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Cardiac Output Is Not Related To The Slowed O2 Uptake Kinetics In Type 2 Diabetes, Oscar Mac Ananey, J Malone, S Warmington, D O'Shea, S Green, M Egana

Articles

Abstract

PURPOSE:

This study aimed to investigate whether cardiac output (CO) responses were related to VO2 kinetics during cycling in type 2 diabetes.

METHODS:

A total of 9 middle-aged women with uncomplicated type 2 diabetes, 9 nondiabetic overweight women, and 11 nondiabetic lean women were recruited. Initially, the ventilatory threshold (VT) and peak VO2 were determined during a maximal graded test. Then, on two separate days, subjects completed three 7-min bouts of constant-load cycling at each of three intensities: 50% VT, 80% VT, and midpoint between VT and peak VO2 (50% Δ). CO (inert gas rebreathing) was recorded at 30 …

Evaluation Of Activated Partial Thromboplastin Time (Aptt) Reagents For Application In Biomedical Diagnostic Device Development, Magdalena Dudek, Leanne F. Harris, Anthony J. Killard

Articles

Introduction: The most commonly used test for monitoring heparin therapy is the activated partial thromboplastin time (aPTT). The response of available aPTT reagents to heparin varies significantly. The aim of this study was to highlight the differences between aPTT reagents stored in a dried format to select the most suitable formulations to be used for the development of point-of-care diagnostic devices used for monitoring of unfractionated heparin dose response. Methods: Ten reagents were analysed in terms of their performance in liquid and in dried form after storage for 24 h and 14 days. Performance was assessed by measurement of the …

A Catholic Reformations Of Manners, Lisa Clark Diller

Faculty Works

No abstract provided.

Complete Genome Sequence Of Treponema Paraluiscuniculi, Strain Cuniculi A: The Loss Of Infectivity To Humans Is Associated With Genome Decay, David Smajs, Marie Zobaníková, Michal Strouhal, Darina Cejková, Shannon Dugan-Rocha, Petra Pospíšilová, Steven J Norris, Tom Albert, Xiang Qin, Kym Hallsworth-Pepin, Christian Buhay, Donna M Muzny, Lei Chen, Richard A Gibbs, George M Weinstock

Faculty, Staff and Student Publications

Treponema paraluiscuniculi is the causative agent of rabbit venereal spirochetosis. It is not infectious to humans, although its genome structure is very closely related to other pathogenic Treponema species including Treponema pallidum subspecies pallidum, the etiological agent of syphilis. In this study, the genome sequence of Treponema paraluiscuniculi, strain Cuniculi A, was determined by a combination of several high-throughput sequencing strategies. Whereas the overall size (1,133,390 bp), arrangement, and gene content of the Cuniculi A genome closely resembled those of the T. pallidum genome, the T. paraluiscuniculi genome contained a markedly higher number of pseudogenes and gene fragments (51). In …

Alterations In Content And Localization Of Defensins In Rat Ileum And Jejunum Following Ischemia-Reperfusion Specific Peptides, In Specific Places, For Specific Jobs?, Rosemary A Kozar, Rachel J Santora, Brian J Poindexter, Stephen M Milner, Roger J Bick

Faculty, Staff and Student Publications

Objective: To determine alterations in quantities and distributions of natural antimicrobials following ischemia-reperfusion injury. We hypothesized that these compounds would be upregulated in areas of small intestine where changes in permeability and cellular disruption were likely and where protective mechanisms would be initiated. Methods: Rats with ischemia-reperfusion underwent superior mesenteric artery clamping and reperfusion. Shams were subjected to laparotomy but no clamping. Ileum and jejunum were harvested and sectioned, and subjected to fluorescence deconvolution microscopy for determinations of content and localization of rat beta defensins, 1, 2, 3; rat neutrophil protein-1; and cathelicidin LL-37. Modeling was performed to determine cellular …

Association Of Retinoic Acid Receptor Genes With Meningomyelocele, Phong X Tran, Kit Sing Au, Alanna C Morrison, Jack M Fletcher, Kathryn K Ostermaier, Gayle H Tyerman, Hope Northrup

Faculty, Staff and Student Publications

BACKGROUND: Neural tube defects (NTDs) occur in as many as 0.5-2 per 1000 live births in the United States. One of the most common and severe neural tube defects is meningomyelocele (MM) resulting from failed closure of the caudal end of the neural tube. MM has been induced by retinoic acid teratogenicity in rodent models. We hypothesized that genetic variants influencing retinoic acid (RA) induction via retinoic acid receptors (RARs) may be associated with risk for MM.

