Entire DC Network | Open Access Articles | Digital Commons Network™

Choking Out Local Community Service Organizations: Rising Federal Tax Regulation And Its Impact On Small Nonprofit Entities, Nicole S. Dandridge

Kentucky Law Journal

No abstract provided.

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Spare The Rod, Spoil The Litigator? The Varying Degrees Of Culpability Required For An Adverse Inference Sanction Regarding Spoliation Of Electronic Discovery, Lauren R. Nichols

Kentucky Law Journal

No abstract provided.

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Material Witness Detentions After Al-Kidd, Wesley Macneil Oliver

Kentucky Law Journal

No abstract provided.

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Non-Prisoner Pro Se Litigation In The United States District Court For The Eastern District Of Kentucky: Analyzing 2004 And 2007 Cases From Filing To Termination, Timothy D. Thompson

Kentucky Law Journal

No abstract provided.

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The Effect Of Using E-Learning Tools In Online And Campus-Based Classrooms On Student Performance, Edith Galy, Clara Downey, Jennie Johnson

International Business and Entrepreneurship Faculty Publications

Creating an integrative research framework that extends a model frequently used in the Information Systems field, the Technology Acceptance Model, together with variables used in the Education field, this empirical study investigates the factors influencing student performance as reflected by their final course grade. The Technology Acceptance Model explains computer acceptance in general terms. The model measures the impact of external variables on internal beliefs, attitudes, and intentions. Perceived Usefulness and Perceived Ease of Use, two main constructs in the model, refer to an individual's perception of how the adoption of a new technology will increase their efficiency, and the …

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Credit-Monitoring Damages In Cybersecurity Tort Litigation, Vincent R. Johnson

Faculty Articles

When someone improperly accesses or discloses an individual’s personal information, the subject of that data breach is often at an increased risk of identity theft. One way for an affected data subject to guard against this risk is to subscribe to a credit-monitoring service. Recently, potential cybersecurity defendants have provided credit-monitoring services to affected data subjects voluntarily, and courts have approved credit-monitoring compensation as part of class-action settlements. These developments demonstrate that credit-monitoring expenditures are both reasonable and necessary when a serious breach of data security occurs. Furthermore, the economic loss rule should not bar recovery of credit-monitoring damages because …

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Federal Rules Pending Public Comment, David A. Schlueter

Faculty Articles

In August 2011, the Administrative Office of the United States Courts published several rules for public comment. The amendment to Rule 11 would require the judge to apprise a defendant who wishes to plead guilty that, if convicted and not a United States citizen, the defendant may be deported, denied citizenship, and denied future admission to the United States. Several amendments have been proposed for Rule 12 with reference to the appropriate times for pleadings and pretrial motions, and the consequences and standards of review for untimely motions. The change to Rule 34 is intended to conform the rule to …

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Conference Program [2011], Georgia International Conference On Information Literacy

Georgia International Conference on Information Literacy

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Daoist Elements In Cai Guo-Qiang's Inopportune And Head On, Kelley Wockenfuss

All ETDs from UAB

This thesis explores the Daoist elements in two of contemporary Chinese artist Cai Guo-Qiang's (1957 - ) largest installations to date, Inopportune (2004) and Head On (2006). Comprising multi-media works including gunpowder paintings, simulated animal forms, and firework displays, the two installations explore themes related to the global threat of terrorism in Inopportune and the history of the Berlin Wall in Head On. In exploring these themes, Cai attempts to create a globally accessible dialogue by emphasizing universal elements related to the forces of creation and destruction. For this reason he implements the Daoist characteristics of yin and yang in …

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Role Of Vdr In Host Immune Response To Porphyromonas Gingivalis Infection, Gulam Yezdani

