Digital Commons Network^™

Sequence Analysis Of The Angiotensin Ii Type 1 Receptor (Agtr1) Gene For Mutations Contributing To Pulmonary Hypertension In The Chicken (Gallus Gallus), John Russell Burks

Inquiry: The University of Arkansas Undergraduate Research Journal

Our multidisciplinary group at the University of Arkansas has been investigating the suitability of the chicken as a medical model for pulmonary arterial hypertension (PAH) in humans. There are several forms of PAH in humans arising from elevated pulmonary arterial pressure and pulmonary vascular resistance. Spontaneous cases of PAH are known as idiopathic PAH (IPAH), where the exact physiological causes are not known. IPAH patients that do not respond to standard treatments have a prognosis of only a few years. Currently, there is no acceptable animal model for IPAH. As part of our effort to pursue the chicken as model …

The Competing Visions Of Fairness: The Basic Choice For International Criminal Tribunals, Mirjan Damaska

North Carolina Journal of International Law

No abstract provided.

The Migration Of People: A Model Application Exploring Washington State History, Jamie Nicole Hartman

All Graduate Projects

One of the things that makes Washington State a culturally competent and perceptive place to live is its deep history and appreciation of the migration of its' people. This project is designed to serve as a model and resource for upper elementary school teachers that are seeking to integrate the migration of people into their Washington State History curriculum. A sample inquiry-based curriculum for upper elementary school students "The Migration of People" is offered as a depiction of exceptional classroom practice. Student roles, activities, and assessment methods are portrayed, along with thier connection to core curriculum content and the Washington …

"I Had Never Before ... Heard Of Him At All": William Gilmore Simms, The Elusive William North, And A Lost Simms Novel About American Authorship, Patrick G. Scott

Faculty Publications

Examines a review by the antebellum Southern novelist William Gilmore Simms of a new book by the English writer William North (1825-1854), North's posthumous novel The Slave of the Lamp (1855), discusses possible reasons for Simms's hostility to North such as North's links to the New York Bohemians and his anti-professionalism, and explores what the review reveals about a now-lost Simms novel, with the same title, that gave a different perspective on mid-19th century changes in the conditions and profession of authorship in America.

Stones Of Hope: How African Activists Reclaim Human Rights To Challenge Global Poverty. Edited By Lucie E. White And Jeremy Perelman. Stanford, Ca:Stanford University Press, 2010 [Book Review], Dana Neacsu

Law Faculty Publications

This is a book review of Stones of Hope: How African Activists Reclaim Human Rights to Challenge Global Poverty. Lucie E. White and Jeremy Perelman (eds.). Stanford, CA: Stanford University Press, 2010. PP.280. ISBN 9780804769198. US$70.00 International Journal of Legal Information, 39, pp. 101-103.

Filibustero, Rizal, And The Manilamen Of The Nineteenth Century, Filomeno V. Aguilar Jr

History Department Faculty Publications

This article traces the provenance and the multiple layers of meaning, as well as the contradictions encoded, in the word filibustero from its origins among pirates in the Caribbean in the sixteenth and seventeenth centuries to the American military adventurers in the nineteenth century, whose complex politics intersected with proindependence Cuban exiles. This history illumines the word’s specific meaning as it entered the Philippines before 1872. At the same time, filibustero can be linked to the Manilamen, natives of the Spanish Philippines who worked as international seafarers, who became involved in mercenary activities, especially in Shanghai. This seaborne genealogy contextualizes …

Jose Rizal In Filipino Literature And History, Ambeth R. Ocampo

History Department Faculty Publications

Filipinos in the twenty-first century are separated from their past by the language they speak. While it is true that Jose Rizal, National Hero of the Philippines, wrote a great deal for a nation that cannot read him in the original Spanish, nevertheless his vast and excellent opus guarantees his place in Filipino letters. These include, of course, his two major novels, Noli me tangere, published in 1887, and El filibusterismo, published in 1891, and an annotated edition of Antonio de Morga’s Sucesos de las Islas Filipinas that Rizal completed and published in 1890. Despite the fact that today Rizal’s …

Kentucky Traffic Collision Facts 2011 Report, Kentucky Transportation Center, Kentucky State Police

