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Map Kinases Phosphorylate Spf45 And Regulate Its Alternative Splicing Function: Insights Onto Phosphorylation-Dependent And -Independent Effects In Ovarian Cancer Cells, Adnan Al-Ayoubi

MUSC Theses and Dissertations

Alternative pre-mRNA splicing increases proteome diversity and is important in the behavior of cells in health and disease. The processes that regulate alternative premRNA splicing are diverse and include regulation of splicing factors by phosphorylation. Here we report that the pre-mRNA alternative splicing factor SPF45 is a novel substrate of ERK, JNK and p38 MAP kinases in ovarian cancer cells. Using mutational analysis and phospho-specific antibodies, we demonstrate that MAP kinases phosphorylate SPF45 on Thr71 and Ser222 and that phosphorylation in cells is induced by a number of extracellular stimuli including PMA, EGF, serum, H20 2 and UV. Exon 6 …

Seven-Sky V. Holder - Amicus Brief Of Constitutional Accountability Center, Constitutional Accountability Center

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Thomas More Law Center V. Obama - Amicus Brief Of Oregon Et Al., State Of Oregon

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Coons V. Geithner - U.S. Reply In Support Of Motion For Summary Judgement, United States Department Of Health And Human Services

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Coons V. Geithner - Amended Complaint, Nick Coons

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Bryant V. Holder - Amended Complaint (Third Amended Petition), Phil Bryant

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Bryant V. Holder - Second Amended Petition, Phil Bryant

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Goudy-Bachman V. Hhs - District Court Opinion Grating Summary Judgement, United States District Court For The Middle District Of Pennsylvania

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Goudy-Bachman V. Hhs - Plaintiffs' Motion For Summary Judgement, Barbara Goudy-Bachman

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Goudy-Bachman V. Hhs - U.S. Response To Supplemental Brief, Barbara Goudy-Bachman

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Goudy-Bachman V. Hhs - Plaintiffs' Supplemental Brief On Florida V. Hhs, Barbara Goudy-Bachman

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Virginia V. Sebelius - Virginia Motion For Summary Judgement, Commonwealth Of Virginia

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Virginia V. Sebelius - Amicus Of American Civil Rights Union, American Civil Rights Union

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Virginia V. Sebelius - Amicus Brief Of Washington Legal Foundation, Washington Legal Foundation

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Florida V. Hhs - Amicus Brief Of State Legislators, Elizabeth B. Wydra

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Florida V. Hhs - States Motion For Summary Judgment, State Of Florida

Patient Protection and Affordable Care Act Litigation

No abstract provided.

Characterization Of Viral And Host Proteins And Rna Elements In Tombusvirus Replication, Kunj Bihari Pathak

Theses and Dissertations--Plant Pathology

Two thirds of plant viruses are positive-strand RNA viruses including the family Tombusviridae. One of the best-studied members of this family is Tomato bushy stunt virus (TBSV). Like many other viruses, TBSV has much fewer genes when compared to its hosts’ genome. Nevertheless, TBSV utilizes its genome very judiciously. To compensate for a lack of many proteins of its own, it codes for multi-functional replication protein p33 and also co-opts host factors to facilitate its replication.

By using recombinant replication proteins p33 and p92 containing single amino acid changes in protein-protein interaction domains (S1 and S2), I demonstrated that the …

The Thirteenth Amendment, Interest Convergence, And The Badges And Incidents Of Slavery, William M. Carter Jr.

Maryland Law Review

No abstract provided.

The Gospel Of Matthew: The Temple Cleansing In 21:12-17, Kasey Devine

School of Theology and Seminary Graduate Papers/Theses

In this paper, the cleansing of theTempleis described as a story of both judgment and challenge. Matthew illustrates Jesus to his post-Temple community as the Jewish continuation of Moses and the Law, the fiery prophet critiquing the economic system set up by the chief priests and scribes, and God himself who brings judgment to his people. The story challenged Matthew’s community and challenges the modern reader to end oppression, attend to the marginalized, and accept Jesus as the newTemple– the continuation of Judaism. This story can be seen in terms of liturgy and Baptism in the Church, and confronts our …

Academic And Research Responsibilities Of Tenured Faculty In Arts And Sciences Senate Constituencies At Stony Brook University., Stony Brook University. Arts And Sciences Senate. Faculty Rights And Responsibilities Policy Committee.

Arts and Sciences Committee on Faculty Rights and Responsibilities

No abstract provided.

