Digital Commons Network^™

Saliva Test Can Reveal Silent Virus That Steals Babies' Hearing, Jim Bakken

Browse All News

No abstract provided.

Factors Influencing Ectoparasitism On Western Fence Lizards (Sceloporus Occidentalis): Host Sex, Testosterone, Reproductive Condition, And Behavior, Nicholas B. Pollock

Master's Theses

Host-parasite relationships are one of the most common symbiotic relationships present in a diverse array of ecosystems. There are numerous factors that impact the dynamics of these relationships. Major factors that can influence the degree of parasitism include host sex, hormonal state, reproductive condition, and behavior. It has been observed in several vertebrate taxa that males have higher ectoparasite intensities than females and males with increased testosterone have increased ectoparasite intensities. One potential reason for these observations is that testosterone concentrations are elevated in males, particularly during the breeding season, and when circulating concentrations increase males become more vulnerable to …

The Freedom Of Health, Abigail R. Moncrieff

Law Faculty Articles and Essays

This Article first draws out the freedom of health from Supreme Court precedent and demonstrates that, like other substantive constitutional rights, the freedom of health is a negative liberty that must be balanced against legitimate and compelling regulatory projects. The Article then applies that understanding of the freedom to evaluate some proposed and actual health care regulations that have made headline news in the last decade. I consider the constitutionality of the phantom death panels, the HlNl vaccine distribution program, the FDA's restrictions on access to experimental drugs, PPACA's obesity and smoking regulations, and, of course, PPACA's individual mandate. Should …

Acute Vertebral Compression Fracture: Differentiation Of Malignant And Benign Causes By Diffusion Weighted Magnetic Resonance Imaging, Fatima Mubarak, Waseem Akhtar

Department of Radiology

OBJECTIVE: To evaluate the sensitivity, specificity and accuracy of diffusion weighted (DWI) magnetic resonance imaging (MRI) in the diagnosis and differentiation between benign (osteoporotic/infectious) and malignant vertebral compression fractures in comparison with histology findings and clinical follow up.

METHODS: The study was conducted at the Radiology Department, Aga Khan University Hospital (AKUH) Karachi. It was a one year cross-sectional study from 01/01/2009 to 01/01/2010. Forty patients with sixty three vertebral compression fractures were included. Diffusion-weighted sequences and apparent diffusion coefficient (ADC) images on a 1.5 T MR scanner were obtained in all patients to identify the vertebral compression fracture along …

Enseñanza De La Medicina Tropical Mediante La Discusión De Casos Clínicos [Teaching Tropical Medicine Through Discussion Of Clinical Cases], Pedro Navarro, Luis Alfonso Colmenares Suárez, Albany Sosa, María Soto, Nathalie Chacon, Isabel Trebesch, María Antonia De La Parte, Amando Martin

Physician Assistant Studies Faculty Publications

Introducción: En los últimos años se han propuesto cambios en la enseñanza de la medicina tropical, basando la docencia en el estudiante. Objetivo: Utilizar la metodología de la discusión organizada y razonada de casos clínicos, con la participación activa del estudiante, a in de llegar a un diagnóstico presuntivo de las patologías presentadas.

Metodología: Se describe el proceso de discusión con los estudiantes de medicina tropical, de cinco pacientes con enfermedades infecciosas bacterianas (iebre tifoidea, brucelosis, leptospirosis, cólera y shigellosis), diagnosticados y tratados en la Consulta de Endemias Rurales del Instituto de Medicina Tropical y en los Servicios de …

The Spread Of Antibiotic-Resistant Bacteria Through Medical Tourism And Transmission Prevention Under The International Health Regulations, Tamara L. Hill

Chicago Journal of International Law

Medical tourism-travel by healthcare patients to a foreign location for medical treatment-is a growing industry. Healthcare is nationally regulated in eveU county, and difficulties arise where legal remedies and standards vary between a medical tourist's resident and destination county. Antibiotic-resistant bacteria, which are typically limited to healthcare settings and close community quarters, have predictable risk factors. These predictable risk factors generally reduce concern regarding healthcare-associated strains in the medical community because hospitals can set admission and contact policies to reduce the spread of healthcare-associated strains. As medical tourism increases, however, the spread of healthcare-associated antibiotic-resistant bacteria infections is also likely …