METHODS: We analyzed 47 single nucleotide polymorphisms (SNPs) that span across the three retinoic acid receptor genes using the SNPlex genotyping platform. Our …

Immunopathology Of Postprimary Tuberculosis: Increased T-Regulatory Cells And Dec-205-Positive Foamy Macrophages In Cavitary Lesions, Kerry J Welsh, Semyon A Risin, Jeffrey K Actor, Robert L Hunter

Faculty, Staff and Student Publications

Postprimary tuberculosis occurs in immunocompetent people infected with Mycobacterium tuberculosis. It is restricted to the lung and accounts for 80% of cases and nearly 100% of transmission. Little is known about the immunopathology of postprimary tuberculosis due to limited availability of specimens. Tissues from 30 autopsy cases of pulmonary tuberculosis were located. Sections of characteristic lesions of caseating granulomas, lipid pneumonia, and cavitary stages of postprimary disease were selected for immunohistochemical studies of macrophages, lymphocytes, endothelial cells, and mycobacterial antigens. A higher percentage of cells in lipid pneumonia (36.1%) and cavitary lesions (27.8%) were positive for the dendritic cell marker …

A Statement On Biblical Spirituality, Seventh-­Day Adventist Theological Seminary

Books

We believe that the greatest and most urgent of all our needs is a revival of true godliness, which is true biblical spirituality, or having Christ formed in us by the Holy Spirit (Gal 4:19; Col 1:27). Such spirituality is not natural to the sinful person who regards it as foolishness: “The natural man does not receive the things of the Spirit of God” (1 Cor 2:14). A vital part of discipleship and the training of gospel workers at the Seventh-­‐ day Adventist Theological Seminary is to enable them to cultivate genuine biblical spirituality through justification and the process of …

Principles Of Worship And Liturgy, Fernando Canale

Perspective Digest

No abstract provided.

Relating To The Bible (Part 2), Roy Gane

Perspective Digest

No abstract provided.

The Traditional Model, Steve Case

180 Symposium Publications

No abstract provided.

Youth Camp Meeting Ministry Is Alive And Growing, Benjamin Lundquist

180 Symposium Publications

No abstract provided.

Artists In Christian Expression (Ace), Diane Helbley

180 Symposium Publications

No abstract provided.

Sabbath And Sanctification, Roy E. Gane

Journal of the Adventist Theological Society

No abstract provided.

The Validity Of The Levitical Food Laws Of Clean And Unclean Animals: A Case Study Of Biblical Hermeneutics, Jiri Moskala

Journal of the Adventist Theological Society

No abstract provided.

The Validity Of The Levitical Food Laws Of Clean And Unclean Animals: A Case Study Of Biblical Hermeneutics, Jiri Moskala

Faculty Publications

No abstract provided.

In The News, Joe N. Caudell

Human–Wildlife Interactions

No abstract provided.

Graduate Recital Program Notes, Emily Cline

Research Papers

This document introduces Robert Schumann’s Liederkreis Heine, Op. 24 Nos. 1,4,5,6,and 9, Marina’s Aria from Boris Godunov by Modest Musorgsky, Siete Canciones Populares Españolas by Manuel de Falla, Airs Chantés by Francis Poulenc, and Songs from Letters by Libby Larsen. Each of these works is presented with a brief history of composer as well as relevant historical context and information regarding the origins of the texts. A short analysis of both text and music completes each chapter.