Kentucky Transportation Center Research Report

KENTUCKY’S TRAFFIC COLLISION FACTS report for 2011 is based on collision reports submitted to the Kentucky State Police Records Branch. As required by Kentucky Revised Statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize data on traffic collisions for such purposes as will improve the traffic safety program in the Commonwealth. Data contained in this report are based solely on the observations …

Evaluation Of Hha And Hha Sepb Mutant Strains Of Escherichia Coli O157:H7 As Bacterins For Reducing E. Coli O157:H7 Shedding In Cattle, Vijay K. Sharma, Evelyn A. Dean-Nystrom, Thomas A. Casey

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Escherichia coli O157:H7 colonizes cattle intestines by using the locus of enterocyte effacement (LEE)- encoded proteins. The induction of systemic immune response against LEE-encoded proteins, therefore, will prove effective in reducing E. coli O157:H7 colonization in cattle. The previous studies have demonstrated that a hha (encodes for a hemolysin expression modulating protein) deletion enhances expression of LEE-encoded proteins and a sepB (encodes an ATPase required for the secretion of LEE-encoded proteins) deletion results in intracellular accumulation of LEE proteins. In this study, we demonstrate the efficacy of the hha and hha sepB deletion mutants as bacterins for …

New Records For The Horse Fly Fauna (Diptera: Tabanidae) Of Jordan With Remarks On Ecology And Zoogeography, Günter Müller, Jerome Hogsette, Edita Revay, Vasiliy Kravchenko, Andrey Leshvanov, Yosef Schlein

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The horse fly fauna (Diptera: Tabanidae) of Jordan is, after Israel, the richest in the Levant, with 24 known species. During the 20-year project “The Ecology and Zoogeography of the Lepidoptera of the Near East,” we regularly collected blood-feeding flies, resulting in 11 additional species of Tabanidae for Jordan. The new records are: Atylotus quadrifarius (Loew, 1874), Chrysops caecutiens (Linnaeus, 1758), Dasyrhamphis nigritus (Fabricius, 1794), Haematopota pallens Loew, 1871, Nemorius irritans (Ricardo, 1901), Philipomyia graeca (Fabricius, 1794), Tabanus cordiger Meigen, 1820, Tabanus taeniola Palisot de Beauvois, 1806, Tabanus quatuornotatus Meigen, 1820, Tabanus separatus Effllatoun, 1930, and Tabanus spectabilis Loew, 1858. …

Vector Competence Of The Stable Fly (Diptera: Muscidae) For West Nile Virus, Michael S. Doyle, Bethany N. Swope, Jerome A. Hogsette, Kristen L. Burkhalter, Harry M. Savage, Roger S. Nasci

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

In 2006-2007, stable flies, Stomoxys calcitrans (L.) (Diptera: Muscidae), were suspected of being enzootic vectors of West Nile virus (family Flaviviridae, genus Flavivirus, WNV) during a die-off of American white pelicans (Pelecanus erythrorhynchos Gmelin) (Pelecanidae) in Montana, USA. WNV-positive stable flies were observed feeding en masse on incapacitated, WNV-positive pelicans, arousing suspicions that the flies could have been involved in WNV transmission among pelicans, and perhaps to livestock and humans. We assessed biological transmission by infecting stable flies intrathoracically with WNV and testing them at 2-d intervals over 20 d. Infectious WNV was detected in fly bodies …

Role Of Notch Signaling In T Cell Polarization, Shilpa Keerthivasan

Dissertations

The differentiation of CD4+ T cells to different effector lineages in response to pathogenic stimuli is the core of the adaptive immune system. One of the effector subsets recently discovered is Thelper 17 (Th17) and it plays a predominant role in autoimmune diseases and inflammatory disorders.

