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2011

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Hiv-1 Tat Protein Promotes Neuronal Dysfunction Through Disruption Of Micrornas, J Robert Chang, Ruma Mukerjee, Asen Bagashev, Luis Del Valle, Tinatin Chabrashvili, Brian J. Hawkins, Johnny J. He, Bassel E. Sawaya Nov 2011

Hiv-1 Tat Protein Promotes Neuronal Dysfunction Through Disruption Of Micrornas, J Robert Chang, Ruma Mukerjee, Asen Bagashev, Luis Del Valle, Tinatin Chabrashvili, Brian J. Hawkins, Johnny J. He, Bassel E. Sawaya

School of Medicine Faculty Publications

Over the last decade, small noncoding RNA molecules such as microRNAs (miRNAs) have emerged as critical regulators in the expression and function of eukaryotic genomes. It has been suggested that viral infections and neurological disease outcome may also be shaped by the influence of small RNAs. This has prompted us to suggest that HIV infection alters the endogenous miRNA expression patterns, thereby contributing to neuronal deregulation and AIDS dementia. Therefore, using primary cultures and neuronal cell lines, we examined the impact of a viral protein (HIV-1 Tat) on the expression of miRNAs due to its characteristic features such as release …

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Combination Of Depot Medroxy Progesterone Acetate And Javanese Long Pepper Extract On Body Weight, Hematology, And Blood Biochemistry As A Safe Contraception Model, Yurnadi Yurnadi, Yoel Asmida, Dwi Anita Suryandari, Nukman Moeloek Nov 2011

Combination Of Depot Medroxy Progesterone Acetate And Javanese Long Pepper Extract On Body Weight, Hematology, And Blood Biochemistry As A Safe Contraception Model, Yurnadi Yurnadi, Yoel Asmida, Dwi Anita Suryandari, Nukman Moeloek

Makara Journal of Science

The development of male hormonal contraception is based on a decrease in sperm concentration without affecting libido and sexual potency. The combination of depot medroxy progesterone acetate (DMPA) + extract of Javanese long pepper (JLP) with dosages of 0.94 mg and 1.88 mg decreases the concentration of spermatozoa. However, it remains unknown whether the combination influences body weight, hematology, and blood biochemistry. Therefore, it is necessary to investigate the effect of DMPA + JLP extracts on the body weight, hematology, and blood biochemistry of male rats (Rattusnorvegicus L.) using Sprague-Dawley strains. The research uses a completely randomized design (CRD); one …

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Dietary Food Fortified With Orotic Acid And Liver Function, Yohanes Buang Nov 2011

Dietary Food Fortified With Orotic Acid And Liver Function, Yohanes Buang

Makara Journal of Science

The effects of dietary food fortified with orotic acid (1.0%) on liver function were studied in rats. The rats fed with orotic acid promoted liver triglyceride content markedly, that was 5-fold higher than that of the control. The liver malondialdehyde (MDA) content increased by 10%, but the gluthation peroxidase (GSH-Px) activity decreased by 50%. The serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) activities increased by 25% and 30%, respectively. Therefore, the decreased GSH-Px activity was associated with the promotions of AST, ALT, and the liver MDA levels. In conclusion: dietary orotic acid promotes lipid peroxidation but reduces the rate …

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Solvent Extraction Of Ginger Oleoresin Using Ultrasound, Muhammad Dani Supardan, Anwar Fuadi, Pocut Nurul Alam, Normalina Arpi Nov 2011

Solvent Extraction Of Ginger Oleoresin Using Ultrasound, Muhammad Dani Supardan, Anwar Fuadi, Pocut Nurul Alam, Normalina Arpi

Makara Journal of Science

The use of ultrasound in extraction process creates novel and interesting methodologies, which are often complementary to conventional extraction methods. In the present study, the use of ultrasound to extract oleoresin from ginger (Zingiber officinale R.) was investigated. The extraction was performed by using ethanol as solvent in the presence of ultrasonic irradiations operating at frequency of 42 kHz at extraction temperature of 60 o C. The oleoresin extracted was in the form of dark thick liquid with specific ginger flavor. Based on GC-MS analysis, the use of ultrasound was not give an effect on alteration of main component in …

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Williams, Pirates Run Past Mavericks, 90-85, Armstrong State University Collections, Armstrong Athletics, Armstrong Men's Basketball Archives, Armstrong Men's Basketball News Archives Nov 2011

Williams, Pirates Run Past Mavericks, 90-85, Armstrong State University Collections, Armstrong Athletics, Armstrong Men's Basketball Archives, Armstrong Men's Basketball News Archives

Armstrong Athletics: Men's Basketball News (Archived)

No abstract provided.

