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Gunshot (Excerpt From “Sun On Ice,” A Novel In Progress), Luis Cabalquinto

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Drosophila Activated Cdc42 Kinase Has An Anti-Apoptotic Function., Jessica A. Schoenherr, J Michelle Drennan, Juan S. Martinez, Madhusudana Rao Chikka, Mark C. Hall, Henry C. Chang, James C. Clemens

Department of Biochemistry Faculty Publications

Activated Cdc42 kinases (Acks) are evolutionarily conserved non-receptor tyrosine kinases. Activating somatic mutations and increased ACK1 protein levels have been found in many types of human cancers and correlate with a poor prognosis. ACK1 is activated by epidermal growth factor (EGF) receptor signaling and functions to regulate EGF receptor turnover. ACK1 has additionally been found to propagate downstream signals through the phosphorylation of cancer relevant substrates. Using Drosophila as a model organism, we have determined thatDrosophila Ack possesses potent anti-apoptotic activity that is dependent on Ack kinase activity and is further activated by EGF receptor/Ras signaling. Ack anti-apoptotic signaling …

Community Involvement As A Tool For International Policy: Realizing The Great Lakes Water Quality Agreement, Michael D. Eriksen Jr.

Honors Theses

Whether present in abundance or known for its scarcity, water defines the regional and geographical identities of people. It defines political and ecological boundaries globally. Water paucity and quality in burgeoning populations has been a catalyst for creative resource management policies. Conservation of water resources, in practice, has still not improved however. As a result, the health and stability of the Great Lakes as a natural resource is threatened. The Great Lakes region includes two countries, eight states, two provinces, and over 200 tribal and native influences. International agreements, such as the Boundary Waters Treaty of 1909 (BWT) and the …

An Experimental Study On The Interaction Of Coaxial And Co-Rotating Vortex Rings, Jagannadha Reddy Satti

Engineering

The study investigated the role of formation time, Reynolds Number, and non-dimensional frequency number, the three most significant parameters in the dynamics of vortex rings, in the interaction between co-axial and co-rotating vortex rings and in the ring behaviors of merging and leapfrogging. To generate and investigate vortex rings with the required characteristics, two laminar vortex rings were generated consecutively from a piston-cylinder apparatus such that the rings propagated in the same direction and that the spatial separation between them decreased until they began merging. Using digital particle image velocimetry to measure the flow fields as well as the trajectory …

Louisiana State University Health Sciences Center - 2012 - 138th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 138th Commencement of LSU Health Sciences Center - New Orleans held May 17, 2012.

Reflections Of Self, Melissa Athey

Theses and Dissertations

I vacillate between all extremes, beauty vs. ugly, internal vs. external, micro vs. macro. It is these disparate notions that inspire what I make. We cannot ever see ourselves objectively, but does that mean we shouldn’t try? This thesis is my attempt to dissect what I created in my 2 years at Virginia Commonwealth University, my exploration of the illness within and the psychological nature of how we go about hiding our insecurities.

Time In Wilfrido D. Nolledo’S Fiction, Gerardo Z. Torres

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Eduardo Masferre And The Phillippine Cordillera, Ma. Luisa Aguilar-Cariño

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Philippine Indigenous Aesthetics, David B. Baradas

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Magkano Ba Ang Asawa Mo? Paunang Salita Sa Dulang “Bingo” Bingo!, Ricardo L. Saludo

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

Shoreline Distribution And Landscape Genetics Of Bears In A Recently Deglaciated Fjord: Glacier Bay, Alaska, Tania M. Lewis

Biological Sciences

To further knowledge of mammalian colonization patterns following deglaciation, I used occupancy modeling to estimate black and brown bear shoreline distribution of Glacier Bay and how these distributions relates to the number years of land exposure and post glacial plant and stream succession. I also conducted microsatellite genetic analysis of brown bear hair and tissue to determine contemporary population structure throughout the park and how it relates to landscape features and surrounding populations. Closed forest cover within 1 km of the study site was a strong positive predictor of black bear occurrence. Brown bears were detected at 100% of sites …

Central Co2 Chemosensitivity In Tadpoles: Impairment And The Role Of Serotonin, Spencer D. Audie

