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Supplemental Schedules For The Year Ended June 30, 2009, Clemson University

Annual Comprehensive Financial Report

No abstract provided.

The C8 Health Project: Design, Methods, And Participants, Stephanie J. Frisbee, A Paul Brooks Jr, Arthur Maher, Patsy Flesborg, Susan Arnold, Tony Fletcher, Kyle Steenland, Anoop Shankar, Sarah S. Knox, Cecil Pollard, Joel A. Halverson, Veronica M. Vieira, Chuanfang Jin, Kevin M. Leyden, Alan M. Ducatman

Faculty & Staff Scholarship

Background

The C8 Health Project was created, authorized, and funded as part of the settlement agreement reached in the case of Jack W. Leach, et al. v. E.I. du Pont de Nemours & Company (no. 01-C-608 W.Va., Wood County Circuit Court, filed 10 April 2002). The settlement stemmed from the perfluorooctanoic acid (PFOA, or C8) contamination of drinking water in six water districts in two states near the DuPont Washington Works facility near Parkersburg, West Virginia.

Objectives

This study reports on the methods and results from the C8 Health Project, a population study created to gather data that would allow …

Scholarworks Statistics - January 2010, Scholarworks

ScholarWorks Reports

For the month of January 2010, ScholarWorks recorded a total of 2297 full-text downloads.

Can Weak Substitution Be Rehabilitated?, V. Kerry Smith, Mary F. Evans, H. Spencer Banzhaf, Christine Poulos

CMC Faculty Publications and Research

This paper develops a graphical analysis and an analytical model that demonstrate how weak substitution can be used for non-market valuation. Weak complementarity and weak substitution represent preference restrictions that allow us to develop equivalent price changes to describe quantity or quality changes in non-market goods. The price changes are Hicksian equivalents in that they yield the same utility changes as would the quantity or quality changes. After discussion of several potential applications of weak substitution, the paper develops the parallel between the restriction and recent strategies from modeling differentiated goods.

Malondialdehyde–Acetaldehyde Adduct Is The Dominant Epitope After Mda Modification Of Proteins In Atherosclerosis, Michael J. Duryee, Lynell W. Klassen, Courtney S. Schaffert, Dean J. Tuma, Carlos Hunter, Robert P. Garvin, Daniel R. Anderson, Geoffrey M. Thiele

United States Department of Veterans Affairs: Publications

Antibodies to malondialdehyde (MDA)-modified macromolecules (adducts) have been detected in the serum of patients with atherosclerosis and correlate with the progression of this disease. However, the epitope and its formation have not been characterized. Studies have shown that excess MDA can be degraded to acetaldehyde, which combines with proteins to from a stable dihydropyridine adduct. To investigate, mice were immunized with MDA adducts in the absence of adjuvant and showed an increase in antibodies to MDA adducts and the carrier protein as the concentration of MDA was increased. In fact, a number of the commercially available antibodies to MDA-modified proteins …

The Economic Impact Of The University Of Arkansas, Katherine A. Deck, Viktoria Riiman

Publications and Presentations

Founded in 1871, the University of Arkansas was established in the city of Fayetteville as both the state university and the major land‐grant university for Arkansas. The University of Arkansas is a flagship university for the integration of student engagement, scholarship and research, and innovation that collectively transforms lives and inspires leadership for a global society. As such, the impact of the University of Arkansas extends far beyond the transfer of knowledge from professors to students and is far reaching in social and economic terms. As leading research universities across the country engage in the process of enumerating the socio‐economic …

Development Of An Educational Resource Tool To Improve Hospital Wide Knowledge Of Rehabilitation Care And Services, Vickey R. Allen

