Of the 160 patients, 80 were males and the mean age was 32.18 ± 13.62 years (range: 14-78). On admission, 84% were in stages II or III; 27 …

Clinical Appearance Of Brucellosis In Adults: Fourteen Years Of Experience, Behi̇ce Kurtaran, Aslihan Candevi̇r, Ayşe Seza İnal, Süheyla Kömür, Özay Akyildiz, Neşe Saltoğlu, Hasan Sali̇h Zeki̇ Aksu, Yeşi̇m Taşova

Turkish Journal of Medical Sciences

To indicate the clinical course and results of brucellosis in our region during the recent years, and to compare these findings to the literature. Materials and methods: This study was based on a review of the medical records of adult patients older than 14 years who were followed with the diagnosis of brucellosis from March 1997 to October 2010. Results: Included in this analysis were 317 patients, including 136 males (43%), with an average age of 40 ± 17 years. In 66 patients (21%), reproduction of Brucella was identified in the blood. Of the patients, 61% were identified as having …

In Vitro Efficacy Of Hyperbaric Oxygen Therapy Against Leishmania Tropica Promastigotes And Amastigotes, Özgür Koru, Soykan Özkoç, Kemal Şi̇mşek, Gürkan Mert, Hakan Ay, Seray Töz, Mehmet Tanyüksel

Turkish Journal of Medical Sciences

Aim: To assess the efficiency of hyperbaric oxygen (HBO) therapy on L. tropica, which is the major causative agent of cutaneous leishmaniasis in Turkey. Materials and methods: The effects of HBO on Leishmania tropica promastigote and amastigote forms were studied at a pressure of 2.5 atmosphere absolute (ata). We examined the cytotoxic effect of HBO on promastigotes using the trypan blue exclusion test and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) dye-reduction assay. To investigate the effects of HBO treatment on the growth of the promastigotes, HBO-treated and non-HBO-treated cell culture flasks were incubated at 26 °C for 3 days, while the effects …

Transient Bradycardia In Patients With Crimean-Congo Hemorrhagic Fever, Serpi̇l Erol, Zülal Özkurt, Kemaletti̇n Özden, Mehmet Parlak, Mustafa Kemal Erol

Turkish Journal of Medical Sciences

To determine the features and clinical course of bradycardia in patients with Crimean-Congo hemorrhagic fever (CCHF). Materials and methods: Between May 2002 and September 2010, a total of 380 patients with CCHF were followed. All patients who had transient bradycardia during this period were included in the study. Results: A total of 14 patients had an episode of bradycardia. All patients were in sinus rhythm. Three patients had clinical symptoms of bradycardia; atropine was administered to them. In the other patients, bradycardia resolved spontaneously. No patient had underlying conditions for bradycardia. Bradycardia appeared 7.0 ± 1.7 days after the first …

Effects Of Ankaferd Hemostat On The Synovial Fluid Of Patients With Osteoarthritis, Mehmet Aki̇f Öztürk, Zeli̇ha Koçak Tufan, Mehmet Derya Demi̇rağ, İbrahi̇m Celaletti̇n Haznedaroğlu

Turkish Journal of Medical Sciences

Ankaferd Blood Stopper (ABS) is a novel topical hemostatic agent with antiinfective, wound healing, and antineoplastic properties. In this study, we evaluated the macroscopic and biochemical effects of ABS in the joint fluid of patients with osteoarthritis. Materials and methods: Synovial fluid samples were obtained from 10 patients with osteoarthritis (5 women, 5 men; mean age 57.6 ± 11.2 years). From each patient, 4 mL of synovial fluid was drawn and put into 2 different serum separator tubes, and 1 mL of ABS was added to the first sample and 1 mL of 0.9% saline was added to the second …

Chest Radiography And Computed Tomography Findings Of Cases With Pandemic Influenza A (H1n1/09) Infection, Pinar Nerci̇s Koşar, Zeli̇ha Koçak Tufan, Eli̇f Ergün, Hasan Yi̇ği̇t, Uğur Koşar, Ali̇ Pekcan Demi̇röz

