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Translocation Effects Of Lcrv Extracellular Surface Residues And Regulation Of Lcrg Binding To The T3ss Of Yersinia Pestis, Thomas A. Henderson

Theses and Dissertations

Yersinia pestis, the etiological agent of the plague, immobilizes the host's innate immune response by translocating proteins called Yops (Yersinia outer proteins) into the eukaryotic cytoplasm using a type III secretion system (T3SS) injectisome known as the Yersinia secretion complex (Ysc). The T3SS injectisome, in many ways, resembles a hypodermic needle, composed of oligomeric rings with distinct areas responsible for different functions and many of these areas share homology to the flagellar T3SS basal body inner and outer membrane rings. Starting with the cytoplasmic region of the inner membrane known as the C-ring, this is an area where secretion is …

Screening Synteny Blocks In Pairwise Genome Comparisons Through Integer Programming, Haibao Tang, Eric Lyons, Brent S. Pedersen, James C. Schnable, Andrew H. Paterson, Michael Freeling

Department of Agronomy and Horticulture: Faculty Publications

Background:

It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor. Analyses are particularly problematic among lineages that have repeatedly experienced whole genome duplication (WGD) events. To compare multiple “subgenomes” derived from genome duplications, we need to relax the traditional requirements of “one-to-one” syntenic matchings of genomic regions in order to reflect “one-to-many” or more generally “many-to-many” matchings. However this relaxation may result in the identification of synteny blocks that are derived from ancient shared WGDs that are not of interest. For many downstream analyses, we …

Congenital Bone Marrow Failure In Dna-Pkcs Mutant Mice Associated With Deficiencies In Dna Repair, Shichuan Zhang, Hirohiko Yajima, Hoangdinh Huynh, Junke Zheng, Elsa Callen, Hua-Tang Chen, Nancy Wong, Samuel Bunting, Yu-Fen Lin, Mengxia Li, Kyung-Jone Lee, Michael Story, Eric Gapud, Barry P. Sleckman, André Nussenzweig, Cheng Cheng Zhang, David J. Chen, Benjamin P.C. Chen

Open Access Publications

No abstract provided.

Gas Embolic Factors In Cardiovascular Health, Eric L. Cutler

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Gas emboli are a clinical issue often encountered in the space exploration, marine construction, and medical fields.  Individuals involved with these disciplines will often have asympomatic gas emboli circulating throughout their bodies on a regular basis.  A study into the impact of chronic asymptomatic gas emboli on the risk of atherosclerosis in humans is thus presented.  This research utilized a custom built cardiovascular flow simulator and accompanying data acquisition system to experimentally determine the influence of gas emboli under varied circumstances on the mean wall shear stress of a tube in-vitro.  A directly inverse relationship between gas embolus presence in …

University Of Northern Iowa Faculty Senate Meeting Agenda, April 11, 2011, University Of Northern Iowa. Faculty Senate.

Documents - Faculty Senate

Meeting agenda from the Faculty Senate of the University of Northern Iowa.

Fourth Annual Graduate Student Research Symposium [Program], 2011, University Of Northern Iowa

Annual Graduate Student Symposium Programs

Table of Contents
Welcome Letter from Dr. Michael Licari ••• 1
Listing of Judges, Notes ••• 2 / 3
Oral Presentations Listed by Room, in Order of Presentation ••• 4 / 8
Poster Presentations Listed by Program, Last Name ••• 9 / 14
Creative Performances Listed in Order of Performance ••• 14 / 16
Acknowledgements, Past Award Winners ••• 17 / 19 Alphabetical Listing of Participants ••• 20

Nfatc1 Affects Mouse Splenic B Cell Function By Controlling The Calcineurin–Nfat Signaling Network, Sankar Bhattacharyya, Jolly Deb, Amiya K. Patra, Pham Da Thuy, Wen Chen, Martin Vaeth, Friederike Berberich-Siebelt, Stefan Klein-Hessling, Edward D. Lamperti, Kurt Reifenberg, Julia Jellusova, Astrid Schweizer, Lars Nitschke, Ellen Leich, Andreas Rosenwald, Cornelia Brunner, Swen Engelmann, Ursula Bommhardt, Andris Avots, Martin R. Müller, Eisaku Kondo, Edgar Serfling

