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Himmelfarb Headlines - September/October 2010, George Washington University, Himmelfarb Health Sciences Library

Himmelfarb Headlines (2009 - present)

News and information about Himmelfarb Health Sciences Library of interest to users. Includes articles on mobile initiatives, DynaMed, and profiles of Alex Stagnaro-Green, MD, and Tom Harrod.

Time Series Of Bio-Optical Properties In A Subtropical Gyre: Implications For The Evaluation Of Interannual Trends Of Biogeochemical Properties, Zhongping Lee, Shaoling Shang, Chuanmin Hu, Marlon Lewis, Robert Arnone, Yonghong Li, Bertrand Lubac

Marine Science Faculty Publications

With a validated Quasi‐Analytical Algorithm, an 11 year (1998–2008) monthly time series of the primary optical properties of waters in the center of the South Pacific gyre was developed from Sea‐viewing Wide Field‐of‐view Sensor (SeaWiFS) and Moderate Resolution Imaging Spectroradiometer (MODIS). Also derived are chlorophyll a (Chl a) concentrations with the operational empirical algorithms for SeaWiFS and MODIS. The optical properties include the absorption coefficient (at 443 nm) of phytoplankton (a_ph) and that of the combination of detritus and gelbstoff (a_dg). From these time series, we further derived their annual background (summer low) …

The Uneven Distribution Of Social Suffering: Documenting The Social Health Consequences Of Neo-Liberal Social Policy On Marginalized Youth, Michelle Fine, Brett G. Stoudt, Maddy Fox, Maybelline Santos

Publications and Research

In 2009, British epidemiologists Richard Wilkinson and Kate Pickett published "The Spirit Level: Why Greater Equality Makes Societies Strong", in which they argue that severely unequal societies produce high rates of ‘social pain”: adverse outcomes including school drop out, teen pregnancy, mental health problems, lack of social trust, high mortality rates, violence and crime, low social participation. Their volume challenges the belief that the extent of poverty in a community predicts negative outcomes. They assert instead that the size of the inequality gap defines the material and psychological contours of the chasm between the wealthiest and the most impoverished, enabling …

Multiple Trophic Levels Fueled By Recirculation In The Columbia River Plume, Raphael M. Kudela, Alexander R. Horner-Devine, Neil S. Banas, Barbara M. Hickey, Tawnya D. Peterson, Ryan M. Mccabe, Evelyn J. Lessard, Elizabeth R. Frame, Kenneth W. Bruland, David A. Jay, Jay O. Peterson, William T. Peterson, P. Michael Kosro, Sherry L. Palacios, Maeve C. Lohan, Edward P. Dever

Civil and Environmental Engineering Faculty Publications and Presentations

Large rivers represent gateways for the transport of terrigenous and anthropogenic material to the coastal ocean. Here we document a ?700 km2 recirculation or bulge associated with the Columbia River plume that retains recently discharged river water sufficiently to create a regional bioreactor. Fueled by a fluvial nitrate source, this feature stimulated growth across three trophic levels and may buffer this gateway system during periods of increased warming and stratification that lead to decreased ocean productivity, potentially enhancing production at multiple trophic levels and enriching surfacewaters far from the river mouth.

2010 Willow Flycatcher Surveys At Three Albuquerque Sites: Brown Burn, Montano Southwest And Rio Bravo Northeast, Hawks Aloft, Inc.

Single Species Reports (Hawks Aloft)

No abstract provided.

Web-Based Weapons Of Mass Destruction Training For Transit Police, Lori A. Magda, Allison N. Canton, Robyn R.M. Gershon

Journal of Public Transportation

In response to increased terrorist attacks on mass transit systems worldwide, emergency planning and security efforts have intensified. One of the most important planning elements is the provision of training for first-response personnel. Yet few terrorism-related training programs specific to the mass transit sector are available. To address this unmet need, a web-based weapons of mass destruction (WMD) simulation training program, specifically designed for transit police, was recently developed, implemented, and evaluated. Results indicate that this program was effective in improving transit police officers’ ability to recognize and respond to WMD simulations.