The New Climate Metric: The Sustainable Corporation And Energy, Steven Ferrey

Suffolk University Law School Faculty Works

The globalization of commerce is manifest. The modern mission statement of many US corporations is to compete in global markets. In this article, first, we define what is “sustainable” in the modern corporate context. Like other new terms employed in recent government environmental regulations, such as “additionality” (see S. Ferrey, When 1 + 1 No Longer Equals 2: The New Math of Legal "Additionality" Controlling World and U.S. Global Warming Regulation, 10 MINN. J.L. SCI. & TECH. 591 (2009)), the reality may be in the "eye of the beholder" – or at least, the regulator. This article examines measurement …

Dermal Reduction Of Urushiols Using An Activated Charcoal Formulated Dermal Care Patch, Celena Cameron

Honors Theses

For centuries, activated Charcoal (AC) has been used externally in a poultice form to adsorb "poisons" trapped in the outer layers of skin and internally to relieve intestinal discomfort and to remove toxic materials. The largest use for activated charcoal, in our society, is as a filter bed in air and water remediation cartridges. Recently, scientists have formulated AC into a nonstick dermal bandage called the Charcoal Patch (CP), but the adsorption properties are not well understood for this new formulation. Experiments have been conducted to see if these dermal bandages can be used to adsorb oils such as poison …

Synthesis And Testing Of Second Generation Azatilbenes, Maurice Hardy

Honors Theses

Based on previous research, azastilbenes have been reported as effective chemical sensors for organophosphates and organothiophosphates; they are related classes and the active components of agricultural pesticides, environmental pollutants and chemical warfare agents. This project builds on previous work and involves the synthesis of a variety of these azastilbenes and the testing of their respective properties. Azastilbene sensors are prepared using high-yield organic synthetic methodology developed in Professor Murray's lab. The next step involves testing the sensors through a measure, by UV-Vis spectroscopy and fluorometry, of an optical change upon the addition of analyte to a solution containing azastilbene sensor.

The Effects Of Valproate Prodrugs On The Inositol Biosynthetic Pathway In Saccharomyces Cerevisiae Yeast, Lisa Thompson

Honors Theses

Bipolar disorder is a psychiatric disorder characterized by episodes of abnormally elevated mood followed by periods of extreme depression. Currently, valproate is one of the drugs used to treat the disorder but it is associated with many negative side effects. The goal of this project is to create a prodrug with structural similarities to valproate and determine if its effect on growth of the yeast Saccharomyces cerevisiae is similar to that of valproate. Yeast cells were grown in media with or without the prodrug in the presence or absence of inositol. The results showed that the prodrug inhibited growth.

The Important Role And Benefits Of Academic Research In Musical Interpretation: An Application To The Performance Study Of Modest Mussorgsky's Pictures At An Exhibition, Denny Hong

Honors Theses

The ultimate duty of a performing musician is to share a transcendental experience of aural artwork with society. Before doing so, the musician is obligated to conduct thorough research on the cultural, historical, and artistic components of the repertoire in order to create a holistic picture that can then be used to shape a convincing and thoughtful interpretation. My study explores and analyzes the creative tools and analytical methods involved in musical interpretation as applied to my own personal interpretation of Modest Mussorgsky's Pictures at an Exhibition through public performance. My goal is to validate the multifaceted benefits that research …

The Tyrant And The Rogue: Political Implications Of Redemption In William Shakespeare's The Winter's Tale, Jonathan Barrett Koch

Honors Theses

Starting with the negative behavior exhibited by Leontes and Autolycus, this paper traces the process of redemption through the experiences of both characters, considering material both from the play and the Stratford production. The political and civic effects of Leontes‘ tyranny will be contrasted with Autolycus‘ roguery, followed by a comparison of the various agents of redemption. These characters and the offers of redemption they make have a profound effect on their respective redemptions, but only so far as Leontes and Autolycus receive them. The paper closes with a discussion of the results of the redemptions, and the interrelated meaning …

Apocalyptic And Free Will, Robert M. Johnston

Journal of the Adventist Theological Society

No abstract provided.

Interpretation Of Bere’ Ît In The Context Of Genesis 1:1-3, Jiří Moskala

Andrews University Seminary Studies (AUSS)

No abstract provided.

Wait! That's Not What We Meant By Civil Society!: Questioning The Ngo Orthodoxy In West Africa, Thomas A. Kelley Iii

Faculty Publications

No abstract provided.

Judicial Takings, Judicial Speech, And Doctrinal Acceptance Of The Model Of The Judge As Political Actor, William P. Marshall

Faculty Publications

No abstract provided.

In The News, Joe N. Caudell

Human–Wildlife Interactions

No abstract provided.

When To Research Is To Reveal: The Growing Threat To Attorney And Client Confidentiality From Online Tracking, Anne Klinefelter

Faculty Publications

No abstract provided.