Digital Commons Network^™

Kenyon Collegiate - November 2, 2011

Kenyon Collegiate

No abstract provided.

Ghrelin Receptor Deficiency Does Not Affect Diet-Induced Atherosclerosis In Low-Density Lipoprotein Receptor-Null Mice, Kirk M. Habegger, Erin Grant, Paul Thomas Pfluger, Diego Perez-Tilve, Alan Daugherty, Dennis Bruemmer, Matthias H. Tschöp, Susanna M. Hofmann

Saha Cardiovascular Research Center Faculty Publications

OBJECTIVE: Ghrelin, a stomach-derived, secreted peptide, and its receptor (growth hormone secretagogue receptor, GHSR) are known to modulate food intake and energy homeostasis. The ghrelin system is also expressed broadly in cardiovascular tissues. Since ghrelin has been associated with anti-inflammatory and anti-atherogenic properties, but is also well known to promote obesity and impair glucose metabolism, we investigated whether ghrelin has any impact on the development of atherosclerosis. The hypothesis that endogenous ghrelin signaling may be involved in atherosclerosis has not been tested previously.

METHODS AND RESULTS: We crossed ghrelin receptor knockout mice (GHSr^-/-) into a low-density lipoprotein receptor-null …

The Guardian, November 2, 2011, Wright State University Student Body

The Guardian Student Newspaper

Twelve page issue of The Guardian, the official student-run newspaper for Wright State University. The Guardian has been published regularly since March of 1965.

The Spinnaker [Vol. 33 No. 75], University Of North Florida

Spinnaker

Student newspaper for the UNF community.

Maternal, Neonatal And Feeding Type Factors Associated With Severity Of Necrotizing Enterocolitis, Cheryl Ann Miner

Theses and Dissertations

Objective: To identify statistical associations with necrotizing enterocolitis (NEC) severity as dichotomized into cases with Bell stage II and III disease.
Study Design: We conducted a retrospective study using eight consecutive years of data from a multihospital healthcare system analyzed NEC severity (Bell stage II vs. III).
Results: We identified 220 neonates with stage ≥ II who had 225 separate episodes of NEC (157 stage II and 68 stage III). Those with stage III were born at earlier gestational age (P<0.0001) and lower birth weight (P<0.0001). Diagnosis of NEC occurred on about the same day of life in stage II and stage III cases. Those who developed stage III had significantly higher C-reactive protein (P<0.0001), I/T ratio (P= 0.0005), mean platelet volume (MPV) (P= 0.0001) and lower pH (P<0.0001) and platelet counts (P<0.0001). Transfusions were more common to those who progressed to stage III (P<0.0001). Regression analysis indicated higher odds of stage III in relationship to the volume of RBC transfusions (OR 2.41, {CI 1.85 to 3.11}, P<0.0001) and pasteurized human milk (PHM) (OR 1.32, {CI 1.07 to 1.62}, P = 0.0089). In contrast, feeding early mother's own milk (colostrum) for five days reduced the odds for stage III (OR 0.802, {CI 0.67 to 0.96}, P=0.0170). Those with small bowel resection were less likely to have received mother's own milk before NEC (OR 0.94, {CI 0.89 to 0.99}, P = 0.019) and factors predicting death from NEC were a low pH (OR 2.21, {CI 1.27 to 3.85}, P = 0.0005) and less colostrum (OR 0.96, {CI 0.94 to 0.99}, P = 0.003).
Conclusions: RBC transfusions and PHM increased the odds for stage III NEC, whereas early mother's own milk five days …

Cassava Pulp As A Biofuel Feedstock Of An Enzymatic Hydrolysis Proces, Djuma’Ali Djuma’Ali, Nonot Soewarno, Sumarno Sumarno, Dyah Primarini, Wahono Sumaryono

Makara Journal of Technology

Cassava pulp, a low cost solid byproduct of cassava starch industry, has been proposed as a high potential ethanolic fermentation substrate due to its high residual starch level, low ash content and small particle size of the lignocellulosic fibers. As the economic feasibility depends on complete degradation of the polysaccharides to fermentable glucose, the comparative hydrolytic potential of cassava pulp by six commercial enzymes were studied. Raw cassava pulp (12% w/v, particle sizeμm) hydrolyzed by both commercial pectinolytic (1) and amylolytic (2) enzymes cocktail, yielded 70.06% DE. Hydrothermal treatment of cassava pulp enhanced its susceptibility to enzymatic cleavageas compared to …

The Evolution And Future Of E-Books: A Major Shift In Technology, Sean F. O'Connor, Fitzpatrick O'Connor Mr.