Biological Sciences

Nicotine and ethanol are known neuroteratogens and prenatal exposure correlates with Sudden Infant Death Syndrome (SIDS), which is thought to result from failure to maintain pH homeostasis through respiratory adjustments. This failed homeostatic control is believed to be serotonergic in origin. In previous studies nicotine or ethanol exposure ablated the robust hypercapnic response of early-stage tadpoles. These findings lead us to question if the ablation occurred through a serotonindependent mechanism. This study investigated the role of serotonin (5- HT) in the nicotine- or ethanol-induced abolishment of the hypercapnic response. We found that toxin-exposed animals were insensitive to hypercapnia and also …

Biochemical And Microbiological Assessments Of Dried Alaska Pink Salmon, Red Salmon And Pacific Cod Heads, Huseyin Biceroglu

Fisheries

Fish heads are generally considered as unsuitable byproducts for human consumption in the United States. The initial objective was to compare the moisture content and water activity levels on dried pink salmon (Oncorhynchus gorbuscha) and dried red salmon (O. nerka) using different temperature and time integration. The secondary objective was to compare shelf life characteristics, rancidity and mold growth, between dried pink dried salmon and dried Pacific cod (Gadus macrocephalus) heads stored for up to 180 days at the ambient temperature (21°C) for East African seafood markets. The third objective was to assess the antioxidant effects for frozen and dried …

Delayed Effects Of Oil Exposure On Fish, Corinne E. Hicken

Fisheries

Polycyclic aromatic hydrocarbons (PAHs) are continuously added to aqueous environments through point source and non-point source pollution and can cause deleterious effects on exposed fish populations. Historically, studies have shown that acute PAH exposure causes only short-term effects in adult fish which were resolved when the exposure ended. Chronic exposure to PAHs, however -- even at the less susceptible juvenile and adult stages -- can cause a host of effects including lesions, lower body length and weight, and reduced swimming ability. More recently studies of embryonic fish have demonstrated that much lower PAH concentrations can cause lethal and sub-lethal effects …

Growth And Post-Harvest Quality Of Selected Pacific Oysters (Crassostrea Gigas) Cultured In Kachemak Bay, Alaska, And Puget Sound, Washington, In October Of 2009 And June Of 2010, Stuart Rendell Thomas

Fisheries

The primary objective of this project was to evaluate the growth, biochemical and fatty acid composition, physical and shell characteristics, and basic reproductive development of families of Pacific oysters (Crassostrea gigas) from the USDA-funded Molluscan Broodstock Program (MBP) planted in suspended culture in Kachemak Bay (KB), Alaska, and at an intertidal site in Thorndyke Bay (TB), Puget Sound, Washington. The MBP selects oysters to improve yields, growth, and survival, but little is known about the effects of selective breeding on other biological characteristics of selected oysters. Shell and meat characteristics of oysters from each of the seven highest-yielding MBP families …

A Total Environment Of Change: Exploring Social-Ecological Shifts In Subsistence Fisheries In Noatak And Selawik, Alaska, Katie J. Moerlein

Fisheries

Arctic ecosystems are undergoing rapid changes as a result of global climate change, with significant implications for the livelihoods of arctic peoples. In this thesis, I use ethnographic research methods to detail prominent environmental changes observed and experienced over the past few decades and to document the impact of these changes on subsistence fishing practices in the Inupiaq communities of Noatak and Selawik in northwestern Alaska. Using in-depth key informant interviews, participant observation, and cultural consensus analysis, I explore local knowledge and perceptions of climate change and other pronounced changes facing the communities of Noatak and Selawik. I find consistent …

Optical Properties& Energy Transfer Dynamics Of Atmospheric Species, Daniel K. Havey

Science Enabled by Photon Sources: Local Research Interests in Virginia

Our research group is interested in how light interacts with small molecules and particulate matter that are important to atmospheric chemistry and climate change. An active project currently being performed in the James Madison University Undergraduate Laser Laboratory involves a detailed mapping of energy transfer rates from excited or metastable states of atomic or molecular species. This talk describes a specific example study with potential relevance to the JLAMP VUV/Soft X-ray User Facility that would investigate relaxation dynamics of metastable Krypton atoms using two-photon photoacoustic spectroscopy at 819 nm and 124 nm. A study like this would provide useful reference …

