Digital Commons Network^™

Keratin 6 As A Potential Biomarker Of Bladder Cancer Induced By Heavy Metals, Arsenic And Cadmium, Ling Cao

Theses and Dissertations

Arsenic and cadmium (Cd2+) are environmental carcinogens that have been implicated in the development of bladder cancer. However, there are no good in vitro model systems to study the development of bladder cancer caused by these carcinogens. Previous studies from this laboratory have shown that arsenite (As3+) and Cd2+ exposure can cause direct malignant transformation of an immortalized human urothelial cell line, the UROtsa. In the present study the repeatability of the transformation process was examined by isolating and characterizing 6 additional Cd2+- transformed lines and 5 additional As3+- transformed cell lines. All the transformed cell lines formed tumors when …

The Parthenon, September 7, 2012, Shane Arrington

The Parthenon

The Parthenon, Marshall University’s student newspaper, is published by students Monday through Friday during the regular semester and weekly Thursday during the summer. The editorial staff is responsible for the news and the editorial content.

Post-Translational Regulation Of The Dopamine Transporter, Amy E. Moritz

Theses and Dissertations

The dopamine transporter (DAT) is an integral membrane phosphoprotein found on dopaminergic neurons that mediates the presynaptic reuptake of dopamine and is a site of action for psychostimulants. Numerous DAT functions including efflux, uptake activity, and surface expression are regulated by protein kinase C (PKC) through unknown mechanisms. Basal and PKC stimulated phosphorylation of DAT occurs on multiple serines in the distal N-terminus, but the exact sites modified and the kinases involved are unknown. To address these issues, we examined in vitro phosphorylation of a recombinant DAT N-terminal tail peptide (NDAT). We found that NDAT is phosphorylated at multiple sites …

Heavy Metal Chemistry Of Sediments In Caves Of The Springfield Plateau, Missouri-Arkansas-Oklahoma: A Link To Subterranean Biodiversity, Travis M. Doughty, Aaron W. Johnson

The Compass: Earth Science Journal of Sigma Gamma Epsilon

We used X-ray fluorescence (XRF) to compare the heavy metal chemistry of sediments in caves in rural and urban areas to the chemistry of sediments from a control cave in a relatively undisturbed watershed in the Springfield (MO) Plateau. Sediment from Smallin Cave near Ozark, MO, the control cave, has the smallest peak sizes for Zn and Mn and a moderately-sized Pb peak. Sediment from the rural cave exhibited larger peaks of Zn and Mn and a smaller Pb peak. Sediment from the urban cave had the largest Zn, Mn and Pb peaks. Interestingly, smaller peak sizes appear to correlate …

Geology And Music, Dan Merriam

The Compass: Earth Science Journal of Sigma Gamma Epsilon

No abstract provided.

Using Macroinvertebrate Community Composition To Distinguish Between Natural And Anthropogenic Sedimentation, Amanda E. Schutt

Theses and Dissertations

Excess fine sediment from human activity is a major pollutant to streams across the U.S.; however, distinguishing human-induced sedimentation from natural fine sediment is complex. The U.S. Environmental Protection Agency recently implemented a protocol for the quantitative field assessment of human-induced sedimentation using measurements of stream geomorphology. Macroinvertebrate community composition, streambed sediment stability, and sediment composition were studied at 49 sites in the James River watershed in central Virginia. Sediment composition was found to be a stronger driver of community composition than sediment stability. Although I was not able to show that macroinvertebrate metrics were related to sediment stability independently …

Montana Kaimin, September 7, 2012, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Chanticleer | Vol 61, Issue 2, Jacksonville State University

Chanticleer

No abstract provided.

Kinetics Of Running On Arboreal Versus Terrestrial Substrates In Siberian Chipmunks, Eliza J. Dorsey

Undergraduate Research Posters 2012

Many mammals travel on both tree branches and flat ground in their natural habitat. Forelimbs were found to have the dominant role in braking on both substrates, while hindlimbs had the dominant role in propulsion on both substrates. However, the forelimb aided in propulsion more so than the hindlimbs contributed to braking on both substrates.

