Digital Commons Network^™

Effect Of Spatial And Temporal Variability Of Antecedent Moisture Content On Model-Generated Runoff From An Arid Watershed, William J. Meyer

UNLV Theses, Dissertations, Professional Papers, and Capstones

Streams in the arid southwest are typically ephemeral, and stream gages are not commonly available. Consequently, runoff data from storm events is not available, and flood control facility design or other water resource related decisions are based on synthetic hydrographs. In the Mojave Desert region of Southern Nevada, the duration of storm used to develop these synthetic hydrographs is the 6 hour storm. The 6 hour storm is used to simulate high intensity summer storms. Additionally, soils information used in the calculations for these synthetic hydrographs is taken from maps that are generally developed for a broad range of issues …

Acetate Causes Alcohol Hangover Headache In Rats., Christina R Maxwell, Rebecca Jay Spangenberg, Jan B Hoek, Stephen D Silberstein, Michael L Oshinsky

Department of Neurology Faculty Papers

BACKGROUND: The mechanism of veisalgia cephalgia or hangover headache is unknown. Despite a lack of mechanistic studies, there are a number of theories positing congeners, dehydration, or the ethanol metabolite acetaldehyde as causes of hangover headache.

METHODS: We used a chronic headache model to examine how pure ethanol produces increased sensitivity for nociceptive behaviors in normally hydrated rats.

RESULTS: Ethanol initially decreased sensitivity to mechanical stimuli on the face (analgesia), followed 4 to 6 hours later by inflammatory pain. Inhibiting alcohol dehydrogenase extended the analgesia whereas inhibiting aldehyde dehydrogenase decreased analgesia. Neither treatment had nociceptive effects. Direct administration of acetate …

Minimizing Base Column Demands In Multi-Story Buckling Restrained Braced Frames Using Genetic Algorithms, Christopher Hiroshi Yeates

Theses and Dissertations

Most structural optimization procedures focus on minimizing the total volume of steel in an attempt to reduce overall costs. However, many other factors can have an effect on the overall cost of a structure. Base column demands in particular, can affect base plate sizes, anchorage, and foundation design. Researchers have found that present methods for estimating column demands are too conservative. Nonlinear time history analyzes were conducted on buckling-restrained braced frames of six heights. Optimized results were found considering three ductility constraints and two optimization objectives. The two optimization objectives were minimized total brace area and minimized base column demands. …

Transcriptional Regulation Of Shigella Virulence Plasmid-Encoded Genes By Virb And Crp, Christopher Thomas Hensley

UNLV Theses, Dissertations, Professional Papers, and Capstones

Shigella flexneri is a species of Gram-negative intracellular pathogens that causes bacillary dysentery in humans. Shigella relies on the precise transcriptional regulation of virulence genes, encoded by a large virulence plasmid, for invasion and infection of human colonic epithelial cells. The transcription of most identified virulence genes are regulated through a cascade controlled by the primary regulator of virulence genes, VirF, and the global transcriptional regulator, VirB. Currently, few studies have addressed how individual Shigella virulence genes are precisely regulated for optimal expression during specific stages of pathogenesis and within the constraints of the regulatory cascade. This work addresses how …

Composite Of Complexity: Manifestations Of Whiteness And Class Among Las Vegas Italian Americans, Danielle Nicole Axt

UNLV Theses, Dissertations, Professional Papers, and Capstones

Conventional terminology and conventional boundaries, in regard to ethnicity, are no longer applicable to the ever shifting population of the United States. In specific, the various degrees of White ethnic identity does not easily transition into convenient all encompassing categories such as Caucasian or more simply, White. Whiteness studies have been at the forefront of this critique, most recently asserting that White ethnic identity is heavily influenced by context. However, although many studies are now recognizing the impact of multiple layers of White ethnic identity (along the lines of gender, locale, socioeconomic level etc.) many still neglect to identify a …

Physiological Implications Of Natural Versus Induced Arousal From Torpor, Jenifer C. Utz

UNLV Theses, Dissertations, Professional Papers, and Capstones

During the hibernation season, animals oscillate between periods of torpor and periods of interbout arousal (IBA). During torpor, body temperature is often near 0° C and metabolism is severely depressed. Oxygen consumption, a proxy for aerobic metabolism, may fall to 1% of active values. Many physiological processes including cardiovascular, respiratory, and cellular functions nearly cease. During the IBA, euthermic body temperature is restored and most systemic and cellular processes function at fully active levels. The transition period between these two physiologically dissimilar states is called arousal.