Nursing Theses and Capstone Projects

Health Care Organizations (HCO) are businesses. In an effort to be successful and to remain viable, HCOs must provide a myriad of services to meet their customer's needs. Included in these services is competent rehabilitation care that manages patients holistically. Utilizing Orem's theory of self care deficit, this project will demonstrate the growing need for rehabilitation services and the importance of all healthcare providers to understand the profession in general. In addition, this project will provide a resource tool to educate healthcare workers and others; students and non-licensed personnel, on the care and services patients receive during their stay in …

What Are The Perceptions Of Hispanic Parents Associated With Eating Habits Of Hispanic Children Ages 6--12 And Obesity?, Amy Barrett

Nursing Theses and Capstone Projects

The main objective of this study is to identify the perceptions of Hispanic parents associated with eating habits of Hispanic children ages 6-12 and obesity. The purpose was to identify if the child's intake was different based on the parent's perception of whether or not their child had a weight problem. The idea was to examine how many times certain foods are consumed and compare that to the parent's perceptions. The study was a descriptive study. The childrenhad to be in the 95 th percentile and between the ages of 6-12 to qualify for the study. Parents were approached by …

Nursing Attitudes Towards Obese Patients, Diane M. Davis

Nursing Theses and Capstone Projects

All Registered Nurses and Licensed Practical Nurses who work in CICU, MSICU, NTICU and 7N .The attitudes of these nurses regarding obesity and the obese patients were measured. Objectives. To determine if there is a bias against obese patients in the health care setting and if further education is needed. Methods. Likert scale survey, modified from the NATOOPS survey (with permission) was sent electronically to each nurse and when completed transmitted to a data base where results were tabulated. Results. Among the 51 respondents, 60% had 4 years of college or more. Years in nursing ranged from 0-47.Age of nurse …

The Leading Object:March 2010, John C. Owens

Leading Object

Perspectives; INTSORMIL helps improve varieties of grains in developing countries; Engler’s donation to support agribusiness entrepreneurship; Career with Monsanto proves fulfilling; State ranks high during National Ag Week; CARET delegates support IANR; Lindgren retires from UNL after 34 years; Masek given March KUDO award; McAndrew receives service award; Vet sciences building gets new name; Fritz accepted into leadership program

Common Factors Predicting Long-Term Changes In Multiple Health Behaviors, Bryan J. Blissmer, James O. Prochaska, Wayne F. Velicer, Colleen A. Redding, Joseph S. Rossi, Geoffrey W. Greene, Andrea L. Paiva, Mark L. Robbins

Cancer Prevention Research Center Faculty Publications

This study was designed to assess if there are consistent treatment, stage, severity, effort and demographic effects which predict long-term changes across the multiple behaviors of smoking, diet and sun exposure. A secondary data analysis integrated data from four studies on smoking cessation (N = 3927), three studies on diet (N = 4824) and four studies on sun exposure (N = 6465). Across all three behaviors, behavior change at 24 months was related to treatment, stage of change, problem severity and effort effects measured at baseline. There were no consistent demographic effects. Across multiple behaviors, long-term behavior …

Land Use And Climatic Factors Structure Regional Patterns In Soil Microbialcommunities, Rebecca E. Drenovsky, Kerri L. Steenworth, Louise E. Jackson, Kate M. Scow

Biology

Aim Although patterns are emerging for macroorganisms, we have limited under- standing of the factors determining soil microbial community composition and productivity at large spatial extents. The overall objective of this study was to discern the drivers of microbial community composition at the extent of biogeo- graphical provinces and regions. We hypothesized that factors associated with land use and climate would drive soil microbial community composition and biomass. Location Great Basin Province, Desert Province and California Floristic Province, California, USA. Methods Using phospholipid fatty acid analysis, we compared microbial com- munities across eight land-use types sampled throughout the State of …

Using Disability Law To Protect Persons Living With Hiv/Aids: The Indian And American Approach, Pamela Koehler