Rrh Library Newsletter, June 2011, Libraries At Rochester Regional Health

Rochester Regional Health authored publications and proceedings

Newsletter sections include: Bed Bugs (Cimex lectularius); Summer Book Sale

Characterization Of A Pdms Microfluidic Reactor For Synthesizing Quantum Dots, Brian Harley

Materials Engineering

A PDMS microfluidic reactor was made in Cal Poly’s class 1000 clean room for the purpose of synthesizing quantum dots.  The device master mold was made from a silicon substrate and SU-8 features 50μm tall.  The PDMS reactor was cast from that mold.  The flow rates of fluid through the channels, heating of the reactor and pressure in the reactor were measured in order to characterize the potential for synthesizing quantum dots.  Flow rates of 20 mL/hr through 4 mL/hr were tested to characterize the consistency of amount of time the fluid remains in the reactor at a constant flow …

Prohibiting Medical Method Patents: A Criticism Of The Status Quo, Mark S. Wilke

Canadian Journal of Law and Technology

Methods of medical treatment are not patentable in Canada. This means that inventions involving the performance of surgery, administration of medicine, or extraction of fluids or tissue for diagnostic tests cannot directly be protected under the current patent regime. However, this prohibition is not an absolute ban. Many medical innovations are patentable, including surgical tools and devices, drugs and other chemical compounds, medical “uses”, diagnostic assays and methods of treat- ing “natural” conditions. The practical reality is that the distinction between what is and what is not patentable is poorly defined. This uncertainty presents a steep challenge for inventors and …

Importance Of Proper Diagnosis For Management: Multifocal Choroiditis Mimicking Ocular Histoplasmosis Syndrome., Elham Hatef, Peykan Turkcuoglu, Mohamed Ibrahim, Yasir J. Sepah, Matthew Shulman, Jangwon Heo, Jeong H. Lee, Roomasa Channa, Afsheen Khwaja, Zubir Rentiya, Syed Mahmood Shah, Diana V. Do, Quan Dong Nguyen

Journal Articles: Ophthalmology

PURPOSE: The study aims to evaluate a series of patients with initial diagnosis of ocular histoplasmosis syndrome (OHS) with progression and response to treatments consistent with multifocal choroiditis (MFC).

METHODS: Retrospective review of nine patients referred for management of recurrent OHS lesions. Serology panel was conducted to rule out autoimmune and infectious causes.

RESULTS: Clinical examination revealed multiple small, punched-out peripheral chorioretinal scars, and peripapillary atrophy. Histoplasma antigen/antibody was negative in all patients. Fluorescein angiography and optical coherence tomography confirmed active inflammation in five patients. Immunomodulatory therapy (IMT) was initiated to control active inflammation. While on IMT, visual acuity stabilized …

Immune Evasion Of Porcine Reproductive And Respiratory Syndrome Virus Through Glycan Shielding Involves Both Glycoprotein 5 As Well As Glycoprotein 3, Hiep Vu, Byungjoon Kwon, Kyoung-Jin Yoon, William W. Laegreid, Asit K. Pattnaik, Fernando A. Osorio

School of Veterinary and Biomedical Sciences: Faculty Publications

Passive administration of porcine reproductive and respiratory syndrome virus (PRRSV) neutralizing antibodies (NAbs) can effectively protect pigs against PRRSV infection. However, after PRRSV infection, pigs typically develop a weak and deferred NAb response. One major reason for such a meager NAb response is the phenomenon of glycan shielding involving GP5, a major glycoprotein carrying one major neutralizing epitope. We describe here a type II PRRSV field isolate (PRRSV-01) that is highly susceptible to neutralization and induces an atypically rapid, robust NAb response in vivo. Sequence analysis shows that PRRSV-01 lacks two N-glycosylation sites, normally present in wild-type (wt) PRRSV strains, …

A Chip Off The Old Block: Familial Dna Searches And The African American Community, Brett Mares

Minnesota Journal of Law & Inequality

No abstract provided.