In my thesis, I aimed to study the role of Notch cell surface receptors in Th17 differentiation. Using in vitro Th17 differentiation assays of human naïve CD4+ T cells, I have shown that Notch signaling, particularly Notch1, plays a crucial role in Th17 polarization. By using pharmacological inhibitors and specific knockdown of Notch1, I …

Dietary Wheat Germ Oil Influences Gene Expression In Larvae And Eggs Of The Oriental Fruit Fly, Thomas A. Coudron, Chiou Ling Chang, Cynthia L. Goodman, David Stanley

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Changes in animal nutrition, particularly essential dietary components, alter global gene expression patterns. Our goal is to identify molecular markers that serve as early indicators of the quality of insect culture media. Markers of deficient culture media will increase the efficiency of developing optimal systems for mass rearing beneficial insects and some pest species because decisions on culture media quality can be made without waiting through one or several life cycles. The objective of our current study is to discover molecular markers of essential dietary lipid deficiency in the oriental fruit fly, Bactrocera dorsalis. We reared groups of fruit …

Uncertainty In Modelling Of Faecal Coliform Overland Transport Associated With Manure Application In Maryland, A. K. Guber, Y. A. Pachepsky, A. M. Yakirevich, D. R. Shelton, A. M. Sadeghi, D. C. Goodrich, C. L. Unkrich

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Concerns for microbial safety of surface water facilitate development of predictive models that estimate concentrations and total numbers of pathogen and indicator organisms leaving manure-fertilized fields in overland flow during runoff events. Spatial variability of bacterial concentrations in applied manure introduces high uncertainty in the model predictions. The objective of this work was to evaluate the uncertainty in model predictions of the manure-borne bacteria overland transport caused by limited information on the spatial distribution of bacteria in surface-applied manure. Experiments were carried out at the ARS Beltsville experimental watershed site (OPE3) in Maryland. Dairy bovine manure was applied at a …

Outcrossing And Crossbreeding Recovers Deteriorated Traits In Laboratory Cultured Steinernema Carpocapsae Nematodes, John M. Chaston, Adler R. Dillman, David I. Shapiro-Ilan, Anwar L. Bilgrami, Randy Gaugler, Keith R. Hopper, Byron J. Adams

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The nematode Steinernema carpocapsae infects and kills many pest insects in agro-ecosystems and is commonly used in biocontrol of these pests. Growth of the nematodes prior to distribution for biocontrol commonly results in deterioration of traits that are essential for nematode persistence in field applications. To better understand the mechanisms underlying trait deterioration of the efficacy of natural parasitism in entomopathogenic nematodes, we explored the maintenance of fitness related traits including reproductive capacity, heat tolerance, virulence to insects and ‘tail standing’ (formerly called nictation) among laboratory-cultured lines derived from natural, randomly mating populations of S. carpocapsae. Laboratory cultured nematode …

Forage Soybean Yield And Quality Response To Water Use, David C. Nielsen

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Forages could be used to diversify reduced and no-till dryland cropping systems from the traditional wheat (Triticum aestivum L.)-fallow system in the semiarid central Great Plains. Forages present an attractive alternative to grain and seed crops because of greater water use efficiency and less susceptibility to potentially devastating yield reductions due to severe water stress during critical growth stages. However, farmers need a simple tool to evaluate forage productivity under widely varying precipitation conditions. The objectives of this study were to (1) quantify the relationship between crop water use and dry matter (DM) yield for soybean (Glycine max …

Chapter 30: The Impact Of Extreme Weather Events On Agriculture In The United States, Raymond P. Motha

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The United States has sustained over 90 weather-related disasters in the past 30 years in which overall damages exceeded $1 billion. The total normalized losses for the 90-plus events exceeded $700 billion. Droughts, floods, hurricanes, severe storms, heat waves, freezes, and wildfires pose serious challenges for farmers and the agribusiness community. Socio-economic costs of some of these natural disasters are far-reaching and long-lasting. The enduring changes in climate, water supply, and soil moisture necessitate mitigation measures and adaptation strategies to cope with these changes in order to develop effective long-term risk management plans. The preparedness strategies should include alternatives to …

Alternative Methods And Strategies To Reduce, Refine, And Replace Animal Use For Veterinary Vaccine Post-Licensing Safety Testing: State Of The Science And Future Directions, Jodie Kulpa-Eddy, Geetha Srinivas, Marlies Halder, Karen Brown, Hans Draayer, Jeffrey Galvin, Ivo Claassen, Glen Gifford, Ralph Woodland, Vivian Doelling, Brett Jones, William S. Stokes

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

NICEATM and ICCVAM convened an international workshop to review the state of the science of human and veterinary vaccine potency and safety testing methods and to identify opportunities to advance new and improved methods that can further reduce, refine, and replace animal use. Six topics were addressed in detail by speakers and workshop participants and are reported in a series of six reports. This workshop report, the last in the series, addresses methods and strategies for veterinary vaccine post-licensing safety testing that can reduce, refine, and replace animal use (the 3Rs). It also provides recommendations for priority research and other …

