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Low Serum Concentration Facilitates The Differentiation Of Hepatic Progenitor Cells, Yun He, Wei-Yu Zhang, Min Gong, Jia-Yi Huang, Ni Tang, Tao Feng, Guang-Hui Wei, Tong-Chuan He, Yang Bi

Saudi Medical Journal

OBJECTIVE: To investigate the effect of serum culture conditions on the differentiation of hepatic progenitor cells (HPCs) in vitro. METHODS: This study was conducted at the Stem Cell Biology and Therapy Laboratory, The Children9s Hospital of Chongqing Medical University, Chongqing, China from August 2009 to June 2010. Differentiation of HPCs was induced with dexamethasone, hepatic growth factor, and fibroblast growth factor-4 in 10% fetal bovine serum (FBS), 2% FBS, 2% horse serum (HS) conditions. First, we investigated the indirect synthesis of albumin by the albumin promoter-driven Gaussia luciferase assay, and cell proliferation by cell counting. Then, we performed reverse transcriptase-polymerase …

Meningitis And Seasonal Influenza Vaccination Coverage Among Military Personnel In Central Saudi Arabia, Hesham I. Al-Khashan, Mohei A. Selim, Adel M. Mishriky, Abdulaziz A. Binsaeed

Saudi Medical Journal

OBJECTIVE: To determine the meningitis and influenza vaccination coverage rates among Saudi military personnel in Riyadh (Central Military Region [CMR]), Kingdom of Saudi Arabia, (KSA) and the socio-demographic factors that influence vaccination. METHODS: This cross-sectional descriptive study was carried out on a sample of 2286 military personnel from different army forces and different military ranks in CMR in KSA selected by a 2-stage stratified random sampling technique. A self-administered questionnaire designed for the National Military Health Survey was used with a section added for assessment of vaccination status. Data collection was carried out from May to August 2009. RESULTS: The …

Bacterial Killing By Dry Metallic Copper Surfaces, Christophe Espírito Santo, Ee Wen Lam, Christian Elowsky, Davide Quaranta, Dylan W. Domaille, Christopher J. Chang, Gregor Grass

Nebraska Center for Biotechnology: Faculty and Staff Publications

Metallic copper surfaces rapidly and efficiently kill bacteria. Cells exposed to copper surfaces accumulated large amounts of copper ions, and this copper uptake was faster from dry copper than from moist copper. Cells suffered extensive membrane damage within minutes of exposure to dry copper. Further, cells removed from copper showed loss of cell integrity. Acute contact with metallic copper surfaces did not result in increased mutation rates or DNA lesions. These findings are important first steps for revealing the molecular sensitive targets in cells lethally challenged by exposure to copper surfaces and provide a scientific explanation for the use of …

Phylogenetic Diversity And Genotypical Complexity Of H9n2 Influenza A Viruses Revealed By Genomic Sequence Analysis, Guoying Dong, Jing Luo, Hong Zhang, Chengmin Wang, Mingxing Duan, Thomas Jude Deliberto, Dale L. Nolte, Guangju Ji, Hongxuan He

United States Department of Agriculture Wildlife Services: Staff Publications

H9N2 influenza A viruses have become established worldwide in terrestrial poultry and wild birds, and are occasionally transmitted to mammals including humans and pigs. To comprehensively elucidate the genetic and evolutionary characteristics of H9N2 influenza viruses, we performed a large-scale sequence analysis of 571 viral genomes from the NCBI Influenza Virus Resource Database, representing the spectrum of H9N2 influenza viruses isolated from 1966 to 2009. Our study provides a panoramic framework for better understanding the genesis and evolution of H9N2 influenza viruses, and for describing the history of H9N2 viruses circulating in diverse hosts. Panorama phylogenetic analysis of the eight …

Education And Levels Of Salivary Cortisol Over The Day In Us Adults, Jennifer B. Dowd, Nalini Ranjit, D. Phuong Do, Elizabeth A. Young, James S. House, George A. Kaplan

Faculty Publications

Background - Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis is hypothesized to be an important pathway linking socioeconomic position and chronic disease.

Purpose - This paper tests the association between education and the diurnal rhythm of salivary control.