The Federal Democratic Republic Of Ethiopia: Liberal Democratic Or Authoritarian Regime?, Solomon Terfa

African Social Science Review

The leaders of the Federal Democratic Republic of Ethiopia adopted their constitution on December 8, 1994. This analysis argues that the ethno-linguistic federal political system adopted by the founding members is problematic because the framers superimposed the constitution on the citizens dogmatically without thoroughly examining the country’s objective reality. Hence, the author contends that the ethnic federalist paradigm adopted in Ethiopia is diametrically opposed to the wishes and aspirations of the people as validated by a survey he conducted between 1992 and 1993. He draws from this, perhaps the first and only study on this pertinent topic, to argue his …

Integrin Activation By A Cold Atmospheric Plasma Jet, Olga Volotskova, Mary Ann Stepp, Michael Keidar

Anatomy and Regenerative Biology Faculty Publications

Current breakthrough research on cold atmospheric plasma (CAP) demonstrates that CAP has great potential in various areas, including medicine and biology, thus providing a new tool for living tissue treatment. In this paper, we explore potential mechanisms by which CAP alters cell migration and influences cell adhesion. We focus on the study of CAP interaction with fibroblasts and corneal epithelial cells. The data show that fibroblasts and corneal epithelial cells have different thresholds (treatment times) required to achieve maximum inhibition of cell migration. Both cell types reduced their migration rates by ~30–40% after CAP compared to control cells. Also, the …

In The Name Of God The Most Gracious The Most Merciful, Saud Alhassan Saud Abdulaziz Al Saud

Dissertations & Theses

This thesis explains the Islamic law that applies the Quran and Sunnah as a constitution, and the concept of Rahma. It will emphasize this concept by explaining the rigid law of Hudod, then elaborating on Rahma.

Egr-1 Induces Darpp-32 Expression In Striatal Medium Spiny Neurons Via A Conserved Intragenic Element., Serene Keilani, Samira Chandwani, Georgia Dolios, Alexey Bogush, Heike Beck, Antonis K Hatzopoulos, Gadiparthi N Rao, Elizabeth A Thomas, Rong Wang, Michelle E Ehrlich

Farber Institute for Neuroscience Faculty Papers

DARPP-32 (dopamine and adenosine 3', 5'-cyclic monophosphate cAMP-regulated phosphoprotein, 32 kDa) is a striatal-enriched protein that mediates signaling by dopamine and other first messengers in the medium spiny neurons. The transcriptional mechanisms that regulate striatal DARPP-32 expression remain enigmatic and are a subject of much interest in the efforts to induce a striatal phenotype in stem cells. We report the identification and characterization of a conserved region, also known as H10, in intron IV of the gene that codes for DARPP-32 (Ppp1r1b). This DNA sequence forms multiunit complexes with nuclear proteins from adult and embryonic striata of mice and rats. …

Conexão Subterrânea, No. 97, May 16, 2012, Karen Perez, Leda Zogbi, Roberto Cassimiro

KIP Articles

Nesta edição você saberá mais sobre os seguintes assuntos: - Gruta da Velha Duda é mapeada em Morro do Chapéu, Bahia - Audiências Públicas para criação do Parque Nacional Serra do Gandarela - Resgate da Memória: Walter Neves, Jô Soares e um petroglifo - Workshop sobre Espeleometria será realizado em Belo Horizonte - Mapeada Gruta da Pedra Pintada, em Roraima - Rocha despenca de Gruta na Cidade de Lapão - Proprioque?! - Lançamento dos livros 100 Árvores do Cerrado + Plantas e Morcegos - Comissão rejeita proposta que torna Caverna Área de Proteção Ambiental - Casal brasileiro morre durante mergulho …

Adrenergic Alpha-1 Pathway Is Associated With Hypertension Among Nigerians In A Pathway-Focused Analysis, Nicholas P. Reder, Bamidele O. Tayo, Babatunde Salako, Adesola Ogunniyi, Adebowale Adeyemo, Charles Rotimi, Richard S. Cooper