Turkish Journal of Medical Sciences

To review the radiological findings of the chests of swine flu patients whose infections were confirmed clinically and/or by laboratory tests. Materials and methods: This study was conducted in the radiology and infectious diseases departments of a tertiary care hospital, Ankara Training and Research Hospital, Ankara, Turkey. The X-ray and thorax computed tomography (CT) findings of swine flu patients were evaluated. Results: Included were 53 cases of swine flu. Thirty-eight of the patients (72%) underwent an initial chest X-ray and 17 (32%) underwent thorax CT examinations. The mean age of the patients was 41 years; 23 (43%) patients were male …

Characteristics Of Patients Transferred By Air: A Descriptive Epidemiologic Study, Ataman Köse, Beri̇l Köse, Ayça Açikalin Akpinar, Özlem Köksal, Şule Aydin, Erol Armağan

Turkish Journal of Medical Sciences

To analyze the characteristics of patients transferred by air ambulance in the eastern Anatolia region of Turkey. Materials and methods: We retrospectively evaluated the records of patients transferred by air ambulance between January 2010 and December 2010. Demographics and medical data of the patients, geographic conditions, and flight duration data were all analyzed. Results: A total of 241 patients were included in the study, of whom 51% were men and 49% were women. The majority of the patients were between 0 and 1 year old (40.2%). In the adult patients, the most commonly seen diagnoses were trauma (31.6%), obstetric problems …

Do Incubation Temperature, Incubation Time, And Carbon Dioxide Affect The Chromogenic Properties Of Chromagar?, Di̇lek Yeşi̇m Meti̇n, Hüsnü Pullukçu, Süleyha Hi̇lmi̇oğlu Polat, Ramazan İnci̇, Zeki̇ye Emel Tümbay

Turkish Journal of Medical Sciences

On CHROMagar medium Candida species form different colors; thus, the medium enables the differentiation of these species from each other as well as from other Candida species. The aim of this study is to investigate the effect of incubation temperatures, incubation times, and CO_2 on the chromogenic properties of CHROMagar. Materials and methods: A total of 112 strains of Candida spp. were used. A 0.5 McFarland suspension of each strain was inoculated onto CHROMagar with a calibrated loop and incubated at 26 °C and 35 °C for 24-48 h in normal atmosphere and in an atmosphere of 5% CO_2. The …

Tularemia As A Result Of Outdoor Activities For Children In The Countryside, Şaban Gürcan, Gamze Varol Saraçoğlu, Aynur Karadeni̇zli̇, Emi̇ne Neşe Özkayin, Şemsi̇ Zafer Öztürk, Cemal Çi̇çek, Bi̇nay Vatansever

Turkish Journal of Medical Sciences

To investigate the features of a new tularemia outbreak that occurred in the Thrace region. Materials and methods: The research team visited the village after the identification of the index case. Serum and throat samples were taken from 41 villagers who were examined, and environmental samples were taken in order to identify the source of the outbreak. Culture, serology, and molecular methods were used to search for Francisella tularensis in these samples. Results: A total of 8 children were diagnosed with tularemia. The adults and all of the other children were seronegative for tularemia. All of the patients had a …

Molecular Typing And Sequencing Of Adenovirus Isolated From A Conjunctivitis Outbreak In A Neonatal Intensive Care Unit By Pcr, Candan Çi̇çek, Tamer Şanlidağ, Betül Si̇yah Bi̇lgi̇n, Hüsnü Pullukçu, Si̇nem Akçali, Özge Altun Köroğlu, Mehmet Yalaz, Ni̇lgün Kültürsay

Turkish Journal of Medical Sciences

We aimed to evaluate the molecular typing of adenovirus isolated during an epidemic at the Ege University Children's Hospital neonatal intensive care unit (NICU). Materials and methods: During the NICU outbreak management, 40 clinical samples (from 15 newborn infants and 25 health care providers) were sent to a microbiology laboratory in viral transport media. All the samples were processed using a direct fluorescent antibody (DFA) test and a shell vial cell culture followed by adenovirus polymerase chain reaction (PCR) and DNA sequencing. PCR and DNA sequencing for adenovirus hexon gene hypervariable regions 1-6 were done after DNA extraction from clinical …