Florida State University Journal of Transnational Law & Policy

HIV/AIDS in India continues to be a growing problem for the subcontinent as well as for the rest of the world. Because India has emerged as a global economic player and is the second most populous country in the world, devastation from HI V/AIDS in the region could have far-reaching global ramifications. The protection of civil liberties and elimination of discrimination is critical to any sustainable public health strategy. This article looks specifically at India's Persons with Disabilities Act (PWDA) as a potential tool in addressing HIV/AIDS discrimination. Disability law, as a mechanism for protecting persons living with HIV/AIDS, remains …

Empirical Evidence And The Case For Foreign Aid, Nicole Hassoun

Philosophy Faculty Scholarship

This paper addresses an important methodological question for a recent debate in global justice: What types of data are necessary for settling normative debates about foreign aid? Recently, several philosophers have considered the case for foreign aid and have concluded that foreign aid is either ineffective or counter-productive. This paper considers what kinds of evidence those doing applied philosophy must use to support different claims about aid’s efficacy. Then, using some of the best available data, this paper makes a strong case for at least some foreign aid. This paper’s methodological lessons, however, are quite general. It considers what types …

The Cuban Embargo: Detrimental To Cuba, The United States, And Democracy, Mcclain Napier

Sigma: Journal of Political and International Studies

No abstract provided.

Evaluating An Insurance-Sponsored Weight Management Program With The Re-Aim Model, West Virginia, 2004-2008, Christiaan Abildso, Sam Zizzi, Bill Reger-Nash

Faculty & Staff Scholarship

Introduction: Evaluations of weight management programs in real-world settings are lacking. The RE-AIM model (reach, effectiveness, adoption, implementation, maintenance) was developed to address this deficiency. Our primary objective was to evaluate a 12-week insurance-sponsored weight management intervention by using the RE-AIM model, including short-term and long-term individual outcomes and setting-level implementation factors. Our secondary objective was to critique the RE-AIM model and its revised calculation methods.

Methods: We created operational definitions for components of the 5 RE-AIM indices and used standardized effect size values from various statistical procedures to measure multiple components or outcomes within each index. We used chi(2) …

Characterization Of The Rainbow Trout Transcriptome Using Sanger And 454-Pyrosequencing Approaches, Mohamed Salem, Caird E. Rexroad Iii, Jiannan Wang, Gary H. Thorgaard, Jianbo Yao

Faculty & Staff Scholarship

Background

Rainbow trout are important fish for aquaculture and recreational fisheries and serves as a model species for research investigations associated with carcinogenesis, comparative immunology, toxicology and evolutionary biology. However, to date there is no genome reference sequence to facilitate the development of molecular technologies that utilize high-throughput characterizations of gene expression and genetic variation. Alternatively, transcriptome sequencing is a rapid and efficient means for gene discovery and genetic marker development. Although a large number (258,973) of EST sequences are publicly available, the nature of rainbow trout duplicated genome hinders assembly and complicates annotation.

Results

High-throughput deep sequencing of the …

Maternal Low-Level Lead Exposure And Fetal Growth, Motao Zhu, Edward F. Fitzgerald, Kitty H. Gelberg, Shao Lin, Charlotte M. Druschel

Faculty & Staff Scholarship

Background

Limited epidemiologic studies have examined the association between maternal low-level lead exposure [blood lead (PbB) < 10 μg/dL] and fetal growth.

Objective

We examined whether maternal low-level lead exposure is associated with decreased fetal growth.

Methods

We linked New York State Heavy Metals Registry records of women who had PbB measurements with birth certificates to identify 43,288 mother–infant pairs in upstate New York in a retrospective cohort study from 2003 through 2005. We used multiple linear regression with fractional polynomials and logistic regression to relate birth weight, preterm delivery, and small for gestational age to PbB levels, adjusting for potential confounders. We used a closed-test …

Self-Reported Dental Hygiene, Obesity, And Systemic Inflammation In A Pediatric Rural Community Cohort, Stephanie J. Frisbee, Christopher B. Chambers, Jefferson C. Frisbee, Adam G. Goodwill, Richard J. Crout

Faculty & Staff Scholarship

Background

A growing body of epidemiologic evidence links oral health, obesity, and cardiovascular health, though few studies have reported on these relationships in children. While underlying mechanisms are unclear, adult studies have suggested sub-acute systemic inflammation, also implicated in the etiology of both obesity and cardiovascular disease. This study investigated associations between self-reported dental hygiene, obesity, and systemic inflammation in children.