Research Papers

Since their creation in 1971 by Michael Hart, e-books have steadily progressed into a major part of our technological landscape through the diffusion of innovations. The technology of e-books and e-readers has only further progressed into the current media landscape of how we read books. The e-book and e-reader technology will only continue at a more rapid pace of heavily impacting the future of book reading exponentially with further adaption of this technology.

Phylogenomic-Based Case Study: An Undergraduate Research Pedagogy At Kentucky State University, The Only Historically Black College And University In The Commonwealth Of Kentucky, Narayanan Rajendran, William Mazhawidza

Journal of Excellence in College Teaching and Learning

Currently the undergraduate biology curriculum at 2 and 4-year colleges especially in Historically Black Colleges and Universities (HBCUs) is undergoing a facelift by implementing a range of recommendations of committees on education. This has produced a demand to educate and train the current and future generation of undergraduates as scientists capable to perform modern biological research that is heavily dependent on genomic training, such as phylogenomics. It is our observation that the HBCUs may not have a strong infrastructure enough to meet this challenge without the development of vigorous research-based learning programs to complement the traditional lecture-only based configuration. In …

Fall/Winter 2011, Full Issue

The Confluence (2009-2020)

No abstract provided.

The Bates Student - Volume 141 Number 04 - November 1, 2011, Bates College

The Bates Student

No abstract provided.

Mentoring Directors As A Strategy To Improve Quality In Early Childhood Programs, Mccormick Center For Early Childhood Leadership

McCormick Center for Early Childhood Leadership Publications

Mentoring and coaching are well established professional development strategies. These relationship-based strategies are often used in conjunction with traditional instructional practices. Most research in this area, however, has focused on the use of mentoring or coaching with teachers to improve teaching practices. This evaluation study conducted for the Ontario Government was designed to determine the extent to which the Mentoring Pairs for Child Care Project achieved its primary goal of enhancing quality in early learning programs in Ontario, Canada by increasing the administrative knowledge and skills of center directors (supervisors).

Daily Announcements November 2011, Wofford College. Office Of Marketing And Communications

Communications Office Daily Announcements

No abstract provided.

Vascular And Mechanical Changes In Bone In Response To Chronic Ischemia And Mechanical Loading, Michael Govea

Master's Theses

Peripheral artery disease (PAD) and osteoporosis have recently been shown to be associated; with the parallel occurrence suggesting that PAD related ischemia may cause or enhance the onset of osteoporosis. In order to determine the mechanism linking osteoporosis and PAD this paper will examine the effects of ischemia and mechanical stimulation on bone remodeling. An immunohistochemistry protocol for vessel marking in bone was also developed. Ischemia was induced in a mouse model to determine vascular and mechanical property changes in bone in response to hypoxia, and mechanical loading-induced remodeling was analyzed for vascular changes. Both ischemia and mechanical loading increased …

Sex Differences In Mechanisms And Outcome Of Neonatal Hypoxia-Ischemia In Rodent Models: Implications For Sex-Specific Neuroprotection In Clinical Neonatal Practice, Courtney A. Hill, Roslyn Holly Fitch

Open Access Author Fund Awardees' Articles

Clinical findings show that male infants with hypoxic-ischemic injury (HI) fare more poorly than matched females on cognitive outcomes. Rodent models of neonatal hypoxia-ischemia support this difference, with data showing that perinatal brain injury leads to long-term behavioral deficits primarily in male rodents and in female rodents treated with early androgens. Results support the idea that sex-specific gonadal hormones may modulate developmental response to injury and dovetail with overwhelming evidence of developmental androgen effects on typical brain morphology and behavior. However, mechanisms underlying sex differences in response to early brain injury may be more complicated. Specifically, activation of cell death …

Compassion And Coalitions: A Review Of Reshaping The Work Family Debate: Why Men And Class Matter By Joan Williams, Carolyn Shapiro

All Faculty Scholarship

Reshaping the Work-Family Debate: Why Men and Class Matter by Joan Williams is illuminating, intellectually challenging, and insightful. It is not, however, a typical law professor book. Neither academic inquiry nor policy analysis (although it contains elements of both), Reshaping the Work-Family Debate is more of a manifesto. Williams seeks measurable and meaningful change in the family and work lives of Americans, even if that change is imperfect or incomplete, and she sees theoretical or ideological rigidity as one obstacle to such change.

Williams believes that coalition-building is essential to addressing the work family challenges she identifies. Although she has …

A Supplemental Labeling Regime For Organic Products: How The Food, Drugs, And Cosmetic Act Hampers A Market Solution To An Organic Transparency Problem , Ariele Lessing

Journal of Environmental and Sustainability Law

No abstract provided.

Crying Over Spilt Milk: A Closer Look At Required Disclosures And The Organic Milk Industry. International Dairy Foods Association V. Boggs, David A. Martin

Journal of Environmental and Sustainability Law

No abstract provided.