All ETDs from UAB

Porphyromonas gingivalis is one of the etiologic factors of periodontal disease, a chronic inflammatory disorder characterized by the destruction of periodontal connective tissue and the subsequent loss of alveolar bone. Epidemiological and genetic studies have indicated an association between periodontal disease and the vitamin D system. However, little is known regarding how vitamin D signaling regulates the inflammatory immune process of this disease. The purpose of the study was to understand the role of the vitamin D receptor (VDR) in regulating the host response to P. gingivalis infection by using a dual chamber mouse model. These chambers served both as …

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Piggybac Transposon Mutagenesis In Human And Mouse Stem Cells, Tingting Zhang

All ETDs from UAB

The most common genetic diseases worldwide, £] thalassemia and Sickle Cell Anemia (SCA) result from mutations in the adult £] globin gene. One promising therapeutic method to ameliorate these diseases is to reactivate the endogenous fetal fÃ globin gene. I hypothesize that an erythroid mutagenic transposon system can be used to activate fÃ globin gene expression. To test this hypothesis three lines of genetically modified mice were generated and bred together. The first is a transgenic mouse line that contains a multicopy array of erythroid mutagenic PiggyBac (PB) transposons. The second transgenic mouse line expresses the PB transposase (TPase) from …

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Modeling Incident And Emergency Management From A Regional Perspective, Ozge Cavusoglu

All ETDs from UAB

Traffic incidents and natural or man-made disasters can impose significant safety risks and disruptions on traffic flows, often resulting in non-recurring congestion. Congestion, in turn, may impede the ability of EMS (Emergency Medical Services) to provide timely response to those in need of medical attention. Thus, it is important to understand the potential impacts of incidents and emergencies on traffic network operations and develop response strategies with a potential of minimizing such impacts on traffic operations, emergency response and the safety of the traveling public. The objective of the dissertation was twofold: a. Study incident management options and benefits from …

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Limited Transplantation Of Antigen-Expressing Hematopoietic Stem Cells Induces Long-Lasting Cytotoxic T Cell Responses And Effect Of Altered Suppressive Myeloid Population On Hiv-Disease Progression, Warren L. Denning

All ETDs from UAB

While each type of cancer and chronic viral infection has its own specific pathology, they share two common mechanisms of immune evasion. The first mechanism is the exhaustion or deletion of antigen-specific T cells. The second mechanism is the formation of an immunosuppressive environment responsible for the block of T cell function. Elicitation of antigen-specific T cells be accomplished by immunotherapy in place of conventional treatments such as HAART and chemotherapy. In addition, immunotherapy can alleviate the side-effects associated with long-term use of conventional therapies while reducing the total cost. The results presented here provide an alternative to conventional methods …

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Role Of The Cardiomyocyte Circadian Clock In Modulating Myocardial Physiology And Pathophysiology, David Joseph Durgan

All ETDs from UAB

It is well established that multiple parameters of cardiovascular physiology and pathophysiology exhibit diurnal variations. For example, human heart rate and blood pressure peak during the morning and trough in the evening. Similarly, there is a morning prevalence for the onset of multiple adverse cardiovascular events, including myocardial ischemia, arrhythmias, and sudden cardiac death. Traditionally these rhythms have been attributed to rhythms in neurohumoral stimulation. However recent identification of the circadian clock mechanism in cardiovascular relevant cell types, including the cardiomyocyte, has prompted investigation into its role in modulating myocardial physiology and pathophysiology over the course of the day. Preliminary …

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Effects Of Growth Factor Induced Pathways On Differentiation Of The Human Neuronal Cell Line Sh-Sy-5y., Ashish D. Dwary

All ETDs from UAB

Background: The VSNL1 gene product, Visinin-like-protein-1 (VILIP-1), is a member of the neuronal EF-hand Ca2+-sensor protein family. Previously, VILIP-1 mRNA and protein expression were shown to be altered in animal models and in schizophrenia patients. VILIP-1 influences cytosolic cAMP levels, cell migration, exocytotic processes and differentiation in the periphery. This raises the question, whether similar to other potential schizophrenia susceptibility genes, such as Disc1, PDE4B and Akt, VILIP-1 may be associated with schizophrenia-related measures, and if it could mechanistically affect cAMP signaling and neurite outgrowth in neurons. Methods: 627 people with schizophrenia and 541 control subjects were ascertained and the …