Methods - Up to 8 measures of cortisol (mean of 5.38 per respondent) over two days were obtained from 311 respondents aged 18-70, drawn from 2001-2002 Chicago Community Adult Health Study. Multi-level models with linear splines were used to estimate waking level, rates of cortisol decline, and area-under-the-curve over the day, by categories of education.

Results - Lower education (0-11 years) was associated …

Artificial Cognitive Memory - Changing From Density Driven To Functionality Driven, Luping Shi, Kaijun Yi, Kiruthika Ramanathan, Rong Zhao, Ning Ning, Ding Ding, Tow Chong Chong

Research Collection School Of Computing and Information Systems

Increasing density based on bit size reduction is currently a main driving force for the development of data storage technologies. However, it is expected that all of the current available storage technologies might approach their physical limits in around 15 to 20 years due to miniaturization. To further advance the storage technologies, it is required to explore a new development trend that is different from density driven. One possible direction is to derive insights from biological counterparts. Unlike physical memories that have a single function of data storage, human memory is versatile. It contributes to functions of data storage, information …

Coming To America: Multiple Origins Of New World Geckos, Tony Gamble, A. M. Bauer, G. R. Colli, E. Greenbaum, T. R. Jackman, Laurie J. Vitt, Andrew M. Simons

Biological Sciences Faculty Research and Publications

Geckos in the Western Hemisphere provide an excellent model to study faunal assembly at a continental scale. We generated a time-calibrated phylogeny, including exemplars of all New World gecko genera, to produce a biogeographic scenario for the New World geckos. Patterns of New World gecko origins are consistent with almost every biogeographic scenario utilized by a terrestrial vertebrate with different New World lineages showing evidence of vicariance, dispersal via temporary land bridge, overseas dispersal, or anthropogenic introductions. We also recovered a strong relationship between clade age and species diversity, with older New World lineages having more species than more recently …

Accelerated Stress Testing Of Hydrocarbon-Based Encapsulants For Medium-Concentration Cpv Applications, M. D. Kempe, T. J. Moricone, M. Kilkenny, J. Z. Zhang

Publications (E)

Concentrating photovoltaic (CPV) systems have great potential to reduce photovoltaic (PV) electricity costs because of the relatively low cost of optical components as compared to PV cells. A transparent polymeric material is used to optically couple the PV cell to optical components and is thus exposed to the concentrated light source at elevated temperatures. In this work polymeric encapsulant materials are positioned close to a Xenon arc lamp to expose them to ultraviolet radiation (UV) that is about 42 times as intense as sunlight. Furthermore, different glass types are used as filters to modify the spectral distribution of light in …

The Ohio Bioscience Industry, 2000-2009, Ziona Austrian, Candice Clouse, Matthew Hrubey

All Maxine Goodman Levin School of Urban Affairs Publications

No abstract provided.

Markov Models For Biogeography-Based Optimization, Daniel J. Simon, Mehmet Ergezer, Dawei Du, Rick Rarick

Electrical and Computer Engineering Faculty Publications

Biogeography-based optimization (BBO) is a population-based evolutionary algorithm that is based on the mathematics of biogeography. Biogeography is the science and study of the geographical distribution of biological organisms. In BBO, problem solutions are analogous to islands, and the sharing of features between solutions is analogous to the migration of species. This paper derives Markov models for BBO with selection, migration, and mutation operators. Our models give the theoretically exact limiting probabilities for each possible population distribution for a given problem. We provide simulation results to confirm the Markov models.

The Same Face Of The Two Smiths: Adam Smith And Vernon Smith, Maria Pia Paganelli

Economics Faculty Research

Going from personal to impersonal exchange seems to be a relevant feature that allows humans to develop complex societies and grow prosperous. Adam Smith's idea of moral imagination, embodied in the impartial spectator and achieved through sympathy, may integrate and complement today's evolutionary biology and experimental economic explanations, providing the missing key as to how we generate and internalize those rules of conduct that promote fair and cooperative behaviors.

South Dakota Wheat Fungicide Recommendations, Lawrence Osborne, Jeff Stein

SDSU Extension Fact Sheets

No abstract provided.

