Digital Commons Network^™

Grand Valley Forum, Volume 036, Number 04, September 19, 2011, Grand Valley State University

2011-2012, Volume 36

Grand Valley Forum is Grand Valley State's faculty and staff newsletter, published from 1976 to the present.

Faculty Senate Executive Committee Agenda, September 19, 2011, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Educational Policies Committee Annual Report - Larry Smith
• Honors Program Report - Christie Fox
• Library Advisory Council Report - Joe Tainter
• Parking Committee Report - James Nye
• Ad Hoc Committee on Post-Tenure Review - Glenn McEvoy
• EPC Items
• PRPC Vacancies and New VP
• Communication between Faculty Senate and the Faculty

Reciprocal Effects Of Oxidative Stress On Heme Oxygenase Expression And Activity Contributes To Reno-Vascular Abnormalities In Ec-Sod Knockout Mice, Tomoko Kawakami, Nitin Puri, Komal Sodhi, Lars Bellner, Toru Takahashi, Kiyoshi Morita, Rita Rezzani, Tim D. Oury, Nader G. Abraham

Biochemistry and Microbiology

Heme oxygenase (HO) system is one of the key regulators of cellular redox homeostasis which responds to oxidative stress (ROS) via HO-1 induction. However, recent reports have suggested an inhibitory effect of ROS on HO activity. In light of these conflicting reports, this study was designed to evaluate effects of chronic oxidative stress on HO system and its role in contributing towards patho-physiological abnormalities observed in extracellular superoxide dismutase (EC-SOD, SOD3) KO animals. Experiments were performed in WT and EC-SOD^(−/−) mice treated with and without HO inducer, cobalt protoporphyrin (CoPP). EC-SOD^(−/−) mice exhibited oxidative stress, renal histopathological abnormalities, …

Daily Eastern News: September 19, 2011, Eastern Illinois University

September

No abstract provided.

River Stewards Featured In University Of Dayton Magazine, University Of Dayton

Blog Archive: River Reflections at the University of Dayton

Last summer the River Stewards spent time with the staff of the University of Dayton Magazine, while they collected information and gained first hand experiences for the article in this Fall's edition. Click here to view article.

Berecek Appointed Professor Emerita Of Physiology And Biophysics, Alicia Rohan

Browse All News

No abstract provided.

New Facility Spurs Biomedical Research, Faculty Recruitment, Tyler Greer

Browse All News

No abstract provided.

Aebp2 As An Epigenetic Regulator For Neural Crest Cells, Hana Kim, Keunsoo Kang, Muhammad B. Ekram, Tae Young Roh, Joomyeong Kim

Faculty Publications

Aebp2 is a potential targeting protein for the mammalian Polycomb Repression Complex 2 (PRC2). We generated a mutant mouse line disrupting the transcription of Aebp2 to investigate its in vivo roles. Aebp2-mutant homozygotes were embryonic lethal while heterozygotes survived to adulthood with fertility. In developing mouse embryos, Aebp2 is expressed mainly within cells of neural crest origin. In addition, many heterozygotes display a set of phenotypes, enlarged colon and hypopigmentation, similar to those observed in human patients with Hirschsprung's disease and Waardenburg syndrome. These phenotypes are usually caused by the absence of the neural crest-derived ganglia in hindguts and melanocytes. …

The Collegian (2011-09-19), Rene Cardona Jr.

UTB/TSC Archives - The Collegian [Newspaper]

Vol. 64. No. 5

Asymmetrical Gene Flow In A Hybrid Zone Of Hawaiian Schiedea (Caryophyllaceae) Species With Contrasting Mating Systems., Lisa E. Wallace, Theresa M. Culley, Stephen G. Weller, Ann K. Sakai, Ashley Kuenzi, Tilottama Roy, Warren L. Wagner, Molly Nepokroeff

CAS Publications

Asymmetrical gene flow, which has frequently been documented in naturally occurring hybrid zones, can result from various genetic and demographic factors. Understanding these factors is important for determining the ecological conditions that permitted hybridization and the evolutionary potential inherent in hybrids. Here, we characterized morphological, nuclear, and chloroplast variation in a putative hybrid zone between Schiedea menziesii and S. salicaria, endemic Hawaiian species with contrasting breeding systems. Schiedea menziesii is hermaphroditic with moderate selfing; S. salicaria is gynodioecious and wind-pollinated, with partially selfing hermaphrodites and largely outcrossed females. We tested three hypotheses: 1) putative hybrids were derived from natural crosses …