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From Brown To Bakke: Race Change And The Birmingham City Schools, 1963-1983, Johnmark Allen Edwards

All ETDs from UAB

When in 1954 the US Supreme Court declared that "separate but equal" was inherently not equal, every segregated school system in America was supposed to desegregate. This was easier said than done, and more successful in some systems than others. Here is a case study of that episode in American history focused on Birmingham, Alabama. This city's tumultuous road to educational desegregation unfolded in four phases: non-compliance (1954-1963), incremental desegregation (1963-1967), "freedom of choice" (1967-1970) and zoned integration (1970-1983). In this context, the thesis has three objectives: first, to explore how people of Birmingham - black and white, male and …

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Ultrasound Elasticity Measurements As A Predictor For Arteriovenous Fistula Maturation, Anna Sorace

All ETDs from UAB

This research thesis examines the applicability of using ultrasound imaging to quantify arterial elasticity and assess potential of arteriovenous fistula maturation in chronic kidney disease (CKD) patients. Tissue-specific abnormalities have proven useful for identifying disease states within oncology, cardiovascular and musculoskeletal system. Using ultrasound-based imaging to evaluate arterial elasticity is a noninvasive and novel technique. It has the potential to contribute further insight into chronic kidney disease fistula failure and become a noninvasive prognostic indicator. Reliable vascular access is critical for delivery of adequate hemodialysis treatment to CKD patients and to maintain long-term connections for dialysis. An arteriovenous fistula is …

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The Effect Of Changes In Tort Laws On Cesarean Section Rates In The United States, Allison Jean Taylor

All ETDs from UAB

"Defensive medicine", medical practice decisions based on fear of malpractice litigation and where risks may outweigh health and cost benefits, is a proposed contributor to increasing cesarean rates in the U.S. Some studies suggest that changes in laws governing medical malpractice actions may decrease the cesarean rate by relieving pressures driving defensive medicine. This study examined whether, in states that have adopted certain tort reform measures, the probability of having a cesarean delivery is lower following implementation of the reform measures. A database of state legislation and court decisions and National Center for Health Statistics natality data files (1991-2004) were …

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Osteogenic Differentiation Of Human Mesenchymal Stem Cells Enhanced By Bone Ecm Analogous Nanomatrix Composites, Jeremy Benton Vines

All ETDs from UAB

A growing trend in the area of bone tissue engineering is the development of materials that mimic the native bone extracellular matrix (ECM). This need is typically met through the creation of composites, which attempt to recapitulate both the organic and inorganic components of the native bone ECM. However, few composites have been created with organic ECM analogous components that are functionalized to direct cellular behaviors. Furthermore, a majority of these studies do not investigate how the ratio of the inorganic and organic components affects cellular behaviors. To address this issue, hydroxyapatite nanoparticles (HANPs) were dispersed within peptide amphiphile (PA) …

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Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton

All ETDs from UAB

Nuclear receptor NR4A3 (NOR-1, MINOR) mediates transcriptional responses to ß-adrenergic signaling, is increased in insulin sensitive mice and humans, and enhances insulin-stimulated glucose transport in cultured adipocytes and myocytes. We therefore sought to determine the role of NR4A3 in in vivo adipose tissue and skeletal muscle physiology. Following adipose-specific NR4A3 over-expression in mice, we observed reduced circulating epinephrine due to enhanced catabolism of catecholamines in adipose tissue. Furthermore, this reduction in circulating epinephrine produced broad physiological consequences, including poor glucose tolerance, reduced insulin sensitivity, dyslipidemia, poor cardiac function, and behavioral alterations. In skeletal muscle, we show that NR4A3 protein associates …

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Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