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Secondary Metabolite Of Aspergillus Fumigatus, Endophytic Fungi Of The Medicinal Plant Garcinia Griffithii, Elfita Elfita, Muharni Muharni, Tri Indah Nov 2011

Secondary Metabolite Of Aspergillus Fumigatus, Endophytic Fungi Of The Medicinal Plant Garcinia Griffithii, Elfita Elfita, Muharni Muharni, Tri Indah

Makara Journal of Science

No abstract provided.

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Cloning Of Dengue Virus Type 3 (Indonesian Strain D3-1703) Non Structural-1 Gene Into Pyes2/Ct Vector, Vanny Narita, Rahma Micho Widyanto, Sabar Pambudi, Tjahjani Tjahjani Sudiro Nov 2011

Cloning Of Dengue Virus Type 3 (Indonesian Strain D3-1703) Non Structural-1 Gene Into Pyes2/Ct Vector, Vanny Narita, Rahma Micho Widyanto, Sabar Pambudi, Tjahjani Tjahjani Sudiro

Makara Journal of Science

Dengue is an infectious disease caused by dengue virus. Dengue endemic region includes America, Western Pacific, Africa, East Mediterranian, and South East Asia including Indonesia. An early diagnostic system specific for Indonesia is needed to control dengue in Indonesia. In this research, cloning of Non Structural 1 (NS1) gene from dengue virus type 3 (Indonesian strain D3-1703) into pYES2/CT vector was performed. In the long run, NS1 recombinant protein will be expressed in Saccharomyces cerevisiae for diagnostic materials. Polymerase Chain Reaction (PCR) amplification of NS1 gene fragments were done with optimal annealing temperature at 55 ºC. NS1 gene fragment and …

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The Free Radical Scavenging And Anti-Hyperglycemic Activities Of Various Gambiers Available In Indonesian Market, Galuh Widiyarti, Andini Sundowo, Muhammad Hanafi Nov 2011

The Free Radical Scavenging And Anti-Hyperglycemic Activities Of Various Gambiers Available In Indonesian Market, Galuh Widiyarti, Andini Sundowo, Muhammad Hanafi

Makara Journal of Science

No abstract provided.

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Preparation And Characterization Of Co-Processed Excipient Carrageenan-Pregelatinized Cassava Starch Propionate As A Matrix In The Gastroretentive Dosage, Effionora Anwar, Engkom Komariah, Junaedi Junaedi Nov 2011

Preparation And Characterization Of Co-Processed Excipient Carrageenan-Pregelatinized Cassava Starch Propionate As A Matrix In The Gastroretentive Dosage, Effionora Anwar, Engkom Komariah, Junaedi Junaedi

Makara Journal of Science

No abstract provided.

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Band Alignment Of Ultrathin Gizo/Sio2/Si Heterostructure Determined By Electron Spectroscopy, Dahlang Tahir, Sri Dewi Astuty Ilyas, Hee Jae Kang Nov 2011

Band Alignment Of Ultrathin Gizo/Sio2/Si Heterostructure Determined By Electron Spectroscopy, Dahlang Tahir, Sri Dewi Astuty Ilyas, Hee Jae Kang

Makara Journal of Science

Amorphous GaInZnO (GIZO) thin films are grown on SiO2/Si substrate by the RF magnetron sputtering method. By the combination of measured band gaps from reflection energy loss spectroscopy (REELS) spectra and valence band from X-ray photo-electron spectroscopy (XPS) spectra, we have demonstrated the energy band alignment of GIZO thin films. The band gap values are 3.2 eV, 3.2 eV, 3.4eV and 3.6eV for the concentration ratios of Ga: In: Zn in GIZO thin films are 1:1:1, 2:2:1, 3:2:1 and 4:2:1, respectively. These are attributed to the larger band gap energy of Ga2O3 compared with In2O3 and ZnO. The valence band …

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Synthesizing Derivatives From Cyclopentanone Analogue Curcumin And Their Toxic, Antioxidant And Anti-Inflammatory Activities, Yum Eryanti, Yuana Nurulita, Rudi Hendra, Yuharmen Yuharmen, Jufrizal Syahri, Adel Zamri Nov 2011