Peninsula Medical School

By studying mice in which the Nfatc1 gene was inactivated in bone marrow, spleen, or germinal center B cells, we show that NFATc1 supports the proliferation and suppresses the activation-induced cell death of splenic B cells upon B cell receptor (BCR) stimulation. BCR triggering leads to expression of NFATc1/αA, a short isoform of NFATc1, in splenic B cells. NFATc1 ablation impaired Ig class switch to IgG3 induced by T cell–independent type II antigens, as well as IgG3+ plasmablast formation. Mice bearing NFATc1−/− B cells harbor twofold more interleukin 10–producing B cells. NFATc1−/− B cells suppress the synthesis of interferon-γ by …

Medical School Watercooler Newsletter - April 10, 2011, Lindsey Lyle

Watercooler Newsletter

This is the April 10, 2011 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler

Contents Include

• April Med School Café - Potential Cures for Type I Diabetes

• USA Welcomes Pediatrics Practice Director

• Lectures Slated Honoring Legacy of Two of Mobile's Surgeons

• Preliminary Recommendations Released for New Version of MCAT

• USA College of Medicine Hosts 25th Anniversary BEAR Reunion

• Next Week's DSS - Dr. M. Celeste Simon

Jsim And Crm Synergistically Help Students To Model Breath-Dependent Drift When Deriving Tidal Volume From Pulmonary Airflow Measures, Nancy Pelaez, Trevor R. Anderson

PIBERG Presentations

No abstract provided.

Experimental Manipulation Of Maternal Investment And Effects On Juvenile Viability And Size In Physa Acuta, Lauren Awdziejcyk, William Jaeckle, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Effects Of Gender Based Descriptors On A Deity And A Corresponding Religious Group, Hannah Jones, Jennifer Daniels, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Uptake Of Dissolved Macromolecules By Larvae Of Lytechinus Variagatus, Andrew Mcdonald, William Jaeckle, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Comparison Of Eggshell Porosity And Estimated Gas Flux Between The Brown-Headed Cowbird (Molothrus Ater) And Its Hosts: The Dickcissel (Spiza Americana) And The Red-Winged Blackbird (Agelaius Phoeniceus), Brittany Childs, Miranda Kiefer, Given Harper, Faculty Advisor, William Jaeckle, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

An Enzyme Assay Of The Bchc-Encoded Enzyme 2-Desacetyl-2-Hydroxyethyl Bacteriochlorophyllide A Dehydrogenase, Ronald Grider, David Bollivar, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

The Evolution Of Social Pain: Understanding The Neural Network Of Social Ostracism Through Electroencephalogram Waves, Daniel Kern, Joseph Williams, Faculty Advisor

John Wesley Powell Student Research Conference

The lack of belonging or frequent exposure to social ostracism has maladaptive psychological and physical consequences. However, little is known about the mechanisms underlying the neural processes of social ostracism. Previously, Williams (2009) showed a decrease in theta power in the frontal lobe when female participants were ostracized in a virtual chat-room. Using male and female Illinois Wesleyan college students, this study manipulated two powerful social cues (biological sex and attractiveness level) to determine their effect on prefrontal brain activity in response to social ostracism in a virtual chat-room environment. Using EEG technology, frontal theta power (4-8Hz) was measured using …

Evaluation Of Dom Uptake By Spionid Polychaete Larvae From Antarctica, Travis Rosenkranz, William Jaeckle, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Evaluating The Effectiveness Of Conservation Education Incorporated In An Animal Exhibit At The Indianapolis Zoo, Vanessa Snyder, Given Harper, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Ph-Dependent 15-Lipoxygenase Catalyzed Peroxidation Of Linoleic Acid: Hplc/Esr/Ms Study, Shuting Zhong, Yan Gu, Preeti Purwaha, Benidict Law, Faculty Advisor, Steven Y. Qian, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Determining The Composition Of The Colony Tubes Of Pterobranchs, Andrew Mcdonald, Tyler Saunders, Elizabeth Balser, Faculty Advisor, Lukasz Sewera

John Wesley Powell Student Research Conference

No abstract provided.