Urbanization, Obesity, And The Protective Effect Of Traditional Food Behaviors In Fiji, Danielle Christine Krause

Social Sciences

No abstract provided.

Oxidation Kinetics Of Silver Thin Films For Antimicrobial Applications In The Health Care Industry, Sean D. Morham

Materials Engineering

To determine if varying city water qualities from around the United States can support a developing “oxidation corrosion of silver thin films” method of creating aqueous ionic silver solutions for the anti-microbial treatment of healthcare linens, a test was devised holding all variables constant with the exception of water quality parameters. This corrosion style test was done in order to assess a pass/fail criteria of 25 ppb ionic silver concentration in the aqueous solutions which resulted from the corrosion of silver thin film coated substrates. Above 25 ppb being a pass, below 25 ppb being a fail. While varying the …

The Effects On Population Health Status Of Using Dedicated Property Taxes To Fund Local Public Health Agencies, Peggy A. Honoré, Xueyuan Wang

Faculty Publications

Background: In the United States, a dedicated property tax describes the legal authority given to a local jurisdiction to levy and collect a tax for a specific purpose. We investigated for an association of locally dedicated property taxes to fund local public health agencies and improved health status in the eight states designated as the Mississippi Delta Region.

Methods: We analyzed the difference in health outcomes of counties with and without a dedicated public health tax after adjusting for a set of control variables using regression models for county level data from 720 counties of the Mississippi Delta …

Fertilization Narratives In The Art Of Gustav Klimt, Diego Rivera And Frida Kahlo: Repression, Domination And Eros Among Cells, Scott F. Gilbert, S. Brauckmann

Biology Faculty Works

Fertilization narratives are powerful biological stories that can be used for social ends, and 20th-century artists have used fertilization-based imagery to convey political and social ideas. In Danae, Gustav Klimt used an esoteric stage of early human embryos to indicate successful fertilization and the inability of government repression to stifle creativity. In Man, Controller of the Universe, Diego Rivera painted a mural of a man controlling an ovulating ovary, depicting Trotsky's view that society will rationally regulate human fertilization. His former wife, Frida Kahlo, refuted this view in Moses: Nucleus of Creation, wherein she painted images of fertilization and embryo …

Prevalence Of Myxobolus Cerebralis Infections Among Genetic Lineages Of Tubifex Tubifex At Three Locations In The Madison River, Montana, Nilanjan Lodh, Lori Stevens, Billie Kerans

Clinical Lab Sciences Faculty Research and Publications

Host biodiversity can impact disease risk and influence the transmission of parasitic disease. Stream sediment–dwelling worms, Tubifex tubifex (Clitellata: Oligochaeta), are the definitive host of the parasite Myxobolus cerebralis (Myxozoa: Myxosporea), which causes whirling disease in salmonid fishes. Genetic diversity of T. tubifex is correlated with host susceptibility to M. cerebralis, and mitochondrial Lineage III is generally shown to be more likely to be infected and produce the triactinomyxon (TAM) spores than other lineages. We determined the mitochondrial lineage, relative abundance, and prevalence of infection of T. tubifex collected at 3 sites in the Madison River, Montana, where previous …

An Efficient Primer Selection Process Combining Progressive And Iterative Multiple Sequence Alignment Strategies: Clustalw And Hmmer, Michael C. Green

Master's Theses

This thesis describes a method for using a computationally efficient algorithm to identify candidate DNA primer sequences. DNA sequencing primers are a critical element of polymerase chain reaction (PCR) and DNA sequence analysis.  A variety of methods for deriving DNA primers exist, but such methods are often computationally intensive, or do not use available sequence data that could potentially serve as a possible resource for primer identification.  Though no current algorithm exists which will always yield a correct primer for every need, evaluation of multi-sequence alignments may provide a reliable source for primer candidates.  However, an exact mathematical solution for …

Optimizing Micronutrient Intake Of Lactating Women In Kwazulu-Natal, South Africa, Through Increased Wild Edible Plant Consumption, Kerry Pearson