Follicle-Stimulating Hormone Promotes Rank Expression On Human Monocytes, Joseph G. Cannon, Barbara Kraj, Gloria Sloan

School of Medical Diagnostics & Translational Sciences Publications

Elevated serum concentrations of follicle-stimulating hormone (FSH) are associated with diminished bone density in women, beginning years before menopause and the decline in estradiol. We hypothesized that FSH promotes development of myeloid cells toward the bone-resorbing osteoclast phenotype. This was tested by isolating peripheral blood mononuclear cells from nine healthy adults, incubating them in the presence of FSH at three different concentrations spanning the physiological range, and then measuring the expression of receptor activator for NF-κB (RANK, a surface marker for osteoclasts) on CD14+ cells by flow cytometry. In the absence of FSH, 3.3±0.5% of the cells expressed high levels …

Utilization Of Geographic Information System For Research, Management, And Education In The Natural Resources Management Department At California Polytechnic State University, San Luis Obispo, David In Yun

Master's Theses

Geographic Information System (GIS) is “an organized collection of computer hardware, software, geographic data, and personnel designed to efficiently capture, store, update, manipulate, analyze, and display all forms of geographically referenced information” (ESRI, 1997a). The Natural Resources Management Department at California Polytechnic State University, San Luis Obispo, California, hereafter NRM, was one of the early users of GIS technology. Although GIS was primarily used as an educational tool, it was also used for cataloging and displaying resource information for management planning and research projects. As the computing technology advanced, GIS became more powerful and easier to use. NRM faculty and …

Laser Etched Pmma Microfluidic Chip Design And Manufacture With Applications In Capillary Zone Electrophoresis, Evan Allen Barbre

Master's Theses

This thesis encompasses a feasibility study of using low-cost materials to manufacture microfluidic chips that can perform the same functions as chips manufactured using traditional methods within an acceptable range of efficiency of chips created with more exotic methods and materials. The major parts of the project are the selection and characterization of the fabrication methods for creating the channels for fluid flow, the methods for sealing the channels to create a usable chip and the electrophoretic separations of carboxylated microspheres of different potentials. In this work we seek to answer the question if laser-etched PMMA microfluidic chips are comparable …

A Microsimulation Of Traffic, Parking, And Emissions At California Polytechnic State University – San Luis Obispo, Steven Michael Kilbert

Master's Theses

Traffic and parking congestion are significant issues at many universities nationwide. The delays experienced result in wasted time, money, and fuel for students, faculty and staff, not to mention the negative contributions to the environment. This paper quantifies the amount of vehicle emissions generated during an average morning peak hour in the university environment. Using VISSIM and CMEM microsimulation packages, a model is created for California Polytechnic State University- San Luis Obispo to aggregate the collective transportation behaviors and practices of the campus and recognize the implications these behaviors pose on the transportation network as a whole. Reasonable estimates are …

Sar Map Of Gel Phantom In A 64mhz Mri Birdcage By Fiber-Optic Thermometry And Fdtd Simulation, Chirag Mukesh Patel

Master's Theses

As implantable medical devices are being used more often to treat medical problems for which pharmaceuticals don’t suffice, it is important to understand their interactions with commonly used medical modalities. The interactions between medical implants and Magnetic Resonance Imaging machines have proven to be a risk for patients with implants.

Implanted medical devices with elongated metallic components can create harmful levels of local heating in a Magnetic Resonance Imaging (MRI) environment [1]. The heating of a biological medium under MRI is monitored via the Specific Absorption Rate (SAR). SAR, defined as power absorbed per unit mass (W/kg), can be calculated …

Race- And Sex-Related Differences In Retinal Thickness And Foveal Pit Morphology, Melissa Wagner-Schuman, Adam M. Dubis, Rick Nordgren, Yuming Lei, Daniel Odell, Hellen Chiao, Eric Weh, William Fischer, Yusufu N. Sulai, Alfredo Dubra, Joseph Carroll

Biomedical Engineering Faculty Research and Publications

Purpose.

To examine sex- and race-associated differences in macular thickness and foveal pit morphology by using spectral-domain optical coherence tomography (SD-OCT).

Methods.