Synthesizing Derivatives From Cyclopentanone Analogue Curcumin And Their Toxic, Antioxidant And Anti-Inflammatory Activities, Yum Eryanti, Yuana Nurulita, Rudi Hendra, Yuharmen Yuharmen, Jufrizal Syahri, Adel Zamri

Makara Journal of Science

Three types of cyclopentanone derivatives have been synthesized from aromatic aldehyde and ketone derivatives under a base condition through aldol condensation. These cyclopentanone products were 2,5-dibenzylidene-cyclopentanone (a), 2,5-bis-(4-hydroxy-benzylidene)-cyclopentanone (b), and 2,5-bis-(4-hydroxy-benzylidene)-cyclopentanone (c) which has a yield of 63-99%. The chemical structure of these compounds were determined using UV, IR and NMR spectroscopy. In order to clarify the role of hydroxyl and amine moieties, toxic, antioxidant and anti-inflammatory activities were carried out. The toxic test indicated that the compounds showed strong toxicity. In addition, the presence of hydroxyl and amine groups on both rings of curcumin increased the antioxidant and anti-inflammatory …

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Isolation, Cloning And Characterization Of Actin-Encoding Cdnas From Jatropha Curcas L. Ip-2p, Ratna Yuniati, Utut Widyastuti, Didy Sopandie, Akiho Yokota, Kinya Akashi, Suharsono Suharsono Nov 2011

Isolation, Cloning And Characterization Of Actin-Encoding Cdnas From Jatropha Curcas L. Ip-2p, Ratna Yuniati, Utut Widyastuti, Didy Sopandie, Akiho Yokota, Kinya Akashi, Suharsono Suharsono

Makara Journal of Science

Actin is a major component of the plant cytoskeleton, so all cells contain this protein. Actin is expressed constitutively and is involved in basic housekeeping functions required for cell maintenance. Because of this, it has been frequently used as an internal control to normalize changes in gene expressions analysis. Actually, the information of nucleotide sequence of actin gene of Jatropha curcas L. population IP-2P from Indonesia is not available yet. The objective of this research was to isolate, clone and characterize cDNA of actin genes of J. curcas IP-2P. Three partial actin gene sequences had been successfully isolated by PCR …

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Heterocyclic Synthesis Using Nitrilimines: Part 18. Synthesis Of New Fused Heterocycles Containing Triazinone Moiety, Hany Mahmod Dalloul Nov 2011

Heterocyclic Synthesis Using Nitrilimines: Part 18. Synthesis Of New Fused Heterocycles Containing Triazinone Moiety, Hany Mahmod Dalloul

Makara Journal of Science

A series of new 4,5-dihydro-6-oxo-1,2,4-triazino[4,5-b]1,2,3,4-tetrahydro-β-carbolines were synthesized by the reaction of methyl 1,2,3,4-tetrahydro-β-carboline-3-carboxylate and the appropriate hydrazonoyl halide in presence of triethylamine. The structures of the title compounds have been established by their elemental analyses and spectroscopecal data. The microbial features of some of the synthesized compounds were studied by a known method

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Terpenoids From The Stem Bark Of Jatropha Plants And Their Biological Activities, Sahidin Sahidin, Ardiansyah Ardiansyah, Taher Muhammad, Manggau Marianti Nov 2011

Terpenoids From The Stem Bark Of Jatropha Plants And Their Biological Activities, Sahidin Sahidin, Ardiansyah Ardiansyah, Taher Muhammad, Manggau Marianti

Makara Journal of Science

Three terpenoids, including two diterpenes (curcusone B and jatrophone) and a triterpene (stigmasterol) have been isolated from the stem bark of Jatropha plants. Curcusone B and stigmasterol were isolated from J. curcas, meanwhile jatrophone and stigmasterol were from J. gossypifolia. The biological activities of these compounds have been evaluated toward bacteria, fungi and tumour cells. Isolation was carried out in vacuum liqiud cromatography (VLC) technique with silica gel as an adsorben and some solvents as eluents. The compound structures were determined by spectroscopic methodes i.e. UV-vis, FTIR, NMR (1-D, 2-D) and were then compared based on their spectroscopic data with …

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Correction Of The Ground State Energy Of One-Dimensional Gross-Pitaevskii Equation With Gain-Loss Term, Teguh Budi Prayitno Nov 2011

