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Oncolog Volume 55, Number 06, June 2010, John Lebas

OncoLog MD Anderson's Report to Physicians (All issues) Archives

• The BATTLE Results Are IN: Phase II trial reveals molecular signatures in lung cancer that may guide treatment decisions.
• Endoscopic Repair of Colon Perforations: Nonsurgical techniques for closing gestrointestinal defects may yiels benefits for patients undergoing colonoscopy.
• INBRIEF: Stem Cells Seen Repairing Heart Attack Damage Over Time/Additional Blood Data May Improve Pediatric Leukemia Predictions/Pediatric Patients with Rare Tumor May benefit from Heated Chemotherapy/New Findings Refute Link Between UVA, Melanoma.
• HOUSE CALL: Skin Cancer Screening: What is It and Who Should Get It ?: Types of skin cancer/Who should be screened ?/What to expect/Self-examination: Check your skin regularly and tell your …

Manual: Blue Cross And Blue Shield Of Florida Foundation- June 2010-March 2011 Media Placements, Blue Cross And Blue Shield Of Florida, Inc.

Florida Blue Archives Printed Materials

A manual for the Blue Cross and Blue Shield of Florida Foundation Media Placements for June 2010 - March 2011.

War Paths, Peace Paths: An Archaeology Of Cooperation And Conflict In Native Eastern North America, By David H. Dye, Charles R. Cobb

Faculty Publications

A review of War Paths, Peace Paths: an Archaeology of Cooperation and Conflict in Native Eastern North America, by David H. Dye.

Insuring Against Drought‐Related Livestock Mortality: Piloting Index Based Livestock Insurance In Northern Kenya, Andrew G. Mude, Sommarat Chantarat, Christopher B. Barrett, Michael R. Carter, Munenobu Ikegami, John G. Mcpeak

Economics - All Scholarship

Climate related shocks are among the leading cause of production and efficiency losses in smallholder crop and livestock production in rural Africa. Consequently, the identification of tools to help manage the risks associated with climactic extremities is increasingly considered to be amongst the key pillars of any agenda to enhance agricultural growth and welfare in rural Africa. This paper describes the application of a promising innovation in insurance design – index‐based insurance – that seeks to bring the benefits of formal insurance to help manage the weather‐related risks faced by rural crop and livestock producers in low‐income countries. In particular, …

Prevalence Of Obesity, Type Ii Diabetes Mellitus, Hyperlipidemia, And Hypertension In The United States: Findings From The Ge Centricity Electronic Medical Record Database., Albert G Crawford, Christine Cote, Joseph Couto, Mehmet Daskiran, Candace Gunnarsson, Kara Haas, Sara Haas, Somesh C Nigam, Rob Schuette

College of Population Health Faculty Papers

This study analyzed GE Centricity Electronic Medical Record (EMR) data to examine the effects of body mass index (BMI) and obesity, key risk factor components of metabolic syndrome, on the prevalence of 3 chronic diseases: type II diabetes mellitus, hyperlipidemia, and hypertension. These chronic diseases occur with high prevalence and impose high disease burdens. The rationale for using Centricity EMR data is 2-fold. First, EMRs may be a good source of BMI/obesity data, which are often underreported in surveys and administrative databases. Second, EMRs provide an ideal means to track variables over time and, thus, allow longitudinal analyses of relationships …

Skew Selection Theory Applied To The Wealth And Welfare Of Nations, Susan F. Allen, Deby L. Cassill

The Journal of Sociology & Social Welfare

According to skew selection theory, working citizens who build wealth and, at the same time, share portions of their wealth with those in need are more likely to survive economic downturns than citizens who hoard wealth. In this article, skew selection is employed as a theoreticalframework to support governmental efforts to develop social policies that protect the income of working citizens and, at the same time, provide for vulnerable, non-working children and elders. To illustrate its applicability, the social policies of Japan, Sweden and the United States-all of which are challenged by decaying ratios of working to non-working citizens-are compared …

Energy Harvesting From Exercise Machines Cal Poly Recreation Center Implementation, Justin Arakaki, Praveen Lawrence, Audrey Nakamura

Electrical Engineering

As Cal Poly moves towards an environmentally friendly campus, the Energy Harvesting from Exercise Machines (EHFEM) project looks to generate a new source of renewable energy to help power the Cal Poly Recreation Center. The project focuses on retrofitting exercise machines to generate electricity. As of December 2009, Audrey Nakamura, Justin Arakaki, and Praveen Lawrence developed a design which allows the contribution of electricity generated from multiple exercise machines into the power grid.