The Utah Statesman, September 11, 2012, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Good 5 Cent Cigar (9/6/2012), University Of Rhode Island

The Good 5 Cent Cigar (Student Newspaper Archives)

This is a digitized, downloadable version of the University of Rhode Island school newspaper.

Spartan Daily September 6, 2012, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 139, Issue 5

September 6, 2012, James Madison University

The Breeze, 2010-2019

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

September 6, 2012, Ohio University Board Of Trustees Meeting Minutes, Ohio University Board Of Trustees

Board of Trustees Meeting Minutes

Meeting minutes document the activities of Ohio University's Board of Trustees.

Commonwealth Times 2012-09-06

Commonwealth Times, 1969-

No abstract provided.

Anti-Cancer Drug Screening Of Dual Tubulin And Hsp27 Inhibitors With 2d And 3d Lung Cancer Cell Assays, Janine Maria Naim, Rati Lama

Undergraduate Research Posters 2012

Cancer is the leading cause of death worldwide. The current treatment options available for lung cancer are limited and have drawbacks such as poor bioavailability, numerous side effects, poor efficacy and drug resistance. 3D model serve as a novel approach for drug screening purposes and the evaluation of compounds in the platform can help identify potent compounds for further in vivo xenograft studies.

2012-09-06, Board Of Regents, Murray State University

Board of Regents Meeting Minutes

No abstract provided.

Case: Joined Cases C-58/10 To C-69/10, Monsanto Sas And Others, Sarah Nelson

Chicago-Kent Journal of International and Comparative Law

No abstract provided.

Functional Morphology Of Rat Hands And Feet: Correlation With The Ability To Grip Tree Branches During Locomotion, Jessica Elaine Fonce

Undergraduate Research Posters 2012

Anatomy and function are usually closely related. Since locomotion on tree branches is common among mammals, we expect to find that the anatomy is well adapted for gripping narrow cylindrical branch-like substrates. Based on the anatomy alone, rats are built for locomotion across cylindrical branches as well as terrestrial substrates.

Daily Eastern News: September 06, 2012, Eastern Illinois University

September

No abstract provided.

Scholarship Series: Ksu Faculty Showcase, Rob Cronin, Dane Philipsen, John Warren, Laura Najarian, Soohyun Yun, Mary Akerman, Karin Bliznik, Doug Lindsey, Jason Eklund, Tom Gibson, Bernard Flythe, Helen Kim, Charae Krueger, Robert Henry, Oral Moses, Judy Cole, Catherine Lynn, Allyson Fleck, John Lawless

Bailey School of Music Concert Programs

Kennesaw State University School of Music presents Faculty Showcase, a KSU School of Music Scholarship Series concert.

The Daily Egyptian, September 06, 2012, Daily Egyptian Staff

September 2012

No abstract provided.

Journal Usage Report For Fiscal Year 2012, Michael A. Cerbo Ii

Technical Services Reports and Statistics

Journal usage for the University Libraries are listed alphabetically by authority title. The report includes the usage statistics taken from each vendor and incorporated in Serials Solutions 360 Counter.

The report is broken down monthly for fiscal year 2012 and shows each journal's usage per month and the cost per use for the year, if available.

Rag1-/- Mutant Zebrafish Demonstrate Specific Protection Following Bacterial Re-Exposure., Claudia Hohn, Lora Petrie-Hanson

CVM Publications

BACKGROUND: Recombination activation gene 1 deficient (rag1(-/-)) mutant zebrafish have a reduced lymphocyte-like cell population that lacks functional B and T lymphocytes of the acquired immune system, but includes Natural Killer (NK)-like cells and Non-specific cytotoxic cells (NCC) of the innate immune system. The innate immune system is thought to lack the adaptive characteristics of an acquired immune system that provide enhanced protection to a second exposure of the same pathogen. It has been shown that NK cells have the ability to mediate adaptive immunity to chemical haptens and cytomegalovirus in murine models. In this study we evaluated the ability …