Correction Of The Ground State Energy Of One-Dimensional Gross-Pitaevskii Equation With Gain-Loss Term, Teguh Budi Prayitno

Makara Journal of Science

We consider the correction of ground state energy of one-dimensional Gross-Pitaevskii equation by adding a gain-loss term as a time-dependent external potential. The interesting purpose of this term is that it can be used to explain the experimental results especially in the nonlinear fiber optics regarding the pulse propagation and collapse-revival of the condensate in the Bose-Einstein condensation. In the Bose-Einstein condensation itself, the function can represent that condensate can interact with the normal atomic cloud. Some analytical solutions have been obtained by choosing an ansatz solution of the wave function and its solution can be dark or bright soliton. …

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Preparation, Characterization And Catalytic Activity Of Cuo/Ts-1 On Benzene Hydroxylation Reaction, Ratna Ediati, Hamzah Fansuri, Didik Prasetyoko Nov 2011

Preparation, Characterization And Catalytic Activity Of Cuo/Ts-1 On Benzene Hydroxylation Reaction, Ratna Ediati, Hamzah Fansuri, Didik Prasetyoko

Makara Journal of Science

CuO/TS-1 catalysts have been prepared and tested in the benzene hydroxylation. TS-1 was synthesized by hydrothermal method, while CuO/TS-1 was prepared by impregnation method using Cu(NO)2.3H2O as precursor. Catalysts were characterized by using X-ray diffraction (XRD), infrared spectroscopy (IR), and N2 adsorption-desorption techniques. The catalytic activity was tested in the hydroxylation reaction of benzene. The products were analyzed using gas chromatography. Catalyst characterization by XRD and IR techniques have showed that the catalyst structure was a MFI type of zeolite. XRD pattern have showed the orthorombic structure and indicated the presence of CuO aggregation. The results of the pyridine adsorption …

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Serosurveillance Of Avian Influenza Virus Subtype H5n1 With Haemagglutination-Inhibition On Wild Aquatic Birds In Pulau Dua Serang Natural Reserves, Banten Province, Dewi Elfidasari, Dedy Duryadi Solihin, Retno Damayanti Soejoedono, Sri Murtini, Yus Rusila Noor Nov 2011

Serosurveillance Of Avian Influenza Virus Subtype H5n1 With Haemagglutination-Inhibition On Wild Aquatic Birds In Pulau Dua Serang Natural Reserves, Banten Province, Dewi Elfidasari, Dedy Duryadi Solihin, Retno Damayanti Soejoedono, Sri Murtini, Yus Rusila Noor

Makara Journal of Science

Further detailed research is required to obtain deeper information on the role of wild birds on the distribution of Avian influenza in Asia. A research has been carried out on February–June 2007 focused on blood sampling (serosurveillance) of wild birds in Pulau Dua Nature Reserves (CAPD), Serang, Banten. The research is aimed to investigate the infection of AI virus sub-tye H5N1 on the studied wild birds. The blood samples were taken from studied aquatic birds, followed by HI (haemagglutination-inhibition) test. A total of 183 samples represent 7 water bird species were taken i.e Cattle egret Bubulcus ibis, Javan pond-heron Ardeola …

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Effects Of Neutrino Electromagnetic Form Factors On Neutrino Interaction With Finite Temperature Electron Matter, Listiana Satiawati, Anto Sulaksono Nov 2011

Effects Of Neutrino Electromagnetic Form Factors On Neutrino Interaction With Finite Temperature Electron Matter, Listiana Satiawati, Anto Sulaksono

Makara Journal of Science

The differential cross-section of neutrino interaction with dense and warm electron gasses has been calculated by taking into account the neutrino electromagnetic form factors. The significant effect of electromagnetic properties of neutrino can be found if the neutrino dipole moment, μ ν , is ≥ 5.10-9 μB and neutrino charge radius, Rv, is ≥ 5.10-6 MeV-1. The importance of the retarded correction, detailed balance and Pauli blocking factors is shown and analyzed. Many-body effects on the target matter which are included via random phase approximation (RPA) correlation as well as photon effective mass are also investigated.

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Senior Figures In Education Echo Hunt's View That There Is No Case For More Universities, Technological Or Otherwise, Irish Times Nov 2011

Senior Figures In Education Echo Hunt's View That There Is No Case For More Universities, Technological Or Otherwise, Irish Times

Media

No abstract provided.