The rate of rewarming (RRW) during arousal was previously expected to progressively increase until …

The Determinants Of Colorectal Cancer Survival Disparities In Nevada, Lucas N. Wassira

UNLV Theses, Dissertations, Professional Papers, and Capstones

Different population groups across Nevada and throughout the United States suffer disproportionately from colorectal cancer and its after-effects. Overcoming cancer health disparities is important for lessening the burden of cancer. There has been an overall decline in the incidence of and mortality from colorectal cancer (CRC). This is likely due, in part, to the increasing use of screening procedures such as Fecal Occult Blood Test (FOBT) and/or endoscopy, which can reduce the risk of CRC mortality by fifty percent. Nevertheless, screening procedures are routinely used by only fifty percent of Americans aged fifty years and older. Despite overall mortality decreasing …

Classification Algorithms For Genomic Microarray, Rakesh Choudary Malepati

UNLV Theses, Dissertations, Professional Papers, and Capstones

The advent of new technologies like DNA micro-arrays provides scientists the ability to gather important information such as the expression levels of almost all the genes within a cell. As the collected data is huge, it is always necessary to use analytical methods to extract important information which can be useful in biological and medical applications. One of such applications is presented in (Van‟t Veer LJ 2002), where the authors used the gene expression values obtained from micro-arrays of breast cancer cells to predict the outcome of the disease. The prediction is based on a supervised classification. While the idea …

From ‘Baggage’ To Not ‘Non-Persons’: Levy V. Louisiana And The Struggle For Equal Rights For ‘Illegitimate’ Children, Sherrie Anne Bakelar

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study focuses on "illegitimate" children, who are more visible
than other children within the historical record because of the many laws
related to their existence. By examining this group of children, it is
possible to improve upon the framework that shapes our understanding
of childhood and provide a starting point for future studies that will
continue to illuminate children's history. Although illegitimacy laws are
as ancient as Western civilization, the key moment for the United States'
laws related to nonmarital children came in the spring of 1968 and the
pivotal decision of Levy v. Louisiana, 391 U.S. 68 (1968). …

Synthesis, Characterization And Simulation Of Optical And Raman Properties Of Metal Nanoparticles, Sriteja Yamparala

UNLV Theses, Dissertations, Professional Papers, and Capstones

Metal nanoparticles are of strong interest for their unusual optical and Raman properties with potential for new and improved device applications. Specifically, the significantly enhanced Raman Scattering enabled by Surface Plasmon Resonance on metal nanoparticles open up the potential for the implementation of very sensitive sensors. It has been demonstrated that Surface Plasmon resonance can be used for the detection of a single molecule. Out of the various metal nanoparticles that have been investigated, the most promising are that made of gold and silver. Metal nananoparticles of gold and silver show strong Raman enhancement in the visible spectral region, making …

Reconstructing Species Responses To Past Climatic Changes Using Niche Modeling And Genetic Data, Tereza Jezkova

UNLV Theses, Dissertations, Professional Papers, and Capstones

Glacial – interglacial cycles have a pronounced impact on species distributions and genetic structure. Many species shift their distributions to lower latitudes and altitudes during the colder glacial periods and expand northwards and up the elevation during warmer interglacial periods. Some species however are capable of adapting to changing environment which allows them to persist in place despite climatic changes. I explored how climatic changes after the last glacial maximum (LGM) effected two species inhabiting the deserts of western North America: one mammal (Chisel-toothed Kangaroo Rat, Dipodomys microps) and one reptile (Desert Horned Lizard, Phrynosoma platyrhinos). I used …

Bringing The Endangered Barn Owl Back To Mclean County, Illinois: Implementing A Local Nest Box Program, Anna Groves '11

Outstanding Senior Seminar Papers

Barn owls are an endangered species in Illinois, but populations have been known to increase where nest box programs have been implemented. In conjunction with the John Wesley Powell Audubon Society, a barn owl nest box program was established in McLean County and the surrounding area. Seventeen boxes are now scheduled for construction and installation this winter in the McLean County area in order to enhance existing barn owl populations, and the nest box program will continue in the future through the JWP Audubon.

Making An Impact, Stacia Momburg

Cal Poly Magazine

No abstract provided.

Alumni In The News Roundup: Fall 2010

Cal Poly Magazine

No abstract provided.

South Carolina Receives $16 Million To Improve Biomedical Research, Winthrop University

Winthrop News 2010

• The grant will provide five years of funding for SC INBRE (the IDeA Networks of Biomedical Research Excellence), a network of academic institutions working together to enhance biomedical-research infrastructure and increase competitiveness of researchers in the state.
• USC will oversee the grant and receive a fourth of the $16 million, while Winthrop will receive the second highest amount at $2.6 million.