September 19, 2011 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Quantification Of Protein Group Coherence And Pathway Assignment Using Functional Association., Meghana Chitale, Shriphani Palakodety, Daisuke Kihara

Department of Biological Sciences Faculty Publications

Background

Genomics and proteomics experiments produce a large amount of data that are awaiting functional elucidation. An important step in analyzing such data is to identify functional units, which consist of proteins that play coherent roles to carry out the function. Importantly, functional coherence is not identical with functional similarity. For example, proteins in the same pathway may not share the same Gene Ontology (GO) terms, but they work in a coordinated fashion so that the aimed function can be performed. Thus, simply applying existing functional similarity measures might not be the best solution to identify functional units in omics …

The Daily Gamecock, Monday, September 19, 2011, University Of South Carolina, Office Of Student Media

September

No abstract provided.

The Regulation Of Skeletal Muscle Protein Turnover During The Progression Of Cancer Cachexia In The ApcMin/+ Mouse, James P. White, John W. Baynes, Stephen L. Welle, Matthew C. Kostek, Lydia E. Matesic, Shuichi Sato, James A. Carson

Faculty Publications

Muscle wasting that occurs with cancer cachexia is caused by an imbalance in the rates of muscle protein synthesis and degradation. The Apc(Min/+) mouse is a model of colorectal cancer that develops cachexia that is dependent on circulating IL-6. However, the IL-6 regulation of muscle protein turnover during the initiation and progression of cachexia in the Apc(Min/+) mouse is not known. Cachexia progression was studied in Apc(Min/+) mice that were either weight stable (WS) or had initial (≤5%), intermediate (6-19%), or extreme (≥20%) body weight loss. The initiation of cachexia reduced %MPS 19% and a further ∼50% with additional weight …

Pre Incident Indicator Analysis (Piia) System, Frank Gilfeather

Electrical & Computer Engineering Technical Reports

No abstract provided.

Telangiectasia Macularis Eruptiva Perstans: More Than Skin Deep, Casey E. Watkins, Winston B. Bokor, Stuart Leicht, George Youngberg, Guha Krishnaswamy

ETSU Faculty Works

Systemic mastocytosis is a rare disease involving the infiltration and accumulation of active mast cells within any organ system. By far, the most common organ affected is the skin. Cutaneous manifestations of mastocytosis, including Urticaria Pigmentosa (UP), cutaneous mastocytoma or telangiectasia macularis eruptive perstans (TMEP), may indicate a more serious and potentially life-threatening underlying disease. The presence of either UP or TMEP in a patient with anaphylactic symptoms should suggest the likelihood of systemic mastocytosis, with the caveat that systemic complications are more likely to occur in patients with UP. TMEP can usually be identified by the typical morphology, but …

Real-Time Contrast Enhancement To Improve Speech Recognition., Joshua M. Alexander, Rick L. Jenison, Keith R. Kluender

Department of Speech, Language, and Hearing Sciences Faculty Publications

An algorithm that operates in real-time to enhance the salient features of speech is described and its efficacy is evaluated. The Contrast Enhancement (CE) algorithm implements dynamic compressive gain and lateral inhibitory sidebands across channels in a modified winner-take-all circuit, which together produce a form of suppression that sharpens the dynamic spectrum. Normal-hearing listeners identified spectrally smeared consonants (VCVs) and vowels (hVds) in quiet and in noise. Consonant and vowel identification, especially in noise, were improved by the processing. The amount of improvement did not depend on the degree of spectral smearing or talker characteristics. For consonants, when results were …

Stimulant Reduction Intervention Using Dosed Exercise (Stride) - Ctn 0037: Study Protocol For A Randomized Controlled Trial, Madhukar H. Trivedi, Tracy L. Greer, Bruce D. Grannemann, Timothy S. Church, Eugene Somoza, Steven N. Blair, Jose Szapocznik, Mark Stoutenberg, Chad Rethorst, Diane Warden, Kolette M. Ring, Robrina Walker, David W. Morris, Andrzej S. Kosinski, Tiffany Kyle, Bess H. Marcus, Becca Crowell, Neal Oden, Edward Nunes