The project will require an investigation of retrofitted machine designs by Cal Poly students and commercially available products and systems. The information obtained from the product research …

The Effects Of Public Infrastructure And Household Characteristics On Inequality And Infant Mortality In Mexico: What Has Changed Between 1990 And 2005?, Richard S. Meindl, Jose Antonio Roldan Amaro, Cynthia Thompson, Tremaine L. Gregory, Marcela Alvarez Izazaga, Gabriel Saucedo Arteaga

Peer Reviewed Articles

The reduction of infant mortality (IM) continues to be a primary goal throughout much of the developing world, and a suite of methods have been proposed with which to achieve it. However, most attempts at IM reduction have taken place within the context of an almost bewilderingly complex regimen of simultaneous changes occurring in the physical environment, sociopolitical structure, and health care. Which of these various elements is truly causal in reducing IM and which may be merely a correlated but nonprimary agent? During the past two decades Mexico has constituted an extraordinary field laboratory with which to decipher the …

Commencement Program 2010, Loma Linda University

Commencement Programs

CONTENTS

1 | Message from the President

3 | 2010 Events of Commencement

4 | The Academic Procession

6 | Significance of Academic Regalia

8 | The Good Samaritan

9 | University History Highlights

11 | Loma Linda University Song - "Healing Love"

12 | The Speakers

22 | The University Honorees

36 | The School Honorees

59 | The Programs

• School of Medicine, 60
• School of Pharmacy, 77
• School of Dentistry, 83
• School of Science and Technology and School of Religion, 99
• School of Nursing, 112
• School of Allied Health Professions - Physical Therapy, 121
• School of Allied Health …

A Joan Cadden Bibliography, Chris Africa

Medieval Feminist Forum: A Journal of Gender and Sexuality

No abstract provided.

Impact Of Dbt Treatment On The Relationship Between Women’S Overall Self-Concept And Body-Image, Rachel Mueller

Doctor of Psychology (PsyD)

Given the connection between self-concept and body-image for women recovering from eating disorders, this study researched the impact of twelve women’s participation in a body- image group in a Dialectical Behavior Therapy Center. The dialectical behavior therapy approach is of particular interest given its emphasis on mindfulness and acceptance, which may aid in decreasing the tension between how women with eating disorders view their ideal versus perceived selves. Quantitatively, this study investigated change in scores on the Total Self- concept Score (TOT) and Conflict Score (CON) of the Tennessee Self-concept Scale – 2. As hypothesized, data analysis revealed a large …

Modeling The Differential Incidence Of "Child Abuse, Neglect And Exploitation" In Poor Households In South Africa: Focus On Child Trafficking, Paulin Mbecke

African Journal of Criminology and Justice Studies

This paper is based on an in-progress Ph.D. research 2 themed: “Modeling the Differential Incidence of Child Abuse, Neglect and Exploitation in Poor Households in South Africa”. The aim of the research is to build a theoretical grounding and to propose a practical model for understanding child abuse. The research argues that the gaps and shortcomings in understanding child abuse are, to a large extent, the consequence of an over-estimation of socio-economic variables as main variables contributing to the incidence of child abuse. The paper does not attempt to collect data on child trafficking to explain its extent in South …

Chemical Inhibition Of Caax Protease Activity Disrupts Yeast Ras Localization, Surya P. Mandahar, Emily R. Hildebrandt, William H. Jacobsen, George M. Santangelo, Walter K. Schmidt

Faculty Publications

Proteins possessing a C-terminal CaaX motif, such as the Ras GTPases, undergo extensive post-translational modification that includes attachment of an isoprenoid lipid, proteolytic processing and carboxylmethylation. Inhibition of the enzymes involved in these processes is considered a cancer-therapeutic strategy. We previously identified nine in vitro inhibitors of the yeast CaaX protease Rce1p in a chemical library screen (Manandhar et al., 2007). Here, we demonstrate that these agents disrupt the normal plasma membrane distribution of yeast GFP-Ras reporters in a manner that pharmacologically phenocopies effects observed upon genetic loss of CaaX protease function. Consistent with Rce1p being the in vivo target …

Environmental Variables Influencing The Severity Of Pierce's Disease In California Grapevines, Christopher James Boisseranc

Master's Theses

This project was designed to correlate environmental variables with the development of Pierce’s Disease (PD), an infection caused by the gram negative bacterium Xylella fastidiosa (Xf), in grapes (Hopkins et al. 2002). PD is one of the most difficult crop pathogens to manage because it is vectored by insects and its continued presence in the vine is usually fatal. PD is influenced by the interaction of host, disease and vector, and probably many other environmental variables. The general objective was to study and identify the most important variables involved in the expression of Pierce’s Disease.