Use Of Dry-Rolled Corn, Dry Or Wet Distillers Grains Plus Solubles As An Energy Source In High Forage Diets For Growing Cattle, Nerissa A. Ahern, Brandon L. Nuttelman, Crystal D. Buckner Buckner, Terry Klopfenstein, Galen Erickson

Nebraska Beef Cattle Reports

One hundred twenty crossbred steers were used to determine the energy value of distillers grains relative to corn in high-forage diets. Diets included dry distillers grains plus solubles (DDGS), wet distillers grains plus solubles (WDGS) or dry-rolled corn (DRC), with sorghum silage, grass hay, and supplement. Each block of steers, by design, had similar dry matter intake (DMI) and average daily gain (ADG) across treatments. In this study, WDGS and DDGS contained 120% and 114%, respectively, the energy of DRC when fed in forage-based diets.

Impact Of Distillers Grains Moisture And Inclusion Level On Greenhouse Gas Emissions In The Corn-Ethanol-Livestock Life Cycle, Virgil R. Bremer, Adam Liska, Galen E. Erickson Erickson, Kenneth Cassman, Kathryn J. Hanford, Terry Klopfenstein

Nebraska Beef Cattle Reports

Updated meta-analysis of cattle performance equations were incorporated into the Biofuel Energy Systems Simulator (BESS) to more accurately evaluate the greenhouse gas (GHG) benefit of corn ethanol relative to gasoline. Partial drying or complete drying of wet distillers grains (DGS) reduces the feeding value of DGS for cattle and increases ethanol GHG emissions. Feeding wet DGS provides the optimum GHG benefit relative to gasoline, with associated ethanol emissions being 40% of gasoline. Ethanol production with dried DGS results in about 60% of the GHG emissions of gasoline when dry DGS is fed to feedlot cattle, dairy cows, and finishing swine.

2011 Nebraska Beef Cattle Report [Complete]

Nebraska Beef Cattle Reports

mp94.indd

Cow/Calf

Winter Grazing System and Supplementation of Beef Cows During Late Gestation Influence Heifer Progeny

Influencing Steer Performance Through Maternal Nutrition

Integration of DNA Marker Information into Breeding Value Predictions

Granulosa Cell Gene Expression is Altered in Follicles from Cows with Differing Reproductive Longevity

Growing

Performance of Growing Cattle Fed Corn Silage or Grazing Corn Residue from Second Generation Insect-protected (MON 89034), Parental, or Reference Corn Hybrids

Nutrient Composition of Spoiled Wet Byproducts Mixed and Stored with Straw

Use of Dry Rolled Corn, Dry or Wet distillers Grains Plus Solubles as an Energy Source in High Forage Diets for …

Economics For Feeding Distillers Grains To Finishing Cattle, Crystal D. Buckner, Terry Klopfenstein, Galen Erickson Erickson, Virgil R. Bremer, Darrell Mark

Nebraska Beef Cattle Reports

Cattle CODE, an economic budget model for predicting feeding returns for distillers grains, was updated and four new economic scenarios were evaluated. Feeding WDGS resulted in larger economic returns compared to MDGS and DDGS when the hauling distance from the ethanol plant to the feedlot was less than 60 miles and the dietary inclusion was up to 40% DM. However, these economic returns were dependent on the price paid for the products. If MDGS and DDGS were priced based on their drying costs, then economic returns decreased compared to WDGS.

Granulosa Cell Gene Expression Is Altered In Follicles From Cows With Differing Reproductive Longevity, Andrea Cupp, Jennifer R. Wood, Renee Mcfee Fee, Racheal G. Slattery, Kevin A. Beavers, William E. Pohlmeier, Kevin M. Sargent, Ningxia Lu, Jacqueline Smith, Jill G. Kerl, Vanessa M. Brauer, Adam F. Summers, Stetson P. Weber, Robert A. Cushman

Nebraska Beef Cattle Reports

Heifers and cows that were culled from the herd due to failure to become pregnant were categorized into groups with low (< 2 year), moderate (>2 and < 6 year) or high (≥ 6 year) fertility. Antral follicle counts were numerically lower in the low group and increased in the moderate- and high-fertility group. Granulosa cells from dominant follicles in moderate- and high-fertility cows had a greater ratio of Vascular Endothelial Growth Factor 164 (VEGF164) to VEGF164B compared to the low-fertility cows. Furthermore, there was more CARTPT in granulosa cells from subordinate follicles in moderate- and high-fertility cows than low. Gene expression is altered in granulosa cells from cows differing in fertility, suggesting these are candidate genes that may be used as markers to assist in determining reproductive longevity in beef cows.