2011 Vol. 60 No. 2, Cleveland-Marshall College Of Law

2010s

No abstract provided.

Acetaminophen: Beyond Pain And Fever-Relieving, Eric R. Blough, Miaozong Wu

MIIR Faculty Research

Acetaminophen, also known as APAP or paracetamol, is one of the most widely used analgesics (pain reliever) and antipyretics (fever reducer). According to the U.S. Food and Drug Administration, currently there are 235 approved prescription and over-the-counter drug products containing acetaminophen as an active ingredient. When used as directed, acetaminophen is very safe and effective; however when taken in excess or ingested with alcohol hepatotoxicity and irreversible liver damage can arise. In addition to well known use pain relief and fever reduction, recent laboratory and pre-clinical studies have demonstrated that acetaminophen may also have beneficial effects on blood glucose levels, …

“Above The American Bottom: The Bluffs And The Sinkhole Plain”, Quinta Scott

The Confluence (2009-2020)

In this photo essay, Quinta Scott examines the natural history of the Mississippi River wetland and the varied landscapes that comprise the American Bottom.

“Contraband Camps In St. Louis: A Contested Path To Freedom”, Jane M. Davis

The Confluence (2009-2020)

During the Civil War, Union officers were sometimes inundated with former slaves, which the Union considered “contraband,” and refused to return them to their owners. Jane Davis examines these contraband camps in St. Louis.

Parallel Implementation Of Maximum Parsimony Search Algorithm On Multicore Cpus, Andrew Darling

Theses

Phylogenetics is the study of the evolutionary relationships among species. It is derived from the ancient greek words, phylon meaning "race", and genetikos, meaning "relative to birth". An important methodology in phylogenetics is a cladistics methodology (parsimony) applied to the study of taxonomic classification. Modern study includes as source data aspects of molecular biology, such as the DNA sequence of homologous (orthologous) genes. The algorithms used attempt to reconstruct evolutionary relationships in the form of phylogenetic trees, based on the available morphological data, behavioral data, and usually DNA sequence data (Fitch W. M., 1971). The topic of this thesis is …

Functional Characterization And Analgesic Effects Of Mixed Cannabinoid Receptor/T-Type Channel Ligands, Haitao You, Vinicius M. Gadotti, Ravil R. Petrov, Gerald W. Zamponi, Philippe Diaz

Biomedical and Pharmaceutical Sciences Faculty Publications

Background: Both T-type calcium channels and cannabinoid receptors modulate signalling in the primary afferent pain pathway. Here, we investigate the analgesics activities of a series of novel cannabinoid receptor ligands with T-type calcium channel blocking activity. Results: Novel compounds were characterized in radioligand binding assays and in vitro functional assays at human and rat CB1 and CB2 receptors. The inhibitory effects of these compounds on transient expressed human T-type calcium channels were examined in tsA-201 cells using standard whole-cell voltage clamp techniques, and their analgesic effects in response to various administration routes (intrathecally, intraplantarly, intraperitoneally) assessed in the formalin model. …

Conversation Currents: Digital Footprints, Julie Coiro, Sara Kajder

College of Education Faculty Publications

No abstract provided.

Collective Action And The Urban Commons, Sheila R. Foster

Notre Dame Law Review

The article presents information the rights of urban residents who share access to several local resources including parks, public spaces and local streets. It includes information on tragedies suffered by common urban resources and also includes information on the current regulations to control common urban resources.

University Housing Newsletter, November 2011, University Of Arkansas, Fayetteville. University Housing

University Housing Newsletter

No abstract provided.

Evolution Of Spur-Length Diversity In Aquilegia Petals Is Achieved Solely Through Cell-Shape Anisotropy, Joshua R. Puzey, Sharon J. Gerbode, Scott A. Hodges, Elena M. Kramer, L. Mahadevan

All HMC Faculty Publications and Research

The role of petal spurs and specialized pollinator interactions has been studied since Darwin. Aquilegia petal spurs exhibit striking size and shape diversity, correlated with specialized pollinators ranging from bees to hawkmoths in a textbook example of adaptive radiation. Despite the evolutionary significance of spur length, remarkably little is known about Aquilegia spur morphogenesis and its evolution. Using experimental measurements, both at tissue and cellular levels, combined with numerical modelling, we have investigated the relative roles of cell divisions and cell shape in determining the morphology of the Aquilegia petal spur. Contrary to decades-old hypotheses implicating a discrete meristematic zone …

Environmental Law Updates

Journal of Environmental and Sustainability Law

No abstract provided.

Ists, November 2011, Iowa Academy Of Science

ISTS Newsletter

In this issue:

--Notes and News

--Thoughts

--Opportunities

Bard Free Press, Vol. 13, No. 3 (November 2011), Bard College

Bard Free Press - All Issues (2000-2018)

No abstract provided.