One hundred eighty eyes of 90 healthy patients (43 women, 47 men) underwent retinal imaging with spectral-domain OCT. The lateral scale of each macular volume scan was corrected for individual differences in axial length by ocular biometry. From these corrected volumes, Early Treatment Diabetic Retinopathy Study (ETDRS) grids of retinal thickness were generated and compared between the groups. Foveal morphology was measured with previously described algorithms.

Results.

Compared with the Caucasians, the Africans and African Americans had reduced …

The Predictive Mirror: Interactions Of Mirror And Affordance Processes During Action Observation, P Bach, Ap Bayliss, Sp Tipper

School of Psychology

An important question for the study of social interactions is how the motor actions of others are represented. Research has demonstrated that simply watching someone perform an action activates a similar motor representation in oneself. Key issues include (1) the automaticity of such processes, and (2) the role object affordances play in establishing motor representations of others' actions. Participants were asked to move a lever to the left or right to respond to the grip width of a hand moving across a workspace. Stimulus-response compatibility effects were modulated by two task-irrelevant aspects of the visual stimulus: the observed reach direction …

Group Consensus, Individual Consent, Elizabeth Chamblee Burch

Scholarly Works

Despite a rise in the number of personal-injury and product-liability cases consolidated through multi-district litigation, a decline in class-certification motions, and several newsworthy nonclass settlements such as the $4.85 billion Vioxx settlement and estimated $700 million Zyprexa settlements, little ink has been spilled on nonclass aggregation’s unique issues. Sections 3.17 and 3.18 of the American Law Institute’s Principles of the Law of Aggregate Litigation are a noteworthy exception. This Article uses those principles as a lens for exploring thematic questions about the value of pluralism, group cohesion, governance, procedural justice, and legitimacy in nonclass aggregation.

Sections 3.17 and 3.18 make …

Religion And Attitudes Toward Same-Sex Marriage Among U.S. Latinos, Christopher G. Ellison, Gabriel A. Acevedo, Aida I. Ramos-Wada

Faculty Publications - Department of Sociology

Objectives. This study examines links between multiple aspects of religious involvement and attitudes toward same-sex marriage among U.S. Latinos. The primary focus is on variations by affiliation and participation, but the possible mediating roles of biblical beliefs, clergy cues, and the role of religion in shaping political views are also considered.

Methods. We use binary logistic regression models to analyze data from a large nationwide sample of U.S. Latinos conducted by the Pew Hispanic Forum in late 2006.

Results. Findings highlight the strong opposition to same-sex marriage among Latino evangelical (or conservative) Protestants and members of sectarian groups (e.g., LDS), …

Detection Of Ndm-1-Producing Klebsiella Pneumoniae In Kenya., Laurent Poirel, Gunturu Revathi, Sandrine Bernabeu, Patrice Nordmann

Pathology, East Africa

Seven carbapenem-resistant NDM-1-positive Klebsiella pneumoniae isolates were recovered from patients hospitalized between 2007 and 2009 in different wards at a referral and tertiary care center in Nairobi. Most of the isolates were obtained from urine. All isolates carried the bla_NDM-1 carbapenemase gene previously reported from India, Pakistan, and the United Kingdom. These isolates were clonally related and expressed many other resistance determinants, including β-lactamases CTX-M-15, OXA-1, OXA-9, CMY-6, and aminoglycoside resistance methylase RmtC. This work corresponds to the first report of NDM-1 producers in Africa.

Primary Amebic Meningoencephalitis Caused By Naegleria Fowleri, Karachi, Pakistan., Sadia Shakoor, Mohammad Asim Beg,, Syed Faisal Mahmood, Rebecca Bandea, Rama Sriram, Fatima Noman, Farheen Ali,, Govinda S. Visvesvara, Afia Zafar

Department of Medicine

We report 13 cases of Naegleria fowleri primary amebic meningoencephalitis in persons in Karachi, Pakistan, who had no history of aquatic activities. Infection likely occurred through ablution with tap water. An increase in primary amebic meningoencephalitis cases may be attributed to rising temperatures, reduced levels of chlorine in potable water, or deteriorating water distribution systems.