Minimum Inhibitory And Minimum Bactericidal Concentrations Of Boron Compounds Against Several Bacterial Strains, Murat Tolga Yilmaz

Turkish Journal of Medical Sciences

Boron compounds are essential micronutrients for many organisms. However, they negatively affect plant, soil, and water microflora if excessive amounts exist in irrigation water. Therefore, this study aimed to define the minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of boric acid and borax by selecting the bacteria that can survive in all environments. Materials and methods: The antibacterial efficacy of boric acid and borax against several bacterial strains was evaluated 3 times with the macrodilution broth method. Results: The MICs and MBCs of boric acid were obtained as 3.80 mg/mL, 3.80 mg/mL, 7.60 mg/mL, and 7.60 mg/mL against …

Investigating Virulence Factors Of Clinical Candida Isolates In Relation To Atmospheric Conditions And Genotype, Melek İnci̇, Mustafa Altay Atalay, Ayşe Nedret Koç, Erkan Yula, Ömer Evi̇rgen, Süleyman Durmaz, Gonca Demi̇r

Turkish Journal of Medical Sciences

To investigate some virulence factors in Candida species isolated from patients with suspected invasive fungal infection and to identify their relationship with Candida genotypes. Materials and methods: Overall 45 isolates (20 Candida albicans and 25 non-albicans Candida spp.) genotyped by rep-PCR were included in this study. Virulence factors were studied in both aerobic and anaerobic conditions. In isolates, egg yolk agar was used for determining phospholipase activity, while bovine serum albumin agar was used for proteinase activity, Tween-80 medium for esterase activity, and Sabouraud dextrose agar with sheep blood for hemolysin activity. Biofilm formation was detected by the microplate method. …

Assessment Of Haematology Patients With Confirmed H1n1 Positivity, Füsun Özdemi̇rkiran, Hüsnü Pullukçu, Candan Çi̇çek, Seçki̇n Çağirgan, Murat Tombuloğlu, Fi̇li̇z Vural, Güray Saydam

Turkish Journal of Medical Sciences

H1N1 influenza virus infections in immunosuppressive patients cause complications. Clinical and laboratory findings of H1N1 positive haematology patients were evaluated in this study. Materials and methods: The "H1N1 Swine Influenza Suspicious Case Notification Form and Inpatient Follow-up Form" was prepared for 15 patients with suspected H1N1 infection between October 2009 and May 2010. H1N1 was detected by real-time RT-PCR assay. For all cases medical records were reviewed for clinical, demographic, and haematologic information. Results: H1N1 positivity was confirmed using real-time RT-PCR in 9 out of 15 patients (11 men, 4 women). One of the 9 patients had been followed up …

Problem Of Antibiotic Resistance In Patients With Acute Bacterial Cystitis And Treatment Options, Ahmet Karakaş, Vedat Turhan

Turkish Journal of Medical Sciences

No abstract provided.

Disease-Branding And Drug-Mongering: Could Pharmaceutical Industry Promotional Practices Result In Tort Liability?, Jason S. Cetel

Seton Hall Law Review

No abstract provided.

Buried Stars In Salman Rushdie’S The Ground Beneath Her Feet, Stanka Radović

Reconstruction: Studies in Contemporary Culture

Rushdie's own global stardom, built on his celebration of migrancy and uprootedness as well as on the “fatwa” that marked him as a global target, informs his 1999 novel The Ground Beneath Her Feet. In this novel, Rushdie's usual focus on crossing boundaries and challenging national loyalties follows the musical stardom of his two protagonists, Vina Apsara and Ormus Cama. They not only evoke famous pop stars, like Madonna or Michael Jackson, but also the trans-historical allegiance to the most enduring myth of poetic dislocation, the myth of Orpheus. In exploring the musical star's potential to cross the impossible …

Arctic Justice: Addressing Persistent Organic Pollutants, Elizabeth Burleson, Stephanie Dodson Dougherty

Minnesota Journal of Law & Inequality

No abstract provided.