Chemical Plume Tracing By Discrete Fourier Analysis And Particle Swarm Optimization, Eugene Jun Jie Neo, Eldin Wee Chuan Lim

Australian Security and Intelligence Conference

A novel methodology for solving the chemical plume tracing problem that utilizes data from a network of stationary sensors has been developed in this study. During a toxic chemical release and dispersion incident, the imperative need of first responders is to determine the physical location of the source of chemical release in the shortest possible time. However, the chemical plume that develops from the source of release may evolve into a highly complex distribution over the entire contaminated region, making chemical plume tracing one of the most challenging problems known to date. In this study, the discrete Fourier series method …

Water Resources Played Important Role In Patterns Of Human Settlement, New Unh Research Shows, Lori Wright

Media Relations

No abstract provided.

Attitudes About Addiction: A National Study Of Addiction Educators, Angela D. Broadus, Joyce A. Hartje, Nancy A. Roget, Kristy L. Cahoon, Samantha S. Clinkinbeard

Criminology and Criminal Justice Faculty Publications

The following study, funded by the National Institute of Drug Abuse (NIDA), utilized the Addiction Belief Inventory (ABI; Luke, Ribisl, Walton, & Davidson, 2002) to examine addiction attitudes in a national sample of U.S. college/university faculty teaching addiction-specific courses (n = 215). Results suggest that addiction educators view substance abuse as a coping mechanism rather than a moral failure, and are ambivalent about calling substance abuse or addiction a disease. Most do not support individual efficacy toward recovery, the ability to control use, or social use after treatment. Modifiers of addiction educator attitudes include level of college education; teaching …

Cell Lines Having Enhanced Cell Longevity And Protein Expression, Bruce Allen Webb, Jeremy Kroemer

Entomology Faculty Patents

It is the object of the current invention to provide methods and compositions relating to the expression of vankyrin proteins in cell lines to increase their viability, longevity and capacity for protein production. The inventors have discovered that the expression of P-ank-1 and I²-ank-3 proteins in cell culture has increased the cells' longevity and capacity for endogenous and/or heterologous target protein production. Specifically, the present invention relates to the enhanced expression of endogenous and/or heterologous target proteins/polypeptides in recombinant cells that are also expressing P-ank-1 and/or I²-ank-3 protein compared to expression host cells that are not …

Ocean Mass From Grace And Glacial Isostatic Adjustment, D. Chambers, John Wahr, Mark E. Tamisea, R Steven Nerem

Marine Science Faculty Publications

We examine geoid rates and ocean mass corrections from two published global glacial isostatic adjustment (GIA) models, both of which have been used in previous studies to estimate ocean mass trends from Gravity Recovery and Climate Experiment (GRACE) satellite gravity data. These two models are different implementations of the same ice loading history and use similar mantle viscosity profiles. The model results are compared with each other and with geoid rates determined from GRACE during August 2002 to November 2009. When averaged over the global ocean, the two models have rates that differ by nearly 1 mm yr⁻¹ of …

The Current Volume 21 : Issue 15, Nova Southeastern University

Student Newspapers

No abstract provided.

National Security: A Propositional Study To Develop Resilience Indicators As An Aid To Personnel Vetting, David Brooks, Jeff Corkill, Julie-Ann Pooley, Lynne Cohen, Cath Ferguson, Craig Harmes

Australian Security and Intelligence Conference

Within the National Security domain there is a convergence of security responsibility across the national security agencies, law enforcement and private security sectors. The sensitivity of this environment requires individuals operating in the domain to be honest, trustworthy and loyal. Personnel vetting is a formal process used to determine an individual’s suitability for access to this domain. Notwithstanding this process, significant breaches of trust, security, and corruption still occur. In psychology, resilience is a well researched phenomenon that is considered a multidimensional construct where individual attributes, family aspects and social environment interact in aiding individuals to deal with vulnerability. There …

Terrorism In Australia: A Psychometric Study Into The Western Australian Public Perception Of Terrorism, Richard Sargent, David J. Brooks

Australian Security and Intelligence Conference

Terrorism is not a new concept, as historically terrorist organisations have used the threat of violence or actual violence to generate fear in individuals, organisations and governments alike. Fear is a weapon and is used to gain political, ideological or religious objectives. Past terrorist attacks have raised concerns around the world, as governments ensured that their anti-terrorism security strategies are adequate. Domestically, Australia upgraded its capacity to respond to terrorism events through security enhancements across many areas and with new initiatives such as the 2002 public counter terrorism campaign. Nevertheless, there has been restricted research into how terrorist events have …

Characterization Of The Structure And Function Of Nucleotide Pyrophosphatase/Phosphodiesterase 7, Irene Werengekha Wanjala

