Digital Commons Network^™

Interview With Kelly Hunt Persky, Kelly Hunt Persky

Oral Histories

No abstract provided.

Interview With Oscar Monj, Oscar Monj

Oral Histories

No abstract provided.

Nitrogen Loss In A Barrier Island Shallow Aquifer System, Caitlin Young, Fang Liu

Long Island Geologists' Abstracts

Titles and Abstracts for the Confernence on "Geology of Long Island and Metropolitan New York,Long Island Geologists is a program of the Department of Geosciences at Stony Brook University. Each year, the activities include one or two field trips and, on a Saturday in April, a conference on the "Geology of Long Island and Metropolitan New York." Teachers and professional geologists can receive in-service credit for participating in these events. The abstracts contained within this collection are digital representations or copies of papers presented over the years at various conferences. For additional information on a particular topic or paper, contact …

The Mineralogy And Metal Contamination Of Sediments In The Apex Of The New York Bight, Ny, Usa: An Integrated Laboratory And Field Study Of Trace Metal Behavior In An Urban Estuary, Noureddin Amaach

Long Island Geologists' Abstracts

Titles and Abstracts for the Confernence on "Geology of Long Island and Metropolitan New York, Additional information on the Long Island Geologists may be found at: http://pbisotopes.ess.sunysb.edu/lig/. Information on the Long Island Association of Professional Geologists may be found at: www.liapg.org. | Long Island Geologists is a program of the Department of Geosciences at Stony Brook University. Each year, the activities include one or two field trips and, on a Saturday in April, a conference on the "Geology of Long Island and Metropolitan New York." Teachers and professional geologists can receive in-service credit for participating in these events. The abstracts …

Quantitative Reappraisal Of The Helmholtz-Guyton Resonance Theory Of Frequency Tuning In The Cochlea, Charles F. Babbs

Weldon School of Biomedical Engineering Faculty Publications

To explore the fundamental biomechanics of sound frequency transduction in the cochlea, a two-dimensional analytical model of the basilar membrane was constructed from first principles. Quantitative analysis showed that axial forces along the membrane are negligible, condensing the problem to a set of ordered one-dimensional models in the radial dimension, for which all parameters can be specified from experimental data. Solutions of the radial models for asymmetrical boundary conditions produce realistic deformation patterns. The resulting second-order differential equations, based on the original concepts of Helmholtz and Guyton, and including viscoelastic restoring forces, predict a frequency map and amplitudes of deflections …

Making Connections Between Science And Equity: A Motivation To Teach Science In Elementary Grades, Grinell Smith, Colette Rabin

Faculty Publications

Teacher quality is among the strongest correlates of student outcomes. However, only about a quarter of the nation’s elementary teachers consider themselves qualified to teach science. In this descriptive and exploratory study, we investigated whether helping pre-service teacher candidates explore connections between science and issues of equity, particularly around sustainability issues, could help them see the importance of teaching science to their students more often. Qualitative and quantitative data were collected from 59 students enrolled in revised science methods courses at a large public university. Our findings suggest that positioning science instruction thusly was perceived as a strong motivator to …

Phylogeographic Analysis Of The Bushy Seaside Tansy (Borrichia Frutescens) Along The Coast Of Florida, Christopher S. Thaver, Aaron Schrey, Christina Richards

9th Annual Undergraduate Research Symposium and Celebration

I investigated phylogeography of Borrichia frutescens (bushy seaside tansy) in Florida. Phylogeography is the study of the geographic distribution of the genealogy of individuals. It is used to help understand how the changes in the landscape shaped the populations’ gene pool. Borrichia frutescens is a coastal salt marsh plant which occurs in Florida. I isolated a segment of the chloroplast DNA (cpDNA) in Borrichia frutescens. First, I obtained Borrichia frutescens from multiple locations in Florida. Next, I extracted DNA from leaves and perform a polymerase chain reaction (PCR) to amplify a segment of cpDNA; I will then determine the DNA …

Inducible Expression Of Cancer Testis Antigens Following Treatment With A Dna Methylation Inhibitor, Tyler J. Farnum

9th Annual Undergraduate Research Symposium and Celebration

Background: Critical to the success of cancer immunotherapies is the identification of appropriate target antigens. Cancer-testis antigens (CTAs) are ectopically expressed immunoprivileged antigens transcriptionally controlled by DNA methylation which have utility as immunotherapeutic targets. 5-azacytidine, an analogue of cytidine, has been shown to induce expression of CTAs in cancer. During the experiment, we analyzed matched samples from 42 myelodysplastic syndrome patients receiving an oral regimen of 5-azacytidine to determine if an anti-CTA immune response was generated.