Stress Hormone In White-Throated Sparrows (Zonotrichia Albicollis) Is Not Influenced By The Cleanliness Of A Cotton Bag, Nidun Daniel, Gregory B. Cunningham

Biology Faculty/Staff Publications

Bird banding stations are used throughout North America to trap and band birds, which allow researchers and government agencies to monitor populations, migration routes, health and a variety of other elements of avian physiology and biology. Birds are commonly trapped in mistnets, placed into a cotton bag, and brought to a research station where they are banded, weighed, measured and released. On some days, the number of birds caught may be so high that birds are left to hang in the bags for 10 – 20 minutes while other birds are processed. During this time in the bag the birds …

The Biology And Management Of Brucellosis In Yellowstone Bison, John Joseph Treanor

Theses and Dissertations--Biology

Disease management along the boundaries of wildlife reserves is a growing conservation problem worldwide, as infected wildlife can migrate outside protected areas and pose a threat to livestock and human health. The bison Bison bison population in Yellowstone National Park has long been infected with Brucella abortus, the bacterium causing bovine brucellosis. Concern over migratory bison transmitting B. abortus to cattle herds on lands adjacent to Yellowstone has led to proposals for bison vaccination. Model simulations suggest that vaccination is unlikely to eradicate B. abortus from Yellowstone bison but could be an effective tool for reducing the level of …

Male Farmers Coping With Loss Of Spouse: Impacts On Farming Operation And Family Life, Daniel O. Wilson

Theses and Dissertations--Community & Leadership Development

Losing a spouse is as devastating an experience anyone will ever deal with in his or her life. Research, however, shows that men have a harder and longer time coping with the loss of a spouse than women. When the widower’s profession is farming, there are no resources to specifically help that individual with their loss. The purpose of this research was to gain insight into the lives of widowed farmers with particular focus on transitions in their farming operation and their family life. Through their stories, we learn what is happening before the loss of the female spouse on …

Investigating The Role Of Prion Protein Polymorphisms On Prion Pathogenesis, Eri Saijo

Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics

Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are lethal and infectious neurodegenerative diseases of humans and animals. The misfolding of the normal, or cellular isoform of the prion protein (PrP^C) into the abnormal disease-associated isoform of PrP (PrP^Sc) could change the properties of PrP, consequently, PrP^Sc has lethal infectivity to transmit diseases. The proteinaceous infectious particle consisting mainly of PrP^Sc is called prion. Transmissibility of prions is strongly influenced by multiple factors including PrP polymorphisms, species barriers (PrP sequence specificity) and prion strains (conformational specificity) by unknown mechanisms. Even though the ability …

The Role Of Intestinal Epithelial Cells And The Regulation Of The Polymeric Immunoglobulin Receptor In Homeostasis And Inflammation, Aubrey Leigh Frantz

Theses and Dissertations--Microbiology, Immunology, and Molecular Genetics

The mammalian intestine harbors an estimated 100 trillion microorganisms, which normally maintain a mutually beneficial relationship with the host. The intestinal epithelium consists of a single layer of intestinal epithelial cells (IECs) that provides a physical barrier as well as innate immune defense, preventing this vast community of microbes from entering host tissues. Secretory immunoglobulin A (SIgA) acts as the first line of antigen-specific immunity at the interface between the gut microbiota and the intestinal epithelium. Polymeric IgA secreted by plasma cells in the intestinal lamina propria is transported across IECs by the polymeric immunoglobulin receptor (pIgR). Defects in epithelial …

Evaluating Retention In Medical Care And Its Impact On The Health Outcomes Of Individuals Living With Human Inmmunodeficiency Virus, Timothy N. Crawford

Theses and Dissertations--Epidemiology and Biostatistics

In the last few years, engagement in medical care among individuals living with HIV has become a major priority among HIV medical providers and public health researchers. Engagement in medical care is an important concept as it involves the process of linking newly diagnosed individuals into medical care and retaining those individuals in care throughout the course of their infection. Although there have been major advances in the management of HIV, like the advent of Highly Active Antiretroviral Therapy, morbidity and mortality due to HIV cannot be fully reduced if the individual does not optimally retain in care. Retention in …