Faculty Publications

Background: There is a need for novel approaches to the treatment of stimulant abuse and dependence. Clinical data examining the use of exercise as a treatment for the abuse of nicotine, alcohol, and other substances suggest that exercise may be a beneficial treatment for stimulant abuse, with direct effects on decreased use and craving. In addition, exercise has the potential to improve other health domains that may be adversely affected by stimulant use or its treatment, such as sleep disturbance, cognitive function, mood, weight gain, quality of life, and anhedonia, since it has been shown to improve many of these …

Rhythmic Leptin Is Required For Weight Gain From Circadian Desynchronized Feeding In The Mouse, Deanna M. Arble, Martha H. Vitaterna, Fred W. Turek

Biological Sciences Faculty Research and Publications

The neuroendocrine and metabolic effects of leptin have been extensively researched since the discovery, and the later identification, of the leptin gene mutated within the ob/ob mouse. Leptin is required for optimal health in a number of physiological systems (e.g. fertility, bone density, body weight regulation). Despite the extensive leptin literature and many observations of leptin’s cyclical pattern over the 24-hour day, few studies have specifically examined how the circadian rhythm of leptin may be essential to leptin signaling and health. Here we present data indicating that a rhythmic leptin profile (e.g. 1 peak every 24 hours) leads to excessive …

Volume 11, Issue 32: September 19, 2011, Women's Studies & Gender Studies Program

Women's Studies & Gender Studies: Digest Magazine

No abstract provided.

2d Dige Analysis Of Maternal Plasma For Potential Biomarkers Of Down Syndrome., Wendy E. Heywood, Tracey E. Madgett, Darrell Wang, Amanda Wallington, Julie Hogg, Kevin Mills, Neil D. Avent

School of Biomedical Sciences

BACKGROUND: Prenatal screening for Down Syndrome (DS) would benefit from an increased number of biomarkers to improve sensitivity and specificity. Improving sensitivity and specificity would decrease the need for potentially risky invasive diagnostic procedures. RESULTS: We have performed an in depth two-dimensional difference gel electrophoresis (2D DIGE) study to identify potential biomarkers. We have used maternal plasma samples obtained from first and second trimesters from mothers carrying DS affected fetuses compared with mothers carrying normal fetuses. Plasma samples were albumin/IgG depleted and expanded pH ranges of pH 4.5 - 5.5, pH 5.3 - 6.5 and pH 6 - 9 were …

Relationships Between Self-Reported Smoking, Household Environmental Tobacco Smoke Exposure And Depressive Symptoms In A Pregnant Minority Population, Sylvia Tan, Lauren P. Courtney, Ayman El-Mohandes, Susan M. Blake, Marie G. Gantz, Jutta Thornberry, M. Nabil El-Khorazaty, David Perry, Michele Kiely

Publications and Research

This study sought to examine relationships between depressive symptoms and prenatal smoking and/or household environmental tobacco smoke exposure (HHETSE) among urban minority women. We analyzed private, audio computer-assisted self interview data from a clinic-based sample of 929 minority pregnant women in Washington, DC. Depressive symptoms were assessed via the Beck Depression Inventory Fast Screen. HH-ETSE, current smoking, and former smoking were assessed via self-report. Depression levels and demographic characteristics were compared: (1) among nonsmokers, for those reporting HH-ETSE versus no HH-ETSE; and (2) among smokers, for those reporting current smoking (in last 7 days) versus former smokers. Measures associated with …

Comparisons Of Measurements And Predictions Of Pm Concentrations And Emission Rates From A Wind Erosion Event, K. D. Moore, M. D. Wojcik, C. C. Marchant, R. S. Martin, R. L. Pfeiffer, J. H. Prueger, J. L. Hatfield

Space Dynamics Laboratory Publications

Wind erosion can affect agricultural productivity, soil stability, and air quality. Air quality concerns deal mainly with human health and welfare issues, but are also related to long range transport and deposition of crustal materials. Regulatory standards for ambient levels of particulate matter (PM) with equivalent aerodynamic diameters ≤ 10 μm (PM10) and ≤ 2.5 μm (PM2.5) have been established in many countries in an effort to protect the health and welfare of their citizens. Wind erosion events may lead to high PM levels that exceed air quality standards and are health hazards. Quantifying suspended wind-blown dust emissions and resulting …

Chancellor's Report 2011-09, John Pugh

Chancellor's Report

No abstract provided.