Successful treatment of breast cancer directly correlates with tumor stage and grade at diagnosis. Early diagnosis leads to a five-year relative survival rate of 96.8% as opposed to only a 22.5% five-year survival rate when diagnosed at late stage. Cancer-specific mechanisms need to be extended to enable cancer detection in an individual patient, in particular, the metastatic burden that currently cannot be assessed by conventional imaging. This approach for cancer detection would remove the biases of patient characteristics, permit immediate diagnostic feedback, improve sensitivity for early detection of small metastatic lesions, and be cost effective. Toward this goal, the cancer-specific …

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The Effect Of Optimism On The Relationship Between Religiosity And Spirituality Among Elderly Christians, Matthew West

All ETDs from UAB

Older Americans represent one of the most devout groups of religious people in America, yet research is consistently scarce on how to use this characteristic in mental health interventions. This study uses Ordinary Least Squares regression of a 2004, national sample of older Christian Americans to assess the relationship between private prayer, church attendance, prayer group participation, religious meaning, optimism, and depressive symptomology. Previous work has found a strong positive relationship between religion and health outcomes. The present endeavor goes beyond examining the main effects of such relationships to look at a possible moderating mechanism--optimism. Controlling for demographic variables and …

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Conceptualization Of Cervical Cancer And Screening Experiences Among Zambian Women Attending A Cervical Screening Program, Heather Leah White

All ETDs from UAB

Invasive cervical cancer (ICC) is the second most commonly diagnosed malignancy worldwide, and approximately 85% of the disease burden occurs in underdeveloped countries. In 2006, the Zambian government launched a cervical screening program within primary health clinics using visual inspection with acetic acid (VIA) coupled with immediate treatment via cryotherapy. The objective of this dissertation was to determine whether the VIA screening program is responsive to the needs and concerns of Zambian women in an effort to improve screening uptake, and for human immunodeficiency virus (HIV) positive women who are potentially subject to increased ICC screening and treatment, increase long-term …

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Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

The virus Eastern Equine Encephalitis virus (EEEV) is a highly pathogenic arthropod-borne virus (arbovirus) present in the US. The virus is listed as a reportable illness to the Centers of Disease Control and Prevention (CDC) and is also listed as a select agent by Human Health and Services (HHS). Studies on EEEV starting back in the 1930's have determined many important facets of the ecology, transmission and evolution of the virus. It is understood that in many endemic foci, the mosquito Culiseta melanura is the primary enzootic vector of the virus. EEEV is thus maintained in an enzootic cycle between …

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Pick It Up, Put It Down: A Grounded Theory Study Of How Low Income African American Patients In The Deep South Start Smoking And Quit Smoking, Jessica Hillman Williams

All ETDs from UAB

The purpose of this qualitative was to use data extracted from the narrative stories of African American patients to generate a grounded theory to explain the process and act of initiating and of quitting smoking among low income African American patients in the Deep South. This is important since African Americans are more likely to suffer from smoking-related illnesses, which are the leading cause of death among African Americans. Data were analyzed from interviews conducted in 2005 as part of the Stories Project and supplementary interviews conducted in 2011. Convenience sampling strategies guided participant recruitment for primary interviews and theoretical …

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Efficacy Of Biocides Used In The Modern Food Industry To Control Salmonella Enterica, And Links Between Biocide Tolerance And Resistance To Clinically Relevant Antimicrobial Compounds, Orla Condell, Carol Iversen, Shane Cooney, Karen Power, Ciara Walsh, Catherine Burgess, Seamus Fanning

Articles

Biocides play an essential role in limiting the spread of infectious disease. The food industry is dependent on these agents, and their increasing use is a matter for concern. Specifically, the emergence of bacteria demonstrating increased tolerance to biocides, coupled with the potential for the development of a phenotype of cross-resistance to clinically important antimicrobial compounds, needs to be assessed. In this study, we investigated the tolerance of a collection of susceptible and multidrug-resistant (MDR) Salmonella enterica strains to a panel of seven commercially available food-grade biocide formulations. We explored their abilities to adapt to these formulations and their active …