Electronic Theses and Dissertations Archive

Nucleotide pyrophosphatase/phosphdiesterase (NPP) 7 , also known as alkaline sphingomyelinase (Alk-SMase) is a membrane-anchored ectoenzyme initially discovered in the intestinal tract in 1969. It is the most recently identified NPP isoform.The NPP family of enzymes currently consists of seven members, NPP1-7, numbered according to the order in which they were first associated with the NPP family.NPP enzymes hydrolyze a wide range of substrates. NPP1 and 3 are nucleotide pyrophosphatases that cleave inorganic phosphate from nucleatides and their derivatives. In contrast, NPP2, NPP6 and NPP7 are phosphodiesterases that hydrolyze phosphodiester bonds in lysolipid substrates and their derivatives. NPP4 and NPP5 are …

Requirement For Golgi-Localized Pi(4)P In Fusion Of Copii Vesicles With Golgi Compartments, Andres Lorente-Rodriguez, Charles Barlowe

Dartmouth Scholarship

The role of specific membrane lipids in transport between endoplasmic reticulum (ER) and Golgi compartments is poorly understood. Using cell-free assays that measure stages in ER-to-Golgi transport, we screened a variety of enzyme inhibitors, lipid-modifying enzymes, and lipid ligands to investigate requirements in yeast. The pleckstrin homology (PH) domain of human Fapp1, which binds phosphatidylinositol-4-phosphate (PI(4)P) specifically, was a strong and specific inhibitor of anterograde transport. Analysis of wild type and mutant PH domain proteins in addition to recombinant versions of the Sac1p phosphoinositide-phosphatase indicated that PI(4)P was required on Golgi membranes for fusion with coat protein complex II (COPII) …

Report: The Illinois State University Faculty-Staff Newsletter, November 30, 2010, Illinois State University

Illinois State University Report (1966-2012)

Illinois State University bi-weekly employee newsletter.

Fibronectin For Use In Hemostats And Wound Stabilization In Trauma, Mohammed Halhouli

Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research

Exploring the phase during wound healing when fibrinogen (FBG) and fibronectin (FN) interact forming a small thin layer for cells to migrate and proliferate at the injury site is necessary for the primary building blocks and initial stages of skin recovery. The aim of this thesis is to illustrate that administrating a reasonable amount of (FN) and FBG, in a semi-organizational technique, to the wound site will encourage cell population and ECM formation, as well as, improve the wound healing process. WE hypothesized that FBG and FN interactions will configure the construction of dermal cells and their final fate to …

Effects Of Dietary Choline, Folic Acid And Vitamin B12 On Laying Hen Performance, Egg Components And Egg Phospholipid Composition, Pradeep Krishnan Rajalekshmy

Department of Animal Science: Dissertations, Theses, and Student Research

In trial 1, a corn-soy basal diet was formulated with three levels of supplemental choline (0, 500 and 1000 ppm) and three levels of supplemental folic acid (0, 2 and 4 ppm) in a 3 x 3 factorial arrangement. Folic acid at 2 ppm increased egg production (p ≤ 0.04). Egg wt was higher at 500 ppm of choline (p ≤ 0.06) and 0 ppm (p ≤ 0.01) of folic acid supplementation. There were choline by folic acid interaction effects on feed intake (p ≤ 0.001), albumen wt (p ≤ 0.005) and yolk wt ( …

Peptidomimetic Inhibitors Of Stat Activity And Uses Thereof, James Turkson, Richard Jove, Said M. Sebti, Andrew D. Hamilton

USF Patents

The subject invention concerns compositions and methods for blocking cancer cell growth or proliferation and/or inducing cancer cell death. Compositions of the present invention are peptidomimetics that inhibit STAT function. Peptidomimetics of the invention include compounds of the formula RY*L (where Y* represents phosphotyrosine), with the R group at the Y-1 position. Peptidomimetics of the invention disrupt Stat3 activation and function. Peptidomimetics of the invention significantly inhibit tumor cell growth and induce tumor cell death.

Phytoremediation Of Copper Contaminated Waste Water Using Lemna Minor, Mark Apelt

Theses and Dissertations

The use of natural remediation methods to remove contaminants from waste water is becoming more popular. Plants have been used for several decades, yet their use for municipal waste water contaminated by heavy metals is limited to a few studies which focus on the Mercury and Chromium (Bennicelli, et.al, 2004). This study specifically attempted to determine the viability for using Lemna minor to remediate municipally generated wastewater contaminated with copper. The study used 100 ml samples of wastewater, artificially spiked with 8 mg/L of copper sulfate and seeded with approximately 100 Lemna minor fronds. Each treatment was repeated 15 times …