Identification And Comparative Analysis Of Drought-Associated Micrornas In Two Cowpea Genotypes, Blanca E. Barrera-Figueroa, Lei Gao, Ndeye N. Diop, Zhigang Wu, Jeffrey D. Ehlers, Philip A. Roberts, Timothy J. Close, Jian-Kang Zhu, Renyi Liu

Department of Horticulture & Landscape Architecture Faculty Publications

Background

Cowpea (Vigna unguiculata) is an important crop in arid and semi-arid regions and is a good model for studying drought tolerance. MicroRNAs (miRNAs) are known to play critical roles in plant stress responses, but drought-associated miRNAs have not been identified in cowpea. In addition, it is not understood how miRNAs might contribute to different capacities of drought tolerance in different cowpea genotypes.

Results

We generated deep sequencing small RNA reads from two cowpea genotypes (CB46, drought-sensitive, and IT93K503-1, drought-tolerant) that grew under well-watered and drought stress conditions. We mapped small RNA reads to cowpea genomic sequences and …

Melt Regimes, Stratigraphy, Flow Dynamics And Glaciochemistry Of Three Glaciers In The Alaska Range, Seth Campbell, Karl Kreutz, Erich Osterberg, Steven Arcone

Dartmouth Scholarship

We used ground-penetrating radar (GPR), GPS and glaciochemistry to evaluate melt regimes and ice depths, important variables for mass-balance and ice-volume studies, of Upper Yentna Glacier, Upper Kahiltna Glacier and the Mount Hunter ice divide, Alaska. We show the wet, percolation and dry snow zones located below 2700ma.s.l., at 2700 to 3900ma.s.l. and above 3900ma.s.l., respectively. We successfully imaged glacier ice depths upwards of 480m using 40–100MHz GPR frequencies. This depth is nearly double previous depth measurements reached using mid-frequency GPR systems on temperate glaciers. Few Holocene-length climate records are available in Alaska, hence we also assess stratigraphy and flow …

Commentary

Jefferson Journal of Psychiatry

DR. KRAMER COMMENTS ON PSYCHOACTIVITY OF CALCIUM CHANNEL BLOCKERS, CASE REPORTS, AND RESEARCH.

Masson's Assault On Truth: A Critique, Emmanuel E. Garcia, Md

Jefferson Journal of Psychiatry

In his book, The Assault on Truth, j. M. Masson (I) proposes to challenge the very foundations of psychoanalysis by showing how Freud 's abandonment of the so-called seduction theory of the etiology of neurosis was erroneously predicated.

Masson's argument, in essence, may be summarized as follows. Freud, while studying with the eminent neurologist Charcot in Paris (from October 1885 to February 1886), found himself exposed to the prevalent horrors of ch ild abuse, which were copiously detailed in the French medical literature at the time, and which were very probably demonstrated to him at the …

Should Psychotherapy Be Taught To Psychiatric Residents? A Debate., Donald W. Black, Md, John Ascher, Md, Hal Cash, Md, John Markowitz, Md, Paul Hamburg, Md, Jeffrey Satinover, Md, Alan Mellow, Md

Jefferson Journal of Psychiatry

Much of this discussion was inspired by a debate held at the 1984 APA Annual Meeting, entitled " Does Psychodynamic Theory Have Little Relevance to Contemporary Psychiatric Care?" We saw the need for a debate, resident generated, that would address a corollary issue in residency training.

Our program will include an introduction, a debate involving statements for the affirmative, that is, that psychotherapy should be taught to psychiatric residents, and two statements for the negative, that psychotherapy should not be taught to psychiatric residents. Concluding remarks will follow.

If our title is provocative , if what we have to say …

A Review Of Ethnopsychiatric Studies Of Depression, Nancy E. Wilson, Ab, Daniel R. Wilson, Md

Jefferson Journal of Psychiatry

One of the common goals in medical anthropology is to elucidate the significance of culture in determining health and thus clarify the complex biopsychosocial model to provide better, more appropriate care (I). Prominent among environmental influences is the society in which a person develops: and it is his position in this constellation of people, with their shared ethos and world view, which molds experience, cognition, and affect (2). Cultural meanings, norms, and power arrangements shape illness to a great degree by defining the sick role and consequent illness behaviors. Medical anthropology, as a discipline, has among its concerns the cultural …