Methods

128 children < 19 years of age from rural counties in West Virginia participated in a community-based health screening that included anthropometric assessments, blood collection, and a questionnaire about dental hygiene and self-assessed oral health.

Results

Participants ranged from 3.0-18.7 years. Univariate analysis demonstrated an association between parent-reported dental hygiene, including frequency of preventive dental care and parent-assessed overall dental health, and markers of systemic inflammation but not obesity. In multivariable …

Agt M235t Genotype/Anxiety Interaction And Gender In The Hypergen Study, Sarah S. Knox, Xinxin Guo, Yuqing Zhang, G Weidner, Scott Williams, R Curtis Ellison

Faculty & Staff Scholarship

Background

Both anxiety and elevated heart rate (HR) have been implicated in the development of hypertension. The HyperGen cohort, consisting of siblings with severe and mild hypertension, an age-matched random sample of persons from the same base populations, and unmedicated adult offspring of the hypertensive siblings (N = 1,002 men and 987 women), was analyzed for an association of the angiotenisinogen AGTM235T genotype (TT, MT, MM) with an endophenotype, heart rate (HR) in high and low anxious groups.

Methodology

The interaction of AGTM genotype with anxiety, which has been independently associated with hypertension, was investigated adjusting for age, hypertension status, …

A Mixed-Method Evaluation Of A College Student Fitness Program Using The Re-Aim Framework, Michelle L. Bartlett, Sam Zizzi

Faculty & Staff Scholarship

Background: The consistently rising obesity rate in college student population illustrates the need for organized and effective interventions. The purposes of this study were to evaluate an eight-week fitness program implemented at university student recreation center using mixed-methods along the reach, effectiveness, and implementation dimensions of the RE-AIM framework for evaluating health-promotion programs and to illustrate how qualitative data can be used to enhance the capabilities of the RE-AIM framework to evaluate such programs via providing recommendations to improve the intervention not possible with just a quantitative RE-AIM evaluation. Methods: Quantitative (participation rate, changes in % body fat, and resting …

Association Of Perfluorooctanoic Acid (Pfoa) And Perfluorooctane Sulfonate (Pfos) With Uric Acid Among Adults With Elevated Community Exposure To Pfoa, Kyle Steenland, Sarah Tinker, Anoop Shankar, Alan Ducatman

Faculty & Staff Scholarship

Background

Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are compounds that do not occur in nature, have been widely used since World War II, and persist indefinitely in most environments. Median serum levels in the United States are 4 ng/mL for PFOA and 21 ng/mL for PFOS. PFOA has been associated with elevated uric acid in two studies of chemical workers. Uric acid is a risk factor for hypertension and possibly other cardiovascular outcomes.

Methods

We conducted a cross-sectional study of PFOA and PFOS and uric acid among 54,951 adult community residents in Ohio and West Virginia, who lived or …

Efficacy And Safety Of A New Formulation Of Pancrelipase (Ultrase Mt20) In The Treatment Of Malabsorption In Exocrine Pancreatic Insufficiency In Cystic Fibrosis, Michael W. Konstan, Theodore G. Liou, Steven D. Strausbaugh, Richard Ahrens, Jamshed F. Kanga, Gavin R. Graff, Kathryn Moffett, Susan L. Millard, Samya Z. Nasr, Edith Simeon, Jean Spenard, Josee Grondin