Designing And Implementing A Longitudinal Study Of Children With Neurological, Genetic, Or Metabolic Conditions: Charting The Territory, Harold Siden, Rose Steele, Rollin Brant, Susan Cadell, Betty Davies, Lynn Straatman, Kimberley Widger, Gail S. Andrews

Lyle S. Hallman Social Work Faculty Publications

Background: Children with progressive metabolic, neurological, or chromosomal conditions and their families anticipate an unknown lifespan, endure unstable and often painful symptoms, and cope with erratic emotional and spiritual crises as the condition progresses along an uncertain trajectory towards death. Much is known about the genetics and pathophysiology of these diseases, but very little has been documented about the trajectory of symptoms for children with these conditions or the associated experience of their families. A longitudinal study design will help to close this gap in knowledge.

Methods/Design: Charting the Territory is a longitudinal descriptive, correlational study currently underway with children …

Least-Cost Control Of Agricultural Nutrient Contributions To The Gulf Of Mexico Hypoxic Zone, Sergey Rabotyagov, Todd Campbell, Manoj Jha, Philip W Gassman, Jeffrey Arnold, Lyubov Kurkalova, Silvia Secchi, Hongli Feng, Catherine L Kling

Articles

In 2008, the hypoxic zone in the Gulf of Mexico, measuring 20 720 km2, was one of the two largest reported since measurement of the zone began in 1985. The extent of the hypoxic zone is related to nitrogen and phosphorous loadings originating on agricultural fields in the upper Midwest. This study combines the tools of evolutionary computation with a water quality model and cost data to develop a trade-off frontier for the Upper Mississippi River Basin specifying the least cost of achieving nutrient reductions and the location of the agricultural conservation practices needed. The frontier allows policymakers and stakeholders …

September 1, 2010 Faculty Senate Minutes, University Of South Carolina

Faculty Senate

No abstract provided.

The Chlorella Variabilis Nc64a Genome Reveals Adaptation To Photosymbiosis, Coevolution With Viruses, And Cryptic Sex, Guillaume Blanc, Garry Duncan, Irina Agarkova, Mark Borodovsky, James Gurnon, Alan Kuo, Erika Lindquist, Susan Lucas, Jasmyn Pangilinan, Juergen Polle, Asaf Salamov, Astrid Terry, Takashi Yamada, David D. Dunigan, Igor V. Grigoriev, Jean-Michel Claverie, James L. Van Etten

Department of Plant Pathology: Faculty Publications

Chlorella variabilis NC64A, a unicellular photosynthetic green alga (Trebouxiophyceae), is an intracellular photobiont of Paramecium bursaria and a model system for studying virus/algal interactions. We sequenced its 46-Mb nuclear genome, revealing an expansion of protein families that could have participated in adaptation to symbiosis. NC64A exhibits variations in GC content across its genome that correlate with global expression level, average intron size, and codon usage bias. Although Chlorella species have been assumed to be asexual and nonmotile, the NC64A genome encodes all the known meiosis-specific proteins and a subset of proteins found in flagella. We hypothesize that Chlorella might have …

Prospectus, September 1, 2010, Janelle O'Dea, Chuck Shepherd, Patrick Wood, Julio Mcneal, Kelley Heaney, Morgan Bernier

Prospectus 2010

MAYBE MONEY DOES GROW ON TREES: A GUIDE TO YOUR FINANCIAL AID PAPERWORK PROCESS; Colleges say new health law may imperil student policies; Chuck Shepherd's News of the Weird; Passion Pit Finally Makes it to the C-U, Finally!; Campus wants greater attire awareness; Older adults' use social networks growing fast, study finds; How to save public television: The PBS Channel; Pricy conditions for new book editions; Bicycle safety a growing concern in Illinois; Dogs and other pets welcome at Florida dorm; Prospectus Pick: Murder By Death; Understanding Islam