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Evolutionary History And Spread Of Multidrug Resistant Inchi1 Plasmids In Salmonella Typhi, Kathryn Holt, Minh Duy Phan, Stephen Baker, Pham Thanh Duy, Tran Vu Thieu Nga, Satheesh Nair, Arthur Keith Turner, Ciara Walsh, Seamus Fanning, Sinead Farrell-Ward, Shanta Dutta, François-Xavier Weill, Julian Parkhill, Gordon Dougan, John Wain

Articles

Typhoid fever, infection with Salmonella enterica serovar Typhi (S. Typhi), remains a serious health concern in many parts of the world, particularly where sanitation is poor. While vaccines against S. Typhi are available, coverage in endemic regions is low, leaving antimicrobial therapy central to disease control. Unfortunately, drug resistant S. Typhi emerged in the mid-1970s and multi-drug resistance (MDR) is now a significant problem in many typhoid endemic areas. In the S. Typhi population, MDR is almost exclusively conferred by self-transmissible IncHI1 plasmids carrying a suite of antimicrobial resistance genes. We compared eight IncHI1 plasmid sequences and identified single nucleotide …

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Experiences And Perceptions Of Pregnant Unmarried Adolescent Girls In Nigeria, Priscilla N. Asonye

Walden Dissertations and Doctoral Studies

Sexual activity among unmarried adolescents is a major public health problem in Nigeria, because unmarried pregnant girls are more likely to have multiple sex partners and are less likely to use contraceptives, putting them at greater risk for sexually transmitted diseases (STD), unplanned pregnancy, abortion, social isolation, and poverty. Teen pregnancy and STD rates are on the rise in Nigeria, yet few data exist on the experience of the adolescents themselves. This phenomenological study was designed to explore the in-depth experiences of 10 pregnant, unmarried adolescent girls aged 16-19, including the factors contributing to their sexual activity. An ecological model …

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A Medical Malpractice Model For Developing Countries?, Nathan Cortez

Faculty Journal Articles and Book Chapters

This Article, written for the symposium "Reforming Medical Liability: Global Perspectives," evaluates the unique plight of developing countries in crafting medical liability regimes. Many developing countries struggle to maintain workable systems for adjudicating physician negligence. This is due to a variety of factors, such as widespread poverty, more pressing public health priorities that demand attention, a scarcity of physicians, immature health care systems, large informal health sectors, regulatory deficits, and weak civil societies, among others. Patients in these countries are also less able than their counterparts in well-developed countries to evaluate and challenge the care they receive and thus serve …

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Adverse Publicity By Administrative Agencies In The Internet Era, Nathan Cortez

Faculty Journal Articles and Book Chapters

Nearly forty years ago, Ernest Gellhorn documented the potentially devastating impact that can occur when federal agencies issue adverse publicity about private parties. Based on his article, the Administrative Conference of the United States (ACUS) recommended that courts, Congress, and agencies hold agencies to clear standards for issuing such publicity. In the decades since, some agencies have adopted standards, but most have not. And neither the courts nor Congress has intervened to impose standards. Today, agencies continue to use countless forms of publicity to pressure alleged regulatory violators and to amplify their overall enforcement powers — all without affording due …

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Full-Text Articles in Entire DC Network

Choking Out Local Community Service Organizations: Rising Federal Tax Regulation And Its Impact On Small Nonprofit Entities, Nicole S. Dandridge

Kentucky Law Journal

Spare The Rod, Spoil The Litigator? The Varying Degrees Of Culpability Required For An Adverse Inference Sanction Regarding Spoliation Of Electronic Discovery, Lauren R. Nichols

Kentucky Law Journal

Material Witness Detentions After Al-Kidd, Wesley Macneil Oliver

Kentucky Law Journal

Non-Prisoner Pro Se Litigation In The United States District Court For The Eastern District Of Kentucky: Analyzing 2004 And 2007 Cases From Filing To Termination, Timothy D. Thompson