Methods: Immunoglobulin G (IgG) responses to a panel of 29 CTAs including NY-ESO1, Mage-1, and SSX2 were analyzed by ELISA, Western Blot, and SEREX …

Development Of 1,2,3,4-Tetrahydroacridin-9(10h)-Ones As Potential Inhibitors Of P.Falciparum Isolates Tm90-C2b & W2 Via Structure Activity Relationship (Sar) Studies, Lisa Luong

9th Annual Undergraduate Research Symposium and Celebration

Malaria exceeds 200 million annual cases worldwide due to increasing parasitic resistance to commonly available antimalarial drugs such as atovaquone. The objective of this research is to prepare 1,2,3,4-tetrahydroacridin-9(10H)-one(THA) derivatives (by utilizing structure-activity relationship (SAR) studies of the benzenoid ring of the THA scaffold) to test for activity against P. falciparum isolates TM90-C2B (an atovaquone-resistant strain) and W2 (an atovaquone-susceptible strain).  Synthesis of THAs involves refluxing substituted anthranilic acids in phosphorus oxychloride (POCl₃) with cycloalkanones to form various 9-chloro-1,2,3,4-tetrahydroacridines. Subsequent hydrolysis in acetic acid yields the respective THA. When compounds were screened in vitro against blood stages …

Sex Differences In Adolescent Male And Female Rats Influence Changes In Non-Spatial Learning And Working Memory Following Binge-Ethanol Treatment, Jancy Mathew

9th Annual Undergraduate Research Symposium and Celebration

ABSTRACT

Binge alcohol use is of primary concern in humans; given this is the most common form of alcohol consumption among this age group, which has been associated with similar patterns of alcohol use in early adulthood.  Male and female adolescents report similar levels of alcohol consumption during early adolescence.  In animal models, excessive ethanol has been correlated with inhibition and decreased activity within the hippocampus. The hippocampus plays a primary role in the formation of short-term memory, cognition, and learning. These impairments are most debilitating during adolescence in which the brain undergoes rapid and substantial developmental changes. The present …

Applications Of Mathematics To Biology: Using Combinatorial Models To Understand Dna Rearrangements In Ciliates, Mary Ellen Billington

9th Annual Undergraduate Research Symposium and Celebration

Ciliates are small eukaryotic organisms that perform extensive genomic rearrangements during development, including recombination, inversion, and excision of certain genetic sequences. The mechanisms by which ciliates perform these extensive chromosomal recombination events are of great interest to both biologists and mathematicians. Understanding the sophisticated mechanisms performed in this model organism may provide insights into other epigenetic processes. Many ciliate genes have been sequenced, and it is now important to examine the possible pathways that result in correctly rearranged genes. Because ciliates perform extensive rearrangements under temporal and spatial constraints, it is likely that many recombination steps are performed simultaneously. So, …

Mk-801 Administration In Adolescent Male Rats And Cocaine Conditioned Place Preference, Stephanie Willis

9th Annual Undergraduate Research Symposium and Celebration

The present experiment is extends work from Badanich and colleagues (2006), and Brown (2008). Sprague-Dawley rats can be conditioned with 20 mg/kg cocaine, meaning rats will pair cues, with the physical effects of cocaine. By associating cues with the physical effects of cocaine, the rats seek out these cues to recapture the physical effects of cocaine. Brown (2008) examined the impact of 0.2 mg/kg MK-801, a glutamatergic N-methyl-D-aspartate (NMDA) receptor antagonist, on conditioned place preference (CPP) in adult male rats.  Mk-801 blocks the NMDA receptor from releasing glutamate, and in turn blocks drug-associated memories. This experiment investigates the effects of …

Entre Nous. A Critical Appraisal Of Science Outcomes Of Schooling For African American Children And Youth Enrolled In The Houston Independent School District, James A. Johnson Ph.D., Bernell M. Peltier-Glaze Ph.D., Danita Bailey-Perry Ph.D.

The Bridge: Interdisciplinary Perspectives on Legal & Social Policy

No abstract provided.

Role Of Mechanical Strain On The Cardiomyogenic Differentiation Of Periodontal Ligament Derived Stem Cells, Daniel Pelaez

Open Access Dissertations

The application of cellular therapies for the treatment of myocardial infarction has provided encouraging evidence for the possibility of cellular therapies to restore normal heart function. However, questions still remain as to the optimal cell source, pre-conditioning methods and delivery techniques for such an application. Here I propose the use of a unique population of stem cells arising from the embryonic neural crest. These cells were shown to express neural crest markers as well as pluripotency-associated markers. Furthermore, the cells were shown to express proteins essential to the formation of gap junctions and to possess a cardiomyogenic differentiation potential by …

Truman State University Professor Talks About Scarce Resources And Unlimited Desires On April 11, Winthrop University

Winthrop News 2011

• Hoeschele's latest book, “The Economics of Abundance: A Political Economy of Freedom, Equity and Sustainability,” examines the assumptions of scarce resources, unlimited desires and maximized consumption in a variety of innovative and creative ways.