Three-Dimensional Structure Of The Weakly Associated Protein Homodimer Ser13 Using Rdcs And Paramagnetic Surface Mapping, Hsiau Wei Lee, Greg Wylie, Sonal Bansal, Xu Wang, Adam W. Barb, Megan A. Macnaughtan, Asli Ertekin, Gaetano T. Montelione, James H. Prestegard

Faculty Publications

The traditional NMR-based method for determining oligomeric protein structure usually involves distinguishing and assigning intra- and intersubunit NOEs. This task becomes challenging when determining symmetric homo-dimer structures because NOE cross-peaks from a given pair of protons occur at the same position whether intra- or intersubunit in origin. While there are isotope-filtering strategies for distinguishing intra from intermolecular NOE interactions in these cases, they are laborious and often prove ineffectual in cases of weak dimers, where observation of intermolecular NOEs is rare. Here, we present an efficient procedure for weak dimer structure determination based on residual dipolar couplings (RDCs), chemical shift …

A Global Census Of Fission Yeast Deubiquitinating Enzyme Localization And Interaction Networks Reveals Distinct Compartmentalization Profiles And Overlapping Functions In Endocytosis And Polarity, Ilektra Kouranti, Janel R. Mclean, Anna Feoktistova, Ping Liang, Alyssa E. Johnson, Rachel H. Roberts-Galbraith, Kathleen L. Gould

Faculty Publications

Ubiquitination and deubiquitination are reciprocal processes that tune protein stability, function, and/or localization. The removal of ubiquitin and remodeling of ubiquitin chains is catalyzed by deubiquitinating enzymes (DUBs), which are cysteine proteases or metalloproteases. Although ubiquitination has been extensively studied for decades, the complexity of cellular roles for deubiquitinating enzymes has only recently been explored, and there are still several gaps in our understanding of when, where, and how these enzymes function to modulate the fate of polypeptides. To address these questions we performed a systematic analysis of the 20 Schizosaccharomyces pombe DUBs using confocal microscopy, proteomics, and enzymatic activity …

The Herpes Simplex Virus Type 1 Ul20 Protein And The Amino Terminus Of Glycoprotein K (Gk) Physically Interact With Gb, Vladimir N. Chouljenko, Arun V. Iyer, Sona Chowdhury, Joohyun Kim, Konstantin G. Kousoulas

Faculty Publications

Herpes simplex virus type 1 (HSV-1) glycoprotein K (gK) and the UL20 protein (UL20p) are strictly required for virus-induced cell fusion, and mutations within either the gK or UL20 gene cause extensive cell fusion (syncytium formation). We have shown that gK forms a functional protein complex with UL20p, which is required for all gK and UL20p-associated functions in the HSV-1 life cycle. Recently, we showed that the amino-terminal 82 amino acids (aa) of gK (gKa) were required for the expression of the syncytial phenotype of the mutant virus gBΔ28 lacking the carboxyl-terminal 28 amino acids of gB (V. N. Chouljenko, …

Swosu Fact Book Fall 2010, Denisa Engelman

Fact Books

I am proud to introduce the 19th annual Southwestern Oklahoma State University Fact Book. The Fact Book provides a ready source of information to answer frequently asked questions about the University and its operations. Unless otherwise noted, the information in this Fact Book came from computer-generated reports that are printed following the tenth class day of each fall semester. Because of student fluctuations during the semester, numbers will not match other published enrollment numbers that may be based on enrollment at the end of a semester.