Spatial Ramifications Of Crop Selection: Water Quality And Biomass Energy, M. P. Russelle, D. W. Kelley, A. S. Birr, D. C. Tiffany

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The use of GIS in concert with simple or complex simulation modeling provides an unparalleled way to generate new data and to help a variety of audiences understand spatial patterns of data. From improved understanding, policy incentives can be crafted to reduce adverse environmental impacts of agricultural production at lower costs than would be necessary otherwise. In this chapter, two case studies demonstrate how GIS and modeling can be used to understand how crop selection and soils interact to effect environmental outcomes across an agricultural landscape. We addressed the needs of two distinctly different audiences: (1) a public drinking water …

Efficacy Of Pyriproxyfen For Control Of Stored-Product Psocids (Psocoptera) On Concrete Surfaces, Christos G. Athanassiou, Frank H. Arthur, Nickolas G. Kavallieratos, James E. Throne

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The insect growth regulator pyriproxyfen was evaluated as a surface treatment for control of three stored-product psocid pests Liposcelis bostrychophila Badonnel, Liposcelis decolor (Pearman), and Liposcelis paeta Pearman (Psocoptera: Liposcelididae). Nymphs were exposed for 35 d on a concrete surface treated with 2.3 mg of active ingredient/m² pyriproxyfen. Exposure to pyriproxyfen significantly reduced the numbers of both adults and nymphs in comparison with untreated controls. In adults, the greatest reduction (>90%) was for L. decolor and L. bostrychophila, whereas for L. paeta it was 49%. Few adults of any species were found in the pyriproxyfen treatments. The …

Efficacy Of Spinosad And Methoprene, Applied Alone Or In Combination, Against Six Stored-Product Insect Species, Christos G. Athanassiou, Frank H. Arthur, Nickolas G. Kavallieratos, James E. Throne

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Efficacy of the insecticides spinosad and methoprene, applied alone or in combination to wheat, was evaluated against six stored-product insect species, Rhyzopertha dominica, Sitophilus oryzae, S. granarius, Cryptolestes ferrugineus, Oryzaephilus surinamensis, and Liposcelis bostrychophila. The concentrations of the insecticides were 0.1 and 0.5 ppm for spinosad and 1 and 5 ppm for methoprene. Parental mortality of R. dominica was 100% on wheat treated with either rate of spinosad, with no progeny production in any combination treatment. Parental mortality of S. oryzae did not exceed 62%, and progeny production was not reduced by any insecticide …

Efficacy Of Layer Treatment With Methoprene For Control Of Rhyzopertha Dominica (Coleoptera: Bostrychidae) On Wheat, Rice Andmaize, Christos G. Athanassiou, Frank H. Arthur, James E. Throne

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

BACKGROUND: Insect growth regulators are promising alternatives to traditional pesticides in stored grain. The efficacy of the juvenile hormone analogue methoprene was evaluated as a layer treatment in a laboratory experiment for control of Rhyzopertha dominica (F.) (Coleoptera: Bostrychidae) in wheat, rice and maize.

RESULTS: Adults of R. dominica were placed in vials containing 33, 26 and 29 g (to a depth of 6.5 cm) of wheat, rice and maize, respectively, that was entirely or partially treated with 1, 5 or 10mg kg⁻¹ methoprene. In wheat and rice, the layer treatments were not as effective as the whole-grain treatment, …

Small, Slow, And Local: Essays On Building A More Sustainable And Local Food System, Mary Jane Angelo, Amelia Timbers, Matthew J. Walker, Joshua B. Donabedian, Devon Van Noble, Erik Phillips-Nania, Emily Parish, Jennifer L. Perez

UF Law Faculty Publications

A collection of essays that have strong arguments in favor of shifting from our existing centralized industrial agricultural system to a more localized system. This shift will reduce reliance on fossils fuels, which are used to make pesticide and fertilizer inputs and to transport foods long distances, thereby reducing contributions to climate change and decreasing environmental impacts. The shift will also provide social and economic benefits to local communities, improved health and a more sustainable, secure, and resilient food supply. To achieve such a shift, however, it will be necessary to overcome existing legal, economic, and social barriers and to …

Conservation Easements At The Climate Change Crossroads, Jessica Owley

Articles

No abstract provided.