Targeted Minimum Loss Based Estimator That Outperforms A Given Estimator, Susan Gruber, Mark J. Van Der Laan

U.C. Berkeley Division of Biostatistics Working Paper Series

Targeted minimum loss based estimation (TMLE) provides a template for the construction of semiparametric locally efficient double robust substitution estimators of the target parameter of the data generating distribution in a semiparametric censored data or causal inference model (van der Laan and Rubin (2006),van der Laan (2008), van der Laan and Rose (2011)). In this article we demonstrate how to construct a TMLE that also satisfies the property that it is at least as efficient as a user supplied asymptotically linear estimator. For the sake of illustration we focus on estimation of the additive average causal effect of a point …

The Tiger Vol. 105 Issue 10 2011-04-08, Clemson University

Tiger Newspapers

No abstract provided.

Literary Genesis, Stephanie Wood '11

Honor Scholar Theses

No abstract provided.

The Utah Statesman, April 8, 2011, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

Uab Launches Drug Trial Aimed At Triple-Negative Breast Cancers, Staff

Browse All News

No abstract provided.

Sensory Modulation Disorder And Schizophrenia: Linking Behavioral Measures, Linda Olson

Theses and Dissertations

Schizophrenia is a devastating disorder affecting millions of people in the United States. Studies leading to new understanding of and intervention for this disorder are essential, as current interventions are minimally effective. The end result is high rates of re-hospitalization, impaired occupational performance and decreased community reintegration. According to the Diagnostic and Statistical Manual of Mental Disorders, symptoms of schizophrenia are categorized as positive or negative, with both types of symptoms impacting successful occupational engagement. Based on behavioral observations occupational therapists have hypothesized that this population may also experience sensory modulation disorder (SMD). Although electrophysiological studies support the presence of …

Uab Biology Student Awarded Knauss Fellowship, Jim Bakken

Browse All News

No abstract provided.

King Crabs Invade Antarctica, Could Jeopardize Cures For Disease, Jim Bakken

Browse All News

No abstract provided.

Epignetics And Allergic Disease, Jacob Sweeney '11

Honor Scholar Theses

In this thesis I will propose a novel framework for understanding allergy. I will argue that exposure to certain early-life environments lead to life-long allergic disease through epigenetic mechanisms. Although my argument currently exists as an unsubstantiated hypothesis, I will review indirect evidence that I have gathered throughout the immunologic and epigenetic literature to support my claim. | will then propose a set of experiments which will test my hypothesis. This thesis will address current scientific “hot topics” and their implications will challenge fundamental tenants of biology. Rather than jumping straight into the argument I will begin with some background …

Daily Eastern News: April 08, 2011, Eastern Illinois University

April

No abstract provided.

Leading Innovation: Creating A Culture Of Sustainability Workbook, Connie I. Reimers-Hild

Kimmel Education and Research Center: Faculty and Staff Publications

A workbook designed to compliment the workshop, "Leading Innovation:  Creating a Culture of Sustainability" and focused on teaching Dr. Connie's 5 Rays of Innovation

Avian Community Ecology And The Shifting Baseline In Sugarcreek Metropark, Jennifer Lynne Hays, Thomas P. Rooney, Jeffrey L. Peters

Biological Sciences Faculty Publications

No abstract provided.

Abundance And Trends Of Woodpecker Populations In The Wright State Biology Preserve, Brittany Damron, Thomas P. Rooney

Biological Sciences Faculty Publications

No abstract provided.

Carbon Sequestration In Soils Of The Wright State University Biology Preserve, Laurie Wissler, Thomas P. Rooney

Biological Sciences Faculty Publications

No abstract provided.

Wright State University Celebration Of Research, Scholarship And Creative Activities Book Of Abstracts Friday, April 8, 2011, Wright State University Office Of Undergraduate Research And Stemm Activities

Celebration of Undergraduate & Graduate Research, Scholarship, and Creative Activities Materials

The student abstract booklet is a compilation of abstracts from students' oral and poster presentations at Wright State University's second annual Celebration of Research, Scholarship and Creative Activities on April 8, 2011.