Kentucky Law Journal

The Effect Of Using E-Learning Tools In Online And Campus-Based Classrooms On Student Performance, Edith Galy, Clara Downey, Jennie Johnson

International Business and Entrepreneurship Faculty Publications

Credit-Monitoring Damages In Cybersecurity Tort Litigation, Vincent R. Johnson

Faculty Articles

Federal Rules Pending Public Comment, David A. Schlueter

Faculty Articles

Conference Program [2011], Georgia International Conference On Information Literacy

Georgia International Conference on Information Literacy

Daoist Elements In Cai Guo-Qiang's Inopportune And Head On, Kelley Wockenfuss

All ETDs from UAB

Role Of Vdr In Host Immune Response To Porphyromonas Gingivalis Infection, Gulam Yezdani

All ETDs from UAB

Piggybac Transposon Mutagenesis In Human And Mouse Stem Cells, Tingting Zhang

All ETDs from UAB

Modeling Incident And Emergency Management From A Regional Perspective, Ozge Cavusoglu

All ETDs from UAB

Limited Transplantation Of Antigen-Expressing Hematopoietic Stem Cells Induces Long-Lasting Cytotoxic T Cell Responses And Effect Of Altered Suppressive Myeloid Population On Hiv-Disease Progression, Warren L. Denning

All ETDs from UAB

Role Of The Cardiomyocyte Circadian Clock In Modulating Myocardial Physiology And Pathophysiology, David Joseph Durgan

All ETDs from UAB

Effects Of Growth Factor Induced Pathways On Differentiation Of The Human Neuronal Cell Line Sh-Sy-5y., Ashish D. Dwary

All ETDs from UAB

From Brown To Bakke: Race Change And The Birmingham City Schools, 1963-1983, Johnmark Allen Edwards

All ETDs from UAB

Ultrasound Elasticity Measurements As A Predictor For Arteriovenous Fistula Maturation, Anna Sorace

All ETDs from UAB

The Effect Of Changes In Tort Laws On Cesarean Section Rates In The United States, Allison Jean Taylor

All ETDs from UAB

Osteogenic Differentiation Of Human Mesenchymal Stem Cells Enhanced By Bone Ecm Analogous Nanomatrix Composites, Jeremy Benton Vines

All ETDs from UAB

Role Of Nr4a3 Nuclear Receptor In Physiological Regulation Of Metabolism, Grace R. Walton

All ETDs from UAB

Strategies For Combined Screening And Imaging Of Breast Cancer, Jason Morgan Warram

All ETDs from UAB

The Effect Of Optimism On The Relationship Between Religiosity And Spirituality Among Elderly Christians, Matthew West

All ETDs from UAB

Conceptualization Of Cervical Cancer And Screening Experiences Among Zambian Women Attending A Cervical Screening Program, Heather Leah White

All ETDs from UAB

Ecology And Transmission Of Eastern Equine Encephalitis Virus In The Southeastern United States, Gregory Scott White

All ETDs from UAB

Pick It Up, Put It Down: A Grounded Theory Study Of How Low Income African American Patients In The Deep South Start Smoking And Quit Smoking, Jessica Hillman Williams

All ETDs from UAB

Efficacy Of Biocides Used In The Modern Food Industry To Control Salmonella Enterica, And Links Between Biocide Tolerance And Resistance To Clinically Relevant Antimicrobial Compounds, Orla Condell, Carol Iversen, Shane Cooney, Karen Power, Ciara Walsh, Catherine Burgess, Seamus Fanning

Articles

Articles

Experiences And Perceptions Of Pregnant Unmarried Adolescent Girls In Nigeria, Priscilla N. Asonye

Walden Dissertations and Doctoral Studies

A Medical Malpractice Model For Developing Countries?, Nathan Cortez

Faculty Journal Articles and Book Chapters

Adverse Publicity By Administrative Agencies In The Internet Era, Nathan Cortez

Faculty Journal Articles and Book Chapters