Technology And Communications Coursework: Facilitating The Progression Of Students With Learning Disabilities Through High School Science And Math Coursework, Dara Shifrer, Rebecca Callahan

Sociology Faculty Publications and Presentations

Students identified with learning disabilities experience markedly lower levels of science and mathematics achievement than students who are not identified with a learning disability. Seemingly compounding their disadvantage, students with learning disabilities also complete more credits in non-core coursework—traditionally considered nonacademic coursework—than students who are not identified with a learning disability. The Education Longitudinal Study of 2002, a large national dataset with both regular and special education high school students, is utilized to determine whether credit accumulation in certain types of non-core coursework, such as technology and communications courses, is associated with improved science and math course taking outcomes for …

Expression Of A Low Co2-Inducible Protein, Lci1, Increases Inorganic Carbon Uptake In The Green Alga Chlamydomonas Reinhardtii, Norikazu Ohnishi, Hideya Fukuzawa, Bratati Mukherjee, Tomoki Tsujikawa, Mari Yanase, Hirobumi Nakano, James V. Moroney

Faculty Publications

Aquatic photosynthetic organisms can modulate their photosynthesis to acclimate to CO2-limiting stress by inducing a carbon-concentrating mechanism (CCM) that includes carbonic anhydrases and inorganic carbon (Ci) transporters. However, to date, Ci-specific transporters have not been well characterized in eukaryotic algae. Previously, a Chlamydomonas reinhardtii mutant (lcr1) was identified that was missing a Myb transcription factor. This mutant had reduced light-dependent CO2 gas exchange (LCE) activity when grown under CO2-limiting conditions and did not induce the CAH1 gene encoding a periplasmic carbonic anhydrase, as well as two as yet uncharacterized genes, LCI1 and LCI6. In this study, LCI1 was placed under …

Stabilization Of A Chemostat Model With Haldane Growth Functions And A Delay In The Measurements, Frédéric Mazenc, Michael Malisoff

Faculty Publications

The stabilization of equilibria in chemostats with measurement delays is a complex and challenging problem, and is of significant ongoing interest in bioengineering and population dynamics. In this paper, we solve an output feedback stabilization problem for chemostat models having two species, one limiting substrate, and either Haldane or Monod growth functions. Our feedback stabilizers depend on a given linear combination of the species concentrations, which are both measured with a constant time delay. The values of the delays are unknown. Instead, one only knows an upper bound on the delays, and we allow the upper bound to be arbitrarily …

Delineation Of Differential Temporal Relations Between Specific Eating And Anxiety Disorders, Julia D. Buckner, Jose Silgado, Peter M. Lewinsohn

Faculty Publications

This study examined the temporal sequencing of eating and anxiety disorders to delineate which anxiety disorders increase eating disorder risk and whether individuals with eating disorders are at greater risk for particular anxiety disorders. The sample was drawn from the Oregon Adolescent Depression Project. Temporal relations between specific eating and anxiety disorders were examined after controlling for relevant variables (e.g., mood disorders, other anxiety disorders) over 14. years. After excluding those with anorexia nervosa (AN) in adolescence (T1), OCD was the only T1 anxiety disorder to predict AN by age 30 (T4). No T1 anxiety disorder was associated with T4 …

Delivering The Goods: Creating Materials To Aid Regenerative Medicine, Julie O'Connor

New Science

Imagine a time in the future when human lifespan is extended because “broken parts” are simply replaced by regenerated ones. Lives may be lengthened by several decades because of new technologies that create cells, tissues and organs for patients who may need them. Research at Wayne State is putting us closer to the day when this will happen. The development of biomaterial scaffolds plays a central role in regenerative medicine by providing the chemical, biological and mechanical cues necessary for tissue formation or regeneration.