A New Species Of Pristimantis (Amphibia: Anura: Strabomantidae) From The Río Abiseo National Park, Peru, Cindy Gregory, Edgar Lehr, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Winter Abundance Of Red-Tailed Hawks (Buteo Jamaicensis) And American Kestrels (Falco Sparverius) In Human-Altered Landscapes In Northeastern And Central Illinois, Anna Groves, Vic Berardi, Faculty Advisor, Paul Sweet, Faculty Advisor, Angelo Capparella, Faculty Advisor, Gretchen Knapp, Faculty Advisor, Given Harper, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

The Light/Lymphotoxin Costimulatory Family And Lipid Metabolism, Lukasz Sewera, Catherine A. Reardon, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

A New Species Of The Pristimantis Orestes Group (Amphibia: Anura: Strabomantidae) From Northern Peru (Río Abiseo National Park), Alan Brus, Edgar Lehr, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Incidence Of Larval Cloning In The Sea Urchins Arbacia Punctulata And Lytechinus Variegatus, Lauren Knaack, William Jaeckle, Faculty Advisor

John Wesley Powell Student Research Conference

No abstract provided.

Monitoring The Electrochemical Activity Of Biological Samples Using Scanning Electrochemical Microscopy, Erica Woodall, Melinda Baur, Faculty Advisor

John Wesley Powell Student Research Conference

The goal of the project is to develop the Scanning Electrochemical Microscopy (SECM) as a tool to study the biological effects of oxidative damage on rat pheochromocytoma cells (PCI2 cells). SECM is a useful tool for the analysis of biological samples because the ultramicroelectrode tip of the probe can detect the presence of electrochemically active compounds such as neurotransmitters, particularly dopamine and norepinephrine, while simultaneously characterizing the topography of the cell. The topography of the cell was determined by maintaining a constant distance between the tip of the electrode and the surface of the cell. In the collector mode, the …

Prevalence Of Methicillin Resistant Staphylococcus Aureus On Computer Mice On The Campus Of Southern Adventist University, Aldo J. Espinoza

Capstone Research Projects

Microorganisms are present everywhere in the environment. Unbeknownst to most people Staphylococcus aureus is a primary pathogen responsible for many skin infections and is carried by 25% of humans in the anterior nares. Due to the infective nature of Staphylococcus aureus, it is important to determine its prevalence on fomites by testing commonly used surfaces. For these reasons a research experiment was designed to determine the prevalence of S. aureus and Methicillin Resistant S. aureus (MRSA) in computer labs on the campus of Southern Adventist University during the fall semester of 2010. The research experiment was conducted in computer labs …

Interview With Matt Droter, Matt Droter

Oral Histories

No abstract provided.

Proposed Diversion Of Brookhaven National Laboratory's Sewage Treatment Plant Effluent From The Peconic River To Nearby Groundwater Recharge Basins, Douglas E. Paquette, Robert Lee, Jason Remien, Timothy Green

Long Island Geologists' Abstracts

Titles and Abstracts for the Confernence on "Geology of Long Island and Metropolitan New York,Long Island Geologists is a program of the Department of Geosciences at Stony Brook University. Each year, the activities include one or two field trips and, on a Saturday in April, a conference on the "Geology of Long Island and Metropolitan New York." Teachers and professional geologists can receive in-service credit for participating in these events. The abstracts contained within this collection are digital representations or copies of papers presented over the years at various conferences. For additional information on a particular topic or paper, contact …

Interview With Kent Miller, Kent Miller

Oral Histories

No abstract provided.

Interview With David Yoel, David Yoel

Oral Histories

No abstract provided.