Feeding Strategies Of Optaflexx On Growth Performance And Carcass Characteristics Of Feedlot Steers, Marco G. Dib, William A. Griffin, Joshua R. Benton Benton, Galen Erickson, Terry Klopfenstein, Justin J. Sindt, W. Travis Choat

Nebraska Beef Cattle Reports

Live BW and carcass traits of steer calves were evaluated after feeding Optaflexx (200mg/day) for 35 days on an intermittent basis or continuously. The negative control consisted of 63 days on the same diet without Optaflexx, whereas the positive control consisted of Optaflexx supplemented daily during the last 35 days prior to harvest. The four-day intermittent treatment consisted of feeding Optaflexx for seven days, followed by four days of no Optaflexx, while the seven-day intermittent treatment consisted of seven days on Optaflexx, followed by seven days off. In both the four-day and seven-day intermittent treatments, cattle received Optaflexx for a …

Effects Of Feeding A Combination Of Modified Distillers Grains Plus Solubles And Wet Corn Gluten Feed To Adapt Cattle To Finishing Diets, Marco G. Dib, Kelsey Rolfe, Jhones O. Sarturi Sarturi, Galen Erickson, Terry Klopfenstein, Ron Lindquist

Nebraska Beef Cattle Reports

Two 39-day metabolism trials were conducted using a combination of modified distillers grains and wet corn gluten feed (Synergy, ADM) to adapt beef cattle to finishing diets (SYNERGY). During adaptation, DMI expressed as % of BW tended to be greater for steers on traditional grain adaptation with forage (CON) compared to SYNERGY during the first period (steps 1), but was not different in subsequent adaptation diets (steps 2, 3, and 4). Average ruminal pH was lower for SYNERGY on steps 1 and 2 compared to CON in Experiment 1 with no difference observed in Experiment 2. No difference in ruminal …

Winter Grazing System And Supplementation Of Beef Cows During Late Gestation Influence Heifer Progeny, Richard N. Funston, Jeremy L. Martin, Adam F. Summers, Don Adams, Jacqueline Musgrave, T. L. Meyer, Daniel M. Larson

Nebraska Beef Cattle Reports

Effects of cow winter grazing system and supplementation on heifer progeny were evaluated. Cows grazed range (WR) or corn residue (CR) with (PS) or without (NS) supplement. Both PS and CR increased weaning weight. Heifersfrom WR-NS dams weighed less at breeding and pregnancy diagnosis than WR-PS. Heifers from PS dams were younger at puberty, and pregnancy rate tended to be greater. Heifers from CR-PS dams gained the least and were least efficient. First-calf production and rebreeding were similar. There appear to be fetal programming effects of dam winter grazing system and supplementation on heifer progeny.

Performance And Carcass Characteristics Of Finishing Steers Fed Low-Fat And Normal-Fat Wet Distillers Grains, Jennifer A. Gigax, Brandon L. Nuttelman, William A. Griffin Griffin, Galen Erickson, Terry Klopfenstein

Nebraska Beef Cattle Reports

Wet distillers grains plus solubles (WDGS) varying in fat content (6.7 vs. 12.9 %) were fed at 35% of the diet DM to compare fat level from WDGS on cattle performance and carcass characteristics. Final BW, hot carcass weight, and ADG were increased for steers fed 12.9% fat WDGS compared to steers fed corn or 6.7% fat WDGS. Steers fed 6.7% fat WDGS or corn control diets had identical DMI, ADG, and F:G.

Effect Of Stocking Rate On Animal Performance And Diet Quality While Grazing Cornstalks, Jennifer A. Gigax, Crystal D. Buckner, L. Aaron Stalker Stalker, Terry Klopfenstein, Simon J. Van Donk

Nebraska Beef Cattle Reports

Four treatments were used to evaluate levels of corn residue removal on nutrient quality and cattle performance over time. Treatments included no removal of residue, stocking rates of one or two animal unit months/acre (AUM/acre), or baling. Residue samples were taken before and after grazing from all treatment paddocks to determine residue amounts, and were analyzed for OM, CP, NDF, and in vitro organic matter digestibility (IVOMD). Cattle weights and BCS scores were recorded prior to and at the conclusion of the trial. Cattle consumed husk and leaf material first, followed by cobs at a lesser rate. Husk and leaf …