Fast Track For Stem Cells: Detroit's Hub For Research And Commercialization, Amy Oprean

New Science

Since the U.S. ban on stem cell research was lifted on March 9, 2009, many pockets of promising research have sprung up across the country as scientists scramble to recharge their efforts in a field that holds tremendous potential. Through a multitude of funding opportunities and exceptional expertise, Michigan’s University Research Corridor – the alliance between Wayne State University, University of Michigan and Michigan State University – has positioned the state to be a major hub for stem cell advancement. Detroit holds particular promise, housing both Wayne State University and Stem Cell Commercialization Center located at TechTown, the university’s research …

New Science Volume 18, Division Of Research

New Science

Full issue to Volume 18 of New Science

How To Be Successful In Exclusive Breastfeeding For Four To Six Months:Experiences Of Chinese Mothers In Ireland, Qianling Zhou

Other resources

No abstract provided.

College Suicide: A Law And Policy Perspective, Gary Pavela

Washington and Lee Journal of Civil Rights and Social Justice

No abstract provided.

A Role For The Histone Deacetylase Hdac4 In The Life-Cycle Of Hiv-1-Based Vectors., Johanna A Smith, Jennifer Yeung, Gary D Kao, René Daniel

Department of Medicine Faculty Papers

HIV-1 integration is mediated by the HIV-1 integrase protein, which joins 3'-ends of viral DNA to host cell DNA. To complete the integration process, HIV-1 DNA has to be joined to host cell DNA also at the 5'-ends. This process is called post-integration repair (PIR). Integration and PIR involve a number of cellular co-factors. These proteins exhibit different degrees of involvement in integration and/or PIR. Some are required for efficient integration or PIR. On the other hand, some reduce the efficiency of integration. Finally, some are involved in integration site selection. We have studied the role of the histone deacetylase …

Self-Imaging Of Molecules From Diffraction Spectra By Laser-Induced Rescattering Electrons, Junliang Xu, Zhangjin Chen, Anh-Thu Le, C. D. Lin

Physics Faculty Research & Creative Works

We study high-energy angle-resolved photoelectron spectra of molecules in strong fields. In an oscillating laser electric field, electrons released earlier in the pulse may return to recollide with the target ion, in a process similar to scattering by laboratory prepared electrons. If midinfrared lasers are used, we show that the images generated by the returning electrons are similar to images observed in typical gas-phase electron diffraction (GED). These spectra can be used to retrieve the positions of atoms in a molecule as in GED. Since infrared laser pulses of durations of a few femtoseconds are already available today, the study …

Volume 48, Number 2: September 01, 2010, University Of North Dakota

University Letter Archive

No abstract provided.

The Spinnaker [Vol. 33 No. 36], University Of North Florida

Spinnaker

Student newspaper for the UNF community.

Quantitative Imaging Reveals Heterogeneous Growth Dynamics And Treatment-Dependent Residual Tumor Distributions In A Three-Dimensional Ovarian Cancer Model, Jonathan P. Celli, Imran Rizvi, Conor L. Evans, Adnan O. Abu-Yousif, Tayyaba Hasan

Dartmouth Scholarship

Three-dimensional tumor models have emerged as valuable in vitro research tools, though the power of such systems as quantitative reporters of tumor growth and treatment response has not been adequately explored. We introduce an approach combining a 3-D model of disseminated ovarian cancer with high-throughput processing of image data for quantification of growth characteristics and cytotoxic response. We developed custom MATLAB routines to analyze longitudinally acquired dark-field microscopy images containing thousands of 3-D nodules. These data reveal a reproducible bimodal log-normal size distribution. Growth behavior is driven by migration and assembly, causing an exponential decay in spatial density concomitant with …

Submitting To The Disciplines Of Liberation: A Second Look At Mark Van Doren’S Liberal Education, Bill Koch

UNIversitas: Journal of Research, Scholarship, and Creative Activity

For a few years now I’ve been describing to colleagues in the UNI English Department some of the ways I’ve been trying to engage students with their writing in the sections of College Writing and Research that I teach, and more than once they’ve said, “I wish I could take your class.” And as I’ve continued to reread Van Doren’s 1943 book on liberal education (on which I wrote an article that was published in UNIversitas a couple years ago), I’ve found that his thoughts help me to explain some of these concepts and activities, ways to engage students …