Over a two year period, …

Evaluation Of Patients' Knowledge On Warfarin In Outpatient Anticoagulation Clinics In A Teaching Hospital In Qatar, Imran F. Khudair, Yolande I. Hanssens

Saudi Medical Journal

OBJECTIVE: To evaluate the extent and quality of the patient9s education on warfarin and its possible impact on the international normalized ratio (INR). METHODS: This is a cross-sectional study using a 20-item, self administered questionnaire of knowledge, offered to patients who were taking warfarin for at least 2 months and attending the medical or cardiology anticoagulation clinics in Hamad General Hospital, Hamad Medical Corporation, State of Qatar between August 2008 to November 2008. RESULTS: A total of 140 patients completed the questionnaire, 116 patients (83%) reported that they received warfarin education and 61 patients (44%) had a controlled INR. Of …

Bjc Today

BJC Today

No abstract provided.

Hypoxia And Fetal Programming Of Cardiovascular Dysfunction, Qin Xue

Loma Linda University Electronic Theses, Dissertations & Projects

Human epidemiological studies have shown a clear association of adverse intrauterine environment and an increased risk of ischemic heart disease in later adult life. Of all the stresses to which the fetus is subjected, perhaps the most important and clinically relevant is that of hypoxia. The goal of this project is to test the hypothesis that chronic hypoxia during gestation adversely affects fetal cardiovascular development and impairs cardiac function in offspring. In the first part of project, we tested the hypothesis that chronic hypoxia adversely regulates contractility of fetal pulmonary arteries and veins in sheep residing at high altitude (3,801 …

Mental Health And Victimization Experiences In Fibromyalgia: A Literature Review, Eric J. Kloeppel

Loma Linda University Electronic Theses, Dissertations & Projects

Fibromyalgia (FM) is a chronic disorder characterized by widespread musculoskeletal pain, fatigue, and/or multiple tender points located on the neck, shoulders, back, hips, arms or legs that hurt when touched. FM can be a debilitating condition with financial, emotional, interpersonal, and health costs that can affect not only the person diagnosed, but his or her family and friends. Presently, the etiology of FM is largely unknown and there is no definitive cure. Researchers have identified several possible contributing factors in the development and maintenance of FM, including genetics, abnormalities in the neuroendocrine system, and sleep disturbances as well as psychiatric …

Association Between Obesity, Depression, And Inflammation Among Seventh-Day Adventists In The Biopsychosocial Religion And Health Study, Michael Paalani

Loma Linda University Electronic Theses, Dissertations & Projects

The effects of obesity and depression on morbidity and mortality may be mediated by inflammatory processes. Homeostasis within the immune system depends on a balance of pro-inflammatory and anti-inflammatory cytokine molecules, so chronic inflammatory diseases may result from cytokine dysregulation. The target population consisted of 508 Seventh Day Adventists (SDAs) who participated in the Biopsychosocial Religion and Health Study (BHRS), a sub-study of the Adventist Health Study-2. The study was a cross-sectional analysis of the association between obesity, depression, and inflammation after controlling for demographic, socioeconomic, health behavioral, and health status variables among BHRS participants.

Obesity was assessed by body …

Aerobic Exercise And Bone Turnover In Trained And Untrained Premenopausal Women, Michelle Prowse

Loma Linda University Electronic Theses, Dissertations & Projects

Regular weight-bearing exercise is recommended for healthy young adults to optimize bone mineral density (BMD) (Physical Activity Guidelines Advisory Committee, 2008). BMD alone however, is not a significant predictor of osteoporosis or fracture risk. While bone turnover markers are used clinically to assess efficacy of pharmacological intervention in individuals diagnosed with osteoporosis, they may also have a role in evaluating acute responses to exercise. The purpose of this dissertation was to compare two groups of premenopausal women, those which are sedentary (low fitness) versus those that are well-trained (high fitness), by BMD and bone turnover markers at rest and the …

Fetal Programming By Nicotine Increases Cardiac Susceptibility To Ischemic Injury, Jennifer Charlotte Alexie Lawrence

Loma Linda University Electronic Theses, Dissertations & Projects

Fetal programming is the area of study that focuses on the prenatal origins of adult onset disorders. Previous studies have associated an adverse prenatal environment with the onset of physiologic and metabolic diseases during adulthood. Fetal malnutrition, hypoxia, and exposure to drugs - such as cocaine and nicotine - have been associated with adult disease states. Cigarette smoking is the number one cause of preventable death in the developed world. Among the many dangerous chemicals found in tobacco products is nicotine, the compound responsible for the addictive nature of tobacco use. Nicotine use during pregnancy is a known cause of …