Master's Theses

OPTIMIZING MICRONUTRIENT INTAKE OF LACTATING WOMEN IN KWAZULU-NATAL, SOUTH AFRICA, THROUGH INCREASED WILD EDIBLE PLANT CONSUMPTION

Kerry Pearson

Micronutrient consumption in KwaZulu-Natal, South Africa, is insufficient to meet the needs of lactating women.  Inadequate intake negatively impacts the health of both the mother and infant.  Increasing consumption of wild edible plants has been recommended to combat these deficiencies, but information has not yet been provided on which types of wild plants should be eaten or in what quantity.  The objective of this study was to determine the optimal mixture of wild edible plants that needs to be consumed to meet …

Turfgrass Management At Your Fingertips: Information Delivered Through "Smart" Phone Technology, Patrick E. Mccullough, F Clint Waltz Jr, William Hudson, Alfredo D. Martinez-Espinoza

Journal of Extension

Turfgrass managers and Extension professionals often require real-time, in-situ pest diagnosis, management, and recommendations. Advanced "smart" phones have become important tools for industry professionals and allow flexibility while traveling or away from the office. We have developed an application (app) for iPhone® and Blackberry® "smart phones" that allows access to a library of resources in the field. The Turfgrass Management application contains a full suite of weed, disease, insect, and turfgrass species resources. More than 2,500 subscriptions from over 30 countries have been downloaded. We present evidence of the usefulness of delivery of information through this mobile technology.

Assessing The Need For An On-Line Educational Module For Volunteer Leaders On Bio-Security In Washington State 4-H Livestock Projects, Jill L. Stevenson, Dale A. Moore, Jerry Newman, Janet L. Schmidt, Sarah M. Smith, Jean Smith, Susan Kerr, Michael Wallace, Pat Boyes

Journal of Extension

4-H livestock projects present disease transmission risks that can be reduced by the use of bio-security practices. The responsibility of teaching bio-security to youth belongs primarily to volunteer leaders, who may not be aware of the importance of these practices. A needs assessment for an online educational module about bio-security revealed that existing materials are inconsistent, are not directed at this audience, and are not being used by leaders. Although barriers to online education exist, there are many benefits of online education that can be passed from leaders to youth to help reduce the spread of disease in 4-H livestock.

Resource Maps For Fresh Meat Across Retail And Wholesale Supply Chains, Peter Whitehead, Martin Palmer, Carlos Mena, Adrian Williams, Christine Walsh

Business Faculty Publications and Presentations

Consumers spend more money on meat than any other food item. WRAP has already shown that households are wasting around 570,000 tonnes of fresh meat each year, of which 260,000 (46%) is avoidable with a value of about £1,300M. These wasted products also include embedded water and embedded carbon. This research has focused on the supply of meat from the farm gate onwards, including livestock slaughtering, meat preparation, processing and packaging, distribution and retail. It focuses on fresh meat from the four animal species which comprise some 96% by weight of all animals slaughtered for human consumption, namely chickens, cattle, …

Emmett Oliver's Story: Psycho-Social Development Of An Extraordinary Native American, Susanna A. Hayes

Online Readings in Psychology and Culture

Emmett Oliver's life story offers clear evidence that human resilience originates in a combination of many aspects of personality traits, abilities and interests, and supportive social relationships. Living in an era when many of his Native peers did not develop their talents or find a meaningful place in their rapidly changing cultures, Emmett pursued an education. He became a teacher, a Coast Guard Commander, a counselor, and an educational policy maker. His achievements severed to bolster his motivation when he felt drawn to a less challenging work.