Faculty Publications

Background: The pathway-focused association approach offers a hypothesis driven alternative to the agnostic genome-wide association study. Here we apply the pathway-focused approach to an association study of hypertension, systolic blood pressure (SBP), and diastolic blood pressure (DBP) in 1614 Nigerians with genome-wide data. Methods and Results: Testing of 28 pathways with biological relevance to hypertension, selected a priori, containing a total of 101 unique genes and 4,349 unique single-nucleotide polymorphisms (SNPs) showed an association for the adrenergic alpha 1 (ADRA1) receptor pathway with hypertension (pp>10-5) SNPs offers a novel method for detecting the "missing heritability" of hypertension. These findings …

Girls Living Healthy, Gabrielle Hewson

Theses

My Master of Fine Arts Thesis Project, entitled Girls Living Healthy, is an educational web site for girls ages 8 to 108. It is designed to inform and teach them how to make healthier nutrition and, subsequently, lifestyle choices. This project combines my passion for healthier living with my skills in, and enjoyment of, writing, illustration, and web design. Girls Living Healthy includes hand-drawn illustrations, original and applied hardcoded scripting language, resource and links, a glossary of less common terms, a quick interactive game called "Mood Swings", and the culmination of over a year's personal research and participation. My overall …

Mapping Populations At Risk: Improving Spatial Demographic Data For Infectious Disease Modeling And Metric Derivation, Andrew J. Tatem, Susana Adamo, Nita Bharti, Clara R. Burgert, Marcia Castro, Audrey Dorelien, Gunter Fink, Catherine Linard, Mendelsohn John, Livia Montana, Mark R. Montgomery, Andrew Nelson, Abdisalan M. Noor, Deepa Pindolia, Greg Yetman, Deborah Balk

Publications and Research

The use of Global Positioning Systems (GPS) and Geographical Information Systems (GIS) in disease surveys and reporting is becoming increasingly routine, enabling a better understanding of spatial epidemiology and the improvement of surveillance and control strategies. In turn, the greater availability of spatially referenced epidemiological data is driving the rapid expansion of disease mapping and spatial modeling methods, which are becoming increasingly detailed and sophisticated, with rigorous handling of uncertainties. This expansion has, however, not been matched by advancements in the development of spatial datasets of human population distribution that accompany disease maps or spatial models. Where risks are heterogeneous …

Scavenger Receptor Cd36 Expression Contributes To Adipose Tissue Inflammation And Cell Death In Diet-Induced Obesity, Lei Cai, Zhen Wang, Ailing Ji, Jason M. Meyer, Deneys R. Van Der Westhuyzen

Internal Medicine Faculty Publications

OBJECTIVE: The enlarged adipose tissue in obesity is characterized by inflammation, including the recruitment and infiltration of macrophages and lymphocytes. The objective of this study was to investigate the role of the scavenger receptor CD36 in high fat diet-induced obesity and adipose tissue inflammation and cell death.

EXPERIMENTAL APPROACH: Obesity and adipose tissue inflammation was compared in CD36 deficient (CD36 KO) mice and wild type (WT) mice fed a high fat diet (60% kcal fat) for 16 weeks and the inflammatory response was studied in primary adipocytes and macrophages isolated from CD36 KO and WT mice.

RESULTS: Compared to WT …

Testing Crayfish Evolutionary Hypotheses With Phylogenetic Methods, Jesse W. Breinholt

Theses and Dissertations

This dissertation focuses on increasing the understanding of the evolution processes that have contributed to the diversification of freshwater crayfish. Chapter one estimates the divergence time of the three crayfish families and tests the hypothesis that diversification is tied to the break-up of Pangaea, Gondwanna, and Laurasia. I find that the families of crayfish diverged prior to or in association with the break-up of the three super continents. Chapter two addresses the evolutionary history of the genus Cambarus, using molecular data to test hypotheses of relationships based on chela and carapace morphology. The results provide evidence that the morphology used …

Butbut Riddles: From And Function, Norma N. Lua

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.

The Guardian, May 16, 2012, Wright State University Student Body

The Guardian Student Newspaper

Twelve page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

Abrogation And Appropriation: Post-Colonial Literature In The Philippines, E. Vallado Daroy

Philippine Studies: Historical and Ethnographic Viewpoints

No abstract provided.