Oncostatin M Promotes Mammary Tumor Metastasis To Bone And Osteolytic Bone Degradation, Celeste Bolin, Ken Tawara, Caleb Sutherland, Jeff Redshaw, Patrick S. Aranda, Jim Moselhy, Robin Anderson, Cheryl Jorcyk

Biology Faculty Publications and Presentations

Oncostatin M (OSM) is an interleukin-6 (IL-6) family cytokine that has been implicated in a number of biological processes including inflammation, hematopoiesis, immune responses, development, and bone homeostasis. Recent evidence suggests that OSM may promote breast tumor invasion and metastasis. We investigated the role of OSM in the formation of bone metastases in vivo using the 4T1.2 mouse mammary tumor model in which OSM expression was knocked down using shRNA (4T1.2-OSM). 4T1.2-OSM cells were injected orthotopically into Balb/c mice, resulting in a greater than 97% decrease in spontaneous metastasis to bone compared to control cells. Intratibial injection of these same …

The Alestle - Vol. 65 No. 4 - 09/06/2012, Southern Illinois University Edwardsville

The Alestle

Vol. 65 No. 4

The Grizzly, September 6, 2012, Jessica Orbon, Sara Sherr, Larissa Coyne, Rosemary Clark, Austin Fox, Amanda Frekot, David Marino, Emerson Miles Hawkins, Alexa Lamontagne, Rayleen Rivera-Harbach, Michael Klazas, Courtney Scott, Kyu Chul Shin, Chris Rountree, Samantha Salomon, Jordan Demcher

Ursinus College Grizzly Newspaper, 1978 to Present

Ursinus Welcomes New Dean • Wismer Changes • Orientation Update • Dr. Heinzl Lecture • Gary Hodgson's Tenure as Campus Safety Officer • Meet Mike Mullin, New R.D. • Gender-Neutral Bathrooms Arrive on UC Campus • Residence Life Offers Support for the Class of 2016 • Opinion: Athletes Frustrated by Dining Changes; Senator Rubio Would Have Been a Better V.P. Choice for the GOP • Field Hockey Looks to Keep Tradition • Under New Coach, Volleyball Begins 2012 Season • Lofty Expectations for Bears Football

The Cyclase-Associated Protein Cap1 Is Important For Proper Regulation Of Infection-Related Morphogenesis In Magnaporthe Oryzae., Xiaoying Zhou, Haifeng Zhang, Guotian Li, Brian Shaw, Jin-Rong Xu

Department of Botany and Plant Pathology Faculty Publications

Surface recognition and penetration are critical steps in the infection cycle of many plant pathogenic fungi. In Magnaporthe oryzae, cAMP signaling is involved in surface recognition and pathogenesis. Deletion of the MAC1 adenylate cyclase gene affected appressorium formation and plant infection. In this study, we used the affinity purification approach to identify proteins that are associated with Mac1 in vivo. One of the Mac1-interacting proteins is the adenylate cyclase-associated protein named Cap1. CAP genes are well-conserved in phytopathogenic fungi but none of them have been functionally characterized. Deletion of CAP1 blocked the effects of a dominant RAS2 allele …

Knotts Landing, Unh Communications And Public Affairs

UNH Today Archive

No abstract provided.

Self-Love And Self-Respect In The Meaningful Life, Erica Stonestreet

Forum Lectures

Most people have the sense that there's something wrong with living a meaningless life. Since most meaningless lives seem morally blameless, however, it's not obvious exactly what is wrong with it. Starting with a plausible conception of a meaningful life as a life engaged with values beyond oneself, I suggest that the problem is that someone living outside of this conception is not according herself a kind of recognition she deserves as a human being. Comparing self-respect and self-love as candidates for this recognition, I argue that lacking self-love is actually the more fitting explanation for what goes wrong in …