Tim-3 Negatively Regulates Il-12 Expression By Monocytes In Hcv Infection, Ying Zhang, Cheng J. Ma, Jia M. Wang, Xiao J. Ji, Xiao Y. Wu, Zhan S. Jia, Jonathan P. Moorman, Zhi Q. Yao

ETSU Faculty Works

T cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) is a newly identified negative immunomodulator that is up-regulated on dysfunctional T cells during viral infections. The expression and function of Tim-3 on human innate immune responses during HCV infection, however, remains poorly characterized. In this study, we report that Tim-3 is constitutively expressed on human resting CD14+ monocyte/macrophages (M/MØ) and functions as a cap to block IL-12, a key pro-inflammatory cytokine linking innate and adaptive immune responses. Tim-3 expression is significantly reduced and IL-12 expression increased upon stimulation with Toll-like receptor 4 (TLR4) ligand - lipopolysaccharide (LPS) and TLR7/8 ligand …

Chronic Granulomatous Disease: A Review Of The Infectious And Inflammatory Complications, Eunkyung Song, Gayatri B. Jaishankar, Hana Saleh, Warit Jithpratuck, Ryan Sahni, Guha Krishnaswamy

ETSU Faculty Works

Chronic Granulomatous Disease is the most commonly encountered immunodeficiency involving the phagocyte, and is characterized by repeated infections with bacterial and fungal pathogens, as well as the formation of granulomas in tissue. The disease is the result of a disorder of the NADPH oxidase system, culminating in an inability of the phagocyte to generate superoxide, leading to the defective killing of pathogenic organisms. This can lead to infections with Staphylococcus aureus, Psedomonas species, Nocardia species, and fungi (such as Aspergillus species and Candida albicans). Involvement of vital or large organs can contribute to morbidity and/or mortality in the affected patients. …

May 30, 2011 Reporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Shared Benefits From Exposing Research Data, Malcom Wolski, Joanna Richardson, Robyn Rebollo

Proceedings of the IATUL Conferences

No abstract provided.

Profound Early Control Of Highly Pathogenic Siv By An Effector Memory T-Cell Vaccine., Scott G. Hansen, Julia C. Ford, Matthew S. Lewis, Abigail B. Ventura, Colette M. Hughes, Lia Coyne-Johnson, Nathan Whizin, Kelli Oswald, Rebecca Shoemaker, Tonya Swanson, Alfred W. Legasse, Maria J. Chiuchiolo, Christopher L. Parks, Michael K. Axthelm, Jay A. Nelson, Michael A. Jarvis, Michael Piatak, Jeffrey D. Lifson, Louis J. Picker

School of Biomedical Sciences

The acquired immunodeficiency syndrome (AIDS)-causing lentiviruses human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) effectively evade host immunity and, once established, infections with these viruses are only rarely controlled by immunological mechanisms. However, the initial establishment of infection in the first few days after mucosal exposure, before viral dissemination and massive replication, may be more vulnerable to immune control. Here we report that SIV vaccines that include rhesus cytomegalovirus (RhCMV) vectors establish indefinitely persistent, high-frequency, SIV-specific effector memory T-cell (T(EM)) responses at potential sites of SIV replication in rhesus macaques and stringently control highly pathogenic SIV(MAC239) infection early after …

Climate Change And Climate Variability: Personal Motivation For Adaptation And Mitigation, Jan C. Semenza, George B. Ploubidis, Linda Acha George

Environmental Science and Management Faculty Publications and Presentations

Background: Global climate change impacts on human and natural systems are predicted to be severe, far reaching, and to affect the most physically and economically vulnerable disproportionately. Society can respond to these threats through two strategies: mitigation and adaptation. Industry, commerce, and government play indispensable roles in these actions but so do individuals, if they are receptive to behavior change. We explored whether the health frame can be used as a context to motivate behavioral reductions of greenhouse gas emissions and adaptation measures. Methods: In 2008, we conducted a cross-sectional survey in the United States using random digit dialing. Personal …

Pcr Amplification Of Trypanosoma Cruzi - Specific Dna From Raccoon Blood Samples, Colin Moss

Mahurin Honors College Capstone Experience/Thesis Projects

The parasitic protist Trypanosoma cruzi is the causative agent of Chagas Disease. Chagas Disease causes greater than 15,000 deaths each year, and nearly 28 million people are believed to be at risk of infection in Central and South America. This parasite has been described in many mammalian host species and has also been described in the United States. The purpose of this study was to attempt to use PCR to amplify T. cruzi-specific DNA directly from blood samples obtained from raccoons (Procyon lotor) trapped in Warren and Barren Counties of Kentucky in 2007 and 2008. DNA was …