Preliminary Efficacy Of A Computer-Delivered Hiv Prevention Intervention For African American Teenage Females, Charles H. Klein, Josefina J. Card

Anthropology Faculty Publications and Presentations

This study translated SiHLE (Sisters Informing, Healing, Living, and Empowering), a 12-hour Centers for Disease Control and Prevention evidence based group-level intervention for African American females 14-18 years of age, into a 2-hour computer-delivered individual-level intervention. A randomized controlled trial (n = 178) was conducted to examine the efficacy of the new Multimedia SiHLE intervention. Average condom-protected sex acts (proportion of vaginal sex acts with condoms, last 90 days) for sexually active participants receiving Multimedia SiHLE rose from M = 51% at baseline to M = 71% at 3-month follow-up (t = 2.06, p = .05); no statistically significant difference …

Nutritional Plane And Selenium Supply During Gestation Affect Yield And Nutrient Composition Of Colostrum And Milk In Primiparous Ewes, A. M. Meyer, J. J. Reed, T. L. Neville, J. F. Thorson, K. R. Maddock-Carlin, J. B. Taylor, L. P. Reynolds, D. A. Redmer, J. S. Luther, C. J. Hammer, K. A. Vonnahme, J. S. Caton

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The objectives were to investigate effects of nutritional plane and Se supply during gestation on yield and nutrient composition of colostrum and milk in first parity ewes. Rambouillet ewe lambs (n = 84, age = 240 ± 17 d, BW = 52.1 ± 6.2 kg) were allocated to 6 treatments in a 2 × 3 factorial array. Factors included Se [adequate Se (ASe, 11.5 µg/ kg of BW) or high Se (HSe, 77.0 µg/kg of BW)] initiated at breeding, and nutritional plane [60 (RES), 100 (CON), or 140% (HIH) of requirements] initiated at d 40 of gestation. Ewes were fed …

Putting The Whole Grain Puzzle Together: Health Benefits Associated With Whole Grains—Summary Of American Society For Nutrition 2010 Satellite Symposium, Satya S. Jonnalagadda, Lisa Harnack, Rui Hai Liu, Nicola Mckeown, Chris Seal, Simin Liu, George C. Fahey

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The symposium “Putting the Whole Grain Puzzle Together: Health Benefits Associated with Whole Grains” sponsored by the ASN brought together researchers to review the evidence regarding the health benefits associated with whole grains. Current scientific evidence indicates that whole grains play an important role in lowering the risk of chronic diseases, such as coronary heart disease, diabetes, and cancer, and also contribute to body weight management and gastrointestinal health. The essential macro- and micronutrients, along with the phytonutrients present in whole grains, synergistically contribute to their beneficial effects. Current evidence lends credence to the recommendations to incorporate whole grain foods …

What Kind Of Environment Do We Owe Future Generations?, Neil H. Buchanan

UF Law Faculty Publications

Despite widely held beliefs that current generations bear heavy obligations to look out for the welfare of future generations, the philosophical case in support of such intergenerational obligations is surprisingly tentative. Moreover, quantifying any such obligations is subject to even greater uncertainty. Even so, current generations bring future generations into existence in the knowledge that doing so will put a claim on resources that could have been used to reduce suffering among people who are already alive. The choice to allow living people to suffer and die, and instead to bring forth more people in the future, thus implies a …

The Admissibility Of Electronic Evidence Under The Federal Rules Of Evidence, Jonathan D. Frieden, Leigh M. Murray

Richmond Journal of Law & Technology

Following the December 2006 amendments to the Federal Rules of Civil Procedure, much has been written about the discovery of electronically-stored information.

Federal Rule Of Evidence 502: Has It Lived Up To Its Potential?, Paul W. Grimm, Lisa Yurwit Bergstrom, Matthew P. Kraeuter

Richmond Journal of Law & Technology

Nothing causes litigators greater anxiety than the possibility of doing, or failing to do, something during a civil case that waives attorney– client privilege or work-product protection. Attend any seminar, webcast, podcast, or other continuing legal education course dealing with the discovery of electronically stored information (“ESI”) and you are sure to hear about this concern and how to mitigate it.