Faculty & Staff Scholarship

Background. Pancreatic enzyme replacement therapy is the standard of care for treatment of malabsorption in patients with cystic fibrosis (CF) and exocrine pancreatic insufficiency (PI). Aim. To evaluate efficacy and safety of a new formulation of pancrelipase (Ultrase MT20) in patients with CF and PI. Coefficients of fat absorption (CFA%) and nitrogen absorption (CNA%) were the main efficacy parameters. Safety was evaluated by monitoring laboratory analyses, adverse events (AEs), and overall signs and symptoms. Methods. Patients () were randomized in a crossover design comparing this pancrelipase with placebo during 2 inpatient evaluation periods (6-7 days each). Fat and protein/nitrogen ingestion …

A Model For Transgenerational Imprinting Variation In Complex Traits, Chenguang Wang, Zhong Wang, Jiangtao Luo, Qin Li, Yao Li, Kwangmi Ahn, Daniel R. Prows, Rongling Wu

Faculty & Staff Scholarship

Despite the fact that genetic imprinting, i.e., differential expression of the same allele due to its different parental origins, plays a pivotal role in controlling complex traits or diseases, the origin, action and transmission mode of imprinted genes have still remained largely unexplored. We present a new strategy for studying these properties of genetic imprinting with a two-stage reciprocal F mating design, initiated with two contrasting inbred lines. This strategy maps quantitative trait loci that are imprinted (i.e., iQTLs) based on their segregation and transmission across different generations. By incorporating the allelic configuration of an iQTL genotype into a mixture …

Evolution Of The Florida State University Coastal And Marine Laboratory, Michael J. Greenberg, William F. Herrnkind, Felicia C. Coleman

Gulf of Mexico Science

No abstract provided.

Balancing Consumer Protection And Scientific Integrity In The Face Of Uncertainty: The Example Of Gluten-Free Foods, Margaret Sova Mccabe

Law Faculty Scholarship

In 2009, gluten-free foods were not only "hot" in the marketplace, several countries, including the United States, continued efforts to define gluten-free and appropriate labeling parameters. The regulatory process illuminates how difficult regulations based on safe scientific thresholds can be for regulators, manufacturers and consumers. This article analyzes the gluten-free regulatory landscape, challenges to defining a safe gluten threshold, and how consumers might need more label information beyond the term "gluten-free." The article includes an overview of international gluten-free regulations, the Food and Drug Administration (FDA) rulemaking process, and issues for consumers.

Bloodsucking Copyrights, Ann Bartow

Law Faculty Scholarship

Some bloodsuckers live off the life-sustaining fluids of involuntary hosts and leave behind diseases or venom. Fleas, ticks, bedbugs, and mosquitoes are all bloodsuckers that are best avoided. Others, like the leech, suck blood in ways that can be very helpful to a host, promoting blood flow and healing. Vampires are fictional, sentient bloodsuckers that have populated various entertainment genres for centuries. Copyrights, too, can suck blood metaphorically in productive and destructive ways, or simply suck, period, when they senselessly impede free-flowing veins of information. And though they are not (yet) immortal, copyrights last a very long time. In Copyright’s …

Governance, Accountability And The New Poverty Agenda, Wendy A. Bach

Scholarly Works

Across the country a new poverty agenda is emerging. These efforts are limited by the political consensus that has emerged since welfare reform and focus, as has always been the case, on the “deserving” - in today’s iteration, primarily the working poor. Mirroring national and international trends, the means of governance of these new social welfare programs has also begun to change. Where once there was a set of programs ostensibly controlled through law and regulations, in growing pockets there is now radical devolution and abandonment of traditional legal and rule making structures. Experiments in policy, program structure, and governance …

Board Of Regents Meeting Materials, September 21, 2010, Eastern Michigan University

Board of Regents Meeting Materials

No abstract provided.

2009 Cancer Care Annual Report, Children's Mercy Hospital

Cancer Center Annual Reports

Annual report of cancer care and oncology services at the Children's Mercy Hospital, Kansas City MO, a pediatric medical center. This report has a focus on acute lymphoblastic leukemia.