The Relationship Of Social Stress, Economic Hardship, And Psychological Distress To Addiction Severity Among Kentucky Substance Abuse Treatment Participants, Elizabeth A. Wahler

Theses and Dissertations--Social Work

Stress is associated with poor mental health, specifically anxiety and depression, and stress and mental health problems are predictors of substance dependence and relapse. Social characteristics, such as racial/ethnic minority status, female gender, and low socioeconomic status, are often associated with increased psychological distress and substance use disorders. Pearlin’s social stress theory postulates that this association is due to increased exposure to stress and subsequent experiences of distress related to social disadvantage and decreased access to resources for coping with stress. This project uses a social stress theoretical perspective to examine predictors of substance use after treatment entry and follow-up …

Localization And Functional Characterization Of Oatp4c1 Transporter In In Vitro Cell Systems And Human/Rat Tissues, Kuei-Ling Kuo

Theses and Dissertations--Pharmacy

The organic anion transporting polypeptide 4c1 (Oatp4c1) was previously identified as a novel uptake transporter predominantly expressed at the basolateral membrane in the rat kidney proximal tubules. Its functional role was suggested to be a vectorial transport partner of an apically-expressed efflux transporter for the efficient translocation of physiological substrates into urine, some of which were suggested to be uremic toxins. In vitro studies in polarized cell lines showed that upon transfection rat Oatp4c1 localizes at the apical membrane. The objectives of this project were to further validate the subcellular localization of Oatp4c1/OATP4C1 in rat and human tissues as well …

Glycerolipids And The Plant Cuticle Contribute To Plant Immunity, Qing-Ming Gao

Theses and Dissertations--Plant Pathology

The conserved metabolites, oleic acid (18:1), a major monounsaturated fatty acid (FA), and glycerol-3-phosphate (G3P) are obligatory precursors of glycerolipid biosynthesis in plants. In Arabidopsis, the SSI2-encoded SACPD is the major isoform that contributes to 18:1 biosynthesis. Signaling induced upon reduction in oleic acid (18:1) levels not only upregulates salicylic acid (SA)-mediated responses but also inhibits jasmonic acid (JA)- inducible defenses. I examined the transcription profile of ssi2 plants and identified two transcription factors, WRKY50 and WRKY51. Although the ssi2 wrky50 and ssi2 wrky51 plants were constitutively upregulated in SA-derived signaling, they were restored in JAdependent defense signaling. Not only …

The Transmission Dynamics Of Equine Herpesvirus Type 1 (Ehv-1) Infection In Outbreaks Characterized Predominately By Neurologic Or Respiratory Illness, Barry Jay Meade

Theses and Dissertations--Veterinary Science

Formalized epidemiological field investigations were conducted to compare and contrast the transmission dynamics of EHV-1 neurological disease among horses stabled at Churchill Downs Racetrack, Louisville, Kentucky and of EHV-1 respiratory illness among horses stabled in the student barn at Murray State University. Differences were assessed by means of statistical and mathematical modeling techniques applied to survey and biological data collected over the course of the respective disease events.

Regression methods applied to survey data enabled the construction of a statistical model to predict a date of onset of illness for horses within each equine cohort. Comparisons of the epidemic curves …

Development Of Molecular Diagnostic Assays For Equine Respiratory Viruses And Analysis Of The Role Of Equine Arteritis Virus Envelope Proteins In The Early Events Of Virus Entry, Zhengchun Lu

Theses and Dissertations--Veterinary Science

There is an urgent need for detection of viral respiratory pathogens to identify the causal agent(s) involved and to prevent the spread of related diseases. The first part of this dissertation focuses on development, optimization and validation of Real-time reverse transcription polymerase chain reaction (rRT-PCR) assays for the detection of several common equine viral pathogens: equine arteritis virus (EAV), equine influenza virus and equine rhinitis viruses A and B. Emphasis of the second part of this dissertation is on studying the role of EAV envelope proteins in virus attachment and entry. Using an infectious cDNA clone of EAV and reverse …