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Standard Furniture, Adam Rogers Nov 2011

Standard Furniture, Adam Rogers

Theses

I seek simplicity through my intention to establish a particular beauty, a certain calm achieved both visually and through the intangible feel of my furniture - itself simply a reservoir for the collection and ordering of possessions. The result will reflect the balance between the order inherent in the modest furniture forms that follow function and the emphasized personal quality of certain components of the whole. Through exercising restraint in form, the central element is emphasized, thereby omitting the unimportant to magnify the important. I chase an elusive beauty and an ethereal quality in my furniture. I intend to explore …

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The Demographic Context Of Social Diversity And The Integration Of Canada's New Second Generation, Feng Hou Nov 2011

The Demographic Context Of Social Diversity And The Integration Of Canada's New Second Generation, Feng Hou

Migration and Ethnic Relations Colloquium Series

No abstract provided.

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Dit Grangegorman Hearings Open, Tim O'Brien Nov 2011

Dit Grangegorman Hearings Open, Tim O'Brien

Media

No abstract provided.

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November 24, 2011: Happy Secular Thanksgiving, Bruce Ledewitz Nov 2011

November 24, 2011: Happy Secular Thanksgiving, Bruce Ledewitz

Hallowed Secularism

Blog post, “Happy Secular Thanksgiving“ discusses politics, theology and the law in relation to religion and public life in the democratic United States of America.

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Chanticleer | Vol 60, Issue 11, Jacksonville State University Nov 2011

Chanticleer | Vol 60, Issue 11, Jacksonville State University

Chanticleer

No abstract provided.

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11/24/2011 Obituary Records, Hawaii Obituaries Nov 2011

11/24/2011 Obituary Records, Hawaii Obituaries

Obituaries

List of Obituaries for individuals who passed away on 11/24/2011. Scroll down to see the names and obituary description.

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Evaluation Of Academic Competencies Through Standardized Instruments, Oscar Garcia López, Gema Santiago Gómez, Sara Redondo Duarte Nov 2011

Evaluation Of Academic Competencies Through Standardized Instruments, Oscar Garcia López, Gema Santiago Gómez, Sara Redondo Duarte

Higher Learning Research Communications

The aim of this investigation is to assess the correlation among different competencies-assessment systems available on the market to measure social skills in the university environment. In order to carry out the research, three self-perception competency tests were used, and 30 competencies were evaluated in a Likert scale with several response levels: the LPA-Q, the ESCI-U, and the CompeUEM. The three questionnaires were completed by 57 university students. The results show a low degree of agreement among the different questionnaires in relation to measuring the same competencies, as well as an unclear factor structure.

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The Weekly Challenger, November 24, 2011, The Weekly Challenger, Et Al Nov 2011

The Weekly Challenger, November 24, 2011, The Weekly Challenger, Et Al

Weekly Challenger Newspaper Collection

The November 24, 2011, issue of The Weekly Challenger.

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Forever Free: The Dakota People's Civil War, John M. Rudy Nov 2011

Forever Free: The Dakota People's Civil War, John M. Rudy

Interpreting the Civil War: Connecting the Civil War to the American Public

As I mentioned last week, I left Fort Snelling after our tour as part of the National Association for Interpretation annual conference unfulfilled. The potential for high-drama and deeply meaningful connections was palpable on that landscape. The audience, a crowd of interpreters, were begging for meanings. One African American woman in the group, after the site administrator mentioned in passing Dred and Harriet Scott being held at the site, asked about the nature of the labor used to build the fort. I was sitting in the row behind her. I could not see her face. But from the inflection in …

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Thanksgiving, Richard C. Crepeau Nov 2011

Thanksgiving, Richard C. Crepeau

On Sport and Society

(As with all American traditions if it happened once or twice it is one. Therefore I present my traditional Thanksgiving piece) The History of Thanksgiving and of Football both go back into the Middle Ages, and so it may not be so strange that the two would become intertwined in modern America.

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Public Hearing Transcripts - Eastern - Makindu - Rtjrc24.11 (St Peter's Catholic Church Hall Makindu), Truth, Justice, And Reconciliation Commission Nov 2011

Public Hearing Transcripts - Eastern - Makindu - Rtjrc24.11 (St Peter's Catholic Church Hall Makindu), Truth, Justice, And Reconciliation Commission

I. Core TJRC Related Documents

No abstract provided.

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