Mechanisms Of Dha Neuroprotection From Pa Induced Lipotoxieity, Frankis G. Almaguel

Loma Linda University Electronic Theses, Dissertations & Projects

Initially in our study, we evaluated the effect of PA on NGF Differentiated PC 12 cells at concentrations levels that mimic pathological conditions. PA exposure resulted to be toxic to NGFDPC12 cells. PA treatment decreased cell viability and triggered cell death with apparent apoptotic features. Further morphological studies revealed the classical features of apoptosis response; including cell shrinking, cell blebbing, chromatin and nucleus condensation (Kerr et al. 1972). Our findings in summary, suggest that FFA-induced lipotoxicity requires full activation of PA, targeting the mitochondria, leading to membrane potential disruption and up-regulation of reactive oxygen free radicals. PA-induced-lipotoxicity decreased cell viability …

Psychosocial Factors Associated With Nicotine Dependence Among College Students : Are There Differences Between Social And Regular Smokers?, Devan Rae Romero

Loma Linda University Electronic Theses, Dissertations & Projects

Background. Cigarette smoking, the primary source of tobacco used by adults 18-25, has remained stable, at around 21-25%, in the college population since 2003. Many college students report their smoking as primarily a “social” behavior, which may reflect an emerging type of smoker. Ambiguity exists in defining and categorizing smokers in the college population.

Purpose. The purpose of this study was to examine psychosocial perceptions related to smoking among college students who currently smoke and those who do not smoke, and among different types of smokers. In addition, validation of self-reported smoking behavior with saliva cotinine was conducted in …

Optimal Technical Management Of Stump Closure Following Distal Pancreatectomy: A Retrospective Review Of 215 Cases., Lisa J. Harris, Hamid Abdollahi, Timothy Newhook, Patricia K. Sauter, Albert G. Crawford, Karen A. Chojnacki, Ernest L. Rosato, Eugene P. Kennedy, Charles J. Yeo, Adam C. Berger

Department of Surgery Faculty Papers

BACKGROUND: Pancreatic fistula (PF) is a major source of morbidity following distal pancreatectomy (DP). Our aim was to identify risk factors related to PF following DP and to determine the impact of technique of transection and stump closure.

METHODS: We performed a retrospective review of 215 consecutive patients who underwent DP. Perioperative and postoperative data were collected and analyzed with attention to PF as defined by the International Study Group of Pancreatic Fistula.

RESULTS: PF developed in 36 patients (16.7%); fistulas were classified as Grade A (44.4%), B (44.4%), or C (11.1%). The pancreas was transected with stapler (n = …

Global Warming: Myths & Realities, Dennis Jaynes

Social Sciences

The topic of Global Warming has been surrounded with controversy since it was first proposed. From evidence that has come from years of studies, a majority of the world’s governments and scientists are in agreement that the Earth’s global temperatures are warming. However, there are others who are skeptical of the science; they spread their message by trying to discredit the scientists or have even gone as far as to cover it up. The intent of this paper is to examine the myths and compare them side by side with the latest scientific data to determine what is real and …

Making Lemonade Out Of Lyme, Kaela M. Gallagher

Social Sciences

No abstract provided.

Dairy Farming And Cattle Ranching; Consequences On Human And Environmental Health, Sarah Kensky

Social Sciences

No abstract provided.

Fetal Alcohol Spectrum Disorder, Mary (Katie) Busmire

Psychology and Child Development

This is a senior project about fetal alcohol spectrum disorder (FASD). Fetal Alcohol Spectrum Disorder (FASD) is the term given to a child who has been affected by exposure to prenatal alcohol. Drinking during pregnancy can lead to several physical, neurological and behavioral effects. However, there are several interventions that can help minimize the effects of prenatal alcohol. Focusing on family interventions and therapies will best benefit the lives of children with FASD and their families.

San Luis Obispo Wine And Culinary Center, Hayley Cole, Chad Endicott

City and Regional Planning

No abstract provided.

Poisonous Rangeland Plants In San Luis Obispo County, Sara Litten, Amanda Ou

Animal Science

Poisonous Rangeland Plants in San Luis Obispo County is a comprehensive educational guide to rangeland plants that are toxic to domestic livestock. This guide begins with an exploration of how the biological systems are affected by the poisonous plant toxins. The biochemistry behind these toxins is included in the discussion. Next, reference material for fourteen plants that inhabit San Luis Obispo County is provided. This information includes specific toxins found in poisonous plants, affected animals, symptoms of poisoning, stages of growth, lethal dose, and distribution of the plant in California. This section of the guide is filled with helpful photos …