Plasticity In Patterns Of Histone Modifications And Chromosomal Proteins In Drosophila Heterochromatin, Nicole Riddle, Aki Minoda, Peter Kharchenko, Artyom Alekseyenko, Yuri Schwartz, Michael Tolstorukov, Andrey Gorchakov, Jacob Jaffe, Cameron Kennedy, Daniela Linder-Basso, Sally Peach, Gregory Shanower, Haiyan Zheng, Mitzi Kuroda, Vincenzo Pirrotta, Peter Park, Sarah C.R. Elgin, Gary Karpen

Biology Faculty Research

Eukaryotic genomes are packaged in two basic forms, euchromatin and heterochromatin. We have examined the composition and organization of Drosophila melanogaster heterochromatin in different cell types using ChIP-array analysis of histone modifications and chromosomal proteins. As anticipated, the pericentric heterochromatin and chromosome 4 are on average enriched for the "silencing" marks H3K9me2, H3K9me3, HP1a, and SU(VAR)3-9, and are generally depleted for marks associated with active transcription. The locations of the euchromatin-heterochromatin borders identified by these marks are similar in animal tissues and most cell lines, although the amount of heterochromatin is variable in some cell lines. Combinatorial analysis of chromatin …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Georgia Southern University to Host Organ Donation Awareness Event

Report: The Illinois State University Faculty-Staff Newsletter, February 1, 2011, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

Blood Pressure And Cerebral White Matter Share Common Genetic Factors In Mexican Americans, Peter Kochunov, David C. Glahn, Jack Lancaster, Anderson M. Winkler, Rene L. Olvera, Joanne E. Curran, Thomas D. Dyer, Laura Almasy, Ravi Duggirala, Peter T. Fox, John Blangero

School of Medicine Publications

Elevated arterial pulse pressure and blood pressure (BP) can lead to atrophy of cerebral white matter (WM), potentially attributable to shared genetic factors. We calculated the magnitude of shared genetic variance between BP and fractional anisotropy of water diffusion, a sensitive measurement of WM integrity in a well-characterized population of Mexican Americans. The patterns of whole-brain and regional genetic overlap between BP and fractional anisotropy were interpreted in the context the pulse-wave encephalopathy theory. We also tested whether regional pattern in genetic pleiotropy is modulated by the phylogeny of WM development. BP and high-resolution (1.7 × 1.7 × 3 mm; …

Illinois State Alumni Magazine, February 2011, Illinois State University, University Marketing And Communications

State: The Magazine of Illinois State University (1999-present)

Illinois State University alumni magazine

Facing The Unfaceable: Dealing With Prosecutorial Denial In Postconviction Cases Of Actual Innocence, Aviva Orenstein

San Diego Law Review

This Article develops a question that intrigued Fred: prosecutors’ duties postconviction to prisoners who might be innocent. Although Fred wrote about a panoply of questions that arise regarding the prosecutor’s duty to “do justice” after conviction, this Article will address one specific area of concern: how and why prosecutors resist allowing DNA testing and, more startlingly, deny the obvious implications of DNA evidence when that evidence exonerates the convicted.

Part II of this Article briefly summarizes two of Fred’s major articles on the subject of prosecutorial ethics. Part III documents the problem of postconviction DNA exonerations and prosecutors’ varied reactions. …

Climate-Related Challenges In Long-Term Management Of Säkylän Pyhäjärvi (Sw Finland), Anne Mari Ventelä, Teija Kirkkala, Amaury Lendasse, Marjo Tarvainen, Harri Helminen, Jouko Sarvala

Engineering Management and Systems Engineering Faculty Research & Creative Works

Säkylän Pyhäjärvi (Sw Finland) is an Example of a Large and Shallow Lake Suffering from Eutrophication. during the Last 20 Years, the Quality and General Usability of Water in Pyhäjärvi Have Shown Considerable Variation Driven by Both a Variety of Human Activities and Climate-Related Factors Such as Wet and Dry Years. the Lake Has Been Thoroughly Studied for Decades and Has Been the Object of Comprehensive Restoration Activities Both in the Catchment and in the Lake Since the 1990s. Large Variety of Water Protection Measures Like Wetlands, Sedimentation Ponds and Filtering Systems Have Been Implemented in the Catchment Area to …